-
1
-
-
79954524112
-
Mechanism of cell adaptation: When and how do cancer cells develop chemoresistance?
-
Fodale V, Pierobon M, Liotta L, Petricoin E. Mechanism of cell adaptation: when and how do cancer cells develop chemoresistance? Cancer J 2011;17:89-95.
-
(2011)
Cancer J
, vol.17
, pp. 89-95
-
-
Fodale, V.1
Pierobon, M.2
Liotta, L.3
Petricoin, E.4
-
2
-
-
79961172897
-
Degrade, move, regroup: Signaling control of splicing proteins
-
Heyd F, Lynch KW. Degrade, move, regroup: signaling control of splicing proteins. Trends Biochem Sci 2011;36:397-404.
-
(2011)
Trends Biochem Sci
, vol.36
, pp. 397-404
-
-
Heyd, F.1
Lynch, K.W.2
-
3
-
-
0037069651
-
Signal-dependent regulation of splicing via phosphorylation of Sam68
-
DOI 10.1038/nature01153
-
Matter N, Herrlich P, Konig H. Signal-dependent regulation of splicing via phosphorylation of Sam68. Nature 2002;420:691-5. (Pubitemid 36764503)
-
(2002)
Nature
, vol.420
, Issue.6916
, pp. 691-695
-
-
Matter, N.1
Herrlich, P.2
Konig, H.3
-
4
-
-
78549234102
-
Alternative splicing of caspase 9 is modulated by the phosphoinositide 3-kinase/Akt pathway via phosphorylation of SRp30a
-
Shultz JC, Goehe RW, Wijesinghe DS, Murudkar C, Hawkins AJ, Shay JW, et al. Alternative splicing of caspase 9 is modulated by the phosphoinositide 3-kinase/Akt pathway via phosphorylation of SRp30a. Cancer Res 2010;70:9185-96.
-
(2010)
Cancer Res
, vol.70
, pp. 9185-9196
-
-
Shultz, J.C.1
Goehe, R.W.2
Wijesinghe, D.S.3
Murudkar, C.4
Hawkins, A.J.5
Shay, J.W.6
-
5
-
-
33746516731
-
hnRNP A1 relocalization to the stress granules reflects a role in the stress response
-
DOI 10.1128/MCB.00224-06
-
Guil S, Long JC, Caceres JF. hnRNP A1 relocalization to the stress granules reflects a role in the stress response. Mol Cell Biol 2006;26:5744-58. (Pubitemid 44134331)
-
(2006)
Molecular and Cellular Biology
, vol.26
, Issue.15
, pp. 5744-5758
-
-
Guil, S.1
Long, J.C.2
Caceres, J.F.3
-
6
-
-
0007570010
-
The MKK(3/6)-p38-signaling cascade alters the subcellular distribution of hnRNP A1 and modulates alternative splicing regulation
-
DOI 10.1083/jcb.149.2.307
-
van der Houven van Oordt W, Diaz-Meco MT, Lozano J, Krainer AR, Moscat J, Caceres JF. The MKK(3/6)-p38-signaling cascade alters the subcellular distribution of hnRNP A1 and modulates alternative splicing regulation. J Cell Biol 2000;149:307-16. (Pubitemid 30227149)
-
(2000)
Journal of Cell Biology
, vol.149
, Issue.2
, pp. 307-316
-
-
Van Oordt, W.V.D.H.1
Diaz-Meco, M.T.2
Lozano, J.3
Krainer, A.R.4
Moscat, J.5
Caceres, J.F.6
-
7
-
-
14844367002
-
Regulation of heterogenous nuclear ribonucleoprotein A1 transport by phosphorylation in cells stressed by osmotic shock
-
DOI 10.1073/pnas.0409889102
-
Allemand E, Guil S, Myers M, Moscat J, Caceres JF, Krainer AR. Regulation of heterogenous nuclear ribonucleoprotein A1 transport by phosphorylation in cells stressed by osmotic shock. Proc Natl Acad Sci U S A 2005;102:3605-10. (Pubitemid 40354658)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.10
, pp. 3605-3610
-
-
Allemand, E.1
Guil, S.2
Myers, M.3
Moscat, J.4
Caceres, J.F.5
Krainer, A.R.6
-
8
-
-
56549101959
-
Alternative isoform regulation in human tissue transcriptomes
-
DOI 10.1038/nature07509, PII NATURE07509
-
Wang ET, Sandberg R, Luo S, Khrebtukova I, Zhang L, Mayr C, et al. Alternative isoform regulation in human tissue transcriptomes. Nature 2008;456:470-6. (Pubitemid 352759009)
-
(2008)
Nature
, vol.456
, Issue.7221
, pp. 470-476
-
-
Wang, E.T.1
Sandberg, R.2
Luo, S.3
Khrebtukova, I.4
Zhang, L.5
Mayr, C.6
Kingsmore, S.F.7
Schroth, G.P.8
Burge, C.B.9
-
9
-
-
33745899048
-
Alternative Splicing: New Insights from Global Analyses
-
DOI 10.1016/j.cell.2006.06.023, PII S0092867406008178
-
Blencowe BJ. Alternative splicing: new insights from global analyses. Cell 2006;126:37-47. (Pubitemid 44040990)
-
(2006)
Cell
, vol.126
, Issue.1
, pp. 37-47
-
-
Blencowe, B.J.1
-
10
-
-
0035393343
-
Genome-wide detection of alternative splicing in expressed sequences of human genes
-
Modrek B, Resch A, Grasso C, Lee C. Genome-wide detection of alternative splicing in expressed sequences of human genes. Nucleic Acids Res 2001;29:2850-9. (Pubitemid 32685050)
-
(2001)
Nucleic Acids Research
, vol.29
, Issue.13
, pp. 2850-2859
-
-
Modrek, B.1
Resch, A.2
Grasso, C.3
Lee, C.4
-
11
-
-
34347237604
-
Genomic analysis of RNA alternative splicing in cancers
-
Xing Y. Genomic analysis of RNA alternative splicing in cancers. Front Biosci 2007;12:4034-41.
