-
1
-
-
0023781837
-
Topography of cognition: Parallel distributed networks in primate association cortex
-
Goldman-Rakic, P. S. Topography of cognition: parallel distributed networks in primate association cortex. Annu. Rev. Neurosci. 11, 137-156 (1988).
-
(1988)
Annu. Rev. Neurosci.
, vol.11
, pp. 137-156
-
-
Goldman-Rakic, P.S.1
-
2
-
-
0028938076
-
Cellular basis of working memory
-
Goldman-Rakic, P. S. Cellular basis of working memory. Neuron 14, 477-485 (1995).
-
(1995)
Neuron
, vol.14
, pp. 477-485
-
-
Goldman-Rakic, P.S.1
-
3
-
-
0034304940
-
The prefrontal cortex and cognitive control
-
Miller, E. K. The prefrontal cortex and cognitive control. Nature Rev. Neurosci. 1, 59-65 (2000).
-
(2000)
Nature Rev. Neurosci.
, vol.1
, pp. 59-65
-
-
Miller, E.K.1
-
4
-
-
85014275788
-
-
4th edn Academic Press, London, This book provides an authoritative and comprehensive analysis of the unique role of the PFC in cognition
-
Fuster, J. M. The Prefrontal Cortex. 4th edn (Academic Press, London, 2008). This book provides an authoritative and comprehensive analysis of the unique role of the PFC in cognition.
-
(2008)
The Prefrontal Cortex
-
-
Fuster, J.M.1
-
5
-
-
0024439790
-
Evidence for task-dependent memory dysfunction in the aged monkey
-
Rapp, P. R. & Amaral, D. G. Evidence for task-dependent memory dysfunction in the aged monkey. J. Neurosci. 9, 3568-3576 (1989).
-
(1989)
J. Neurosci.
, vol.9
, pp. 3568-3576
-
-
Rapp, P.R.1
Amaral, D.G.2
-
6
-
-
0025633754
-
Visual discrimination and reversal learning in the aged monkey (Macaca mulatta)
-
Rapp, P. R. Visual discrimination and reversal learning in the aged monkey (Macaca mulatta). Behav. Neurosci. 104, 876-884 (1990).
-
(1990)
Behav. Neurosci.
, vol.104
, pp. 876-884
-
-
Rapp, P.R.1
-
7
-
-
0030765344
-
Patterns of cognitive decline in aged rhesus monkeys
-
This paper reports a cross-sectional study of performance on a battery of multiple behavioural tasks across the lifespan of rhesus monkeys
-
Herndon, J. G., Moss, M. B., Rosene, D. L. &Killiany, R. J. Patterns of cognitive decline in aged rhesus monkeys. Behav. Brain Res. 87, 25-34 (1997). This paper reports a cross-sectional study of performance on a battery of multiple behavioural tasks across the lifespan of rhesus monkeys.
-
(1997)
Behav. Brain Res.
, vol.87
, pp. 25-34
-
-
Herndon, J.G.1
Moss, M.B.2
Rosene, D.L.3
Killiany, R.J.4
-
8
-
-
33747798319
-
Executive system dysfunction occurs as early as middle-age in the rhesus monkey
-
Moore, T. L., Killiany, R. J., Herndon, J. G., Rosene, D. L. & Moss, M. B. Executive system dysfunction occurs as early as middle-age in the rhesus monkey. Neurobiol. Aging 27, 1484-1493 (2006).
-
(2006)
Neurobiol. Aging
, vol.27
, pp. 1484-1493
-
-
Moore, T.L.1
Killiany, R.J.2
Herndon, J.G.3
Rosene, D.L.4
Moss, M.B.5
-
9
-
-
0033400984
-
Impairments in acquisition and reversals of two-choice discriminations by aged rhesus monkeys
-
Voytko, M. L. Impairments in acquisition and reversals of two-choice discriminations by aged rhesus monkeys. Neurobiol. Aging 20, 617-627 (1999).
-
(1999)
Neurobiol. Aging
, vol.20
, pp. 617-627
-
-
Voytko, M.L.1
-
10
-
-
9644265444
-
Short- and long-term spatial delayed response performance across the lifespan
-
Lyons-Warren, A., Lillie, R. & Hershey, T. Short- and long-term spatial delayed response performance across the lifespan. Dev. Neuropsychol. 26, 661-678 (2004).
-
(2004)
Dev. Neuropsychol.
, vol.26
, pp. 661-678
-
-
Lyons-Warren, A.1
Lillie, R.2
Hershey, T.3
-
11
-
-
77955278629
-
Dynamic network connectivity: A new form of neuroplasticity
-
This paper summarizes research on mechanisms of plasticity, which underlie spatial working memory function in the PFC
-
Arnsten, A. F., Paspalas, C. D., Gamo, N. J., Yang, Y. &Wang, M. Dynamic network connectivity: a new form of neuroplasticity. Trends Cogn. Sci. 14, 365-375 (2010). This paper summarizes research on mechanisms of plasticity, which underlie spatial working memory function in the PFC.
-
(2010)
Trends Cogn. Sci.
, vol.14
, pp. 365-375
-
-
Arnsten, A.F.1
Paspalas, C.D.2
Gamo, N.J.3
Yang, Y.4
Wang, M.5
-
12
-
-
0031814240
-
Feature article: Are neurons lost from the primate cerebral cortex during normal aging?
-
Peters, A., Morrison, J. H., Rosene, D. L. & Hyman, B. T. Feature article: are neurons lost from the primate cerebral cortex during normal aging? Cereb. Cortex 8, 295-300 (1998).
-
(1998)
Cereb. Cortex
, vol.8
, pp. 295-300
-
-
Peters, A.1
Morrison, J.H.2
Rosene, D.L.3
Hyman, B.T.4
-
13
-
-
2342612629
-
Memory impairment in aged primates is associated with focal death of cortical neurons and atrophy of subcortical neurons
-
Smith, D. E., Rapp, P. R., McKay, H. M., Roberts, J. A. & Tuszynski, M. H. Memory impairment in aged primates is associated with focal death of cortical neurons and atrophy of subcortical neurons. J. Neurosci. 24, 4373-4381 (2004).
-
(2004)
J. Neurosci.
, vol.24
, pp. 4373-4381
-
-
Smith, D.E.1
Rapp, P.R.2
McKay, H.M.3
Roberts, J.A.4
Tuszynski, M.H.5
-
14
-
-
40849094662
-
Age-related regional network of magnetic resonance imaging gray matter in the rhesus macaque
-
Alexander, G. E. et al. Age-related regional network of magnetic resonance imaging gray matter in the rhesus macaque. J. Neurosci. 28, 2710-2718 (2008).
-
(2008)
J. Neurosci.
, vol.28
, pp. 2710-2718
-
-
Alexander, G.E.1
-
15
-
-
79959481908
-
Volumetric correlates of spatiotemporal working and recognition memory impairment in aged rhesus monkeys
-
Shamy, J. L. et al. Volumetric correlates of spatiotemporal working and recognition memory impairment in aged rhesus monkeys. Cereb. Cortex 21, 1559-1573 (2011).
-
(2011)
Cereb. Cortex
, vol.21
, pp. 1559-1573
-
-
Shamy, J.L.1
-
16
-
-
41549167594
-
Synapses are lost during aging in the primate prefrontal cortex
-
This paper was the first quantitative electron microscopic study to report synapse loss in the rhesus monkey PFC and to show that the degree of synapse loss in layer 2/3 correlates with cognitive impairment
-
Peters, A., Sethares, C. & Luebke, J. I. Synapses are lost during aging in the primate prefrontal cortex. Neuroscience 152, 970-981 (2008). This paper was the first quantitative electron microscopic study to report synapse loss in the rhesus monkey PFC and to show that the degree of synapse loss in layer 2/3 correlates with cognitive impairment.
-
(2008)
Neuroscience
, vol.152
, pp. 970-981
-
-
Peters, A.1
Sethares, C.2
Luebke, J.I.3
-
17
-
-
77953189368
-
Selective changes in thin spine density and morphology in monkey prefrontal cortex correlate with aging-related cognitive impairment
-
Dumitriu, D. et al. Selective changes in thin spine density and morphology in monkey prefrontal cortex correlate with aging-related cognitive impairment. J. Neurosci. 30, 7507-7515 (2010).
-
(2010)
J. Neurosci.
, vol.30
, pp. 7507-7515
-
-
Dumitriu, D.1
-
18
-
-
0041357082
-
Age-related dendritic and spine changes in corticocortically projecting neurons in macaque monkeys
-
Duan, H. et al. Age-related dendritic and spine changes in corticocortically projecting neurons in macaque monkeys. Cereb. Cortex 13, 950-961 (2003).
-
(2003)
Cereb. Cortex
, vol.13
, pp. 950-961
-
-
Duan, H.1
-
19
-
-
77149125238
-
Effects of normal aging on prefrontal area 46 in the rhesus monkey
-
Luebke, J., Barbas, H. & Peters, A. Effects of normal aging on prefrontal area 46 in the rhesus monkey. Brain Res. Rev. 62, 212-232 (2010).
-
(2010)
Brain Res. Rev.
, vol.62
, pp. 212-232
-
-
Luebke, J.1
Barbas, H.2
Peters, A.3
-
20
-
-
0037074055
-
Aging and the myelinated fibers in prefrontal cortex and corpus callosum of the monkey
-
Peters, A. & Sethares, C. Aging and the myelinated fibers in prefrontal cortex and corpus callosum of the monkey. J. Comp. Neurol. 442, 277-291 (2002).
-
(2002)
J. Comp. Neurol.
, vol.442
, pp. 277-291
-
-
Peters, A.1
Sethares, C.2
-
21
-
-
59249087963
-
-
ed. Riddle, D. R. CRC Press, North Carolina
-
Peters, A. in Brain Aging: Models, Methods, and Mechanisms (ed. Riddle, D. R.) (CRC Press, North Carolina, 2007).
