-
1
-
-
0030837555
-
P-TEN, the tumor suppressor from human chromosome 10q23, is a dual- Specificity phosphatase
-
DOI 10.1073/pnas.94.17.9052
-
Myers MP, Stolarov JP, Eng C, Li J, Wang SI, Wigler MH, Parsons R, Tonks NK: P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase. Proc Natl Acad Sci USA 1997, 94:9052-9057 (Pubitemid 27357780)
-
(1997)
Proceedings of the National Academy of Sciences of the United States of America
, vol.94
, Issue.17
, pp. 9052-9057
-
-
Myers, M.P.1
Stolarov, J.P.2
Eng, C.3
Li, J.4
Wang, S.I.5
Wigler, M.H.6
Parsons, R.7
Tonks, N.K.8
-
2
-
-
33646148946
-
Divergent regulation of hepatic glucose and lipid metabolism by phosphoinositide 3-kinase via Akt and PKClambda/zeta
-
Taniguchi CM, Kondo T, Sajan M, Luo J, Bronson R, Asano T, Farese R, Cantley LC, Kahn CR: Divergent regulation of hepatic glucose and lipid metabolism by phosphoinositide 3-kinase via Akt and PKClambda/zeta. Cell Metab 2006, 3:343-353
-
(2006)
Cell Metab
, vol.3
, pp. 343-353
-
-
Taniguchi, C.M.1
Kondo, T.2
Sajan, M.3
Luo, J.4
Bronson, R.5
Asano, T.6
Farese, R.7
Cantley, L.C.8
Kahn, C.R.9
-
3
-
-
85047694402
-
Hepatocyte-specific Pten deficiency results in steatohepatitis and hepatocellular carcinomas
-
Horie Y, Suzuki A, Kataoka E, Sasaki T, Hamada K, Sasaki J, Mizuno K, Hasegawa G, Kishimoto H, Iizuka M, Naito M, Enomoto K, Watanabe S, Mak TW, Nakano T: Hepatocyte-specific Pten deficiency results in steatohepatitis and hepatocellular carcinomas. J Clinl Invest 2004, 113:1774-1783
-
(2004)
J Clinl Invest
, vol.113
, pp. 1774-1783
-
-
Horie, Y.1
Suzuki, A.2
Kataoka, E.3
Sasaki, T.4
Hamada, K.5
Sasaki, J.6
Mizuno, K.7
Hasegawa, G.8
Kishimoto, H.9
Iizuka, M.10
Naito, M.11
Enomoto, K.12
Watanabe, S.13
Mak, T.W.14
Nakano, T.15
-
4
-
-
10744222107
-
Liver-specific deletion of negative regulator Pten results in fatty liver and insulin hypersensitivity
-
corrected. erratum appears in Proc Natl Acad Sci USA: 2004 Apr 6;101(14):5180
-
Stiles B, Wang Y, Stahl A, Bassilian S, Lee WP, Kim YJ, Sherwin R, Devaskar S, Lesche R, Magnuson MA, Wu H: Liver-specific deletion of negative regulator Pten results in fatty liver and insulin hypersensitivity [corrected]. [erratum appears in Proc Natl Acad Sci USA: 2004 Apr 6;101(14):5180]. Proc Natl Acad Sci USA 2004, 101:2082-2087
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 2082-2087
-
-
Stiles, B.1
Wang, Y.2
Stahl, A.3
Bassilian, S.4
Lee, W.P.5
Kim, Y.J.6
Sherwin, R.7
Devaskar, S.8
Lesche, R.9
Magnuson, M.A.10
Wu, H.11
-
6
-
-
1542781732
-
Isoform-specific regulation of insulin-dependent glucose uptake by Akt/protein kinase B
-
Bae SS, Cho H, Mu J, Birnbaum MJ: Isoform-specific regulation of insulin-dependent glucose uptake by Akt/protein kinase B. J Biol Chem 2003, 278:49530-49536
-
(2003)
J Biol Chem
, vol.278
, pp. 49530-49536
-
-
Bae, S.S.1
Cho, H.2
Mu, J.3
Birnbaum, M.J.4
-
7
-
-
0035368548
-