-
(2007)
Front Biosci
, vol.12
, pp. 4034-4041
-
-
Xing, Y.1
-
13
-
-
0035370526
-
Spliceosomal UsnRNP biogenesis, structure and function
-
DOI 10.1016/S0955-0674(00)00211-8
-
Will CL, Luhrmann R. Spliceosomal UsnRNP biogenesis, structure and function. Curr Opin Cell Biol 2001;13:290-301. (Pubitemid 32429493)
-
(2001)
Current Opinion in Cell Biology
, vol.13
, Issue.3
, pp. 290-301
-
-
Will, C.L.1
Luhrmann, R.2
-
14
-
-
0035370845
-
Pre-mRNA splicing in the new millennium
-
DOI 10.1016/S0955-0674(00)00212-X
-
Hastings ML, Krainer AR. Pre-mRNA splicing in the new millennium. Curr Opin Cell Biol 2001;13:302-9. (Pubitemid 32429494)
-
(2001)
Current Opinion in Cell Biology
, vol.13
, Issue.3
, pp. 302-309
-
-
Hastings, M.L.1
Krainer, A.R.2
-
15
-
-
78449290661
-
The spliceosomal proteome: At the heart of the largest cellular ribonucleoprotein machine
-
Valadkhan S, Jaladat Y. The spliceosomal proteome: at the heart of the largest cellular ribonucleoprotein machine. Proteomics 2010;10:4128-41.
-
(2010)
Proteomics
, vol.10
, pp. 4128-4141
-
-
Valadkhan, S.1
Jaladat, Y.2
-
16
-
-
0013394889
-
Mechanisms of alternative pre-messenger RNA splicing
-
DOI 10.1146/annurev.biochem.72.121801.161720
-
Black DL. Mechanisms of alternative pre-messenger RNA splicing. Annu Rev Biochem 2003;72:291-336. (Pubitemid 36930448)
-
(2003)
Annual Review of Biochemistry
, vol.72
, pp. 291-336
-
-
Black, D.L.1
-
17
-
-
21244439380
-
Regulation of apoptosis by alternative pre-mRNA splicing
-
DOI 10.1016/j.molcel.2005.05.026, PII S1097276505013754
-
Schwerk C, Schulze-Osthoff K. Regulation of apoptosis by alternative premRNA splicing. Mol Cell 2005;19:1-13. (Pubitemid 40884653)
-
(2005)
Molecular Cell
, vol.19
, Issue.1
, pp. 1-13
-
-
Schwerk, C.1
Schulze-Osthoff, K.2
-
18
-
-
0031711073
-
Mass spectrometry and EST-database searching allows characterization of the multi-protein spliceosome complex
-
DOI 10.1038/1700
-
Neubauer G, King A, Rappsilber J, Calvio C, Watson M, Ajuh P, et al. Mass spectrometry and EST-database searching allows characterization of the multi-protein spliceosome complex. Nat Genet 1998;20:46-50. (Pubitemid 28410342)
-
(1998)
Nature Genetics
, vol.20
, Issue.1
, pp. 46-50
-
-
Neubauer, G.1
King, A.2
Rappsilber, J.3
Calvio, C.4
Watson, M.5
Ajuh, P.6
Sleeman, J.7
Lamond, A.8
Mann, M.9
-
19
-
-
0036674269
-
Large-scale proteomic analysis of the human spliceosome
-
DOI 10.1101/gr.473902
-
Rappsilber J, Ryder U, Lamond AI, Mann M. Large-scale proteomic analysis of the human spliceosome. Genome Res 2002;12:1231-45. (Pubitemid 41264425)
-
(2002)
Genome Research
, vol.12
, Issue.8
, pp. 1231-1245
-
-
Rappsilber, J.1
Ryder, U.2
Lamond, A.I.3
Mann, M.4
-
21
-
-
77956927823
-
The nuclear-retained noncoding RNA MALAT1 regulates alternative splicing by modulating SR splicing factor phosphorylation
-
Tripathi V, Ellis JD, Shen Z, Song DY, Pan Q, Watt AT, et al. The nuclear-retained noncoding RNA MALAT1 regulates alternative splicing by modulating SR splicing factor phosphorylation. Mol Cell 2010;39:925-38.
-
(2010)
Mol Cell
, vol.39
, pp. 925-938
-
-
Tripathi, V.1
Ellis, J.D.2
Shen, Z.3
Song, D.Y.4
Pan, Q.5
Watt, A.T.6
-
22
-
-
0029767662
-
SR proteins and splicing control
-
Manley JL, Tacke R. SR proteins and splicing control. Genes Dev 1996;10:1569-79. (Pubitemid 26268863)
-
(1996)
Genes and Development
, vol.10
, Issue.13
, pp. 1569-1579
-
-
Manley, J.L.1
Tacke, R.2
-
23
-
-
0033835333
-
Sorting out the complexity of SR protein functions
-
Graveley BR. Sorting out the complexity of SR protein functions. RNA 2000;6:1197-211.
