-
1
-
-
0025932984
-
Apoptosis: mechanisms and roles in pathology
-
Arends, M.J. and Wyllie, A.H. (1991) Apoptosis: mechanisms and roles in pathology. Int. Rev. Exp. Pathol., 32, 223-254.
-
(1991)
Int. Rev. Exp. Pathol.
, vol.32
, pp. 223-254
-
-
Arends, M.J.1
Wyllie, A.H.2
-
2
-
-
0025719085
-
Mechanisms and functions of cell death
-
Ellis, R.E., Yuan, J.Y. and Horvitz, H.R. (1991) Mechanisms and functions of cell death. Annu. Rev. Cell Biol., 7, 663-698.
-
(1991)
Annu. Rev. Cell Biol.
, vol.7
, pp. 663-698
-
-
Ellis, R.E.1
Yuan, J.Y.2
Horvitz, H.R.3
-
3
-
-
0033614903
-
Apoptosis. All's well that ends dead
-
Zheng, T.S. and Flavell, R.A. (1999) Apoptosis. All's well that ends dead. Nature, 400, 410-411.
-
(1999)
Nature
, vol.400
, pp. 410-411
-
-
Zheng, T.S.1
Flavell, R.A.2
-
4
-
-
0032777272
-
Caspase knockouts: matters of life and death
-
Zheng, T.S., Hunot, S., Kuida, K. and Flavell, R.A. (1999) Caspase knockouts: matters of life and death. Cell Death Differ., 6, 1043-1053.
-
(1999)
Cell Death Differ.
, vol.6
, pp. 1043-1053
-
-
Zheng, T.S.1
Hunot, S.2
Kuida, K.3
Flavell, R.A.4
-
5
-
-
0027373764
-
Programmed cell death and the control of cell survival: lessons from the nervous system
-
Raff, M.C., Barres, B.A., Burne, J.F., Coles, H.S., Ishizaki, Y. and Jacobson, M.D. (1993) Programmed cell death and the control of cell survival: lessons from the nervous system. Science, 262, 695-700.
-
(1993)
Science
, vol.262
, pp. 695-700
-
-
Raff, M.C.1
Barres, B.A.2
Burne, J.F.3
Coles, H.S.4
Ishizaki, Y.5
Jacobson, M.D.6
-
7
-
-
0033619265
-
Negative regulation of erythropoiesis by caspase-mediated cleavage of GATA-1
-
De Maria, R., Zeuner, A., Eramo, A., Domenichelli, C., Bonci, D., Grignani, F., Srinivasula, S.M., Alnemri, E.S., Testa, U. and Peschle, C. (1999) Negative regulation of erythropoiesis by caspase-mediated cleavage of GATA-1. Nature, 401, 489-493.
-
(1999)
Nature
, vol.401
, pp. 489-493
-
-
De Maria, R.1
Zeuner, A.2
Eramo, A.3
Domenichelli, C.4
Bonci, D.5
Grignani, F.6
Srinivasula, S.M.7
Alnemri, E.S.8
Testa, U.9
Peschle, C.10
-
8
-
-
0033386808
-
Caspase activation is required for T cell proliferation
-
Kennedy, N., Kataoka, T., Tschopp, J. and Budd, R.C. (1999) Caspase activation is required for T cell proliferation. J. Exp. Med., 190, 1725-1728.
-
(1999)
J. Exp. Med.
, vol.190
, pp. 1725-1728
-
-
Kennedy, N.1
Kataoka, T.2
Tschopp, J.3
Budd, R.C.4
-
9
-
-
77953271477
-
Caspase-3 activation via mitochondria is required for long-term depression and AMPA receptor internalization
-
Li, Z., Jo, J., Jia, J.-M., Lo, S.-C., Whitcomb, D.J., Jiao, S., Cho, K. and Sheng, M. (2010) Caspase-3 activation via mitochondria is required for long-term depression and AMPA receptor internalization. Cell, 141, 859-871.
-
(2010)
Cell
, vol.141
, pp. 859-871
-
-
Li, Z.1
Jo, J.2
Jia, J.-M.3
Lo, S.-C.4
Whitcomb, D.J.5
Jiao, S.6
Cho, K.7
Sheng, M.8
-
10
-
-
0242432345
-
Many cuts to ruin: a comprehensive update of caspase substrates
-
Fischer, U., Jänicke, R.U. and Schulze-Osthoff, K. (2003) Many cuts to ruin: a comprehensive update of caspase substrates. Cell Death Differ., 10, 76-100.
-
(2003)
Cell Death Differ
, vol.10
, pp. 76-100
-
-
Fischer, U.1
Jänicke, R.U.2
Schulze-Osthoff, K.3
-
11
-
-
0034699033
-
Caspase activity plays an essential role in long-term memory
-
Dash, P.K., Blum, S. and Moore, A.N. (2000) Caspase activity plays an essential role in long-term memory. Neuroreport, 11, 2811-2816.
-
(2000)
Neuroreport
, vol.11
, pp. 2811-2816
-
-
Dash, P.K.1
Blum, S.2
Moore, A.N.3
-
12
-
-
0032785021
-
Caspase structure, proteolytic substrates, and function during apoptotic cell death
-
Nicholson, D.W. (1999) Caspase structure, proteolytic substrates, and function during apoptotic cell death. Cell Death Differ., 6, 1028-1042.
-
(1999)
Cell Death Differ
, vol.6
, pp. 1028-1042
-
-
Nicholson, D.W.1
-
13
-
-
73349135640
-
Caspase-6 activation in familial Alzheimer disease brains carrying amyloid precursor protein or presenilin I or presenilin II mutations
-
Albrecht, S., Bogdanovic, N., Ghetti, B., Winblad, B. and LeBlanc, A.C. (2009) Caspase-6 activation in familial Alzheimer disease brains carrying amyloid precursor protein or presenilin I or presenilin II mutations. J. Neuropathol. Exp. Neurol., 68, 1282-1293.
-
(2009)
J. Neuropathol. Exp. Neurol.
, vol.68
, pp. 1282-1293
-
-
Albrecht, S.1
Bogdanovic, N.2
Ghetti, B.3
Winblad, B.4
LeBlanc, A.C.5
-
14
-
-
78149487690
-
Cleavage at the 586 amino acid caspase-6 site in mutant huntingtin influences caspase-6 activation in vivo
-
Graham, R.K., Deng, Y., Carroll, J., Vaid, K., Cowan, C., Pouladi, M.A., Metzler, M., Bissada, N., Wang, L., Faull, R.L.M. et al. (2010) Cleavage at the 586 amino acid caspase-6 site in mutant huntingtin influences caspase-6 activation in vivo. J. Neurosci., 30, 15019-15029.
-
(2010)
J. Neurosci.
, vol.30
, pp. 15019-15029
-
-
Graham, R.K.1
Deng, Y.2
Carroll, J.3
Vaid, K.4
Cowan, C.5
Pouladi, M.A.6
Metzler, M.7
Bissada, N.8
Wang, L.9
Faull, R.L.M.10
-
15
-
-
11144357398
-
Specific caspase interactions and amplification are involved in selective neuronal vulnerability in Huntington's disease
-
Hermel, E., Gafni, J., Propp, S.S., Leavitt, B.R., Wellington, C.L., Young, J.E., Hackam, A.S., Logvinova, A.V., Peel, A.L., Chen, S.F. et al. (2004) Specific caspase interactions and amplification are involved in selective neuronal vulnerability in Huntington's disease. Cell Death Differ., 11, 424-438.
-
(2004)
Cell Death Differ.
, vol.11
, pp. 424-438
-
-
Hermel, E.1
Gafni, J.2
Propp, S.S.3
Leavitt, B.R.4
Wellington, C.L.5
Young, J.E.6
Hackam, A.S.7
Logvinova, A.V.8
Peel, A.L.9
Chen, S.F.10
-
16
-
-
0033601746
-
Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner
-
Slee, E.A., Harte, M.T., Kluck, R.M., Wolf, B.B., Casiano, C.A., Newmeyer, D.D., Wang, H.G., Reed, J.C., Nicholson, D.W., Alnemri, E.S. et al. (1999) Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner. J. Cell Biol., 144, 281-292.
