메뉴 건너뛰기




Volumn 171, Issue 2, 2010, Pages 373-382

Age-related synapse loss in hippocampal CA3 is not reversed by caloric restriction

Author keywords

Dietary restriction; Electron microscopy; Hippocampus; Rat; Serial reconstruction; Synapses

Indexed keywords

PROTEIN; SYNAPTIC PROTEIN; UNCLASSIFIED DRUG;

EID: 78149285597     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2010.09.022     Document Type: Article
Times cited : (24)

References (50)
  • 2
    • 0026549426 scopus 로고
    • Alteration in the pattern of nerve terminal protein immunoreactivity in the perforant pathway in Alzheimer's disease and in rats after entorhinal lesions
    • Cabalka L.M., Hyman B.T., Goodlett C.R., Ritchie T.C., Van Hoesen G.W. Alteration in the pattern of nerve terminal protein immunoreactivity in the perforant pathway in Alzheimer's disease and in rats after entorhinal lesions. Neurobiol Aging 1992, 13:283-291.
    • (1992) Neurobiol Aging , vol.13 , pp. 283-291
    • Cabalka, L.M.1    Hyman, B.T.2    Goodlett, C.R.3    Ritchie, T.C.4    Van Hoesen, G.W.5
  • 3
    • 0006975664 scopus 로고
    • Numerical changes in rat hippocampal synapses. An effect of "aging"?
    • De Groot D.M.G., Bierman E.P.B. Numerical changes in rat hippocampal synapses. An effect of "aging"?. Acta Stereol 1987, 6:53-58.
    • (1987) Acta Stereol , vol.6 , pp. 53-58
    • De Groot, D.M.G.1    Bierman, E.P.B.2
  • 4
    • 41349086636 scopus 로고    scopus 로고
    • Spine dynamics and synapse remodeling during LTP and memory processes
    • De R.M., Klauser P., Garcia P.M., Poglia L., Muller D. Spine dynamics and synapse remodeling during LTP and memory processes. Prog Brain Res 2008, 169:199-207.
    • (2008) Prog Brain Res , vol.169 , pp. 199-207
    • De, R.M.1    Klauser, P.2    Garcia, P.M.3    Poglia, L.4    Muller, D.5
  • 5
    • 0023000726 scopus 로고
    • Changes in the postsynaptic density with long-term potentiation in the dentate gyrus
    • Desmond N.L., Levy W.B. Changes in the postsynaptic density with long-term potentiation in the dentate gyrus. J Comp Neurol 1986, 253:476-482.
    • (1986) J Comp Neurol , vol.253 , pp. 476-482
    • Desmond, N.L.1    Levy, W.B.2
  • 7
    • 0034738147 scopus 로고    scopus 로고
    • Caloric restriction prevents age-related deficits in LTP and in NMDA receptor expression
    • Eckles-Smith K., Clayton D., Bickford P., Browning M.D. Caloric restriction prevents age-related deficits in LTP and in NMDA receptor expression. Brain Res Mol Brain Res 2000, 78:154-162.
    • (2000) Brain Res Mol Brain Res , vol.78 , pp. 154-162
    • Eckles-Smith, K.1    Clayton, D.2    Bickford, P.3    Browning, M.D.4
  • 8
    • 33947596408 scopus 로고    scopus 로고
    • Susceptibility to induction of long-term depression is associated with impaired memory in aged Fischer 344 rats
    • Foster T.C., Kumar A. Susceptibility to induction of long-term depression is associated with impaired memory in aged Fischer 344 rats. Neurobiol Learn Mem 2007, 87:522-535.
    • (2007) Neurobiol Learn Mem , vol.87 , pp. 522-535
    • Foster, T.C.1    Kumar, A.2
  • 9
    • 0346780703 scopus 로고    scopus 로고
    • Differences in the expression of AMPA and NMDA receptors between axospinous perforated and nonperforated synapses are related to the configuration and size of postsynaptic densities
    • Ganeshina O., Berry R.W., Petralia R.S., Nicholson D.A., Geinisman Y. Differences in the expression of AMPA and NMDA receptors between axospinous perforated and nonperforated synapses are related to the configuration and size of postsynaptic densities. J Comp Neurol 2004, 468:86-95.
