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Volumn 25, Issue 29, 2005, Pages 6877-6886

Age-associated alterations of hippocampal place cells are subregion specific

Author keywords

Age associated cognitive impairment; Aging; CA1; CA3; Hippocampus; Place cells; Spatial memory

Indexed keywords

ADOLESCENT; AGED; AGING; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN REGION; CELL SPECIFICITY; CONTROLLED STUDY; HIPPOCAMPUS; INFORMATION PROCESSING; MALE; MEMORY DISORDER; NERVE CELL; NERVE CELL STIMULATION; NONHUMAN; PRIORITY JOURNAL; RAT; SPATIAL MEMORY;

EID: 22544475288     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.1744-05.2005     Document Type: Article
Times cited : (233)

References (63)
  • 1
    • 0018344553 scopus 로고
    • Memory deficits associated with senescence: A neurophysiological and behavioral study in the rat
    • Barnes CA (1979) Memory deficits associated with senescence: a neurophysiological and behavioral study in the rat. J Comp Physiol Psychol 93:74-104.
    • (1979) J Comp Physiol Psychol , vol.93 , pp. 74-104
    • Barnes, C.A.1
  • 2
    • 0028107456 scopus 로고
    • Normal aging: Regionally specific changes in hippocampal synaptic transmission
    • Barnes CA (1994) Normal aging: regionally specific changes in hippocampal synaptic transmission. Trends Neurosci 17:13-18.
    • (1994) Trends Neurosci , vol.17 , pp. 13-18
    • Barnes, C.A.1
  • 3
    • 0019225823 scopus 로고
    • Physiological compensation for loss of afferent synapses in rat hippocampal granule cells during senescence
    • Barnes CA, McNaughton BL (1980) Physiological compensation for loss of afferent synapses in rat hippocampal granule cells during senescence. J Physiol (Lond) 309:473-485.
    • (1980) J Physiol (Lond) , vol.309 , pp. 473-485
    • Barnes, C.A.1    McNaughton, B.L.2
  • 4
    • 0030854720 scopus 로고    scopus 로고
    • Multistability of cognitive maps in the hippocampus of old rats
    • Barnes CA, Suster MS, Shen J, McNaughton BL (1997) Multistability of cognitive maps in the hippocampus of old rats. Nature 388:272-275.
    • (1997) Nature , vol.388 , pp. 272-275
    • Barnes, C.A.1    Suster, M.S.2    Shen, J.3    McNaughton, B.L.4
  • 5
    • 0026143363 scopus 로고
    • Experience-dependent modifications of hippocampal place cell firing
    • Bostock E, Muller RU, Kubie JL (1991) Experience-dependent modifications of hippocampal place cell firing. Hippocampus 1:193-205.
    • (1991) Hippocampus , vol.1 , pp. 193-205
    • Bostock, E.1    Muller, R.U.2    Kubie, J.L.3
  • 6
    • 0028919629 scopus 로고
    • Dentate EEG spikes and associated interneuronal population bursts in the hippocampal hilar region of the rat
    • Bragin A, Jando G, Nadasdy Z, van Landeghem M, Buzsaki G (1995) Dentate EEG spikes and associated interneuronal population bursts in the hippocampal hilar region of the rat. J Neurophysiol 73:1691-1705.
    • (1995) J Neurophysiol , vol.73 , pp. 1691-1705
    • Bragin, A.1    Jando, G.2    Nadasdy, Z.3    Van Landeghem, M.4    Buzsaki, G.5
  • 7
    • 0037439914 scopus 로고    scopus 로고
    • Muscarinic blockade slows and degrades the location-specific firing of hippocampal pyramidal cells
    • Brazhnik ES, Muller RU, Fox SE (2003) Muscarinic blockade slows and degrades the location-specific firing of hippocampal pyramidal cells. J Neurosci 23:611-621.
    • (2003) J Neurosci , vol.23 , pp. 611-621
    • Brazhnik, E.S.1    Muller, R.U.2    Fox, S.E.3
  • 11
    • 0345403571 scopus 로고    scopus 로고
    • Operational dynamics in the hippocampal-entorhinal axis
    • Chrobak JJ, Buzsaki G (1998) Operational dynamics in the hippocampal-entorhinal axis. Neurosci Biobehav Rev 22:303-310.
