-
1
-
-
17544396164
-
Activators of peroxisome proliferator-activated receptor gamma have depot-specific effects on human preadipocyte differentiation
-
Adams M, Montague CT, Prins JB, Holder JC, Smith SA, Sanders L, Digby JE, Sewter CP, Lazar MA, Chatterjee KK and O'Rahilly S (1997) Activators of peroxisome proliferator-activated receptor gamma have depot-specific effects on human preadipocyte differentiation. J Clin Invest 100:3149-3153.
-
(1997)
J Clin Invest
, vol.100
, pp. 3149-3153
-
-
Adams, M.1
Montague, C.T.2
Prins, J.B.3
Holder, J.C.4
Smith, S.A.5
Sanders, L.6
Digby, J.E.7
Sewter, C.P.8
Lazar, M.A.9
Chatterjee, K.K.10
O'Rahilly, S.11
-
2
-
-
0029745382
-
Thiazolidinediones produce a conformational change in peroxisomal proliferator-activated receptor-γ: Binding and activation correlate with antidiabetic actions in db/db mice
-
Berger J, Bailey P, Biswas C, Cullinan CA, Doebber TW, Hayes NS, Saperstein R, Smith RG and Leibowitz MD (1996) Thiazolidinediones produce a conformational change in peroxisomal proliferator-activated receptor-γ: Binding and activation correlate with antidiabetic actions in db/db mice. Endocrinology 137:4189-4195.
-
(1996)
Endocrinology
, vol.137
, pp. 4189-4195
-
-
Berger, J.1
Bailey, P.2
Biswas, C.3
Cullinan, C.A.4
Doebber, T.W.5
Hayes, N.S.6
Saperstein, R.7
Smith, R.G.8
Leibowitz, M.D.9
-
3
-
-
0029900481
-
The fate of a thiazolidinedione antidiabetic agent in rat and dog
-
Bolton GC, Keogh JP, East PB, Hollis FJ and Shore AD (1996) The fate of a thiazolidinedione antidiabetic agent in rat and dog. Xenobiotica 26:627-636.
-
(1996)
Xenobiotica
, vol.26
, pp. 627-636
-
-
Bolton, G.C.1
Keogh, J.P.2
East, P.B.3
Hollis, F.J.4
Shore, A.D.5
-
4
-
-
0018155445
-
Critical evaluation of the potential error in pharmacokinetic studies of using the linear trapezoidal rule method for the calculation of the area under the plasma level-time curve
-
Chiou WL (1978) Critical evaluation of the potential error in pharmacokinetic studies of using the linear trapezoidal rule method for the calculation of the area under the plasma level-time curve. J Pharmacokinet Biopharm 6:539-547.
-
(1978)
J Pharmacokinet Biopharm
, vol.6
, pp. 539-547
-
-
Chiou, W.L.1
-
5
-
-
0030462770
-
The peroxisome proliferator-activated receptors: Ligand and activators
-
Forman BM, Chen J and Evans RM (1996) The peroxisome proliferator-activated receptors: Ligand and activators. Ann NY Acad Sci 804:266-274.
-
(1996)
Ann NY Acad Sci
, vol.804
, pp. 266-274
-
-
Forman, B.M.1
Chen, J.2
Evans, R.M.3
-
6
-
-
0029847076
-
Peroxisome proliferator-activaled receptor gamma activation by thiazolidinediones induces adipogenesis in bone marrow stromal cells
-
Gimble JM, Robinson CE, Wu X, Kelly KA, Rodriguez BR, Kliewer SA, Lehmann JM and Morris DC (1996) Peroxisome proliferator-activaled receptor gamma activation by thiazolidinediones induces adipogenesis in bone marrow stromal cells. Mol Pharmacol 50:1087-1094.
-
(1996)
Mol Pharmacol
, vol.50
, pp. 1087-1094
-
-
Gimble, J.M.1
Robinson, C.E.2
Wu, X.3
Kelly, K.A.4
Rodriguez, B.R.5
Kliewer, S.A.6
Lehmann, J.M.7
Morris, D.C.8
-
8
-
-
0030848473
-
Regulation of lipoprotein metabolism by thiazolidinediones occurs through a distinct but complementary mechanism relative to fibrates
-
Lefebvre A-M, Peinado-Onsurbe J, Leitersdorf I, Briggs MR, Paterniti JR, Fruchart J-C, Fievet C, Auwerx J and Staels B (1997) Regulation of lipoprotein metabolism by thiazolidinediones occurs through a distinct but complementary mechanism relative to fibrates. Arterioscler Thromb Vasc Biol 17:1756-1764.
