메뉴 건너뛰기




Volumn 2012, Issue , 2012, Pages

Molecular alterations associated with osteosarcoma development

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOSTATIN; BETA CATENIN; CHEMOKINE RECEPTOR CXCR3; DASATINIB; DISULFIRAM; IMATINIB; INTERLEUKIN 12; INTERLEUKIN 18; OCTREOTIDE; RECOMBINANT ENDOSTATIN; SARACATINIB; SOMATOMEDIN C; SORAFENIB;

EID: 84858121164     PISSN: 1357714X     EISSN: 13691643     Source Type: Journal    
DOI: 10.1155/2012/523432     Document Type: Review
Times cited : (25)

References (182)
  • 2
    • 0020059356 scopus 로고
    • Preoperative chemotherapy for osteogenic sarcoma: Selection of postoperative adjuvant chemotherapy based on the response of the primary tumor to preoperative chemotherapy
    • Rosen G., Caparros B., Huvos A. G., Preoperative chemotherapy for osteogenic sarcoma: selection of postoperative adjuvant chemotherapy based on the response of the primary tumor to preoperative chemotherapy Cancer 1982 49 6 1221 1230 (Pubitemid 12187826)
    • (1982) Cancer , vol.49 , Issue.6 , pp. 1221-1230
    • Rosen, G.1    Caparros, B.2    Huvos, A.G.3
  • 3
    • 33745194182 scopus 로고    scopus 로고
    • Influence of local recurrence on survival in patients with extremity osteosarcoma treated with neoadjuvant chemotherapy: The experience of a single institution with 44 patients
    • Bacci G., Longhi A., Cesari M., Versari M., Bertoni F., Influence of local recurrence on survival in patients with extremity osteosarcoma treated with neoadjuvant chemotherapy: the experience of a single institution with 44 patients Cancer 2006 106 12 2701 2706
    • (2006) Cancer , vol.106 , Issue.12 , pp. 2701-2706
    • Bacci, G.1    Longhi, A.2    Cesari, M.3    Versari, M.4    Bertoni, F.5
  • 4
    • 0031406619 scopus 로고    scopus 로고
    • On the current management of osteosarcoma. A critical evaluation and a proposal for a modified treatment strategy
    • DOI 10.1016/S0959-8049(97)00252-9, PII S0959804997002529
    • Bruland O. S., Pihl A., On the current management of osteosarcoma. A critical evaluation and a proposal for a modified treatment strategy European Journal of Cancer 1997 33 11 1725 1731 (Pubitemid 28129196)
    • (1997) European Journal of Cancer , vol.33 , Issue.11 , pp. 1725-1731
    • Bruland, O.S.1    Pihl, A.2
  • 5
    • 33748156545 scopus 로고    scopus 로고
    • Primary bone osteosarcoma in the pediatric age: State of the art
    • DOI 10.1016/j.ctrv.2006.05.005, PII S0305737206001125
    • Longhi A., Errani C., De Paolis M., Mercuri M., Bacci G., Primary bone osteosarcoma in the pediatric age: state of the art Cancer Treatment Reviews 2006 32 6 423 436 (Pubitemid 44309249)
    • (2006) Cancer Treatment Reviews , vol.32 , Issue.6 , pp. 423-436
    • Longhi, A.1    Errani, C.2    De Paolis, M.3    Mercuri, M.4    Bacci, G.5
  • 6
    • 84878748628 scopus 로고    scopus 로고
    • Bone sarcomas: Pathogenesis and new therapeutic approaches
    • Heymann D., Rédini F., Bone sarcomas: pathogenesis and new therapeutic approaches IBMS 2011 8 9 402 414
    • (2011) IBMS , vol.8 , Issue.9 , pp. 402-414
    • Heymann, D.1    Rédini, F.2
  • 8
    • 0035144560 scopus 로고    scopus 로고
    • Pattern of relapse in patients with osteosarcoma of the extremities treated with neoadjuvant chemotherapy
    • DOI 10.1016/S0959-8049(00)00361-0, PII S0959804900003610
    • Bacci G., Ferrari S., Longhi A., Perin S., Forni C., Fabbri N., Salduca N., Versari M., Smith K. V. J., Pattern of relapse in patients with osteosarcoma of the extremities treated with neoadjuvant chemotherapy European Journal of Cancer 2001 37 1 32 38 (Pubitemid 32119357)
    • (2001) European Journal of Cancer , vol.37 , Issue.1 , pp. 32-38
    • Bacci, G.1    Ferrari, S.2    Longhi, A.3    Perin, S.4    Forni, C.5    Fabbri, N.6    Salduca, N.7    Versari, M.8    Smith, K.V.J.9
  • 9
    • 0017708682 scopus 로고
    • Metastatic osteosarcoma to lung: A clinicopathologic study of surgical biopsies and resections
    • Dunn D., Dehner L. P., Metastatic osteosarcoma to lung: a clinicopathologic study of surgical biopsies and resections Cancer 1977 40 6 3054 3064
    • (1977) Cancer , vol.40 , Issue.6 , pp. 3054-3064
    • Dunn, D.1    Dehner, L.P.2
  • 11
    • 0026846928 scopus 로고
    • The role of angiogenesis in tumor growth
    • Folkman J., The role of angiogenesis in tumor growth Seminars in Cancer Biology 1992 3 2 65 71
    • (1992) Seminars in Cancer Biology , vol.3 , Issue.2 , pp. 65-71
    • Folkman, J.1
  • 12
    • 0023243816 scopus 로고
    • Tumours acquire their vasculature by vessel incorporation, not vessel ingrowth
    • DOI 10.1002/path.1711510413
    • Thompson W. D., Shiach K. J., Fraser R. A., Tumours acquire their vasculature by vessel incorporation, not vessel ingrowth Journal of Pathology 1987 151 4 323 332 (Pubitemid 17071726)
    • (1987) Journal of Pathology , vol.151 , Issue.4 , pp. 323-332
    • Thompson, W.D.1    Shiach, K.J.2    Fraser, R.A.3
  • 13
    • 0021111648 scopus 로고
    • Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid
    • Senger D. R., Galli S. J., Dvorak A. M., Perruzzi C. A., Susan Harvey V., Dvorak H. F., Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid Science 1983 219 4587 983 985
    • (1983) Science , vol.219 , Issue.4587 , pp. 983-985
    • Senger, D.R.1    Galli, S.J.2    Dvorak, A.M.3    Perruzzi, C.A.4    Susan Harvey, V.5    Dvorak, H.F.6
  • 14
    • 0024818355 scopus 로고
    • Vascular endothelial growth factor is a secreted angiogenic mitogen
    • Leung D. W., Cachianes G., Kuang W. J., Goeddel D. V., Ferrara N., Vascular endothelial growth factor is a secreted angiogenic mitogen Science 1989 246 4935 1306 1309 (Pubitemid 20066716)
    • (1989) Science , vol.246 , Issue.4935 , pp. 1306-1309
    • Leung, D.W.1    Cachianes, G.2    Kuang, W.-J.3    Goeddel, D.V.4    Ferrara, N.5
  • 15
    • 34248594553 scopus 로고    scopus 로고
    • Metastasis: Recent discoveries and novel treatment strategies
    • DOI 10.1016/S0140-6736(07)60781-8, PII S0140673607607818
    • Eccles S. A., Welch D. R., Metastasis: recent discoveries and novel treatment strategies The Lancet 2007 369 9574 1742 1757 (Pubitemid 46755391)
    • (2007) Lancet , vol.369 , Issue.9574 , pp. 1742-1757
    • Eccles, S.A.1    Welch, D.R.2
  • 16
    • 33746851956 scopus 로고    scopus 로고
    • Tumor metastasis: Mechanistic insights and clinical challenges
    • DOI 10.1038/nm1469, PII NM1469
    • Steeg P. S., Tumor metastasis: mechanistic insights and clinical challenges Nature Medicine 2006 12 8 895 904 (Pubitemid 44175140)
    • (2006) Nature Medicine , vol.12 , Issue.8 , pp. 895-904
    • Steeg, P.S.1
  • 17
    • 33846044750 scopus 로고    scopus 로고
    • Bone marrow cells in the 'pre-metastatic niche': Within bone and beyond
    • DOI 10.1007/s10555-006-9036-9, Special issue on Bone Metastasis and Cancer
    • Kaplan R. N., Psaila B., Lyden D., Bone marrow cells in the pre-metastatic niche: within bone and beyond Cancer and Metastasis Reviews 2006 25 4 521 529 (Pubitemid 46071861)
    • (2006) Cancer and Metastasis Reviews , vol.25 , Issue.4 , pp. 521-529
    • Kaplan, R.N.1    Psaila, B.2    Lyden, D.3
  • 21