    • (1998) Neurosci Biobehav Rev , vol.22 , pp. 303-310
    • Chrobak, J.J.1    Buzsaki, G.2
  • 12
    • 0032737984 scopus 로고    scopus 로고
    • Involvement of hippocampal synaptic plasticity in age-related memory decline
    • Foster TC (1999) Involvement of hippocampal synaptic plasticity in age-related memory decline. Brain Res Brain Res Rev 30:236-249.
    • (1999) Brain Res Brain Res Rev , vol.30 , pp. 236-249
    • Foster, T.C.1
  • 13
    • 0030337503 scopus 로고    scopus 로고
    • Interneurons of the hippocampus
    • Freund TF, Buzsaki G (1996) Interneurons of the hippocampus. Hippocampus 6:347-470.
    • (1996) Hippocampus , vol.6 , pp. 347-470
    • Freund, T.F.1    Buzsaki, G.2
  • 15
    • 0024798104 scopus 로고
    • Relationship of age-related decline across several behavioral domains
    • Gallagher M, Burwell RD (1989) Relationship of age-related decline across several behavioral domains. Neurobiol Aging 10:691-708.
    • (1989) Neurobiol Aging , vol.10 , pp. 691-708
    • Gallagher, M.1    Burwell, R.D.2
  • 16
    • 0027214025 scopus 로고
    • Severity of spatial learning impairment in aging: Development of a learning index for performance in the Morris water maze
    • Gallagher M, Burwell R, Burchinal M (1993) Severity of spatial learning impairment in aging: development of a learning index for performance in the Morris water maze. Behav Neurosci 107:618-626.
    • (1993) Behav Neurosci , vol.107 , pp. 618-626
    • Gallagher, M.1    Burwell, R.2    Burchinal, M.3
  • 17
    • 0026938047 scopus 로고
    • Age-related loss of axospinous synapses formed by two afferent systems in the rat dentate gyrus as revealed by the unbiased stereological dissector technique
    • Geinisman Y, de Toledo-Morrell L, Morrell F, Persina IS, Rossi M (1992) Age-related loss of axospinous synapses formed by two afferent systems in the rat dentate gyrus as revealed by the unbiased stereological dissector technique. Hippocampus 2:437-444.
    • (1992) Hippocampus , vol.2 , pp. 437-444
    • Geinisman, Y.1    De Toledo-Morrell, L.2    Morrell, F.3    Persina, I.S.4    Rossi, M.5
  • 18
    • 8844235057 scopus 로고    scopus 로고
    • Ensemble dynamics of hippocampal regions CA3 and CA1
    • Guzowski JF, Knierim JJ, Moser EI (2004) Ensemble dynamics of hippocampal regions CA3 and CA1. Neuron 44:581-584.
    • (2004) Neuron , vol.44 , pp. 581-584
    • Guzowski, J.F.1    Knierim, J.J.2    Moser, E.I.3
  • 19
    • 0029029583 scopus 로고
    • Dynamics of learning and recall at excitatory recurrent synapses and cholinergic modulation in rat hippocampal region CA3
    • Hasselmo ME, Schnell E, Barkai E (1995) Dynamics of learning and recall at excitatory recurrent synapses and cholinergic modulation in rat hippocampal region CA3. J Neurosci 15:5249-5262.
    • (1995) J Neurosci , vol.15 , pp. 5249-5262
    • Hasselmo, M.E.1    Schnell, E.2    Barkai, E.3
  • 20
    • 0035986196 scopus 로고    scopus 로고
    • Cholinergic system regulation of spatial representation by the hippocampus
    • Ikonen S, McMahan R, Gallagher M, Eichenbaum H, Tanila H (2002) Cholinergic system regulation of spatial representation by the hippocampus. Hippocampus 12:386-397.
    • (2002) Hippocampus , vol.12 , pp. 386-397
    • Ikonen, S.1    McMahan, R.2    Gallagher, M.3    Eichenbaum, H.4    Tanila, H.5
  • 21
    • 0027156030 scopus 로고
    • Spatial selectivity of unit activity in the hippocampal granular layer
    • Jung MW, McNaughton BL (1993) Spatial selectivity of unit activity in the hippocampal granular layer. Hippocampus 3:165-182.
