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Volumn 68, Issue 12, 2009, Pages 1282-1293

Caspase-6 activation in familial alzheimer disease brains carrying amyloid precursor protein or presenilin i or presenilin II mutations

Author keywords

Alzheimer disease; Arctic mutation; Casp 6; Familial Alzheimer disease; Presenilin I mutation; Sporadic Alzheimer disease; Swedish mutation; Tau cleaved by Casp 6

Indexed keywords

AMYLOID PROTEIN; CASPASE 6; PRESENILIN 1; PRESENILIN 2; TAU PROTEIN; AMYLOID PRECURSOR PROTEIN;

EID: 73349135640     PISSN: 00223069     EISSN: None     Source Type: Journal    
DOI: 10.1097/NEN.0b013e3181c1da10     Document Type: Article
Times cited : (67)

References (25)
  • 1
    • 0037833742 scopus 로고    scopus 로고
    • Caspase-activation pathways in apoptosis and immunity
    • Creagh EM, Conroy H, Martin SJ. Caspase-activation pathways in apoptosis and immunity. Immunol Rev 2003;193:10-21
    • (2003) Immunol Rev , vol.193 , pp. 10-21
    • Creagh, E.M.1    Conroy, H.2    Martin, S.J.3
  • 2
    • 0033617402 scopus 로고    scopus 로고
    • Involvement of caspases in pro-teolytic cleavage of Alzheimer's A-amyloid precursor protein and amyloidogenic A-peptide formation
    • Gervais F, Xu D, Robertson G, et al. Involvement of caspases in pro-teolytic cleavage of Alzheimer's A-amyloid precursor protein and amyloidogenic A-peptide formation. Cell 1999;97:395-406
    • (1999) Cell , vol.97 , pp. 395-406
    • Gervais, F.1    Xu, D.2    Robertson, G.3
  • 3
    • 0033551738 scopus 로고    scopus 로고
    • Caspase-6 role in apoptosis of human neurons, amyloidogenesis and Alzheimer's disease
    • LeBlanc AC, Liu H, Goodyer C, et al. Caspase-6 role in apoptosis of human neurons, amyloidogenesis and Alzheimer's disease. J Biol Chem 1999;274:23426-23436
    • (1999) J Biol Chem , vol.274 , pp. 23426-23436
    • Leblanc, A.C.1    Liu, H.2    Goodyer, C.3
  • 4
    • 0242412504 scopus 로고    scopus 로고
    • Caspase activation increases beta-amyloid generation independently of caspase cleavage of the beta-amyloid precursor protein (APP)
    • Tesco G, Koh YH, Tanzi RE. Caspase activation increases beta-amyloid generation independently of caspase cleavage of the beta-amyloid precursor protein (APP). J Biol Chem 2003;278:4607-4680
    • (2003) J Biol Chem , vol.278 , pp. 4607-4680
    • Tesco, G.1    Koh, Y.H.2    Tanzi, R.E.3
  • 5
    • 3242811902 scopus 로고    scopus 로고
    • Active caspase-6 and caspase-6 cleaved tau in neuropil threads, neuritic plaques and neurofibrillary tangles of Alzheimer's disease
    • Guo H, Albrecht S, Bourdeau M, et al. Active caspase-6 and caspase-6 cleaved tau in neuropil threads, neuritic plaques and neurofibrillary tangles of Alzheimer's disease. Am J Pathol 2004;165:523-531
    • (2004) Am J Pathol , vol.165 , pp. 523-531
    • Guo, H.1    Albrecht, S.2    Bourdeau, M.3
  • 7
    • 0034668842 scopus 로고    scopus 로고
    • Selective and protracted apoptosis in human primary neurons microinjected with active caspase 3,6,7, and 8
    • Zhang Y, Goodyer C, LeBlanc A. Selective and protracted apoptosis in human primary neurons microinjected with active caspase-3,-6,-7, and-8. J Neurosci 2000;20:8384-8389
    • (2000) J Neurosci , vol.20 , pp. 8384-8389
    • Zhang, Y.1    Goodyer, C.2    Leblanc, A.3
  • 8
    • 60649093275 scopus 로고    scopus 로고
    • Self-activation of caspase-6 in vitro and in vivo: Caspase-6 activation does not induce cell death in HEK293T cells