    • 66749098832 scopus 로고    scopus 로고
    • Basement membrane proteoglycans: Modulators par excellence of cancer growth and angiogenesis
    • Iozzo R. V., Zoeller J. J., Nystrm A., Basement membrane proteoglycans: modulators par excellence of cancer growth and angiogenesis Molecules and Cells 2009 27 5 503 513
    • (2009) Molecules and Cells , vol.27 , Issue.5 , pp. 503-513
    • Iozzo, R.V.1    Zoeller, J.J.2    Nystrm, A.3
  • 24
    • 0031873335 scopus 로고    scopus 로고
    • Expression of transforming growth factor β isoforms in osteosarcoma variants: Association of TGFβ1 with high-grade osteosarcomas
    • DOI 10.1002/(SICI)1096-9896(199807)185:3<284::AID-PATH94>3.0.CO;2-Z
    • Franchi A., Arganini L., Baroni G., Calzolari A., Capanna R., Campanacci D., Caldora P., Masi L., Brandi M. L., Zampi G., Expression of transforming growth factor isoforms in osteosarcoma variants: association of TGF 1 with high-grade osteosarcomas Journal of Pathology 1998 185 3 284 289 (Pubitemid 28320050)
    • (1998) Journal of Pathology , vol.185 , Issue.3 , pp. 284-289
    • Franchi, A.1    Arganini, L.2    Baroni, G.3    Calzolari, A.4    Capanna, R.5    Campanacci, D.6    Caldora, P.7    Masi, L.8    Brandi, M.L.9    Zampi, G.10
  • 30
    • 0027970092 scopus 로고
    • Angiostatin: A novel angiogenesis inhibitor that mediates the suppression of metastases by a Lewis lung carcinoma
    • DOI 10.1016/0092-8674(94)90200-3
    • O'Reilly M. S., Holmgren L., Shing Y., Chen C., Rosenthal R. A., Moses M., Lane W. S., Cao Y., Sage E. H., Folkman J., Angiostatin: a novel angiogenesis inhibitor that mediates the suppression of metastases by a Lewis lung carcinoma Cell 1994 79 2 315 328 (Pubitemid 24324921)
    • (1994) Cell , vol.79 , Issue.2 , pp. 315-328
    • O'Reilly, M.S.1    Holmgren, L.2    Shing, Y.3    Chen, C.4    Rosenthal, R.A.5    Moses, M.6    Lane, W.S.7    Cao, Y.8    Helene Sage, E.9    Folkman, J.10
  • 35
    • 0034655135 scopus 로고    scopus 로고
    • Synergy between angiostatin and endostatin: Inhibition of ovarian cancer growth
    • Yokoyama Y., Dhanabal M., Griffioen A. W., Sukhatme V. P., Ramakrishnan S., Synergy between angiostatin and endostatin: inhibition of ovarian cancer growth Cancer Research 2000 60 8 2190 2196 (Pubitemid 30225182)
    • (2000) Cancer Research , vol.60 , Issue.8 , pp. 2190-2196
    • Yokoyama, Y.1    Dhanabal, M.2    Griffioen, A.W.3    Sukhatme, V.P.4    Ramakrishnan, S.5
  • 36
    • 0035887379 scopus 로고    scopus 로고
    • Continuous administration of endostatin by intraperitoneally implanted osmotic pump improves the efficacy and potency of therapy in a mouse xenograft tumor model
    • Kisker O., Becker C. M., Prox D., Fannon M., D'Amato R., Flynn E., Fogler W. E., Sim B. K. L., Allred E. N., Pirie-Shepherd S. R., Folkman J., Continuous administration of endostatin by intraperitoneally implanted osmotic pump improves the efficacy and potency of therapy in a mouse xenograft tumor model Cancer Research 2001 61 20 7669 7674 (Pubitemid 32995064)
    • (2001) Cancer Research , vol.61 , Issue.20 , pp. 7669-7674
    • Kisker, O.1    Becker, C.M.2    Prox, D.3    Fannon, M.4    D'Amato, R.5    Flynn, E.6    Fogler, W.E.7    Sim, B.K.L.8    Allred, E.N.9    Pirie-Shepherd, S.R.10    Folkman, J.11
  • 37
    • 0036275675 scopus 로고    scopus 로고
    • Adeno-associated virus-mediated gene transfer of endostatin inhibits angiogenesis and tumor growth in vivo
    • DOI 10.1038/sj.cgt.7700463
    • Shi W., Teschendorf C., Muzyczka N., Siemann D. W., Adeno-associated virus-mediated gene transfer of endostatin inhibits angiogenesis and tumor growth in vivo Cancer Gene Therapy 2002 9 6 513 521 (Pubitemid 34569034)
    • (2002) Cancer Gene Therapy , vol.9 , Issue.6 , pp. 513-521
    • Shi, W.1    Teschendorf, C.2    Muzyczka, N.3    Siemann, D.W.4
  • 45
    • 33846882630 scopus 로고    scopus 로고
    • Molecular pathogenesis of osteosarcoma
    • DOI 10.1089/dna.2006.0505
    • Kansara M., Thomas D. M., Molecular pathogenesis of osteosarcoma DNA and Cell Biology 2007 26 1 1 18 (Pubitemid 46219587)
    • (2007) DNA and Cell Biology , vol.26 , Issue.1 , pp. 1-18
    • Kansara, M.1    Thomas, D.M.2
  • 46
    • 71549169276 scopus 로고    scopus 로고
    • Silencing of calpain expression reduces the metastatic potential of human osteosarcoma cells
    • Fan D. G., Dai J. Y., Tang J., Wu M. M., Sun S. G., Jiang J. L., Fan Q. Y., Silencing of calpain expression reduces the metastatic potential of human osteosarcoma cells Cell Biology International 2009 33 12 1263 1267
    • (2009) Cell Biology International , vol.33 , Issue.12 , pp. 1263-1267
    • Fan, D.G.1    Dai, J.Y.2    Tang, J.3    Wu, M.M.4    Sun, S.G.5    Jiang, J.L.6    Fan, Q.Y.7
  • 47
    • 33745182564 scopus 로고    scopus 로고
    • PI3-K/Akt-mediated anoikis resistance of human osteosarcoma cells requires Src activation
    • DOI 10.1016/j.ejca.2006.03.007, PII S0959804906002693
    • Daz-Montero C. M., Wygant J. N., McIntyre B. W., PI3-K/Akt-mediated anoikis resistance of human osteosarcoma cells requires Src activation European Journal of Cancer 2006 42 10 1491 1500 (Pubitemid 43903158)
    • (2006) European Journal of Cancer , vol.42 , Issue.10 , pp. 1491-1500
    • Diaz-Montero, C.M.1    Wygant, J.N.2    McIntyre, B.W.3
  • 48
    • 66149192409 scopus 로고    scopus 로고
    • Inhibition of Src phosphorylation alters metastatic potential of osteosarcoma in vitro but not in vivo
    • Hingorani P., Zhang W., Gorlick R., Kolb E. A., Inhibition of Src phosphorylation alters metastatic potential of osteosarcoma in vitro but not in vivo Clinical Cancer Research 2009 15 10 3416 3422
    • (2009) Clinical Cancer Research , vol.15 , Issue.10 , pp. 3416-3422
    • Hingorani, P.1    Zhang, W.2    Gorlick, R.3    Kolb, E.A.4
  • 50
    • 77949667984 scopus 로고    scopus 로고
    • Wnt inhibitory factor 1 decreases tumorigenesis and metastasis in osteosarcoma
    • Rubin E. M., Guo Y., Tu K., Xie J., Zi X., Hoang B. H., Wnt inhibitory factor 1 decreases tumorigenesis and metastasis in osteosarcoma Molecular Cancer Therapeutics 2010 9 3 731 741
    • (2010) Molecular Cancer Therapeutics , vol.9 , Issue.3 , pp. 731-741
    • Rubin, E.M.1    Guo, Y.2    Tu, K.3    Xie, J.4    Zi, X.5    Hoang, B.H.6
  • 51
    • 34447279476 scopus 로고    scopus 로고
    • Blocking Wnt/LRP5 signaling by a soluble receptor modulates the epithelial to mesenchymal transition and suppresses met and metalloproteinases in osteosarcoma Saos-2 cells
    • DOI 10.1002/jor.20356
    • Guo Y., Zi X., Koontz Z., Kim A., Xie J., Gorlick R., Holcombe R. F., Hoang B. H., Blocking Wnt/LRP5 signaling by a soluble receptor modulates the epithelial to mesenchymal transition and suppresses met and metalloproteinases in osteosarcoma Saos-2 cells Journal of Orthopaedic Research 2007 25 7 964 971 (Pubitemid 47046444)
    • (2007) Journal of Orthopaedic Research , vol.25 , Issue.7 , pp. 964-971
    • Guo, Y.1    Zi, X.2    Koontz, Z.3    Kim, A.4    Xie, J.5    Gorlick, R.6    Holcombe, R.F.7    Hoang, B.H.8
  • 53
    • 77953674754 scopus 로고    scopus 로고
    • How the NOTCH pathway contributes to the ability of osteosarcoma cells to metastasize