-
(2007)
Brain Aging: Models, Methods, and Mechanisms
-
-
Peters, A.1
-
22
-
-
15244346712
-
Increased action potential firing rates of layer 2/3 pyramidal cells in the prefrontal cortex are significantly related to cognitive performance in aged monkeys
-
Chang, Y. M., Rosene, D. L., Killiany, R. J., Mangiamele, L. A. & Luebke, J. I. Increased action potential firing rates of layer 2/3 pyramidal cells in the prefrontal cortex are significantly related to cognitive performance in aged monkeys. Cereb. Cortex 15, 409-418 (2005).
-
(2005)
Cereb. Cortex
, vol.15
, pp. 409-418
-
-
Chang, Y.M.1
Rosene, D.L.2
Killiany, R.J.3
Mangiamele, L.A.4
Luebke, J.I.5
-
23
-
-
36749031859
-
Effects of aging on the electrophysiological properties of layer 5 pyramidal cells in the monkey prefrontal cortex
-
Luebke, J. I. & Chang, Y. M. Effects of aging on the electrophysiological properties of layer 5 pyramidal cells in the monkey prefrontal cortex. Neuroscience 150, 556-562 (2007).
-
(2007)
Neuroscience
, vol.150
, pp. 556-562
-
-
Luebke, J.I.1
Chang, Y.M.2
-
24
-
-
84859483109
-
AHPin prefrontal pyramidal cells of monkeys: Relationship to cognition
-
Aug doi:10.1016/j.neurobiolaging.2010.07.002
-
AHP in prefrontal pyramidal cells of monkeys: relationship to cognition. Neurobiol. Aging 19 Aug 2010 (doi:10.1016/j.neurobiolaging.2010.07. 002).
-
(2010)
Neurobiol. Aging
, vol.19
-
-
Luebke, J.I.1
Amatrudo, J.M.2
-
25
-
-
0014768351
-
The small pyramidal neuron of the rat cerebral cortex. The perikaryon, dendrites and spines
-
Peters, A. & Kaiserman-Abramof, I. R. The small pyramidal neuron of the rat cerebral cortex. The perikaryon, dendrites and spines. Am. J. Anat. 127, 321-355 (1970).
-
(1970)
Am. J. Anat.
, vol.127
, pp. 321-355
-
-
Peters, A.1
Kaiserman-Abramof, I.R.2
-
26
-
-
0028330166
-
Dendritic spines: Cellular specializations imparting both stability and flexibility to synaptic function
-
Harris, K. M. & Kater, S. B. Dendritic spines: cellular specializations imparting both stability and flexibility to synaptic function. Annu. Rev. Neurosci. 17, 341-371 (1994).
-
(1994)
Annu. Rev. Neurosci.
, vol.17
, pp. 341-371
-
-
Harris, K.M.1
Kater, S.B.2
-
27
-
-
0035708355
-
Dendritic spine geometry is critical for AMPA receptor expression in hippocampal CA1 pyramidal neurons
-
Matsuzaki, M. et al. Dendritic spine geometry is critical for AMPA receptor expression in hippocampal CA1 pyramidal neurons. Nature Neurosci. 4, 1086-1092 (2001).
-
(2001)
Nature Neurosci.
, vol.4
, pp. 1086-1092
-
-
Matsuzaki, M.1
-
28
-
-
0038015543
-
Structure-stability-function relationships of dendritic spines
-
Kasai, H., Matsuzaki, M., Noguchi, J., Yasumatsu, N. & Nakahara, H. Structure-stability-function relationships of dendritic spines. Trends Neurosci. 26, 360-368 (2003).
-
(2003)
Trends Neurosci.
, vol.26
, pp. 360-368
-
-
Kasai, H.1
Matsuzaki, M.2
Noguchi, J.3
Yasumatsu, N.4
Nakahara, H.5
-
29
-
-
17444373481
-
Development of long-term dendritic spine stability in diverse regions of cerebral cortex
-
Zuo, Y., Lin, A., Chang, P. & Gan, W. B. Development of long-term dendritic spine stability in diverse regions of cerebral cortex. Neuron 46, 181-189 (2005).
-
(2005)
Neuron
, vol.46
, pp. 181-189
-
-
Zuo, Y.1
Lin, A.2
Chang, P.3
Gan, W.B.4
-
30
-
-
33745562839
-
Experience-dependent and cell-type-specific spine growth in the neocortex
-
Holtmaat, A., Wilbrecht, L., Knott, G. W., Welker, E. &Svoboda, K. Experience-dependent and cell-type-specific spine growth in the neocortex. Nature 441, 979-983 (2006).
-
(2006)
Nature
, vol.441
, pp. 979-983
-
-
Holtmaat, A.1
Wilbrecht, L.2
Knott, G.W.3
Welker, E.4
Svoboda, K.5
-
31
-
-
34249933982
-
Do thin spines learn to be mushroom spines that remember?
-
Bourne, J. & Harris, K. M. Do thin spines learn to be mushroom spines that remember? Curr. Opin. Neurobiol. 17, 381-386 (2007).
-
(2007)
Curr. Opin. Neurobiol.
, vol.17
, pp. 381-386
-
-
Bourne, J.1
Harris, K.M.2
-
32
-
-
79952198353
-
Learning rules and persistence of dendritic spines
-
Kasai, H. et al. Learning rules and persistence of dendritic spines. Eur. J. Neurosci. 32, 241-249 (2010).
-
(2010)
Eur. J. Neurosci.
, vol.32
, pp. 241-249
-
-
Kasai, H.1
-
33
-
-
0346780703
-
Differences in the expression of AMPA and NMDA receptors between axospinous perforated and nonperforated synapses are related to the configuration and size of postsynaptic densities
-
Ganeshina, O., Berry, R. W., Petralia, R. S., Nicholson, D. A. & Geinisman, Y. Differences in the expression of AMPA and NMDA receptors between axospinous perforated and nonperforated synapses are related to the configuration and size of postsynaptic densities. J. Comp. Neurol. 468, 86-95 (2004).
-
(2004)
J. Comp. Neurol.
, vol.468
, pp. 86-95
-
-
Ganeshina, O.1
Berry, R.W.2
Petralia, R.S.3
Nicholson, D.A.4
Geinisman, Y.5
-
34
-
-
33646137361
-
Distance-dependent differences in synapse number and AMPA receptor expression in hippocampal CA1 pyramidal neurons
-
Nicholson, D. A. et al. Distance-dependent differences in synapse number and AMPA receptor expression in hippocampal CA1 pyramidal neurons. Neuron 50, 431-442 (2006).
-
(2006)
Neuron
, vol.50
, pp. 431-442
-
-
Nicholson, D.A.1
-
35
-
-
59149102797
-
Axospinous synaptic subtype-specific differences in structure, size, ionotropic receptor expression, and connectivity in apical dendritic regions of rat hippocampal CA1 pyramidal neurons
-
Nicholson, D. A. & Geinisman, Y. Axospinous synaptic subtype-specific differences in structure, size, ionotropic receptor expression, and connectivity in apical dendritic regions of rat hippocampal CA1 pyramidal neurons. J. Comp. Neurol. 512, 399-418 (2009).
-
(2009)
J. Comp. Neurol.
, vol.512
, pp. 399-418
-
-
Nicholson, D.A.1
Geinisman, Y.2
-
36
-
-
40949110901
-
Developmental presence and disappearance of postsynaptically silent synapses on dendritic spines of rat layer 2/3 pyramidal neurons
-
Busetto, G., Higley, M. J. & Sabatini, B. L. Developmental presence and disappearance of postsynaptically silent synapses on dendritic spines of rat layer 2/3 pyramidal neurons. J. Physiol. 586, 1519-1527 (2008).
-
(2008)
J. Physiol.
, vol.586
, pp. 1519-1527
-
-
Busetto, G.1
Higley, M.J.2
Sabatini, B.L.3
-
37
-
-
58849093289
-
Rapid functional maturation of nascent dendritic spines
-
Zito, K., Scheuss, V., Knott, G., Hill, T. & Svoboda, K. Rapid functional maturation of nascent dendritic spines. Neuron 61, 247-258 (2009).
-
(2009)
Neuron
, vol.61
, pp. 247-258
-
-
Zito, K.1
Scheuss, V.2
Knott, G.3
Hill, T.4
Svoboda, K.5
-
38
-
-
80052410549
-
High-throughput, detailed, cell-specific neuroanatomy of dendritic spines using microinjection and confocal microscopy
-
Dumitriu, D., Rodriguez, A. & Morrison, J. H. High-throughput, detailed, cell-specific neuroanatomy of dendritic spines using microinjection and confocal microscopy. Nature Protoc. 6, 1391-1411 (2011).
-
(2011)
Nature Protoc.
, vol.6
, pp. 1391-1411
-
-
Dumitriu, D.1
Rodriguez, A.2
Morrison, J.H.3
-
39
-
-
34248652917
-
Rayburst sampling, an algorithm for automated three-dimensional shape analysis from laser scanning microscopy images
-
Rodriguez, A., Ehlenberger, D. B., Hof, P. R. & Wearne, S. L. Rayburst sampling, an algorithm for automated three-dimensional shape analysis from laser scanning microscopy images. Nature Protoc. 1, 2152-2161 (2006).
-
(2006)
Nature Protoc.
, vol.1
, pp. 2152-2161
-
-
Rodriguez, A.1
Ehlenberger, D.B.2
Hof, P.R.3
Wearne, S.L.4
-
40
-
-
44349154735
-
Automated three-dimensional detection and shape classification of dendritic spines from fluorescence microscopy images
-
Rodriguez, A., Ehlenberger, D. B., Dickstein, D. L., Hof, P. R. & Wearne, S. L. Automated three-dimensional detection and shape classification of dendritic spines from fluorescence microscopy images. PLoS ONE 3, e1997 (2008).