-
(2000)
RNA
, vol.6
, pp. 1197-1211
-
-
Graveley, B.R.1
-
24
-
-
0028061367
-
Function of conserved domains of hnRNP A1 and other hnRNP A/B proteins
-
Mayeda A, Munroe SH, Caceres JF, Krainer AR. Function of conserved domains of hnRNP A1 and other hnRNP A/B proteins. Embo J 1994;13:5483-95. (Pubitemid 24351827)
-
(1994)
EMBO Journal
, vol.13
, Issue.22
, pp. 5483-5495
-
-
Mayeda, A.1
Munroe, S.H.2
Caceres, J.F.3
Krainer, A.R.4
-
25
-
-
38049045547
-
Ordered multi-site phosphorylation of the splicing factor ASF/SF2 by SRPK1
-
Ma CT, Velazquez-Dones A, Hagopian JC, Ghosh G, Fu XD, Adams JA. Ordered multi-site phosphorylation of the splicing factor ASF/SF2 by SRPK1. J Mol Biol 2008;376:55-68.
-
(2008)
J Mol Biol
, vol.376
, pp. 55-68
-
-
Ma, C.T.1
Velazquez-Dones, A.2
Hagopian, J.C.3
Ghosh, G.4
Fu, X.D.5
Adams, J.A.6
-
26
-
-
0030863326
-
In vivo regulation of alternative pre-mRNA splicing by the Clk1 protein kinase
-
Duncan PI, Stojdl DF, Marius RM, Bell JC. In vivo regulation of alternative premRNA splicing by the Clk1 protein kinase. Mol Cell Biol 1997;17:5996-6001. (Pubitemid 27411107)
-
(1997)
Molecular and Cellular Biology
, vol.17
, Issue.10
, pp. 5996-6001
-
-
Duncan, P.I.1
Stojdl, D.F.2
Marius, R.M.3
Bell, J.C.4
-
27
-
-
0030028882
-
The Clk/Sty protein kinase phosphorylates SR splicing factors and regulates their intranuclear distribution
-
Colwill K, Pawson T, Andrews B, Prasad J, Manley JL, Bell JC, et al. The Clk/Sty protein kinase phosphorylates SR splicing factors and regulates their intranuclear distribution. Embo J 1996;15:265-75. (Pubitemid 26029629)
-
(1996)
EMBO Journal
, vol.15
, Issue.2
, pp. 265-275
-
-
Colwill, K.1
Pawson, T.2
Andrews, B.3
Prasad, J.4
Manley, J.L.5
Bell, J.C.6
Duncan, P.I.7
-
28
-
-
78049448047
-
hnRNP L regulates the tumorigenic capacity of lung cancer xenografts in mice via caspase-9 pre-mRNA processing
-
Goehe RW, Shultz JC, Murudkar C, Usanovic S, Lamour NF, Massey DH, et al. hnRNP L regulates the tumorigenic capacity of lung cancer xenografts in mice via caspase-9 pre-mRNA processing. J Clin Invest 2010;120:3923-39.
-
(2010)
J Clin Invest
, vol.120
, pp. 3923-3939
-
-
Goehe, R.W.1
Shultz, J.C.2
Murudkar, C.3
Usanovic, S.4
Lamour, N.F.5
Massey, D.H.6
-
29
-
-
0032547829
-
Serine phosphorylation of SR proteins is required for their recruitment to sites of transcription in vivo
-
DOI 10.1083/jcb.143.2.297
-
Misteli T, Caceres JF, Clement JQ, Krainer AR, Wilkinson MF, Spector DL. Serine phosphorylation of SR proteins is required for their recruitment to sites of transcription in vivo. J Cell Biol 1998;143:297-307. (Pubitemid 28487851)
-
(1998)
Journal of Cell Biology
, vol.143
, Issue.2
, pp. 297-307
-
-
Misteli, T.1
Caceres, J.F.2
Clement, J.Q.3
Krainer, A.R.4
Wilkinson, M.F.5
Spector, D.L.6
-
30
-
-
0026731973
-
Ser/Thr-specific protein phosphatases are required for both catalytic steps of pre-mRNA splicing
-
Mermoud JE, Cohen P, Lamond AI. Ser/Thr-specific protein phosphatases are required for both catalytic steps of pre-mRNA splicing. Nucleic Acids Res 1992;20:5263-9.
-
(1992)
Nucleic Acids Res
, vol.20
, pp. 5263-5269
-
-
Mermoud, J.E.1
Cohen, P.2
Lamond, A.I.3
-
31
-
-
27644592554
-
Dephosphorylation-dependent sorting of SR splicing factors during mRNP maturation
-
DOI 10.1016/j.molcel.2005.09.015, PII S1097276505016369
-
Lin S, Xiao R, Sun P, Xu X, Fu XD. Dephosphorylation-dependent sorting of SR splicing factors during mRNP maturation. Mol Cell 2005;20:413-25. (Pubitemid 41572298)
-
(2005)
Molecular Cell
, vol.20
, Issue.3
, pp. 413-425
-
-
Lin, S.1
Xiao, R.2
Sun, P.3
Xu, X.4
Fu, X.-D.5
-
32
-
-
0037451327
-
A novel splicing regulator shares a nuclear import pathway with SR proteins
-
Lai MC, Kuo HW, Chang WC, Tarn WY. A novel splicing regulator shares a nuclear import pathway with SR proteins. Embo J 2003;22:1359-69.