    • (1993) Hippocampus , vol.3 , pp. 165-182
    • Jung, M.W.1    McNaughton, B.L.2
  • 22
    • 0034059677 scopus 로고    scopus 로고
    • Reversible inactivation of the hippocampal mossy fiber synapses in mice impairs spatial learning, but neither consolidation nor memory retrieval, in the Morris navigation task
    • Lassalle JM, Bataille T, Halley H (2000) Reversible inactivation of the hippocampal mossy fiber synapses in mice impairs spatial learning, but neither consolidation nor memory retrieval, in the Morris navigation task. Neurobiol Learn Mem 73:243-257.
    • (2000) Neurobiol Learn Mem , vol.73 , pp. 243-257
    • Lassalle, J.M.1    Bataille, T.2    Halley, H.3
  • 23
    • 1542710246 scopus 로고    scopus 로고
    • Encoding versus retrieval of spatial memory: Double dissociation between the dentate gyrus and the perforant path inputs into CA3 in the dorsal hippocampus
    • Lee I, Kesner RP (2004) Encoding versus retrieval of spatial memory: double dissociation between the dentate gyrus and the perforant path inputs into CA3 in the dorsal hippocampus. Hippocampus 14:66-76.
    • (2004) Hippocampus , vol.14 , pp. 66-76
    • Lee, I.1    Kesner, R.P.2
  • 24
    • 2942523944 scopus 로고    scopus 로고
    • A double dissociation between hippocampal subfields: Differential time course of CA3 and CA1 place cells for processing changed environments
    • Lee I, Rao G, Knierim JJ (2004a) A double dissociation between hippocampal subfields: differential time course of CA3 and CA1 place cells for processing changed environments. Neuron 42:803-815.
    • (2004) Neuron , vol.42 , pp. 803-815
    • Lee, I.1    Rao, G.2    Knierim, J.J.3
  • 25
    • 3242799836 scopus 로고    scopus 로고
    • Comparison of population coherence of place cells in hippocampal subfields CA1 and CA3
    • Lee I, Yoganarasimha D, Rao G, Knierim JJ (2004b) Comparison of population coherence of place cells in hippocampal subfields CA1 and CA3. Nature 430:456-459.
    • (2004) Nature , vol.430 , pp. 456-459
    • Lee, I.1    Yoganarasimha, D.2    Rao, G.3    Knierim, J.J.4
  • 27
    • 0028029502 scopus 로고
    • Spatial information content and reliability of hippocampal CA1 neurons: Effects of visual input
    • Markus EJ, Barnes CA, McNaughton BL, Gladden VL, Skaggs WE (1994) Spatial information content and reliability of hippocampal CA1 neurons: effects of visual input. Hippocampus 4:410-421.
    • (1994) Hippocampus , vol.4 , pp. 410-421
    • Markus, E.J.1    Barnes, C.A.2    McNaughton, B.L.3    Gladden, V.L.4    Skaggs, W.E.5
  • 28
    • 0015083717 scopus 로고
    • Simple memory: A theory for archicortex
    • Marr D (1971) Simple memory: a theory for archicortex. Philos Trans R Soc Lond B Biol Sci 262:23-81.
    • (1971) Philos Trans R Soc Lond B Biol Sci , vol.262 , pp. 23-81
    • Marr, D.1
  • 29
    • 0034786874 scopus 로고    scopus 로고
    • Aging and learning-specific changes in single-neuron activity in CA1 hippocampus during rabbit trace eyeblink conditioning
    • McEchron MD, Weible AP, Disterhoft JF (2001) Aging and learning-specific changes in single-neuron activity in CA1 hippocampus during rabbit trace eyeblink conditioning. J Neurophysiol 86:1839-1857.
    • (2001) J Neurophysiol , vol.86 , pp. 1839-1857
    • McEchron, M.D.1    Weible, A.P.2    Disterhoft, J.F.3
  • 30
    • 0023620017 scopus 로고
    • Hippocampal synaptic enhancement and information storage within a distributed memory system
    • McNaughton BL, Morris RGM (1987) Hippocampal synaptic enhancement and information storage within a distributed memory system. Trends Neurosci 10:408-415.
    • (1987) Trends Neurosci , vol.10 , pp. 408-415
    • McNaughton, B.L.1    Morris, R.G.M.2
  • 31
    • 0031455868 scopus 로고    scopus 로고
    • Age and experience-dependent representational reorganization during spatial learning
    • Mizumori SJ, Kalyani A (1997) Age and experience-dependent representational reorganization during spatial learning. Neurobiol Aging 18:651-659.