-
(2008)
PLoS ONE
, vol.3
-
-
Rodriguez, A.1
Ehlenberger, D.B.2
Dickstein, D.L.3
Hof, P.R.4
Wearne, S.L.5
-
41
-
-
77952400307
-
Interactive effects of stress and aging on structural plasticity in the prefrontal cortex
-
Bloss, E. B., Janssen, W. G., McEwen, B. S. &Morrison, J. H. Interactive effects of stress and aging on structural plasticity in the prefrontal cortex. J. Neurosci. 30, 6726-6731 (2010).
-
(2010)
J. Neurosci.
, vol.30
, pp. 6726-6731
-
-
Bloss, E.B.1
Janssen, W.G.2
McEwen, B.S.3
Morrison, J.H.4
-
42
-
-
79957651404
-
Evidence for reduced experience-dependent dendritic spine plasticity in the aging prefrontal cortex
-
Ageing in rats is associated with impaired dendritic spine recovery in the PFC after chronic stress. This supports the view that in addition to age-related changes in spine density and morphology, ageing is also associated with a reduction in the plasticity of dendritic spines
-
Bloss, E. B. et al. Evidence for reduced experience-dependent dendritic spine plasticity in the aging prefrontal cortex. J. Neurosci. 31, 7831-7839 (2011). Ageing in rats is associated with impaired dendritic spine recovery in the PFC after chronic stress. This supports the view that in addition to age-related changes in spine density and morphology, ageing is also associated with a reduction in the plasticity of dendritic spines.
-
(2011)
J. Neurosci.
, vol.31
, pp. 7831-7839
-
-
Bloss, E.B.1
-
43
-
-
5644297023
-
Environmental influences on cognitive and brain plasticity during aging
-
Kramer, A. F., Bherer, L., Colcombe, S. J., Dong, W. &Greenough, W. T. Environmental influences on cognitive and brain plasticity during aging. J. Gerontol. A Biol. Sci. Med. Sci. 59, M940-M957 (2004).
-
(2004)
J. Gerontol. A Biol. Sci. Med. Sci.
, vol.59
-
-
Kramer, A.F.1
Bherer, L.2
Colcombe, S.J.3
Dong, W.4
Greenough, W.T.5
-
44
-
-
50949104956
-
Expertise and aging: Maintaining skills through the lifespan
-
Horton S., Baker, J. & Schorer J. Expertise and aging: maintaining skills through the lifespan. Eur. Rev. Aging Phys. Act. 5, 89-96 (2008).
-
(2008)
Eur. Rev. Aging Phys. Act.
, vol.5
, pp. 89-96
-
-
Horton, S.1
Baker, J.2
Schorer, J.3
-
45
-
-
80051677168
-
Neuronal basis of age-related working memory decline
-
This paper directly demonstrates a neurophysiological mechanism for age-related impairments in prefrontal-dependent spatial working memory: a reduction in the firing rate of cells that are active during the memory delay. This physiological deficit could be reversed by inhibition of cAMP signalling, or by blocking particular subtypes of potassium channels
-
Wang, M. et al. Neuronal basis of age-related working memory decline. Nature 476, 210-213 (2011). This paper directly demonstrates a neurophysiological mechanism for age-related impairments in prefrontal-dependent spatial working memory: a reduction in the firing rate of cells that are active during the memory delay. This physiological deficit could be reversed by inhibition of cAMP signalling, or by blocking particular subtypes of potassium channels.
-
(2011)
Nature
, vol.476
, pp. 210-213
-
-
Wang, M.1
-
46
-
-
34147105096
-
α2A-adrenoceptors strengthen working memory networks by inhibiting cAMP-HCN channel signaling in prefrontal cortex
-
Wang, M. et al. α2A-adrenoceptors strengthen working memory networks by inhibiting cAMP-HCN channel signaling in prefrontal cortex. Cell 129, 397-410 (2007).
-
(2007)
Cell
, vol.129
, pp. 397-410
-
-
Wang, M.1
-
47
-
-
0035036637
-
Properties of hyperpolarization-activated pacemaker current defined by coassembly of HCN1 and HCN2 subunits and basal modulation by cyclic nucleotide
-
Chen, S., Wang, J. & Siegelbaum, S. A. Properties of hyperpolarization-activated pacemaker current defined by coassembly of HCN1 and HCN2 subunits and basal modulation by cyclic nucleotide. J. Gen. Physiol. 117, 491-504 (2001).
-
(2001)
J. Gen. Physiol.
, vol.117
, pp. 491-504
-
-
Chen, S.1
Wang, J.2
Siegelbaum, S.A.3
-
48
-
-
0024239064
-
The alpha-2 adrenergic agonist guanfacine improves memory in aged monkeys without sedative or hypotensive side effects: Evidence for alpha-2 receptor subtypes
-
Arnsten, A. F., Cai, J. X. & Goldman-Rakic, P. S. The alpha-2 adrenergic agonist guanfacine improves memory in aged monkeys without sedative or hypotensive side effects: evidence for alpha-2 receptor subtypes. J. Neurosci. 8, 4287-4298 (1988).
-
(1988)
J. Neurosci.
, vol.8
, pp. 4287-4298
-
-
Arnsten, A.F.1
Cai, J.X.2
Goldman-Rakic, P.S.3
-
49
-
-
0036641819
-
Rodent models of prefrontal cortical function
-
Brown, V. J. & Bowman, E. M. Rodent models of prefrontal cortical function. Trends Neurosci. 25, 340-343 (2002).
-
(2002)
Trends Neurosci.
, vol.25
, pp. 340-343
-
-
Brown, V.J.1
Bowman, E.M.2
-
50
-
-
0028907956
-
Do rats have prefrontal cortex?
-
Preuss, T. Do rats have prefrontal cortex? J. Cogn. Neurosci. 7, 1-24 (1995).
-
(1995)
J. Cogn. Neurosci.
, vol.7
, pp. 1-24
-
-
Preuss, T.1
-
51
-
-
0036667081
-
Aged rats are impaired on an attentional set-shifting task sensitive to medial frontal cortex damage in young rats
-
Barense, M. D., Fox, M. T. & Baxter, M. G. Aged rats are impaired on an attentional set-shifting task sensitive to medial frontal cortex damage in young rats. Learn. Mem. 9, 191-201 (2002).
-
(2002)
Learn. Mem.
, vol.9
, pp. 191-201
-
-
Barense, M.D.1
Fox, M.T.2
Baxter, M.G.3
-
52
-
-
0242460552
-
Dysregulation of protein kinase a signaling in the aged prefrontal cortex: New strategy for treating age-related cognitive decline
-
Ramos, B. P. et al. Dysregulation of protein kinase a signaling in the aged prefrontal cortex: new strategy for treating age-related cognitive decline. Neuron 40, 835-845 (2003).
-
(2003)
Neuron
, vol.40
, pp. 835-845
-
-
Ramos, B.P.1
-
53
-
-
0242689354
-
Activation of cAMP-dependent protein kinase A in prefrontal cortex impairs working memory performance
-
Taylor, J. R., Birnbaum, S., Ubriani, R. & Arnsten, A. F. Activation of cAMP-dependent protein kinase A in prefrontal cortex impairs working memory performance. J. Neurosci. 19, RC23 (1999).
-
(1999)
J. Neurosci.
, vol.19
-
-
Taylor, J.R.1
Birnbaum, S.2
Ubriani, R.3
Arnsten, A.F.4
-
54
-
-
84856690726
-
Aging reduces total neuron number in the dorsal component of the rodent prefrontal cortex
-
Oct doi:10.1002/cne.22790
-
Stranahan, A. M., Jiam, N. T., Stocker, A. M. &Gallagher, M. Aging reduces total neuron number in the dorsal component of the rodent prefrontal cortex. J. Comp. Neurol. 20 Oct 2011 (doi:10.1002/cne.22790).
-
(2011)
J. Comp. Neurol.
, vol.20
-
-
Stranahan, A.M.1
Jiam, N.T.2
Stocker, A.M.3
Gallagher, M.4
-
55
-
-
33747070540
-
Stress-induced alterations in prefrontal cortical dendritic morphology predict selective impairments in perceptual attentional set-shifting
-
Liston, C. et al. Stress-induced alterations in prefrontal cortical dendritic morphology predict selective impairments in perceptual attentional set-shifting. J. Neurosci. 26, 7870-7874 (2006).
-
(2006)
J. Neurosci.
, vol.26
, pp. 7870-7874
-
-
Liston, C.1
-
56
-
-
1642421311
-
Chronic behavioral stress induces apical dendritic reorganization in pyramidal neurons of the medial prefrontal cortex
-
Radley, J. J. et al. Chronic behavioral stress induces apical dendritic reorganization in pyramidal neurons of the medial prefrontal cortex. Neuroscience 125, 1-6 (2004).
-
(2004)
Neuroscience
, vol.125
, pp. 1-6
-
-
Radley, J.J.1
-
57
-
-
38949113706
-
Repeated stress alters dendritic spine morphology in the rat medial prefrontal cortex
-
Radley, J. J. et al. Repeated stress alters dendritic spine morphology in the rat medial prefrontal cortex. J. Comp. Neurol. 507, 1141-1150 (2008).
-
(2008)
J. Comp. Neurol.
, vol.507
, pp. 1141-1150
-
-
Radley, J.J.1
-
58
-
-
3442877504
-
Chronic stress alters dendritic morphology in rat medial prefrontal cortex
-
Cook, S. C. & Wellman, C. L. Chronic stress alters dendritic morphology in rat medial prefrontal cortex. J. Neurobiol. 60, 236-248 (2004).