-
(1999)
J. Cell Biol.
, vol.144
, pp. 281-292
-
-
Slee, E.A.1
Harte, M.T.2
Kluck, R.M.3
Wolf, B.B.4
Casiano, C.A.5
Newmeyer, D.D.6
Wang, H.G.7
Reed, J.C.8
Nicholson, D.W.9
Alnemri, E.S.10
-
17
-
-
78650659370
-
Caspase-3 triggers early synaptic dysfunction in a mouse model of Alzheimer's disease
-
D'Amelio, M., Cavallucci, V., Middei, S., Marchetti, C., Pacioni, S., Ferri, A., Diamantini, A., De Zio, D., Carrara, P., Battistini, L. et al. (2011) Caspase-3 triggers early synaptic dysfunction in a mouse model of Alzheimer's disease. Nat. Neurosci., 14, 69-76.
-
(2011)
Nat. Neurosci.
, vol.14
, pp. 69-76
-
-
D'Amelio, M.1
Cavallucci, V.2
Middei, S.3
Marchetti, C.4
Pacioni, S.5
Ferri, A.6
Diamantini, A.7
De Zio, D.8
Carrara, P.9
Battistini, L.10
-
18
-
-
70350324313
-
Reversal of learning deficits in hAPP transgenic mice carrying a mutation at Asp664: a role for early experience. Behav
-
Zhang, J., Gorostiza, O.F., Tang, H., Bredesen, D.E. and Galvan, V. (2010) Reversal of learning deficits in hAPP transgenic mice carrying a mutation at Asp664: a role for early experience. Behav. Brain Res., 206, 202-207.
-
(2010)
Brain Res.
, vol.206
, pp. 202-207
-
-
Zhang, J.1
Gorostiza, O.F.2
Tang, H.3
Bredesen, D.E.4
Galvan, V.5
-
19
-
-
0033617402
-
Involvement of caspases in proteolytic cleavage of Alzheimer's amyloid-beta precursor protein and amyloidogenic A beta peptide formation
-
Gervais, F.G., Xu, D., Robertson, G.S., Vaillancourt, J.P., Zhu, Y., Huang, J., LeBlanc, A., Smith, D., Rigby, M., Shearman, M.S. et al. (1999) Involvement of caspases in proteolytic cleavage of Alzheimer's amyloid-beta precursor protein and amyloidogenic A beta peptide formation. Cell, 97, 395-406.
-
(1999)
Cell
, vol.97
, pp. 395-406
-
-
Gervais, F.G.1
Xu, D.2
Robertson, G.S.3
Vaillancourt, J.P.4
Zhu, Y.5
Huang, J.6
LeBlanc, A.7
Smith, D.8
Rigby, M.9
Shearman, M.S.10
-
20
-
-
34247882772
-
Activation of caspase-6 in aging and mild cognitive impairment
-
Albrecht, S., Bourdeau, M., Bennett, D., Mufson, E.J., Bhattacharjee, M. and LeBlanc, A.C. (2007) Activation of caspase-6 in aging and mild cognitive impairment. Am. J. Pathol., 170, 1200-1209.
-
(2007)
Am. J. Pathol.
, vol.170
, pp. 1200-1209
-
-
Albrecht, S.1
Bourdeau, M.2
Bennett, D.3
Mufson, E.J.4
Bhattacharjee, M.5
LeBlanc, A.C.6
-
21
-
-
0037464386
-
Proteolytic cleavage and cellular toxicity of the human alpha1A calcium channel in spinocerebellar ataxia type 6
-
Kubodera, T., Yokota, T., Ohwada, K., Ishikawa, K., Miura, H., Matsuoka, T. and Mizusawa, H. (2003) Proteolytic cleavage and cellular toxicity of the human alpha1A calcium channel in spinocerebellar ataxia type 6. Neurosci. Lett., 341, 74-78.
-
(2003)
Neurosci. Lett.
, vol.341
, pp. 74-78
-
-
Kubodera, T.1
Yokota, T.2
Ohwada, K.3
Ishikawa, K.4
Miura, H.5
Matsuoka, T.6
Mizusawa, H.7
-
22
-
-
32144436256
-
Proteolytic cleavage of polyglutamine-expanded ataxin-3 is critical for aggregation and sequestration of non-expanded ataxin-3
-
Haacke, A., Broadley, S.A., Boteva, R., Tzvetkov, N., Hartl, F.U. and Breuer, P. (2006) Proteolytic cleavage of polyglutamine-expanded ataxin-3 is critical for aggregation and sequestration of non-expanded ataxin-3. Hum. Mol. Genet., 15, 555-568.
-
(2006)
Hum. Mol. Genet.
, vol.15
, pp. 555-568
-
-
Haacke, A.1
Broadley, S.A.2
Boteva, R.3
Tzvetkov, N.4
Hartl, F.U.5
Breuer, P.6
-
23
-
-
79959314865
-
Intranasal delivery of caspase-9 inhibitor reduces caspase-6-dependent axon/neuron loss and improves neurological function after stroke
-
Akpan, N., Serrano-Saiz, E., Zacharia, B.E., Otten, M.L., Ducruet, A.F., Snipas, S.J., Liu, W., Velloza, J., Cohen, G., Sosunov, S.A. et al. (2011) Intranasal delivery of caspase-9 inhibitor reduces caspase-6-dependent axon/neuron loss and improves neurological function after stroke. J. Neurosci., 31, 8894-8904.
-
(2011)
J. Neurosci.
, vol.31
, pp. 8894-8904
-
-
Akpan, N.1
Serrano-Saiz, E.2
Zacharia, B.E.3
Otten, M.L.4
Ducruet, A.F.5
Snipas, S.J.6
Liu, W.7
Velloza, J.8
Cohen, G.9
Sosunov, S.A.10
-
24
-
-
33646480747
-
Reversal of Alzheimer's-like pathology and behavior in human APP transgenic mice by mutation of Asp664
-
Galvan, V., Gorostiza, O.F., Banwait, S., Ataie, M., Logvinova, A.V., Sitaraman, S., Carlson, E., Sagi, S.A., Chevallier, N., Jin, K. et al. (2006) Reversal of Alzheimer's-like pathology and behavior in human APP transgenic mice by mutation of Asp664. Proc. Natl Acad. Sci. USA, 103, 7130-7135.
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, pp. 7130-7135
-
-
Galvan, V.1
Gorostiza, O.F.2
Banwait, S.3
Ataie, M.4
Logvinova, A.V.5
Sitaraman, S.6
Carlson, E.7
Sagi, S.A.8
Chevallier, N.9
Jin, K.10
-
25
-
-
43849090364
-
Long-term prevention of Alzheimer's disease-like behavioral deficits in PDAPP mice carrying a mutation in Asp664
-
Galvan, V., Zhang, J., Gorostiza, O.F., Banwait, S., Huang, W., Ataie, M., Tang, H. and Bredesen, D.E. (2008) Long-term prevention of Alzheimer's disease-like behavioral deficits in PDAPP mice carrying a mutation in Asp664. Behav. Brain Res., 191, 246-255.
-
(2008)
Behav Brain Res
, vol.191
, pp. 246-255
-
-
Galvan, V.1
Zhang, J.2
Gorostiza, O.F.3
Banwait, S.4
Huang, W.5
Ataie, M.6
Tang, H.7
Bredesen, D.E.8
-
26
-
-
33845898816
-
Deficits in synaptic transmission and learning in amyloid precursor protein (APP) transgenic mice require C-terminal cleavage of APP
-
Saganich, M.J., Schroeder, B.E., Galvan, V., Bredesen, D.E., Koo, E.H. and Heinemann, S.F. (2006) Deficits in synaptic transmission and learning in amyloid precursor protein (APP) transgenic mice require C-terminal cleavage of APP. J. Neurosci., 26, 13428-13436.
-
(2006)
J. Neurosci.
, vol.26
, pp. 13428-13436
-
-
Saganich, M.J.1
Schroeder, B.E.2
Galvan, V.3
Bredesen, D.E.4
Koo, E.H.5
Heinemann, S.F.6
-
27
-
-
38449120482
-
Signal transduction in Alzheimer disease: p21-activated kinase signaling requires C-terminal cleavage of APP at Asp664
-
Nguyen, T.-V.V., Galvan, V., Huang, W., Banwait, S., Tang, H., Zhang, J. and Bredesen, D.E. (2008) Signal transduction in Alzheimer disease: p21-activated kinase signaling requires C-terminal cleavage of APP at Asp664. J. Neurochem., 104, 1065-1080.