    • (2004) J Comp Neurol , vol.468 , pp. 86-95
    • Ganeshina, O.1    Berry, R.W.2    Petralia, R.S.3    Nicholson, D.A.4    Geinisman, Y.5
  • 10
    • 1942424881 scopus 로고    scopus 로고
    • Synapses with a segmented, completely partitioned postsynaptic density express more AMPA receptors than other axospinous synaptic junctions
    • Ganeshina O., Berry R.W., Petralia R.S., Nicholson D.A., Geinisman Y. Synapses with a segmented, completely partitioned postsynaptic density express more AMPA receptors than other axospinous synaptic junctions. Neuroscience 2004, 125:615-623.
    • (2004) Neuroscience , vol.125 , pp. 615-623
    • Ganeshina, O.1    Berry, R.W.2    Petralia, R.S.3    Nicholson, D.A.4    Geinisman, Y.5
  • 11
    • 0025935249 scopus 로고
    • Induction of long-term potentiation is associated with an increase in the number of axospinous synapses with segmented postsynaptic densities
    • Geinisman Y., Detoledo-Morrell L., Morrell F. Induction of long-term potentiation is associated with an increase in the number of axospinous synapses with segmented postsynaptic densities. Brain Res 1991, 566:77-88.
    • (1991) Brain Res , vol.566 , pp. 77-88
    • Geinisman, Y.1    Detoledo-Morrell, L.2    Morrell, F.3
  • 12
    • 0029937619 scopus 로고    scopus 로고
    • Synapse restructuring associated with the maintenance phase of hippocampal long-term potentiation
    • Geinisman Y., Detoledo-Morrell L., Morrell F., Persina I.S., Beatty M.A. Synapse restructuring associated with the maintenance phase of hippocampal long-term potentiation. J Comp Neurol 1996, 368:413-423.
    • (1996) J Comp Neurol , vol.368 , pp. 413-423
    • Geinisman, Y.1    Detoledo-Morrell, L.2    Morrell, F.3    Persina, I.S.4    Beatty, M.A.5
  • 14
    • 0027486079 scopus 로고
    • Structural synaptic correlate of long-term potentiation: formation of axospinous synapses with multiple, completely partitioned transmission zones
    • Geinisman Y., Toledo-Morrell L., Morrell F., Heller R.E., Rossi M., Parshall R.F. Structural synaptic correlate of long-term potentiation: formation of axospinous synapses with multiple, completely partitioned transmission zones. Hippocampus 1993, 3:435-445.
    • (1993) Hippocampus , vol.3 , pp. 435-445
    • Geinisman, Y.1    Toledo-Morrell, L.2    Morrell, F.3    Heller, R.E.4    Rossi, M.5    Parshall, R.F.6
  • 15
    • 0026938047 scopus 로고
    • Age-related loss of axospinous synapses formed by two afferent systems in the rat dentate gyrus as revealed by the unbiased stereological dissector technique
    • Geinisman Y., Toledo-Morrell L., Morrell F., Persina I.S., Rossi M. Age-related loss of axospinous synapses formed by two afferent systems in the rat dentate gyrus as revealed by the unbiased stereological dissector technique. Hippocampus 1992, 2:437-444.
    • (1992) Hippocampus , vol.2 , pp. 437-444
    • Geinisman, Y.1    Toledo-Morrell, L.2    Morrell, F.3    Persina, I.S.4    Rossi, M.5
  • 16
    • 0025275803 scopus 로고
    • Synaptophysin expression in the striatum in Huntington's disease
    • Goto S., Hirano A. Synaptophysin expression in the striatum in Huntington's disease. Acta Neuropathol 1990, 80:88-91.
