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Volumn 19, Issue 11, 1999, Pages 4370-4387

Transplants of fibroblasts genetically modified to express BDNF promote regeneration of adult rat rubrospinal axons and recovery of forelimb function

Author keywords

Anterograde tracing; Axon regeneration; Cell transplantation; Neurotrophin; Recovery of function; Retrograde tracing; Retrovirus; Spinal cord injury

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; NEUROTROPHIN;

EID: 0033151593     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.19-11-04370.1999     Document Type: Article
Times cited : (440)

References (84)
  • 1
    • 0027362740 scopus 로고
    • Spinal cord transplants support the regeneration of axotomized neurons after spinal cord lesions at birth: A quantitative double-labeling study
    • Bernstein-Goral H, Bregman BS (1993) Spinal cord transplants support the regeneration of axotomized neurons after spinal cord lesions at birth: a quantitative double-labeling study. Exp Neurol 123:118-132.
    • (1993) Exp Neurol , vol.123 , pp. 118-132
    • Bernstein-Goral, H.1    Bregman, B.S.2
  • 2
    • 0028867947 scopus 로고
    • Recovery from spinal cord injury mediated by antibodies to neurite growth inhibitors
    • Bregman BS, Kunkel-Bagden E, Schnell L, Dai HN, Gao D, Schwab ME (1995) Recovery from spinal cord injury mediated by antibodies to neurite growth inhibitors. Nature 378:498-501.
    • (1995) Nature , vol.378 , pp. 498-501
    • Bregman, B.S.1    Kunkel-Bagden, E.2    Schnell, L.3    Dai, H.N.4    Gao, D.5    Schwab, M.E.6
  • 3
    • 0031427410 scopus 로고    scopus 로고
    • Neurotrophic factors increase axonal growth after spinal cord injury and transplantation in the adult rat
    • Bregman, BS, McAtee M, Dai HN, Kuhn PL (1997) Neurotrophic factors increase axonal growth after spinal cord injury and transplantation in the adult rat. Exp Neurol 148:475-494.
    • (1997) Exp Neurol , vol.148 , pp. 475-494
    • Bregman, B.S.1    McAtee, M.2    Dai, H.N.3    Kuhn, P.L.4
  • 4
    • 1842337453 scopus 로고    scopus 로고
    • Cells of origin, course, and termination patterns of the ventral, uncrossed component of the mature rat corticospinal tract
    • Brosamle C, Schwab ME (1997) Cells of origin, course, and termination patterns of the ventral, uncrossed component of the mature rat corticospinal tract. J Comp Neurol 386:293-303.
    • (1997) J Comp Neurol , vol.386 , pp. 293-303
    • Brosamle, C.1    Schwab, M.E.2
  • 5
    • 0015962920 scopus 로고
    • Rubrospinal projections in the rat
    • Brown LT (1974) Rubrospinal projections in the rat. J Comp Neurol 154:169-187.
    • (1974) J Comp Neurol , vol.154 , pp. 169-187
    • Brown, L.T.1
  • 6
    • 0023967246 scopus 로고
    • Antibody against myelin-associated inhibitor of neurite growth neutralizes nonpermissive substrate properties of CNS white matter
    • Caroni P, Schwab ME (1988) Antibody against myelin-associated inhibitor of neurite growth neutralizes nonpermissive substrate properties of CNS white matter. Neuron 1:85-96.
    • (1988) Neuron , vol.1 , pp. 85-96
    • Caroni, P.1    Schwab, M.E.2
  • 7
    • 0029985953 scopus 로고    scopus 로고
    • Methylprednisolone administration improves axonal regeneration into Schwann cell grafts in transected adult rat thoracic spinal cord
    • Chen A, Xu XM, Kleitman N, Bunge MB (1996) Methylprednisolone administration improves axonal regeneration into Schwann cell grafts in transected adult rat thoracic spinal cord. Exp Neurol 138:261-276.
    • (1996) Exp Neurol , vol.138 , pp. 261-276
    • Chen, A.1    Xu, X.M.2    Kleitman, N.3    Bunge, M.B.4
  • 8
    • 0029840835 scopus 로고    scopus 로고
    • Spinal cord repair in adult paraplegic rats: Partial restoration of hind limb function
    • Cheng H, Cao Y, Olson L (1996) Spinal cord repair in adult paraplegic rats: partial restoration of hind limb function. Science 273:510-513.
    • (1996) Science , vol.273 , pp. 510-513
    • Cheng, H.1    Cao, Y.2    Olson, L.3
  • 10
    • 0019856865 scopus 로고
    • Axonal elongation into peripheral nervous system "bridges" after central nervous system injury in adult rats
    • David S, Aguayo AJ (1981) Axonal elongation into peripheral nervous system "bridges" after central nervous system injury in adult rats. Science 214:931-933.