    • (1997) Neurobiol Aging , vol.18 , pp. 651-659
    • Mizumori, S.J.1    Kalyani, A.2
  • 32
    • 0024329746 scopus 로고
    • Preserved spatial coding in hippocampal CA1 pyramidal cells during reversible suppression of CA3c output: Evidence for pattern completion in hippocampus
    • Mizumori SJ, McNaughton BL, Barnes CA, Fox KB (1989) Preserved spatial coding in hippocampal CA1 pyramidal cells during reversible suppression of CA3c output: evidence for pattern completion in hippocampus. J Neurosci 9:3915-3928.
    • (1989) J Neurosci , vol.9 , pp. 3915-3928
    • Mizumori, S.J.1    McNaughton, B.L.2    Barnes, C.A.3    Fox, K.B.4
  • 33
    • 0029974070 scopus 로고    scopus 로고
    • Redistribution of spatial representation in the hippocampus of aged rats performing a spatial memory task
    • Mizumori SJ, Lavoie AM, Kalyani A (1996) Redistribution of spatial representation in the hippocampus of aged rats performing a spatial memory task. Behav Neurosci 110:1006-1016.
    • (1996) Behav Neurosci , vol.110 , pp. 1006-1016
    • Mizumori, S.J.1    Lavoie, A.M.2    Kalyani, A.3
  • 34
    • 0019957779 scopus 로고
    • Place navigation impaired in rats with hippocampal lesions
    • Morris RG, Garrud P, Rawlins JN, O'Keefe J (1982) Place navigation impaired in rats with hippocampal lesions. Nature 297:681-683.
    • (1982) Nature , vol.297 , pp. 681-683
    • Morris, R.G.1    Garrud, P.2    Rawlins, J.N.3    O'Keefe, J.4
  • 36
    • 0037987979 scopus 로고    scopus 로고
    • Hippocampal CA3 NMDA receptors are crucial for memory acquisition of one-time experience
    • Nakazawa K, Sun LD, Quirk MC, Rondi-Reig L, Wilson MA, Tonegawa S (2003) Hippocampal CA3 NMDA receptors are crucial for memory acquisition of one-time experience. Neuron 38:305-315.
    • (2003) Neuron , vol.38 , pp. 305-315
    • Nakazawa, K.1    Sun, L.D.2    Quirk, M.C.3    Rondi-Reig, L.4    Wilson, M.A.5    Tonegawa, S.6
  • 37
    • 0033232920 scopus 로고    scopus 로고
    • Metabotropic glutamate receptor-mediated hippocampal phosphoinositide turnover is blunted in spatial learning-impaired aged rats
    • Nicolle MM, Colombo PJ, Gallagher M, McKinney M (1999) Metabotropic glutamate receptor-mediated hippocampal phosphoinositide turnover is blunted in spatial learning-impaired aged rats. J Neurosci 19:9604-9610.
    • (1999) J Neurosci , vol.19 , pp. 9604-9610
    • Nicolle, M.M.1    Colombo, P.J.2    Gallagher, M.3    McKinney, M.4
  • 38
    • 0033920579 scopus 로고    scopus 로고
    • Age-related deficits in the ability to encode contextual change: A place cell analysis
    • Oler JA, Markus EJ (2000) Age-related deficits in the ability to encode contextual change: a place cell analysis. Hippocampus 10:338-350.
    • (2000) Hippocampus , vol.10 , pp. 338-350
    • Oler, J.A.1    Markus, E.J.2
  • 39
    • 0028585928 scopus 로고
    • Hippocampal conjunctive encoding, storage, and recall: Avoiding a trade-off
    • O'Reilly RC, McClelland JL (1994) Hippocampal conjunctive encoding, storage, and recall: avoiding a trade-off. Hippocampus 4:661-682.