    • Hughes D. P. M., How the NOTCH pathway contributes to the ability of osteosarcoma cells to metastasize Cancer Treatment and Research 2009 152 479 496
    • (2009) Cancer Treatment and Research , vol.152 , pp. 479-496
    • Hughes, D.P.M.1
  • 55
    • 49649103793 scopus 로고    scopus 로고
    • Critical role of notch signaling in osteosarcoma invasion and metastasis
    • Zhang P., Yang Y., Zweidler-McKay P. A., Hughes D. P. M., Critical role of notch signaling in osteosarcoma invasion and metastasis Clinical Cancer Research 2008 14 10 2962 2969
    • (2008) Clinical Cancer Research , vol.14 , Issue.10 , pp. 2962-2969
    • Zhang, P.1    Yang, Y.2    Zweidler-Mckay, P.A.3    Hughes, D.P.M.4
  • 56
    • 0034987229 scopus 로고    scopus 로고
    • Expression of MMP2, MMP9, MT1-MMP, TIMP1, and TIMP2 mRNA in valvular lesions of the heart
    • Soini Y., Satta J., Mtt M., Autio-Harmainen H., Expression of MMP2, MMP9, MT1-MMP, TIMP1, and TIMP2 mRNA in valvular lesions of the heart The Journal of Pathology 2001 194 2 225 231
    • (2001) The Journal of Pathology , vol.194 , Issue.2 , pp. 225-231
    • Soini, Y.1    Satta, J.2    Mtt, M.3    Autio-Harmainen, H.4
  • 57
    • 0036581406 scopus 로고    scopus 로고
    • Relationship between expression of matrix metalloproteinase-2 and matrix metalloproteinase-9 and invasion ability of cervical cancer cells
    • Kato Y., Yamashita T., Ishikawa M., Relationship between expression of matrix metalloproteinase-2 and matrix metalloproteinase-9 and invasion ability of cervical cancer cells Oncology reports 2002 9 3 565 569
    • (2002) Oncology Reports , vol.9 , Issue.3 , pp. 565-569
    • Kato, Y.1    Yamashita, T.2    Ishikawa, M.3
  • 58
    • 0033752746 scopus 로고    scopus 로고
    • Functional significance of MMP-9 in tumor necrosis factor-induced proliferation and branching morphogenesis of mammary epithelial cells
    • Lee P. P. H., Hwang J. J., Murphy G., Ip M. M., Functional significance of MMP-9 in tumor necrosis factor-induced proliferation and branching morphogenesis of mammary epithelial cells Endocrinology 2000 141 10 3764 3773
    • (2000) Endocrinology , vol.141 , Issue.10 , pp. 3764-3773
    • Lee, P.P.H.1    Hwang, J.J.2    Murphy, G.3    Ip, M.M.4
  • 59
    • 33744457678 scopus 로고    scopus 로고
    • Trypsin in colorectal cancer: Molecular biological mechanisms of proliferation, invasion, and metastasis
    • DOI 10.1002/path.1999
    • Soreide K., Janssen E. A., Kmer H., Baak J. P. A., Trypsin in colorectal cancer: molecular biological mechanisms of proliferation, invasion, and metastasis Journal of Pathology 2006 209 2 147 156 (Pubitemid 43805409)
    • (2006) Journal of Pathology , vol.209 , Issue.2 , pp. 147-156
    • Soreide, K.1    Janssen, E.A.2    Komer, H.3    Baak, J.P.A.4
  • 60
    • 1942454714 scopus 로고    scopus 로고
    • Alendronate Regulates Cell Invasion and MMP-2 Secretion in Human Osteosarcoma Cell Lines
    • DOI 10.1002/pbc.20019
    • Cheng Y. Y., Huang L., Lee K. M., Li K., Kumta S. M., Alendronate regulates cell invasion and MMP-2 secretion in human osteosarcoma cell lines Pediatric Blood and Cancer 2004 42 5 410 415 (Pubitemid 38524469)
    • (2004) Pediatric Blood and Cancer , vol.42 , Issue.5 , pp. 410-415
    • Cheng, Y.Y.1    Huang, L.2    Lee, K.M.3    Li, K.4    Kumta, S.M.5
  • 63
    • 3042796964 scopus 로고    scopus 로고
    • Bisphosphonates: New therapeutic agents for the treatment of bone tumors
    • DOI 10.1016/j.molmed.2004.05.007, PII S1471491404001297
    • Heymann D., Ory B., Gouin F., Green J. R., Rédini F., Bisphosphonates: new therapeutic agents for the treatment of bone tumors Trends in Molecular Medicine 2004 10 7 337 343 (Pubitemid 38881523)
    • (2004) Trends in Molecular Medicine , vol.10 , Issue.7 , pp. 337-343
    • Heymann, D.1    Ory, B.2    Gouin, F.3    Green, J.R.4    Redini, F.5
  • 66
    • 42949117323 scopus 로고    scopus 로고
    • Roles of Wnt signalling in bone growth, remodelling, skeletal disorders and fracture repair
    • DOI 10.1002/jcp.21342
    • Macsai C. E., Foster B. K., Xian C. J., Roles of Wnt signalling in bone growth, remodelling, skeletal disorders and fracture repair Journal of Cellular Physiology 2008 215 3 578 587 (Pubitemid 351632678)
    • (2008) Journal of Cellular Physiology , vol.215 , Issue.3 , pp. 578-587
    • Macsai, C.E.1    Foster, B.K.2    Xian, C.J.3
  • 68
    • 0038783316 scopus 로고    scopus 로고
    • Secreted antagonists of the Wnt signalling pathway
    • DOI 10.1242/jcs.00623
    • Kawano Y., Kypta R., Secreted antagonists of the Wnt signalling pathway Journal of Cell Science 2003 116 13 2627 2634 (Pubitemid 36857216)
    • (2003) Journal of Cell Science , vol.116 , Issue.13 , pp. 2627-2634
    • Kawano, Y.1    Kypta, R.2
  • 69
    • 34250823973 scopus 로고    scopus 로고
    • Minireview: Targeting the Wnt/β-catenin pathway to regulate bone formation in the adult skeleton
    • DOI 10.1210/en.2007-0270
    • Baron R., Rawadi G., Minireview: targeting the Wnt/ -catenin pathway to regulate bone formation in the adult skeleton Endocrinology 2007 148 6 2635 2643 (Pubitemid 46984775)
    • (2007) Endocrinology , vol.148 , Issue.6 , pp. 2635-2643
    • Baron, R.1    Rawadi, G.2
  • 72
    • 0033119801 scopus 로고    scopus 로고
    • β-catenin regulates expression of cyclin D1 in colon carcinoma cells
    • DOI 10.1038/18884
    • Tetsu O., McCormick F., -catenin regulates expression of cyclin D1 in colon carcinoma cells Nature 1999 398 6726 422 426 (Pubitemid 29180374)
    • (1999) Nature , vol.398 , Issue.6726 , pp. 422-426
    • Tetsu, O.1    McCormick, F.2
  • 74
  • 75
    • 0038498213 scopus 로고    scopus 로고
    • Survivin and molecular pathogenesis of colorectal cancer
    • DOI 10.1016/S0140-6736(03)13910-4
    • Kim P. J., Plescia J., Clevers H., Fearon E. R., Altieri D. C., Survivin and molecular pathogenesis of colorectal cancer The Lancet 2003 362 9379 205 209 (Pubitemid 36859937)
    • (2003) Lancet , vol.362 , Issue.9379 , pp. 205-209
    • Kim, P.J.1    Plescia, J.2    Clevers, H.3    Fearon, E.R.4    Altieri, D.C.5
  • 77
    • 0142029993 scopus 로고    scopus 로고
    • Cytoplasmic and/or nuclear staining of beta-catenin is associated with lung metastasis
    • DOI 10.1023/A:1025821229013
    • Iwaya K., Ogawa H., Kuroda M., Izumi M., Ishida T., Mukai K., Cytoplasmic and/or nuclear staining of beta-catenin is associated with lung metastasis Clinical and Experimental Metastasis 2003 20 6 525 529 (Pubitemid 37297180)
    • (2003) Clinical and Experimental Metastasis , vol.20 , Issue.6 , pp. 525-529
    • Iwaya, K.1    Ogawa, H.2    Kuroda, M.3    Izumi, M.4    Ishida, T.5    Mukai, K.6
  • 79
    • 0742287878 scopus 로고    scopus 로고
    • Expression of LDL receptor-related protein 5 (LRP5) as a novel marker for disease progression in high-grade osteosarcoma
    • DOI 10.1002/ijc.11677
    • Hoang B. H., Kubo T., Healey J. H., Sowers R., Mazza B., Yang R., Huvos A. G., Meyers P. A., Gorlick R., Expression of LDL receptor-related protein 5 (LRP5) as a novel marker for disease progression in high-grade osteosarcoma International Journal of Cancer 2004 109 1 106 111 (Pubitemid 38160669)
