The chemokine receptor CXCR3 is expressed in a subset of B-cell lymphomas and is a marker of B-cell chronic lymphocytic leukemia

Blood

Volumn 95, Issue 2, 2000, Pages 627-632

  Jones, Dan ^a   Benjamin, Richard J ^a   Shahsafaei, Aliakbar ^a   Dorfman, David M ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR;

ARTICLE; B CELL LYMPHOMA; CHEMOTAXIS; CHRONIC LYMPHATIC LEUKEMIA; CONTROLLED STUDY; DISEASE MARKER; HISTOPATHOLOGY; HUMAN; HUMAN CELL; LIGAND BINDING; LYMPHOCYTOMA; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; T LYMPHOCYTE;

EID: 0034651010     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v95.2.627     Document Type: Article

References (43)

1. Sallusto F, Lenig D. Mackay CR, Lanzavecchia A. Flexible programs of chemokine receptor expression on human polarized T helper 1 and 2 lymphocytes. J Exp Med. 1998:187:875-883.
2. Qin S, Rottman JB, Myers P, et al. The chemokine receptors CXCR3 and CCR5 mark subsets of T cells associated with certain inflammatory reactions. J Clin Invest. 1998:101:746-754.
3. Bonecchi R, Bianchi G, Bordignon PP, et al. Differential expression of chemokine receptors and chemotactic responsiveness of type 1 T helper cells (This) andTh2s. J Exp Med. 1998;187:129134.
4. Piali L, Weber C, LaRosa G, et al. The chemokine receptor CXCR3 mediates rapid and shear-resistant adhesion-induction of effector T lymphocytes by the chemokines IP10 and Mig. Eur J Immunol. 1998:28:961-972.
5. Gangur V, Simons FE, Hayglass KT. Human IP-10 selectively promotes dominance of polyclonally activated and environmental antigendriven IFN-gamma over IL-4 responses. FASEB J. 1998:12:705-713.
6. Farber JM. Mig and IP-10: CXC chemokines that target lymphocytes. J Leukoc Biol. 1997;61:246257.
7. Cole KE. Strick ÇA, Paradis TJ, et al. Interferoninducible T cell alpha chemoattractant (I-TAC): a novel non-ELR CXC chemokine with potent activity on activated T cells through selective high affinity binding to CXCR3. J Exp Med. 1998:187: 2009-2021.
8. Sauty A, Dziejman U, Taha RA, et al. The T cellspecific CXC chemokines IP-10, Mig, and I-TAC are expressed by activated human bronchial epithelial cells. J Immunol. 1999:162:3549-3558.
9. Baba M, Imai T, Nishimura M, et al. Identification of CCR6, the specific receptor for a novel lym-phocyte-directed CC chemokine LARC. J Biol Chem. 1997:272:14,893-14,898.
10. Campbell JJ, Bowman EP, Murphy K, et al. 6-Ckine (SLC), a lymphocyte adhesion-triggering chemokine expressed by high endothelium, is an agonist for the MIP-3 receptor CCR7. J Cell Biol. 1998:141:1053-1059.
11. Greaves DR, Wang W, Dairaghi DJ, et al. CCR6, a CC chemokine receptor that interacts with macrophage inflammatory protein Salpha and is highly expressed in human dendritic cells. J Exp Med. 1997:186:837-844.
12. Legier DF, Loetscher M, Roos RS, dark-Lewis I, Baggiolini M, Moser B. B cell-attracting chemokine 1, a human CXC chemokine expressed in lymphoid tissues, selectively attracts B lymphocytes via BLR1/CXCR5. J Exp Med. 1998;187: 655-660.
13. Nagira M, Imai T, Yoshida R, et al. A lymphocytespecific CC chemokine, secondary lymphoid tissue chemokine (SLC), is a highly efficient chemoattractant for B cells and activated T cells. Eur J Immunol. 1998:28:1516-1523.
14. Pachynski RK, Wu SW, Gunn MD, Erle DJ. Secondary lymphoid-tissue chemokine (SLC) stimulates integrin alpha 4 beta 7-mediated adhesion of lymphocytes to mucosal addressin cell adhesion molecule-1 (MAdCAM-1 ) under flow. J Immunol. 1998:161:952-956.
15. Yoshida R, Imai T, Hieshima K, et al. Molecular cloning of a novel human CC chemokine EBI1ligand chemokine that is a specific functional ligand for EBI1, CCR7. J Biol Chem. 1997;272: 13,803-13,809.
16. Harris NL, Jaffe ES, Stein H, et al. A revised European-American classification of lymphoid neoplasms: a proposal from the international lymphoma study group. Blood. 1994:84:1361-1392.
17. Jones D, Reicher COM, Pulford K, Shasafaei A,
18. Dorfman DM. CD30 and CD134/OX40 are expressed in non-overlapping subsets of peripheral T cell lymphoma. Blood. 1999:93:3487-3493.
19. Dorfman DM, Shahsafaei A, Nadler LM, Freeman GJ. The leukocyte semaphorin CD100 is expressed In most T-cell, but few B-cell, nonHodgkin's lymphomas. Am J Pathol. 1998;153: 255-262.
20. Forster R, Emrich T, Kremmer E, Lipp M. Expression of the G-protein-coupled receptor BLR1 defines mature, recirculating B cells and a subset of T-helper memory cells. Blood. 1994:84:830840.
