-
1
-
-
0029161145
-
Famciclovir: A review of its pharmacological properties and therapeutic efficacy in herpesvirus infections
-
C. M. Perry and A. J. Wagstaff: Famciclovir: a review of its pharmacological properties and therapeutic efficacy in herpesvirus infections. Drugs 50, 396-415 (1995).
-
(1995)
Drugs
, vol.50
, pp. 396-415
-
-
Perry, C.M.1
Wagstaff, A.J.2
-
3
-
-
0029946321
-
New antiherpes virus agents
-
F. A. Alrabian and S. L. Sacks: New antiherpes virus agents. Drugs 52, 17-32 (1996).
-
(1996)
Drugs
, vol.52
, pp. 17-32
-
-
Alrabian, F.A.1
Sacks, S.L.2
-
4
-
-
0027133478
-
Pharmacokinetics of famciclovir in man
-
M. A. Pue and L. Z. Benet: Pharmacokinetics of famciclovir in man. Antiviral Chem. Chemother. 4(Suppl. 1), 47-55 (1993).
-
(1993)
Antiviral Chem. Chemother.
, vol.4
, Issue.1 SUPPL.
, pp. 47-55
-
-
Pue, M.A.1
Benet, L.Z.2
-
5
-
-
0029062797
-
Valaciclovir: An improvement over acyclovir for the treatment of zoster
-
A. B. Murray: Valaciclovir: an improvement over acyclovir for the treatment of zoster. Antiviral Chem. Chemother. 6, 34-38 (1995).
-
(1995)
Antiviral Chem. Chemother.
, vol.6
, pp. 34-38
-
-
Murray, A.B.1
-
6
-
-
0024416237
-
Selection of an oral prodrug (BRL 42810; famciclovir) for the antiherpesvirus agent BRL 39123 [9-(4-hydroxy-3-hydroxymethylbut-1-yl)guanine; penciclovir]
-
R. A. Vere Hodge, D. Sutton, M. R. Boyd, M. R. Harnden, and R. L. Jarvest: Selection of an oral prodrug (BRL 42810; famciclovir) for the antiherpesvirus agent BRL 39123 [9-(4-hydroxy-3-hydroxymethylbut-1-yl)guanine; penciclovir]. Antimicrob. Agents Chemother. 33, 1765-1773 (1989).
-
(1989)
Antimicrob. Agents Chemother.
, vol.33
, pp. 1765-1773
-
-
Vere Hodge, R.A.1
Sutton, D.2
Boyd, M.R.3
Harnden, M.R.4
Jarvest, R.L.5
-
7
-
-
0343258430
-
6-Deoxyacyclovir: A xanthine oxidase-activated prodrug of acyclovir
-
T. A. Krenitsky, W. W. Hall, P. de Miranda, L. M. Beauchamp, H. J. Schaeffer, and P. L. Whiteman: 6-Deoxyacyclovir: a xanthine oxidase-activated prodrug of acyclovir. Proc. Natl. Acad. Sci. 81, 3209-3213 (1984).
-
(1984)
Proc. Natl. Acad. Sci.
, vol.81
, pp. 3209-3213
-
-
Krenitsky, T.A.1
Hall, W.W.2
De Miranda, P.3
Beauchamp, L.M.4
Schaeffer, H.J.5
Whiteman, P.L.6
-
8
-
-
0027536616
-
Evidence that famciclovir (BRL 42810) and its associated metabolites do not inhibit the 6β-hydroxylation of testosterone in human liver microsomes
-
A. W. Harrell, S. M. Wheeler, M. Pennick, S. E. Clarke, and R. J. Chenery: Evidence that famciclovir (BRL 42810) and its associated metabolites do not inhibit the 6β-hydroxylation of testosterone in human liver microsomes. Drug Metab. Dispos. 21, 18-23 (1993).
-
(1993)
Drug Metab. Dispos.
