메뉴 건너뛰기




Volumn 29, Issue 4, 2004, Pages 729-733

Increased Formation of Reactive Oxygen Species, but No Changes in Glutathione Peroxidase Activity, in Striata of Mice Transgenic for the Huntington's Disease Mutation

Author keywords

Catalase; Glutathione peroxidase; Huntington's disease; Oxidative stress; Reactive oxygen species; Striatum; Transgenic R6 1 mice

Indexed keywords

CATALASE; DICHLOROFLUORESCEIN; GLUTATHIONE PEROXIDASE; OXYGEN RADICAL; REACTIVE OXYGEN METABOLITE;

EID: 12144288637     PISSN: 03643190     EISSN: None     Source Type: Journal    
DOI: 10.1023/B:NERE.0000018843.83770.4b     Document Type: Article
Times cited : (147)

References (24)
  • 2
    • 0038478782 scopus 로고    scopus 로고
    • Huntington's disease: New hope for therapeutics
    • McMurray, C. T. 2001. Huntington's disease: New hope for therapeutics. Trends Neurosci. 24:S32-S38.
    • (2001) Trends Neurosci. , vol.24
    • McMurray, C.T.1
  • 3
    • 0027480960 scopus 로고
    • A novel gene containing trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes
    • The Huntington's Disease Collaborative Group. 1993. A novel gene containing trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. Cell 72:971-983.
    • (1993) Cell , vol.72 , pp. 971-983
  • 5
    • 0032897760 scopus 로고    scopus 로고
    • Impaired synaptic plasticity in mice carrying the Huntington's disease mutation
    • Usdin, M. T., Shelbourne, P. F., Myers, R. M., and Madison, D. V. 1999. Impaired synaptic plasticity in mice carrying the Huntington's disease mutation. Hum. Mol. Genet. 8:839-846.
    • (1999) Hum. Mol. Genet. , vol.8 , pp. 839-846
    • Usdin, M.T.1    Shelbourne, P.F.2    Myers, R.M.3    Madison, D.V.4
  • 6
    • 0034237719 scopus 로고    scopus 로고
    • Energetics in the pathogenesis of neurodegenerative diseases
    • Beal, M. F. 2000. Energetics in the pathogenesis of neurodegenerative diseases. Trends Neurosci. 23:298-304.
    • (2000) Trends Neurosci. , vol.23 , pp. 298-304
    • Beal, M.F.1
  • 7
    • 0030919567 scopus 로고    scopus 로고
    • Oxidative damage and metabolic dysfunction in Huntington's disease: Selective vulnerability of the basal ganglia
    • Browne, S. E., Bowling, A. C., MacGarvey, U., Baik, M. J., Berger, S. C., Muqit, M. M., Bird, E. D., and Beal, M. F. 1997. Oxidative damage and metabolic dysfunction in Huntington's disease: Selective vulnerability of the basal ganglia. Ann. Neurol. 41:646-653.
    • (1997) Ann. Neurol. , vol.41 , pp. 646-653
    • Browne, S.E.1    Bowling, A.C.2    MacGarvey, U.3    Baik, M.J.4    Berger, S.C.5    Muqit, M.M.6    Bird, E.D.7    Beal, M.F.8
  • 10
    • 0342635463 scopus 로고    scopus 로고
    • Striatal oxidative damage parallels the expression of a neurological phenotype in mice transgenic for the mutation of Huntington's disease
    • Pérez-Severiano, F., Ríos, C., and Segovia, J. 2000. Striatal oxidative damage parallels the expression of a neurological phenotype in mice transgenic for the mutation of Huntington's disease. Brain Res. 862:234-237.
    • (2000) Brain Res. , vol.862 , pp. 234-237
    • Pérez-Severiano, F.1    Ríos, C.2    Segovia, J.3
  • 12
    • 0037183717 scopus 로고    scopus 로고
    • Age-dependent changes in nitric oxide synthase activity and protein expression in striata of mice transgenic for the Huntington's disease mutation
    • Pérez-Severiano, F., Escalante, B., Vergara, P., Ríos, C., and Segovia, J. 2002. Age-dependent changes in nitric oxide synthase activity and protein expression in striata of mice transgenic for the Huntington's disease mutation. Brain Res. 951:36-42.
    • (2002) Brain Res. , vol.951 , pp. 36-42
    • Pérez-Severiano, F.1    Escalante, B.2    Vergara, P.3    Ríos, C.4    Segovia, J.5
  • 13
    • 0036282378 scopus 로고    scopus 로고
    • Transgenic model for the study of oxidative damage in Huntington's disease
    • Segovia, J. 2002. Transgenic model for the study of oxidative damage in Huntington's disease. Methods Enzymol. 353:365-373.
    • (2002) Methods Enzymol. , vol.353 , pp. 365-373
    • Segovia, J.1
  • 14
    • 0026483404 scopus 로고
    • Reactive oxygen species formation as a biomarker of methylmercury and trimethyltin neurotoxicity
