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Volumn 20, Issue 1, 2000, Pages 119-129

Excitotoxicity is required for induction of oxidative stress and apoptosis in mouse striatum by the mitochondrial toxin, 3-nitropropionic acid

Author keywords

3 Nitropropionic acid; Apoptosis; Excitotoxicity; Mitochondria; Striatum; Superoxide

Indexed keywords

3 NITROPROPIONIC ACID; 6 NITRO 7 SULFAMOYLBENZO[F]QUINOXALINE 2,3 DIONE; DIZOCILPINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT;

EID: 0033965149     PISSN: 0271678X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00004647-200001000-00016     Document Type: Article
Times cited : (115)

References (31)
  • 3
    • 0026584524 scopus 로고
    • Does impairment of energy metabolism result in excitotoxic neuronal death in neurodegenerative illnesses?
    • Beal MF (1992) Does impairment of energy metabolism result in excitotoxic neuronal death in neurodegenerative illnesses? Ann Neurol 31:119-130
    • (1992) Ann Neurol , vol.31 , pp. 119-130
    • Beal, M.F.1
  • 4
    • 0030273295 scopus 로고    scopus 로고
    • Mitochondria, free radicals, and neurodegeneration
    • Beal MF (1996) Mitochondria, free radicals, and neurodegeneration. Curr Opin Neurobiol 6:661-666
    • (1996) Curr Opin Neurobiol , vol.6 , pp. 661-666
    • Beal, M.F.1
  • 7
    • 0030008052 scopus 로고    scopus 로고
    • Superoxide production in rat hippocampal neurons: Selective imaging with hydroethidine
    • Bindokas VP, Jordan J, Lee CC, Miller RJ (1996) Superoxide production in rat hippocampal neurons: selective imaging with hydroethidine. J Neurosci 16:1324-1336
    • (1996) J Neurosci , vol.16 , pp. 1324-1336
    • Bindokas, V.P.1    Jordan, J.2    Lee, C.C.3    Miller, R.J.4
  • 8
    • 0025580503 scopus 로고
    • Attenuation of glutamate-induced neuronal swelling and toxicity in transgenic mice overexpressing human CuZn-superoxide dismutase
    • Chan PH, Chu L, Chen SF, Carlson EJ, Epstein CJ (1990) Attenuation of glutamate-induced neuronal swelling and toxicity in transgenic mice overexpressing human CuZn-superoxide dismutase. Acta Neurochir 51 (suppl):245-246
    • (1990) Acta Neurochir , vol.51 , Issue.SUPPL. , pp. 245-246
    • Chan, P.H.1    Chu, L.2    Chen, S.F.3    Carlson, E.J.4    Epstein, C.J.5
  • 9
    • 0030987928 scopus 로고    scopus 로고
    • Secondary activation of a cation conductance is responsible for NMDA toxicity in acutely isolated hippocampal neurons
    • Chen QX, Perkins KL, Choi DW, Wong RKS (1997) Secondary activation of a cation conductance is responsible for NMDA toxicity in acutely isolated hippocampal neurons. J Neurosci 17:4032-4036
    • (1997) J Neurosci , vol.17 , pp. 4032-4036
    • Chen, Q.X.1    Perkins, K.L.2    Choi, D.W.3    Wong, R.K.S.4
  • 13
    • 0026648674 scopus 로고
    • Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation
    • Gavrieli Y, Sherman Y, Ben-Sasson SA (1992) Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J Cell Biol 119:493-501
    • (1992) J Cell Biol , vol.119 , pp. 493-501
    • Gavrieli, Y.1    Sherman, Y.2    Ben-Sasson, S.A.3
  • 14
    • 0026710232 scopus 로고
    • The neuroprotective actions of 2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline (NBQX) in a rat focal ischemia model
    • Gill R, Nordholm L, Lodge D (1992) The neuroprotective actions of 2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline (NBQX) in a rat focal ischemia model. Brain Res 580:35-13
    • (1992) Brain Res , vol.580 , pp. 35-113
    • Gill, R.1    Nordholm, L.2    Lodge, D.3
  • 15
    • 0020465435 scopus 로고
    • Basal ganglia degeneration, myelin alterations, and enzyme inhibition induced in mice by the plant toxin 3-nitropropionic acid