-
(2004)
J. Neurobiol.
, vol.60
, pp. 236-248
-
-
Cook, S.C.1
Wellman, C.L.2
-
59
-
-
23444432520
-
Reversibility of apical dendritic retraction in the rat medial prefrontal cortex following repeated stress
-
Radley, J. J. et al. Reversibility of apical dendritic retraction in the rat medial prefrontal cortex following repeated stress. Exp. Neurol. 196, 199-203 (2005).
-
(2005)
Exp. Neurol.
, vol.196
, pp. 199-203
-
-
Radley, J.J.1
-
60
-
-
70349731916
-
Structural and functional alterations to rat medial prefrontal cortex following chronic restraint stress and recovery
-
Goldwater, D. S. et al. Structural and functional alterations to rat medial prefrontal cortex following chronic restraint stress and recovery. Neuroscience 164, 798-808 (2009).
-
(2009)
Neuroscience
, vol.164
, pp. 798-808
-
-
Goldwater, D.S.1
-
61
-
-
0021232733
-
Severe tactual as well as visual memory deficits follow combined removal of the amygdala and hippocampus in monkeys
-
Murray, E. A. & Mishkin, M. Severe tactual as well as visual memory deficits follow combined removal of the amygdala and hippocampus in monkeys. J. Neurosci. 4, 2565-2580 (1984).
-
(1984)
J. Neurosci.
, vol.4
, pp. 2565-2580
-
-
Murray, E.A.1
Mishkin, M.2
-
62
-
-
0027141313
-
Effects on visual recognition of combined and separate ablations of the entorhinal and perirhinal cortex in rhesus monkeys
-
Meunier, M., Bachevalier, J., Mishkin, M. &Murray, E. A. Effects on visual recognition of combined and separate ablations of the entorhinal and perirhinal cortex in rhesus monkeys. J. Neurosci. 13, 5418-5432 (1993).
-
(1993)
J. Neurosci.
, vol.13
, pp. 5418-5432
-
-
Meunier, M.1
Bachevalier, J.2
Mishkin, M.3
Murray, E.A.4
-
63
-
-
0035098414
-
Opposite relationship of hippocampal and rhinal cortex damage to delayed nonmatching-to-sample deficits in monkeys
-
Baxter, M. G. & Murray, E. A. Opposite relationship of hippocampal and rhinal cortex damage to delayed nonmatching-to-sample deficits in monkeys. Hippocampus 11, 61-71 (2001).
-
(2001)
Hippocampus
, vol.11
, pp. 61-71
-
-
Baxter, M.G.1
Murray, E.A.2
-
64
-
-
0019957779
-
Place navigation impaired in rats with hippocampal lesions
-
Morris, R. G., Garrud, P., Rawlins, J. N. & O'Keefe, J. Place navigation impaired in rats with hippocampal lesions. Nature 297, 681-683 (1982).
-
(1982)
Nature
, vol.297
, pp. 681-683
-
-
Morris, R.G.1
Garrud, P.2
Rawlins, J.N.3
O'Keefe, J.4
-
65
-
-
0027723549
-
Animal models of normal aging: Relationship between cognitive decline and markers in hippocampal circuitry
-
Gallagher, M. & Nicolle, M. M. Animal models of normal aging: Relationship between cognitive decline and markers in hippocampal circuitry. Behav. Brain Res. 57, 155-162 (1993).
-
(1993)
Behav. Brain Res.
, vol.57
, pp. 155-162
-
-
Gallagher, M.1
Nicolle, M.M.2
-
66
-
-
0031808924
-
Episodic and declarative memory: Role of the hippocampus
-
Tulving, E. & Markowitsch, H. J. Episodic and declarative memory: role of the hippocampus. Hippocampus 8, 198-204 (1998).
-
(1998)
Hippocampus
, vol.8
, pp. 198-204
-
-
Tulving, E.1
Markowitsch, H.J.2
-
67
-
-
54049122688
-
Cognitive aging: A common decline of episodic recollection and spatial memory in rats
-
Estimates of hippocampal-dependent episodic recollection were derived from performance in an olfactory recognition task in young and aged rats. These correlated strongly with spatial memory in the water maze: aged rats with spatial memory impairments demonstrated a selective impairment in episodic recollection
-
Robitsek, R. J., Fortin, N. J., Koh, M. T., Gallagher, M. & Eichenbaum, H. Cognitive aging: a common decline of episodic recollection and spatial memory in rats. J. Neurosci. 28, 8945-8954 (2008). Estimates of hippocampal-dependent episodic recollection were derived from performance in an olfactory recognition task in young and aged rats. These correlated strongly with spatial memory in the water maze: aged rats with spatial memory impairments demonstrated a selective impairment in episodic recollection.
-
(2008)
J. Neurosci.
, vol.28
, pp. 8945-8954
-
-
Robitsek, R.J.1
Fortin, N.J.2
Koh, M.T.3
Gallagher, M.4
Eichenbaum, H.5
-
68
-
-
77958114837
-
"I've seen it all before": Explaining age-related impairments in object recognition
-
Theoretical comment on Burke. et al. (2010)
-
Baxter, M. G. "I've seen it all before": explaining age-related impairments in object recognition. Theoretical comment on Burke. et al. (2010). Behav. Neurosci. 124, 706-709 (2010).
-
(2010)
Behav. Neurosci.
, vol.124
, pp. 706-709
-
-
Baxter, M.G.1
-
69
-
-
77649305060
-
Senescent synapses and hippocampal circuit dynamics
-
This paper provides a comprehensive review of age-related alterations in synaptic physiology in the hippocampus and their potential contribution to cognitive decline
-
Burke, S. N. & Barnes, C. A. Senescent synapses and hippocampal circuit dynamics. Trends Neurosci. 33, 153-161 (2010). This paper provides a comprehensive review of age-related alterations in synaptic physiology in the hippocampus and their potential contribution to cognitive decline.
-
(2010)
Trends Neurosci.
, vol.33
, pp. 153-161
-
-
Burke, S.N.1
Barnes, C.A.2
-
70
-
-
0029821150
-
Preserved neuron number in the hippocampus of aged rats with spatial learning deficits
-
This paper reports rigorous, quantitative evidence that neuron loss does not accompany age-related cognitive decline, reinforcing the search for structural and functional alterations short of neuron death that lead to cognitive decline
-
Rapp, P. R. & Gallagher, M. Preserved neuron number in the hippocampus of aged rats with spatial learning deficits. Proc. Natl Acad. Sci. USA 93, 9926-9930 (1996). This paper reports rigorous, quantitative evidence that neuron loss does not accompany age-related cognitive decline, reinforcing the search for structural and functional alterations short of neuron death that lead to cognitive decline.
-
(1996)
Proc. Natl Acad. Sci. USA
, vol.93
, pp. 9926-9930
-
-
Rapp, P.R.1
Gallagher, M.2
-
71
-
-
0036839248
-
Neuron number in the parahippocampal region is preserved in aged rats with spatial learning deficits
-
Rapp, P. R., Deroche, P. S., Mao, Y. & Burwell, R. D. Neuron number in the parahippocampal region is preserved in aged rats with spatial learning deficits. Cereb. Cortex 12, 1171-1179 (2002).
-
(2002)
Cereb. Cortex
, vol.12
, pp. 1171-1179
-
-
Rapp, P.R.1
Deroche, P.S.2
Mao, Y.3
Burwell, R.D.4
-
72
-
-
0035479759
-
Conservation of neuronal number and size in the entorhinal cortex of behaviorally characterized aged rats
-
Merrill, D. A., Chiba, A. A. & Tuszynski, M. H. Conservation of neuronal number and size in the entorhinal cortex of behaviorally characterized aged rats. J. Comp. Neurol. 438, 445-456 (2001).
-
(2001)
J. Comp. Neurol.
, vol.438
, pp. 445-456
-
-
Merrill, D.A.1
Chiba, A.A.2
Tuszynski, M.H.3
-
73
-
-
33747775155
-
Hippocampal volume is preserved and fails to predict recognition memory impairment in aged rhesus monkeys (Macaca mulatta)
-
Shamy, J. L. et al. Hippocampal volume is preserved and fails to predict recognition memory impairment in aged rhesus monkeys (Macaca mulatta). Neurobiol. Aging 27, 1405-1415 (2006).
-
(2006)
Neurobiol. Aging
, vol.27
, pp. 1405-1415
-
-
Shamy, J.L.1
-
74
-
-
0030713391
-
Preserved number of entorhinal cortex layer II neurons in aged macaque monkeys
-
Gazzaley, A. H., Thakker, M. M., Hof, P. R. &Morrison, J. H. Preserved number of entorhinal cortex layer II neurons in aged macaque monkeys. Neurobiol. Aging 18, 549-553 (1997).
-
(1997)
Neurobiol. Aging
, vol.18
, pp. 549-553
-
-
Gazzaley, A.H.1
Thakker, M.M.2
Hof, P.R.3
Morrison, J.H.4
-
75
-
-
0034601285
-
Conservation of neuron number and size in entorhinal cortex layers, II, III, and V/VI of aged primates
-
Merrill, D. A., Roberts, J. A. & Tuszynski, M. H. Conservation of neuron number and size in entorhinal cortex layers, II, III, and V/VI of aged primates. J. Comp. Neurol. 422, 396-401 (2000).
-
(2000)
J. Comp. Neurol.
, vol.422
, pp. 396-401
-
-
Merrill, D.A.1
Roberts, J.A.2
Tuszynski, M.H.3
-
76
-
-
0031039536
-
Frequency of hippocampal formation atrophy in normal aging and Alzheimer's disease
-
De Leon, M. J. et al. Frequency of hippocampal formation atrophy in normal aging and Alzheimer's disease. Neurobiol. Aging 18, 1-11 (1997).
