SCOPUS 정보 검색 플랫폼

RSC Drug Discovery Series

Volumn 1, Issue 1, 2010, Pages 328-369

Chapter 7: Influence of heteroaromatic rings on ADME properties of drugs

(5) Dalvie, Deepak a Kang, Ping a Loi, Choming a Goulet, Lance a Nair, Sajiv a

a PFIZER INC (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINE; ADENINE; AROMATIC COMPOUND; CIMETIDINE; COCAINE; DASATINIB; EPROSARTAN; FLUOROURACIL; FURAN; GEFITINIB; GEMCITABINE; GUANINE; HETEROAROMATIC RING; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; IMATINIB; LOSARTAN; MEVINOLIN; MIANSERIN; MIRTAZAPINE; NILOTINIB; PROCAINE; PYRROLE; RAZAXABAN; RIZATRIPTAN; ROSIGLITAZONE; SUMATRIPTAN; TACRINE; TIMOLOL; TROGLITAZONE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

AREA UNDER THE CURVE; ARTICLE; CHRONIC MYELOID LEUKEMIA; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG DESIGN; DRUG DISTRIBUTION; DRUG ELIMINATION; DRUG EXCRETION; DRUG HALF LIFE; DRUG METABOLISM; DRUG STRUCTURE; DRUG TOXICITY; PHYSICAL CHEMISTRY;

EID: 84860269724 PISSN: 20413203 EISSN: 20413211 Source Type: Book Series
DOI: 10.1039/9781849731102-00328 Document Type: Article

Times cited : (18)

References (86)

1
- 4344612574
- H. B. Broughton I. A. Watson J. Mol. Graphics Modelling 2005 23 51
- (2005) J. Mol. Graphics Modelling , vol.23 , pp. 51
- Broughton, H.B.¹ Watson, I.A.²

2
- 15744405089
- S.W. Zhao L. Liu Y. Fu Q.X. Guo J. Phys. Org. Chem. 2005 18 353
- (2005) J. Phys. Org. Chem. , vol.18 , pp. 353
- Zhao, S.W.¹ Liu, L.² Fu, Y.³ Guo, Q.X.⁴

3
- 27844538344
- J. B. Sperry D. L. Wright Curr. Opin. Drug Discov. Dev. 2005 8 723
- (2005) Curr. Opin. Drug Discov. Dev. , vol.8 , pp. 723
- Sperry, J.B.¹ Wright, D.L.²

4
- 0003450582
- in, Academic Press, San Diego CA
- R. B. Silverman, in The Organic Chemistry of Drug Design and Drug Action, Academic Press, San Diego CA, 1992, pp. 88-95
- (1992) The Organic Chemistry of Drug Design and Drug Action , pp. 88-95
- Silverman, R.B.¹

5
- 43549124804
- P. P. A. Humphrey Headache 2008 48 685
- (2008) Headache , vol.48 , pp. 685
- Humphrey, P.P.A.¹

6
- 0033178359
- P. Cohen Curr. Opin. Chem. Biol. 1999 3 459
- (1999) Curr. Opin. Chem. Biol. , vol.3 , pp. 459
- Cohen, P.¹

7
- 1642323740
- M. E. M. Noble J. A. Endicott L. N. Johnson Science 2004 303 1800
- (2004) Science , vol.303 , pp. 1800
- Noble, M.E.M.¹ Endicott, J.A.² Johnson, L.N.³

8
- 0034306450
- S. P. Davies H. Reddy M. Caivano P. Cohen Biochem. J. 2000 351 95
- (2000) Biochem. J. , vol.351 , pp. 95
- Davies, S.P.¹ Reddy, H.² Caivano, M.³ Cohen, P.⁴

9
- 0031695495
- Y.Z. Shu J. Nat. Prod. 1998 61 1053
- (1998) J. Nat. Prod. , vol.61 , pp. 1053
- Shu, Y.Z.¹

10
- 11844255399
- L. M. Lima E. J. Barreiro Curr. Med. Chem. 2005 12 23
- (2005) Curr. Med. Chem. , vol.12 , pp. 23
- Lima, L.M.¹ Barreiro, E.J.²

11
- 0034924558
- P. H. Olesen Curr. Opin. Drug Discov. Dev. 2001 4 471
- (2001) Curr. Opin. Drug Discov. Dev. , vol.4 , pp. 471
- Olesen, P.H.¹