    • (2004) International Journal of Cancer , vol.109 , Issue.1 , pp. 106-111
    • Hoang, B.H.1    Kubo, T.2    Healey, J.H.3    Sowers, R.4    Mazza, B.5    Yang, R.6    Huvos, A.G.7    Meyers, P.A.8    Gorlick, R.9
  • 80
    • 9244240664 scopus 로고    scopus 로고
    • Dickkopf 3 Inhibits Invasion and Motility of Saos-2 Osteosarcoma Cells by Modulating the Wnt-β-Catenin Pathway
    • DOI 10.1158/0008-5472.CAN-03-1952
    • Hoang B. H., Kubo T., Healey J. H., Yang R., Nathan S. S., Kolb E. A., Mazza B., Meyers P. A., Gorlick R., Dickkopf 3 inhibits invasion and motility of Saos-2 osteosarcoma cells by modulating the Wnt- -catenin pathway Cancer Research 2004 64 8 2734 2739 (Pubitemid 38500609)
    • (2004) Cancer Research , vol.64 , Issue.8 , pp. 2734-2739
    • Hoang, B.H.1    Kubo, T.2    Healey, J.H.3    Yang, R.4    Nathan, S.S.5    Kolb, E.A.6    Mazza, B.7    Meyers, P.A.8    Gorlick, R.9
  • 81
    • 0033895709 scopus 로고    scopus 로고
    • Wnt signaling and cancer
    • Polakis P., Wnt signaling and cancer Genes and Development 2000 14 15 1837 1851 (Pubitemid 30639518)
    • (2000) Genes and Development , vol.14 , Issue.15 , pp. 1837-1851
    • Polakis, P.1
  • 82
    • 77954375987 scopus 로고    scopus 로고
    • Antitumor activity of natural compounds, curcumin and PKF118-310, as Wnt/ -catenin antagonists against human osteosarcoma cells
    • Leow P. C., Tian Q., Ong Z. Y., Yang Z., Ee P. L. R., Antitumor activity of natural compounds, curcumin and PKF118-310, as Wnt/ -catenin antagonists against human osteosarcoma cells Investigational New Drugs 2010 28 6 766 782
    • (2010) Investigational New Drugs , vol.28 , Issue.6 , pp. 766-782
    • Leow, P.C.1    Tian, Q.2    Ong, Z.Y.3    Yang, Z.4    Ee, P.L.R.5
  • 85
    • 33745634864 scopus 로고    scopus 로고
    • Inactivation of Wnt inhibitory factor-1 (WIF1) expression by epigenetic silencing is a common event in breast cancer
    • DOI 10.1093/carcin/bgi379
    • Ai L., Tao Q., Zhong S., Fields C. R., Kim W. J., Lee M. W., Cui Y., Brown K. D., Robertson K. D., Inactivation of Wnt inhibitory factor-1 (WIF1) expression by epigenetic silencing is a common event in breast cancer Carcinogenesis 2006 27 7 1341 1348 (Pubitemid 43985409)
    • (2006) Carcinogenesis , vol.27 , Issue.7 , pp. 1341-1348
    • Ai, L.1    Tao, Q.2    Zhong, S.3    Fields, C.R.4    Kim, W.-J.5    Lee, M.W.6    Cui, Y.7    Brown, K.D.8    Robertson, K.D.9
  • 86
    • 32944481037 scopus 로고    scopus 로고
    • Chemical genomic screening for methylation-silenced genes in gastric cancer cell lines using 5-aza-2′-deoxycytidine treatment and oligonucleotide microarray
    • DOI 10.1111/j.1349-7006.2006.00136.x
    • Yamashita S., Tsujino Y., Moriguchi K., Tatematsu M., Ushijima T., Chemical genomic screening for methylation-silenced genes in gastric cancer cell lines using 5-aza- 2′ -deoxycytidine treatment and oligonucleotide microarray Cancer Science 2006 97 1 64 71 (Pubitemid 43257029)
    • (2006) Cancer Science , vol.97 , Issue.1 , pp. 64-71
    • Yamashita, S.1    Tsujino, Y.2    Moriguchi, K.3    Tatematsu, M.4    Ushijima, T.5
  • 87
    • 0033617522 scopus 로고    scopus 로고
    • Notch signaling: Cell fate control and signal integration in development
    • DOI 10.1126/science.284.5415.770
    • Artavanis-Tsakonas S., Rand M. D., Lake R. J., Notch signaling: cell fate control and signal integration in development Science 1999 284 5415 770 776 (Pubitemid 29291335)
    • (1999) Science , vol.284 , Issue.5415 , pp. 770-776
    • Artavanis-Tsakonas, S.1    Rand, M.D.2    Lake, R.J.3
  • 88
    • 64249172203 scopus 로고    scopus 로고
    • The canonical notch signaling pathway: Unfolding the activation mechanism
    • Kopan R., Ilagan M. X., The canonical notch signaling pathway: unfolding the activation mechanism Cell 2009 137 2 216 233
    • (2009) Cell , vol.137 , Issue.2 , pp. 216-233
    • Kopan, R.1    Ilagan, M.X.2
  • 89
    • 0037363922 scopus 로고    scopus 로고
    • HES and HERP families: Multiple effectors of the Notch signaling pathway
    • DOI 10.1002/jcp.10208
    • Iso T., Kedes L., Hamamori Y., HES and HERP families: multiple effectors of the Notch signaling pathway Journal of Cellular Physiology 2003 194 3 237 255 (Pubitemid 36176887)
    • (2003) Journal of Cellular Physiology , vol.194 , Issue.3 , pp. 237-255
    • Iso, T.1    Kedes, L.2    Hamamori, Y.3
  • 91
    • 0027251468 scopus 로고
    • Identification of two juxtamembrane autophosphorylation sites in the PGDF β-receptor; Involvement in the interaction with Src family tyrosine kinases
    • Mori S., Ronnstrand L., Yokote K., Engstrom A., Courtneidge S. A., Claesson-Welsh L., Heldin C. H., Identification of two juxtamembrane autophosphorylation sites in the PGDF -receptor; Involvement in the interaction with Src family tyrosine kinases The EMBO Journal 1993 12 6 2257 2264 (Pubitemid 23194175)
    • (1993) EMBO Journal , vol.12 , Issue.6 , pp. 2257-2264
    • Mori, S.1    Ronnstrand, L.2    Yokote, K.3    Engstrom, A.4    Courtneidge, S.A.5    Claesson-Welsh, L.6    Heldin, C.-H.7
  • 92
    • 7944233251 scopus 로고    scopus 로고
    • The interplay between Src and integrins in normal and tumor biology
    • DOI 10.1038/sj.onc.1208080
    • Playford M. P., Schaller M. D., The interplay between Src and integrins in normal and tumor biology Oncogene 2004 23 48 7928 7946 (Pubitemid 39468852)
    • (2004) Oncogene , vol.23 , Issue.48 REV. ISS. 7 , pp. 7928-7946
    • Playford, M.P.1    Schaller, M.D.2
  • 94
    • 26444468152 scopus 로고    scopus 로고
    • Dasatinib (BMS-354825) tyrosine kinase inhibitor suppresses invasion and induces cell cycle arrest and apoptosis of head and neck squamous cell carcinoma and non-small cell lung cancer cells
    • 19 I, DOI 10.1158/1078-0432.CCR-05-0757
    • Johnson F. M., Saigal B., Talpaz M., Donato N. J., Dasatinib (BMS-354825) tyrosine kinase inhibitor suppresses invasion and induces cell cycle arrest and apoptosis of head and neck squamous cell carcinoma and non-small cell lung cancer cells Clinical Cancer Research 2005 11 19, part 1 6924 6932 (Pubitemid 41428750)
    • (2005) Clinical Cancer Research , vol.11 , pp. 6924-6932
    • Johnson, F.M.1    Saigal, B.2    Talpaz, M.3    Donato, N.J.4
  • 95
    • 31544459272 scopus 로고    scopus 로고
    • Dasatinib (BMS-354825), a dual SRC/ABL kinase inhibitor, inhibits the kinase activity of wild-type, juxtamembrane, and activation loop mutant KIT isoforms associated with human malignancies
    • DOI 10.1158/0008-5472.CAN-05-2050
    • Schittenhelm M. M., Shiraga S., Schroeder A., Corbin A. S., Griffith D., Lee F. Y., Bokemeyer C., Deininger M. W. N., Druker B. J., Heinrich M. C., Dasatinib (BMS-354825), a dual SRC/ABL kinase inhibitor, inhibits the kinase activity of wild-type, juxtamembrane, and activation loop mutant KIT isoforms associated with human malignancies Cancer Research 2006 66 1 473 481 (Pubitemid 43166056)
    • (2006) Cancer Research , vol.66 , Issue.1 , pp. 473-481
    • Schittenhelm, M.M.1    Shiraga, S.2    Schroeder, A.3    Corbin, A.S.4    Griffith, D.5    Lee, F.Y.6    Bokemeyer, C.7    Deininger, M.W.N.8    Druker, B.J.9    Heinrich, M.C.10
  • 96