-
(1997)
Neurobiol. Aging
, vol.18
, pp. 1-11
-
-
De Leon, M.J.1
-
77
-
-
0029979798
-
Profound loss of layer II entorhinal cortex neurons occurs in very mild Alzheimer's disease
-
Gomez-Isla, T. et al. Profound loss of layer II entorhinal cortex neurons occurs in very mild Alzheimer's disease. J. Neurosci. 16, 4491-4500 (1996).
-
(1996)
J. Neurosci.
, vol.16
, pp. 4491-4500
-
-
Gomez-Isla, T.1
-
78
-
-
0345446720
-
Regional brain atrophy rate predicts future cognitive decline: 6-year longitudinal MR imaging study of normal aging
-
Rusinek, H. et al. Regional brain atrophy rate predicts future cognitive decline: 6-year longitudinal MR imaging study of normal aging. Radiology 229, 691-696 (2003).
-
(2003)
Radiology
, vol.229
, pp. 691-696
-
-
Rusinek, H.1
-
79
-
-
44949164660
-
Age-related spatial learning impairment is unrelated to spinophilin immunoreactive spine number and protein levels in rat hippocampus
-
Calhoun, M. E. et al. Age-related spatial learning impairment is unrelated to spinophilin immunoreactive spine number and protein levels in rat hippocampus. Neurobiol. Aging 29, 1256-1264 (2008).
-
(2008)
Neurobiol. Aging
, vol.29
, pp. 1256-1264
-
-
Calhoun, M.E.1
-
80
-
-
1242338796
-
Aging, spatial learning, and total synapse number in the rat CA1 stratum radiatum
-
Geinisman, Y. et al. Aging, spatial learning, and total synapse number in the rat CA1 stratum radiatum. Neurobiol. Aging 25, 407-416 (2004).
-
(2004)
Neurobiol. Aging
, vol.25
, pp. 407-416
-
-
Geinisman, Y.1
-
81
-
-
34247611481
-
Synaptic alterations in CA1 in mild Alzheimer disease and mild cognitive impairment
-
Scheff, S. W., Price, D. A., Schmitt, F. A., DeKosky, S. T. & Mufson, E. J. Synaptic alterations in CA1 in mild Alzheimer disease and mild cognitive impairment. Neurology 68, 1501-1508 (2007).
-
(2007)
Neurology
, vol.68
, pp. 1501-1508
-
-
Scheff, S.W.1
Price, D.A.2
Schmitt, F.A.3
DeKosky, S.T.4
Mufson, E.J.5
-
82
-
-
4444293175
-
Reduction in size of perforated postsynaptic densities in hippocampal axospinous synapses and age-related spatial learning impairments
-
This is one of the more recent papers in an important series of publications highlighting the fact that subtle synaptic alterations revealed by careful quantitative analysis can lead to age-related cognitive decline
-
Nicholson, D. A., Yoshida, R., Berry, R. W., Gallagher, M. & Geinisman, Y. Reduction in size of perforated postsynaptic densities in hippocampal axospinous synapses and age-related spatial learning impairments. J. Neurosci. 24, 7648-7653 (2004). This is one of the more recent papers in an important series of publications highlighting the fact that subtle synaptic alterations revealed by careful quantitative analysis can lead to age-related cognitive decline.
-
(2004)
J. Neurosci.
, vol.24
, pp. 7648-7653
-
-
Nicholson, D.A.1
Yoshida, R.2
Berry, R.W.3
Gallagher, M.4
Geinisman, Y.5
-
83
-
-
0034279244
-
Circuit-specific alterations in hippocampal synaptophysin immunoreactivity predict spatial learning impairment in aged rats
-
Smith, T. D., Adams, M. M., Gallagher, M., Morrison, J. H. & Rapp, P. R. Circuit-specific alterations in hippocampal synaptophysin immunoreactivity predict spatial learning impairment in aged rats. J. Neurosci. 20, 6587-6593 (2000).
-
(2000)
J. Neurosci.
, vol.20
, pp. 6587-6593
-
-
Smith, T.D.1
Adams, M.M.2
Gallagher, M.3
Morrison, J.H.4
Rapp, P.R.5
-
84
-
-
78149285597
-
Age-related synapse loss in hippocampal CA3 is not reversed by caloric restriction
-
Adams, M. M. et al. Age-related synapse loss in hippocampal CA3 is not reversed by caloric restriction. Neuroscience 171, 373-382 (2010).
-
(2010)
Neuroscience
, vol.171
, pp. 373-382
-
-
Adams, M.M.1
-
85
-
-
0026938047
-
Age-related loss of axospinous synapses formed by two afferent systems in the rat dentate gyrus as revealed by the unbiased stereological dissector technique
-
Geinisman, Y., de Toledo-Morrell, L., Morrell, F., Persina, I. S. & Rossi, M. Age-related loss of axospinous synapses formed by two afferent systems in the rat dentate gyrus as revealed by the unbiased stereological dissector technique. Hippocampus 2, 437-444 (1992).
-
(1992)
Hippocampus
, vol.2
, pp. 437-444
-
-
Geinisman, Y.1
De Toledo-Morrell, L.2
Morrell, F.3
Persina, I.S.4
Rossi, M.5
-
86
-
-
0043258253
-
Loss of perforated synapses in the dentate gyrus: Morphological substrate of memory deficit in aged rats
-
Geinisman, Y., de Toledo-Morrell, L. & Morrell, F. Loss of perforated synapses in the dentate gyrus: morphological substrate of memory deficit in aged rats. Proc. Natl Acad. Sci. USA 83, 3027-3031 (1986).
-
(1986)
Proc. Natl Acad. Sci. USA
, vol.83
, pp. 3027-3031
-
-
Geinisman, Y.1
De Toledo-Morrell, L.2
Morrell, F.3
-
87
-
-
0030698871
-
Life and death of neurons in the aging brain
-
Morrison, J. H. & Hof, P. R. Life and death of neurons in the aging brain. Science 278, 412-419 (1997).
-
(1997)
Science
, vol.278
, pp. 412-419
-
-
Morrison, J.H.1
Hof, P.R.2
-
88
-
-
82755162066
-
Synaptic correlates of memory and menopause in the hippocampal dentate gyrus in rhesus monkeys
-
Hara, Y. et al. Synaptic correlates of memory and menopause in the hippocampal dentate gyrus in rhesus monkeys. Neurobiol. Aging 33, 421 (2012).
-
(2012)
Neurobiol. Aging
, vol.33
, pp. 421
-
-
Hara, Y.1
-
89
-
-
79957660661
-
Synaptic characteristics of dentate gyrus axonal boutons and their relationships with aging, menopause, and memory in female rhesus monkeys
-
Using serial-section electron microscopy, this study demonstrated relationships between a reduction in multiple-synapse boutons and age-related cognitive impairment in rhesus monkeys
-
Hara, Y. et al. Synaptic characteristics of dentate gyrus axonal boutons and their relationships with aging, menopause, and memory in female rhesus monkeys. J. Neurosci. 31, 7737-7744 (2011). Using serial-section electron microscopy, this study demonstrated relationships between a reduction in multiple-synapse boutons and age-related cognitive impairment in rhesus monkeys.
-
(2011)
J. Neurosci.
, vol.31
, pp. 7737-7744
-
-
Hara, Y.1
-
90
-
-
59249087963
-
-
Ch. 8 (ed. Riddle, D. R.) CRC Press, North Carolina
-
Shi, L., Adams, M. & Brunso-Bechtold, J. K. in Brain Aging: Models, Methods, and Mechanisms Ch. 8 (ed. Riddle, D. R.) (CRC Press, North Carolina, 2007).
-
(2007)
Brain Aging: Models, Methods, and Mechanisms
-
-
Shi, L.1
Adams, M.2
Brunso-Bechtold, J.K.3
-
91
-
-
79960137052
-
Prominent hippocampal CA3 gene expression profile in neurocognitive aging
-
Haberman, R. P. et al. Prominent hippocampal CA3 gene expression profile in neurocognitive aging. Neurobiol. Aging 32, 1678-1692 (2011).
-
(2011)
Neurobiol. Aging
, vol.32
, pp. 1678-1692
-
-
Haberman, R.P.1
-
92
-
-
22544475288
-
Age-associated alterations of hippocampal place cells are subregion specific
-
Wilson, I. A., Ikonen, S., Gallagher, M., Eichenbaum, H. & Tanila, H. Age-associated alterations of hippocampal place cells are subregion specific. J. Neurosci. 25, 6877-6886 (2005).
-
(2005)
J. Neurosci.
, vol.25
, pp. 6877-6886
-
-
Wilson, I.A.1
Ikonen, S.2
Gallagher, M.3
Eichenbaum, H.4
Tanila, H.5
-
93
-
-
59249087963
-
-
ed. Riddle, D. R. CRC Press, North Carolina
-
Goosens, K. A. & Sapolsky, R. M. in Brain Aging: Models, Methods, and Mechanisms (ed. Riddle, D. R.) (CRC Press, North Carolina, 2007).
-
(2007)
Brain Aging: Models, Methods, and Mechanisms
-
-
Goosens, K.A.1
Sapolsky, R.M.2
-
94
-
-
0036752591
-
Sex, stress and the hippocampus: Allostasis, allostatic load and the aging process
-
McEwen, B. S. Sex, stress and the hippocampus: allostasis, allostatic load and the aging process. Neurobiol. Aging 23, 921-939 (2002).
-
(2002)
Neurobiol. Aging
, vol.23
, pp. 921-939
-
-
McEwen, B.S.1
-
95
-
-
84885801891
-
-
1st edn Ch. 17 (ed. Conrad, C. D.), Wiley-Blackwell, Oxford
-
Bloss, E. B., Morrison, J. H. & McEwen, B. S. in The Handbook of Stress: Neuropsychological Effects on the Brain 1st edn Ch. 17 (ed. Conrad, C. D.), (Wiley-Blackwell, Oxford, 2011).