    • (1981) Science , vol.214 , pp. 931-933
    • David, S.1    Aguayo, A.J.2
  • 11
    • 0027534433 scopus 로고
    • Long fibre growth by axons of embryonic mouse hippocampal neurons microtransplanted into the adult rat fimbria
    • Davies SJ, Field PM, Raisman O (1993) Long fibre growth by axons of embryonic mouse hippocampal neurons microtransplanted into the adult rat fimbria. Eur J Neurosci 5:95-106.
    • (1993) Eur J Neurosci , vol.5 , pp. 95-106
    • Davies, S.J.1    Field, P.M.2    Raisman, O.3
  • 12
    • 0028346532 scopus 로고
    • Long interfascicular axon growth from embryonic neurons transplanted into adult myelinated tracts
    • Davies SJ, Field PM, Raisman G (1994) Long interfascicular axon growth from embryonic neurons transplanted into adult myelinated tracts. J Neurosci 14:1596-1612.
    • (1994) J Neurosci , vol.14 , pp. 1596-1612
    • Davies, S.J.1    Field, P.M.2    Raisman, G.3
  • 13
    • 0031471718 scopus 로고    scopus 로고
    • Regeneration of adult axons in white matter tracts of the central nervous system
    • Davies SJ, Fitch MT, Memberg SP, Hall AK, Raisman G, Silver J (1997) Regeneration of adult axons in white matter tracts of the central nervous system. Nature 390:680-683.
    • (1997) Nature , vol.390 , pp. 680-683
    • Davies, S.J.1    Fitch, M.T.2    Memberg, S.P.3    Hall, A.K.4    Raisman, G.5    Silver, J.6
  • 14
    • 0028286536 scopus 로고
    • Long distance axonal regeneration of identified lamprey reticulospinal neurons
    • Davis Jr GR, McClellan AD (1994) Long distance axonal regeneration of identified lamprey reticulospinal neurons. Exp Neurol 127:94-105.
    • (1994) Exp Neurol , vol.127 , pp. 94-105
    • Davis G.R., Jr.1    McClellan, A.D.2
  • 15
    • 0027965379 scopus 로고
    • Neurotrophic factors prevent the death of CNS neurons after spinal cord lesions in newborn rats
    • Diener PS, Bregman BS (1994) Neurotrophic factors prevent the death of CNS neurons after spinal cord lesions in newborn rats. NeuroReport 5:1913-1917.
    • (1994) Neuroreport , vol.5 , pp. 1913-1917
    • Diener, P.S.1    Bregman, B.S.2
  • 16
    • 0031962067 scopus 로고    scopus 로고
    • Fetal spinal cord transplants support growth of supraspinal and segmental projections after cervical spinal cord hemisection in the neonatal rat
    • Diener PS, Bregman BS (1998) Fetal spinal cord transplants support growth of supraspinal and segmental projections after cervical spinal cord hemisection in the neonatal rat. J Neurosci 18:779-793.
    • (1998) J Neurosci , vol.18 , pp. 779-793
    • Diener, P.S.1    Bregman, B.S.2
  • 17
    • 0032213454 scopus 로고    scopus 로고
    • Regeneration of brainstem-spinal axons after lesion and immunological disruption of myelin in adult rat
    • Dyer JK, Bourque JA, Steeves JD (1998) Regeneration of brainstem-spinal axons after lesion and immunological disruption of myelin in adult rat. Exp Neurol 154:12-22.
    • (1998) Exp Neurol , vol.154 , pp. 12-22
    • Dyer, J.K.1    Bourque, J.A.2    Steeves, J.D.3
  • 19
    • 0025997947 scopus 로고
    • The encephalomyocarditis virus internal ribosome entry site allows efficient coexpression of two genes from a recombinant provirus in cultured cells and in embryos
    • Ghattas IR, Sanes JR, Majors JE (1991) The encephalomyocarditis virus internal ribosome entry site allows efficient coexpression of two genes from a recombinant provirus in cultured cells and in embryos. Mol Cell Biol 11:5848-5859.
    • (1991) Mol Cell Biol , vol.11 , pp. 5848-5859
    • Ghattas, I.R.1    Sanes, J.R.2    Majors, J.E.3
  • 20
    • 16944366150 scopus 로고    scopus 로고
    • Cellular delivery of neurotrophin-3 promotes corticospinal axonal growth and partial functional recovery after spinal cord injury
    • Grill R, Murai K, Blesch A, Gage FH, Tuszynski MH (1997) Cellular delivery of neurotrophin-3 promotes corticospinal axonal growth and partial functional recovery after spinal cord injury. J Neurosci 17:5560-5572.
    • (1997) J Neurosci , vol.17 , pp. 5560-5572
    • Grill, R.1    Murai, K.2    Blesch, A.3    Gage, F.H.4    Tuszynski, M.H.5
  • 21
    • 0028366419 scopus 로고
    • Grafts of fetal central nervous system tissue rescue axotomized Clarke's nucleus neurons in adult and neonatal operates
    • Himes BT, Goldberger ME, Tessler A (1994) Grafts of fetal central nervous system tissue rescue axotomized Clarke's nucleus neurons in adult and neonatal operates. J Comp Neurol 339:117-131.
