Axon growth across a lesion site along a preformed guidance pathway in the brain

Experimental Neurology

Volumn 210, Issue 2, 2008, Pages 521-530

  Jin, Ying ^a   Ziemba, Kristine S ^a   Smith, George M ^a  

^a UNIVERSITY OF KENTUCKY   (United States)

Author keywords

Axon growth; Brain injury; Dorsal root ganglion (DRG); Gene therapy; Neurotrophic factors; Transplantation

Indexed keywords

ADENOVIRUS VECTOR; FIBROBLAST GROWTH FACTOR 2; GREEN FLUORESCENT PROTEIN; NERVE GROWTH FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN INJURY; CELL SURVIVAL; CELL SUSPENSION; CELL TRANSPLANTATION; CONTROLLED STUDY; CORPUS CALLOSUM; FEMALE; NERVE FIBER GROWTH; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SPINAL GANGLION; SPRAGUE DAWLEY RAT; TISSUE SECTION;

ADENOVIRIDAE; ANALYSIS OF VARIANCE; ANIMALS; AXONS; BRAIN INJURIES; CORPUS CALLOSUM; DISEASE MODELS, ANIMAL; FEMALE; FIBROBLAST GROWTH FACTOR 2; GANGLIA, SPINAL; GREEN FLUORESCENT PROTEINS; NERVE GROWTH FACTOR; NERVE TISSUE PROTEINS; NEURAL PATHWAYS; NEURONS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 41149088114     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2007.11.030     Document Type: Article

References (49)

