Proteolytic cleavage of polyglutamine-expanded ataxin-3 is critical for aggregation and sequestration of non-expanded ataxin-3

Human Molecular Genetics

Volumn 15, Issue 4, 2006, Pages 555-568

  Haacke, Annette ^a   Broadley, Sarah A ^a   Boteva, Raina ^b   Tzvetkov, Nikolay ^a   Hartl, F Ulrich ^a   Breuer, Peter ^a  

^a MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

^b National Center of Radiobiology and Radiation Protection Bulgaria   (Bulgaria)

Author keywords

[No Author keywords available]

Indexed keywords

ATAXIN 3; POLYGLUTAMINE;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; IN VITRO STUDY; IN VIVO STUDY; LAMELLAR BODY; MOLECULAR BIOLOGY; MOUSE; NEUROBLASTOMA CELL; NEUROPATHOLOGY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN DEGRADATION; PROTEIN LOCALIZATION; PROTEIN STRUCTURE; SPINOCEREBELLAR DEGENERATION; WILD TYPE;

AMINO ACID SEQUENCE; ANIMALS; CELL LINE; CELL LINE, TUMOR; HUMANS; INCLUSION BODIES; MACHADO-JOSEPH DISEASE; MICE; NERVE TISSUE PROTEINS; NEUROBLASTOMA; NEURONS; NUCLEAR PROTEINS; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN STRUCTURE, TERTIARY; REPRESSOR PROTEINS; SEQUENCE DELETION; TRANSCRIPTION FACTORS;

ANIMALIA; ATAXIA;

EID: 32144436256     PISSN: 09646906     EISSN: None     Source Type: Journal    
DOI: 10.1093/hmg/ddi472     Document Type: Article

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