, vol.21
, pp. 18-23
-
-
Harrell, A.W.1
Wheeler, S.M.2
Pennick, M.3
Clarke, S.E.4
Chenery, R.J.5
-
9
-
-
0028832926
-
Role of aldehyde oxidase in the in vitro conversion of famciclovir to penciclovir in human liver
-
S. E. Clarke, A. W. Harrell, and R. J. Chenery: Role of aldehyde oxidase in the in vitro conversion of famciclovir to penciclovir in human liver. Drug Metab. Dispos. 23, 251-254 (1995).
-
(1995)
Drug Metab. Dispos.
, vol.23
, pp. 251-254
-
-
Clarke, S.E.1
Harrell, A.W.2
Chenery, R.J.3
-
12
-
-
0016281733
-
A comparison of the distribution and electron acceptor specificities of xanthine oxidase and aldehyde oxidase
-
T. A. Krenitsky, V. Tuttle, E. L. Cattau, and P. Wang: A comparison of the distribution and electron acceptor specificities of xanthine oxidase and aldehyde oxidase. Comp. Biochem. Physiol. 49B, 687-703 (1974).
-
(1974)
Comp. Biochem. Physiol.
, vol.49 B
, pp. 687-703
-
-
Krenitsky, T.A.1
Tuttle, V.2
Cattau, E.L.3
Wang, P.4
-
13
-
-
0023528062
-
Molybdenum hydroxylases: Biological distribution and substrate-inhibitor specificity
-
G. P. Ellis, and G. B. West, Eds., Elsevier, New York
-
C. Beedham: Molybdenum hydroxylases: biological distribution and substrate-inhibitor specificity. In "Progress in Medicinal Chemistry" (G. P. Ellis, and G. B. West, Eds.), Vol. 24, pp. 85-127, Elsevier, New York (1987).
-
(1987)
Progress in Medicinal Chemistry
, vol.24
, pp. 85-127
-
-
Beedham, C.1
-
14
-
-
0023577625
-
Species variation in hepatic aldehyde oxidase activity
-
C. Beedham, S. E. Bruce, D. J. P. Critchley, Y. Al-Tayib, and D. J. Rance: Species variation in hepatic aldehyde oxidase activity. Eur. J. Drug Metab. Pharmacokin. 12, 307-310 (1987).
-
(1987)
Eur. J. Drug Metab. Pharmacokin.
, vol.12
, pp. 307-310
-
-
Beedham, C.1
Bruce, S.E.2
Critchley, D.J.P.3
Al-Tayib, Y.4
Rance, D.J.5
-
15
-
-
0029025709
-
Substrate specificity of human liver aldehyde oxidase towards substituted quinazolines and phthalazines: A comparison with hepatic enzyme from guinea pig, rabbit and baboon
-
C. Beedham, D. J. P. Critchley, and D. J. Rance: Substrate specificity of human liver aldehyde oxidase towards substituted quinazolines and phthalazines: a comparison with hepatic enzyme from guinea pig, rabbit and baboon. Arch. Biochem. Biophys. 319, 481-490 (1995).
-
(1995)
Arch. Biochem. Biophys.
, vol.319
, pp. 481-490
-
-
Beedham, C.1
Critchley, D.J.P.2
Rance, D.J.3
-
16
-
-
0023179545
-
The disposition of 6-deoxyacyclovir: A xanthine oxidase-activated prodrug of acyclovir in the isolated perfused rat liver
-
D. B. Jones, V. K. Rustgi, D. M. Kornhauser, A. Woods, R. Quinn, J. H. Hoofnagle, and A. Jones: The disposition of 6-deoxyacyclovir: a xanthine oxidase-activated prodrug of acyclovir in the isolated perfused rat liver. Hepatology 7, 345-348 (1987).