    • (1994) J Comp Neurol , vol.339 , pp. 117-131
    • Himes, B.T.1    Goldberger, M.E.2    Tessler, A.3
  • 22
    • 0029881407 scopus 로고    scopus 로고
    • Restoration of normal conduction properties in demyelinated spinal cord axons in the adult rat by transplantation of exogenous Schwann cells
    • Honmou O, Felts PA, Waxman SG, Kocsis JD (1996) Restoration of normal conduction properties in demyelinated spinal cord axons in the adult rat by transplantation of exogenous Schwann cells. J Neurosci 16:3199-3208.
    • (1996) J Neurosci , vol.16 , pp. 3199-3208
    • Honmou, O.1    Felts, P.A.2    Waxman, S.G.3    Kocsis, J.D.4
  • 23
    • 0026088477 scopus 로고
    • NGF enhances neurite regeneration from nerve-transected terminals of young adult and aged mouse dorsal root ganglia in vitro
    • Horie H, Bando Y, Chi H, Takenaka T (1991) NGF enhances neurite regeneration from nerve-transected terminals of young adult and aged mouse dorsal root ganglia in vitro. Neurosci Lett 121:125-128.
    • (1991) Neurosci Lett , vol.121 , pp. 125-128
    • Horie, H.1    Bando, Y.2    Chi, H.3    Takenaka, T.4
  • 24
    • 0029793284 scopus 로고    scopus 로고
    • Regenerated dorsal root fibers form functional synapses in embryonic spinal cord transplants
    • Itoh Y, Waldeck RF, Tessler A, Pinter MJ (1996) Regenerated dorsal root fibers form functional synapses in embryonic spinal cord transplants. J Neurophysiol 76:1236-1245.
    • (1996) J Neurophysiol , vol.76 , pp. 1236-1245
    • Itoh, Y.1    Waldeck, R.F.2    Tessler, A.3    Pinter, M.J.4
  • 25
    • 0028079637 scopus 로고
    • Restoration of function by replacement of spinal cord segments in the rat
    • Iwashita Y, Kawaguchi S, Murata M (1994) Restoration of function by replacement of spinal cord segments in the rat. Nature 367:167-170.
    • (1994) Nature , vol.367 , pp. 167-170
    • Iwashita, Y.1    Kawaguchi, S.2    Murata, M.3
  • 27
    • 0032212449 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor stimulates hindlimb stepping and sprouting of cholinergic fibers after spinal cord injury
    • Jakeman LB, Wei P, Guan Z, Stokes BT (1998) Brain-derived neurotrophic factor stimulates hindlimb stepping and sprouting of cholinergic fibers after spinal cord injury. Exp Neurol 154:170-184.
    • (1998) Exp Neurol , vol.154 , pp. 170-184
    • Jakeman, L.B.1    Wei, P.2    Guan, Z.3    Stokes, B.T.4
  • 28
    • 0025146035 scopus 로고
    • Cap-independent translation of encephalomyocarditis virus RNA: Structural elements of the internal ribosomal entry site and involvement of a cellular 57-kD RNA-binding protein
    • Jang SK, Wimmer E (1990) Cap-independent translation of encephalomyocarditis virus RNA: structural elements of the internal ribosomal entry site and involvement of a cellular 57-kD RNA-binding protein. Genes Dev 4:1560-1572.
    • (1990) Genes Dev , vol.4 , pp. 1560-1572
    • Jang, S.K.1    Wimmer, E.2
  • 29
    • 0028296570 scopus 로고
    • Use-dependent growth of pyramidal neurons after neocortical damage
    • Jones, TA, Schallert T (1994) Use-dependent growth of pyramidal neurons after neocortical damage. J Neurosci 14:2140-2152.
    • (1994) J Neurosci , vol.14 , pp. 2140-2152
    • Jones, T.A.1    Schallert, T.2
  • 30
    • 0030747123 scopus 로고    scopus 로고
    • Corticospinal tract regrowth
    • Joosten EA (1997) Corticospinal tract regrowth. Prog Neurobiol 53:1-25.
    • (1997) Prog Neurobiol , vol.53 , pp. 1-25
    • Joosten, E.A.1
  • 31
    • 0026345228 scopus 로고
    • Reactive astrocytes are substrates for the growth of adult CNS axons in the presence of elevated levels of nerve growth factor
    • Kawaja MD, Gage FH (1991) Reactive astrocytes are substrates for the growth of adult CNS axons in the presence of elevated levels of nerve growth factor. Neuron 7:1019-1030.
    • (1991) Neuron , vol.7 , pp. 1019-1030
    • Kawaja, M.D.1    Gage, F.H.2
  • 32
    • 0026723604 scopus 로고
    • Somatic gene transfer of nerve growth factor promotes the survival of axotomized septal neurons and the regeneration of their axons in adult rats
    • Kawaja MD, Rosenberg MB, Yoshida K, Gage FH (1992) Somatic gene transfer of nerve growth factor promotes the survival of axotomized septal neurons and the regeneration of their axons in adult rats. J Neurosci 12:2849-2864.