-
(2003)
Embo J
, vol.22
, pp. 1359-1369
-
-
Lai, M.C.1
Kuo, H.W.2
Chang, W.C.3
Tarn, W.Y.4
-
33
-
-
0035898616
-
The RNA binding protein YB-1 binds A/C-rich exon enhancers and stimulates splicing of the CD44 alternative exon v4
-
DOI 10.1093/emboj/20.14.3821
-
Stickeler E, Fraser SD, Honig A, Chen AL, Berget SM, Cooper TA. The RNA binding protein YB-1 binds A/C-rich exon enhancers and stimulates splicing of the CD44 alternative exon v4. Embo J 2001;20:3821-30. (Pubitemid 32691793)
-
(2001)
EMBO Journal
, vol.20
, Issue.14
, pp. 3821-3830
-
-
Stickeler, E.1
Fraser, S.D.2
Honig, A.3
Chen, A.L.4
Berget, S.M.5
Cooper, T.A.6
-
34
-
-
34548600067
-
U2AF-homology motif interactions are required for alternative splicing regulation by SPF45
-
Corsini L, Bonna S, Basquin J, Hothorn M, Scheffzek K, Valcarcel J, et al. U2AF-homology motif interactions are required for alternative splicing regulation by SPF45. Nat Struct Mol Biol 2007;14:620-9.
-
(2007)
Nat Struct Mol Biol
, vol.14
, pp. 620-629
-
-
Corsini, L.1
Bonna, S.2
Basquin, J.3
Hothorn, M.4
Scheffzek, K.5
Valcarcel, J.6
-
35
-
-
0038401969
-
Role of the modular domains of SR proteins in subnuclear localization and alternative splicing specificity
-
DOI 10.1083/jcb.138.2.225
-
Caceres JF, Misteli T, Screaton GR, Spector DL, Krainer AR. Role of the modular domains of SR proteins in subnuclear localization and alternative splicing specificity. J Cell Biol 1997;138:225-38. (Pubitemid 27323527)
-
(1997)
Journal of Cell Biology
, vol.138
, Issue.2
, pp. 225-238
-
-
Caceres, J.F.1
Misteli, T.2
Screaton, G.R.3
Spector, D.L.4
Krainer, A.R.5
-
36
-
-
0344074646
-
Regulated tissue-specific expression of antagonistic pre-mRNA splicing factors
-
Hanamura A, Caceres JF, Mayeda A, Franza Jr BR, Krainer AR. Regulated tissue-specific expression of antagonistic pre-mRNA splicing factors. RNA 1998;4:430-44. (Pubitemid 28160784)
-
(1998)
RNA
, vol.4
, Issue.4
, pp. 430-444
-
-
Hanamura, A.1
Caceres, J.F.2
Mayeda, A.3
Franza Jr., B.R.4
Krainer, A.R.5
-
37
-
-
50849145126
-
Tissue-specific splicing factor gene expression signatures
-
Grosso AR, Gomes AQ, Barbosa-Morais NL, Caldeira S, Thorne NP, Grech G, et al. Tissue-specific splicing factor gene expression signatures. Nucleic Acids Res 2008;36:4823-32.
-
(2008)
Nucleic Acids Res
, vol.36
, pp. 4823-4832
-
-
Grosso, A.R.1
Gomes, A.Q.2
Barbosa-Morais, N.L.3
Caldeira, S.4
Thorne, N.P.5
Grech, G.6
-
38
-
-
55549143293
-
The emerging role of splicing factors in cancer
-
Grosso AR, Martins S, Carmo-Fonseca M. The emerging role of splicing factors in cancer. EMBO Rep 2008;9:1087-93.
-
(2008)
EMBO Rep
, vol.9
, pp. 1087-1093
-
-
Grosso, A.R.1
Martins, S.2
Carmo-Fonseca, M.3
-
39
-
-
0142182109
-
Human SPF45, a Splicing Factor, Has Limited Expression in Normal Tissues, Is Overexpressed in Many Tumors, and Can Confer a Multidrug-Resistant Phenotype to Cells
-
Sampath J, Long PR, Shepard RL, Xia X, Devanarayan V, Sandusky GE, et al. Human SPF45, a splicing factor, has limited expression in normal tissues, is overexpressed in many tumors, and can confer a multidrug-resistant phenotype to cells. Am J Pathol 2003;163:1781-90. (Pubitemid 37310010)
-
(2003)
American Journal of Pathology
, vol.163
, Issue.5
, pp. 1781-1790
-
-
Sampath, J.1
Long, P.R.2
Shepard, R.L.3
Xia, X.4
Devanarayan, V.5
Sandusky, G.E.6
Perry III, W.L.7
Dantzig, A.H.8
Williamson, M.9
Rolfe, M.10
Moore, R.E.11
-
40
-
-
23044441609
-
Human splicing factor SPF45 (RBM17) confers broad multidrug resistance to anticancer drugs when overexpressed - A phenotype partially reversed by selective estrogen receptor modulators
-
DOI 10.1158/0008-5472.CAN-03-3675
-
Perry WL, 3rd, Shepard RL, Sampath J, Yaden B, Chin WW, Iversen PW, et al. Human splicing factor SPF45 (RBM17) confers broad multidrug resistance to anticancer drugs when overexpressed-a phenotype partially reversed by selective estrogen receptor modulators. Cancer Res 2005;65:6593-600. (Pubitemid 41060695)
-
(2005)
Cancer Research
, vol.65
, Issue.15
, pp. 6593-6600
-
-
Perry III, W.L.1
Shepard, R.L.2
Sampath, J.3
Yaden, B.4
Chin, W.W.5
Iversen, P.W.6
Jin, S.7
