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Volumn 28, Issue 7, 2000, Pages 772-780

Absorption, disposition, and metabolism of rosiglitazone, a potent thiazolidinedione insulin sensitizer, in humans

Author keywords

[No Author keywords available]

Indexed keywords

DRUG METABOLITE; N DEMETHYLASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; ROSIGLITAZONE;

EID: 0033911580     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (212)

References (20)
  • 2
    • 0029745382 scopus 로고    scopus 로고
    • Thiazolidinediones produce a conformational change in peroxisomal proliferator-activated receptor-γ: Binding and activation correlate with antidiabetic actions in db/db mice
    • Berger J, Bailey P, Biswas C, Cullinan CA, Doebber TW, Hayes NS, Saperstein R, Smith RG and Leibowitz MD (1996) Thiazolidinediones produce a conformational change in peroxisomal proliferator-activated receptor-γ: Binding and activation correlate with antidiabetic actions in db/db mice. Endocrinology 137:4189-4195.
    • (1996) Endocrinology , vol.137 , pp. 4189-4195
    • Berger, J.1    Bailey, P.2    Biswas, C.3    Cullinan, C.A.4    Doebber, T.W.5    Hayes, N.S.6    Saperstein, R.7    Smith, R.G.8    Leibowitz, M.D.9
  • 4
    • 0018155445 scopus 로고
    • Critical evaluation of the potential error in pharmacokinetic studies of using the linear trapezoidal rule method for the calculation of the area under the plasma level-time curve
    • Chiou WL (1978) Critical evaluation of the potential error in pharmacokinetic studies of using the linear trapezoidal rule method for the calculation of the area under the plasma level-time curve. J Pharmacokinet Biopharm 6:539-547.
    • (1978) J Pharmacokinet Biopharm , vol.6 , pp. 539-547
    • Chiou, W.L.1
  • 5
    • 0030462770 scopus 로고    scopus 로고
    • The peroxisome proliferator-activated receptors: Ligand and activators
    • Forman BM, Chen J and Evans RM (1996) The peroxisome proliferator-activated receptors: Ligand and activators. Ann NY Acad Sci 804:266-274.
    • (1996) Ann NY Acad Sci , vol.804 , pp. 266-274
    • Forman, B.M.1    Chen, J.2    Evans, R.M.3
  • 6
    • 0029847076 scopus 로고    scopus 로고
    • Peroxisome proliferator-activaled receptor gamma activation by thiazolidinediones induces adipogenesis in bone marrow stromal cells
    • Gimble JM, Robinson CE, Wu X, Kelly KA, Rodriguez BR, Kliewer SA, Lehmann JM and Morris DC (1996) Peroxisome proliferator-activaled receptor gamma activation by thiazolidinediones induces adipogenesis in bone marrow stromal cells. Mol Pharmacol 50:1087-1094.
    • (1996) Mol Pharmacol , vol.50 , pp. 1087-1094
    • Gimble, J.M.1    Robinson, C.E.2    Wu, X.3    Kelly, K.A.4    Rodriguez, B.R.5    Kliewer, S.A.6    Lehmann, J.M.7    Morris, D.C.8
  • 9
    • 0029016829 scopus 로고
    • An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor γ (PPARγ)
    • Lehmann JM, Moore LB, Smith-Oliver TA, Wilkison WO, Willson TM and Kliewer SA (1995) An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor γ (PPARγ). J Biol Chem 270:12953-12956.
    • (1995) J Biol Chem , vol.270 , pp. 12953-12956
    • Lehmann, J.M.1    Moore, L.B.2    Smith-Oliver, T.A.3    Wilkison, W.O.4    Willson, T.M.5    Kliewer, S.A.6
  • 10
    • 0030658022 scopus 로고    scopus 로고
    • Co-ordinate regulation of the expression of the fatty acid transport protein and acyl-CoA synthetase genes by PPAR alpha and PPAR gamma activators