    • Gould DH, Gustine DL (1982) Basal ganglia degeneration, myelin alterations, and enzyme inhibition induced in mice by the plant toxin 3-nitropropionic acid. Neuropathol Appl Neurobiol 8:377-393
    • (1982) Neuropathol Appl Neurobiol , vol.8 , pp. 377-393
    • Gould, D.H.1    Gustine, D.L.2
  • 16
    • 0028893492 scopus 로고
    • Superoxide dismutase delays neuronal apoptosis: A role for reactive oxygen species in programmed neuronal death
    • Greenlund LJS, Deckwerth TL, Johnson EM Jr (1995) Superoxide dismutase delays neuronal apoptosis: a role for reactive oxygen species in programmed neuronal death. Neuron 14:303-315
    • (1995) Neuron , vol.14 , pp. 303-315
    • Greenlund, L.J.S.1    Deckwerth, T.L.2    Johnson Jr., E.M.3
  • 17
    • 0029098594 scopus 로고
    • Selective inhibition of the tricarboxylic acid cycle of GABAergic neurons with 3-nitropropionic acid in vivo
    • Hassel B, Sonnewald U (1995) Selective inhibition of the tricarboxylic acid cycle of GABAergic neurons with 3-nitropropionic acid in vivo. J Neurochem 65:1184-1191
    • (1995) J Neurochem , vol.65 , pp. 1184-1191
    • Hassel, B.1    Sonnewald, U.2
  • 18
    • 0345055313 scopus 로고    scopus 로고
    • Increased sensitivity to mitochondrial toxin-induced apoptosis in neural cells expressing mutant presenilin-1 is linked to perturbed calcium homeostasis and enhanced oxyradical production
    • Keller JN, Guo Q, Holtsberg FW, Bruce-Keller AJ, Mattson MP (1998a) Increased sensitivity to mitochondrial toxin-induced apoptosis in neural cells expressing mutant presenilin-1 is linked to perturbed calcium homeostasis and enhanced oxyradical production. J Neurosci 18:4439-4450
    • (1998) J Neurosci , vol.18 , pp. 4439-4450
    • Keller, J.N.1    Guo, Q.2    Holtsberg, F.W.3    Bruce-Keller, A.J.4    Mattson, M.P.5
  • 19
    • 17344371804 scopus 로고    scopus 로고
    • Mitochondrial manganese superoxide dismutase prevents neural apoptosis and reduces ischemic brain injury: Suppression of peroxynitrite production, lipid peroxidation, and mitochondrial dysfunction
    • Keller JN, Kindy MS, Holtsberg FW, St. Clair DK, Yen H-C, Germeyer A, Steiner SM, Bruce-Keller AJ, Hutchins JB, Mattson MP (1998b) Mitochondrial manganese superoxide dismutase prevents neural apoptosis and reduces ischemic brain injury: suppression of peroxynitrite production, lipid peroxidation, and mitochondrial dysfunction. J Neurosci 18:687-697
    • (1998) J Neurosci , vol.18 , pp. 687-697
    • Keller, J.N.1    Kindy, M.S.2    Holtsberg, F.W.3    St Clair, D.K.4    Yen, H.-C.5    Germeyer, A.6    Steiner, S.M.7    Bruce-Keller, A.J.8    Hutchins, J.B.9    Mattson, M.P.10
  • 20
    • 0017755782 scopus 로고
    • Effect of frontal cortex ablation on striatal glutamic acid level in rat
    • Kim JS, Hasller R, Hau P, Paik KS (1977) Effect of frontal cortex ablation on striatal glutamic acid level in rat. Brain Res 132:370-374
    • (1977) Brain Res , vol.132 , pp. 370-374
    • Kim, J.S.1    Hasller, R.2    Hau, P.3    Paik, K.S.4
  • 21
    • 0030934087 scopus 로고    scopus 로고
    • DNA fragmentation and prolonged expression of c-fos, c-jun, and hsp70 in kainic acid-induced neuronal cell death in transgenic mice overexpressing human CuZn-superoxide dismutase
    • Kondo T, Sharp FR, Honkaniemi J, Mikawa S, Epstein CJ, Chan PH (1997) DNA fragmentation and prolonged expression of c-fos, c-jun, and hsp70 in kainic acid-induced neuronal cell death in transgenic mice overexpressing human CuZn-superoxide dismutase. J Cereb Blood Flow Metab 17:241-256
    • (1997) J Cereb Blood Flow Metab , vol.17 , pp. 241-256
