Adeno-associated viral vector-mediated gene transfer of brain-derived neurotrophic factor reverses atrophy of rubrospinal neurons following both acute and chronic spinal cord injury

Neurobiology of Disease

Volumn 15, Issue 2, 2004, Pages 394-406

  Ruitenberg, Marc J ^a   Blits, Bas ^a   Dijkhuizen, Paul A ^a   Te Beek, Erik T ^a   Bakker, Arne ^a   Van Heerikhuize, Joop J ^a   Pool, Chris W ^a   Hermens, Wim T J ^a   Boer, Gerard J ^a   Verhaagen, Joost ^a,b  

^a VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^b NETHERLANDS INSTITUTE FOR NEUROSCIENCE   (Netherlands)

Author keywords

Adeno associated viral vector; Atrophy; Brain derived neurotrophic factor; Gene therapy; Regeneration; Rubrospinal tract; Spinal cord injury

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR; PARVOVIRUS VECTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN ATROPHY; CONTROLLED STUDY; GENE EXPRESSION; GENE THERAPY; GENE TRANSFER; IMMUNOHISTOCHEMISTRY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RED NUCLEUS; RUBROSPINAL TRACT; SPINAL CORD INJURY; TRANSGENE; TREATMENT OUTCOME;

ACUTE DISEASE; ANIMALS; ATROPHY; AXOTOMY; BRAIN-DERIVED NEUROTROPHIC FACTOR; CHRONIC DISEASE; DEPENDOVIRUS; DISEASE MODELS, ANIMAL; EFFERENT PATHWAYS; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; MALE; NERVE REGENERATION; NEURONS; RATS; REACTION TIME; RECEPTOR, TRKB; RED NUCLEUS; RETROGRADE DEGENERATION; SPINAL CORD; SPINAL CORD INJURIES;

EID: 12144288408     PISSN: 09699961     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nbd.2003.11.018     Document Type: Article

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