    • (1992) J Neurosci , vol.12 , pp. 2849-2864
    • Kawaja, M.D.1    Rosenberg, M.B.2    Yoshida, K.3    Gage, F.H.4
  • 33
    • 0026753191 scopus 로고
    • Construction of a bifunctional mRNA in the mouse by using the internal ribosomal entry site of the encephalomyocarditis virus
    • Kim DG, Kang HM, Jang SK, Shin HS (1992) Construction of a bifunctional mRNA in the mouse by using the internal ribosomal entry site of the encephalomyocarditis virus. Mol Cell Biol 12:3636-3643.
    • (1992) Mol Cell Biol , vol.12 , pp. 3636-3643
    • Kim, D.G.1    Kang, H.M.2    Jang, S.K.3    Shin, H.S.4
  • 34
    • 0031467240 scopus 로고    scopus 로고
    • BDNF and NT-4/5 prevent atrophy of rat rubrospinal neurons after cervical axotomy, stimulate GAP-43 and Tα1-tubulin mRNA expression, and promote axonal regeneration
    • Kobayashi NR, Fan DP, Giehl KM, Bedard AM, Wiegand SJ, Tetzlaff W (1997) BDNF and NT-4/5 prevent atrophy of rat rubrospinal neurons after cervical axotomy, stimulate GAP-43 and Tα1-tubulin mRNA expression, and promote axonal regeneration. J Neurosci 17:9583-9595.
    • (1997) J Neurosci , vol.17 , pp. 9583-9595
    • Kobayashi, N.R.1    Fan, D.P.2    Giehl, K.M.3    Bedard, A.M.4    Wiegand, S.J.5    Tetzlaff, W.6
  • 35
    • 0029941372 scopus 로고    scopus 로고
    • Use-dependent exaggeration of neuronal injury following unilateral sensorimotor cortex lesions
    • Kozlowski DA, James DC, Schallert T (1996) Use-dependent exaggeration of neuronal injury following unilateral sensorimotor cortex lesions. J Neurosci 16:4776-4786.
    • (1996) J Neurosci , vol.16 , pp. 4776-4786
    • Kozlowski, D.A.1    James, D.C.2    Schallert, T.3
  • 36
    • 0027444869 scopus 로고
    • Long axon growth from embryonic neurons transplanted into myelinated tracts of the adult rat spinal cord
    • Li Y, Raisman G (1993) Long axon growth from embryonic neurons transplanted into myelinated tracts of the adult rat spinal cord. Brain Res 629:115-127.
    • (1993) Brain Res , vol.629 , pp. 115-127
    • Li, Y.1    Raisman, G.2
  • 37
    • 0030769193 scopus 로고    scopus 로고
    • Repair of adult rat corticospinal tract by transplants of olfactory ensheathing cells
    • Li Y, Field PM, Raisman G (1997) Repair of adult rat corticospinal tract by transplants of olfactory ensheathing cells. Science 277:2000-2002.
    • (1997) Science , vol.277 , pp. 2000-2002
    • Li, Y.1    Field, P.M.2    Raisman, G.3
  • 38
    • 0032535687 scopus 로고    scopus 로고
    • Regeneration of adult rat corticospinal axons induced by transplanted olfactory ensheathing cells
    • Li Y, Field PM, Raisman G (1998) Regeneration of adult rat corticospinal axons induced by transplanted olfactory ensheathing cells. J Neurosci 18:10514-10524.
    • (1998) J Neurosci , vol.18 , pp. 10514-10524
    • Li, Y.1    Field, P.M.2    Raisman, G.3
  • 40
    • 0030778213 scopus 로고    scopus 로고
    • Tau-like proteins in the nervous system of goldfish
    • Liu Y, Xia J, Ma DL, Faber DS, Fischer I (1997b) Tau-like proteins in the nervous system of goldfish. Neurochem Res 22:1511-1516.
    • (1997) Neurochem Res , vol.22 , pp. 1511-1516
    • Liu, Y.1    Xia, J.2    Ma, D.L.3    Faber, D.S.4    Fischer, I.5
  • 42
    • 0020582124 scopus 로고
    • Construction of a retrovirus packaging mutant and its use to produce helper-free defective retrovirus
    • Mann R, Mulligan RC, Baltimore D (1983) Construction of a retrovirus packaging mutant and its use to produce helper-free defective retrovirus. Cell 33:153-159.
    • (1983) Cell , vol.33 , pp. 153-159
    • Mann, R.1    Mulligan, R.C.2    Baltimore, D.3
  • 43
    • 0028917168 scopus 로고
    • Implantation of encapsulated catecholamine and GDNF-producing cells in rats with unilateral dopamine depletions and Parkinsonian symptoms
    • McDermott PE, Frydel B, Ullman MD, Schallert T, Emerich DF (1995) Implantation of encapsulated catecholamine and GDNF-producing cells in rats with unilateral dopamine depletions and Parkinsonian symptoms. Exp Neurol 132:62-76.
