Interleukin 18 enhances Fas ligand expression and induces apoptosis in Fas-expressing human myelomonocytic KG-1 cells

Anticancer Research

Volumn 17, Issue 5 A, 1997, Pages 3253-3258

  Ohtsuki, Takashi ^a   Micallef, Mark J ^a   Kohno, Keizo ^a   Tanimoto, Tadao ^a   Ikeda, Masao ^a   Kurimoto, Masashi ^a  

^a HAYASHIBARA BIOCHEMICAL LABORATORIES INC   (Japan)

Author keywords

Apoptosis; Fas antigen; IFN ; IL 18; p53

Indexed keywords

CYTOKINE; DNA FRAGMENT; FAS ANTIGEN; GAMMA INTERFERON; INTERLEUKIN 18; LIGAND; MESSENGER RNA; PROTEIN P53; RECEPTOR; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CONTROLLED STUDY; ETIOLOGY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION;

APOPTOSIS; CYTOKINES; DNA FRAGMENTATION; DNA, NEOPLASM; FAS LIGAND PROTEIN; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; INTERFERON TYPE II; INTERLEUKIN-18; LEUKEMIA, MYELOMONOCYTIC, ACUTE; MEMBRANE GLYCOPROTEINS; RNA, MESSENGER; TIME FACTORS; TUMOR CELLS, CULTURED;

EID: 0030728769     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. MacDonald 1, Wang H, Grand R, Armitage RJ, Fanslow WC, Gregory CD and Gordon J: Transforming growth factor-ß1 cooperates with antiimmunoglobulin for the induction of apoptosis in group 1 (biopsy-like) Burkitt Iymphoma cell lines. Blood 87: 1147-1154, 1996.
2. Ishida Y, Agata Y, Shibahara K and Honjo T: Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death. EMBO J 11: 3887-3895, 1992.
3. Deng G and Podack ER: Suppression of apoptosis in a cytotoxic T-cell line by interleukin 2-mediated gene transcription and deregulated expression of the protooncogene bcl-2. Proc Natl Acad Sci USA 90: 2189-2193, 1993.
4. Okamura H, Tsutsui H, Komatsu T, Yutsudo M, Harura A, Tanimoto T, Torigoe K, Okura T, Nukada Y, Hattori K, Akita K, Namba M, Tanabe F, Konishi K, Fukuda S and Kurimoto M: Cloning of a new cytokine that induces IFN-γ production by T cells. Nature 378: 88-91. 1995.
5. Kohno K, Kataoka J, Ohtsuki T, Suemoto Y, Okamoto 1, Usui M, Ikeda M and Kurimoto M: IFN-γ-inducing factor (IGIF) is a costimulatory factor on the activation of Th1 but not Th2 cells and exerts its effect independently of IL-12. J Immunol 1997.
6. Ushio S, Namba M, Okura T, Hattori K, Nukada Y, Akita K, Tanabe F, Konishi K, Micallef M, Fujii M, Torigoe K, Tanimoto T, Fukuda S, Ikeda M, Okamura H and Kurimoto M: Cloning of the cDNA for human IFN-γ-inducing factor, expression in Escherichia coli and studies on the biological activities of the protein. J Immunol 156: 4274-4279, 1996.
7. Micallef MJ, Ohtsuki T, Kohno K, Tanabe F, Ushio S, Namba M, Tanimoto T, Torigoe K, Fujii M, Ikeda M, Fukuda S and Kurimoto M: Interferon-γ-inducing factor enhances T helper 1 cytokine production by stimulated human T cells: synergism with interleukin-12 for interferon-γ production. Europ J Immunol 26: 1647-1651, 1996.
8. Tsutsui H, Nakanishi K, Matsui K, Higashino K, Okamura H, Miyazawa Y and Kaneda K: IFN-y-inducing factor up-regulates Fas ligand-mediated cytotoxic activity of murine natural killer cell clones. J Immunol 157: 3967-3973, 1996.
9. Micallef MJ, Yoshida K, Kawai S, Hanaya T, Kohno K, Arai S, Tanimoto T, Torigoe K, Fujii M, Ikeda M and Kurimoto M: In vivo antitumor effects of murine interferon-γ-inducing factor/interleukin-18 in mice hearing syngeneic Meth A sarcoma malignant ascites. Cancer Immunol Immunother 43: 361-367, 1997.
10. Suda T, Takahashi T, Golstein P and Nagata S: Molecular cloning and expression of the Fas ligand, a novel member of the tumor necrosis factor family. Cell 75: 1169-1178, 1993.
11. Dhein J, Walczak H, Baumler C, Dehatin K-M. and Krammer PH: Autocrine T-cell suicide mediated by APO-1/(Fas/CD95). Nature 373: 438-441, 1995.
12. Alderson MR, Tough TW, Davis-Smith T, Braddy S, Falk B, Schooley KA, Goodwin RG, Smith CA, Ramsdell F and Lynch DH: Fas ligand mediates activation-induced cell death in human lymphocytes. J Exp Med 181: 71-77, 1995.
13. Friesen C, Herr 1, Krammer PH and Debatin K-M: Involvement of the CD95 (APO-1/Fas) receptorAigand system in drug-induced apoptosis in leukemia cells. Nature Med 2: 574-577, 1996.
14. Nicoletti 1, Migliorati G, Pagliacci MC, Grigani F and Riccardi C: A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry. J Immunol Meth 139: 271-279, 1991.
15. Kirks W, Schone S, Uphoff C, Quentmeier H, Pradella S and Drexler HG: Expression and function of CD95 (Fas/APO-1) in leukaemia-lymphoma tumour lines. Brit J Haem 96: 584-593, 1997.
16. Weller M, Constan DB, Malipiero U and Fontana A: Transforming growth factor-ß2 induces apoptosis of murine T cell clones without down-regulating bcl-2 mRNA expression. Europ J Immunol 24: 1293-1300, 1994.
17. Dulic V, Kaufmann WK Wilson SJ, Tlsty TD, Lees E, Harper JW, Elledge SJ and Reed Sl: p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest, Cell 76: 1013-1023, 1994.
18. Owen-Schaub L B, Zhang W, Cusack JC, Angelo LS, Santee SM, Fujiwara T, Roth JA, Deisseroth AB, Zhang W-W, Kruzel W and Radinsky R: Wild-type human p53 and a temperature-sensitive mutant induce Fas/APO-1 expression. Mol Cell Biol 15: 3032-3040, 1995.
19. Liles WC, Kiener PA, Ledbetter JA, Aruffo A and Klebanoff SJ: Differential expression of Fas (CD95) and Fas ligand on normal human phagocytes: Implications for the regulation of apoptosis in neutrophils. J Exp Med 184: 429440, 1996.
20. Selleri C, Sato T, Del Vecchio L, Luciano L, Barret AJ, Rotoli B, Young NS and Maciejewski JP: Involvement of Fas-mediated apoptosis in the inhibitory effects of interferon-a in chronic myelogenous leukemia. Blood 89: 957-964, 1997.