-
2
-
-
0038478782
-
Huntington's disease: New hope for therapeutics
-
McMurray, C. T. 2001. Huntington's disease: New hope for therapeutics. Trends Neurosci. 24:S32-S38.
-
(2001)
Trends Neurosci.
, vol.24
-
-
McMurray, C.T.1
-
3
-
-
0027480960
-
A novel gene containing trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes
-
The Huntington's Disease Collaborative Group. 1993. A novel gene containing trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. Cell 72:971-983.
-
(1993)
Cell
, vol.72
, pp. 971-983
-
-
-
4
-
-
16044373842
-
Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice
-
Mangiarini, L., Sathasivam, K., Seller, M., Cozens, B., Harper, A., Hetherington, C., Lawton, M., Trottier, Y., Lehrach, H., Davies, S. W., and Bates, G. P. 1996. Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice. Cell 87:493-506.
-
(1996)
Cell
, vol.87
, pp. 493-506
-
-
Mangiarini, L.1
Sathasivam, K.2
Seller, M.3
Cozens, B.4
Harper, A.5
Hetherington, C.6
Lawton, M.7
Trottier, Y.8
Lehrach, H.9
Davies, S.W.10
Bates, G.P.11
-
5
-
-
0032897760
-
Impaired synaptic plasticity in mice carrying the Huntington's disease mutation
-
Usdin, M. T., Shelbourne, P. F., Myers, R. M., and Madison, D. V. 1999. Impaired synaptic plasticity in mice carrying the Huntington's disease mutation. Hum. Mol. Genet. 8:839-846.
-
(1999)
Hum. Mol. Genet.
, vol.8
, pp. 839-846
-
-
Usdin, M.T.1
Shelbourne, P.F.2
Myers, R.M.3
Madison, D.V.4
-
6
-
-
0034237719
-
Energetics in the pathogenesis of neurodegenerative diseases
-
Beal, M. F. 2000. Energetics in the pathogenesis of neurodegenerative diseases. Trends Neurosci. 23:298-304.
-
(2000)
Trends Neurosci.
, vol.23
, pp. 298-304
-
-
Beal, M.F.1
-
7
-
-
0030919567
-
Oxidative damage and metabolic dysfunction in Huntington's disease: Selective vulnerability of the basal ganglia
-
Browne, S. E., Bowling, A. C., MacGarvey, U., Baik, M. J., Berger, S. C., Muqit, M. M., Bird, E. D., and Beal, M. F. 1997. Oxidative damage and metabolic dysfunction in Huntington's disease: Selective vulnerability of the basal ganglia. Ann. Neurol. 41:646-653.
-
(1997)
Ann. Neurol.
, vol.41
, pp. 646-653
-
-
Browne, S.E.1
Bowling, A.C.2
MacGarvey, U.3
Baik, M.J.4
Berger, S.C.5
Muqit, M.M.6
Bird, E.D.7
Beal, M.F.8
-
8
-
-
0027433553
-
Neurochemical and histologic characterization of striatal excitotoxic lesions produced by the mitochondrial toxin 3-nitropropionic acid
-
Beal, M. F., Brouillet E., Jenkins, B. G., Ferrante, R. J., Kowall, N. W., Miller, J. M., Storey, E., Srivastava, R., Rosen, B. R., and Bradley, T. H. 1993. Neurochemical and histologic characterization of striatal excitotoxic lesions produced by the mitochondrial toxin 3-nitropropionic acid. J. Neurosci. 13:4181-4192.
-
(1993)
J. Neurosci.
, vol.13
, pp. 4181-4192
-
-
Beal, M.F.1
Brouillet, E.2
Jenkins, B.G.3
Ferrante, R.J.4
Kowall, N.W.5
Miller, J.M.6
Storey, E.7
Srivastava, R.8
Rosen, B.R.9
Bradley, T.H.10
-
9
-
-
0033982887
-
Mitochondrial dysfunction and free radical damage in the Huntington R6/2 transgenic mouse
-
Tabrizi, S. J., Workman, J., Hart, P. E., Mangiarini, L., Mahal, A., Bates, G., Cooper, J. M., and Schapira, A. H. V. 2000. Mitochondrial dysfunction and free radical damage in the Huntington R6/2 transgenic mouse. Ann. Neurol. 47:80-86.
-
(2000)
Ann. Neurol.
, vol.47
, pp. 80-86
-
-
Tabrizi, S.J.1
Workman, J.2
Hart, P.E.3
Mangiarini, L.4
Mahal, A.5
Bates, G.6
Cooper, J.M.7
Schapira, A.H.V.8
-
10
-
-
0342635463
-
Striatal oxidative damage parallels the expression of a neurological phenotype in mice transgenic for the mutation of Huntington's disease
-
Pérez-Severiano, F., Ríos, C., and Segovia, J. 2000. Striatal oxidative damage parallels the expression of a neurological phenotype in mice transgenic for the mutation of Huntington's disease. Brain Res. 862:234-237.
