Expanding metabolism for total biosynthesis of the nonnatural amino acid L-homoalanine

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 14, 2010, Pages 6234-6239

  Zhang, Kechun ^a   Li, Han ^a   Cho, Kwang Myung ^a   Liao, James C ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Chiral chemicals; Directed evolution; Metabolic engineering; Synthetic biology

Indexed keywords

2 KETOBUTYRATE; 2 OXOGLUTARIC ACID; ALANINE; AMINOTRANSFERASE; AMMONIA; BRIVARACETAM; BUTYRIC ACID DERIVATIVE; ETHAMBUTOL; ETIRACETAM; GLUCOSE; GLUTAMATE DEHYDROGENASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; THREONINE; UNCLASSIFIED DRUG; VALINE DEHYDROGENASE;

AEROBIC METABOLISM; AMINO ACID METABOLISM; ARTICLE; BACILLUS SUBTILIS; BACTERIAL STRAIN; BACTERIUM MUTANT; BIOSYNTHESIS; CHIRALITY; COMPARATIVE STUDY; CONTROLLED STUDY; ENZYME SPECIFICITY; ESCHERICHIA COLI; METABOLIC CAPACITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

AMINATION; AMINOBUTYRIC ACIDS; BACILLUS SUBTILIS; BUTYRIC ACIDS; ESCHERICHIA COLI; GLUTAMATE DEHYDROGENASE; MODELS, MOLECULAR; MOLECULAR STRUCTURE; MUTATION; PROTEIN STRUCTURE, TERTIARY; STREPTOMYCES; SUBSTRATE SPECIFICITY;

BACILLUS SUBTILIS; ESCHERICHIA COLI;

EID: 77950899704     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0912903107     Document Type: Article

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