Insulin resistance and a diabetes mellitus-like syndrome in mice lacking the protein kinase Akt2 (PKB beta)
-
Cho H, Mu J, Kim JK, Thorvaldsen JL, Chu Q, Crenshaw EB 3rd, Kaestner KH, Bartolomei MS, Shulman GI, Birnbaum MJ: Insulin resistance and a diabetes mellitus-like syndrome in mice lacking the protein kinase Akt2 (PKB beta). Science 2001, 292:1728-1731
-
(2001)
Science
, vol.292
, pp. 1728-1731
-
-
Cho, H.1
Mu, J.2
Kim, J.K.3
Thorvaldsen, J.L.4
Chu, Q.5
Crenshaw III, E.B.6
Kaestner, K.H.7
Bartolomei, M.S.8
Shulman, G.I.9
Birnbaum, M.J.10
-
8
-
-
33745856213
-
Induction of intrahepatic cholangiocellular carcinoma by liver-specific disruption of Smad4 and Pten in mice
-
Xu X, Kobayashi S, Qiao W, Li C, Xiao C, Radaeva S, Stiles B, Wang RH, Ohara N, Yoshino T, LeRoith D, Torbenson MS, Gores GJ, Wu H, Gao B, Deng CX: Induction of intrahepatic cholangiocellular carcinoma by liver-specific disruption of Smad4 and Pten in mice. J Clin Invest 2006, 116:1843-1852
-
(2006)
J Clin Invest
, vol.116
, pp. 1843-1852
-
-
Xu, X.1
Kobayashi, S.2
Qiao, W.3
Li, C.4
Xiao, C.5
Radaeva, S.6
Stiles, B.7
Wang, R.H.8
Ohara, N.9
Yoshino, T.10
LeRoith, D.11
Torbenson, M.S.12
Gores, G.J.13
Wu, H.14
Gao, B.15
Deng, C.X.16
-
9
-
-
45749114635
-
Increased expression and activity of the transcription factor FOXO1 in nonalcoholic steatohepatitis
-
Valenti L, Rametta R, Dongiovanni P, Maggioni M, Fracanzani AL, Zappa M, Lattuada E, Roviaro G, Fargion S: Increased expression and activity of the transcription factor FOXO1 in nonalcoholic steatohepatitis. Diabetes 2008, 57:1355-1362
-
(2008)
Diabetes
, vol.57
, pp. 1355-1362
-
-
Valenti, L.1
Rametta, R.2
Dongiovanni, P.3
Maggioni, M.4
Fracanzani, A.L.5
Zappa, M.6
Lattuada, E.7
Roviaro, G.8
Fargion, S.9
-
10
-
-
33744515637
-
FoxO1 regulates multiple metabolic pathways in the liver: Effects on gluconeogenic, glycolytic, and lipogenic gene expression
-
Zhang W, Patil S, Chauhan B, Guo S, Powell DR, Le J, Klotsas A, Matika R, Xiao X, Franks R, Heidenreich KA, Sajan MP, Farese RV, Stolz DB, Tso P, Koo SH, Montminy M, Unterman TG: FoxO1 regulates multiple metabolic pathways in the liver: effects on gluconeogenic, glycolytic, and lipogenic gene expression. J Biol Chem 2006, 281:10105-10117
-
(2006)
J Biol Chem
, vol.281
, pp. 10105-10117
-
-
Zhang, W.1
Patil, S.2
Chauhan, B.3
Guo, S.4
Powell, D.R.5
Klotsas A, L.J.6
Matika, R.7
Xiao, X.8
Franks, R.9
Heidenreich, K.A.10
Sajan, M.P.11
Farese, R.V.12
Stolz, D.B.13
Tso, P.14
Koo, S.H.15
Montminy, M.16
Unterman, T.G.17
-
11
-
-
85047693348
-
Severe diabetes, age-dependent loss of adipose tissue, and mild growth deficiency in mice lacking Akt2/PKB beta
-
Garofalo RS, Orena SJ, Rafidi K, Torchia AJ, Stock JL, Hildebrandt AL, Coskran T, Black SC, Brees DJ, Wicks JR, McNeish JD, Coleman KG: Severe diabetes, age-dependent loss of adipose tissue, and mild growth deficiency in mice lacking Akt2/PKB beta. J Clin Invest 2003, 112:197-208
-