    • (1995) Exp Neurol , vol.132 , pp. 62-76
    • McDermott, P.E.1    Frydel, B.2    Ullman, M.D.3    Schallert, T.4    Emerich, D.F.5
  • 44
    • 0032528159 scopus 로고    scopus 로고
    • Neurotrophin-3 and brain-derived neurotrophic factor induce oligodendrocyte proliferation and myelination of regenerating axons in the contused adult rat spinal cord
    • McTigue DM, Horner PJ, Stokes BT, Gage FH (1998) Neurotrophin-3 and brain-derived neurotrophic factor induce oligodendrocyte proliferation and myelination of regenerating axons in the contused adult rat spinal cord. J Neurosci 18:5354-5365.
    • (1998) J Neurosci , vol.18 , pp. 5354-5365
    • McTigue, D.M.1    Horner, P.J.2    Stokes, B.T.3    Gage, F.H.4
  • 45
    • 0031814388 scopus 로고    scopus 로고
    • Schwann cells genetically modified to secrete human BDNF promote enhanced axonal regrowth across transected adult rat spinal cord
    • Menei P, Monteromenei C, Whittemore SR, Bunge RP, Bunge MB (1998) Schwann cells genetically modified to secrete human BDNF promote enhanced axonal regrowth across transected adult rat spinal cord. Eur J Neurosci 10:607-621.
    • (1998) Eur J Neurosci , vol.10 , pp. 607-621
    • Menei, P.1    Monteromenei, C.2    Whittemore, S.R.3    Bunge, R.P.4    Bunge, M.B.5
  • 46
    • 0025398116 scopus 로고
    • Retrovirus packaging cells
    • Miller AD (1990) Retrovirus packaging cells. Hum Gene Ther 1:5-14.
    • (1990) Hum Gene Ther , vol.1 , pp. 5-14
    • Miller, A.D.1
  • 47
    • 0030919912 scopus 로고    scopus 로고
    • Fetal transplants alter the development of function after spinal cord transection in newborn rats
    • Miya D, Giszter S, Mori F, Adipudi V, Tessler A, Murray M (1997) Fetal transplants alter the development of function after spinal cord transection in newborn rats. J Neurosci 17:4856-4872.
    • (1997) J Neurosci , vol.17 , pp. 4856-4872
    • Miya, D.1    Giszter, S.2    Mori, F.3    Adipudi, V.4    Tessler, A.5    Murray, M.6
  • 48
    • 0026588638 scopus 로고
    • Retroviral vectors containing putative internal ribosome entry sites: Development of a polycistronic gene transfer system and applications to human gene therapy
    • Morgan RA, Couture L, Elroy-Stein O, Ragheb J, Moss B, Anderson WF (1992) Retroviral vectors containing putative internal ribosome entry sites: development of a polycistronic gene transfer system and applications to human gene therapy. Nucleic Acids Res 20:1293-1299.
    • (1992) Nucleic Acids Res , vol.20 , pp. 1293-1299
    • Morgan, R.A.1    Couture, L.2    Elroy-Stein, O.3    Ragheb, J.4    Moss, B.5    Anderson, W.F.6
  • 49
    • 0031036301 scopus 로고    scopus 로고
    • Fetal spinal cord transplants rescue some axotomized rubrospinal neurons from retrograde cell death in adult rats
    • Mori F, Himes BT, Kowada M, Murray M, Tessler A (1997) Fetal spinal cord transplants rescue some axotomized rubrospinal neurons from retrograde cell death in adult rats. Exp Neurol 143:45-60.
    • (1997) Exp Neurol , vol.143 , pp. 45-60
    • Mori, F.1    Himes, B.T.2    Kowada, M.3    Murray, M.4    Tessler, A.5
  • 50
    • 0027474188 scopus 로고
    • Differential regenerative growth of CNS axons into tibial and peroneal nerve grafts in the thalamus of adult rats
    • Morrow DR, Campbell G, Lieberman AR, Anderson PN (1993) Differential regenerative growth of CNS axons into tibial and peroneal nerve grafts in the thalamus of adult rats. Exp Neurol 120:60-69.
    • (1993) Exp Neurol , vol.120 , pp. 60-69
    • Morrow, D.R.1    Campbell, G.2    Lieberman, A.R.3    Anderson, P.N.4
  • 51
    • 0029983422 scopus 로고    scopus 로고
    • Grafts of fibroblasts genetically modified to secrete NGF, BDNF, NT-3, or basic FGF elicit differential responses in the adult spinal cord
    • Nakahara Y, Gage FH, Tuszynski MH (1996) Grafts of fibroblasts genetically modified to secrete NGF, BDNF, NT-3, or basic FGF elicit differential responses in the adult spinal cord. Cell Transplant 5:191-204.
    • (1996) Cell Transplant , vol.5 , pp. 191-204
    • Nakahara, Y.1    Gage, F.H.2    Tuszynski, M.H.3
  • 52
    • 0030596134 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor reduces necrotic zone and supports neuronal survival after spinal cord hemisection in adult rats
    • Novikova L, Novikov L, Kellerth JO (1996) Brain-derived neurotrophic factor reduces necrotic zone and supports neuronal survival after spinal cord hemisection in adult rats. Neurosci Lett 220:203-206.