-
(2000)
Brain Res.
, vol.862
, pp. 234-237
-
-
Pérez-Severiano, F.1
Ríos, C.2
Segovia, J.3
-
11
-
-
0034915234
-
Comparative analysis of superoxide dismutase activity between acute pharmacological models and a transgenic mouse model of Huntington's disease
-
Santamaría, A., Pérez-Severiano, F., Rodrí guez-Martínez, E., Maldonado, P. D., Pedraza-Chaverri, J., Ríos, C., and Segovia, J. 2001. Comparative analysis of superoxide dismutase activity between acute pharmacological models and a transgenic mouse model of Huntington's disease. Neurochem. Res. 26:419-424.
-
(2001)
Neurochem. Res.
, vol.26
, pp. 419-424
-
-
Santamaría, A.1
Pérez-Severiano, F.2
Rodrí guez-Martínez, E.3
Maldonado, P.D.4
Pedraza-Chaverri, J.5
Ríos, C.6
Segovia, J.7
-
12
-
-
0037183717
-
Age-dependent changes in nitric oxide synthase activity and protein expression in striata of mice transgenic for the Huntington's disease mutation
-
Pérez-Severiano, F., Escalante, B., Vergara, P., Ríos, C., and Segovia, J. 2002. Age-dependent changes in nitric oxide synthase activity and protein expression in striata of mice transgenic for the Huntington's disease mutation. Brain Res. 951:36-42.
-
(2002)
Brain Res.
, vol.951
, pp. 36-42
-
-
Pérez-Severiano, F.1
Escalante, B.2
Vergara, P.3
Ríos, C.4
Segovia, J.5
-
13
-
-
0036282378
-
Transgenic model for the study of oxidative damage in Huntington's disease
-
Segovia, J. 2002. Transgenic model for the study of oxidative damage in Huntington's disease. Methods Enzymol. 353:365-373.
-
(2002)
Methods Enzymol.
, vol.353
, pp. 365-373
-
-
Segovia, J.1
-
14
-
-
0026483404
-
Reactive oxygen species formation as a biomarker of methylmercury and trimethyltin neurotoxicity
-
Ali, S. F., LeBel, C. P., and Bondy, S. C. 1992. Reactive oxygen species formation as a biomarker of methylmercury and trimethyltin neurotoxicity. Neurotoxicology 13:637-648.
-
(1992)
Neurotoxicology
, vol.13
, pp. 637-648
-
-
Ali, S.F.1
LeBel, C.P.2
Bondy, S.C.3
-
15
-
-
0016170551
-
Effect of dietary selenium on erythrocyte and liver glutathione peroxidase in the rat
-
Hafeman, D. G., Sunde, R. A., and Hoekstra, W. G. 1974. Effect of dietary selenium on erythrocyte and liver glutathione peroxidase in the rat. J. Nutr. 104:580-587.
-
(1974)
J. Nutr.
, vol.104
, pp. 580-587
-
-
Hafeman, D.G.1
Sunde, R.A.2
Hoekstra, W.G.3
-
16
-
-
0035126132
-
Post-transcriptional control of catalase expression in garlic-treated rats
-
Pedraza-Chaverri, J., Granados-Silvestre, M. D., Medina-Campos, O. N., Maldonado, P. D., Olivares-Corichi, I. M., and Ibarra-Rubio, M. E. 2001. Post-transcriptional control of catalase expression in garlic-treated rats. Mol. Cell Biochem. 216:9-19.
-
(2001)
Mol. Cell Biochem.
, vol.216
, pp. 9-19
-
-
Pedraza-Chaverri, J.1
Granados-Silvestre, M.D.2
Medina-Campos, O.N.3
Maldonado, P.D.4
Olivares-Corichi, I.M.5
Ibarra-Rubio, M.E.6
-
17
-
-
71849104860
-
Protein measurement with the Folin-phenol reagent
-
Lowry, O. H., Rosebrough, N. J., Farr, A. L., and Randall, R. J. 1951. Protein measurement with the Folin-phenol reagent. J. Biol. Chem. 193:265-275.