(2003)
J Clin Invest
, vol.112
, pp. 197-208
-
-
Garofalo, R.S.1
Orena, S.J.2
Rafidi, K.3
Torchia, A.J.4
Stock, J.L.5
Hildebrandt, A.L.6
Coskran, T.7
Black, S.C.8
Brees, D.J.9
Wicks, J.R.10
McNeish, J.D.11
Coleman, K.G.12
-
12
-
-
33750380920
-
Life with a single isoform of Akt: Mice lacking Akt2 and Akt3 are viable but display impaired glucose homeostasis and growth deficiencies
-
DOI 10.1128/MCB.00722-06
-
Dummler B, Tschopp O, Hynx D, Yang ZZ, Dirnhofer S, Hemmings BA: Life with a single isoform of Akt: mice lacking Akt2 and Akt3 are viable but display impaired glucose homeostasis and growth deficiencies. Mol Cell Biol 2006, 26:8042-8051 (Pubitemid 44631003)
-
(2006)
Molecular and Cellular Biology
, vol.26
, Issue.21
, pp. 8042-8051
-
-
Dummler, B.1
Tschopp, O.2
Hynx, D.3
Yang, Z.-Z.4
Dirnhofer, S.5
Hemmings, B.A.6
-
13
-
-
41449087811
-
Rapid Activation of Akt2 Is Sufficient to Stimulate GLUT4 Translocation in 3T3-L1 Adipocytes
-
DOI 10.1016/j.cmet.2008.02.008, PII S1550413108000429
-
Ng Y, Ramm G, Lopez JA, James DE: Rapid activation of Akt2 is sufficient to stimulate GLUT4 translocation in 3T3-L1 adipocytes. Cell Metabolism 2008, 7:348-356 (Pubitemid 351455217)
-
(2008)
Cell Metabolism
, vol.7
, Issue.4
, pp. 348-356
-
-
Ng, Y.1
Ramm, G.2
Lopez, J.A.3
James, D.E.4
-
14
-
-
46349103337
-
Isoform-specific regulation of adipocyte differentiation by Akt/protein kinase Balpha
-
Yun SJ, Kim EK, Tucker DF, Kim CD, Birnbaum MJ, Bae SS: Isoform-specific regulation of adipocyte differentiation by Akt/protein kinase Balpha. Biochem Biophys Res Commun 2008, 371:138-143
-
(2008)
Biochem Biophys Res Commun
, vol.371
, pp. 138-143
-
-
Yun, S.J.1
Kim, E.K.2
Tucker, D.F.3
Kim, C.D.4
Birnbaum, M.J.5
Bae, S.S.6
-
15
-
-
0142217895
-
PKClambda in liver mediates insulininduced SREBP-1c expression and determines both hepatic lipid content and overall insulin sensitivity
-
Matsumoto M, Ogawa W, Akimoto K, Inoue H, Miyake K, Furukawa K, Hayashi Y, Iguchi H, Matsuki Y, Hiramatsu R, Shimano H, Yamada N, Ohno S, Kasuga M, Noda T: PKClambda in liver mediates insulininduced SREBP-1c expression and determines both hepatic lipid content and overall insulin sensitivity. J Clin Invest 2003, 112:935-944
-
(2003)
J Clin Invest
, vol.112
, pp. 935-944
-
-
Matsumoto, M.1
Ogawa, W.2
Akimoto, K.3
Inoue, H.4
Miyake, K.5
Furukawa, K.6
Hayashi, Y.7
Iguchi, H.8
Matsuki, Y.9
Hiramatsu, R.10
Shimano, H.11
Yamada, N.12
Ohno, S.13
Kasuga, M.14
Noda, T.15
-
16
-
-
70350417158
-
AKT2 is required for hepatic lipid accumulation in models of insulin resistance
-
Leavens KF, Easton RM, Shulman GI, Previs SF, Birnbaum MJ: AKT2 is required for hepatic lipid accumulation in models of insulin resistance. Cell Metabolism 2009, 10:405-418.
-
(2009)
Cell Metabolism
, vol.10
, pp. 405-418
-
-
Leavens, K.F.1
Easton, R.M.2
Shulman, G.I.3
Previs, S.F.4
Birnbaum, M.J.5
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