    • (1994) Hippocampus , vol.4 , pp. 661-682
    • O'Reilly, R.C.1    McClelland, J.L.2
  • 41
    • 0029821150 scopus 로고    scopus 로고
    • Preserved neuron number in the hippocampus of aged rats with spatial learning deficits
    • Rapp PR, Gallagher M (1996) Preserved neuron number in the hippocampus of aged rats with spatial learning deficits. Proc Natl Acad Sci USA 93:9926-9930.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 9926-9930
    • Rapp, P.R.1    Gallagher, M.2
  • 42
    • 0033601731 scopus 로고    scopus 로고
    • Morphometric studies of the aged hippocampus. I. Volumetric analysis in behaviorally characterized rats
    • Rapp PR, Stack EC, Gallagher M (1999) Morphometric studies of the aged hippocampus. I. Volumetric analysis in behaviorally characterized rats. J Comp Neurol 403:459-470.
    • (1999) J Comp Neurol , vol.403 , pp. 459-470
    • Rapp, P.R.1    Stack, E.C.2    Gallagher, M.3
  • 44
    • 0031730368 scopus 로고    scopus 로고
    • Reconciling Barnes et al. (1997) and Tanila et al. (1997a,b)
    • Redish AD, McNaughton BL, Barnes CA (1998) Reconciling Barnes et al. (1997) and Tanila et al. (1997a,b). Hippocampus 8:438-443.
    • (1998) Hippocampus , vol.8 , pp. 438-443
    • Redish, A.D.1    McNaughton, B.L.2    Barnes, C.A.3
  • 45
    • 0037936789 scopus 로고    scopus 로고
    • Impact of aging on hippocampal function: Plasticity, network dynamics, and cognition
    • Rosenzweig ES, Barnes CA (2003) Impact of aging on hippocampal function: plasticity, network dynamics, and cognition. Prog Neurobiol 69:143-179.
    • (2003) Prog Neurobiol , vol.69 , pp. 143-179
    • Rosenzweig, E.S.1    Barnes, C.A.2
  • 47
    • 0033951341 scopus 로고    scopus 로고
    • Contribution of multiple sensory information to place field stability in hippocampal place cells
    • Save E, Nerad L, Poucet B (2000) Contribution of multiple sensory information to place field stability in hippocampal place cells. Hippocampus 10:64-76.
    • (2000) Hippocampus , vol.10 , pp. 64-76
    • Save, E.1    Nerad, L.2    Poucet, B.3
  • 48
    • 16944363524 scopus 로고    scopus 로고
    • The effect of aging on experience-dependent plasticity of hippocampal place cells
    • Shen J, Barnes CA, McNaughton BL, Skaggs WE, Weaver KL (1997) The effect of aging on experience-dependent plasticity of hippocampal place cells. J Neurosci 17:6769-6782.
    • (1997) J Neurosci , vol.17 , pp. 6769-6782
    • Shen, J.1    Barnes, C.A.2    McNaughton, B.L.3    Skaggs, W.E.4    Weaver, K.L.5
  • 49
    • 0001270473 scopus 로고
    • Aninformation theoretic approach to deciphering the hippocampal code
    • (Hanson SJ, Cowan JD, Giles CL, eds). San Mateo, CA: Morgan Kaufman
    • Skaggs WE, McNaughton BL, Gothard KM, Markus, EJ (1993) Aninformation theoretic approach to deciphering the hippocampal code. In: Advances in neural information processing systems (Hanson SJ, Cowan JD, Giles CL, eds), pp 1030-1037. San Mateo, CA: Morgan Kaufman.
    • (1993) Advances in Neural Information Processing Systems , pp. 1030-1037
    • Skaggs, W.E.1    McNaughton, B.L.2    Gothard, K.M.3    Markus, E.J.4
  • 50
    • 2342557824 scopus 로고    scopus 로고
    • Imaging correlates of brain function in monkeys and rats isolates a hippocampal subregion differentially vulnerable to aging
    • Small SA, Chawla MK, Buonocore M, Rapp PR, Barnes CA (2004) Imaging correlates of brain function in monkeys and rats isolates a hippocampal subregion differentially vulnerable to aging. Proc Natl Acad Sci USA 101:7181-7186.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 7181-7186
    • Small, S.A.1    Chawla, M.K.2    Buonocore, M.3    Rapp, P.R.4    Barnes, C.A.5
  • 51
    • 0034279244 scopus 로고    scopus 로고
    • Circuit-specific alterations in hippocampal synaptophysin immunoreactivity predict spatial learning impairment in aged rats
    • Smith TD, Adams MM, Gallagher M, Morrison JH, Rapp PR (2000) Circuit-specific alterations in hippocampal synaptophysin immunoreactivity predict spatial learning impairment in aged rats. J Neurosci 20:6587-6593.