    • 34047265691 scopus 로고    scopus 로고
    • Dasatinib inhibits migration and invasion in diverse human sarcoma cell lines and induces apoptosis in bone sarcoma cells dependent on Src kinase for survival
    • DOI 10.1158/0008-5472.CAN-06-3469
    • Shor A. C., Keschman E. A., Lee F. Y., Muro-Cacho C., Letson G. D., Trent J. C., Pledger W. J., Jove R., Dasatinib inhibits migration and invasion in diverse human sarcoma cell lines and induces apoptosis in bone sarcoma cells dependent on Src kinase for survival Cancer Research 2007 67 6 2800 2808 (Pubitemid 46548969)
    • (2007) Cancer Research , vol.67 , Issue.6 , pp. 2800-2808
    • Shor, A.C.1    Keschman, E.A.2    Lee, F.Y.3    Muro-Cacho, C.4    Letson, G.D.5    Trent, J.C.6    Pledger, W.J.7    Jove, R.8
  • 97
    • 0032476609 scopus 로고    scopus 로고
    • Fas and Fas ligand interactions suppress melanoma lung metastasis
    • DOI 10.1084/jem.188.9.1717
    • Owen-Schaub L. B., Van Golen K. L., Hill L. L., Price J. E., Fas and Fas ligand interactions suppress melanoma lung metastasis Journal of Experimental Medicine 1998 188 9 1717 1723 (Pubitemid 28516116)
    • (1998) Journal of Experimental Medicine , vol.188 , Issue.9 , pp. 1717-1723
    • Owen-Schaub, L.B.1    Van Golen, K.L.2    Hill, L.L.3    Price, J.E.4
  • 98
    • 0032532283 scopus 로고    scopus 로고
    • Molecular mechanisms of immune-mediated lysis of murine renal cancer: Differential contributions of perforin-dependent versus fas-mediated pathways in lysis by NK and T cells
    • Sayers T. J., Brooks A. D., Lee J. K., Fenton R. G., Komschlies K. L., Wigginton J. M., Winkler-Pickett R., Wiltrout R. H., Molecular mechanisms of immune-mediated lysis of murine renal cancer: differential contributions of perforin-dependent versus fas-mediated pathways in lysis by NK and T cells Journal of Immunology 1998 161 8 3957 3965 (Pubitemid 28468972)
    • (1998) Journal of Immunology , vol.161 , Issue.8 , pp. 3957-3965
    • Sayers, T.J.1    Brooks, A.D.2    Lee, J.-K.3    Fenton, R.G.4    Komschlies, K.L.5    Wigginton, J.M.6    Winkler-Pickett, R.7    Wiltrout, R.H.8
  • 101
    • 0036636786 scopus 로고    scopus 로고
    • Fas expression inversely correlates with metastatic potential in osteosarcoma cells
    • Worth L. L., Lafleur E. A., Jia S. F., Kleinerman E. S., Fas expression inversely correlates with metastatic potential in osteosarcoma cells Oncology Reports 2002 9 4 823 827
    • (2002) Oncology Reports , vol.9 , Issue.4 , pp. 823-827
    • Worth, L.L.1    Lafleur, E.A.2    Jia, S.F.3    Kleinerman, E.S.4
  • 104
    • 60149085396 scopus 로고    scopus 로고
    • The many roles of FAS receptor signaling in the immune system
    • Strasser A., Jost P. J., Nagata S., The many roles of FAS receptor signaling in the immune system Immunity 2009 30 2 180 192
    • (2009) Immunity , vol.30 , Issue.2 , pp. 180-192
    • Strasser, A.1    Jost, P.J.2    Nagata, S.3
  • 105
    • 0036547417 scopus 로고    scopus 로고
    • Death and anti-death: Tumour resistance to apoptosis
    • Igney F. H., Krammer P. H., Death and anti-death: tumour resistance to apoptosis Nature Reviews Cancer 2002 2 4 277 288 (Pubitemid 37328781)
    • (2002) Nature Reviews Cancer , vol.2 , Issue.4 , pp. 277-288
    • Igney, F.H.1    Krammer, P.H.2
  • 107
    • 35948951989 scopus 로고    scopus 로고
    • Fas-negative osteosarcoma tumor cells are selected during metastasis to the lungs: The role of the fas pathwayin the metastatic process of osteosarcoma
    • DOI 10.1158/1541-7786.MCR-07-0007
    • Koshkina N. V., Khanna C., Mendoza A., Guan H., DeLauter L., Kleinerman E. S., Fas-negative osteosarcoma tumor cells are selected during metastasis to the lungs: the role of the fas pathwayin the metastatic process of osteosarcoma Molecular Cancer Research 2007 5 10 991 999 (Pubitemid 350070755)
    • (2007) Molecular Cancer Research , vol.5 , Issue.10 , pp. 991-999
    • Koshkina, N.V.1    Khanna, C.2    Mendoza, A.3    Guan, H.4    DeLauter, L.5    Kleinerman, E.S.6
  • 108
    • 0035872424 scopus 로고    scopus 로고
    • Interleukin (IL)-12 and IL-12 gene transfer up-regulate Fas expression in human osteosarcoma and breast cancer cells
    • Lafleur E. A., Jia S. F., Worth L. L., Zhou Z., Owen-Schaub L. B., Kleinerman E. S., Interleukin (IL)-12 and IL-12 gene transfer up-regulate Fas expression in human osteosarcoma and breast cancer cells Cancer Research 2001 61 10 4066 4071 (Pubitemid 32720972)
    • (2001) Cancer Research , vol.61 , Issue.10 , pp. 4066-4071
    • Lafleur, E.A.1    Jia, S.-F.2    Worth, L.L.3    Zhou, Z.4    Owen-Schaub, L.B.5    Kleinerman, E.S.6
  • 109
    • 9744235167 scopus 로고    scopus 로고
    • Increased Fas expression reduces the metastatic potential of human osteosarcoma cells
    • DOI 10.1158/1078-0432.CCR-04-0353
    • Lafleur E. A., Koshkina N. V., Stewart J., Jia S. F., Worth L. L., Duan X., Kleinerman E. S., Increased Fas expression reduces the metastatic potential of human osteosarcoma cells Clinical Cancer Research 2004 10 23 8114 8119 (Pubitemid 39587553)
    • (2004) Clinical Cancer Research , vol.10 , Issue.23 , pp. 8114-8119
    • Lafleur, E.A.1    Koshkina, N.V.2    Stewart, J.3    Jia, S.-F.4    Worth, L.L.5    Duan, X.6    Kleinerman, E.S.7
  • 110
    • 29944442360 scopus 로고    scopus 로고
    • Interleukin-12 up-regulates Fas expression in human osteosarcoma and Ewing's sarcoma cells by enhancing its promoter activity
    • DOI 10.1158/1541-7786.MCR-05-0092
    • Zhou Z., Lafleur E. A., Koshkina N. V., Worth L. L., Lester M. S., Kleinerman E. S., Interleukin-12 up-regulates Fas expression in human osteosarcoma and Ewing's sarcoma cells by enhancing its promoter activity Molecular Cancer Research 2005 3 12 685 691 (Pubitemid 43042998)
    • (2005) Molecular Cancer Research , vol.3 , Issue.12 , pp. 685-691
    • Zhou, Z.1    Lafleur, E.A.2    Koshkina, N.V.3    Worth, L.L.4    Lester, M.S.5    Kleinerman, E.S.6
  • 111
    • 33644838080 scopus 로고    scopus 로고
    • Intranasal interleukin-12 gene therapy enhanced the activity of ifosfamide against osteosarcoma lung metastases
    • DOI 10.1002/cncr.21744
    • Duan X., Jia S. F., Koshkina N., Kleinerman E. S., Intranasal interleukin-12 gene therapy enhanced the activity of ifosfamide against osteosarcoma lung metastases Cancer 2006 106 6 1382 1388 (Pubitemid 43363918)
    • (2006) Cancer , vol.106 , Issue.6 , pp. 1382-1388
    • Duan, X.1    Jia, S.-F.2    Koshkina, N.3    Kleinerman, E.S.4
  • 112
    • 40749143460 scopus 로고    scopus 로고
    • Liposomal muramyl tripeptide phosphatidyl ethanolamine: A safe and effective agent against osteosarcoma pulmonary metastases
    • DOI 10.1586/14737140.8.2.151
    • Mori K., Ando K., Heymann D., Liposomal muramyl tripeptide phosphatidyl ethanolamine: a safe and effective agent against osteosarcoma pulmonary metastases Expert Review of Anticancer Therapy 2008 8 2 151 159 (Pubitemid 351385905)
    • (2008) Expert Review of Anticancer Therapy , vol.8 , Issue.2 , pp. 151-159
    • Mori, K.1    Ando, K.2    Heymann, D.3
  • 114
    • 0033924248 scopus 로고    scopus 로고
    • Interleukin 18 - Interferon γ inducing factor - A novel player in tumour immunotherapy?