-
(2008)
J. Neurochem.
, vol.104
, pp. 1065-1080
-
-
Nguyen, T.-V.1
Galvan, V.2
Huang, W.3
Banwait, S.4
Tang, H.5
Zhang, J.6
Bredesen, D.E.7
-
28
-
-
40549095365
-
C-terminal cleavage of the amyloid-beta protein precursor at Asp664: a switch associated with Alzheimer's disease
-
Banwait, S., Galvan, V., Zhang, J., Gorostiza, O.F., Ataie, M., Huang, W., Crippen, D., Koo, E.H. and Bredesen, D.E. (2008) C-terminal cleavage of the amyloid-beta protein precursor at Asp664: a switch associated with Alzheimer's disease. J. Alzheimers Dis., 13, 1-16.
-
(2008)
J. Alzheimers Dis.
, vol.13
, pp. 1-16
-
-
Banwait, S.1
Galvan, V.2
Zhang, J.3
Gorostiza, O.F.4
Ataie, M.5
Huang, W.6
Crippen, D.7
Koo, E.H.8
Bredesen, D.E.9
-
29
-
-
78650662312
-
Importance of the caspase cleavage site in amyloid-beta protein precursor
-
Bredesen, D.E., John, V. and Galvan, V. (2010) Importance of the caspase cleavage site in amyloid-beta protein precursor. J. Alzheimers Dis., 22, 57-63.
-
(2010)
J. Alzheimers Dis.
, vol.22
, pp. 57-63
-
-
Bredesen, D.E.1
John, V.2
Galvan, V.3
-
30
-
-
74849103981
-
Many neuronal and behavioral impairments in transgenic mouse models of Alzheimer's disease are independent of caspase cleavage of the amyloid precursor protein
-
Harris, J.A., Devidze, N., Halabisky, B., Lo, I., Thwin, M.T., Yu, G.Q., Bredesen, D.E., Masliah, E. and Mucke, L. (2010) Many neuronal and behavioral impairments in transgenic mouse models of Alzheimer's disease are independent of caspase cleavage of the amyloid precursor protein. J. Neurosci., 30, 372-381.
-
(2010)
J. Neurosci.
, vol.30
, pp. 372-381
-
-
Harris, J.A.1
Devidze, N.2
Halabisky, B.3
Lo, I.4
Thwin, M.T.5
Yu, G.Q.6
Bredesen, D.E.7
Masliah, E.8
Mucke, L.9
-
31
-
-
60549089207
-
APP binds DR6 to trigger axon pruning and neuron death via distinct caspases
-
Nikolaev, A., McLaughlin, T., O'Leary, D.D.M. and Tessier-Lavigne, M. (2009) APP binds DR6 to trigger axon pruning and neuron death via distinct caspases. Nature, 457, 981-989.
-
(2009)
Nature
, vol.457
, pp. 981-989
-
-
Nikolaev, A.1
McLaughlin, T.2
O'Leary, D.D.M.3
Tessier-Lavigne, M.4
-
32
-
-
33745003424
-
Cleavage at the caspase-6 site is required for neuronal dysfunction and degeneration due to mutant huntingtin
-
Graham, R.K., Deng, Y., Slow, E.J., Haigh, B., Bissada, N., Lu, G., Pearson, J., Shehadeh, J., Bertram, L., Murphy, Z. et al. (2006) Cleavage at the caspase-6 site is required for neuronal dysfunction and degeneration due to mutant huntingtin. Cell, 125, 1179-1191.
-
(2006)
Cell
, vol.125
, pp. 1179-1191
-
-
Graham, R.K.1
Deng, Y.2
Slow, E.J.3
Haigh, B.4
Bissada, N.5
Lu, G.6
Pearson, J.7
Shehadeh, J.8
Bertram, L.9
Murphy, Z.10
-
33
-
-
79959802847
-
Transgenic mice expressing caspase-6-derived N-terminal fragments of mutant huntingtin develop neurologic abnormalities with predominant cytoplasmic inclusion pathology composed largely of a smaller proteolytic derivative
-
Tebbenkamp, A.T., Green, C., Xu, G., Denovan-Wright, E.M., Rising, A.C., Fromholt, S.E., Brown, H.H., Swing, D., Mandel, R.J., Tessarollo, L. et al. (2011) Transgenic mice expressing caspase-6-derived N-terminal fragments of mutant huntingtin develop neurologic abnormalities with predominant cytoplasmic inclusion pathology composed largely of a smaller proteolytic derivative. Hum. Mol. Genet., 20, 2770-2782.
-
(2011)
Hum. Mol. Genet.
, vol.20
, pp. 2770-2782
-
-
Tebbenkamp, A.T.1
Green, C.2
Xu, G.3
Denovan-Wright, E.M.4
Rising, A.C.5
Fromholt, S.E.6
Brown, H.H.7
Swing, D.8
Mandel, R.J.9
Tessarollo, L.10
-
34
-
-
65249132310
-
Prevention of depressive behaviour in the YAC128 mouse model of Huntington disease by mutation at residue 586 of huntingtin
-
Pouladi, M.A., Graham, R.K., Karasinska, J.M., Xie, Y., Santos, R.D., Petersén, A. and Hayden, M.R. (2009) Prevention of depressive behaviour in the YAC128 mouse model of Huntington disease by mutation at residue 586 of huntingtin. Brain, 132, 919-932.
-
(2009)
Brain
, vol.132
, pp. 919-932
-
-
Pouladi, M.A.1
Graham, R.K.2
Karasinska, J.M.3
Xie, Y.4
Santos, R.D.5
Petersén, A.6
Hayden, M.R.7
-
35
-
-
74549181538
-
Early increase in extrasynaptic NMDA receptor signaling and expression contributes to phenotype onset in Huntington's disease mice
-
Milnerwood, A.J., Gladding, C.M., Pouladi, M.A., Kaufman, A.M., Hines, R.M., Boyd, J.D., Ko, R.W.Y., Vasuta, O.C., Graham, R.K., Hayden, M.R. et al. (2010) Early increase in extrasynaptic NMDA receptor signaling and expression contributes to phenotype onset in Huntington's disease mice. Neuron, 65, 178-190.
-
(2010)
Neuron
, vol.65
, pp. 178-190
-
-
Milnerwood, A.J.1
Gladding, C.M.2
Pouladi, M.A.3
Kaufman, A.M.4
Hines, R.M.5
Boyd, J.D.6
Ko, R.W.Y.7
Vasuta, O.C.8
Graham, R.K.9
Hayden, M.R.10
-
36
-
-
78049342155
-
Phosphorylation of huntingtin at Ser421 in YAC128 neurons is associated with protection of YAC128 neurons from NMDA-mediated excitotoxicity and is modulated by PP1 and PP2A
-
Metzler, M., Gan, L., Mazarei, G., Graham, R.K., Liu, L., Bissada, N., Lu, G., Leavitt, B.R. and Hayden, M.R. (2010) Phosphorylation of huntingtin at Ser421 in YAC128 neurons is associated with protection of YAC128 neurons from NMDA-mediated excitotoxicity and is modulated by PP1 and PP2A. J. Neurosci., 30, 14318-14329.
-
(2010)
J. Neurosci.
, vol.30
, pp. 14318-14329
-
-
Metzler, M.1
Gan, L.2
Mazarei, G.3
Graham, R.K.4
Liu, L.5
Bissada, N.6
Lu, G.7
Leavitt, B.R.8
Hayden, M.R.9
-
37
-
-
78649341457
-
Identification and evaluation of small molecule pan-caspase inhibitors in Huntington's disease models
-
Leyva, M.J., Degiacomo, F., Kaltenbach, L.S., Holcomb, J., Zhang, N., Gafni, J., Park, H., Lo, D.C., Salvesen, G.S., Ellerby, L.M. et al. (2010) Identification and evaluation of small molecule pan-caspase inhibitors in Huntington's disease models. Chem. Biol., 17, 1189-1200.
-
(2010)
Chem. Biol.