-
(1951)
J. Biol. Chem.
, vol.193
, pp. 265-275
-
-
Lowry, O.H.1
Rosebrough, N.J.2
Farr, A.L.3
Randall, R.J.4
-
18
-
-
0033993641
-
Mice deficient in cellular glutathione peroxidase show increased vulnerability to malonate, 3-nitropropionic acid, and 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine
-
Klivenyi, P., Andreassen, O. A., Ferrante, R. J., Dedeoglu, A., Mueller, G., Lancelot, E., Bogdanov, M., Andersen, J. K., Jiang, D., and Beal, M. F. 2000. Mice deficient in cellular glutathione peroxidase show increased vulnerability to malonate, 3-nitropropionic acid, and 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine. J. Neurosci. 20:1-7.
-
(2000)
J. Neurosci.
, vol.20
, pp. 1-7
-
-
Klivenyi, P.1
Andreassen, O.A.2
Ferrante, R.J.3
Dedeoglu, A.4
Mueller, G.5
Lancelot, E.6
Bogdanov, M.7
Andersen, J.K.8
Jiang, D.9
Beal, M.F.10
-
19
-
-
0022665705
-
Brain glutathione peroxidase in neurodegenerative disorders
-
Kish, S. J., Morito, C. L., and Hornykiewicz, O. 1986. Brain glutathione peroxidase in neurodegenerative disorders. Neurochem. Pathol. 4:23-28.
-
(1986)
Neurochem. Pathol.
, vol.4
, pp. 23-28
-
-
Kish, S.J.1
Morito, C.L.2
Hornykiewicz, O.3
-
20
-
-
0034237453
-
Quinolinic acid lesion induces changes in rat striatal glutathione metabolism
-
Cruz-Aguado, R., Francis-Turner, L., Díaz, C. M., and Antúnez, I. 2000. Quinolinic acid lesion induces changes in rat striatal glutathione metabolism. Neurochem. Int. 37:53-60.
-
(2000)
Neurochem. Int.
, vol.37
, pp. 53-60
-
-
Cruz-Aguado, R.1
Francis-Turner, L.2
Díaz, C.M.3
Antúnez, I.4
-
21
-
-
0343114486
-
Effect of quinolinic acid on endogenous antioxidants in rat corpus striatum
-
Rodríguez-Martínez, E., Camacho, A., Maldonado, P. D., Pedraza-Chaverrí, J., Santamaría, D., Galvín-Arzate, S., and Santamaría, A. 2000. Effect of quinolinic acid on endogenous antioxidants in rat corpus striatum. Brain Res. 858:436-439.
-
(2000)
Brain Res.
, vol.858
, pp. 436-439
-
-
Rodríguez-Martínez, E.1
Camacho, A.2
Maldonado, P.D.3
Pedraza-Chaverrí, J.4
Santamaría, D.5
Galvín-Arzate, S.6
Santamaría, A.7
-
22
-
-
0032189894
-
Enhanced cellular glutathione peroxidase immunoreactivity in activated astrocytes and in microglia during excitotoxin induced neurodegeneration
-
Lindenau, J., Noack, H., Asayama, K., and Wolf, G. 1998. Enhanced cellular glutathione peroxidase immunoreactivity in activated astrocytes and in microglia during excitotoxin induced neurodegeneration. Glia 24:252-256.
-
(1998)
Glia
, vol.24
, pp. 252-256
-
-
Lindenau, J.1
Noack, H.2
Asayama, K.3
Wolf, G.4
-
23
-
-
0034646457
-
Mammalian thioredoxin reductase: Oxidation of the C-terminal cysteine/selenocysteine active site forms a thioselenide, and replacement of selenium with sulfur markedly reduces catalytic activity
-
Lee, S. R., Bar-Noy, S., Kwon, J., Levine, R. L., Stadtman, T. C., and Rhee, S. G. 2000. Mammalian thioredoxin reductase: Oxidation of the C-terminal cysteine/selenocysteine active site forms a thioselenide, and replacement of selenium with sulfur markedly reduces catalytic activity. Proc. Natl. Acad. Sci. USA 97:2521-2526.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 2521-2526
-
-
Lee, S.R.1
Bar-Noy, S.2
Kwon, J.3
Levine, R.L.4
Stadtman, T.C.5
Rhee, S.G.6
-
24
-
-
0002508819
-
Protection against oxygen radicals in biological systems: The superoxide theory of oxygen toxicity
-
Halliwell, B., and Gutteridge, J. M. C. (eds.), Clarendon Press, Oxford
-
Halliwell, B., and Gutteridge, J. M. C. 1985. Protection against oxygen radicals in biological systems: The superoxide theory of oxygen toxicity. Pages 68-138, in Halliwell, B., and Gutteridge, J. M. C. (eds.), Free Radicals in Biology and Medicine, Clarendon Press, Oxford.
-
(1985)
Free Radicals in Biology and Medicine
, pp. 68-138
-
-
Halliwell, B.1
Gutteridge, J.M.C.2
|