    • Klaiman G, Champagne N, LeBlanc AC. Self-activation of caspase-6 in vitro and in vivo: Caspase-6 activation does not induce cell death in HEK293T cells. Biochim Biophys Acta 2009;1793:592-601
    • (2009) Biochim Biophys Acta , vol.1793 , pp. 592-601
    • Klaiman, G.1    Champagne, N.2    Leblanc, A.C.3
  • 9
    • 0037090614 scopus 로고    scopus 로고
    • Caspase-6 gene disruption reveals a requirement for lamin A cleavage in apoptotic chromatin condensation
    • Ruchaud S, Korfali N, Villa P, et al. Caspase-6 gene disruption reveals a requirement for lamin A cleavage in apoptotic chromatin condensation. EMBO J 2002;21:1967-1977
    • (2002) EMBO J , vol.21 , pp. 1967-1977
    • Ruchaud, S.1    Korfali, N.2    Villa, P.3
  • 10
    • 50249086898 scopus 로고    scopus 로고
    • Targets of caspase-6 activity in human neurons and Alzheimer disease
    • Klaiman G, Petzke TL, Hammond J, et al. Targets of caspase-6 activity in human neurons and Alzheimer disease. Mol Cell Proteomics 2008;7: 1541-1555
    • (2008) Mol Cell Proteomics , vol.7 , pp. 1541-1555
    • Klaiman, G.1    Petzke, T.L.2    Hammond, J.3
  • 11
    • 60549089207 scopus 로고    scopus 로고
    • APP binds DR6 to trigger axon pruning and neuron death via distinct caspases
    • Nikolaev A, McLaughlin T, O'Leary DD, et al. APP binds DR6 to trigger axon pruning and neuron death via distinct caspases. Nature 2009; 457:981-989
    • (2009) Nature , vol.457 , pp. 981-989
    • Nikolaev, A.1    McLaughlin, T.2    O'Leary, D.D.3
  • 12
    • 0029609021 scopus 로고
    • Increased production of 4 kDa amyloid beta peptide in serum deprived human primary neuron cultures: Possible involvement of apoptosis
    • LeBlanc A. Increased production of 4 kDa amyloid beta peptide in serum deprived human primary neuron cultures: Possible involvement of apoptosis. J Neurosci 1995;15:7837-7846
    • (1995) J Neurosci , vol.15 , pp. 7837-7846
    • Leblanc, A.1
  • 13
    • 0025908356 scopus 로고
    • The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). 2. Standardization of the neu-ropathologic assessment of Alzheimer's disease
    • Mirra SS, Heyman A, McKeel D, et al. The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). 2. Standardization of the neu-ropathologic assessment of Alzheimer's disease. Neurol 1991;41:479-486
    • (1991) Neurol , Issue.41 , pp. 479-486
    • Mirra, S.S.1    Heyman, A.2    McKeel, D.3    Al, E.4
  • 14
    • 0033762710 scopus 로고    scopus 로고
    • Variant Alzheimer's disease with spastic paraparesis and cotton wool plaques is caused by PS-1 mutations that lead to exceptionally high amyloid-beta concentrations
    • Houlden H, Baker M, McGowan E, et al. Variant Alzheimer's disease with spastic paraparesis and cotton wool plaques is caused by PS-1 mutations that lead to exceptionally high amyloid-beta concentrations. Ann Neurol 2000;48:806-808
    • (2000) Ann Neurol , vol.48 , pp. 806-808
    • Houlden, H.1    Baker, M.2    McGowan, E.3
  • 15
    • 23844551164 scopus 로고    scopus 로고
    • Amino-terminally truncated Abeta peptide species are the main component of cotton wool plaques
    • Miravalle L, Calero M, Takao M, et al. Amino-terminally truncated Abeta peptide species are the main component of cotton wool plaques. Biochemistry 2005;44:10810-10821
    • (2005) Biochemistry , vol.44 , pp. 10810-10821
    • Miravalle, L.1    Calero, M.2    Takao, M.3
  • 16
    • 0037010284 scopus 로고    scopus 로고
    • Alzheimer's disease with spastic paresis and cotton wool type plaques
    • Tabira T, Chui DH, Nakayama H, et al. Alzheimer's disease with spastic paresis and cotton wool type plaques. J Neurosci Res 2002;70:367-372
