Ex vivo adenoviral vector-mediated neurotrophin gene transfer to olfactory ensheathing glia: Effects on rubrospinal tract regeneration, lesion size, and functional recovery after implantation in the injured rat spinal cord

Journal of Neuroscience

Volumn 23, Issue 18, 2003, Pages 7045-7058

  Ruitenberg, Marc J ^a   Plant, Giles W ^b,c   Hamers, Frank P T ^d   Wortel, Joke ^a   Blits, Bas ^a   Dijkhuizen, Paul A ^a   Gispen, Willem Hendrik ^d   Boer, Gerard J ^a   Verhaagen, Joost ^a,e  

^a Amsterdam University Medical Center   (Netherlands)

^b UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^c UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^d UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^e NETHERLANDS INSTITUTE FOR NEUROSCIENCE   (Netherlands)

Author keywords

Functional recovery; Gene therapy; Neuroprotection; Olfactory ensheathing glia; Regeneration; Rubrospinal tract; Spinal cord injury; Viral vectors

Indexed keywords

ADENOVIRUS VECTOR; BETA GALACTOSIDASE; BRAIN DERIVED NEUROTROPHIC FACTOR; NEUROTROPHIN 3;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BEHAVIORAL SCIENCE; CONTROLLED STUDY; CONVALESCENCE; CORRELATION ANALYSIS; GENE EXPRESSION; GENE TRANSFER; GENETIC ENGINEERING; GENETIC TRANSDUCTION; GLIA; HINDLIMB; IN VITRO STUDY; LOCOMOTION; NERVE FIBER; NERVE REGENERATION; NEUROFILAMENT; NEUROPROTECTION; NONHUMAN; OLFACTORY NERVE; PRIORITY JOURNAL; RAT; RUBROSPINAL TRACT; SPINAL CORD INJURY; TRANSGENE; TREATMENT OUTCOME; VIRAL GENE THERAPY;

EID: 0043127466     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.23-18-07045.2003     Document Type: Article

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