-
(1987)
Hepatology
, vol.7
, pp. 345-348
-
-
Jones, D.B.1
Rustgi, V.K.2
Kornhauser, D.M.3
Woods, A.4
Quinn, R.5
Hoofnagle, J.H.6
Jones, A.7
-
17
-
-
34547387164
-
Evaluation and metabolism of (-)-6-deoxycarbovir as a prodrug for (-)-carbovir
-
K. R. Iyer: Evaluation and metabolism of (-)-6-deoxycarbovir as a prodrug for (-)-carbovir. Dissertation Abst. Inter. 53, 1313-B (1992).
-
(1992)
Dissertation Abst. Inter.
, vol.53
-
-
Iyer, K.R.1
-
18
-
-
0028230803
-
Use of rat and human in vitro systems to assess the effectiveness and enzymology of deoxyguanine analogs as prodrugs of an antiviral agent
-
A. W. Harrell, S. M. Wheeler, P. East, S. E. Clarke, and R. J. Chenery: Use of rat and human in vitro systems to assess the effectiveness and enzymology of deoxyguanine analogs as prodrugs of an antiviral agent. Drug Metab. Dispos. 22, 189-193 (1994).
-
(1994)
Drug Metab. Dispos.
, vol.22
, pp. 189-193
-
-
Harrell, A.W.1
Wheeler, S.M.2
East, P.3
Clarke, S.E.4
Chenery, R.J.5
-
19
-
-
0021715352
-
Elevation of molybdenum hydroxylase levels in rabbit liver after ingestion of phthalazine or its hydroxylated metabolite
-
C. Johnson, C. Stubley-Beedham, and J. G. P. Stell: Elevation of molybdenum hydroxylase levels in rabbit liver after ingestion of phthalazine or its hydroxylated metabolite. Biochem. Pharmacol. 33, 3699-3705 (1984).
-
(1984)
Biochem. Pharmacol.
, vol.33
, pp. 3699-3705
-
-
Johnson, C.1
Stubley-Beedham, C.2
Stell, J.G.P.3
-
20
-
-
0025266893
-
1-Substituted phthalazines as probes of the substrate-binding site of mammalian molybdenum hydroxylases
-
C. Beedham, S. E. Bruce, D. J. Critchley, and D. J. Rance: 1-Substituted phthalazines as probes of the substrate-binding site of mammalian molybdenum hydroxylases. Biochem. Pharmacol. 39, 1213-1221 (1990).
-
(1990)
Biochem. Pharmacol.
, vol.39
, pp. 1213-1221
-
-
Beedham, C.1
Bruce, S.E.2
Critchley, D.J.3
Rance, D.J.4
-
21
-
-
0001431311
-
Hepatic aldehyde oxidase: I. Purification and properties
-
K. V. Rajagopalan, I. Fridovich, and P. Handler: Hepatic aldehyde oxidase: I. purification and properties. J. Biol. Chem. 237, 922-928 (1962).
-
(1962)
J. Biol. Chem.
, vol.237
, pp. 922-928
-
-
Rajagopalan, K.V.1
Fridovich, I.2
Handler, P.3
-
22
-
-
0022449609
-
Clinical pharmacokinetics of allopurinol
-
G. A. C. Murrell and W. G. Rapeport: Clinical pharmacokinetics of allopurinol. Clin. Pharmacokinet. 11, 343-353 (1986).
-
(1986)
Clin. Pharmacokinet.
, vol.11
, pp. 343-353
-
-
Murrell, G.A.C.1
Rapeport, W.G.2
-
23
-
-
0022186670
-
Measurement of protein using bicinchonic acid
-
P. K. Smith, R. I. Krohn, G. T. Hermanson, A. K. Mallia, F. H. Gartner, M. D. Provenzano, E. K. Fujimoto, N. M. Goeke, B. J. Olson, and C. Klenk: Measurement of protein using bicinchonic acid. Anal. Biochem. 150, 76-85 (1985).
-
(1985)
Anal. Biochem.