    • Ali, S. F., LeBel, C. P., and Bondy, S. C. 1992. Reactive oxygen species formation as a biomarker of methylmercury and trimethyltin neurotoxicity. Neurotoxicology 13:637-648.
    • (1992) Neurotoxicology , vol.13 , pp. 637-648
    • Ali, S.F.1    LeBel, C.P.2    Bondy, S.C.3
  • 15
    • 0016170551 scopus 로고
    • Effect of dietary selenium on erythrocyte and liver glutathione peroxidase in the rat
    • Hafeman, D. G., Sunde, R. A., and Hoekstra, W. G. 1974. Effect of dietary selenium on erythrocyte and liver glutathione peroxidase in the rat. J. Nutr. 104:580-587.
    • (1974) J. Nutr. , vol.104 , pp. 580-587
    • Hafeman, D.G.1    Sunde, R.A.2    Hoekstra, W.G.3
  • 18
    • 0033993641 scopus 로고    scopus 로고
    • Mice deficient in cellular glutathione peroxidase show increased vulnerability to malonate, 3-nitropropionic acid, and 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine
    • Klivenyi, P., Andreassen, O. A., Ferrante, R. J., Dedeoglu, A., Mueller, G., Lancelot, E., Bogdanov, M., Andersen, J. K., Jiang, D., and Beal, M. F. 2000. Mice deficient in cellular glutathione peroxidase show increased vulnerability to malonate, 3-nitropropionic acid, and 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine. J. Neurosci. 20:1-7.
    • (2000) J. Neurosci. , vol.20 , pp. 1-7
    • Klivenyi, P.1    Andreassen, O.A.2    Ferrante, R.J.3    Dedeoglu, A.4    Mueller, G.5    Lancelot, E.6    Bogdanov, M.7    Andersen, J.K.8    Jiang, D.9    Beal, M.F.10
  • 19
    • 0022665705 scopus 로고
    • Brain glutathione peroxidase in neurodegenerative disorders
    • Kish, S. J., Morito, C. L., and Hornykiewicz, O. 1986. Brain glutathione peroxidase in neurodegenerative disorders. Neurochem. Pathol. 4:23-28.
    • (1986) Neurochem. Pathol. , vol.4 , pp. 23-28
    • Kish, S.J.1    Morito, C.L.2    Hornykiewicz, O.3
  • 20
    • 0034237453 scopus 로고    scopus 로고
    • Quinolinic acid lesion induces changes in rat striatal glutathione metabolism
    • Cruz-Aguado, R., Francis-Turner, L., Díaz, C. M., and Antúnez, I. 2000. Quinolinic acid lesion induces changes in rat striatal glutathione metabolism. Neurochem. Int. 37:53-60.
    • (2000) Neurochem. Int. , vol.37 , pp. 53-60
    • Cruz-Aguado, R.1    Francis-Turner, L.2    Díaz, C.M.3    Antúnez, I.4
  • 22
    • 0032189894 scopus 로고    scopus 로고
    • Enhanced cellular glutathione peroxidase immunoreactivity in activated astrocytes and in microglia during excitotoxin induced neurodegeneration
    • Lindenau, J., Noack, H., Asayama, K., and Wolf, G. 1998. Enhanced cellular glutathione peroxidase immunoreactivity in activated astrocytes and in microglia during excitotoxin induced neurodegeneration. Glia 24:252-256.
    • (1998) Glia , vol.24 , pp. 252-256
    • Lindenau, J.1    Noack, H.2    Asayama, K.3    Wolf, G.4
  • 23
    • 0034646457 scopus 로고    scopus 로고
    • Mammalian thioredoxin reductase: Oxidation of the C-terminal cysteine/selenocysteine active site forms a thioselenide, and replacement of selenium with sulfur markedly reduces catalytic activity
    • Lee, S. R., Bar-Noy, S., Kwon, J., Levine, R. L., Stadtman, T. C., and Rhee, S. G. 2000. Mammalian thioredoxin reductase: Oxidation of the C-terminal cysteine/selenocysteine active site forms a thioselenide, and replacement of selenium with sulfur markedly reduces catalytic activity. Proc. Natl. Acad. Sci. USA 97:2521-2526.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 2521-2526
    • Lee, S.R.1    Bar-Noy, S.2    Kwon, J.3    Levine, R.L.4    Stadtman, T.C.5    Rhee, S.G.6
  • 24
    • 0002508819 scopus 로고
    • Protection against oxygen radicals in biological systems: The superoxide theory of oxygen toxicity
    • Halliwell, B., and Gutteridge, J. M. C. (eds.), Clarendon Press, Oxford
    • Halliwell, B., and Gutteridge, J. M. C. 1985. Protection against oxygen radicals in biological systems: The superoxide theory of oxygen toxicity. Pages 68-138, in Halliwell, B., and Gutteridge, J. M. C. (eds.), Free Radicals in Biology and Medicine, Clarendon Press, Oxford.
    • (1985) Free Radicals in Biology and Medicine , pp. 68-138
    • Halliwell, B.1    Gutteridge, J.M.C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.