    • (1996) Neurosci Lett , vol.220 , pp. 203-206
    • Novikova, L.1    Novikov, L.2    Kellerth, J.O.3
  • 53
    • 0030222129 scopus 로고    scopus 로고
    • Nerve growth factor promotes regeneration of sensory axons into adult rat spinal cord
    • Oudega M, Hagg T (1996) Nerve growth factor promotes regeneration of sensory axons into adult rat spinal cord. Exp Neurol 140:218-229.
    • (1996) Exp Neurol , vol.140 , pp. 218-229
    • Oudega, M.1    Hagg, T.2
  • 54
    • 0031427380 scopus 로고    scopus 로고
    • Activated macrophage/microglial cells can promote the regeneration of sensory axons into the injured spinal cord
    • Prewitt CM, Niesman IR, Kane CJ, Houle JD (1997) Activated macrophage/microglial cells can promote the regeneration of sensory axons into the injured spinal cord. Exp Neurol 148:433-443.
    • (1997) Exp Neurol , vol.148 , pp. 433-443
    • Prewitt, C.M.1    Niesman, I.R.2    Kane, C.J.3    Houle, J.D.4
  • 55
    • 0031022698 scopus 로고    scopus 로고
    • Grafting of cultured microglial cells into the lesioned spinal cord of adult rats enhances neurite outgrowth
    • Rabchevsky AG, Streit WJ (1997) Grafting of cultured microglial cells into the lesioned spinal cord of adult rats enhances neurite outgrowth. J Neurosci Res 47:34-48.
    • (1997) J Neurosci Res , vol.47 , pp. 34-48
    • Rabchevsky, A.G.1    Streit, W.J.2
  • 56
    • 0020040379 scopus 로고
    • Peripheral nerve autografts to the rat spinal cord: Studies with axonal tracing methods
    • Richardson PM, McGuinness UM, Aguayo AJ (1982) Peripheral nerve autografts to the rat spinal cord: studies with axonal tracing methods. Brain Res 237:147-162.
    • (1982) Brain Res , vol.237 , pp. 147-162
    • Richardson, P.M.1    McGuinness, U.M.2    Aguayo, A.J.3
  • 59
    • 0025277372 scopus 로고
    • Lesioned corticospinal tract axons regenerate in myelin-free rat spinal cord
    • Savio T, Schwab ME (1990) Lesioned corticospinal tract axons regenerate in myelin-free rat spinal cord. Proc Natl Acad Sci USA 87:4130-4133.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 4130-4133
    • Savio, T.1    Schwab, M.E.2
  • 60
    • 0027818826 scopus 로고
    • "Exuberant" neuronal growth after brain damage in adult rats: The essential role of behavioral experience
    • Schallert T, Jones TA (1993) "Exuberant" neuronal growth after brain damage in adult rats: the essential role of behavioral experience. J Neural Transplant Plast 4:193-198.
    • (1993) J Neural Transplant Plast , vol.4 , pp. 193-198
    • Schallert, T.1    Jones, T.A.2
  • 61
    • 0000863296 scopus 로고    scopus 로고
    • Brain damage and plasticity: Use-related enhanced neural growth and overuse-related exaggeration of injury
    • (Ginsberg MD, Bogousslavsky J, eds), New York: Blackwell Science
    • Schallert T, Kozlowski DA (1998) Brain damage and plasticity: use-related enhanced neural growth and overuse-related exaggeration of injury. In: Cerebrovascular disease (Ginsberg MD, Bogousslavsky J, eds), pp 611-619. New York: Blackwell Science.
    • (1998) Cerebrovascular Disease , pp. 611-619
    • Schallert, T.1    Kozlowski, D.A.2
  • 62
    • 0025440376 scopus 로고
    • Rescuing neurons from trans-synaptic degeneration after brain damage: Helpful, harmful or neutral in recovery of function?
    • Schallert T, Lindner MD (1990) Rescuing neurons from trans-synaptic degeneration after brain damage: helpful, harmful or neutral in recovery of function? Can J Psychol 44:276-292.
    • (1990) Can J Psychol , vol.44 , pp. 276-292
    • Schallert, T.1    Lindner, M.D.2
  • 63
    • 0025017637 scopus 로고
    • Axonal regeneration in the rat spinal cord produced by an antibody against myelin-associated neurite growth inhibitors
    • Schnell L, Schwab ME (1990) Axonal regeneration in the rat spinal cord produced by an antibody against myelin-associated neurite growth inhibitors. Nature 343:269-272.
    • (1990) Nature , vol.343 , pp. 269-272
    • Schnell, L.1    Schwab, M.E.2
  • 64
    • 0027213847 scopus 로고
    • Sprouting and regeneration of lesioned corticospinal tract fibres in the adult rat spinal cord
    • Schnell L, Schwab ME (1993) Sprouting and regeneration of lesioned corticospinal tract fibres in the adult rat spinal cord. Eur J Neurosci 5:1156-1171.