21. Loetscher M, Gerber B, Loetscher P, et al. Chemokine receptor specific for IP10 and Mig: structure, function, and expression in activated T-lymphocytes. J Exp Med. 1996:184:963-969.
22. Loetscher M, Loetscher P, Brass N, Meese E, Moser B. Lymphocyte-specific chemokine receptor CXCR3: regulation, chemokine binding and gene localization. EurJ Immunol. 1998:28:36963705.
23. Trentin L, Agostini C, Facco M, et al. The chemokine receptor CXCR3 is expressed on malignant B cells and mediates chemotaxis. J Clin Invest. 1999:104:115-121.
24. Vicente-Manzanares M, Montoya MC, Mellado M, et al. The chemokine SDF-1 alpha triggers a chemotactic response and induces cell polarization in human B lymphocytes. EurJ Immunol. 1998;28: 2197-2207.
25. D'Apuzzo M, Relink A, Loetscher M, et al. The chemokine SDF-1, stromal cell-derived factor 1, attracts early stage B cell precursors via the chemokine receptorCXCR4. EurJ Immunol. 1997; 27:1788-1793.
26. Fedyk ER, Ryan DH, Ritterman I, Springer TA. Stromal derived factors 1 a and 1 are potent chemoattractants of human B lineage progenitors. J Leuko Biol. 1999; in press.
27. Forster R, Schweigard G, Johann S, et al. Abnormal expression of the B-cell homing chemokine receptor BLR1 during the progression of acquired immunodeficiency syndrome. Blood. 1997;90: 520-525.
28. Forster R, Wolf I, Kaiser E, Lipp M. Selective expression of the murine homologue of the G-protein-coupled receptor BLR1 in B cell differentiation, B cell neoplasia and defined areas of the cerebellum. Cell Mol Biol (Noisy-le-grand). 1994; 40:381-387.
29. DobnerT, Wolf I, Emrich T, Lipp M. Differentiation-specific expression of a novel G proteincoupled receptor from Burkitt's lymphoma. Eur J Immunol. 1992;22:2795-2799.
30. Birkenbach M, Josefsen K, Yalamanchili R, Lenior G, Kieff E. Epstein-Barr virus-induced genes: first lymphocyte-specific G protein-coupled peptide receptors. J Virol. 1993;67:2209-2220.
31. Burgstahler R, Kempkes B, Steube K, Lipp M. Expression of the chemokine receptor BLR2/ EBI1 is specifically transactivated by Epstein-Barr virus. Biochem Biopys Res Commun. 1995;215: 737-743.
32. Ngo VN, Tang HL, Cyster JG. Epstein-Barr virusinduced molecule 1 ligand chemokine is expressed by dendritic cells in lymphoid tissues and strongly attracts naive T cells and activated B cells. JExpMed. 1998:188:181-191.
33. Ma Q, Jones D, Borghesani PR, et al. Impaired B-lymphopoiesis, myelopoiesis, and derailed cerebellar neuron migration in CXCR4- and SDF-1 deficient mice-. Proc Natl Acad Sei USA. 1998;95: 9448-9453.
34. Ma Q, Jones D, Springer TA. The chemokine receptor CXCR4 is required for the retention of B lymphocytic and granulocytic precursors within the bone marrow microenvironment. Immunity. 1999:10:463-471.
35. Bleui CC, Schultze JL, Springer TA. B lymphocyte chemotaxis regulated in association with microanatomic localization, differentiation state, and B cell receptor engagement. J Exp Med. 1998:187: 753-762.
36. Forster R, Mattis AE, Kremmer E, Wolf E, Brem G, Lipp M. A putative chemokine receptor, BLR1, directs B cell migration to defined lymphoid organs and specific anatomic compartments of the spleen. Cell. 1996:87:1037-1047.
37. Gunn MD, Ngo VN, Ansel KM, Ekland EH, Cyster
38. JG, Williams LT. A B-cell-homing chemokine made in lymphoid follicles activates Burkitt's lymphoma receptor-1. Nature. 1998:391:799-803.
39. Reyes E, Prieto A, Carrion F, el a!. Altered pattern of cytokine production by peripheral blood CD2+ cells from B chronic lymphocytic leukemia patients. Am J Hematol. 1998;57:93-100.
40. Sarris AH, Talpaz M, Deisseroth AB, Estrov Z. Human recombinant interferon-inducible pro' tein-10 inhibits the proliferation of normal and acute myelogenous leukemia progenitors. Leukemia. 1996:10:757-765.
41. Saltman D, Bansal NS, Ross FM, Ross JA, Turner G, Guy K. Establishment of a karyotypically normal B-chronic lymphocytic leukemia cell line; evidence of leukemic origin by immunoglobulin gene rearrangement. Leuk Res. 1990; 14:381-387.
42. Zheng CY, Pabello P, Maksymiuk AW, Skinnider LF. Establishment of cell lines derived from chronic lymphocytic leukaemic ceils by transfection with myc and ras. Br J Haematol. 1996;93: 681-683.
43. Marti GE, Zenger V, Brown M, et al. Antigenic expression of B-cell chronic lymphocytic leukemic cell lines. Leuk Lymphoma. 1992:7:497-504.