, vol.17
, pp. 1189-1200
-
-
Leyva, M.J.1
Degiacomo, F.2
Kaltenbach, L.S.3
Holcomb, J.4
Zhang, N.5
Gafni, J.6
Park, H.7
Lo, D.C.8
Salvesen, G.S.9
Ellerby, L.M.10
-
38
-
-
3042850072
-
Prospects for caspase inhibitors
-
O'Brien, T. and Lee, D. (2004) Prospects for caspase inhibitors. Mini Rev. Med. Chem., 4, 153-165.
-
(2004)
Mini Rev. Med. Chem.
, vol.4
, pp. 153-165
-
-
O'Brien, T.1
Lee, D.2
-
39
-
-
77951667668
-
p75NTR-dependent, myelin-mediated axonal degeneration regulates neural connectivity in the adult brain
-
Park, K.J., Grosso, C.A., Aubert, I., Kaplan, D.R. and Miller, F.D. (2010) p75NTR-dependent, myelin-mediated axonal degeneration regulates neural connectivity in the adult brain. Nat. Neurosci., 13, 559-566.
-
(2010)
Nat. Neurosci.
, vol.13
, pp. 559-566
-
-
Park, K.J.1
Grosso, C.A.2
Aubert, I.3
Kaplan, D.R.4
Miller, F.D.5
-
40
-
-
0029025549
-
Mch2, a new member of the apoptotic Ced-3/Ice cysteine protease gene family
-
Fernandes-Alnemri, T., Litwack, G. and Alnemri, E.S. (1995) Mch2, a new member of the apoptotic Ced-3/Ice cysteine protease gene family. Cancer Res., 55, 2737-2742.
-
(1995)
Cancer Res.
, vol.55
, pp. 2737-2742
-
-
Fernandes-Alnemri, T.1
Litwack, G.2
Alnemri, E.S.3
-
41
-
-
0037012844
-
Axonal self-destruction and neurodegeneration
-
Raff, M.C., Whitmore, A.V. and Finn, J.T. (2002) Axonal self-destruction and neurodegeneration. Science, 296, 868-871.
-
(2002)
Science
, vol.296
, pp. 868-871
-
-
Raff, M.C.1
Whitmore, A.V.2
Finn, J.T.3
-
42
-
-
33747869352
-
Adaptive roles of programmed cell death during nervous system development
-
Buss, R.R., Sun, W. and Oppenheim, R.W. (2006) Adaptive roles of programmed cell death during nervous system development. Annu. Rev. Neurosci., 29, 1-35.
-
(2006)
Annu. Rev. Neurosci.
, vol.29
, pp. 1-35
-
-
Buss, R.R.1
Sun, W.2
Oppenheim, R.W.3
-
43
-
-
44349087637
-
Developmental axon pruning mediated by BDNF-p75NTR-dependent axon degeneration
-
Singh, K.K., Park, K.J., Hong, E.J., Kramer, B.M., Greenberg, M.E., Kaplan, D.R. and Miller, F.D. (2008) Developmental axon pruning mediated by BDNF-p75NTR-dependent axon degeneration. Nat. Neurosci., 11, 649-658.
-
(2008)
Nat. Neurosci.
, vol.11
, pp. 649-658
-
-
Singh, K.K.1
Park, K.J.2
Hong, E.J.3
Kramer, B.M.4
Greenberg, M.E.5
Kaplan, D.R.6
Miller, F.D.7
-
44
-
-
23244436227
-
Axon retraction and degeneration in development and disease
-
Luo, L. and O'Leary, D.D.M. (2005) Axon retraction and degeneration in development and disease. Annu. Rev. Neurosci., 28, 127-156.
-
(2005)
Annu. Rev. Neurosci.
, vol.28
, pp. 127-156
-
-
Luo, L.1
O'Leary, D.D.M.2
-
45
-
-
73749085726
-
Altered white matter microstructure in the corpus callosum in Huntington's disease: implications for cortical disconnection
-
Rosas, H.D., Lee, S.Y., Bender, A.C., Zaleta, A.K., Vangel, M., Yu, P., Fischl, B., Pappu, V., Onorato, C., Cha, J.H., Salat, D.H. and Hersch, S.M. (2010) Altered white matter microstructure in the corpus callosum in Huntington's disease: implications for cortical disconnection. Neuroimage, 49, 2995-3004.
-
(2010)
Neuroimage
, vol.49
, pp. 2995-3004
-
-
Rosas, H.D.1
Lee, S.Y.2
Bender, A.C.3
Zaleta, A.K.4
Vangel, M.5
Yu, P.6
Fischl, B.7
Pappu, V.8
Onorato, C.9
Cha, J.H.10
Salat, D.H.11
Hersch, S.M.12
-
46
-
-
80054766846
-
Early changes in white matter pathways of the sensorimotor cortex in premanifest Huntington's disease
-
Dumas, E.M., van den Bogaard, S.J., Ruber, M.E., Reilman, R.R., Stout, J.C., Craufurd, D., Hicks, S.L., Kennard, C., Tabrizi, S.J., van Buchem, M.A. et al. (2011) Early changes in white matter pathways of the sensorimotor cortex in premanifest Huntington's disease. Hum. Brain Mapp., 33, 203-212.
-
(2011)
Hum. Brain Mapp.
, vol.33
, pp. 203-212
-
-
Dumas, E.M.1
van den Bogaard, S.J.2
Ruber, M.E.3
Reilman, R.R.4
Stout, J.C.5
Craufurd, D.6
Hicks, S.L.7
Kennard, C.8
Tabrizi, S.J.9
van Buchem, M.A.10
-
47
-
-
58149279269
-
Regional white matter volume differences in nondemented aging and Alzheimer's disease
-
Salat, D.H., Greve, D.N., Pacheco, J.L., Quinn, B.T., Helmer, K.G., Buckner, R.L. and Fischl, B. (2009) Regional white matter volume differences in nondemented aging and Alzheimer's disease. Neuroimage, 44, 1247-1258.
-
(2009)
Neuroimage
, vol.44
, pp. 1247-1258
-
-
Salat, D.H.1
Greve, D.N.2
Pacheco, J.L.3
Quinn, B.T.4
Helmer, K.G.5
Buckner, R.L.6
Fischl, B.7
-
48
-
-
0032143986
-
Targeted disruption of the mouse Caspase 8 gene ablates cell death induction by the TNF receptors, Fas/Apo1, and DR3 and is lethal prenatally
-
Varfolomeev, E.E., Schuchmann, M., Luria, V., Chiannilkulchai, N., Beckmann, J.S., Mett, I.L., Rebrikov, D., Brodianski, V.M., Kemper, O.C., Kollet, O. et al. (1998) Targeted disruption of the mouse Caspase 8 gene ablates cell death induction by the TNF receptors, Fas/Apo1, and DR3 and is lethal prenatally. Immunity, 9, 267-276.
-
(1998)
Immunity
, vol.9
, pp. 267-276
-
-
Varfolomeev, E.E.1
Schuchmann, M.2
Luria, V.3
Chiannilkulchai, N.4
Beckmann, J.S.5
Mett, I.L.6
Rebrikov, D.7
Brodianski, V.M.8
Kemper, O.C.9
Kollet, O.10
-
49
-
-
0032493910
-
Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9
-
Kuida, K., Haydar, T.F., Kuan, C.Y., Gu, Y., Taya, C., Karasuyama, H., Su, M.S., Rakic, P. and Flavell, R.A. (1998) Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9. Cell, 94, 325-337.
-
(1998)
Cell
, vol.94
, pp. 325-337
-
-
Kuida, K.1
Haydar, T.F.2
Kuan, C.Y.3
Gu, Y.4
Taya, C.5
Karasuyama, H.6
Su, M.S.7
Rakic, P.8
Flavell, R.A.9
-
50
-
-
0032493870
-
Differential requirement for caspase 9 in apoptotic pathways in vivo
-
Hakem, R., Hakem, A., Duncan, G.S., Henderson, J.T., Woo, M., Soengas, M.S., Elia, A., de la Pompa, J.L., Kagi, D., Khoo, W. et al. (1998) Differential requirement for caspase 9 in apoptotic pathways in vivo. Cell, 94, 339-352.