    • (1993) Eur J Neurosci , vol.5 , pp. 1156-1171
    • Schnell, L.1    Schwab, M.E.2
  • 65
    • 0028115777 scopus 로고
    • Neurotrophin-3 enhances sprouting of corticospinal tract during development and after adult spinal cord lesion
    • Schnell L, Schneider R, Kolbeck R, Barde YA, Schwab ME (1994) Neurotrophin-3 enhances sprouting of corticospinal tract during development and after adult spinal cord lesion. Nature 367:170-173.
    • (1994) Nature , vol.367 , pp. 170-173
    • Schnell, L.1    Schneider, R.2    Kolbeck, R.3    Barde, Y.A.4    Schwab, M.E.5
  • 66
    • 0029900303 scopus 로고    scopus 로고
    • Degeneration and regeneration of axons in the lesioned spinal cord
    • Schwab ME, Bartholdi D (1996) Degeneration and regeneration of axons in the lesioned spinal cord. Physiol Rev 76:319-370.
    • (1996) Physiol Rev , vol.76 , pp. 319-370
    • Schwab, M.E.1    Bartholdi, D.2
  • 67
    • 0031882383 scopus 로고    scopus 로고
    • Neurotrophin-3 prevents death of axotomized Clarkes nucleus neurons in adult rat
    • Shibayama M, Hattori S, Himes BT, Murray M, Tessler A (1998) Neurotrophin-3 prevents death of axotomized Clarkes nucleus neurons in adult rat. J Comp Neurol 390:102-111.
    • (1998) J Comp Neurol , vol.390 , pp. 102-111
    • Shibayama, M.1    Hattori, S.2    Himes, B.T.3    Murray, M.4    Tessler, A.5
  • 68
    • 0030779097 scopus 로고    scopus 로고
    • The use of nonneuronal cells for gene delivery
    • Snyder EY, Senut MC (1997) The use of nonneuronal cells for gene delivery. Neurobiol Dis 4:69-102.
    • (1997) Neurobiol Dis , vol.4 , pp. 69-102
    • Snyder, E.Y.1    Senut, M.C.2
  • 69
    • 0345195968 scopus 로고    scopus 로고
    • Experimental strategies to promote axonal regeneration after traumatic central nervous system injury
    • Stichel CC, Muller HW (1998) Experimental strategies to promote axonal regeneration after traumatic central nervous system injury. Prog Neurobiol 56:119-148.
    • (1998) Prog Neurobiol , vol.56 , pp. 119-148
    • Stichel, C.C.1    Muller, H.W.2
  • 70
    • 0031817692 scopus 로고    scopus 로고
    • Spinal cord injury in the rat
    • Taoka Y, Okajima K (1998) Spinal cord injury in the rat. Prog Neurobiol 56:341-358.
    • (1998) Prog Neurobiol , vol.56 , pp. 341-358
    • Taoka, Y.1    Okajima, K.2
  • 73
    • 0000340743 scopus 로고
    • Ascending and descending pathways in the spinal cord
    • (Paxinos G, ed.), San Diego: Academic
    • Tracey DJ (1995) Ascending and descending pathways in the spinal cord. In: The rat nervous system, Ed 2 (Paxinos G, ed.), pp 67-80. San Diego: Academic.
    • (1995) The Rat Nervous System, Ed 2 , pp. 67-80
    • Tracey, D.J.1
  • 74
    • 0028218083 scopus 로고
    • Fibroblasts genetically modified to produce nerve growth factor induce robust neuritic ingrowth after grafting to the spinal cord
    • Tuszynski MH, Peterson DA, Ray J, Baird A, Nakahara Y, Gage FH (1994) Fibroblasts genetically modified to produce nerve growth factor induce robust neuritic ingrowth after grafting to the spinal cord. Exp Neurol 126:1-14.
    • (1994) Exp Neurol , vol.126 , pp. 1-14
    • Tuszynski, M.H.1    Peterson, D.A.2    Ray, J.3    Baird, A.4    Nakahara, Y.5    Gage, F.H.6
  • 75
    • 0014594221 scopus 로고
    • Descending nerve tracts in the spinal cord of the rat. I. Fibers from the midbrain
    • Waldron HA, Gwyn DG (1969) Descending nerve tracts in the spinal cord of the rat. I. Fibers from the midbrain. J Comp Neurol 137:143-153.
    • (1969) J Comp Neurol , vol.137 , pp. 143-153
    • Waldron, H.A.1    Gwyn, D.G.2
  • 76
    • 0030079438 scopus 로고    scopus 로고
    • Physiological relevance and functional potential of central nervous system-derived cell lines
    • Whittemore SR, Snyder EY (1996) Physiological relevance and functional potential of central nervous system-derived cell lines. Mol Neurobiol 12:13-38.