12
- 0028335891
- B. C. C. Cantello M. A. Cawthome D. Haigh R. M. Hindley S. A. Smith P. L. Thurlby Bio. Med. Chem. Lett. 1994 4 1181
- (1994) Bio. Med. Chem. Lett. , vol.4 , pp. 1181
- Cantello, B.C.C.¹ Cawthome, M.A.² Haigh, D.³ Hindley, R.M.⁴ Smith, S.A.⁵ Thurlby, P.L.⁶

13
- 0004061172
- in, Blackwell Publishing, Oxford
- J. A. Joule and K. Mills, in Heterocylic Chemistry, Blackwell Publishing, Oxford, 2000, pp. 1-15
- (2000) Heterocylic Chemistry , pp. 1-15
- Joule, J.A.¹ Mills, K.²

14
- 0004039074
- in, WileyVCH, Weinheim
- T. Eicher, S. Hauptmann and A. Speicher, in The Chemistry of Heterocycles, WileyVCH, Weinheim, 2003, pp. 5-16
- (2003) The Chemistry of Heterocycles , pp. 5-16
- Eicher, T.¹ Hauptmann, S.² Speicher, A.³

15
- 0003989782
- Longman Scientific & Technical, Harlow
- T. L. Gilchrist, Heterocyclic Chemistry, Longman Scientific & Technical, Harlow, 1985, pp. 5-30
- (1985) Heterocyclic Chemistry , pp. 5-30
- Gilchrist, T.L.¹

16
- 0029865450
- D. A. Smith B. C. Jones D. K. Walker Med. Res. Rev. 1996 16 243
- (1996) Med. Res. Rev. , vol.16 , pp. 243
- Smith, D.A.¹ Jones, B.C.² Walker, D.K.³

17
- 0000312699
- O. H. Chan B. H. Stewart Drug Discov. Today 1996 1 461
- (1996) Drug Discov. Today , vol.1 , pp. 461
- Chan, O.H.¹ Stewart, B.H.²

18
- 0034632752
- I. K. Khanna Y. Yu R. M. Huff R. M. Weier X. Xu F. J. Koszyk P. W. Collins J. N. Cogburn P. C. Isakson C. M. Koboldt J. L. Masferrer W. E. Perkins K. Seibert A. W. Veenhuizen J. Yuan D.C. Yang Y. Y. Zhang J. Med. Chem. 2000 43 3168
- (2000) J. Med. Chem. , vol.43 , pp. 3168
- Khanna, I.K.¹ Yu, Y.² Huff, R.M.³ Weier, R.M.⁴ Xu, X.⁵ Koszyk, F.J.⁶ Collins, P.W.⁷ Cogburn, J.N.⁸ Isakson, P.C.⁹ Koboldt, C.M.¹⁰ Masferrer, J.L.¹¹ Perkins, W.E.¹² Seibert, K.¹³ Veenhuizen, A.W.¹⁴ Yuan, J.¹⁵ Yang, D.C.¹⁶ Zhang, Y.Y.¹⁷

19
- 0033911580
- P. J. Cox D. A. Ryan F. J. Hollis A.M. Harris A. K. Miller M. Vousden H. Cowley Drug Metab. and Dispos. 2000 28 772
- (2000) Drug Metab. and Dispos. , vol.28 , pp. 772
- Cox, P.J.¹ Ryan, D.A.² Hollis, F.J.³ Harris, A.M.⁴ Miller, A.K.⁵ Vousden, M.⁶ Cowley, H.⁷

20
- 0032850352
- C.M. Loi M. Young E. Randinitis A. Vassos J. R. Koup Clin. Pharmacokinet. 1999 37 91
- (1999) Clin. Pharmacokinet. , vol.37 , pp. 91
- Loi, C.M.¹ Young, M.² Randinitis, E.³ Vassos, A.⁴ Koup, J.R.⁵

21
- 20144374942
- M. L. Quan P. Y. S. Lam Q. Han D. J. P. Pinto M. Y. He R. Li C. D. Ellis C. G. Clark C. A. Teleha J.H. Sun R. S. Alexander S. Bai J. M. Luettgen R. M. Knabb P. C. Wong R. R. Wexler J. Med. Chem. 2005 48 1729
- (2005) J. Med. Chem. , vol.48 , pp. 1729
- Quan, M.L.¹ Lam, P.Y.S.² Han, Q.³ Pinto, D.J.P.⁴ He, M.Y.⁵ Li, R.⁶ Ellis, C.D.⁷ Clark, C.G.⁸ Teleha, C.A.⁹ Sun, J.H.¹⁰ Alexander, R.S.¹¹ Bai, S.¹² Luettgen, J.M.¹³ Knabb, R.M.¹⁴ Wong, P.C.¹⁵ Wexler, R.R.¹⁶

