Mouse endostatin inhibits the formation of lung and liver metastases

Cancer Research

Volumn 59, Issue 24, 1999, Pages 6251-6256

  Yoon, Sam S ^a   Eto, Hiroshi ^a,b   Lin, Cheng Mao ^a   Nakamura, Hideo ^a   Pawlik, Timothy M ^a   Song, Sun U ^a   Tanabe, Kenneth K ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b KOBE UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOGENESIS INHIBITOR; ENDOSTATIN; POLYHISTIDINE;

ANGIOGENESIS; ANIMAL CELL; ARTICLE; CANCER GROWTH; CARCINOGENESIS; CELL PROLIFERATION; CONTROLLED STUDY; GENE CONTROL; GENE EXPRESSION; GENE TARGETING; LIVER METASTASIS; LUNG METASTASIS; MOUSE; NONHUMAN; ONCOGENE C MYC; PRIORITY JOURNAL; PROTEIN SECRETION;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL DIVISION; COLLAGEN; ENDOSTATINS; ENDOTHELIUM, VASCULAR; HUMANS; LIVER NEOPLASMS; LUNG NEOPLASMS; MICE; MICE, INBRED BALB C; MICE, NUDE; NEOPLASM METASTASIS; PEPTIDE FRAGMENTS; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0033572414     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. Paget, S. The distribution of secondary growths in cancer in the breast. Lancet, 1: 571-573, 1889.
2. Fidler, I. J. Modulation of the organ microenvironment for treatment of cancer metastasis. J. Natl. Cancer Inst., 87: 1588-1592, 1995.
3. Hanahan, D., and Folkman, J. Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell, 86: 353-364, 1996.
4. Singh, R. K., Bucana, C. D., Gutman, M. R., Fan, D., Wilson, M. R., and Fidler, I. J. Organ site-dependent expression of basic fibroblast growth factor in human renal cell carcinoma cells. Am. J. Pathol., 145: 365-376, 1994.
5. Fukumura, D., Yuan, F., Monsky, W. L., Chen, Y., and Jain, R. K. Effect of host microenvironment on the microcirculation of human colon adenocarcinoma. Am. J. Pathol., 151: 679-688, 1997.
6. Terayama, N., Terada, T., and Nakanuma, Y. A. morphometric and immunohistochemical study on angiogenesis of human metastatic carcinomas of the liver. Hepatology, 24: 816-819, 1996.
7. Junqueira, L. C., Carneiro, J., and Kelley, R. O. Basic Histology, Ed. 6, p. 514, Norwalk: Appleton & Lange, 1989.
8. O'Reilly, M. S., Boehm, T., Shing, Y., Fukai, N., Vasios, G., Lane, W. S., Flynn, E., Birkhead, J. R., Olsen, B. R., and Folkman, J. Endostatin: an endogenous inhibitor of angiogenesis and tumor growth. Cell, 88: 277-285, 1997.
9. Nguyen, J. T., Wu, P., Clouse, M. E., Hlatky, L., and Terwilliger, E. F. Adeno-associated virus-mediated delivery of anliangiogenic factors as an antitumor strategy. Cancer Res., 58: 5673-5677, 1998.
10. Dhanabal, M., Ramchandran, R., Volk, R., Stillman, I. E., Lombardo, M., Iruela-Arispe, M. L., Simons, M., and Sukhatme, V. P. Endostatin: yeast production, mutants, and antitumor effect in renal cell carcinoma. Cancer Res., 59: 189-197, 1999.
11. Blezinger, P., Wang, J., Gondo, M., Quezada, A., Mehrens, D., French, M., Singhal, A., Sullivan, S., Rolland, A., Ralston, R., and Min, W. Systemic inhibition of tumor growth and tumor metastases by intramuscular administration of the endostatin gene. Nat. Biotech., 17: 343-348, 1999.
12. Sim, B. K. L., Fogler, W. E., Zhou, X. H., Liang, H., Madsen, J. W., O'Reilly, M. S., Panigrahy, D., and Fortier, A. H. Potent inhibition of experimental metastases and primary tumors by recombinant human endostatin that is suitable for human use. Proc. Am. Assoc. Cancer Res., 40: 620-621, 1999.
13. Murphy, G. P., and Hrushesky, W. J. A murine renal cell carcinoma. J. Natl. Cancer Inst., 50: 1013-1025, 1973.
14. Yoon, S. S., Carroll, N. M., Chiocca, E. A., and Tanabe, K. K. Cancer gene therapy using a replication-competent herpes simplex virus type 1 vector. Ann. Surg., 228: 366-374, 1998.
15. Chakrabarty, A., Hillman, G. G., Maughan, R. L., Visscher, D. W,. Ali, E., Pontes, J. E., and Haas, G. P. Influence of tumor site on the therapy of murine kidney cancer. Anticancer Res., 14: 373-378, 1994.
16. Zirvi, K. A., Keogh, J. P., Slomiany, A., and Slomiany, B. L. Transglutaminase activity in human colorectal carcinomas of differing metastatic potential. Cancer Lett., 60: 85-92, 1991.
17. Bergers, G., Javaherian, K., Lo, K. M., Folkman, J., and Hanahan, D. Effects of angiogenesis inhibitors on multistage carcinogenesis in mice. Science (Washington DC), 284: 808-812, 1999.
18. Cao, Y., O'Reilly, M. S., Marshall, B., Flynn, E., Ji, R. W., and Folkman, J. Expression of angiostatin cDNA in a murine fibrosarcoma suppresses primary tumor growth and produces long-term dormancy of metastases. J. Clin. Investig., 101: 1055-1063, 1998.
19. Benet, L. Z., Mitchell, J. R., and Sheiner, L. B. Pharmacokinetics: the dynamics of drug absorption, distribution, and elimination. In: A. G, Gilman, T. W. Rall, A. S. Nies, and P. Taylor (eds.), Goodman & Gilman's The Pharmacological Basis of Therapeutics, Ed. 8, pp. 3-32. New York: Pergamon Press, 1990.
20. Knebelmann, B., Dhanabal, M., Ramchandran, R., Waterman, M., Lu, H., and Sukhatme, V. P. Endostatin inhibits VEGF and bFGF induced MAPK activation in endothelial cells. Proc. Am. Assoc. Cancer Res., 40: 414, 1999.