    • DOI 10.1006/cyto.1999.0563
    • Golab J., Interleukin 18Interferon inducing factora novel player in tumour immunotherapy? Cytokine 2000 12 4 332 338 (Pubitemid 30449823)
    • (2000) Cytokine , vol.12 , Issue.4 , pp. 332-338
    • Golab, J.1
  • 115
    • 0032786495 scopus 로고    scopus 로고
    • Interleukin-18 acts as an angiogenesis and tumor suppressor
    • Cao R., Farnebo J., Kurimoto M., Cao Y., Interleukin-18 acts as an angiogenesis and tumor suppressor The FASEB Journal 1999 13 15 2195 2202
    • (1999) The FASEB Journal , vol.13 , Issue.15 , pp. 2195-2202
    • Cao, R.1    Farnebo, J.2    Kurimoto, M.3    Cao, Y.4
  • 116
    • 0030728769 scopus 로고    scopus 로고
    • Interleukin 18 enhances Fas ligand expression and induces apoptosis in Fas-expressing human myelomonocytic KG-1 cells
    • Ohtsuki T., Micallef M. J., Kohno K., Tanimoto T., Ikeda M., Kurimoto M., Interleukin 18 enhances Fas ligand expression and induces apoptosis in Fas-expressing human myelomonocytic KG-1 cells Anticancer Research 1997 17 5 3253 3258 (Pubitemid 27522278)
    • (1997) Anticancer Research , vol.17 , Issue.5 A , pp. 3253-3258
    • Ohtsuki, T.1    Micallef, M.J.2    Kohno, K.3    Tanimoto, T.4    Ikeda, M.5    Kurimoto, M.6
  • 118
    • 69749102736 scopus 로고    scopus 로고
    • Immunotherapy with interleukin-18 in combination with preoperative chemotherapy with ifosfamide effectively inhibits postoperative progression of pulmonary metastases in a mouse osteosarcoma model
    • Yamada N., Hata M., Ohyama H., Yamanegi K., Kogoe N., Nakasho K., Futani H., Okamura H., Terada N., Immunotherapy with interleukin-18 in combination with preoperative chemotherapy with ifosfamide effectively inhibits postoperative progression of pulmonary metastases in a mouse osteosarcoma model Tumor Biology 2009 30 4 176 184
    • (2009) Tumor Biology , vol.30 , Issue.4 , pp. 176-184
    • Yamada, N.1    Hata, M.2    Ohyama, H.3    Yamanegi, K.4    Kogoe, N.5    Nakasho, K.6    Futani, H.7    Okamura, H.8    Terada, N.9
  • 119
    • 0028927484 scopus 로고
    • Suppression of ICE and apoptosis in mammary epithelial cells by extracellular matrix
    • Boudreau N., Sympson C. J., Werb Z., Bissell M. J., Suppression of ICE and apoptosis in mammary epithelial cells by extracellular matrix Science 1995 267 5199 891 893
    • (1995) Science , vol.267 , Issue.5199 , pp. 891-893
    • Boudreau, N.1    Sympson, C.J.2    Werb, Z.3    Bissell, M.J.4
  • 120
    • 0034913123 scopus 로고    scopus 로고
    • Apoptotic signaling during initiation of detachment-induced apoptosis ("anoikis") of primary human intestinal epithelial cells
    • Grossmann J., Walther K., Artinger M., Kiessling S., Schlmerich J., Apoptotic signaling during initiation of detachment-induced apoptosis ("anoikis") of primary human intestinal epithelial cells Cell Growth and Differentiation 2001 12 3 147 155 (Pubitemid 32678000)
    • (2001) Cell Growth and Differentiation , vol.12 , Issue.3 , pp. 147-155
    • Grossmann, J.1    Walther, K.2    Artinger, M.3    Kiessling, S.4    Scholmerich, J.5
  • 122
    • 0141483222 scopus 로고    scopus 로고
    • Acquisition of anoikis resistance in human osteosarcoma cells
    • DOI 10.1016/S0959-8049(03)00575-6
    • Diaz-Montero C. M., McIntyre B. W., Acquisition of anoikis resistance in human osteosarcoma cells European Journal of Cancer 2003 39 16 2395 2402 (Pubitemid 37214865)
    • (2003) European Journal of Cancer , vol.39 , Issue.16 , pp. 2395-2402
    • Diaz-Montero, C.M.1    McIntyre, B.W.2
  • 123
    • 4344687434 scopus 로고    scopus 로고
    • Anoikis: Cancer and the homeless cell
    • Liotta L. A., Kohn E., Anoikis: cancer and the homeless cell Nature 2004 430 7003 973 974
    • (2004) Nature , vol.430 , Issue.7003 , pp. 973-974
    • Liotta, L.A.1    Kohn, E.2
  • 124
    • 33745684527 scopus 로고    scopus 로고
    • Metastasis: A question of life or death
    • Mehlen P., Puisieux A., Metastasis: a question of life or death Nature Reviews Cancer 2006 6 6 449 458
    • (2006) Nature Reviews Cancer , vol.6 , Issue.6 , pp. 449-458
    • Mehlen, P.1    Puisieux, A.2
  • 125
    • 0035977147 scopus 로고    scopus 로고
    • A signaling adapter function for α6β4 integrin in the control of HGF-dependent invasive growth
    • DOI 10.1016/S0092-8674(01)00567-0
    • Trusolino L., Bertotti A., Comoglio P. M., A signaling adapter function for 6 4 integrin in the control of HGF-dependent invasive growth Cell 2001 107 5 643 654 (Pubitemid 34014865)
    • (2001) Cell , vol.107 , Issue.5 , pp. 643-654
    • Trusolino, L.1    Bertotti, A.2    Comoglio, P.M.3
  • 126
    • 7944224012 scopus 로고    scopus 로고
    • Integrin β4 signaling promotes tumor angiogenesis
    • DOI 10.1016/j.ccr.2004.09.029, PII S1535610804002995
    • Nikolopoulos S. N., Blaikie P., Yoshioka T., Guo W., Giancotti F. G., Integrin 4 signaling promotes tumor angiogenesis Cancer Cell 2004 6 5 471 483 (Pubitemid 39469983)
    • (2004) Cancer Cell , vol.6 , Issue.5 , pp. 471-483
    • Nikolopoulos, S.N.1    Blaikie, P.2    Yoshioka, T.3    Guo, W.4    Giancotti, F.G.5
  • 127
    • 33746764457 scopus 로고    scopus 로고
    • β4 Integrin Amplifies ErbB2 Signaling to Promote Mammary Tumorigenesis
    • DOI 10.1016/j.cell.2006.05.047, PII S009286740600907X
    • Guo W., Pylayeva Y., Pepe A., Yoshioka T., Muller W. J., Inghirami G., Giancotti F. G., 4 integrin amplifies ErbB2 signaling to promote mammary tumorigenesis Cell 2006 126 3 489 502 (Pubitemid 44163602)
    • (2006) Cell , vol.126 , Issue.3 , pp. 489-502
    • Guo, W.1    Pylayeva, Y.2    Pepe, A.3    Yoshioka, T.4    Muller, W.J.5    Inghirami, G.6    Giancotti, F.G.7
  • 129
    • 55949128465 scopus 로고    scopus 로고
    • Anoikis: A necessary death program for anchorage-dependent cells
    • Chiarugi P., Giannoni E., Anoikis: a necessary death program for anchorage-dependent cells Biochemical Pharmacology 2008 76 11 1352 1364
    • (2008) Biochemical Pharmacology , vol.76 , Issue.11 , pp. 1352-1364
    • Chiarugi, P.1    Giannoni, E.2
  • 130
    • 3543077594 scopus 로고    scopus 로고
    • Switch from αvβ5 to αvβ6 integrin expression protects squamous cell carcinomas from anoikis
    • DOI 10.1083/jcb.200312074
    • Janes S. M., Watt F. M., Switch from v 5 to v 6 integrin expression protects squamous cell carcinomas from anoikis Journal of Cell Biology 2004 166 3 419 431 (Pubitemid 39031244)
    • (2004) Journal of Cell Biology , vol.166 , Issue.3 , pp. 419-431
    • Janes, S.M.1    Watt, F.M.2
  • 131
    • 29144534595 scopus 로고    scopus 로고
    • Structure of caveolae
    • DOI 10.1016/j.bbamcr.2005.08.008, PII S0167488905001862, Lipid Refts: From Model Membranes to Cells
    • Stan R. V., Structure of caveolae Biochimica et Biophysica Acta 2005 1746 3 334 348 (Pubitemid 41815027)
    • (2005) Biochimica et Biophysica Acta - Molecular Cell Research , vol.1746 , Issue.3 , pp. 334-348
    • Stan, R.V.1
  • 135
    • 0033972059 scopus 로고    scopus 로고
    • Intravascular origin of metastasis from the proliferation of endothelium-attached tumor cells: A new model for metastasis
    • DOI 10.1038/71429
    • Al-Mehdi A. B., Tozawa K., Fisher A. B., Shientag L., Lee A., Muschel R. J., Intravascular origin of metastasis from the proliferation of endothelium-attached tumor cells: a new model for metastasis Nature Medicine 2000 6 1 100 102 (Pubitemid 30048535)
    • (2000) Nature Medicine , vol.6 , Issue.1 , pp. 100-102
    • Al-Mehdi, A.B.1    Tozawa, K.2    Fisher, A.B.3    Shientag, L.4    Lee, A.5    Muschel, R.J.6
  • 137
    • 79960316237 scopus 로고    scopus 로고
    • Relationships between levels of CXCR4 and VEGF and blood-borne metastasis and survival in patients with osteosarcoma
    • Lin F., Zheng S.-E., Shen Z., Tang L.-N., Chen P., Sun Y.-J., Zhao H., Yao Y., Relationships between levels of CXCR4 and VEGF and blood-borne metastasis and survival in patients with osteosarcoma Medical Oncology 2011 28 2 649 653
    • (2011) Medical Oncology , vol.28 , Issue.2 , pp. 649-653
    • Lin, F.1    Zheng, S.-E.2    Shen, Z.3    Tang, L.-N.4    Chen, P.5    Sun, Y.-J.6    Zhao, H.7    Yao, Y.8