-
(2011)
The Handbook of Stress: Neuropsychological Effects on the Brain
-
-
Bloss, E.B.1
Morrison, J.H.2
McEwen, B.S.3
-
96
-
-
0037471433
-
Hippocampal cell genesis does not correlate with spatial learning ability in aged rats
-
Merrill, D. A., Karim, R., Darraq, M., Chiba, A. A. &Tuszynski, M. H. Hippocampal cell genesis does not correlate with spatial learning ability in aged rats. J. Comp. Neurol. 459, 201-207 (2003).
-
(2003)
J. Comp. Neurol.
, vol.459
, pp. 201-207
-
-
Merrill, D.A.1
Karim, R.2
Darraq, M.3
Chiba, A.A.4
Tuszynski, M.H.5
-
97
-
-
0042668324
-
Production of new cells in the rat dentate gyrus over the lifespan: Relation to cognitive decline
-
Bizon, J. L. & Gallagher, M. Production of new cells in the rat dentate gyrus over the lifespan: relation to cognitive decline. Eur. J. Neurosci. 18, 215-219 (2003).
-
(2003)
Eur. J. Neurosci.
, vol.18
, pp. 215-219
-
-
Bizon, J.L.1
Gallagher, M.2
-
98
-
-
0344198502
-
Spatial memory performances of aged rats in the water maze predict levels of hippocampal neurogenesis
-
Drapeau, E. et al. Spatial memory performances of aged rats in the water maze predict levels of hippocampal neurogenesis. Proc. Natl Acad. Sci. USA 100, 14385-14390 (2003).
-
(2003)
Proc. Natl Acad. Sci. USA
, vol.100
, pp. 14385-14390
-
-
Drapeau, E.1
-
99
-
-
33644918609
-
More is less: Neurogenesis and age-related cognitive decline in Long-Evans rats
-
Feb doi:10.1126/sageke.2005.7.re2
-
Bizon, J. L. & Gallagher, M. More is less: neurogenesis and age-related cognitive decline in Long-Evans rats. Sci. Aging Knowledge Environ. 16 Feb 2005 (doi:10.1126/sageke.2005.7.re2).
-
(2005)
Sci. Aging Knowledge Environ.
, vol.16
-
-
Bizon, J.L.1
Gallagher, M.2
-
100
-
-
36749037197
-
Diminished adult neurogenesis in the marmoset brain precedes old age
-
Leuner, B., Kozorovitskiy, Y., Gross, C. G. & Gould, E. Diminished adult neurogenesis in the marmoset brain precedes old age. Proc. Natl Acad. Sci. USA 104, 17169-17173 (2007).
-
(2007)
Proc. Natl Acad. Sci. USA
, vol.104
, pp. 17169-17173
-
-
Leuner, B.1
Kozorovitskiy, Y.2
Gross, C.G.3
Gould, E.4
-
101
-
-
73349120950
-
Age-dependent alteration in hippocampal neurogenesis correlates with learning performance of macaque monkeys
-
Aizawa, K., Ageyama, N., Yokoyama, C. & Hisatsune, T. Age-dependent alteration in hippocampal neurogenesis correlates with learning performance of macaque monkeys. Exp. Anim. 58, 403-407 (2009).
-
(2009)
Exp. Anim.
, vol.58
, pp. 403-407
-
-
Aizawa, K.1
Ageyama, N.2
Yokoyama, C.3
Hisatsune, T.4
-
102
-
-
78449295820
-
Primate-specific alterations in neural stem/progenitor cells in the aged hippocampus
-
Aizawa, K., Ageyama, N., Terao, K. & Hisatsune, T. Primate-specific alterations in neural stem/progenitor cells in the aged hippocampus. Neurobiol. Aging 32, 140-150 (2011).
-
(2011)
Neurobiol. Aging
, vol.32
, pp. 140-150
-
-
Aizawa, K.1
Ageyama, N.2
Terao, K.3
Hisatsune, T.4
-
103
-
-
0037936789
-
Impact of aging on hippocampal function: Plasticity, network dynamics, and cognition
-
Rosenzweig, E. S. & Barnes, C. A. Impact of aging on hippocampal function: plasticity, network dynamics, and cognition. Prog. Neurobiol. 69, 143-179 (2003).
-
(2003)
Prog. Neurobiol.
, vol.69
, pp. 143-179
-
-
Rosenzweig, E.S.1
Barnes, C.A.2
-
104
-
-
34249051111
-
Calcium homeostasis and modulation of synaptic plasticity in the aged brain
-
Foster, T. C. Calcium homeostasis and modulation of synaptic plasticity in the aged brain. Aging Cell 6, 319-325 (2007).
-
(2007)
Aging Cell
, vol.6
, pp. 319-325
-
-
Foster, T.C.1
-
105
-
-
77953377074
-
Learning and aging related changes in intrinsic neuronal excitability
-
Oh, M. M., Oliveira, F. A. & Disterhoft, J. F. Learning and aging related changes in intrinsic neuronal excitability. Front. Aging Neurosci. 2, 2 (2010).
-
(2010)
Front. Aging Neurosci.
, vol.2
, pp. 2
-
-
Oh, M.M.1
Oliveira, F.A.2
Disterhoft, J.F.3
-
106
-
-
0025935249
-
Induction of long-term potentiation is associated with an increase in the number of axospinous synapses with segmented postsynaptic densities
-
Geinisman, Y., deToledo-Morrell, L. & Morrell, F. Induction of long-term potentiation is associated with an increase in the number of axospinous synapses with segmented postsynaptic densities. Brain Res. 566, 77-88 (1991).
-
(1991)
Brain Res.
, vol.566
, pp. 77-88
-
-
Geinisman, Y.1
DeToledo-Morrell, L.2
Morrell, F.3
-
107
-
-
0029937619
-
Synapse restructuring associated with the maintenance phase of hippocampal long-term potentiation
-
Geinisman, Y., Detoledo-Morrell, L., Morrell, F., Persina, I. S. & Beatty, M. A. Synapse restructuring associated with the maintenance phase of hippocampal long-term potentiation. J. Comp. Neurol. 368, 413-423 (1996).
-
(1996)
J. Comp. Neurol.
, vol.368
, pp. 413-423
-
-
Geinisman, Y.1
Detoledo-Morrell, L.2
Morrell, F.3
Persina, I.S.4
Beatty, M.A.5
-
108
-
-
0035425931
-
Associative learning elicits the formation of multiple-synapse boutons
-
Geinisman, Y., Berry, R. W., Disterhoft, J. F., Power, J. M. & Van der Zee, E. A. Associative learning elicits the formation of multiple-synapse boutons. J. Neurosci. 21, 5568-5573 (2001).
-
(2001)
J. Neurosci.
, vol.21
, pp. 5568-5573
-
-
Geinisman, Y.1
Berry, R.W.2
Disterhoft, J.F.3
Power, J.M.4
Van Der Zee, E.A.5
-
109
-
-
0035882286
-
Remodeling of synaptic membranes after induction of long-term potentiation
-
Toni, N. et al. Remodeling of synaptic membranes after induction of long-term potentiation. J. Neurosci. 21, 6245-6251 (2001).
-
(2001)
J. Neurosci.
, vol.21
, pp. 6245-6251
-
-
Toni, N.1
-
110
-
-
0029744424
-
Estradiol increases the frequency of multiple synapse boutons in the hippocampal CA1 region of the adult female rat
-
Woolley, C. S., Wenzel, H. J. & Schwartzkroin, P. A. Estradiol increases the frequency of multiple synapse boutons in the hippocampal CA1 region of the adult female rat. J. Comp. Neurol. 373, 108-117 (1996).
-
(1996)
J. Comp. Neurol.
, vol.373
, pp. 108-117
-
-
Woolley, C.S.1
Wenzel, H.J.2
Schwartzkroin, P.A.3
-
111
-
-
0032565962
-
Regulation of actin dynamics through phosphorylation of cofilin by LIM-kinase
-
Arber, S. et al. Regulation of actin dynamics through phosphorylation of cofilin by LIM-kinase. Nature 393, 805-809 (1998).
-
(1998)
Nature
, vol.393
, pp. 805-809
-
-
Arber, S.1
-
112
-
-
0032565769
-
Cofilin phosphorylation by LIM-kinase 1 and its role in Rac-mediated actin reorganization
-
Yang, N. et al. Cofilin phosphorylation by LIM-kinase 1 and its role in Rac-mediated actin reorganization. Nature 393, 809-812 (1998).
-
(1998)
Nature
, vol.393
, pp. 809-812
-
-
Yang, N.1
-
113
-
-
0033529620
-
Signaling from Rho to the actin cytoskeleton through protein kinases ROCK and LIM-kinase
-
Maekawa, M. et al. Signaling from Rho to the actin cytoskeleton through protein kinases ROCK and LIM-kinase. Science 285, 895-898 (1999).
-
(1999)
Science
, vol.285
, pp. 895-898
-
-
Maekawa, M.1
-
114
-
-
0032579934
-
Enhanced expression of AMPA receptor protein at perforated axospinous synapses
-
Desmond, N. L. & Weinberg, R. J. Enhanced expression of AMPA receptor protein at perforated axospinous synapses. Neuroreport 9, 857-860 (1998).
-
(1998)
Neuroreport
, vol.9
, pp. 857-860
-
-
Desmond, N.L.1
Weinberg, R.J.2
-
115
-
-
0037707696
-
Cyclic estrogen replacement improves cognitive function in aged ovariectomized rhesus monkeys
-
This study demonstrated that a cyclic regimen of oestradiol replacement to aged, surgically menopausal monkeys was sufficient to preserve their cognitive abilities relative to monkeys that did not receive hormone treatment
-
Rapp, P. R., Morrison, J. H. & Roberts, J. A. Cyclic estrogen replacement improves cognitive function in aged ovariectomized rhesus monkeys. J. Neurosci. 23, 5708-5714 (2003). This study demonstrated that a cyclic regimen of oestradiol replacement to aged, surgically menopausal monkeys was sufficient to preserve their cognitive abilities relative to monkeys that did not receive hormone treatment.