22
- 1642494654
- B. Peng C. Dutreix G. Mehring M. J. Hayes M. BenAm M. Seiberling R. Pokomy R. Capdeville P. Lloyd J. Clin. Pharmacol. 2004 44 158
- (2004) J. Clin. Pharmacol. , vol.44 , pp. 158
- Peng, B.¹ Dutreix, C.² Mehring, G.³ Hayes, M.J.⁴ Benam, M.⁵ Seiberling, M.⁶ Pokomy, R.⁷ Capdeville, R.⁸ Lloyd, P.⁹

23
- 0036836947
- R. J. Herr Bioorg. Med. Chem. 2000 10 3379
- (2000) Bioorg. Med. Chem. , vol.10 , pp. 3379
- Herr, R.J.¹

24
- 0029588499
- M.W. Lo M. R. Goldberg J. B. McCrea H. Lu C. I. Furtek T. D. Bjornsson Clin. Pharmacol. Ther. 1995 58 641
- (1995) Clin. Pharmacol. Ther. , vol.58 , pp. 641
- Lo, M.W.¹ Goldberg, M.R.² McCrea, J.B.³ Lu, H.⁴ Furtek, C.I.⁵ Bjornsson, T.D.⁶

25
- 0002844644
- P. J. Cox B. D. Bush P. D. Gorycki G. Y. Kuo D. Kenworthy D. W. Law D. Murphy P. C. Shardlow A. Taylor J. W. Upward C. H. Compton R. D. Murdoch Exp. Tox. Pathol. 1996 48 75
- (1996) Exp. Tox. Pathol. , vol.48 , pp. 75
- Cox, P.J.¹ Bush, B.D.² Gorycki, P.D.³ Kuo, G.Y.⁴ Kenworthy, D.⁵ Law, D.W.⁶ Murphy, D.⁷ Shardlow, P.C.⁸ Taylor, A.⁹ Upward, J.W.¹⁰ Compton, C.H.¹¹ Murdoch, R.D.¹²

26
- 85069031072
- D. Teneroa D. Martinb B. Ilsonb J. Jushchyshync S. Boikeb D. Lundberga N. Zariffab D. Boylea D. Jorkaskyb Biopharm. Drug Dispos. 1998 19 351
- (1998) Biopharm. Drug Dispos. , vol.19 , pp. 351
- Teneroa, D.¹ Martinb, D.² Ilsonb, B.³ Jushchyshync, J.⁴ Boikeb, S.⁵ Lundberga, D.⁶ Zariffab, N.⁷ Boylea, D.⁸ Jorkaskyb, D.⁹

27
- 0037171833
- C. Liljebris S. D. Larsen D. Ogg B. J. Palazuk J. E. Bleasdale J. Med. Chem. 2002 45 1785
- (2002) J. Med. Chem. , vol.45 , pp. 1785
- Liljebris, C.¹ Larsen, S.D.² Ogg, D.³ Palazuk, B.J.⁴ Bleasdale, J.E.⁵

28
- 0032714220
- J. Kelder P. D. J. Grootenhuis D. M. Bayada L. P. C. Delbressine J.P. Ploemen Pharm. Res. 1999 16 1514
- (1999) Pharm. Res. , vol.16 , pp. 1514
- Kelder, J.¹ Grootenhuis, P.D.J.² Bayada, D.M.³ Delbressine, L.P.C.⁴ Ploemen, J.P.⁵

29
- 0030914681
- K. Palm P. Sternberg K. Luthman P. Artursson Pharm. Res. 1997 14 568
- (1997) Pharm. Res. , vol.14 , pp. 568
- Palm, K.¹ Sternberg, P.² Luthman, K.³ Artursson, P.⁴

30
- 0036896304
- K. M. Mahar Doan J. E. Humphreys L. O. Webster S. A. Wring L. J. Shampine C. J. SerabjitSingh K. K. Adkison J. W. Polli J. Pharmacol. Exp. Ther. 2002 303 1029
- (2002) J. Pharmacol. Exp. Ther. , vol.303 , pp. 1029
- Mahar Doan, K.M.¹ Humphreys, J.E.² Webster, L.O.³ Wring, S.A.⁴ Shampine, L.J.⁵ Serabjitsingh, C.J.⁶ Adkison, K.K.⁷ Polli, J.W.⁸

31
- 33845937770
- S. A. Hitchcock L. D. Pennington J. Med. Chem. 2006 49 7559
- (2006) J. Med. Chem. , vol.49 , pp. 7559
- Hitchcock, S.A.¹ Pennington, L.D.²