  • 138
    • 17644420691 scopus 로고    scopus 로고
    • Messenger RNA expression levels of CXCR4 correlate with metastatic behavior and outcome in patients with osteosarcoma
    • DOI 10.1158/1078-0432.CCR-04-1089
    • Laverdiere C., Hoang B. H., Yang R., Sowers R., Qin J., Meyers P. A., Huvos A. G., Healey J. H., Gorlick R., Messenger RNA expression levels of CXCR4 correlate with metastatic behavior and outcome in patients with osteosarcoma Clinical Cancer Research 2005 11 7 2561 2567 (Pubitemid 40569454)
    • (2005) Clinical Cancer Research , vol.11 , Issue.7 , pp. 2561-2567
    • Laverdiere, C.1    Hoang, B.H.2    Yang, R.3    Sowers, R.4    Qin, J.5    Meyers, P.A.6    Huvos, A.G.7    Healey, J.H.8    Gorlick, R.9
  • 139
    • 69249247048 scopus 로고    scopus 로고
    • Stromal cell-derived factor-1/CXCR4 enhanced motility of human osteosarcoma cells involves MEK1/2, ERK and NF- B-dependent pathways
    • Huang C. Y., Lee C. Y., Chen M. Y., Yang W. H., Chen Y. H., Chang C. H., Hsu H. C., Fong Y. C., Tang C. H., Stromal cell-derived factor-1/CXCR4 enhanced motility of human osteosarcoma cells involves MEK1/2, ERK and NF- B-dependent pathways Journal of Cellular Physiology 2009 221 1 204 212
    • (2009) Journal of Cellular Physiology , vol.221 , Issue.1 , pp. 204-212
    • Huang, C.Y.1    Lee, C.Y.2    Chen, M.Y.3    Yang, W.H.4    Chen, Y.H.5    Chang, C.H.6    Hsu, H.C.7    Fong, Y.C.8    Tang, C.H.9
  • 140
    • 0035856010 scopus 로고    scopus 로고
    • Chemokines and the molecular basis of cancer metastasis
    • Murphy P. M., Chemokines and the molecular basis of cancer metastasis The New England Journal of Medicine 2001 345 11 833 835
    • (2001) The New England Journal of Medicine , vol.345 , Issue.11 , pp. 833-835
    • Murphy, P.M.1
  • 147
    • 0034651010 scopus 로고    scopus 로고
    • The chemokine receptor CXCR3 is expressed in a subset of B-cell lymphomas and is a marker of B-cell chronic lymphocytic leukemia
    • Jones D., Benjamin R. J., Shahsafaei A., Dorfman D. M., The chemokine receptor CXCR3 is expressed in a subset of B-cell lymphomas and is a marker of B-cell chronic lymphocytic leukemia Blood 2000 95 2 627 632 (Pubitemid 30041679)
    • (2000) Blood , vol.95 , Issue.2 , pp. 627-632
    • Jones, D.1    Benjamin, R.J.2    Shahsafaei, A.3    Dorfman, D.M.4
  • 148
    • 1842663068 scopus 로고    scopus 로고
    • The expression of the chemokine receptor CXCR3 and its ligand, CXCL10, in human breast adenocarcinoma cell lines
    • DOI 10.1016/j.imlet.2003.10.020, PII S0165247803003158
    • Goldberg-Bittman L., Neumark E., Sagi-Assif O., Azenshtein E., Meshel T., Witz I. P., Ben-Baruch A., The expression of the chemokine receptor CXCR3 and its ligand, CXCL10, in human breast adenocarcinoma cell lines Immunology Letters 2004 92 1-2 171 178 (Pubitemid 38470065)
    • (2004) Immunology Letters , vol.92 , Issue.1-2 , pp. 171-178
    • Goldberg-Bittman, L.1    Neumark, E.2    Sagi-Assif, O.3    Azenshtein, E.4    Meshel, T.5    Witz, I.P.6    Ben-Baruch, A.7
  • 149
    • 0032940071 scopus 로고    scopus 로고
    • ERM proteins in cell adhesion and membrane dynamics
    • DOI 10.1016/S0962-8924(99)01544-5, PII S0962892499015445
    • Mangeat P., Roy C., Martin M., ERM proteins in cell adhesion and membrane dynamics Trends in Cell Biology 1999 9 5 187 192 (Pubitemid 29192986)
    • (1999) Trends in Cell Biology , vol.9 , Issue.5 , pp. 187-192
    • Mangeat, P.1    Roy, C.2    Martin, M.3
  • 150
    • 0029795488 scopus 로고    scopus 로고
    • Regulation mechanism of ERM (ezrin/radixin/moesin) protein/plasma membrane association: Possible involvement of phosphatidylinositol turnover and rho-dependent signaling pathway
    • DOI 10.1083/jcb.135.1.37
    • Hirao M., Sato N., Kondo T., Yonemura S., Monden M., Sasaki T., Takai Y., Tsukita S., Tsukita S., Regulation mechanism of ERM (ezrin/radixin/moesin) protein/plasma membrane association: possible involvement of phosphatidylinositol turnover and rho-dependent signaling pathway Journal of Cell Biology 1996 135 1 37 51 (Pubitemid 26337735)
    • (1996) Journal of Cell Biology , vol.135 , Issue.1 , pp. 37-51
    • Hirao, M.1    Sato, N.2    Kondo, T.3    Yonemura, S.4    Monden, M.5    Sasaki, T.6    Takai, Y.7    Tsukita, S.8    Tsukita, S.9
  • 151
    • 0033594950 scopus 로고    scopus 로고
    • Ezrin, a plasma membrane-microfilament linker, signals cell survival through the phosphatidylinositol 3-kinase/Akt pathway
    • DOI 10.1073/pnas.96.13.7300
    • Gautreau A., Poullet P., Louvard D., Arpin M., Ezrin, a plasma membrane-microfilament linker, signals cell survival through the phosphatidylinositol 3-kinase/Akt pathway Proceedings of the National Academy of Sciences of the United States of America 1999 96 13 7300 7305 (Pubitemid 29299656)
    • (1999) Proceedings of the National Academy of Sciences of the United States of America , vol.96 , Issue.13 , pp. 7300-7305
    • Gautreau, A.1    Poullet, P.2    Louvard, D.3    Arpin, M.4
  • 152
    • 2342477964 scopus 로고    scopus 로고
    • Ezrin, a key component in tumor metastasis
    • DOI 10.1016/j.molmed.2004.03.001, PII S1471491404000747
    • Hunter K. W., Ezrin, a key component in tumor metastasis Trends in Molecular Medicine 2004 10 5 201 204 (Pubitemid 38581790)
    • (2004) Trends in Molecular Medicine , vol.10 , Issue.5 , pp. 201-204
    • Hunter, K.W.1
  • 153
    • 16444370230 scopus 로고    scopus 로고
    • Ezrin in primary cutaneous melanoma
    • DOI 10.1038/modpathol.3800300
    • Ilmonen S., Vaheri A., Asko-Seljavaara S., Carpen O., Ezrin in primary cutaneous melanoma Modern Pathology 2005 18 4 503 510 (Pubitemid 40478113)
    • (2005) Modern Pathology , vol.18 , Issue.4 , pp. 503-510
    • Ilmonen, S.1    Vaheri, A.2    Asko-Seljavaara, S.3    Carpen, O.4
  • 154
    • 24344464300 scopus 로고    scopus 로고
    • Prognostic impact of immunohistochemical expression of ezrin in highly malignant soft tissue sarcomas
    • DOI 10.1158/1078-0432.CCR-05-0548
    • Weng W. H., hlén J., strm K., Lui W. O., Larsson C., Prognostic impact of immunohistochemical expression of ezrin in highly malignant soft tissue sarcomas Clinical Cancer Research 2005 11 17 6198 6204 (Pubitemid 41262948)
    • (2005) Clinical Cancer Research , vol.11 , Issue.17 , pp. 6198-6204
    • Weng, W.-H.1    Ahlen, J.2    Astrom, K.3    Lui, W.-O.4    Larsson, C.5
  • 156
    • 60149109981 scopus 로고    scopus 로고
    • The actin-cytoskeleton linker protein ezrin is regulated during osteosarcoma metastasis by PKC
    • Ren L., Hong S. H., Cassavaugh J., Osborne T., Chou A. J., Gorlick R., Hewitt S. M., Khanna C., The actin-cytoskeleton linker protein ezrin is regulated during osteosarcoma metastasis by PKC Oncogene 2009 28 6 792 802
    • (2009) Oncogene , vol.28 , Issue.6 , pp. 792-802
    • Ren, L.1    Hong, S.H.2    Cassavaugh, J.3    Osborne, T.4    Chou, A.J.5    Gorlick, R.6    Hewitt, S.M.7    Khanna, C.8
  • 162
    • 0032926738 scopus 로고    scopus 로고
    • Serum free insulin-like growth factor I (IGF-I), total IGF-I, and IGF- binding protein-3 concentrations in normal children and children with growth hormone deficiency
    • DOI 10.1210/jc.84.1.82
    • Kawai N., Kanzaki S., Takano-Watou S., Tada C., Yamanaka Y., Miyata T., Oka M., Seino Y., Serum free insulin-like growth factor I (IGF-I), total IGF-I, and IGF- binding protein-3 concentrations in normal children and children with growth hormone deficiency Journal of Clinical Endocrinology and Metabolism 1999 84 1 82 89 (Pubitemid 29036684)
    • (1999) Journal of Clinical Endocrinology and Metabolism , vol.84 , Issue.1 , pp. 82-89
    • Kawai, N.1    Kanzaki, S.2    Takano-Watou, S.3    Tada, C.4    Yamanaka, Y.5    Miyata, T.6    Oka, M.7    Seino, Y.8
  • 163
    • 0003482410 scopus 로고    scopus 로고
    • Insulin-like growth factor-I inhibits the progression of human U-2 OS osteosarcoma cells towards programmed cell death through interaction with the IGF-I receptor
