Caspase-7 expanded function and intrinsic expression level underlies strain-specific brain phenotype of Caspase-3-null mice

Journal of Neuroscience

Volumn 24, Issue 44, 2004, Pages 9977-9984

  Houde, Caroline ^a   Banks, Kathleen G ^b   Coulombe, Nathalie ^c   Rasper, Dita ^c   Grimm, Erich ^c   Roy, Sophie ^a,d   Simpson, Elizabeth M ^b   Nicholson, Donald W ^a,d  

^a MCGILL UNIVERSITY   (Canada)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^c MERCK FROSST CENTRE FOR THERAPEUTIC RESEARCH   (Canada)

^d MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Apoptosis; Brain development; Caspase 3 compensation; Caspase 7; DNA fragmentation; Strain specific phenotype

Indexed keywords

CASPASE 3; CASPASE 7; DNA; DNA FRAGMENT; ENZYME INHIBITOR; PROTEIN INHIBITOR OF CASPASE ACTIVATED DNASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN DEVELOPMENT; BRAIN DISEASE; BRAIN GROWTH; CELLULAR DISTRIBUTION; DNA CLEAVAGE; ENZYME ACTIVITY; GENE ACTIVATION; GENE DELETION; GENE EXPRESSION; MOUSE; NERVE CELL; NONHUMAN; NULL ALLELE; PHENOTYPIC PLASTICITY; PRIORITY JOURNAL; STEM CELL; STRAIN DIFFERENCE;

ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; BRAIN; CASPASE 3; CASPASE 7; CASPASES; CYSTEINE ENDOPEPTIDASES; DNA FRAGMENTATION; ENZYME ACTIVATION; HUMANS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PHENOTYPE; PROTEINS; SPECIES SPECIFICITY;

EID: 7744226465     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.3356-04.2004     Document Type: Article

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