Skeletal Muscle-Specific Ablation of raptor, but Not of rictor, Causes Metabolic Changes and Results in Muscle Dystrophy

Cell Metabolism

Volumn 8, Issue 5, 2008, Pages 411-424

  Bentzinger, C Florian ^a   Romanino, Klaas ^a   Cloëtta, Dimitri ^a   Lin, Shuo ^a   Mascarenhas, Joseph B ^a   Oliveri, Filippo ^a   Xia, Jinyu ^b   Casanova, Emilio ^c   Costa, Céline F ^a   Brink, Marijke ^c   Zorzato, Francesco ^b   Hall, Michael N ^a   Rüegg, Markus A ^a  

^a UNIVERSITY OF BASEL   (Switzerland)

^b UNIVERSITY HOSPITAL BASEL   (Switzerland)

^c UNIVERSITY OF BASEL   (Switzerland)

Author keywords

HUMDISEASE

Indexed keywords

GLYCOGEN; MAMMALIAN TARGET OF RAPAMYCIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PROTEIN KINASE B; RAPAMYCIN INSENSITIVE COMPANION OF MAMMALIAN TARGET OF RAPAMYCIN; REGULATOR PROTEIN; REGULATORY ASSOCIATED PROTEIN OF MAMMALIAN TARGET OF RAPAMYCIN; UNCLASSIFIED DRUG;

AEROBIC METABOLISM; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; GENE CONTROL; GLYCOGEN MUSCLE LEVEL; METABOLIC REGULATION; MITOCHONDRIAL RESPIRATION; MOUSE; MUSCLE FUNCTION; MUSCLE METABOLISM; MUSCULAR DYSTROPHY; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN FUNCTION; SURVIVAL RATE; WILD TYPE;

ANIMALS; CARRIER PROTEINS; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; MICE; MICE, KNOCKOUT; MITOCHONDRIA; MUSCLE, SKELETAL; MUSCULAR DYSTROPHIES; ONCOGENE PROTEIN V-AKT; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS;

MAMMALIA; RAPTORES;

EID: 54849426651     PISSN: 15504131     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cmet.2008.10.002     Document Type: Article

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