    • (1996) Mol Neurobiol , vol.12 , pp. 13-38
    • Whittemore, S.R.1    Snyder, E.Y.2
  • 77
    • 0027076692 scopus 로고
    • Axon outgrowth from grafts of human embryonic spinal cord in the lesioned adult rat spinal cord
    • Wictorin K, Bjorklund A (1992) Axon outgrowth from grafts of human embryonic spinal cord in the lesioned adult rat spinal cord. NeuroReport 3:1045-1048.
    • (1992) NeuroReport , vol.3 , pp. 1045-1048
    • Wictorin, K.1    Bjorklund, A.2
  • 78
    • 0025147417 scopus 로고
    • Reformation of long axon pathways in adult rat central nervous system by human forebrain neuroblasts
    • Wictorin K, Brundin P, Gustavii B, Lindvall O, Bjorklund A (1990a) Reformation of long axon pathways in adult rat central nervous system by human forebrain neuroblasts. Nature 347:556-558.
    • (1990) Nature , vol.347 , pp. 556-558
    • Wictorin, K.1    Brundin, P.2    Gustavii, B.3    Lindvall, O.4    Bjorklund, A.5
  • 79
    • 0025032666 scopus 로고
    • Extensive efferent projections of intra-striatally transplanted striatal neurons as revealed by a species-specific neurofilament marker and anterograde axonal tracing
    • Wictorin K, Clarke DJ, Bolam JP, Brundin P, Gustavii B, Lindvall O, Bjorklund A (1990b) Extensive efferent projections of intra-striatally transplanted striatal neurons as revealed by a species-specific neurofilament marker and anterograde axonal tracing. Prog Brain Res 82:391-399.
    • (1990) Prog Brain Res , vol.82 , pp. 391-399
    • Wictorin, K.1    Clarke, D.J.2    Bolam, J.P.3    Brundin, P.4    Gustavii, B.5    Lindvall, O.6    Bjorklund, A.7
  • 80
    • 0026701417 scopus 로고
    • Long distance directed axonal growth from human dopaminergic mesencephalic neuroblasts implanted along the nigrostriatal pathway in 6-hydroxydopamine lesioned adult rats
    • Wictorin K, Brundin P, Sauer H, Lindvall O, Bjorklund A (1992) Long distance directed axonal growth from human dopaminergic mesencephalic neuroblasts implanted along the nigrostriatal pathway in 6-hydroxydopamine lesioned adult rats. J Comp Neurol 323:475-494.
    • (1992) J Comp Neurol , vol.323 , pp. 475-494
    • Wictorin, K.1    Brundin, P.2    Sauer, H.3    Lindvall, O.4    Bjorklund, A.5
  • 81
    • 0028874907 scopus 로고
    • A combination of BDNF and NT-3 promotes supraspinal axonal regeneration into Schwann cell grafts in adult rat thoracic spinal cord
    • Xu XM, Guenard V, Kleitman N, Aebischer P, Bunge MB (1995a) A combination of BDNF and NT-3 promotes supraspinal axonal regeneration into Schwann cell grafts in adult rat thoracic spinal cord. Exp Neurol 134:261-272.
    • (1995) Exp Neurol , vol.134 , pp. 261-272
    • Xu, X.M.1    Guenard, V.2    Kleitman, N.3    Aebischer, P.4    Bunge, M.B.5
  • 82
    • 0028870347 scopus 로고
    • Axonal regeneration into Schwann cell-seeded guidance channels grafted into transected adult rat spinal cord
    • Xu XM, Guenard V, Kleitman N, Bunge MB (1995b) Axonal regeneration into Schwann cell-seeded guidance channels grafted into transected adult rat spinal cord. J Comp Neurol 351:145-160.
    • (1995) J Comp Neurol , vol.351 , pp. 145-160
    • Xu, X.M.1    Guenard, V.2    Kleitman, N.3    Bunge, M.B.4
  • 83
    • 0031013730 scopus 로고    scopus 로고
    • Treatment of the chronically injured spinal cord with neurotrophic factors can promote axonal regeneration from supraspinal neurons
    • Ye JH, Houle JD (1997) Treatment of the chronically injured spinal cord with neurotrophic factors can promote axonal regeneration from supraspinal neurons. Exp Neurol 143:70-81.
    • (1997) Exp Neurol , vol.143 , pp. 70-81
    • Ye, J.H.1    Houle, J.D.2
  • 84
    • 0032526742 scopus 로고    scopus 로고
    • Functional recovery and enhanced corticofugal plasticity after unilateral pyramidal tract lesion and blockade of myelin-associated neurite growth inhibitors in adult rats
    • Z'Graggen WJ, Metz GAS, Kartje GL, Thallmair M, Schwab ME (1998) Functional recovery and enhanced corticofugal plasticity after unilateral pyramidal tract lesion and blockade of myelin-associated neurite growth inhibitors in adult rats. J Neurosci 18:4744-4757.
    • (1998) J Neurosci , vol.18 , pp. 4744-4757
    • Z'Graggen, W.J.1    Metz, G.A.S.2    Kartje, G.L.3    Thallmair, M.4    Schwab, M.E.5


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