-
(1998)
Cell
, vol.94
, pp. 339-352
-
-
Hakem, R.1
Hakem, A.2
Duncan, G.S.3
Henderson, J.T.4
Woo, M.5
Soengas, M.S.6
Elia, A.7
de la Pompa, J.L.8
Kagi, D.9
Khoo, W.10
-
51
-
-
7744226465
-
Caspase-7 expanded function and intrinsic expression level underlies strain-specific brain phenotype of caspase-3-null mice
-
Houde, C., Banks, K.G., Coulombe, N., Rasper, D., Grimm, E., Roy, S., Simpson, E.M. and Nicholson, D.W. (2004) Caspase-7 expanded function and intrinsic expression level underlies strain-specific brain phenotype of caspase-3-null mice. J. Neurosci., 24, 9977-9984.
-
(2004)
J. Neurosci.
, vol.24
, pp. 9977-9984
-
-
Houde, C.1
Banks, K.G.2
Coulombe, N.3
Rasper, D.4
Grimm, E.5
Roy, S.6
Simpson, E.M.7
Nicholson, D.W.8
-
52
-
-
77953537855
-
Striatal and white matter predictors of estimated diagnosis for Huntington disease
-
Paulsen, J.S., Nopoulos, P.C., Aylward, E., Ross, C.A., Johnson, H., Magnotta, V.A., Juhl, A., Pierson, R.K., Mills, J., Langbehn, D. et al. (2010) Striatal and white matter predictors of estimated diagnosis for Huntington disease. Brain Res. Bull., 82, 201-207.
-
(2010)
Brain Res. Bull.
, vol.82
, pp. 201-207
-
-
Paulsen, J.S.1
Nopoulos, P.C.2
Aylward, E.3
Ross, C.A.4
Johnson, H.5
Magnotta, V.A.6
Juhl, A.7
Pierson, R.K.8
Mills, J.9
Langbehn, D.10
-
53
-
-
79955950235
-
Natural history of disease in the YAC128 mouse reveals a discrete signature of pathology in Huntington disease
-
Carroll, J.B., Lerch, J.P., Franciosi, S., Spreeuw, A., Bissada, N., Henkelman, R.M. and Hayden, M.R. (2011) Natural history of disease in the YAC128 mouse reveals a discrete signature of pathology in Huntington disease. Neurobiol. Dis., 43, 257-265.
-
(2011)
Neurobiol. Dis.
, vol.43
, pp. 257-265
-
-
Carroll, J.B.1
Lerch, J.P.2
Franciosi, S.3
Spreeuw, A.4
Bissada, N.5
Henkelman, R.M.6
Hayden, M.R.7
-
54
-
-
77953808475
-
Loss of tau elicits axonal degeneration in a mouse model of Alzheimer's disease
-
Dawson, H.N., Cantillana, V., Jansen, M., Wang, H., Vitek, M.P., Wilcock, D.M., Lynch, J.R. and Laskowitz, D.T. (2010) Loss of tau elicits axonal degeneration in a mouse model of Alzheimer's disease. Neuroscience, 169, 516-531.
-
(2010)
Neuroscience
, vol.169
, pp. 516-531
-
-
Dawson, H.N.1
Cantillana, V.2
Jansen, M.3
Wang, H.4
Vitek, M.P.5
Wilcock, D.M.6
Lynch, J.R.7
Laskowitz, D.T.8
-
55
-
-
77958528927
-
Motor deficits, neuron loss, and reduced anxiety coinciding with axonal degeneration and intraneuronal Abeta aggregation in the 5XFAD mouse model of Alzheimer's disease
-
Jawhar, S., Trawicka, A., Jenneckens, C., Bayer, T.A. and Wirths, O. (2010) Motor deficits, neuron loss, and reduced anxiety coinciding with axonal degeneration and intraneuronal Abeta aggregation in the 5XFAD mouse model of Alzheimer's disease. Neurobiol. Aging, 33, e29-e40.
-
(2010)
Neurobiol. Aging
, vol.33
-
-
Jawhar, S.1
Trawicka, A.2
Jenneckens, C.3
Bayer, T.A.4
Wirths, O.5
-
56
-
-
79958855476
-
Familial amyloid precursor protein mutants cause caspase-6-dependent but amyloid b-peptide-independent neuronal degeneration in primary human neuron cultures
-
Sivananthan, S.N., Lee, A.W., Goodyer, C.G. and LeBlanc, A.C. (2010) Familial amyloid precursor protein mutants cause caspase-6-dependent but amyloid b-peptide-independent neuronal degeneration in primary human neuron cultures. Cell Death Dis., 1, e100.
-
(2010)
Cell Death Dis.
, vol.1
-
-
Sivananthan, S.N.1
Lee, A.W.2
Goodyer, C.G.3
LeBlanc, A.C.4
-
57
-
-
0033571743
-
Enhanced sensitivity to N-methyl-D-aspartate receptor activation in transgenic and knockin mouse models of Huntington's disease
-
Levine, M.S., Klapstein, G.J., Koppel, A., Gruen, E., Cepeda, C., Vargas, M.E., Jokel, E.S., Carpenter, E.M., Zanjani, H., Hurst, R.S. et al. (1999) Enhanced sensitivity to N-methyl-D-aspartate receptor activation in transgenic and knockin mouse models of Huntington's disease. J. Neurosci. Res., 58, 515-532.
-
(1999)
J. Neurosci. Res.
, vol.58
, pp. 515-532
-
-
Levine, M.S.1
Klapstein, G.J.2
Koppel, A.3
Gruen, E.4
Cepeda, C.5
Vargas, M.E.6
Jokel, E.S.7
Carpenter, E.M.8
Zanjani, H.9
Hurst, R.S.10
-
58
-
-
0037075624
-
Increased sensitivity to N-methyl-D-aspartate receptor-mediated excitotoxicity in a mouse model of Huntington's disease
-
Zeron, M.M., Hansson, O., Chen, N., Wellington, C.L., Leavitt, B.R., Brundin, P., Hayden, M.R. and Raymond, L.A. (2002) Increased sensitivity to N-methyl-D-aspartate receptor-mediated excitotoxicity in a mouse model of Huntington's disease. Neuron, 33, 849-860.
-
(2002)
Neuron
, vol.33
, pp. 849-860
-
-
Zeron, M.M.1
Hansson, O.2
Chen, N.3
Wellington, C.L.4
Leavitt, B.R.5
Brundin, P.6
Hayden, M.R.7
Raymond, L.A.8
-
59
-
-
30744459353
-
Levels of mutant huntingtin influence the phenotypic severity of Huntington disease in YAC128 mouse models
-
Graham, R.K., Slow, E.J., Deng, Y., Bissada, N., Lu, G., Pearson, J., Shehadeh, J., Leavitt, B.R., Raymond, L.A. and Hayden, M.R. (2006) Levels of mutant huntingtin influence the phenotypic severity of Huntington disease in YAC128 mouse models. Neurobiol. Dis., 21, 444-455.
-
(2006)
Neurobiol. Dis.
, vol.21
, pp. 444-455
-
-
Graham, R.K.1
Slow, E.J.2
Deng, Y.3
Bissada, N.4
Lu, G.5
Pearson, J.6
Shehadeh, J.7
Leavitt, B.R.8
Raymond, L.A.9
Hayden, M.R.10
-
60
-
-
1642295805
-
Potentiation of NMDA receptor-mediated excitotoxicity linked with intrinsic apoptotic pathway in YAC transgenic mouse model of Huntington's disease
-
Zeron, M.M., Fernandes, H.B., Krebs, C., Shehadeh, J., Wellington, C.L., Leavitt, B.R., Baimbridge, K.G., Hayden, M.R. and Raymond, L.A. (2004) Potentiation of NMDA receptor-mediated excitotoxicity linked with intrinsic apoptotic pathway in YAC transgenic mouse model of Huntington's disease. Mol. Cell. Neurosci., 25, 469-479.
-
(2004)
Mol. Cell. Neurosci.
, vol.25
, pp. 469-479
-
-
Zeron, M.M.1
Fernandes, H.B.2
Krebs, C.3
Shehadeh, J.4
Wellington, C.L.5
Leavitt, B.R.6
Baimbridge, K.G.7
Hayden, M.R.8
Raymond, L.A.9
-
61
-
-
10744227174
-
Selective striatal neuronal loss in a YAC128 mouse model of Huntington disease
-
Slow, E.J., van Raamsdonk, J., Rogers, D., Coleman, S.H., Graham, R.K., Deng, Y., Oh, R., Bissada, N., Hossain, S.M., Yang, Y.-Z. et al. (2003) Selective striatal neuronal loss in a YAC128 mouse model of Huntington disease. Hum. Mol. Genet., 12, 1555-1567.