    • Herzlieb N., Gallaher B. W., Berthold A., Hille R., Kiess W., Insulin-like growth factor-I inhibits the progression of human U-2 OS osteosarcoma cells towards programmed cell death through interaction with the IGF-I receptor Cellular and Molecular Biology 2000 46 1 71 77
    • (2000) Cellular and Molecular Biology , vol.46 , Issue.1 , pp. 71-77
    • Herzlieb, N.1    Gallaher, B.W.2    Berthold, A.3    Hille, R.4    Kiess, W.5
  • 164
    • 0028332784 scopus 로고
    • Human osteosarcoma cell lines are dependent on insulin-like growth factor I for in vitro growth
    • Kappel C. C., Velez-Yanguas M. C., Hirschfeld S., Helman L. J., Human osteosarcoma cell lines are dependent on insulin-like growth factor I for in vitro growth Cancer Research 1994 54 10 2803 2807 (Pubitemid 24173778)
    • (1994) Cancer Research , vol.54 , Issue.10 , pp. 2803-2807
    • Kappel, C.C.1    Velez-Yanguas, M.C.2    Hirschfeld, S.3    Helman, L.J.4
  • 167
    • 0035992429 scopus 로고    scopus 로고
    • A randomized controlled trial of octreotide pamoate long-acting release and carboplatin versus carboplatin alone in dogs with naturally occurring osteosarcoma: Evaluation of insulin-like growth factor suppression and chemotherapy
    • Khanna C., Prehn J., Hayden D., Cassaday R. D., Caylor J., Jacob S., Bose S. M., Hong S. H., Hewitt S. M., Helman L. J., A randomized controlled trial of octreotide pamoate long-acting release and carboplatin versus carboplatin alone in dogs with naturally occurring osteosarcoma: evaluation of insulin-like growth factor suppression and chemotherapy Clinical Cancer Research 2002 8 7 2406 2412 (Pubitemid 34753616)
    • (2002) Clinical Cancer Research , vol.8 , Issue.7 , pp. 2406-2412
    • Khanna, C.1    Prehn, J.2    Hayden, D.3    Cassaday, R.D.4    Caylor, J.5    Jacob, S.6    Bose, S.M.7    Hong, S.-H.8    Hewitt, S.M.9    Helman, L.J.10
  • 168
    • 67349165458 scopus 로고    scopus 로고
    • Lentivirus-mediated RNAi knockdown of insulin-like growth factor-1 receptor inhibits growth, reduces invasion, and enhances radiosensitivity in human osteosarcoma cells
    • Wang Y. H., Wang Z. X., Qiu Y., Xiong J., Chen Y. X., Miao D. S., De W., Lentivirus-mediated RNAi knockdown of insulin-like growth factor-1 receptor inhibits growth, reduces invasion, and enhances radiosensitivity in human osteosarcoma cells Molecular and Cellular Biochemistry 2009 327 1-2 257 266
    • (2009) Molecular and Cellular Biochemistry , vol.327 , Issue.12 , pp. 257-266
    • Wang, Y.H.1    Wang, Z.X.2    Qiu, Y.3    Xiong, J.4    Chen, Y.X.5    Miao, D.S.6    De, W.7
  • 169
    • 77955013854 scopus 로고    scopus 로고
    • Lentivirus-mediated shRNA targeting insulin-like growth factor-1 receptor (IGF-1R) enhances chemosensitivity of osteosarcoma cells in vitro and in vivo
    • Wang Y. H., Xiong J., Wang S. F., Yu Y., Wang B., Chen Y. X., Shi H. F., Qiu Y., Lentivirus-mediated shRNA targeting insulin-like growth factor-1 receptor (IGF-1R) enhances chemosensitivity of osteosarcoma cells in vitro and in vivo Molecular and Cellular Biochemistry 2010 341 1-2 225 233
    • (2010) Molecular and Cellular Biochemistry , vol.341 , Issue.12 , pp. 225-233
    • Wang, Y.H.1    Xiong, J.2    Wang, S.F.3    Yu, Y.4    Wang, B.5    Chen, Y.X.6    Shi, H.F.7    Qiu, Y.8
  • 171
    • 77953256426 scopus 로고    scopus 로고
    • R1507, a fully human monoclonal antibody targeting IGF-1R, is effective alone and in combination with rapamycin in inhibiting growth of osteosarcoma xenografts
    • Kolb E. A., Kamara D., Zhang W., Lin J., Hingorani P., Baker L., Houghton P., Gorlick R., R1507, a fully human monoclonal antibody targeting IGF-1R, is effective alone and in combination with rapamycin in inhibiting growth of osteosarcoma xenografts Pediatric Blood and Cancer 2010 55 1 67 75
    • (2010) Pediatric Blood and Cancer , vol.55 , Issue.1 , pp. 67-75
    • Kolb, E.A.1    Kamara, D.2    Zhang, W.3    Lin, J.4    Hingorani, P.5    Baker, L.6    Houghton, P.7    Gorlick, R.8
  • 172
    • 84860389568 scopus 로고    scopus 로고
    • Increased expression of insulin-like growth factor-1 receptor is correlated with tumor metastasis and prognosis in patients with osteosarcoma
    • Wang Y. H., Han X. D., Qiu Y., Increased expression of insulin-like growth factor-1 receptor is correlated with tumor metastasis and prognosis in patients with osteosarcoma Journal of Surgical Oncology 2012 105 3 235 243
    • (2012) Journal of Surgical Oncology , vol.105 , Issue.3 , pp. 235-243
    • Wang, Y.H.1    Han, X.D.2    Qiu, Y.3
  • 173
    • 2942538264 scopus 로고    scopus 로고
    • Dissecting the metastatic cascade
    • Pantel K., Brakenhoff R. H., Dissecting the metastatic cascade Nature Reviews Cancer 2004 4 6 448 456 (Pubitemid 38745530)
    • (2004) Nature Reviews Cancer , vol.4 , Issue.6 , pp. 448-456
    • Pantel, K.1    Brakenhoff, R.H.2
  • 174
    • 35548936833 scopus 로고    scopus 로고
    • Models, mechanisms and clinical evidence for cancer dormancy
    • DOI 10.1038/nrc2256, PII NRC2256
    • Aguirre-Ghiso J. A., Models, mechanisms and clinical evidence for cancer dormancy Nature Reviews Cancer 2007 7 11 834 846 (Pubitemid 350006258)
    • (2007) Nature Reviews Cancer , vol.7 , Issue.11 , pp. 834-846
    • Aguirre-Ghiso, J.A.1
  • 176
    • 0028951043 scopus 로고
    • Dormancy of micrometastases: Balanced proliferation and apoptosis in the presence of angiogenesis suppression
    • Holmgren L., O'Reilly M. S., Folkman J., Dormancy of micrometastases: balanced proliferation and apoptosis in the presence of angiogenesis suppression Nature Medicine 1995 1 2 149 153
    • (1995) Nature Medicine , vol.1 , Issue.2 , pp. 149-153
    • Holmgren, L.1    O'Reilly, M.S.2    Folkman, J.3
  • 177
    • 52049116094 scopus 로고    scopus 로고
    • Cancer micrometastasis and tumour dormancy
    • Wikman H., Vessella R., Pantel K., Cancer micrometastasis and tumour dormancy APMIS 2008 116 7-8 754 770
    • (2008) APMIS , vol.116 , Issue.78 , pp. 754-770
    • Wikman, H.1    Vessella, R.2    Pantel, K.3
  • 179
    • 0032031748 scopus 로고    scopus 로고
    • Expression of angiostatin cDNA in a murine fibrosarcoma suppresses primary tumor growth and produces long-term dormancy of metastases
    • Cao Y., O'Reilly M. S., Marshall B., Flynn E., Ji R. W., Folkman J., Expression of angiostatin cDNA in a murine fibrosarcoma suppresses primary tumor growth and produces long-term dormancy of metastases Journal of Clinical Investigation 1998 101 5 1055 1063 (Pubitemid 28125284)
    • (1998) Journal of Clinical Investigation , vol.101 , Issue.5 , pp. 1055-1063
    • Cao, Y.1    O'Reilly, M.S.2    Marshall, B.3    Flynn, E.4    Ji, R.-W.5    Folkman, J.6
  • 180
    • 52049091826 scopus 로고    scopus 로고
    • Cellular interactions in the vascular niche: Implications in the regulation of tumor dormancy
    • Favaro E., Amadori A., Indraccolo S., Cellular interactions in the vascular niche: implications in the regulation of tumor dormancy APMIS 2008 116 7-8 648 659
    • (2008) APMIS , vol.116 , Issue.78 , pp. 648-659
    • Favaro, E.1    Amadori, A.2    Indraccolo, S.3
  • 181
    • 77950594400 scopus 로고    scopus 로고
    • Extracellular matrix: A gatekeeper in the transition from dormancy to metastatic growth
    • Barkan D., Green J. E., Chambers A. F., Extracellular matrix: a gatekeeper in the transition from dormancy to metastatic growth European Journal of Cancer 2010 46 7 1181 1188
    • (2010) European Journal of Cancer , vol.46 , Issue.7 , pp. 1181-1188
    • Barkan, D.1    Green, J.E.2    Chambers, A.F.3
  • 182
    • 36849010167 scopus 로고    scopus 로고
    • Adaptive immunity maintains occult cancer in an equilibrium state
    • DOI 10.1038/nature06309, PII NATURE06309
    • Koebel C. M., Vermi W., Swann J. B., Zerafa N., Rodig S. J., Old L. J., Smyth M. J., Schreiber R. D., Adaptive immunity maintains occult cancer in an equilibrium state Nature 2007 450 7171 903 907 (Pubitemid 350231320)
    • (2007) Nature , vol.450 , Issue.7171 , pp. 903-907
    • Koebel, C.M.1    Vermi, W.2    Swann, J.B.3    Zerafa, N.4    Rodig, S.J.5    Old, L.J.6    Smyth, M.J.7    Schreiber, R.D.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.