    • (1990) Acta Neuropathol , vol.80 , pp. 88-91
    • Goto, S.1    Hirano, A.2
  • 17
    • 0028801680 scopus 로고
    • Loss of synaptophysin-like immunoreactivity in the hippocampal formation is an early phenomenon in Alzheimer's disease
    • Heinonen O., Soininen H., Sorvari H., Kosunen O., Paljarvi L., Koivisto E., Riekkinen P.J. Loss of synaptophysin-like immunoreactivity in the hippocampal formation is an early phenomenon in Alzheimer's disease. Neuroscience 1995, 64:375-384.
    • (1995) Neuroscience , vol.64 , pp. 375-384
    • Heinonen, O.1    Soininen, H.2    Sorvari, H.3    Kosunen, O.4    Paljarvi, L.5    Koivisto, E.6    Riekkinen, P.J.7
  • 19
    • 49449107562 scopus 로고    scopus 로고
    • Dendritic spine plasticity-current understanding from in vivo] studies
    • Knott G., Holtmaat A. Dendritic spine plasticity-current understanding from in vivo] studies. Brain Res Rev 2008, 58:282-289.
    • (2008) Brain Res Rev , vol.58 , pp. 282-289
    • Knott, G.1    Holtmaat, A.2
  • 20
    • 11144265809 scopus 로고    scopus 로고
    • Intracellular calcium stores contribute to increased susceptibility to LTD induction during aging
    • Kumar A., Foster T.C. Intracellular calcium stores contribute to increased susceptibility to LTD induction during aging. Brain Res 2005, 1031:125-128.
    • (2005) Brain Res , vol.1031 , pp. 125-128
    • Kumar, A.1    Foster, T.C.2
  • 21
    • 3142700003 scopus 로고    scopus 로고
    • New spines, new memories
    • Leuner B., Shors T.J. New spines, new memories. Mol Neurobiol 2004, 29:117-130.
    • (2004) Mol Neurobiol , vol.29 , pp. 117-130
    • Leuner, B.1    Shors, T.J.2
  • 22
    • 0036145443 scopus 로고    scopus 로고
    • Retardation of cognitive aging by life-long diet restriction: implications for genetic variance
    • Markowska A.L., Savonenko A. Retardation of cognitive aging by life-long diet restriction: implications for genetic variance. Neurobiol Aging 2002, 23:75-86.
    • (2002) Neurobiol Aging , vol.23 , pp. 75-86
    • Markowska, A.L.1    Savonenko, A.2
  • 25
  • 26
    • 0028235419 scopus 로고
    • Synaptic and neuritic alterations during the progression of Alzheimer's disease
    • Masliah E., Mallory M., Hansen L., DeTeresa R., Alford M., Terry R. Synaptic and neuritic alterations during the progression of Alzheimer's disease. Neurosci Lett 1994, 174:67-72.
    • (1994) Neurosci Lett , vol.174 , pp. 67-72
    • Masliah, E.1    Mallory, M.2    Hansen, L.3    DeTeresa, R.4    Alford, M.5    Terry, R.6
  • 27
    • 0027390458 scopus 로고
    • Quantitative synaptic alterations in the human neocortex during normal aging
    • Masliah E., Mallory M., Hansen L., DeTeresa R., Terry R.D. Quantitative synaptic alterations in the human neocortex during normal aging. Neurology 1993, 43:192-197.
    • (1993) Neurology , vol.43 , pp. 192-197
    • Masliah, E.1    Mallory, M.2    Hansen, L.3    DeTeresa, R.4    Terry, R.D.5
  • 28
    • 0032500822 scopus 로고    scopus 로고
    • Effectiveness of caloric restriction in preventing age-related changes in rat skeletal muscle
    • Mayhew M., Renganathan M., Delbono O. Effectiveness of caloric restriction in preventing age-related changes in rat skeletal muscle. Biochem Biophys Res Commun 1998, 251:95-99.
