Dasatinib in imatinib-resistant Philadelphia chromosome-positive leukemias

New England Journal of Medicine

Volumn 354, Issue 24, 2006, Pages 2531-2541

  Talpaz, Moshe ^a   Shah, Neil P ^b   Kantarjian, Hagop ^a   Donato, Nicholas ^a   Nicoll, John ^b   Paquette, Ron ^b   Cortes, Jorge ^a   O'Brien, Susan ^a   Nicaise, Claude ^c   Bleickardt, Eric ^c   Blackwood Chirchir, M Anne ^c   Iyer, Vishwanath ^c   Chen, Tai Tsang ^c   Huang, Fei ^c   Decillis, Arthur P ^c   Sawyers, Charles L ^b,d  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c BRISTOL MYERS SQUIBB   (United States)

^d HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BCR ABL PROTEIN; DASATINIB; IMATINIB; PROTEIN TYROSINE KINASE INHIBITOR; UNCLASSIFIED DRUG;

ACUTE LYMPHOBLASTIC LEUKEMIA; ADULT; AGED; ARTICLE; BONE MARROW SUPPRESSION; CHRONIC MYELOID LEUKEMIA; CONTROLLED STUDY; DRUG TOLERANCE; FEMALE; GENE MUTATION; GENOTYPE; HUMAN; IN VITRO STUDY; MAJOR CLINICAL STUDY; MALE; PH; PHILADELPHIA 1 CHROMOSOME; PRIORITY JOURNAL;

ADOLESCENT; ADULT; AGED; ANTINEOPLASTIC AGENTS; DRUG RESISTANCE, NEOPLASM; FEMALE; FUSION PROTEINS, BCR-ABL; GENOTYPE; HUMANS; LEUKEMIA, LYMPHOCYTIC, ACUTE; LEUKEMIA, MYELOID, CHRONIC; LEUKEMIA, MYELOID, PHILADELPHIA-POSITIVE; MALE; MIDDLE AGED; MUTATION; NEUTROPENIA; PIPERAZINES; PROTEIN KINASE INHIBITORS; PROTEIN-TYROSINE KINASES; PYRIMIDINES; THIAZOLES;

EID: 33745102555     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJMoa055229     Document Type: Article

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