Neurotrophins BDNF and NT-3 promote axonal re-entry into the distal host spinal cord through Schwann cell-seeded mini-channels

European Journal of Neuroscience

Volumn 13, Issue 2, 2001, Pages 257-268

  Bamber, Norman I ^a   Li, Huaying ^a   Lu, Xiaobin ^a   Oudega, Martin ^b   Aebischer, Patrick ^c   Xu, Xiao Ming ^a  

^a SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MIAMI   (United States)

^c LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

Author keywords

Rat; Regeneration; Spinal cord injury; Transplantation

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; CELL MARKER; NEUROTROPHIN;

ARTICLE; ASTROCYTE; INFUSION; MYELINATION; NERVE FIBER DEGENERATION; PRIORITY JOURNAL; SCHWANN CELL; SPINAL CORD;

ANIMALS; AXONS; BRAIN-DERIVED NEUROTROPHIC FACTOR; FEMALE; INFUSION PUMPS, IMPLANTABLE; MICROSCOPY, ELECTRON; NERVE REGENERATION; NEUROTROPHIN 3; RATS; RATS, INBRED F344; SCHWANN CELLS; SPINAL CORD INJURIES;

EID: 0035122596     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1460-9568.2001.01387.x     Document Type: Article

References (51)

1. Neurotrophin-3 prevents the death of adult central noradrenergic neurons in vivo
2. Fetal spinal cord tissue in mini-guidance channels promotes longitudinal axonal growth after grafting into hemisected adult rat spinal cords
3. The trk family of neurotrophin receptors
4. Graded histological and locomotor outcomes after spinal cord contusion using the NYU weight-drop device versus transection
5. Neurotrophic factors increase axonal growth after spinal cord injury and transplantation in the adult rat
6. Observations on the pathology of human spinal cord injury. A review and classification of 22 new cases with details from a case of chronic cord compression with extensive focal demyelination
7. A potent inhibitor of neurite outgrowth that predominates in the extracellular matrix of reactive astrocytes
8. Spinal cord repair in adult paraplegic rats: Partial restoration of hind limb function
9. Neurotrophins and their trk receptors in cultured cells of the glial lineage and in white matter of the central nervous system
10. Neurotrophic factors prevent the death of CNS neurons after spinal cord lesions in newborn rats
11. Subventricular zone astrocytes are neural stem cells in the adult mammalian brain
12. Neurotrophins and their receptors in nerve injury and repair
13. An anterograde neuroanatomical tracing method that shows the detailed morphology of neurons, their axons and terminals: Immunohistochemical localization of an axonally transported plant lectin. Phaseolus vulgaris leucoagglutinin (PHA-L)
14. BDNF and NT-3, but not NGF, prevent axotomy-induced death of rat corticospinal neurons in vivo
15. Cellular delivery of neurotrophin-3 promotes corticospinal axonal growth and partial functional recovery after spinal cord injury
16. Inhibition of sensory neuron apoptosis and prevention of loss by NT-3 administration following axotomy
17. The use of Schwann cell transplantation to foster central nervous system repair
18. Nerve growth factor infusion into the denervated adult rat hippocampal formation promotes its cholinergic reinnervation
19. Astroglia in CNS injury
20. A comparative study of the immunohistochemical localization of a presumptive proctolin-like peptide, thyrotropin-releasing hormone and 5-hydroxytryptamine in the rat central nervous system
21. Collagen containing neurtrophin-3 (NT-3) attracts regrowing injured corticospinal axons in the adult rat spinal cord and promotes partial functional recovery
22. Local application of collagen containing brain-derived neurotrophic factor decreases the loss of function after spinal cord injury in the adult rat
23. Brain-derived neurotrophic factor stimulates hindlimb stepping and sprouting of cholinergic fibers after spinal cord injury
24. Treatment with genetically engineered fibroblasts producing NGF or BDNF can accelerate recovery from traumatic spinal cord injury in the adult rat
25. Neuronal and glial apoptosis after traumatic spinal cord injury
26. Injury-induced proteoglycans inhibit the potential for laminin-mediated axon growth on astrocytic scars
27. Neurotrophin-3 and brain derived neurotrophic factor induce oligodendrocyte proliferation and myelination of regenerating axons in the contused adult rat spinal cord
28. Isolation and functional characterization of Schwann cells derived from adult peripheral nerve
29. Grafts of fibroblasts genetically modified to secrete NGF, BDNF, NT-3 or basic FGF elicit differential responses in the adult spinal cord
30. Nerve growth factor promotes regeneration of sensory axons into adult rat spinal cord
31. Neurotrophins promote regeneration of sensory axons in the adult rat spinal cord
32. The glial scar: Its bearing on axonal elongation and transplantation approaches to CNS repair
33. Axons from CNS neurones regenerate into PNS grafts
34. Neurotrophin-3 enhances sprouting of corticospinal tract during development and after adult spinal cord lesion
35. Sprouting and regeneration of lesioned corticospinal tract fibers in the adult rat spinal cord
36. Myelin-associated inhibitors of neurite growth
37. Degeneration and regeneration of axons in the lesioned spinal cord
38. Functions of the neurotrophins during nervous system development: What the knockouts are teaching us
39. Glial swelling and astrogliosis produce diffusion barriers in the rat spinal cord
40. Response of rubrospinal and corticospinal neurons to injury and neurotrophins
41. Trk A, B, and C are commonly expressed in human astrocytes and astrocytic gliomas but not by human oligodendrocytes and oligodendroglioma
42. A small-gauge cannula device for continuous infusion of exogenous agents into the brain
43. Anterograde neuroanatomical tracing with phaseolus vulgaris-leucoagglutinin combined with immunocytochemistry of gammaamino butyric acid, choline acetyltransferase or serotonin
44. Projections of the prefrontal cortex to histaminergic cell groups in the posterior hypothalamic region of the rat. Anterograde tracing with phaseolus vulgaris-leucoagglutinin combined with immunocytochemistry of histidine decarboxylase
45. Bridging Schwann cell transplants promote axonal regeneration from both the rostral and caudal stumps of transected adult rat spinal cord
46. A combination of BDNF and NT-3 promotes supraspinal axonal regeneration into Schwann cell grafts in adult rat throracic spinal cord
47. Axonal regeneration into Schwann cell-seeded guidance channels grafted into transected adult rat spinal cord
48. Regrowth of axons into the distal spinal cord through a Schwann cell-seeded minichannel implanted into hemisected adult rat spinal cord
49. Treatment of the chronically injured spinal cord with neurotrophic factors can promote axonal regeneration from supraspinal neurons
50. Secondary injury mechanisms in acute spinal cord injury
51. Ventral striatopallidothalamic projection: IV. Relative involvements of neurochemically distinct subterritories in the ventral pallidum and adjacent parts of the rostroventral forebrain