    • (1998) Biochem Biophys Res Commun , vol.251 , pp. 95-99
    • Mayhew, M.1    Renganathan, M.2    Delbono, O.3
  • 29
    • 2342626539 scopus 로고    scopus 로고
    • Long-term synaptic morphometry changes after induction of long-term potentiation and long-term depression in the dentate gyrus of awake rats are not simply mirror phenomena
    • Mezey S., Doyere V., De Souza I., Harrison E., Cambon K., Kendal C.E., Davies H., Laroche S., Stewart M.G. Long-term synaptic morphometry changes after induction of long-term potentiation and long-term depression in the dentate gyrus of awake rats are not simply mirror phenomena. Eur J Neurosci 2004, 19:2310-2318.
    • (2004) Eur J Neurosci , vol.19 , pp. 2310-2318
    • Mezey, S.1    Doyere, V.2    De Souza, I.3    Harrison, E.4    Cambon, K.5    Kendal, C.E.6    Davies, H.7    Laroche, S.8    Stewart, M.G.9
  • 32
    • 59149102797 scopus 로고    scopus 로고
    • Axospinous synaptic subtype-specific differences in structure, size, ionotropic receptor expression, and connectivity in apical dendritic regions of rat hippocampal CA1 pyramidal neurons
    • Nicholson D.A., Geinisman Y. Axospinous synaptic subtype-specific differences in structure, size, ionotropic receptor expression, and connectivity in apical dendritic regions of rat hippocampal CA1 pyramidal neurons. J Comp Neurol 2009, 512:399-418.
    • (2009) J Comp Neurol , vol.512 , pp. 399-418
    • Nicholson, D.A.1    Geinisman, Y.2
  • 33
    • 33646137361 scopus 로고    scopus 로고
    • Distance-dependent differences in synapse number and AMPA receptor expression in hippocampal CA1 pyramidal neurons
    • Nicholson D.A., Trana R., Katz Y., Kath W.L., Spruston N., Geinisman Y. Distance-dependent differences in synapse number and AMPA receptor expression in hippocampal CA1 pyramidal neurons. Neuron 2006, 50:431-442.
    • (2006) Neuron , vol.50 , pp. 431-442
    • Nicholson, D.A.1    Trana, R.2    Katz, Y.3    Kath, W.L.4    Spruston, N.5    Geinisman, Y.6
  • 34
    • 4444293175 scopus 로고    scopus 로고
    • Reduction in size of perforated postsynaptic densities in hippocampal axospinous synapses and age-related spatial learning impairments
    • Nicholson D.A., Yoshida R., Berry R.W., Gallagher M., Geinisman Y. Reduction in size of perforated postsynaptic densities in hippocampal axospinous synapses and age-related spatial learning impairments. J Neurosci 2004, 24:7648-7653.
    • (2004) J Neurosci , vol.24 , pp. 7648-7653
    • Nicholson, D.A.1    Yoshida, R.2    Berry, R.W.3    Gallagher, M.4    Geinisman, Y.5
  • 35
    • 0029795945 scopus 로고    scopus 로고
    • Increased susceptibility to induction of long-term depression and long-term potentiation reversal during aging
    • Norris C.M., Korol D.L., Foster T.C. Increased susceptibility to induction of long-term depression and long-term potentiation reversal during aging. J Neurosci 1996, 16:5382-5392.
    • (1996) J Neurosci , vol.16 , pp. 5382-5392
    • Norris, C.M.1    Korol, D.L.2    Foster, T.C.3
  • 37
    • 0035900632 scopus 로고    scopus 로고
    • Effects of age and insulin-like growth factor-1 on neuron and synapse numbers in area CA3 of hippocampus
    • Poe B.H., Linville C., Riddle D.R., Sonntag W.E., Brunso-Bechtold J.K. Effects of age and insulin-like growth factor-1 on neuron and synapse numbers in area CA3 of hippocampus. Neuroscience 2001, 107:231-238.