Lesoon, A.8
O'Brien, K.A.9
Peek, V.L.10
Rolfe, M.11
Shyjan, A.12
Tighe, M.13
Williamson, M.14
Krishnan, V.15
Moore, R.E.16
Dantzig, A.H.17
-
41
-
-
0037013146
-
Splicing regulation at the second catalytic step by Sex-lethal involves 3′ splice site recognition by SPF45
-
DOI 10.1016/S0092-8674(02)00730-4
-
Lallena MJ, Chalmers KJ, Llamazares S, Lamond AI, Valcarcel J. Splicing regulation at the second catalytic step by Sex-lethal involves 3′ splice site recognition by SPF45. Cell 2002;109:285-96. (Pubitemid 34606872)
-
(2002)
Cell
, vol.109
, Issue.3
, pp. 285-296
-
-
Lallena, M.J.1
Chalmers, K.J.2
Llamazares, S.3
Lamond, A.I.4
Valcarcel, J.5
-
42
-
-
0033200012
-
G-patch: A new conserved domain in eukaryotic RNA-processing proteins and type D retroviral polyproteins
-
DOI 10.1016/S0968-0004(99)01437-1, PII S0968000499014371
-
Aravind L, Koonin EV. G-patch: a new conserved domain in eukaryotic RNA-processing proteins and type D retroviral polyproteins. Trends Biochem Sci 1999;24:342-4. (Pubitemid 29421808)
-
(1999)
Trends in Biochemical Sciences
, vol.24
, Issue.9
, pp. 342-344
-
-
Aravind, L.1
Koonin, E.V.2
-
43
-
-
8644284892
-
Interaction between a G-patch protein and a spliceosomal DEXD/H-box ATPase that is critical for splicing
-
DOI 10.1128/MCB.24.23.10101-10110.2004
-
Silverman EJ, Maeda A, Wei J, Smith P, Beggs JD, Lin RJ. Interaction between a G-patch protein and a spliceosomal DEXD/H-box ATPase that is critical for splicing. Mol Cell Biol 2004;24:10101-10. (Pubitemid 39507850)
-
(2004)
Molecular and Cellular Biology
, vol.24
, Issue.23
, pp. 10101-10110
-
-
Silverman, E.J.1
Maeda, A.2
Wei, J.3
Smith, P.4
Beggs, J.D.5
Lin, R.-J.6
-
44
-
-
4944256316
-
Proteinases of betaretroviruses bind single-stranded nucleic acids through a novel interaction module, the G-patch
-
DOI 10.1016/j.febslet.2004.09.010, PII S001457930401124X
-
Svec M, Bauerova H, Pichova I, Konvalinka J, Strisovsky K. Proteinases of betaretroviruses bind single-stranded nucleic acids through a novel interaction module, the G-patch. FEBS Lett 2004;576:271-6. (Pubitemid 39330496)
-
(2004)
FEBS Letters
, vol.576
, Issue.1-2
, pp. 271-276
-
-
Svec, M.1
Bauerova, H.2
Pichova, I.3
Konvalinka, J.4
Strisovsky, K.5
-
45
-
-
33645914121
-
Structural and functional characterization of the TgDRE multidomain protein, a DNA repair enzyme from Toxoplasma gondii
-
Frenal K, Callebaut I, Wecker K, Prochnicka-Chalufour A, Dendouga N, Zinn-Justin S, et al. Structural and functional characterization of the TgDRE multidomain protein, a DNA repair enzyme from Toxoplasma gondii. Biochemistry 2006;45:4867-74.
-
(2006)
Biochemistry
, vol.45
, pp. 4867-4874
-
-
Frenal, K.1
Callebaut, I.2
Wecker, K.3
Prochnicka-Chalufour, A.4
Dendouga, N.5
Zinn-Justin, S.6
-
46
-
-
84858009379
-
-
submitted for publication
-
Liu Y, Conaway L, Al-Ayoubi AM, Zheng H, Bethard JR, Pierce JY, et al. Cdc2-like kinase 1 (Clk1) phosphorylates the alternative mRNA splicing factor 45 (SPF45) and regulates its subnuclear localization, degradation and splice-site utilization, submitted for publication.
-
Cdc2-like Kinase 1 (Clk1) Phosphorylates the Alternative MRNA Splicing Factor 45 (SPF45) and Regulates Its Subnuclear Localization, Degradation and Splice-site Utilization
-
-
Liu, Y.1
Conaway, L.2
Al-Ayoubi, A.M.3
Zheng, H.4
Bethard, J.R.5
Pierce, J.Y.6
-
47
-
-
23744492690
-
Regulation of fas alternative splicing by antagonistic effects of TIA-1 and PTB on exon definition
-
DOI 10.1016/j.molcel.2005.06.015, PII S1097276505014188
-
Izquierdo JM, Majos N, Bonnal S, Martinez C, Castelo R, Guigo R, et al. Regulation of Fas alternative splicing by antagonistic effects of TIA-1 and PTB on exon definition. Mol Cell 2005;19:475-84. (Pubitemid 41140005)
-
(2005)
Molecular Cell
, vol.19
, Issue.4
, pp. 475-484
-
-
Izquierdo, J.M.1
Majos, N.2
Bonnal, S.3
Martinez, C.4
Castelo, R.5
Guigo, R.6
Bilbao, D.7
Valcarcel, J.8
-
48
-
-
38349085591
-
Regulation of alternative splicing by reversible protein phosphorylation
-
Stamm S. Regulation of alternative splicing by reversible protein phosphorylation. J Biol Chem 2008;283:1223-7.