-
(2003)
Hum. Mol. Genet.
, vol.12
, pp. 1555-1567
-
-
Slow, E.J.1
van Raamsdonk, J.2
Rogers, D.3
Coleman, S.H.4
Graham, R.K.5
Deng, Y.6
Oh, R.7
Bissada, N.8
Hossain, S.M.9
Yang, Y.-Z.10
-
62
-
-
17644368893
-
Cognitive dysfunction precedes neuropathology and motor abnormalities in the YAC128 mouse model of Huntington's disease
-
Van Raamsdonk, J.M., Pearson, J., Slow, E.J., Hossain, S.M., Leavitt, B.R. and Hayden, M.R. (2005) Cognitive dysfunction precedes neuropathology and motor abnormalities in the YAC128 mouse model of Huntington's disease. J. Neurosci., 25, 4169-4180.
-
(2005)
J. Neurosci.
, vol.25
, pp. 4169-4180
-
-
Van Raamsdonk, J.M.1
Pearson, J.2
Slow, E.J.3
Hossain, S.M.4
Leavitt, B.R.5
Hayden, M.R.6
-
63
-
-
13044287361
-
Plaque-independent disruption of neural circuits in Alzheimer's disease mouse models
-
Hsia, A.Y., Masliah, E., McConlogue, L., Yu, G.Q., Tatsuno, G., Hu, K., Kholodenko, D., Malenka, R.C., Nicoll, R.A. and Mucke, L. (1999) Plaque-independent disruption of neural circuits in Alzheimer's disease mouse models. Proc. Natl Acad. Sci. USA, 96, 3228-3233.
-
(1999)
Proc. Natl Acad. Sci. USA
, vol.96
, pp. 3228-3233
-
-
Hsia, A.Y.1
Masliah, E.2
McConlogue, L.3
Yu, G.Q.4
Tatsuno, G.5
Hu, K.6
Kholodenko, D.7
Malenka, R.C.8
Nicoll, R.A.9
Mucke, L.10
-
64
-
-
78751626397
-
Regulation of caspases in the nervous system implications for functions in health and disease
-
Troy, C.M., Akpan, N. and Jean, Y.Y. (2011) Regulation of caspases in the nervous system implications for functions in health and disease. Prog. Mol. Biol. Transl. Sci., 99, 265-305.
-
(2011)
Prog. Mol. Biol. Transl. Sci.
, vol.99
, pp. 265-305
-
-
Troy, C.M.1
Akpan, N.2
Jean, Y.Y.3
-
65
-
-
0033551738
-
Caspase-6 role in apoptosis of human neurons, amyloidogenesis, and Alzheimer's disease
-
LeBlanc, A., Liu, H., Goodyer, C., Bergeron, C. and Hammond, J. (1999) Caspase-6 role in apoptosis of human neurons, amyloidogenesis, and Alzheimer's disease. J. Biol. Chem., 274, 23426-23436.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 23426-23436
-
-
LeBlanc, A.1
Liu, H.2
Goodyer, C.3
Bergeron, C.4
Hammond, J.5
-
66
-
-
0036077250
-
Expression and differential processing of caspases 6 and 7 in relation to specific epileptiform EEG patterns following limbic seizures
-
Henshall, D.C., Skradski, S.L., Meller, R., Araki, T., Minami, M., Schindler, C.K., Lan, J.Q., Bonislawski, D.P. and Simon, R.P. (2002) Expression and differential processing of caspases 6 and 7 in relation to specific epileptiform EEG patterns following limbic seizures. Neurobiol. Dis., 10, 71-87.
-
(2002)
Neurobiol. Dis.
, vol.10
, pp. 71-87
-
-
Henshall, D.C.1
Skradski, S.L.2
Meller, R.3
Araki, T.4
Minami, M.5
Schindler, C.K.6
Lan, J.Q.7
Bonislawski, D.P.8
Simon, R.P.9
-
67
-
-
14644399264
-
Caspase 6 expression in the rat hippocampus during epileptogenesis and epilepsy
-
Narkilahti, S. and Pitkänen, A. (2005) Caspase 6 expression in the rat hippocampus during epileptogenesis and epilepsy. Neuroscience, 131, 887-897.
-
(2005)
Neuroscience
, vol.131
, pp. 887-897
-
-
Narkilahti, S.1
Pitkänen, A.2
-
68
-
-
67349094570
-
Neuroprotection by NGF and BDNF against neurotoxin-exerted apoptotic death in neural stem cells are mediated through Trk receptors, activating PI3-kinase and MAPK pathways
-
Nguyen, N., Lee, S.B., Lee, Y.S., Lee, Y.S., Lee, K.-H. and Ahn, J.-Y. (2009) Neuroprotection by NGF and BDNF against neurotoxin-exerted apoptotic death in neural stem cells are mediated through Trk receptors, activating PI3-kinase and MAPK pathways. Neurochem. Res., 34, 942-951.
-
(2009)
Neurochem. Res.
, vol.34
, pp. 942-951
-
-
Nguyen, N.1
Lee, S.B.2
Lee, Y.S.3
Lee, Y.S.4
Lee, K.-H.5
Ahn, J.-Y.6
-
69
-
-
50549103561
-
Death receptors and caspases but not mitochondria are activated in the GDNF- or BDNF-deprived dopaminergic neurons
-
Yu, L.-Y., Saarma, M. and Arumäe, U. (2008) Death receptors and caspases but not mitochondria are activated in the GDNF- or BDNF-deprived dopaminergic neurons. J. Neurosci., 28, 7467-7475.
-
(2008)
J. Neurosci.
, vol.28
, pp. 7467-7475
-
-
Yu, L.-Y.1
Saarma, M.2
Arumäe, U.3
-
70
-
-
77957346562
-
Neuroprotection signaling pathway of nerve growth factor and brain-derived neurotrophic factor against staurosporine induced apoptosis in hippocampal H19-7/IGF-IR [corrected]
-
Nguyen, T.L., Kim, C.K., Cho, J.H., Lee, K.H. and Ahn, J.Y. (2010) Neuroprotection signaling pathway of nerve growth factor and brain-derived neurotrophic factor against staurosporine induced apoptosis in hippocampal H19-7/IGF-IR [corrected]. Exp. Mol. Med., 42, 583-595.
-
(2010)
Exp. Mol. Med.
, vol.42
, pp. 583-595
-
-
Nguyen, T.L.1
Kim, C.K.2
Cho, J.H.3
Lee, K.H.4
Ahn, J.Y.5
-
71
-
-
45549106668
-
Impaired GABAergic inhibition in the visual cortex of brain-derived neurotrophic factor heterozygous knockout mice
-
Abidin, I., Eysel, U.T., Lessmann, V. and Mittmann, T. (2008) Impaired GABAergic inhibition in the visual cortex of brain-derived neurotrophic factor heterozygous knockout mice. J. Physiol. (Lond.), 586, 1885-1901.
-
(2008)
J. Physiol. (Lond.)
, vol.586
, pp. 1885-1901
-
-
Abidin, I.1
Eysel, U.T.2
Lessmann, V.3
Mittmann, T.4
-
72
-
-
41149120733
-
Protein synthesis and neurotrophin-dependent structural plasticity of single dendritic spines
-
Tanaka, J.-I., Horiike, Y., Matsuzaki, M., Miyazaki, T., Ellis-Davies, G.C.R. and Kasai, H. (2008) Protein synthesis and neurotrophin-dependent structural plasticity of single dendritic spines. Science, 319, 1683-1687.
-
(2008)
Science
, vol.319
, pp. 1683-1687
-
-
Tanaka, J.-I.1
Horiike, Y.2
Matsuzaki, M.3
Miyazaki, T.4
Ellis-Davies, G.C.R.5
Kasai, H.6
-
73
-
-
0035234670
-
Neurotrophins as synaptic modulators
-
Poo, M.M. (2001) Neurotrophins as synaptic modulators. Nat. Rev. Neurosci., 2, 24-32.