    • Martin G, Schoonjans K, Lefebvre A-M, Staels B and Auwerx J (1997) Co-ordinate regulation of the expression of the fatty acid transport protein and acyl-CoA synthetase genes by PPAR alpha and PPAR gamma activators. J Biol Chem 272:28210-28217.
    • (1997) J Biol Chem , vol.272 , pp. 28210-28217
    • Martin, G.1    Schoonjans, K.2    Lefebvre, A.-M.3    Staels, B.4    Auwerx, J.5
  • 11
    • 0000224547 scopus 로고    scopus 로고
    • Rosiglitazone decreases insulin resistance and improves beta-cell function in patients with type 2 diabetes
    • Matthews DR, Bakst A, Weston WM and Hemyari P (1999) Rosiglitazone decreases insulin resistance and improves beta-cell function in patients with type 2 diabetes. Diabetologia 42 (Suppl 1):A228.
    • (1999) Diabetologia , vol.42 , Issue.SUPPL. 1
    • Matthews, D.R.1    Bakst, A.2    Weston, W.M.3    Hemyari, P.4
  • 12
    • 0032479423 scopus 로고    scopus 로고
    • Expression of putative fatty acid transporter genes are regulated by peroxisome proliferator-activated receptor alpha and gamma activators in a tissue-and inducer-specific manner
    • Motojima K, Passilly P, Peters JM, Gonzalez FJ and Latruffe N (1998) Expression of putative fatty acid transporter genes are regulated by peroxisome proliferator-activated receptor alpha and gamma activators in a tissue-and inducer-specific manner. J Biol Chem 273:16710-16714.
    • (1998) J Biol Chem , vol.273 , pp. 16710-16714
    • Motojima, K.1    Passilly, P.2    Peters, J.M.3    Gonzalez, F.J.4    Latruffe, N.5
  • 13
    • 0001677801 scopus 로고    scopus 로고
    • Rosiglitazone (BRL49653) monotherapy has significant glucose lowering effect in type 2 diabetic patients
    • Patel J, Miller E, Patwardhan R and Rosiglitazone 011 Study Group (1998) Rosiglitazone (BRL49653) monotherapy has significant glucose lowering effect in type 2 diabetic patients. Diabetes 47 (Suppl 1):A17.
    • (1998) Diabetes , vol.47 , Issue.SUPPL. 1
    • Patel, J.1    Miller, E.2    Patwardhan, R.3
  • 15
    • 0031979733 scopus 로고    scopus 로고
    • Insulin-sensitising agents
    • Perry C and Petrie JR (1998) Insulin-sensitising agents. Emerging Drugs 3:247-260.
    • (1998) Emerging Drugs , vol.3 , pp. 247-260
    • Perry, C.1    Petrie, J.R.2
  • 16
    • 0029791412 scopus 로고    scopus 로고
    • PPAR alpha and PPAR gamma activators direct a distinct tissue-specific transcriptional response via a PPRE in the lipoprotein lipase gene
    • Schoonjans K, Peinado-Onsurbe J, Lefebvre A-M, Heyman RA, Briggs M, Deeb S, Staels B and Auwerx J (1996) PPAR alpha and PPAR gamma activators direct a distinct tissue-specific transcriptional response via a PPRE in the lipoprotein lipase gene. Embo J 15:5336-5348.
    • (1996) Embo J , vol.15 , pp. 5336-5348
    • Schoonjans, K.1    Peinado-Onsurbe, J.2    Lefebvre, A.-M.3    Heyman, R.A.4    Briggs, M.5    Deeb, S.6    Staels, B.7    Auwerx, J.8
  • 18
    • 0028988487 scopus 로고
    • PPAR gamma 2 regulates adipose expression of the phosphoenolpyruvate carboxykinase gene
    • Tontonoz P, Hu E, Devine J, Beale EG and Spiegelman BM (1995) PPAR gamma 2 regulates adipose expression of the phosphoenolpyruvate carboxykinase gene. Mol Cell Biol 15:351-357.
    • (1995) Mol Cell Biol , vol.15 , pp. 351-357
    • Tontonoz, P.1    Hu, E.2    Devine, J.3    Beale, E.G.4    Spiegelman, B.M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.