-
(2008)
J Biol Chem
, vol.283
, pp. 1223-1227
-
-
Stamm, S.1
-
49
-
-
0038351827
-
Identification of novel ERK2 substrates through use of an engineered kinase and ATP analogs
-
DOI 10.1074/jbc.M300485200
-
Eblen ST, Kumar NV, Shah K, Henderson MJ, Watts CK, Shokat KM, et al. Identification of novel ERK2 substrates through use of an engineered kinase and ATP analogs. J Biol Chem 2003;278:14926-35. (Pubitemid 36799822)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.17
, pp. 14926-14935
-
-
Eblen, S.T.1
Kumar, N.V.2
Shah, K.3
Henderson, M.J.4
Watts, C.K.W.5
Shokat, K.M.6
Weber, M.J.7
-
50
-
-
84858009436
-
-
submitted for publication
-
Al-Ayoubi AM, Zheng H, Liu Y, Bai T, Eblen ST. ERK2 phosphorylation of splicing factor 45 (SPF45) regulates SPF45 alternative splice site utilization and downstream gene expression, submitted for publication.
-
ERK2 Phosphorylation of Splicing Factor 45 (SPF45) Regulates SPF45 Alternative Splice Site Utilization and Downstream Gene Expression
-
-
Al-Ayoubi, A.M.1
Zheng, H.2
Liu, Y.3
Bai, T.4
Eblen, S.T.5
-
51
-
-
34548480966
-
Signals, pathways and splicing regulation
-
DOI 10.1016/j.biocel.2007.04.004, PII S1357272507001185
-
Blaustein M, Pelisch F, Srebrow A. Signals, pathways and splicing regulation. Int J Biochem Cell Biol 2007;39:2031-48. (Pubitemid 47376826)
-
(2007)
International Journal of Biochemistry and Cell Biology
, vol.39
, Issue.11
, pp. 2031-2048
-
-
Blaustein, M.1
Pelisch, F.2
Srebrow, A.3
-
52
-
-
0033800091
-
Multicellular resistance: A paradigm for clinical resistance?
-
Desoize B, Jardillier J. Multicellular resistance: a paradigm for clinical resistance? Crit Rev Oncol Hematol 2000;36:193-207.
-
(2000)
Crit Rev Oncol Hematol
, vol.36
, pp. 193-207
-
-
Desoize, B.1
Jardillier, J.2
-
53
-
-
0035184068
-
Beta1-integrins regulate the formation and adhesion of ovarian carcinoma multicellular spheroids
-
Casey RC, Burleson KM, Skubitz KM, Pambuccian SE, Oegema Jr TR, Ruff LE, et al. Beta 1-integrins regulate the formation and adhesion of ovarian carcinoma multicellular spheroids. Am J Pathol 2001;159:2071-80. (Pubitemid 33104261)
-
(2001)
American Journal of Pathology
, vol.159
, Issue.6
, pp. 2071-2080
-
-
Casey, R.C.1
Burleson, K.M.2
Skubitz, K.M.3
Pambuccian, S.E.4
Oegema Jr., T.R.5
Ruff, L.E.6
Skubitz, A.P.N.7
-
54
-
-
63449105639
-
Compact spheroid formation by ovarian cancer cells is associated with contractile behavior and an invasive phenotype
-
Sodek KL, Ringuette MJ, Brown TJ. Compact spheroid formation by ovarian cancer cells is associated with contractile behavior and an invasive phenotype. Int J Cancer 2009;124:2060-70.
-
(2009)
Int J Cancer
, vol.124
, pp. 2060-2070
-
-
Sodek, K.L.1
Ringuette, M.J.2
Brown, T.J.3
-
55
-
-
0027286404
-
Two cDNAs from the plant Arabidopsis thaliana that partially restore recombination proficiency and DNA-damage resistance to E.Coli mutants lacking recombination-intermediate-resolution activities
-
Pang Q, Hays JB, Rajagopal I. Two cDNAs from the plant Arabidopsis thaliana that partially restore recombination proficiency and DNA-damage resistance to E. coli mutants lacking recombination-intermediate-resolution activities. Nucleic Acids Res 1993;21:1647-53. (Pubitemid 23146334)
-
(1993)
Nucleic Acids Research
, vol.21
, Issue.7
, pp. 1647-1653
-
-
Pang, Q.1
Hays, J.B.2
Rajagopal, I.3
-
56
-
-
33846031127
-
Drosophila SPF45: A Bifunctional Protein with Roles in Both Splicing and DNA Repair
-
Chaouki AS, Salz HK. Drosophila SPF45: A Bifunctional Protein with Roles in Both Splicing and DNA Repair. PLoS Genet 2006;2:e178.
-
(2006)
PLoS Genet
, vol.2
-
-
Chaouki, A.S.1
Salz, H.K.2
-
57
-
-
77954662209
-
Holliday junction-binding activity of human SPF45
-
Horikoshi N, Morozumi Y, Takaku M, Takizawa Y, Kurumizaka H. Holliday junction-binding activity of human SPF45. Genes Cells 2010;15:373-83.