-
(2001)
Nat. Rev. Neurosci.
, vol.2
, pp. 24-32
-
-
Poo, M.M.1
-
74
-
-
78649848073
-
Characterisation of a new regulator of BDNF signalling, Sprouty3, involved in axonal morphogenesis in vivo
-
Panagiotaki, N., Dajas-Bailador, F., Amaya, E., Papalopulu, N. and Dorey, K. (2010) Characterisation of a new regulator of BDNF signalling, Sprouty3, involved in axonal morphogenesis in vivo. Development, 137, 4005-4015.
-
(2010)
Development
, vol.137
, pp. 4005-4015
-
-
Panagiotaki, N.1
Dajas-Bailador, F.2
Amaya, E.3
Papalopulu, N.4
Dorey, K.5
-
75
-
-
34548721613
-
Sprouty2 inhibits BDNF-induced signaling and modulates neuronal differentiation and survival
-
Gross, I., Armant, O., Benosman, S., de Aguilar, J.L., Freund, J.N., Kedinger, M., Licht, J.D., Gaiddon, C. and Loeffler, J.P. (2007) Sprouty2 inhibits BDNF-induced signaling and modulates neuronal differentiation and survival. Cell Death Differ., 14, 1802-1812.
-
(2007)
Cell Death Differ.
, vol.14
, pp. 1802-1812
-
-
Gross, I.1
Armant, O.2
Benosman, S.3
de Aguilar, J.L.4
Freund, J.N.5
Kedinger, M.6
Licht, J.D.7
Gaiddon, C.8
Loeffler, J.P.9
-
76
-
-
0042133327
-
Brain-derived neurotrophic factor is required for the maintenance of cortical dendrites
-
Gorski, J.A., Zeiler, S.R., Tamowski, S. and Jones, K.R. (2003) Brain-derived neurotrophic factor is required for the maintenance of cortical dendrites. J. Neurosci., 23, 6856-6865.
-
(2003)
J. Neurosci.
, vol.23
, pp. 6856-6865
-
-
Gorski, J.A.1
Zeiler, S.R.2
Tamowski, S.3
Jones, K.R.4
-
77
-
-
40449100043
-
BDNF and memory formation and storage
-
Bekinschtein, P., Cammarota, M., Izquierdo, I. and Medina, J.H. (2008) BDNF and memory formation and storage. Neuroscientist, 14, 147-156.
-
(2008)
Neuroscientist
, vol.14
, pp. 147-156
-
-
Bekinschtein, P.1
Cammarota, M.2
Izquierdo, I.3
Medina, J.H.4
-
78
-
-
40649120726
-
BDNF is essential to promote persistence of long-term memory storage
-
Bekinschtein, P., Cammarota, M., Katche, C., Slipczuk, L., Rossato, J.I., Goldin, A., Izquierdo, I. and Medina, J.H. (2008) BDNF is essential to promote persistence of long-term memory storage. Proc. Natl Acad. Sci. USA, 105, 2711-2716.
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 2711-2716
-
-
Bekinschtein, P.1
Cammarota, M.2
Katche, C.3
Slipczuk, L.4
Rossato, J.I.5
Goldin, A.6
Izquierdo, I.7
Medina, J.H.8
-
79
-
-
76149121821
-
Global deprivation of brain-derived neurotrophic factor in the CNS reveals an area-specific requirement for dendritic growth
-
Rauskolb, S., Zagrebelsky, M., Dreznjak, A., Deogracias, R., Matsumoto, T., Wiese, S., Erne, B., Sendtner, M., Schaeren-Wiemers, N., Korte, M. et al. (2010) Global deprivation of brain-derived neurotrophic factor in the CNS reveals an area-specific requirement for dendritic growth. J. Neurosci., 30, 1739-1749.
-
(2010)
J. Neurosci.
, vol.30
, pp. 1739-1749
-
-
Rauskolb, S.1
Zagrebelsky, M.2
Dreznjak, A.3
Deogracias, R.4
Matsumoto, T.5
Wiese, S.6
Erne, B.7
Sendtner, M.8
Schaeren-Wiemers, N.9
Korte, M.10
-
80
-
-
79957557376
-
Phenylbutyrate rescues dendritic spine loss associated with memory deficits in a mouse model of Alzheimer disease
-
[Epub ahead of print]
-
Ricobaraza, A., Cuadrado-Tejedor, M., Marco, S., Perez-Otano, I. and Garcia-Osta, A. (2010) Phenylbutyrate rescues dendritic spine loss associated with memory deficits in a mouse model of Alzheimer disease. Hippocampus. [Epub ahead of print].
-
(2010)
Hippocampus
-
-
Ricobaraza, A.1
Cuadrado-Tejedor, M.2
Marco, S.3
Perez-Otano, I.4
Garcia-Osta, A.5
-
81
-
-
0037092425
-
Brain-derived neurotrophic factor produces antidepressant effects in behavioral models of depression
-
Shirayama, Y., Chen, A.C.-H., Nakagawa, S., Russell, D.S. and Duman, R.S. (2002) Brain-derived neurotrophic factor produces antidepressant effects in behavioral models of depression. J. Neurosci., 22, 3251-3261.
-
(2002)
J. Neurosci.
, vol.22
, pp. 3251-3261
-
-
Shirayama, Y.1
Chen, A.-H.2
Nakagawa, S.3
Russell, D.S.4
Duman, R.S.5
-
82
-
-
0242559031
-
Brain-derived neurotrophic factor in the ventral midbrain-nucleus accumbens pathway: a role in depression
-
Eisch, A.J., Bolaños, C.A., de Wit, J., Simonak, R.D., Pudiak, C.M., Barrot, M., Verhaagen, J. and Nestler, E.J. (2003) Brain-derived neurotrophic factor in the ventral midbrain-nucleus accumbens pathway: a role in depression. Biol. Psychiatry, 54, 994-1005.
-
(2003)
Biol. Psychiatry
, vol.54
, pp. 994-1005
-
-
Eisch, A.J.1
Bolaños, C.A.2
de Wit, J.3
Simonak, R.D.4
Pudiak, C.M.5
Barrot, M.6
Verhaagen, J.7
Nestler, E.J.8
-
83
-
-
32444451651
-
Essential role of BDNF in the mesolimbic dopamine pathway in social defeat stress
-
Berton, O., McClung, C.A., Dileone, R.J., Krishnan, V., Renthal, W., Russo, S.J., Graham, D., Tsankova, N.M., Bolanos, C.A., Rios, M. et al. (2006) Essential role of BDNF in the mesolimbic dopamine pathway in social defeat stress. Science, 311, 864-868.
-
(2006)
Science
, vol.311
, pp. 864-868
-
-
Berton, O.1
McClung, C.A.2
Dileone, R.J.3
Krishnan, V.4
Renthal, W.5
Russo, S.J.6
Graham, D.7
Tsankova, N.M.8
Bolanos, C.A.9
Rios, M.10
-
84
-
-
77954330883
-
Alpha-synuclein-and MPTP-generated rodent models of Parkinsons disease and the study of extracellular striatal dopamine dynamics: a microdialysis approach
-
Bazzu, G., Calia, G., Puggioni, G., Spissu, Y., Rocchitta, G., Debetto, P., Grigoletto, J., Zusso, M., Migheli, R., Serra, P.A., Desole, M.S. and Miele, E. (2010) Alpha-synuclein-and MPTP-generated rodent models of Parkinsons disease and the study of extracellular striatal dopamine dynamics: a microdialysis approach. CNS Neurol. Disord. Drug Targets, 9, 482-490.
-
(2010)
CNS Neurol. Disord. Drug Targets
, vol.9
, pp. 482-490
-
-
Bazzu, G.1
Calia, G.2
Puggioni, G.3
Spissu, Y.4
Rocchitta, G.5
Debetto, P.6
Grigoletto, J.7
Zusso, M.8
Migheli, R.9
Serra, P.A.10
Desole, M.S.11
Miele, E.12
-
85
-
-
0030927941
-
Extensive cytotoxic lesions involving both the rhinal cortices and area TE impair recognition but spare spatial alternation in the rat
-
Aggleton, J.P., Keen, S., Warburton, E.C. and Bussey, T.J. (1997) Extensive cytotoxic lesions involving both the rhinal cortices and area TE impair recognition but spare spatial alternation in the rat. Brain Res. Bull., 43, 279-287.