32
- 17144370948
- R. Tatsumi M. Fujio H. Satoh J. Katayama S.I. Takanashi K. Hashimoto H. Tanaka J. Med. Chem. 2005 48 2678
- (2005) J. Med. Chem. , vol.48 , pp. 2678
- Tatsumi, R.¹ Fujio, M.² Satoh, H.³ Katayama, J.⁴ Takanashi, S.I.⁵ Hashimoto, K.⁶ Tanaka, H.⁷

33
- 0035939299
- R. A. Porter W. N. Chan S. Coulton A. Johns M. S. Hadley K. Widdowson J. J. C. Jerman S. J. Brough M. Coldwell D. Smart F. Jewitt P. Jeffrey N. Austin Bioorg. Med. Chem. Lett. 2001 11 1907
- (2001) Bioorg. Med. Chem. Lett. , vol.11 , pp. 1907
- Porter, R.A.¹ Chan, W.N.² Coulton, S.³ Johns, A.⁴ Hadley, M.S.⁵ Widdowson, K.⁶ Jerman, J.J.C.⁷ Brough, S.J.⁸ Coldwell, M.⁹ Smart, D.¹⁰ Jewitt, F.¹¹ Jeffrey, P.¹² Austin, N.¹³

34
- 0030043963
- J. L. Castro R. G. Ball H. B. Broughton M. G. N. Russell D. Rathbone A. P. Watt R. Baker K. L. Chapman A. E. Fletcher S. Patel A. J. Smith G. R. Marshall W. Ryecroft V. G. Matassa J. Med. Chem. 1996 39 842
- (1996) J. Med. Chem. , vol.39 , pp. 842
- Castro, J.L.¹ Ball, R.G.² Broughton, H.B.³ Russell, M.G.N.⁴ Rathbone, D.⁵ Watt, A.P.⁶ Baker, R.⁷ Chapman, K.L.⁸ Fletcher, A.E.⁹ Patel, S.¹⁰ Smith, A.J.¹¹ Marshall, G.R.¹² Ryecroft, W.¹³ Matassa, V.G.¹⁴

35
- 7044235517
- A. B. Pinkerton R. V. Cube J. H. Hutchinson J. K. James M. F. Gardner H. Schaffhauser B. A. Rowe L. P. Daggett J.M. Vernier Bioorg. Med. Chem. Lett. 2004 14 5867
- (2004) Bioorg. Med. Chem. Lett. , vol.14 , pp. 5867
- Pinkerton, A.B.¹ Cube, R.V.² Hutchinson, J.H.³ James, J.K.⁴ Gardner, M.F.⁵ Schaffhauser, H.⁶ Rowe, B.A.⁷ Daggett, L.P.⁸ Vernier, J.M.⁹

36
- 34247558084
- N. Murayama N. Imai T. Nakane M. Shimizu H. Yamazaki Biochem. Pharmacol. 2007 73 2020
- (2007) Biochem. Pharmacol. , vol.73 , pp. 2020
- Murayama, N.¹ Imai, N.² Nakane, T.³ Shimizu, M.⁴ Yamazaki, H.⁵

37
- 0037403687
- R. Hyland B. C. Jones D. A. Smith Drug Metab. Dispos. 2003 31 540
- (2003) Drug Metab. Dispos. , vol.31 , pp. 540
- Hyland, R.¹ Jones, B.C.² Smith, D.A.³

38
- 0028868234
- S. K. Balani B. H. Arison L. Mathai L. Kauffman R. R. Miller R. A. Steams I.W. Chen J. H. Lin Drug Metab. Dispos. 1995 23 266
- (1995) Drug Metab. Dispos. , vol.23 , pp. 266
- Balani, S.K.¹ Arison, B.H.² Mathai, L.³ Kauffman, L.⁴ Miller, R.R.⁵ Steams, R.A.⁶ Chen, I.W.⁷ Lin, J.H.⁸

39
- 0030908131
- M. Chiba M. Hensleigh J. H. Lin Biochem. Pharmacol. 1997 53 1187
- (1997) Biochem. Pharmacol. , vol.53 , pp. 1187
- Chiba, M.¹ Hensleigh, M.² Lin, J.H.³

40
- 0036893113
- O. Ghosheh E. M. Hawes Drug Metab. Dispos. 2002 30 1478
- (2002) Drug Metab. Dispos. , vol.30 , pp. 1478
- Ghosheh, O.¹ Hawes, E.M.²

41
- 0026725358
- J. Magdalou R. Herber R. Bidault G. Siest J. Pharmacol. Exp. Ther. 1992 260 1166
- (1992) J. Pharmacol. Exp. Ther. , vol.260 , pp. 1166
- Magdalou, J.¹ Herber, R.² Bidault, R.³ Siest, G.⁴