1. Bandtlow C.E., and Schwab M.E. NI-35/250/nogo-a: a neurite growth inhibitor restricting structural plasticity and regeneration of nerve fibers in the adult vertebrate CNS. Glia 29 (2000) 175-181
2. Blesch A., Yang H., Weidner N., Hoang A., and Otero D. Axonal responses to cellularly delivered NT-4/5 after spinal cord injury. Mol. Cell. Neurosci. 27 (2004) 190-201
3. Cajal S.R. Cajal's degeneration and regeneration of the nervous system (1928), Oxford University Press, New York
4. Caroni P., and Schwab M.E. Antibody against myelin-associated inhibitor of neurite growth neutralizes non-permissive substrate properties of CNS white matter. Neuron 1 (1988) 85-96
5. Chen Z.J., Ughrin Y., and Levine J.M. Inhibition of axon growth by oligodendrocyte precursor cells. Mol. Cell. Neurosci. 20 (2002) 125-139
6. Davies S.J., Field P.M., and Raisman G. Long interfascicular axon growth from embryonic neurons transplanted into adult myelinated tracts. J. Neurosci. 14 (1994) 1596-1612
7. Davies S.J., Fitch M.T., Memberg S.P., Hall A.K., Raisman G., and Silver J. Regeneration of adult axons in white matter tracts of the central nervous system. Nature 390 (1997) 680-683
8. Davies S.J., Goucher D.R., Doller C., and Silver J. Robust regeneration of adult sensory axons in degenerating white matter of the adult rat spinal cord. J. Neurosci. 19 (1999) 5810-5822
9. de Castro Jr. R., Tajrishi R., Claros J., and Stallcup W.B. Differential responses of spinal axons to transection: influence of the NG2 proteoglycan. Exp. Neurol. 192 (2005) 299-309
10. Fawcett J.W., and Asher R.A. The glial scar and central nervous system repair. Brain Res. Bull. 49 (1999) 377-391
11. Fidler P.S., Schuette K., Asher R.A., Dobbertin A., Thornton S.R., Calle-Patino Y., Muir E., Levine J.M., Geller H.M., Rogers J.H., Faissner A., and Fawcett J.W. Comparing astrocytic cell lines that are inhibitory or permissive for axon growth: the major axon-inhibitory proteoglycan is NG2. J. Neurosci. 19 (1999) 8778-8788
12. Fitch M.T., and Silver J. Glial cell extracellular matrix: boundaries for axon growth in development and regeneration. Cell Tissue Res. 290 (1997) 379-384
13. Gundersen R.W., and Barrett J.N. Characterization of the turning response of dorsal root neurites toward nerve growth factor. J. Cell Biol. 87 (1980) 546-554
14. Horie H., and Akahori Y. Three-dimensional cell aggregation enhances growth-promoting activity of NGF in adult DRG. NeuroReport 6 (1994) 37-40
15. Jakeman L.B., and Reier P.J. Axonal projections between fetal spinal cord transplants and the adult rat spinal cord: a neuroanatomical tracing study of local interactions. J. Comp. Neurol. 307 (1991) 311-334
16. Jin Y., Fischer I., Tessler A., and Houle J.D. Transplants of fibroblasts genetically modified to express BDNF promote axonal regeneration from supraspinal neurons following chronic spinal cord injury. Exp. Neurol. 177 (2002) 265-275
17. Le Gal La Salle G., Robert J.J., Berrard S., Ridoux V., Stratford-Perricaudet L.D., Perricaudet M., and Mallet J. An adenovirus vector for gene transfer into neurons and glia in the brain. Science 259 (1993) 988-990
18. Letourneau P.C. Chemotactic response of nerve fiber elongation to nerve growth factor. Dev. Biol. 66 (1978) 183-196
19. Levi-Montalcini R. Nerve growth factor-target cells. A model of choice in the study of neuron differentiation. Boll. Ist. Sieroter. Milan. 61 (1982) 164-169
20. McDonald J.W., Liu X.Z., Qu Y., Liu S., Mickey S.K., Turetsky D., Gottlieb D.I., and Choi D.W. Transplanted embryonic stem cells survive, differentiate and promote recovery in injured rat spinal cord. Nat. Med. 5 (1999) 1410-1412
21. McKeon R.J., Schreiber R.C., Rudge J.S., and Silver J. Reduction of neurite outgrowth in a model of glial scarring following CNS injury is correlated with the expression of inhibitory molecules on reactive astrocytes. J. Neurosci. 11 (1991) 3398-3411
22. McKerracher L., David S., Jackson D.L., Kottis V., Dunn R.J., and Braun P.E. Identification of myelin-associated glycoprotein as a major myelin-derived inhibitor of neurite growth. Neuron 13 (1994) 805-811
23. Morrison R.S., Sharma A., de Vellis J., and Bradshaw R.A. Basic fibroblast growth factor supports the survival of cerebral cortical neurons in primary culture. Proc. Natl. Acad. Sci. U. S. A. 83 (1986) 7537-7541
24. Mukhopadhyay G., Doherty P., Walsh F.S., Crocker P.R., and Filbin M.T. A novel role for myelin-associated glycoprotein as an inhibitor of axonal regeneration. Neuron 13 (1994) 757-767
25. Ohlsson M., Mattsson P., Wamil B.D., Hellerqvist C.G., and Svensson M. Macrophage stimulation using a group B-streptococcus exotoxin (CM101) leads to axonal regrowth in the injured optic nerve. Restor. Neurol. Neurosci. 22 (2004) 33-41
