Directed evolution of sulfotransferases and paraoxonases by ancestral libraries

Journal of Molecular Biology

Volumn 411, Issue 4, 2011, Pages 837-853

  Alcolombri, Uria ^a   Elias, Mikael ^a   Tawfik, Dan S ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

Author keywords

cytosolic sulfotransferases; directed evolution; protein phylogeny; serum paraoxonase (PON); SULT

Indexed keywords

ARYLDIALKYLPHOSPHATASE; ARYLDIALKYLPHOSPHATASE 1; ARYLDIALKYLPHOSPHATASE 2; SULFOTRANSFERASE; XENOBIOTIC AGENT;

AMINO ACID SUBSTITUTION; ARTICLE; CRYSTALLIZATION; CYTOSOL; DETOXIFICATION; DRUG METABOLISM; ENZYME ACTIVE SITE; ENZYME MECHANISM; ENZYME METABOLISM; ENZYME PURIFICATION; ENZYME SPECIFICITY; ENZYME STRUCTURE; ENZYME SUBSTRATE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MOLECULAR EVOLUTION; MOLECULAR LIBRARY; MUTATION; NUCLEOTIDE SEQUENCE; PHYLOGENY; PRIORITY JOURNAL; PROTEIN ISOLATION; SITE DIRECTED MUTAGENESIS; STRUCTURE ANALYSIS;

EID: 80051669875     PISSN: 00222836     EISSN: 10898638     Source Type: Journal    
DOI: 10.1016/j.jmb.2011.06.037     Document Type: Article

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