42
- 33744979094
- S. Kitamura K. Sugihara S. Ohta Drug Metab. Pharmacokinet. 2006 21 83
- (2006) Drug Metab. Pharmacokinet. , vol.21 , pp. 83
- Kitamura, S.¹ Sugihara, K.² Ohta, S.³

43
- 0030840879
- M. R. Rashidi J. A. Smith S. E. Clarke C. Beedham Drug Metab. Dispos. 1997 25 805
- (1997) Drug Metab. Dispos. , vol.25 , pp. 805
- Rashidi, M.R.¹ Smith, J.A.² Clarke, S.E.³ Beedham, C.⁴

44
- 0023037533
- W. W. Hall T. A. Krenitsky Arch. Biochem. Biophys. 1986 251 36
- (1986) Arch. Biochem. Biophys. , vol.251 , pp. 36
- Hall, W.W.¹ Krenitsky, T.A.²

45
- 0036127307
- D. K. Dalvie A. S. Kalgutkar S. C. KhojastehBakht R. S. Obach J. P. O'Donnell Chem. Res. Toxicol. 2002 15 269
- (2002) Chem. Res. Toxicol. , vol.15 , pp. 269
- Dalvie, D.K.¹ Kalgutkar, A.S.² Khojastehbakht, S.C.³ Obach, R.S.⁴ O'Donnell, J.P.⁵

46
- 0018120848
- D. C. Hobbs T. M. Twomey R. F. Palmer J. Clin. Pharmacol. 1978 18 402
- (1978) J. Clin. Pharmacol. , vol.18 , pp. 402
- Hobbs, D.C.¹ Twomey, T.M.² Palmer, R.F.³

47
- 84860305890
- in, ed. D. A. Williams and T. L. Lemke, Lippincott Williams and Wilkins, Philadelphia
- R. Griffith, in Foye's Principles of Medicinal Chemistry, ed., D. A. Williams, and, T. L. Lemke, Lippincott Williams and Wilkins, Philadelphia, 2002, pp. 292-312
- (2002) Foye's Principles of Medicinal Chemistry , pp. 292-312
- Griffith, R.¹

48
- 84860285222
- J. J. Kyncl R. C. Sonders W. D. Sperzel M. Winn J. H. Seely Cardiovasc. Drug Rev. 1986 4 1
- (1986) Cardiovasc. Drug Rev. , vol.4 , pp. 1
- Kyncl, J.J.¹ Sonders, R.C.² Sperzel, W.D.³ Winn, M.⁴ Seely, J.H.⁵

49
- 84860307413
- K. Sugihara S. Kitamura K. Tatsumi Comp. Biochem. Physiol. 1996 24 1996
- (1996) Comp. Biochem. Physiol. , vol.24 , pp. 1996
- Sugihara, K.¹ Kitamura, S.² Tatsumi, K.³

50
- 0038722339
- C. Beedham J. J. Miceli R. S. Obach J. Clin. Psychopharmacol. 2003 23 229
- (2003) J. Clin. Psychopharmacol. , vol.23 , pp. 229
- Beedham, C.¹ Miceli, J.J.² Obach, R.S.³

51
- 22344442353
- Z. Miao A. Kamel C. Prakash Drug Metab. Dispos. 2005 33 879
- (2005) Drug Metab. Dispos. , vol.33 , pp. 879
- Miao, Z.¹ Kamel, A.² Prakash, C.³

52
- 38749094445
- D. Zhang N. Raghavan S.Y. Chen H. Zhang M. Quan L. Lecureux L. M. Patrone P. Y. S. Lam S. J. Bonacorsi R. M. Knabb G. L. Skiles K. He Drug Metab. Dispos. 2008 36 303
- (2008) Drug Metab. Dispos. , vol.36 , pp. 303
- Zhang, D.¹ Raghavan, N.² Chen, S.Y.³ Zhang, H.⁴ Quan, M.⁵ Lecureux, L.⁶ Patrone, L.M.⁷ Lam, P.Y.S.⁸ Bonacorsi, S.J.⁹ Knabb, R.M.¹⁰ Skiles, G.L.¹¹ He, K.¹²

53
- 0026611521
- P. Sauerberg P. H. Olesen S. Nielsen S. Treppendahl M. J. Sheardown T. Honor C. H. Mitch J. S. Ward A. J. Pike F. P. Bymaster B. D. Sawyer H. E. Shannon J. Med. Chem. 1992 35 2274
- (1992) J. Med. Chem. , vol.35 , pp. 2274
- Sauerberg, P.¹ Olesen, P.H.² Nielsen, S.³ Treppendahl, S.⁴ Sheardown, M.J.⁵ Honor, T.⁶ Mitch, C.H.⁷ Ward, J.S.⁸ Pike, A.J.⁹ Bymaster, F.P.¹⁰ Sawyer, B.D.¹¹ Shannon, H.E.¹²