-
(2010)
Genes Cells
, vol.15
, pp. 373-383
-
-
Horikoshi, N.1
Morozumi, Y.2
Takaku, M.3
Takizawa, Y.4
Kurumizaka, H.5
-
58
-
-
0033565221
-
SR protein-specific kinase 1 is highly expressed in testis and phosphorylates protamine 1
-
DOI 10.1093/nar/27.14.2972
-
Papoutsopoulou S, Nikolakaki E, Chalepakis G, Kruft V, Chevaillier P, Giannakouros T. SR protein-specific kinase 1 is highly expressed in testis and phosphorylates protamine 1. Nucleic Acids Res 1999;27:2972-80. (Pubitemid 29335720)
-
(1999)
Nucleic Acids Research
, vol.27
, Issue.14
, pp. 2972-2980
-
-
Papoutsopoulou, S.1
Nikolakaki, E.2
Chalepakis, G.3
Kruft, V.4
Chevaillier, P.5
Giannakouros, T.6
-
59
-
-
33947223157
-
Serine-arginine protein kinase 1 overexpression is associated with tumorigenic imbalance in mitogen-activated protein kinase pathways in breast, colonic, and pancreatic carcinomas
-
DOI 10.1158/0008-5472.CAN-06-2969
-
Hayes GM, Carrigan PE, Miller LJ. Serine-arginine protein kinase 1 overexpression is associated with tumorigenic imbalance in mitogen-activated protein kinase pathways in breast, colonic, and pancreatic carcinomas. Cancer Res 2007;67:2072-80. (Pubitemid 46424225)
-
(2007)
Cancer Research
, vol.67
, Issue.5
, pp. 2072-2080
-
-
Hayes, G.M.1
Carrigan, P.E.2
Miller, L.J.3
-
60
-
-
33645746620
-
Targeting the RNA splicing machinery as a novel treatment strategy for pancreatic carcinoma
-
Hayes GM, Carrigan PE, Beck AM, Miller LJ. Targeting the RNA splicing machinery as a novel treatment strategy for pancreatic carcinoma. Cancer Res 2006;66:3819-27.
-
(2006)
Cancer Res
, vol.66
, pp. 3819-3827
-
-
Hayes, G.M.1
Carrigan, P.E.2
Beck, A.M.3
Miller, L.J.4
-
61
-
-
0028225858
-
A ligand-dependent bipartite nuclear targeting signal in the human androgen receptor. Requirement for the DNA-binding domain and modulation by NH2-terminal and carboxyl-terminal sequences
-
Zhou ZX, Sar M, Simental JA, Lane MV, Wilson EM. A ligand-dependent bipartite nuclear targeting signal in the human androgen receptor. Requirement for the DNA-binding domain and modulation by NH2-terminal and carboxyl-terminal sequences. J Biol Chem 1994;269:13115-23.
-
(1994)
J Biol Chem
, vol.269
, pp. 13115-13123
-
-
Zhou, Z.X.1
Sar, M.2
Simental, J.A.3
Lane, M.V.4
Wilson, E.M.5
-
62
-
-
0037447330
-
Constitutive activation of the Ras/mitogen-activated protein kinase signaling pathway promotes androgen hypersensitivity in LNCaP prostate cancer cells
-
Bakin RE, Gioeli D, Sikes RA, Bissonette EA, Weber MJ. Constitutive activation of the Ras/mitogen-activated protein kinase signaling pathway promotes androgen hypersensitivity in LNCaP prostate cancer cells. Cancer Res 2003;63:1981-9. (Pubitemid 36460867)
-
(2003)
Cancer Research
, vol.63
, Issue.8
, pp. 1981-1989
-
-
Bakin, R.E.1
Gioeli, D.2
Sikes, R.A.3
Bissonette, E.A.4
Weber, M.J.5
-
63
-
-
0037447154
-
Attenuation of Ras signaling restores androgen sensitivity to hormone-refractory C4-2 prostate cancer cells
-
Bakin RE, Gioeli D, Bissonette EA, Weber MJ. Attenuation of Ras signaling restores androgen sensitivity to hormone-refractory C4-2 prostate cancer cells. Cancer Res 2003;63:1975-80. (Pubitemid 36460866)
-
(2003)
Cancer Research
, vol.63
, Issue.8
, pp. 1975-1980
-
-
Bakin, R.E.1
Gioeli, D.2
Bissonette, E.A.3
Weber, M.J.4
-
64
-
-
0033555967
-
Activation of mitogen-activated protein kinase associated with prostate cancer progression
-
Gioeli D, Mandell JW, Petroni GR, Frierson Jr HF, Weber MJ. Activation of mitogen-activated protein kinase associated with prostate cancer progression. Cancer Res 1999;59:279-84. (Pubitemid 29048852)
-
(1999)
Cancer Research
, vol.59
, Issue.2
, pp. 279-284
-
-
Gioeli, D.1
Mandell, J.W.2
Petroni, G.R.3
Frierson Jr., H.F.4
Weber, M.J.5
-
65
-
-
19044380048
-
Androgen receptor phosphorylation. Regulation and identification of the phosphorylation sites
-
Gioeli D, Ficarro SB, Kwiek JJ, Aaronson D, Hancock M, Catling AD, et al. Androgen receptor phosphorylation. Regulation and identification of the phosphorylation sites. J Biol Chem 2002;277:29304-1.