, vol.150
, pp. 76-85
-
-
Smith, P.K.1
Krohn, R.I.2
Hermanson, G.T.3
Mallia, A.K.4
Gartner, F.H.5
Provenzano, M.D.6
Fujimoto, E.K.7
Goeke, N.M.8
Olson, B.J.9
Klenk, C.10
-
24
-
-
84985209672
-
Investigation of the substrate-binding site of aldehyde oxidase
-
C. Stubley and J. G. P. Stell: Investigation of the substrate-binding site of aldehyde oxidase. J. Pharm. Pharmacol. 32, 51P (1980).
-
(1980)
J. Pharm. Pharmacol.
, vol.32
-
-
Stubley, C.1
Stell, J.G.P.2
-
25
-
-
0023037533
-
Aldehyde oxidase from rabbit liver: Specificity toward purines and their analogs
-
W. W. Hall and T. A. Krenitsky: Aldehyde oxidase from rabbit liver: specificity toward purines and their analogs. Arch. Biochem. Biophys. 251, 36-46 (1986).
-
(1986)
Arch. Biochem. Biophys.
, vol.251
, pp. 36-46
-
-
Hall, W.W.1
Krenitsky, T.A.2
-
26
-
-
0022545615
-
Xanthine oxidase from human liver: Purification and characterization
-
T. A. Krenitsky, T. Spector, and W. W. Hall: Xanthine oxidase from human liver: purification and characterization. Arch. Biochem. Biophys. 247, 108-119 (1986).
-
(1986)
Arch. Biochem. Biophys.
, vol.247
, pp. 108-119
-
-
Krenitsky, T.A.1
Spector, T.2
Hall, W.W.3
-
27
-
-
0023608778
-
Tissue distribution of the molybdenum hydroxylases, aldehyde oxidase and xanthine oxidase, in male and female guinea pigs
-
C. Beedham, S. E. Bruce, and D. J. Rance: Tissue distribution of the molybdenum hydroxylases, aldehyde oxidase and xanthine oxidase, in male and female guinea pigs. Eur. J. Drug Metab. Pharmacokin. 12, 303-306 (1987).
-
(1987)
Eur. J. Drug Metab. Pharmacokin.
, vol.12
, pp. 303-306
-
-
Beedham, C.1
Bruce, S.E.2
Rance, D.J.3
-
28
-
-
0021876336
-
Analysis of human alcohol-metabolizing and aldehyde-metabolizing isozymes by electrophoresis and isoelectric focusing
-
J. A. Duley, O. Harris, and R. S. Holmes: Analysis of human alcohol-metabolizing and aldehyde-metabolizing isozymes by electrophoresis and isoelectric focusing. Clin. Exp. Res. 9, 263-271 (1985).
-
(1985)
Clin. Exp. Res.
, vol.9
, pp. 263-271
-
-
Duley, J.A.1
Harris, O.2
Holmes, R.S.3
-
29
-
-
0014124340
-
Human liver aldehyde oxidase: Differential inhibition of oxidation of charged and uncharged substrates
-
D. G. Johns: Human liver aldehyde oxidase: differential inhibition of oxidation of charged and uncharged substrates. J. Clin. Invest. 46, 1492-1505 (1967).
-
(1967)
J. Clin. Invest.
, vol.46
, pp. 1492-1505
-
-
Johns, D.G.1
-
32
-
-
0014216473
-
Genetic variations of an oxidase in mammals
-
S. Gluecksohn-Waelsch, P. Greengard, G. P. Quinn, and L. S. Teicher: Genetic variations of an oxidase in mammals. J. Biol. Chem. 242, 1271-1273 (1967).