54
- 0026062275
- P. Sauerberg J. W. Kindtler L. Nielsen M. J. Sheardown T. Honor J. Med.Chem. 1991 34 687
- (1991) J. Med.Chem. , vol.34 , pp. 687
- Sauerberg, P.¹ Kindtler, J.W.² Nielsen, L.³ Sheardown, M.J.⁴ Honor, T.⁵

55
- 0025923336
- K. W. Brammer A. J. Coakley S. G. Jezequel M. H. Tarbit Drug Metab. Dispos. 1991 19 764
- (1991) Drug Metab. Dispos. , vol.19 , pp. 764
- Brammer, K.W.¹ Coakley, A.J.² Jezequel, S.G.³ Tarbit, M.H.⁴

56
- 0026561612
- R. A. Stearns R. R. Miller G. A. Doss P. K. Chakravarty A. Rosegay G. J. Gatto G.H. Chiu Drug Metab. Dispos. 1992 20 281
- (1992) Drug Metab. Dispos. , vol.20 , pp. 281
- Stearns, R.A.¹ Miller, R.R.² Doss, G.A.³ Chakravarty, P.K.⁴ Rosegay, A.⁵ Gatto, G.J.⁶ Chiu, G.H.⁷

57
- 0027451525
- S. W. Huskey R. R. Miller S.H. Chiu Drug Metab. Dispos. 1993 21 792
- (1993) Drug Metab. Dispos. , vol.21 , pp. 792
- Huskey, S.W.¹ Miller, R.R.² Chiu, S.H.³

58
- 0031902451
- T. J. Chando D. W. Everett A. D. Kahle A. M. Starrett N. Vachharajani W. C. Shyu K. J. Kripalani R. H. Barbhaiya Drug Metab. Dispos. 1998 26 408
- (1998) Drug Metab. Dispos. , vol.26 , pp. 408
- Chando, T.J.¹ Everett, D.W.² Kahle, A.D.³ Starrett, A.M.⁴ Vachharajani, N.⁵ Shyu, W.C.⁶ Kripalani, K.J.⁷ Barbhaiya, R.H.⁸

59
- 0025257110
- K. W. Brammer P. R. Farrow J. K. Faulkner Rev. Infect. Dis. 1990 12 Suppl 3 S318
- (1990) Rev. Infect. Dis. , vol.12 , Issue.SUPPL 3 , pp. 318
- Brammer, K.W.¹ Farrow, P.R.² Faulkner, J.K.³

60
- 0023734842
- T. C. Hardin J. R. Graybill R. Fetchick R. Woestenborghs M. G. Rinaldi J. G. Kuhn Antimicrob. Agents Chemother. 1988 32 1310
- (1988) Antimicrob. Agents Chemother. , vol.32 , pp. 1310
- Hardin, T.C.¹ Graybill, J.R.² Fetchick, R.³ Woestenborghs, R.⁴ Rinaldi, M.G.⁵ Kuhn, J.G.⁶

61
- 4344700227
- P. Krieter B. Flannery T. Musick M. Gohdes M. Martinho R. Courtney Antimicrob. Agents Chemother. 2004 48 3543
- (2004) Antimicrob. Agents Chemother. , vol.48 , pp. 3543
- Krieter, P.¹ Flannery, B.² Musick, T.³ Gohdes, M.⁴ Martinho, M.⁵ Courtney, R.⁶

62
- 33645974899
- D. Levêque Y. Nivoix F. Jehl Raoul Herbrecht Int. J. Antimicrob. Agents 2006 27 274
- (2006) Int. J. Antimicrob. Agents , vol.27 , pp. 274
- Levêque, D.¹ Nivoix, Y.² Jehl, F.³ Herbrecht, R.⁴

63
- 0037855889
- S. J. Roffey S. Cole P. Comby D. Gibson S. G. Jezequel A. N. R. Nedderman D. A. Smith D. K. Walker N. Wood Drug Metab. Dispos. 2003 31 731
- (2003) Drug Metab. Dispos. , vol.31 , pp. 731
- Roffey, S.J.¹ Cole, S.² Comby, P.³ Gibson, D.⁴ Jezequel, S.G.⁵ Nedderman, A.N.R.⁶ Smith, D.A.⁷ Walker, D.K.⁸ Wood, N.⁹