    • (2002) J Neurosci Res , vol.70 , pp. 367-372
    • Tabira, T.1    Chui, D.H.2    Nakayama, H.3
  • 17
    • 42249102801 scopus 로고    scopus 로고
    • Clinical and neuropa-thological features of the arctic APP gene mutation causing early-onset Alzheimer disease
    • Basun H, Bogdanovic N, Ingelsson M, et al. Clinical and neuropa-thological features of the arctic APP gene mutation causing early-onset Alzheimer disease. Arch Neurol 2008;65:499-505
    • (2008) Arch Neurol , vol.65 , pp. 499-505
    • Basun, H.1    Bogdanovic, N.2    Ingelsson, M.3
  • 18
    • 3142514201 scopus 로고    scopus 로고
    • Protein aggregation and neurodegenerative disease
    • Ross CA, Poirier MA. Protein aggregation and neurodegenerative disease. Nat Med 2004;(suppl 10):S10-17
    • (2004) Nat Med , Issue.SUPPL. 10
    • Ross, C.A.1    Poirier, M.A.2
  • 19
    • 0034689052 scopus 로고    scopus 로고
    • Active caspases and cleaved cytokeratins are sequestered into cytoplasmic inclusions in TRAIL-induced apoptosis
    • MacFarlane M, Merrison W, Dinsdale D, et al. Active caspases and cleaved cytokeratins are sequestered into cytoplasmic inclusions in TRAIL-induced apoptosis. J Cell Biol 2000;148:1239-1254
    • (2000) J Cell Biol , vol.148 , pp. 1239-1254
    • MacFarlane, M.1    Merrison, W.2    Dinsdale, D.3
  • 20
    • 1542289716 scopus 로고    scopus 로고
    • Intermediate filaments control the intracellular distribution of caspases during apoptosis
    • Dinsdale D, Lee JC, Dewson G, et al. Intermediate filaments control the intracellular distribution of caspases during apoptosis. Am J Pathol 2004; 164:395-407
    • (2004) Am J Pathol , vol.164 , pp. 395-407
    • Dinsdale, D.1    Lee, J.C.2    Dewson, G.3
  • 21
    • 0037017399 scopus 로고    scopus 로고
    • Selective cytotoxicity of intracellular amyloid b peptide1-42 through p53 and bax in cultured primary human neurons
    • Zhang Y, McLaughlin R, Goodyer C, et al. Selective cytotoxicity of intracellular amyloid b peptide1-42 through p53 and bax in cultured primary human neurons. J Cell Biol 2002;156:519-529
    • (2002) J Cell Biol , vol.156 , pp. 519-529
    • Zhang, Y.1    McLaughlin, R.2    Goodyer, C.3
  • 22
    • 34548258322 scopus 로고    scopus 로고
    • Accelerating amyloid-beta fibrillization reduces oligomer levels and functional deficits in Alzheimer disease mouse models
    • Cheng IH, Scearce-Levie K, Legleiter J, et al. Accelerating amyloid-beta fibrillization reduces oligomer levels and functional deficits in Alzheimer disease mouse models. J Biol Chem 2007;282:23818-23828
    • (2007) J Biol Chem , vol.282 , pp. 23818-23828
    • Cheng, I.H.1    Scearce-Levie, K.2    Legleiter, J.3
  • 23
    • 9144272296 scopus 로고    scopus 로고
    • Aggressive amyloidosis in mice expressing human amyloid peptides with the Arctic mutation
    • Cheng IH, Palop JJ, Esposito LA, et al. Aggressive amyloidosis in mice expressing human amyloid peptides with the Arctic mutation. Nat Med 2004;10:1190-1192
    • (2004) Nat Med , vol.10 , pp. 1190-1192
    • Cheng, I.H.1    Palop, J.J.2    Esposito, L.A.3
  • 24
    • 0037047157 scopus 로고    scopus 로고
    • Apoptotic threshold is lowered by p53 transactivation of caspase-6
    • MacLachlan TK, El-Deiry WS. Apoptotic threshold is lowered by p53 transactivation of caspase-6. Proc Natl Acad Sci U S A 2002;99:9492-9497
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 9492-9497
    • MacLachlan, T.K.1    El-Deiry, W.S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.