N-acetylcysteine reverses mitochondrial dysfunctions and behavioral abnormalities in 3-nitropropionic acid-induced Huntington's disease

Neurodegenerative Diseases

Volumn 9, Issue 3, 2012, Pages 145-157

  Sandhir, Rajat ^a   Sood, Aditi ^a   Mehrotra, Arpit ^a   Kamboj, Sukhdev S ^a  

^a PANJAB UNIVERSITY   (India)

Author keywords

3 Nitropropionic acid; Huntington's disease; Mitochondria; N acetylcysteine; Neurodegeneration; Oxidative stress

Indexed keywords

3 NITROPROPIONIC ACID; ACETYLCYSTEINE; CASPASE 3; CYTOCHROME C; CYTOCHROME C OXIDASE; MANGANESE SUPEROXIDE DISMUTASE; PROTEIN P53; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE; SUCCINATE DEHYDROGENASE (UBIQUINONE); THIOL;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COGNITION; CONTROLLED STUDY; CORPUS STRIATUM; DRUG EFFECT; ENZYME ACTIVITY; ENZYME INHIBITION; FEMALE; GLIOSIS; HISTOPATHOLOGY; HUNTINGTON CHOREA; LIPID PEROXIDATION; MITOCHONDRIAL PERMEABILITY; MITOCHONDRION; MITOCHONDRION SWELLING; NERVE DEGENERATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

ACETYLCYSTEINE; ANIMALS; BEHAVIOR, ANIMAL; CASPASE 3; COGNITION; CORPUS STRIATUM; FEMALE; FREE RADICAL SCAVENGERS; HUNTINGTON DISEASE; LIPID PEROXIDATION; MITOCHONDRIA; MOTOR SKILLS; NITRO COMPOUNDS; OXIDATIVE STRESS; PROPIONIC ACIDS; RATS; RATS, WISTAR; REACTIVE OXYGEN SPECIES; SUPEROXIDE DISMUTASE; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84858998255     PISSN: 16602854     EISSN: 16602862     Source Type: Journal    
DOI: 10.1159/000334273     Document Type: Article

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