64
- 33947690115
- N. A. Thornberry A. E. Weber Curr. Topics Med. Chem. 2007 7 557
- (2007) Curr. Topics Med. Chem. , vol.7 , pp. 557
- Thornberry, N.A.¹ Weber, A.E.²

65
- 34247236764
- X.Y. Chu K. Bleasby J. Yabut X. Cai G. H. Chan M. J. Hafey S. Xu A. J. Bergman M. P. Braun D. C. Dean R. Evers J. Pharmacol. Exp. Ther. 2007 321 673
- (2007) J. Pharmacol. Exp. Ther. , vol.321 , pp. 673
- Chu, X.Y.¹ Bleasby, K.² Yabut, J.³ Cai, X.⁴ Chan, G.H.⁵ Hafey, M.J.⁶ Xu, S.⁷ Bergman, A.J.⁸ Braun, M.P.⁹ Dean, D.C.¹⁰ Evers, R.¹¹

66
- 1342344851
- W. Lee R. B. Kim Annu. Rev. Pharmacol. Toxicol. 2004 44 137
- (2004) Annu. Rev. Pharmacol. Toxicol. , vol.44 , pp. 137
- Lee, W.¹ Kim, R.B.²

67
- 0028927525
- I. B. Gardner D. K. Walker M. S. Lennard D. A. Smith G. T. Tucker Xenobiotica 1995 25 185
- (1995) Xenobiotica , vol.25 , pp. 185
- Gardner, I.B.¹ Walker, D.K.² Lennard, M.S.³ Smith, D.A.⁴ Tucker, G.T.⁵

68
- 0037297445
- K. Samuel W. Yin R. A. Stearns Y. S. Tang A. G. Chaudhary J. P. Jewell T. Lanza L. S. Lin W. K. Hagman D. C. Evans S. Kumar J. Mass Spectrom. 2003 38 211
- (2003) J. Mass Spectrom. , vol.38 , pp. 211
- Samuel, K.¹ Yin, W.² Stearns, R.A.³ Tang, Y.S.⁴ Chaudhary, A.G.⁵ Jewell, J.P.⁶ Lanza, T.⁷ Lin, L.S.⁸ Hagman, W.K.⁹ Evans, D.C.¹⁰ Kumar, S.¹¹

69
- 51249100615
- Y.Z. Shu B. M. Johnson T. J. Yang AAPS J. 2008 10 178
- (2008) AAPS J. , vol.10 , pp. 178
- Shu, Y.Z.¹ Johnson, B.M.² Yang, T.J.³

70
- 19944399431
- A. S. Kalgutkar I. Gardner R. S. Obach C. L. Shaffer E. Callegari K. R. Henne A. E. Mutlib D. K. Dalvie J. S. Lee Y. Nakai J. P. O'Donnell J. Boer S. P. Harriman Curr. Drug Metab. 2005 6 161
- (2005) Curr. Drug Metab. , vol.6 , pp. 161
- Kalgutkar, A.S.¹ Gardner, I.² Obach, R.S.³ Shaffer, C.L.⁴ Callegari, E.⁵ Henne, K.R.⁶ Mutlib, A.E.⁷ Dalvie, D.K.⁸ Lee Nakai Y, J.S.⁹ O'Donnell, J.P.¹⁰ Boer, J.¹¹ Harriman, S.P.¹²

71
- 34548805504
- A. S. Kalgutkar R. S. Obach T. S. Maurer Curr. Drug Metab. 2007 8 407
- (2007) Curr. Drug Metab. , vol.8 , pp. 407
- Kalgutkar, A.S.¹ Obach, R.S.² Maurer, T.S.³

72
- 0142150012
- J. P. O'Donnell D. K. Dalvie A. S. Kalgutkar R. S. Obach Drug Metab. Dispos. 2003 31 1369
- (2003) Drug Metab. Dispos. , vol.31 , pp. 1369
- O'Donnell, J.P.¹ Dalvie, D.K.² Kalgutkar, A.S.³ Obach, R.S.⁴

73
- 58149463629
- J. M. Hutzler L. M. Balogh M. Zientek V. Kumar T. S. Tracy Drug Metab. Dispos. 2009 37 59
- (2009) Drug Metab. Dispos. , vol.37 , pp. 59
- Hutzler, J.M.¹ Balogh, L.M.² Zientek, M.³ Kumar, V.⁴ Tracy, T.S.⁵

74
- 24944510505
- E. Fontana P. M. Dansette S. M. Poli Curr. Drug Metab. 2005 6 413
- (2005) Curr. Drug Metab. , vol.6 , pp. 413
- Fontana, E.¹ Dansette, P.M.² Poli, S.M.³