    • (2001) Neuroscience , vol.107 , pp. 231-238
    • Poe, B.H.1    Linville, C.2    Riddle, D.R.3    Sonntag, W.E.4    Brunso-Bechtold, J.K.5
  • 38
    • 5444251163 scopus 로고    scopus 로고
    • Growth hormone treatment attenuates age-related changes in hippocampal short-term plasticity and spatial learning
    • Ramsey M.M., Weiner J.L., Moore T.P., Carter C.S., Sonntag W.E. Growth hormone treatment attenuates age-related changes in hippocampal short-term plasticity and spatial learning. Neuroscience 2004, 129:119-127.
    • (2004) Neuroscience , vol.129 , pp. 119-127
    • Ramsey, M.M.1    Weiner, J.L.2    Moore, T.P.3    Carter, C.S.4    Sonntag, W.E.5
  • 39
    • 45749083019 scopus 로고    scopus 로고
    • Molecular mechanisms of dendritic spine development and maintenance
    • Sala C., Cambianica I., Rossi F. Molecular mechanisms of dendritic spine development and maintenance. Acta Neurobiol Exp Wars 2008, 68:289-304.
    • (2008) Acta Neurobiol Exp Wars , vol.68 , pp. 289-304
    • Sala, C.1    Cambianica, I.2    Rossi, F.3
  • 40
    • 34250622873 scopus 로고    scopus 로고
    • Caloric restriction eliminates the aging-related decline in NMDA and AMPA receptor subunits in the rat hippocampus and induces homeostasis
    • Shi L., Adams M.M., Linville M.C., Newton I.G., Forbes M.E., Long A.B., Riddle D.R., Brunso-Bechtold J.K. Caloric restriction eliminates the aging-related decline in NMDA and AMPA receptor subunits in the rat hippocampus and induces homeostasis. Exp Neurol 2007, 206:70-79.
    • (2007) Exp Neurol , vol.206 , pp. 70-79
    • Shi, L.1    Adams, M.M.2    Linville, M.C.3    Newton, I.G.4    Forbes, M.E.5    Long, A.B.6    Riddle, D.R.7    Brunso-Bechtold, J.K.8
  • 41
    • 0037155490 scopus 로고    scopus 로고
    • Caloric restricted male rats demonstrate fewer synapses in layer 2 of sensorimotor cortex
    • Shi L., Poe B.H., Constance L.M., Sonntag W.E., Brunso-Bechtold J.K. Caloric restricted male rats demonstrate fewer synapses in layer 2 of sensorimotor cortex. Brain Res 2002, 931:32-40.
    • (2002) Brain Res , vol.931 , pp. 32-40
    • Shi, L.1    Poe, B.H.2    Constance, L.M.3    Sonntag, W.E.4    Brunso-Bechtold, J.K.5
  • 42
    • 0034279244 scopus 로고    scopus 로고
    • Circuit-specific alterations in hippocampal synaptophysin immunoreactivity predict spatial learning impairment in aged rats
    • Smith T.D., Adams M.M., Gallagher M., Morrison J.H., Rapp P.R. Circuit-specific alterations in hippocampal synaptophysin immunoreactivity predict spatial learning impairment in aged rats. J Neurosci 2000, 20:6587-6593.
    • (2000) J Neurosci , vol.20 , pp. 6587-6593
    • Smith, T.D.1    Adams, M.M.2    Gallagher, M.3    Morrison, J.H.4    Rapp, P.R.5
  • 43
    • 21844455004 scopus 로고    scopus 로고
    • Chemically induced long-term potentiation increases the number of perforated and complex postsynaptic densities but does not alter dendritic spine volume in CA1 of adult mouse hippocampal slices
    • Stewart M.G., Medvedev N.I., Popov V.I., Schoepfer R., Davies H.A., Murphy K., Dallerac G.M., Kraev I.V., Rodriguez J.J. Chemically induced long-term potentiation increases the number of perforated and complex postsynaptic densities but does not alter dendritic spine volume in CA1 of adult mouse hippocampal slices. Eur J Neurosci 2005, 21:3368-3378.