    • (2000) J Neurosci , vol.20 , pp. 6587-6593
    • Smith, T.D.1    Adams, M.M.2    Gallagher, M.3    Morrison, J.H.4    Rapp, P.R.5
  • 52
    • 1842509983 scopus 로고    scopus 로고
    • Aging in the rat hippocampus is associated with widespread reductions in the number of glutamate decarboxylase-67 positive interneurons but not interneuron degeneration
    • Stanley DP, Shetty AK (2004) Aging in the rat hippocampus is associated with widespread reductions in the number of glutamate decarboxylase-67 positive interneurons but not interneuron degeneration. J Neurochem 89:204-216.
    • (2004) J Neurochem , vol.89 , pp. 204-216
    • Stanley, D.P.1    Shetty, A.K.2
  • 54
    • 0030915192 scopus 로고    scopus 로고
    • Brain aging: Changes in the nature of information coding by the hippocampus
    • Tanila H, Shapiro M, Gallagher M, Eichenbaum H (1997a) Brain aging: changes in the nature of information coding by the hippocampus. J Neurosci 17:5155-5166.
    • (1997) J Neurosci , vol.17 , pp. 5155-5166
    • Tanila, H.1    Shapiro, M.2    Gallagher, M.3    Eichenbaum, H.4
  • 55
    • 0030963161 scopus 로고    scopus 로고
    • Brain aging: Impaired coding of novel environmental cues
    • Tanila H, Sipila P, Shapiro M, Eichenbaum H (1997b) Brain aging: impaired coding of novel environmental cues. J Neurosci 17:5167-5174.
    • (1997) J Neurosci , vol.17 , pp. 5167-5174
    • Tanila, H.1    Sipila, P.2    Shapiro, M.3    Eichenbaum, H.4
  • 56
    • 0026849958 scopus 로고
    • Computational constraints suggest the need for two distinct input systems to the hippocampal CA3 network
    • Treves A, Rolls ET (1992) Computational constraints suggest the need for two distinct input systems to the hippocampal CA3 network. Hippocampus 2:189-199.
    • (1992) Hippocampus , vol.2 , pp. 189-199
    • Treves, A.1    Rolls, E.T.2
  • 57
    • 0028109694 scopus 로고
    • Computational analysis of the role of the hippocampus in memory
    • Treves A, Rolls ET (1994) Computational analysis of the role of the hippocampus in memory. Hippocampus 4:374-391.
    • (1994) Hippocampus , vol.4 , pp. 374-391
    • Treves, A.1    Rolls, E.T.2
  • 58
    • 3242802723 scopus 로고    scopus 로고
    • Differences in hippocampal neuronal population responses to modifications of an environmental context: Evidence for distinct, yet complementary, functions of CA3 and CA1 ensembles
    • Vazdarjanova A, Guzowski JF (2004) Differences in hippocampal neuronal population responses to modifications of an environmental context: evidence for distinct, yet complementary, functions of CA3 and CA1 ensembles. J Neurosci 24:6489-6496.
    • (2004) J Neurosci , vol.24 , pp. 6489-6496
    • Vazdarjanova, A.1    Guzowski, J.F.2
  • 59
    • 0345269186 scopus 로고    scopus 로고
    • Rat hippocampal GABAergic molecular markers are differentially affected by ageing
    • Vela J, Gutierrez A, Vitorica J, Ruano D (2003) Rat hippocampal GABAergic molecular markers are differentially affected by ageing. J Neurochem 85:368-377.
    • (2003) J Neurochem , vol.85 , pp. 368-377
    • Vela, J.1    Gutierrez, A.2    Vitorica, J.3    Ruano, D.4
  • 63
    • 0036549053 scopus 로고    scopus 로고
    • Age-related biophysical alterations of hippocampal pyramidal neurons: Implications for learning and memory
    • Wu WW, Oh MM, Disterhoft JF (2002) Age-related biophysical alterations of hippocampal pyramidal neurons: implications for learning and memory. Ageing Res Rev 1:181-207.
    • (2002) Ageing Res Rev , vol.1 , pp. 181-207
    • Wu, W.W.1    Oh, M.M.2    Disterhoft, J.F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.