26. Pettigrew D.B., and Crutcher K.A. White matter of the CNS supports or inhibits neurite outgrowth in vitro depending on geometry. J. Neurosci. 19 (1999) 8358-8366
27. Rhodes K.E., Raivich G., and Fawcett J.W. The injury response of oligodendrocyte precursor cells is induced by platelets, macrophages and inflammation-associated cytokines. Neuroscience 140 (2006) 87-100
28. Romero M.I., Rangappa N., Li L., Lightfoot E., Garry M.G., and Smith G.M. Extensive sprouting of sensory afferents and hyperalgesia induced by conditional expression of nerve growth factor in the adult spinal cord. J. Neurosci. 20 (2000) 4435-4445
29. Romero M.I., Rangappa N., Garry M.G., and Smith G.M. Functional regeneration of chronically injured sensory afferents into adult spinal cord after neurotrophin gene therapy. J. Neurosci. 21 (2001) 8408-8416
30. Santos-Benito F.F., and Ramon-Cueto A. Olfactory ensheathing glia transplantation: a therapy to promote repair in the mammalian central nervous system. Anat. Rec. B New Anat. 271 (2003) 77-85
31. Sapieha P.S., Peltier M., Rendahl K.G., Manning W.C., and Di Polo A. Fibroblast growth factor-2 gene delivery stimulates axon growth by adult retinal ganglion cells after acute optic nerve injury. Mol. Cell. Neurosci. 24 (2003) 656-672
32. Schnell L., and Schwab M.E. Axonal regeneration in the rat spinal cord produced by an antibody against myelin-associated neurite growth inhibitors. Nature 343 (1990) 269-272
33. Shewan D., Berry M., and Cohen J. Extensive regeneration in vitro by early embryonic neurons on immature and adult CNS tissue. J. Neurosci. 15 (1995) 2057-2062
34. Shibata A., Zelivyanskaya M., Limoges J., Carlson K.A., Gorantla S., Branecki C., Bishu S., Xiong H., and Gendelman H.E. Peripheral nerve induces macrophage neurotrophic activities: regulation of neuronal process outgrowth, intracellular signaling and synaptic function. J. Neuroimmunol. 142 (2003) 112-129
35. Silver J., and Miller J.H. Regeneration beyond the glial scar. Nat. Rev., Neurosci. 5 (2004) 146-156
36. Snow D.M., Lemmon V., Carrino D.A., Caplan A.I., and Silver J. Sulfated proteoglycans in astroglial barriers inhibit neurite outgrowth in vitro. Exp. Neurol. 109 (1990) 111-130
37. Sofroniew M.V. Reactive astrocytes in neural repair and protection. Neuroscientist 11 (2005) 400-407
38. Tang X.Q., Tanelian D.L., and Smith G.M. Semaphorin3A inhibits nerve growth factor-induced sprouting of nociceptive afferents in adult rat spinal cord. J. Neurosci. 24 (2004) 819-827
39. Tang X.Q., Heron P., Mashburn C., and Smith G.M. Targeting sensory axon regeneration in adult spinal cord. J. Neurosci. 27 (2007) 6068-6078
40. Taylor L., Jones L., Tuszynski M.H., and Blesch A. Neurotrophin-3 gradients established by lentiviral gene delivery promote short-distance axonal bridging beyond cellular grafts in the injured spinal cord. J. Neurosci. 26 (2006) 9713-9721
41. Tator C.H. Strategies for recovery and regeneration after brain and spinal cord injury. Inj. Prev. 8 Suppl 4 (2002) IV33-IV36
42. Tuszynski M.H., Grill R., Jones L.L., McKay H.M., and Blesch A. Spontaneous and augmented growth of axons in the primate spinal cord: effects of local injury and nerve growth factor-secreting cell grafts. J. Comp. Neurol. 449 (2002) 88-101
43. Varon S., and Conner J.M. Nerve growth factor in CNS repair. J. Neurotrauma 11 (1994) 473-486
44. Wang K.C., Koprivica V., Kim J.A., Sivasankaran R., Guo Y., Neve R.L., and He Z. Oligodendrocyte-myelin glycoprotein is a Nogo receptor ligand that inhibits neurite outgrowth. Nature 417 (2002) 941-944
45. Wictorin K., Clarke D.J., Bolam J.P., and Bjorklund A. Fetal striatal neurons grafted into the ibotenate lesioned adult striatum: efferent projections and synaptic contacts in the host globus pallidus. Neuroscience 37 (1990) 301-315
46. Xu X.M., Guenard V., Kleitman N., and Bunge M.B. Axonal regeneration into Schwann cell-seeded guidance channels grafted into transected adult rat spinal cord. J. Comp. Neurol. 351 (1995) 145-160
47. Yang Z., Suzuki R., Daniels S.B., Brunquell C.B., Sala C.J., and Nishiyama A. NG2 glial cells provide a favorable substrate for growing axons. J. Neurosci. 26 (2006) 3829-3839
48. Ziemba K.S., Chaudhry N., Jin Y., Rabchevshy A.G., and Smith G.M. Targeting axon growth from neuronal transplantation in the adult central nervous system along preformed guidance pathways. J. Neurosci. 28 (2008) 340-348
49. Zuo J., Neubauer D., Graham J., Krekoski C.A., Ferguson T.A., and Muir D. Regeneration of axons after nerve transection repair is enhanced by degradation of chondroitin sulfate proteoglycan. Exp. Neurol. 176 (2002) 221-228