-
(1997)
Arterioscler Thromb Vasc Biol
, vol.17
, pp. 1756-1764
-
-
Lefebvre, A.-M.1
Peinado-Onsurbe, J.2
Leitersdorf, I.3
Briggs, M.R.4
Paterniti, J.R.5
Fruchart, J.-C.6
Fievet, C.7
Auwerx, J.8
Staels, B.9
-
9
-
-
0029016829
-
An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor γ (PPARγ)
-
Lehmann JM, Moore LB, Smith-Oliver TA, Wilkison WO, Willson TM and Kliewer SA (1995) An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor γ (PPARγ). J Biol Chem 270:12953-12956.
-
(1995)
J Biol Chem
, vol.270
, pp. 12953-12956
-
-
Lehmann, J.M.1
Moore, L.B.2
Smith-Oliver, T.A.3
Wilkison, W.O.4
Willson, T.M.5
Kliewer, S.A.6
-
10
-
-
0030658022
-
Co-ordinate regulation of the expression of the fatty acid transport protein and acyl-CoA synthetase genes by PPAR alpha and PPAR gamma activators
-
Martin G, Schoonjans K, Lefebvre A-M, Staels B and Auwerx J (1997) Co-ordinate regulation of the expression of the fatty acid transport protein and acyl-CoA synthetase genes by PPAR alpha and PPAR gamma activators. J Biol Chem 272:28210-28217.
-
(1997)
J Biol Chem
, vol.272
, pp. 28210-28217
-
-
Martin, G.1
Schoonjans, K.2
Lefebvre, A.-M.3
Staels, B.4
Auwerx, J.5
-
11
-
-
0000224547
-
Rosiglitazone decreases insulin resistance and improves beta-cell function in patients with type 2 diabetes
-
Matthews DR, Bakst A, Weston WM and Hemyari P (1999) Rosiglitazone decreases insulin resistance and improves beta-cell function in patients with type 2 diabetes. Diabetologia 42 (Suppl 1):A228.
-
(1999)
Diabetologia
, vol.42
, Issue.SUPPL. 1
-
-
Matthews, D.R.1
Bakst, A.2
Weston, W.M.3
Hemyari, P.4
-
12
-
-
0032479423
-
Expression of putative fatty acid transporter genes are regulated by peroxisome proliferator-activated receptor alpha and gamma activators in a tissue-and inducer-specific manner
-
Motojima K, Passilly P, Peters JM, Gonzalez FJ and Latruffe N (1998) Expression of putative fatty acid transporter genes are regulated by peroxisome proliferator-activated receptor alpha and gamma activators in a tissue-and inducer-specific manner. J Biol Chem 273:16710-16714.
-
(1998)
J Biol Chem
, vol.273
, pp. 16710-16714
-
-
Motojima, K.1
Passilly, P.2
Peters, J.M.3
Gonzalez, F.J.4
Latruffe, N.5
-
13
-
-
0001677801
-
Rosiglitazone (BRL49653) monotherapy has significant glucose lowering effect in type 2 diabetic patients
-
Patel J, Miller E, Patwardhan R and Rosiglitazone 011 Study Group (1998) Rosiglitazone (BRL49653) monotherapy has significant glucose lowering effect in type 2 diabetic patients. Diabetes 47 (Suppl 1):A17.
-
(1998)
Diabetes
, vol.47
, Issue.SUPPL. 1
-
-
Patel, J.1
Miller, E.2
Patwardhan, R.3
-
14
-
-
0030600556
-
The thiazolidinedione insulin sensitiser, BRL 49653, increases the expression of PPAR gamma and aP2 in adipose tissue of high-fat fed rats
-
Pearson SL, Cawthorne MA, Clapham JC, Dunmore SJ, Holmes SD, Moore GBT, Smith SA and Tadayyon M (1996) The thiazolidinedione insulin sensitiser, BRL 49653, increases the expression of PPAR gamma and aP2 in adipose tissue of high-fat fed rats. Biochem Biophys Res Comm 229:752-757.
-
(1996)
Biochem Biophys Res Comm
, vol.229
, pp. 752-757
-
-
Pearson, S.L.1
Cawthorne, M.A.2
Clapham, J.C.3
Dunmore, S.J.4
Holmes, S.D.5
Moore, G.B.T.6
Smith, S.A.7
Tadayyon, M.8
-
15
-
-
0031979733
-
Insulin-sensitising agents
-
Perry C and Petrie JR (1998) Insulin-sensitising agents. Emerging Drugs 3:247-260.