-
(1967)
J. Biol. Chem.
, vol.242
, pp. 1271-1273
-
-
Gluecksohn-Waelsch, S.1
Greengard, P.2
Quinn, G.P.3
Teicher, L.S.4
-
33
-
-
0021874913
-
Alternate putrescine metabolites: Quantitative analysis of Δ'-pyrroline oxidation to 2-pyrrolidone in tissue homogenates by high pressure liquid chromatography
-
D. W. Lundgren, H. Tevesz, and E. A. Krill: Alternate putrescine metabolites: quantitative analysis of Δ'-pyrroline oxidation to 2-pyrrolidone in tissue homogenates by high pressure liquid chromatography. Anal. Biochem. 148, 461-470 (1985).
-
(1985)
Anal. Biochem.
, vol.148
, pp. 461-470
-
-
Lundgren, D.W.1
Tevesz, H.2
Krill, E.A.3
-
34
-
-
0021763373
-
Simultaneous formation of 2-quinolones and 4-quinolones from quinolinium cations catalyzed by aldehyde oxidase
-
S. M. Taylor, C. Stubley-Beedham, and J. G. P. Stell: Simultaneous formation of 2-quinolones and 4-quinolones from quinolinium cations catalyzed by aldehyde oxidase. Biochem. J. 220, 67-74 (1984).
-
(1984)
Biochem. J.
, vol.220
, pp. 67-74
-
-
Taylor, S.M.1
Stubley-Beedham, C.2
Stell, J.G.P.3
-
35
-
-
0027305791
-
In vitro oxidation of pyrazinamide and allopurinol by rat liver aldehyde oxidase
-
Y. Moriwaki, T. Yamamoto, Y. Nasako, S. Takahashi, M. Suda, K. Hiroishi, T. Hada, and K. Higashino: In vitro oxidation of pyrazinamide and allopurinol by rat liver aldehyde oxidase. Biochem. Pharmacol. 46, 975-981 (1993).
-
(1993)
Biochem. Pharmacol.
, vol.46
, pp. 975-981
-
-
Moriwaki, Y.1
Yamamoto, T.2
Nasako, Y.3
Takahashi, S.4
Suda, M.5
Hiroishi, K.6
Hada, T.7
Higashino, K.8
-
36
-
-
0027143611
-
Drug interaction studies and safety of famciclovir in healthy volunteers: A review
-
S. Daniels and J. J. Schentag: Drug interaction studies and safety of famciclovir in healthy volunteers: a review. Antiviral Chem. Chemother. 4 Suppl 1, 57-64 (1993).
-
(1993)
Antiviral Chem. Chemother.
, vol.4
, Issue.1 SUPPL.
, pp. 57-64
-
-
Daniels, S.1
Schentag, J.J.2
-
37
-
-
0021675922
-
A species-differences in the presystemic metabolism of carbazeran in dog and man
-
B. Kaye, J. L. Offerman, J. L. Reid, H. L. Elliott, and W. S. Willis: A species-differences in the presystemic metabolism of carbazeran in dog and man. Xenobiotica 14, 935-945 (1984).
-
(1984)
Xenobiotica
, vol.14
, pp. 935-945
-
-
Kaye, B.1
Offerman, J.L.2
Reid, J.L.3
Elliott, H.L.4
Willis, W.S.5
-
38
-
-
0021831697
-
Oxidative-metabolism of carbazeran in vitro by liver cytosol of baboon and man
-
B. Kaye, D. J. Rance, and L. Waring: Oxidative-metabolism of carbazeran in vitro by liver cytosol of baboon and man. Xenobiotica 15, 237-242 (1985).
-
(1985)
Xenobiotica
, vol.15
, pp. 237-242
-
-
Kaye, B.1
Rance, D.J.2
Waring, L.3
-
39
-
-
0030772328
-
The role of non-P450 enzymes in drug oxidation
-
C. Beedham: The role of non-P450 enzymes in drug oxidation. Pharm. World Sci., 19, 1-9 (1997).
-
(1997)
Pharm. World Sci.
, vol.19
, pp. 1-9
-
-
Beedham, C.1
|