    • Kondo, T.1    Sharp, F.R.2    Honkaniemi, J.3    Mikawa, S.4    Epstein, C.J.5    Chan, P.H.6
  • 22
    • 0030916669 scopus 로고    scopus 로고
    • The proto-oncogene Bcl-2 and its role in regulating apoptosis.
    • Erratum in Nat Med 3:934, 1997
    • Kroemer G (1997) The proto-oncogene Bcl-2 and its role in regulating apoptosis. [Erratum in Nat Med 3:934, 1997] Nat Med 3:614-620
    • (1997) Nat Med , vol.3 , pp. 614-620
    • Kroemer, G.1
  • 23
    • 0026357457 scopus 로고
    • 3-Nitropropionic acid-exogenous animal neurotoxin and possible human striatal toxin
    • Ludolph AC, He F, Spencer PS, Hammerstad J, Sabri M (1991) 3-Nitropropionic acid-exogenous animal neurotoxin and possible human striatal toxin. Can J Neurol Sci 18:492-498
    • (1991) Can J Neurol Sci , vol.18 , pp. 492-498
    • Ludolph, A.C.1    He, F.2    Spencer, P.S.3    Hammerstad, J.4    Sabri, M.5
  • 24
    • 0031974368 scopus 로고    scopus 로고
    • Mitochondrial susceptibility to oxidative stress exacerbates cerebral infarction that follows permanent focal cerebral ischemia in mutant mice with manganese superoxide dismutase deficiency
    • Murakami K, Kondo T, Kawase M, Li Y, Sato S, Chen SF, Chan PH (1998) Mitochondrial susceptibility to oxidative stress exacerbates cerebral infarction that follows permanent focal cerebral ischemia in mutant mice with manganese superoxide dismutase deficiency. J Neurosci 18:205-213
    • (1998) J Neurosci , vol.18 , pp. 205-213
    • Murakami, K.1    Kondo, T.2    Kawase, M.3    Li, Y.4    Sato, S.5    Chen, S.F.6    Chan, P.H.7
  • 26
    • 0023895734 scopus 로고
    • Glutamate becomes neurotoxic via the N-methyl-D-aspartate receptor when intracellular energy levels are reduced
    • Novelli A, Reilly JA, Lysko PG, Henneberry RC (1988) Glutamate becomes neurotoxic via the N-methyl-D-aspartate receptor when intracellular energy levels are reduced. Brain Res 451:205-212
    • (1988) Brain Res , vol.451 , pp. 205-212
    • Novelli, A.1    Reilly, J.A.2    Lysko, P.G.3    Henneberry, R.C.4
  • 27
    • 0030946503 scopus 로고    scopus 로고
    • Mechanisms of cell death induced by the mitochondrial toxin 3-nitropropionic acid: Acute excitotoxic necrosis and delayed apoptosis
    • Pang Z, Geddes JW (1997) Mechanisms of cell death induced by the mitochondrial toxin 3-nitropropionic acid: acute excitotoxic necrosis and delayed apoptosis. J Neurosci 17:3064-3073
    • (1997) J Neurosci , vol.17 , pp. 3064-3073
    • Pang, Z.1    Geddes, J.W.2
  • 30
    • 0029953084 scopus 로고    scopus 로고
    • Extracellular striatal dopamine and glutamate after decortication and kainate receptor stimulation, as measured by microdialysis
    • Smolders I, Sarre S, Vanhaesendonck C, Ebinger G, Michotte Y (1996) Extracellular striatal dopamine and glutamate after decortication and kainate receptor stimulation, as measured by microdialysis. J Neurochem 66:2373-2380
    • (1996) J Neurochem , vol.66 , pp. 2373-2380
    • Smolders, I.1    Sarre, S.2    Vanhaesendonck, C.3    Ebinger, G.4    Michotte, Y.5
  • 31
    • 0029550090 scopus 로고
    • Relative vulnerability of dopamine and GABA neurons in mesencephalic culture to inhibition of succinate dehydrogenase by malonate and 3-nitropropionic acid and protection by NMDA receptor blockade
    • Zeevalk GD, Derr-Yellin E, Nicklas WJ (1995) Relative vulnerability of dopamine and GABA neurons in mesencephalic culture to inhibition of succinate dehydrogenase by malonate and 3-nitropropionic acid and protection by NMDA receptor blockade. J Pharmacol Exp Ther 275:1124-1130
    • (1995) J Pharmacol Exp Ther , vol.275 , pp. 1124-1130
    • Zeevalk, G.D.1    Derr-Yellin, E.2    Nicklas, W.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.