-
(2003)
J. Neurosci.
, vol.23
, pp. 5708-5714
-
-
Rapp, P.R.1
Morrison, J.H.2
Roberts, J.A.3
-
116
-
-
0038386058
-
Estrogen plus progestin and the incidence of dementia and mild cognitive impairment in postmenopausal women: The Women's Health Initiative Memory Study: A randomized controlled trial
-
Shumaker, S. A. et al. Estrogen plus progestin and the incidence of dementia and mild cognitive impairment in postmenopausal women: the Women's Health Initiative Memory Study: a randomized controlled trial. Jama 289, 2651-2662 (2003).
-
(2003)
Jama
, vol.289
, pp. 2651-2662
-
-
Shumaker, S.A.1
-
117
-
-
33644499808
-
Estrogen-containing hormone therapy and Alzheimer's disease risk: Understanding discrepant inferences from observational and experimental research
-
Henderson, V. W. Estrogen-containing hormone therapy and Alzheimer's disease risk: understanding discrepant inferences from observational and experimental research. Neuroscience 138, 1031-1039 (2006).
-
(2006)
Neuroscience
, vol.138
, pp. 1031-1039
-
-
Henderson, V.W.1
-
118
-
-
33644520914
-
Hormone therapy and cognitive function: Is there a critical period for benefit?
-
Maki, P. M. Hormone therapy and cognitive function: is there a critical period for benefit? Neuroscience 138, 1027-1030 (2006).
-
(2006)
Neuroscience
, vol.138
, pp. 1027-1030
-
-
Maki, P.M.1
-
119
-
-
13544254270
-
Estrogen and memory in women: How can we reconcile the findings?
-
Sherwin, B. B. Estrogen and memory in women: how can we reconcile the findings? Horm. Behav. 47, 371-375 (2005).
-
(2005)
Horm. Behav.
, vol.47
, pp. 371-375
-
-
Sherwin, B.B.1
-
120
-
-
2542540731
-
Hormone therapy: Physiological complexity belies therapeutic simplicity
-
Turgeon, J. L., McDonnell, D. P., Martin, K. A. &Wise, P. M. Hormone therapy: physiological complexity belies therapeutic simplicity. Science 304, 1269-1273 (2004).
-
(2004)
Science
, vol.304
, pp. 1269-1273
-
-
Turgeon, J.L.1
McDonnell, D.P.2
Martin, K.A.3
Wise, P.M.4
-
121
-
-
33749852756
-
Estrogen, menopause, and the aging brain: How basic neuroscience can inform hormone therapy in women
-
Morrison, J. H., Brinton, R. D., Schmidt, P. J. &Gore, A. C. Estrogen, menopause, and the aging brain: how basic neuroscience can inform hormone therapy in women. J. Neurosci. 26, 10332-10348 (2006).
-
(2006)
J. Neurosci.
, vol.26
, pp. 10332-10348
-
-
Morrison, J.H.1
Brinton, R.D.2
Schmidt, P.J.3
Gore, A.C.4
-
122
-
-
0345725010
-
Estrogen and cognition: Applying preclinical findings to clinical perspectives
-
Gibbs, R. B. & Gabor, R. Estrogen and cognition: applying preclinical findings to clinical perspectives. J. Neurosci. Res. 74, 637-643 (2003).
-
(2003)
J. Neurosci. Res.
, vol.74
, pp. 637-643
-
-
Gibbs, R.B.1
Gabor, R.2
-
123
-
-
69549133273
-
Frontiers proposal. National Institute on Aging "bench to bedside: Estrogen as a case study"
-
Asthana, S. et al. Frontiers proposal. National Institute on Aging "bench to bedside: estrogen as a case study". Age 31, 199-210 (2009).
-
(2009)
Age
, vol.31
, pp. 199-210
-
-
Asthana, S.1
-
124
-
-
62949120140
-
Estrogen-induced plasticity from cells to circuits: Predictions for cognitive function
-
Brinton, R. D. Estrogen-induced plasticity from cells to circuits: predictions for cognitive function. Trends Pharmacol. Sci. 30, 212-222 (2009).
-
(2009)
Trends Pharmacol. Sci.
, vol.30
, pp. 212-222
-
-
Brinton, R.D.1
-
125
-
-
84858705877
-
Estrogen and cognitive functioning in women: Lessons we have learned
-
Sherwin, B. B. Estrogen and cognitive functioning in women: lessons we have learned. Behav. Neurosci. 126, 123-127 (2011).
-
(2011)
Behav. Neurosci.
, vol.126
, pp. 123-127
-
-
Sherwin, B.B.1
-
126
-
-
0037032405
-
Hormone therapy and risk of Alzheimer disease: A critical time
-
Resnick, S. M. & Henderson, V. W. Hormone therapy and risk of Alzheimer disease: a critical time. Jama 288, 2170-2172 (2002).
-
(2002)
Jama
, vol.288
, pp. 2170-2172
-
-
Resnick, S.M.1
Henderson, V.W.2
-
127
-
-
33644556837
-
Estrogen and cognitive aging in women
-
Sherwin, B. B. Estrogen and cognitive aging in women. Neuroscience 138, 1021-1026 (2006).
-
(2006)
Neuroscience
, vol.138
, pp. 1021-1026
-
-
Sherwin, B.B.1
-
128
-
-
70350304150
-
Estrogen therapy: Is time of initiation critical for neuroprotection?
-
This article comprehensively reviews studies on oestrogen supplementation in which information about the timing of therapy was provided, allowing an appraisal of evidence for and against the 'critical period' hypothesis
-
Sherwin, B. B. Estrogen therapy: is time of initiation critical for neuroprotection? Nature Rev. Endocrinol. 5, 620-627 (2009). This article comprehensively reviews studies on oestrogen supplementation in which information about the timing of therapy was provided, allowing an appraisal of evidence for and against the 'critical period' hypothesis.
-
(2009)
Nature Rev. Endocrinol.
, vol.5
, pp. 620-627
-
-
Sherwin, B.B.1
-
129
-
-
0037032401
-
Hormone replacement therapy and incidence of Alzheimer disease in older women: The Cache County Study
-
Zandi, P. P. et al. Hormone replacement therapy and incidence of Alzheimer disease in older women: the Cache County Study. Jama 288, 2123-2129 (2002).
-
(2002)
Jama
, vol.288
, pp. 2123-2129
-
-
Zandi, P.P.1
-
130
-
-
79952311053
-
Oophorectomy, menopause, estrogen treatment, and cognitive aging: Clinical evidence for a window of opportunity
-
Rocca, W. A., Grossardt, B. R. & Shuster, L. T. Oophorectomy, menopause, estrogen treatment, and cognitive aging: clinical evidence for a window of opportunity. Brain Res. 1379, 188-198 (2011).
-
(2011)
Brain Res.
, vol.1379
, pp. 188-198
-
-
Rocca, W.A.1
Grossardt, B.R.2
Shuster, L.T.3
-
131
-
-
0034946795
-
Different modes of hippocampal plasticity in response to estrogen in young and aged female rats
-
Adams, M. M., Shah, R. A., Janssen, W. G. &Morrison, J. H. Different modes of hippocampal plasticity in response to estrogen in young and aged female rats. Proc. Natl Acad. Sci. USA 98, 8071-8076 (2001).
-
(2001)
Proc. Natl Acad. Sci. USA
, vol.98
, pp. 8071-8076
-
-
Adams, M.M.1
Shah, R.A.2
Janssen, W.G.3
Morrison, J.H.4
-
132
-
-
0038520900
-
The cognitive effects of ovariectomy and estrogen replacement are modulated by aging
-
Savonenko, A. V. & Markowska, A. L. The cognitive effects of ovariectomy and estrogen replacement are modulated by aging. Neuroscience 119, 821-830 (2003).
-
(2003)
Neuroscience
, vol.119
, pp. 821-830
-
-
Savonenko, A.V.1
Markowska, A.L.2
-
133
-
-
0036581329
-
Estrogen and aging affect the subcellular distribution of estrogen receptor-α in the hippocampus of female rats
-
Adams, M. M. et al. Estrogen and aging affect the subcellular distribution of estrogen receptor-α in the hippocampus of female rats. J. Neurosci. 22, 3608-3614 (2002).
-
(2002)
J. Neurosci.
, vol.22
, pp. 3608-3614
-
-
Adams, M.M.1
-
134
-
-
7044267351
-
Rapid and persistent modulation of actin dynamics regulates postsynaptic reorganization underlying bidirectional plasticity
-
Okamoto, K., Nagai, T., Miyawaki, A. & Hayashi, Y. Rapid and persistent modulation of actin dynamics regulates postsynaptic reorganization underlying bidirectional plasticity. Nature Neurosci. 7, 1104-1112 (2004).
-
(2004)
Nature Neurosci.
, vol.7
, pp. 1104-1112
-
-
Okamoto, K.1
Nagai, T.2
Miyawaki, A.3
Hayashi, Y.4
-
135
-
-
50249182795
-
Estrous cycle regulates activation of hippocampal Akt, LIM kinase, and neurotrophin receptors in C57BL/6 mice
-
Spencer, J. L., Waters, E. M., Milner, T. A. &McEwen, B. S. Estrous cycle regulates activation of hippocampal Akt, LIM kinase, and neurotrophin receptors in C57BL/6 mice. Neuroscience 155, 1106-1119 (2008).