-
(1997)
Brain Res. Bull.
, vol.43
, pp. 279-287
-
-
Aggleton, J.P.1
Keen, S.2
Warburton, E.C.3
Bussey, T.J.4
-
86
-
-
0035124076
-
The effect of excitotoxic lesions centered on the hippocampus or perirhinal cortex in object recognition and spatial memory tasks
-
Liu, P. and Bilkey, D.K. (2001) The effect of excitotoxic lesions centered on the hippocampus or perirhinal cortex in object recognition and spatial memory tasks. Behav. Neurosci., 115, 94-111.
-
(2001)
Behav. Neurosci.
, vol.115
, pp. 94-111
-
-
Liu, P.1
Bilkey, D.K.2
-
87
-
-
0035228401
-
Recognition memory: what are the roles of the perirhinal cortex and hippocampus?
-
Brown, M.W. and Aggleton, J.P. (2001) Recognition memory: what are the roles of the perirhinal cortex and hippocampus? Nat. Rev. Neurosci., 2, 51-61.
-
(2001)
Nat. Rev. Neurosci.
, vol.2
, pp. 51-61
-
-
Brown, M.W.1
Aggleton, J.P.2
-
88
-
-
0032848327
-
Differential neuronal responsiveness in primate perirhinal cortex and hippocampal formation during performance of a conditional visual discrimination task
-
Xiang, J.Z. and Brown, M.W. (1999) Differential neuronal responsiveness in primate perirhinal cortex and hippocampal formation during performance of a conditional visual discrimination task. Eur. J. Neurosci., 11, 3715-3724.
-
(1999)
Eur. J. Neurosci.
, vol.11
, pp. 3715-3724
-
-
Xiang, J.Z.1
Brown, M.W.2
-
89
-
-
30844468003
-
Caspase-1 activation of caspase-6 in human apoptotic neurons
-
Guo, H., Pétrin, D., Zhang, Y., Bergeron, C., Goodyer, C.G. and LeBlanc, A.C. (2006) Caspase-1 activation of caspase-6 in human apoptotic neurons. Cell Death Differ., 13, 285-292.
-
(2006)
Cell Death Differ.
, vol.13
, pp. 285-292
-
-
Guo, H.1
Pétrin, D.2
Zhang, Y.3
Bergeron, C.4
Goodyer, C.G.5
LeBlanc, A.C.6
-
90
-
-
33747884332
-
Learning-memory deficit with aging in APP transgenic mice of Alzheimer's disease and intervention by using tetrahydroxystilbene glucoside
-
Zhang, L., Xing, Y., Ye, C.F., Ai, H.X., Wei, H.F. and Li, L. (2006) Learning-memory deficit with aging in APP transgenic mice of Alzheimer's disease and intervention by using tetrahydroxystilbene glucoside. Behav. Brain Res., 173, 246-254.
-
(2006)
Behav. Brain Res.
, vol.173
, pp. 246-254
-
-
Zhang, L.1
Xing, Y.2
Ye, C.F.3
Ai, H.X.4
Wei, H.F.5
Li, L.6
-
91
-
-
51649095677
-
Kihi-to, a herbal traditional medicine, improves Abeta(25-35)-induced memory impairment and losses of neurites and synapses
-
Tohda, C., Naito, R. and Joyashiki, E. (2008) Kihi-to, a herbal traditional medicine, improves Abeta(25-35)-induced memory impairment and losses of neurites and synapses. BMC Complement. Altern. Med., 8, 49.
-
(2008)
BMC Complement. Altern. Med.
, vol.8
, pp. 49
-
-
Tohda, C.1
Naito, R.2
Joyashiki, E.3
-
92
-
-
69949090346
-
Spermine improves recognition memory deficit in a rodent model of Huntington's disease
-
Velloso, N.A., Dalmolin, G.D., Gomes, G.M., Rubin, M.A., Canas, P.M., Cunha, R.A. and Mello, C.F. (2009) Spermine improves recognition memory deficit in a rodent model of Huntington's disease. Neurobiol. Learn. Mem., 92, 574-580.
-
(2009)
Neurobiol. Learn. Mem.
, vol.92
, pp. 574-580
-
-
Velloso, N.A.1
Dalmolin, G.D.2
Gomes, G.M.3
Rubin, M.A.4
Canas, P.M.5
Cunha, R.A.6
Mello, C.F.7
-
93
-
-
0035852759
-
The effects of aging on gene expression in the hypothalamus and cortex of mice
-
Jiang, C.H., Tsien, J.Z., Schultz, P.G. and Hu, Y. (2001) The effects of aging on gene expression in the hypothalamus and cortex of mice. Proc. Natl Acad. Sci. USA, 98, 1930-1934.
-
(2001)
Proc. Natl Acad. Sci. USA
, vol.98
, pp. 1930-1934
-
-
Jiang, C.H.1
Tsien, J.Z.2
Schultz, P.G.3
Hu, Y.4
-
94
-
-
0037107151
-
Caspase cleavage of mutant huntingtin precedes neurodegeneration in Huntington's disease
-
Wellington, C.L., Ellerby, L.M., Gutekunst, C.-A., Rogers, D., Warby, S., Graham, R.K., Loubser, O., van Raamsdonk, J., Singaraja, R., Yang, Y.-Z. et al. (2002) Caspase cleavage of mutant huntingtin precedes neurodegeneration in Huntington's disease. J. Neurosci., 22, 7862-7872.
-
(2002)
J. Neurosci.
, vol.22
, pp. 7862-7872
-
-
Wellington, C.L.1
Ellerby, L.M.2
Gutekunst, C.-A.3
Rogers, D.4
Warby, S.5
Graham, R.K.6
Loubser, O.7
van Raamsdonk, J.8
Singaraja, R.9
Yang, Y.-Z.10
-
95
-
-
0344304552
-
Critical function of endogenous XIAP in regulating caspase activation during sympathetic neuronal apoptosis
-
Potts, P.R., Singh, S., Knezek, M., Thompson, C.B. and Deshmukh, M. (2003) Critical function of endogenous XIAP in regulating caspase activation during sympathetic neuronal apoptosis. J. Cell Biol., 163, 789-799.
-
(2003)
J. Cell Biol.
, vol.163
, pp. 789-799
-
-
Potts, P.R.1
Singh, S.2
Knezek, M.3
Thompson, C.B.4
Deshmukh, M.5
-
96
-
-
10044250013
-
Modulation of muscle spindle innervation by neurotrophin-3 following nerve injury
-
Taylor, M.D., Holdeman, A.S., Weltmer, S.G., Ryals, J.M. and Wright, D.E. (2005) Modulation of muscle spindle innervation by neurotrophin-3 following nerve injury. Exp. Neurol., 191, 211-222.
-
(2005)
Exp. Neurol.
, vol.191
, pp. 211-222
-
-
Taylor, M.D.1
Holdeman, A.S.2
Weltmer, S.G.3
Ryals, J.M.4
Wright, D.E.5
-
97
-
-
0025995529
-
Magnetic resonance imaging (MRI) and model-free estimates of brain volume determined using the Cavalieri principle
-
Mayhew, T.M. and Olsen, D.R. (1991) Magnetic resonance imaging (MRI) and model-free estimates of brain volume determined using the Cavalieri principle. J. Anat., 178, 133-144.
-
(1991)
J. Anat.
, vol.178
, pp. 133-144
-
-
Mayhew, T.M.1
Olsen, D.R.2
-
98
-
-
78049481215
-
A stereological study of MRI and the Cavalieri principle combined for diagnosis and monitoring of brain tumor volume
-
Sonmez, O.F., Odaci, E., Bas, O., Colakoglu, S., Sahin, B., Bilgic, S. and Kaplan, S. (2010) A stereological study of MRI and the Cavalieri principle combined for diagnosis and monitoring of brain tumor volume. J. Clin. Neurosci., 17, 1499-1502.
-
(2010)
J. Clin. Neurosci.
, vol.17
, pp. 1499-1502
-
-
Sonmez, O.F.1
Odaci, E.2
Bas, O.3
Colakoglu, S.4
Sahin, B.5
Bilgic, S.6
Kaplan, S.7
|