Structure-based redesign of GST A2-2 for enhanced catalytic efficiency with azathioprine

Chemistry and Biology

Volumn 19, Issue 3, 2012, Pages 414-421

  Zhang, Wei ^a   Modén, Olof ^a   Tars, Kaspars ^b   Mannervik, Bengt ^a,c  

^a UPPSALA UNIVERSITY   (Sweden)

^b LATVIAN BIOMEDICAL RESEARCH AND STUDY CENTRE   (Latvia)

^c STOCKHOLM UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

AZATHIOPRINE; GLUTATHIONE TRANSFERASE A2; GLUTATHIONE TRANSFERASE A2 2; UNCLASSIFIED DRUG;

CATALYSIS; DNA SEQUENCE; DRUG ACTIVITY; ENZYME ACTIVATION; ENZYME STRUCTURE; GENE MUTATION; MOLECULAR DOCKING; MUTAGENESIS; PROTEIN PURIFICATION; REVIEW; X RAY CRYSTALLOGRAPHY;

EID: 84858964863     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chembiol.2012.01.021     Document Type: Article

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