-
(2008)
Neuroscience
, vol.155
, pp. 1106-1119
-
-
Spencer, J.L.1
Waters, E.M.2
Milner, T.A.3
McEwen, B.S.4
-
136
-
-
40949153802
-
Estrogen and aging affect synaptic distribution of phosphorylated LIM kinase (pLIMK) in CA1 region of female rat hippocampus
-
Yildirim, M. et al. Estrogen and aging affect synaptic distribution of phosphorylated LIM kinase (pLIMK) in CA1 region of female rat hippocampus. Neuroscience 152, 360-370 (2008).
-
(2008)
Neuroscience
, vol.152
, pp. 360-370
-
-
Yildirim, M.1
-
137
-
-
33845287622
-
Dietary phytoestrogens enhance spatial memory and spine density in the hippocampus and prefrontal cortex of ovariectomized rats
-
Luine, V., Attalla, S., Mohan, G., Costa, A. &Frankfurt, M. Dietary phytoestrogens enhance spatial memory and spine density in the hippocampus and prefrontal cortex of ovariectomized rats. Brain Res. 1126, 183-187 (2006).
-
(2006)
Brain Res.
, vol.1126
, pp. 183-187
-
-
Luine, V.1
Attalla, S.2
Mohan, G.3
Costa, A.4
Frankfurt, M.5
-
138
-
-
77957840834
-
Estrogen promotes stress sensitivity in a prefrontal cortex-amygdala pathway
-
Shansky, R. M. et al. Estrogen promotes stress sensitivity in a prefrontal cortex-amygdala pathway. Cereb. Cortex 20, 2560-2567 (2010).
-
(2010)
Cereb. Cortex
, vol.20
, pp. 2560-2567
-
-
Shansky, R.M.1
-
139
-
-
0037619881
-
Estrogen increases the number of spinophilin-immunoreactive spines in the hippocampus of young and aged female rhesus monkeys
-
Hao, J. et al. Estrogen increases the number of spinophilin- immunoreactive spines in the hippocampus of young and aged female rhesus monkeys. J. Comp. Neurol. 465, 540-550 (2003).
-
(2003)
J. Comp. Neurol.
, vol.465
, pp. 540-550
-
-
Hao, J.1
-
140
-
-
0037140793
-
Gonadal hormones are responsible for maintaining the integrity of spine synapses in the CA1 hippocampal subfield of female nonhuman primates
-
Leranth, C., Shanabrough, M. & Redmond, D. E. Gonadal hormones are responsible for maintaining the integrity of spine synapses in the CA1 hippocampal subfield of female nonhuman primates. J. Comp. Neurol. 447, 34-42 (2002).
-
(2002)
J. Comp. Neurol.
, vol.447
, pp. 34-42
-
-
Leranth, C.1
Shanabrough, M.2
Redmond, D.E.3
-
141
-
-
0034990661
-
Prefrontal cortex as the site of estrogen's effect on cognition
-
Keenan, P. A., Ezzat, W. H., Ginsburg, K. & Moore, G. J. Prefrontal cortex as the site of estrogen's effect on cognition. Psychoneuroendocrinology 26, 577-590 (2001).
-
(2001)
Psychoneuroendocrinology
, vol.26
, pp. 577-590
-
-
Keenan, P.A.1
Ezzat, W.H.2
Ginsburg, K.3
Moore, G.J.4
-
142
-
-
33747760358
-
Hippocampal synaptic loss in early Alzheimer's disease and mild cognitive impairment
-
This paper reports quantitative electron microscopy data from human brain showing that there is extensive synapse loss early in the progression of Alzheimer's disease
-
Scheff, S. W., Price, D. A., Schmitt, F. A. & Mufson, E. J. Hippocampal synaptic loss in early Alzheimer's disease and mild cognitive impairment. Neurobiol. Aging 27, 1372-1384 (2006). This paper reports quantitative electron microscopy data from human brain showing that there is extensive synapse loss early in the progression of Alzheimer's disease.
-
(2006)
Neurobiol. Aging
, vol.27
, pp. 1372-1384
-
-
Scheff, S.W.1
Price, D.A.2
Schmitt, F.A.3
Mufson, E.J.4
-
143
-
-
47049111840
-
Stereologic estimates of total spinophilin-immunoreactive spine number in area 9 and the CA1 field: Relationship with the progression of Alzheimer's disease
-
Akram, A. et al. Stereologic estimates of total spinophilin- immunoreactive spine number in area 9 and the CA1 field: relationship with the progression of Alzheimer's disease. Neurobiol. Aging 29, 1296-1307 (2008).
-
(2008)
Neurobiol. Aging
, vol.29
, pp. 1296-1307
-
-
Akram, A.1
-
144
-
-
79955654901
-
The influence of synaptic activity on neuronal health
-
This review highlights the relationship between synaptic events and alterations and the risk of neuron death, a relationship that is likely to be crucially important in the transition from synaptic alterations to Alzheimer's disease in humans
-
Bell, K. F. & Hardingham, G. E. The influence of synaptic activity on neuronal health. Curr. Opin. Neurobiol. 21, 299-305 (2011). This review highlights the relationship between synaptic events and alterations and the risk of neuron death, a relationship that is likely to be crucially important in the transition from synaptic alterations to Alzheimer's disease in humans.
-
(2011)
Curr. Opin. Neurobiol.
, vol.21
, pp. 299-305
-
-
Bell, K.F.1
Hardingham, G.E.2
-
145
-
-
33645520634
-
Early-onset behavioral and synaptic deficits in a mouse model of Alzheimer's disease
-
Jacobsen, J. S. et al. Early-onset behavioral and synaptic deficits in a mouse model of Alzheimer's disease. Proc. Natl Acad. Sci. USA 103, 5161-5166 (2006).
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, pp. 5161-5166
-
-
Jacobsen, J.S.1
-
146
-
-
23044445669
-
Regulation of NMDA receptor trafficking by amyloid-β
-
Snyder, E. M. et al. Regulation of NMDA receptor trafficking by amyloid-β. Nature Neurosci. 8, 1051-1058 (2005).
-
(2005)
Nature Neurosci.
, vol.8
, pp. 1051-1058
-
-
Snyder, E.M.1
-
147
-
-
0037174618
-
Alzheimer's disease is a synaptic failure
-
Selkoe, D. J. Alzheimer's disease is a synaptic failure. Science 298, 789-791 (2002).
-
(2002)
Science
, vol.298
, pp. 789-791
-
-
Selkoe, D.J.1
-
148
-
-
44549087765
-
Soluble oligomers of the amyloid β-protein impair synaptic plasticity and behavior
-
Selkoe, D. J. Soluble oligomers of the amyloid β-protein impair synaptic plasticity and behavior. Behav. Brain Res. 192, 106-113 (2008).
-
(2008)
Behav. Brain Res.
, vol.192
, pp. 106-113
-
-
Selkoe, D.J.1
-
149
-
-
80052962821
-
A pathophysiological framework of hippocampal dysfunction in ageing and disease
-
Small, S. A., Schobel, S. A., Buxton, R. B., Witter, M. P. & Barnes, C. A. A pathophysiological framework of hippocampal dysfunction in ageing and disease. Nature Rev. Neurosci. 12, 585-601 (2011).
-
(2011)
Nature Rev. Neurosci.
, vol.12
, pp. 585-601
-
-
Small, S.A.1
Schobel, S.A.2
Buxton, R.B.3
Witter, M.P.4
Barnes, C.A.5
-
150
-
-
77957191406
-
Synaptic estrogen receptor-α levels in prefrontal cortex in female rhesus monkeys and their correlation with cognitive performance
-
Wang, A. C., Hara, Y., Janssen, W. G., Rapp, P. R. &Morrison, J. H. Synaptic estrogen receptor-α levels in prefrontal cortex in female rhesus monkeys and their correlation with cognitive performance. J. Neurosci. 30, 12770-12776 (2010).
-
(2010)
J. Neurosci.
, vol.30
, pp. 12770-12776
-
-
Wang, A.C.1
Hara, Y.2
Janssen, W.G.3
Rapp, P.R.4
Morrison, J.H.5
-
151
-
-
9144237423
-
Adult male rat hippocampus synthesizes estradiol from pregnenolone by cytochromes P45017α and P450 aromatase localized in neurons
-
Hojo, Y. et al. Adult male rat hippocampus synthesizes estradiol from pregnenolone by cytochromes P45017α and P450 aromatase localized in neurons. Proc. Natl Acad. Sci. USA 101, 865-870 (2004).
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, pp. 865-870
-
-
Hojo, Y.1
-
152
-
-
28844450653
-
Neurosteroid synthesis in the hippocampus: Role in synaptic plasticity
-
Rune, G. M. & Frotscher, M. Neurosteroid synthesis in the hippocampus: role in synaptic plasticity. Neuroscience 136, 833-842 (2005).
-
(2005)
Neuroscience
, vol.136
, pp. 833-842
-
-
Rune, G.M.1
Frotscher, M.2
-
153
-
-
80053223778
-
Adrenal androgens and the menopausal transition
-
Lasley, B. L., Crawford, S. & McConnell, D. S. Adrenal androgens and the menopausal transition. Obstet. Gynecol. Clin. North Am. 38, 467-475 (2011).
-
(2011)
Obstet. Gynecol. Clin. North Am.
, vol.38
, pp. 467-475
-
-
Lasley, B.L.1
Crawford, S.2
McConnell, D.S.3
-
155
-
-
79958056062
-
Mindspan: Lessons from rat models of neurocognitive aging
-
Gallagher, M., Stocker, A. M. & Koh, M. T. Mindspan: lessons from rat models of neurocognitive aging. ILAR J. 52, 32-40 (2011).
-
(2011)
ILAR J.
, vol.52
, pp. 32-40
-
-
Gallagher, M.1
Stocker, A.M.2
Koh, M.T.3
|