    • (2005) Eur J Neurosci , vol.21 , pp. 3368-3378
    • Stewart, M.G.1    Medvedev, N.I.2    Popov, V.I.3    Schoepfer, R.4    Davies, H.A.5    Murphy, K.6    Dallerac, G.M.7    Kraev, I.V.8    Rodriguez, J.J.9
  • 44
    • 0342375000 scopus 로고    scopus 로고
    • Different modes of expression of AMPA and NMDA receptors in hippocampal synapses
    • Takumi Y., Ramirez-Leon V., Laake P., Rinvik E., Ottersen O.P. Different modes of expression of AMPA and NMDA receptors in hippocampal synapses. Nat Neurosci 1999, 2:618-624.
    • (1999) Nat Neurosci , vol.2 , pp. 618-624
    • Takumi, Y.1    Ramirez-Leon, V.2    Laake, P.3    Rinvik, E.4    Ottersen, O.P.5
  • 46
    • 0032919522 scopus 로고    scopus 로고
    • Sequential changes in the synaptic structural profile following long-term potentiation in the rat dentate gyrus. I. The intermediate maintenance phase
    • Weeks A.C., Ivanco T.L., Leboutillier J.C., Racine R.J., Petit T.L. Sequential changes in the synaptic structural profile following long-term potentiation in the rat dentate gyrus. I. The intermediate maintenance phase. Synapse 1999, 31:97-107.
    • (1999) Synapse , vol.31 , pp. 97-107
    • Weeks, A.C.1    Ivanco, T.L.2    Leboutillier, J.C.3    Racine, R.J.4    Petit, T.L.5
  • 47
    • 0035112720 scopus 로고    scopus 로고
    • Sequential changes in the synaptic structural profile following long-term potentiation in the rat dentate gyrus. III. Long-term maintenance phase
    • Weeks A.C., Ivanco T.L., Leboutillier J.C., Racine R.J., Petit T.L. Sequential changes in the synaptic structural profile following long-term potentiation in the rat dentate gyrus. III. Long-term maintenance phase. Synapse 2001, 40:74-84.
    • (2001) Synapse , vol.40 , pp. 74-84
    • Weeks, A.C.1    Ivanco, T.L.2    Leboutillier, J.C.3    Racine, R.J.4    Petit, T.L.5
  • 48
    • 0032903935 scopus 로고    scopus 로고
    • Effect of calorie restriction on in vivo] glucose metabolism by individual tissues in rats
    • Wetter T.J., Gazdag A.C., Dean D.J., Cartee G.D. Effect of calorie restriction on in vivo] glucose metabolism by individual tissues in rats. Am J Physiol 1999, 276:E728E738.
    • (1999) Am J Physiol , vol.276
    • Wetter, T.J.1    Gazdag, A.C.2    Dean, D.J.3    Cartee, G.D.4
  • 49
    • 0025617479 scopus 로고
    • Naturally occurring fluctuation in dendritic spine density on adult hippocampal pyramidal neurons
    • Woolley C.S., Gould E., Frankfurt M., McEwen B.S. Naturally occurring fluctuation in dendritic spine density on adult hippocampal pyramidal neurons. J Neurosci 1990, 10:4035-4039.
    • (1990) J Neurosci , vol.10 , pp. 4035-4039
    • Woolley, C.S.1    Gould, E.2    Frankfurt, M.3    McEwen, B.S.4
  • 50
    • 0025168942 scopus 로고
    • Exposure to excess glucocorticoids alters dendritic morphology of adult hippocampal pyramidal neurons
    • Woolley C.S., Gould E., McEwen B.S. Exposure to excess glucocorticoids alters dendritic morphology of adult hippocampal pyramidal neurons. Brain Res 1990, 531:225-231.
    • (1990) Brain Res , vol.531 , pp. 225-231
    • Woolley, C.S.1    Gould, E.2    McEwen, B.S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.