75
- 9444287125
- T. M. AlvarezDiez J. Zheng Drug Metab. Dispos. 2004 32 1345
- (2004) Drug Metab. Dispos. , vol.32 , pp. 1345
- Alvarezdiez, T.M.¹ Zheng, J.²

76
- 1342310586
- T. M. AlvarezDiez J. Zheng Chem. Res. Toxicol. 2004 17 150
- (2004) Chem. Res. Toxicol. , vol.17 , pp. 150
- Alvarezdiez, T.M.¹ Zheng, J.²

77
- 34548103826
- D. P Williams D. J Antoine P. J. Butler R. Jones L. Randle A. Payne M. Howard I. Gardner J. Blagg B. K. Park J. Pharmacol. Exp. Ther. 2007 322 1208
- (2007) J. Pharmacol. Exp. Ther. , vol.322 , pp. 1208
- Williams D, P.¹ Antoine D, J.² Butler, P.J.³ Jones, R.⁴ Randle, L.⁵ Payne, A.⁶ Howard, M.⁷ Gardner, I.⁸ Blagg, J.⁹ Park, B.K.¹⁰

78
- 0029741202
- Y. SahaliSahly S. K. Balani J. H. Lin T. A. Baillie Chem. Res. Toxicol. 1996 9 1007
- (1996) Chem. Res. Toxicol. , vol.9 , pp. 1007
- Sahalisahly, Y.¹ Balani, S.K.² Lin, J.H.³ Baillie, T.A.⁴

79
- 0034031395
- J. H. Lin I. W. Chen M. Chiba J. A. Nishime F. A. Deluna Drug Metab. Dispos. 2000 28 460
- (2000) Drug Metab. Dispos. , vol.28 , pp. 460
- Lin, J.H.¹ Chen, I.W.² Chiba, M.³ Nishime, J.A.⁴ Deluna, F.A.⁵

80
- 0029023852
- J. H. Lin M. Chiba I. W. Chen J. Pharmacol. Exp. Ther. 1995 274 264
- (1995) J. Pharmacol. Exp. Ther. , vol.274 , pp. 264
- Lin, J.H.¹ Chiba, M.² Chen, I.W.³

81
- 0029553030
- M. Chiba J. A. Nishime J. H. Lin J. Pharmacol. Exp. Ther. 1995 275 1527
- (1995) J. Pharmacol. Exp. Ther. , vol.275 , pp. 1527
- Chiba, M.¹ Nishime, J.A.² Lin, J.H.³

82
- 41249088785
- J. J. Chen K. Biswas Prog. Med. Chem. 2008 46 173
- (2008) Prog. Med. Chem. , vol.46 , pp. 173
- Chen, J.J.¹ Biswas, K.²

83
- 0036176695
- W. Zhang Y. Ramamoorthy T. Kilicarslan H. Nolte R. F. Tyndale E. M. Sellers Drug Metab. Dispos. 2002 30 314
- (2002) Drug Metab. Dispos. , vol.30 , pp. 314
- Zhang, W.¹ Ramamoorthy, Y.² Kilicarslan, T.³ Nolte, H.⁴ Tyndale, R.F.⁵ Sellers, E.M.⁶

84
- 0030908183
- S. W. Grimm M. C. Dyroff Drug Metab. Dispos. 1997 25 598
- (1997) Drug Metab. Dispos. , vol.25 , pp. 598
- Grimm, S.W.¹ Dyroff, M.C.²

85
- 0035152161
- M. Chiba L. Jin W. Neway J. P. Vacca J. R. Tata K. Chapman J. H. Lin Drug Metab. Dispos. 2001 29 1
- (2001) Drug Metab. Dispos. , vol.29 , pp. 1
- Chiba, M.¹ Jin, L.² Neway, W.³ Vacca, J.P.⁴ Tata, J.R.⁵ Chapman, K.⁶ Lin, J.H.⁷

86
- 5144233794
- N. D. Smith S. F. Poon D. Huang M. Green C. King L. Tehrani J. R. Roppe J. Chung D. P. Chapman M. Cramera N. D. P. Cosforda Bio. Med. Chem. Lett. 2004 14 5481
- (2004) Bio. Med. Chem. Lett. , vol.14 , pp. 5481
- Smith, N.D.¹ Poon, S.F.² Huang, D.³ Green, M.⁴ King, C.⁵ Tehrani, L.⁶ Roppe, J.R.⁷ Chung, J.⁸ Chapman, D.P.⁹ Cramera, M.¹⁰ Cosforda, N.D.P.¹¹

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