-
(1998)
Emerging Drugs
, vol.3
, pp. 247-260
-
-
Perry, C.1
Petrie, J.R.2
-
16
-
-
0029791412
-
PPAR alpha and PPAR gamma activators direct a distinct tissue-specific transcriptional response via a PPRE in the lipoprotein lipase gene
-
Schoonjans K, Peinado-Onsurbe J, Lefebvre A-M, Heyman RA, Briggs M, Deeb S, Staels B and Auwerx J (1996) PPAR alpha and PPAR gamma activators direct a distinct tissue-specific transcriptional response via a PPRE in the lipoprotein lipase gene. Embo J 15:5336-5348.
-
(1996)
Embo J
, vol.15
, pp. 5336-5348
-
-
Schoonjans, K.1
Peinado-Onsurbe, J.2
Lefebvre, A.-M.3
Heyman, R.A.4
Briggs, M.5
Deeb, S.6
Staels, B.7
Auwerx, J.8
-
17
-
-
10544229796
-
Activation of the nuclear receptor peroxisome proliferator-activated receptor gamma promotes brown adipocyte differentiation
-
Tai T-AC, Jennermann C, Brown KK, Oliver BB, MacGinnitie MA, Wilkison WO, Brown HR, Lehmann JM, Kliewer SA, Morris DC and Graves RA (1996) Activation of the nuclear receptor peroxisome proliferator-activated receptor gamma promotes brown adipocyte differentiation. J Biol Chem 271:29909-29914.
-
(1996)
J Biol Chem
, vol.271
, pp. 29909-29914
-
-
Tai, T.-A.C.1
Jennermann, C.2
Brown, K.K.3
Oliver, B.B.4
MacGinnitie, M.A.5
Wilkison, W.O.6
Brown, H.R.7
Lehmann, J.M.8
Kliewer, S.A.9
Morris, D.C.10
Graves, R.A.11
-
18
-
-
0028988487
-
PPAR gamma 2 regulates adipose expression of the phosphoenolpyruvate carboxykinase gene
-
Tontonoz P, Hu E, Devine J, Beale EG and Spiegelman BM (1995) PPAR gamma 2 regulates adipose expression of the phosphoenolpyruvate carboxykinase gene. Mol Cell Biol 15:351-357.
-
(1995)
Mol Cell Biol
, vol.15
, pp. 351-357
-
-
Tontonoz, P.1
Hu, E.2
Devine, J.3
Beale, E.G.4
Spiegelman, B.M.5
-
19
-
-
0030062325
-
Structure-activity relationship between peroxisome proliferator-activated receptor gamma agonism and the antihyperglycemic activity of thiazolidinediones
-
Willson TM, Cobb JE, Cowan DJ, Wiethe RW, Correa ID, Prakash SR, Beck KD, Moore LB, Kliewer SA and Lehmann JM (1996) Structure-activity relationship between peroxisome proliferator-activated receptor gamma agonism and the antihyperglycemic activity of thiazolidinediones. J Med Chem 39:665-668.
-
(1996)
J Med Chem
, vol.39
, pp. 665-668
-
-
Willson, T.M.1
Cobb, J.E.2
Cowan, D.J.3
Wiethe, R.W.4
Correa, I.D.5
Prakash, S.R.6
Beck, K.D.7
Moore, L.B.8
Kliewer, S.A.9
Lehmann, J.M.10
-
20
-
-
14444281382
-
Identification of high-affinity binding sites for the insulin sensitizer rosiglitazone (BRL-49653) in rodent and human adipocytes using a radioiodinated ligand for peroxisomal proliferator-activated receptor gamma
-
Young PW, Buckle DR, Cantello BCC, Chapman H, Clapham JC, Coyle PJ, Haigh D, Hindley RM, Holder JC, Kallender H, Latter AJ, Lawrie KWM, Mossakowska D, Murphy GJ, Roxbee Cox L and Smith SA (1998) Identification of high-affinity binding sites for the insulin sensitizer rosiglitazone (BRL-49653) in rodent and human adipocytes using a radioiodinated ligand for peroxisomal proliferator-activated receptor gamma. J Pharmacol Exp Ther 284: 751-759.
-
(1998)
J Pharmacol Exp Ther
, vol.284
, pp. 751-759
-
-
Young, P.W.1
Buckle, D.R.2
Cantello, B.C.C.3
Chapman, H.4
Clapham, J.C.5
Coyle, P.J.6
Haigh, D.7
Hindley, R.M.8
Holder, J.C.9
Kallender, H.10
Latter, A.J.11
Lawrie, K.W.M.12
Mossakowska, D.13
Murphy, G.J.14
Roxbee Cox, L.15
Smith, S.A.16
|