-
(2002)
J Biol Chem
, vol.277
, pp. 29304-29311
-
-
Gioeli, D.1
Ficarro, S.B.2
Kwiek, J.J.3
Aaronson, D.4
Hancock, M.5
Catling, A.D.6
-
66
-
-
33344467745
-
Stress kinase signaling regulates androgen receptor phosphorylation, transcription, and localization
-
DOI 10.1210/me.2005-0351
-
Gioeli D, Black BE, Gordon V, Spencer A, Kesler CT, Eblen ST, et al. Stress kinase signaling regulates androgen receptor phosphorylation, transcription, and localization. Mol Endocrinol 2006;20:503-15. (Pubitemid 43291205)
-
(2006)
Molecular Endocrinology
, vol.20
, Issue.3
, pp. 503-515
-
-
Gioeli, D.1
Black, B.E.2
Gordon, V.3
Spencer, A.4
Kesler, C.T.5
Eblen, S.T.6
Paschal, B.M.7
Weber, M.J.8
-
67
-
-
80054931284
-
Alternatively spliced androgen receptor variants
-
Dehm SM, Tindall DJ. Alternatively spliced androgen receptor variants. Endocr Relat Cancer 2011;18:R183-96.
-
(2011)
Endocr Relat Cancer
, vol.18
-
-
Dehm, S.M.1
Tindall, D.J.2
-
68
-
-
0037112372
-
Characterization of a novel androgen receptor mutation in a relapsed CWR22 prostate cancer xenograft and cell line
-
Tepper CG, Boucher DL, Ryan PE, Ma AH, Xia L, Lee LF, et al. Characterization of a novel androgen receptor mutation in a relapsed CWR22 prostate cancer xenograft and cell line. Cancer Res 2002;62:6606-14. (Pubitemid 35364127)
-
(2002)
Cancer Research
, vol.62
, Issue.22
, pp. 6606-6614
-
-
Tepper, C.G.1
Boucher, D.L.2
Ryan, P.E.3
Ma, A.-H.4
Xia, L.5
Lee, L.-F.6
Pretlow, T.G.7
Kung, H.-J.8
-
69
-
-
35148833549
-
Evidence for calpain-mediated androgen receptor cleavage as a mechanism for androgen independence
-
DOI 10.1158/0008-5472.CAN-07-1072
-
Libertini SJ, Tepper CG, Rodriguez V, Asmuth DM, Kung HJ, Mudryj M. Evidence for calpain-mediated androgen receptor cleavage as a mechanism for androgen independence. Cancer Res 2007;67:9001-5. (Pubitemid 47535881)
-
(2007)
Cancer Research
, vol.67
, Issue.19
, pp. 9001-9005
-
-
Libertini, S.J.1
Tepper, C.G.2
Rodriguez, V.3
Asmuth, D.M.4
Kung, H.-J.5
Mudryj, M.6
-
70
-
-
48549089747
-
Splicing of a novel androgenreceptor exongenerates a constitutivelyactive androgenreceptor that mediates prostate cancer therapy resistance
-
Dehm SM, Schmidt LJ, Heemers HV, Vessella RL, Tindall DJ. Splicing of a novel androgenreceptor exongenerates a constitutivelyactive androgenreceptor that mediates prostate cancer therapy resistance. Cancer Res 2008;68:5469-77.
-
(2008)
Cancer Res
, vol.68
, pp. 5469-5477
-
-
Dehm, S.M.1
Schmidt, L.J.2
Heemers, H.V.3
Vessella, R.L.4
Tindall, D.J.5
-
72
-
-
58249110391
-
Ligand-independent androgen receptor variants derived from splicing of cryptic exons signify hormone-refractory prostate cancer
-
Hu R, Dunn TA, Wei S, Isharwal S, Veltri RW, Humphreys E, et al. Ligand-independent androgen receptor variants derived from splicing of cryptic exons signify hormone-refractory prostate cancer. Cancer Res 2009;69:16-22.
-
(2009)
Cancer Res
, vol.69
, pp. 16-22
-
-
Hu, R.1
Dunn, T.A.2
Wei, S.3
Isharwal, S.4
Veltri, R.W.5
Humphreys, E.6
-
73
-
-
79959312739
-
A snapshot of the expression signature of androgen receptor splicing variants and their distinctive transcriptional activities
-
Hu R, Isaacs WB, Luo J. A snapshot of the expression signature of androgen receptor splicing variants and their distinctive transcriptional activities. Prostate 2011;71:1656-67.
-
(2011)
Prostate
, vol.71
, pp. 1656-1667
-
-
Hu, R.1
Isaacs, W.B.2
Luo, J.3
-
74
-
-
74049109753
-
Identification of novel truncated androgen receptor (AR) mutants including unreported pre-mRNA splicing variants in the 22Rv1 hormone-refractory prostate cancer (PCa) cell line
-
Marcias G, Erdmann E, Lapouge G, Siebert C, Barthelemy P, Duclos B, et al. Identification of novel truncated androgen receptor (AR) mutants including unreported pre-mRNA splicing variants in the 22Rv1 hormone-refractory prostate cancer (PCa) cell line. Hum Mutat 2010;31:74-80.
-
(2010)
Hum Mutat
, vol.31
, pp. 74-80
-
-
Marcias, G.1
Erdmann, E.2
Lapouge, G.3
Siebert, C.4
Barthelemy, P.5
Duclos, B.6
-
75
-
-
0033664255
-
How does interferon-alpha exert its antitumour activity in multiple myeloma?
-
Grander D. How does interferon-alpha exert its antitumour activity in multiple myeloma? Acta Oncol 2000;39:801-5.
-
(2000)
Acta Oncol
, vol.39
, pp. 801-805
-
-
Grander, D.1
-
77
-
-
79955909579
-
Immunomodulatory cytokines as therapeutic agents for melanoma
-
Nicholas C, Lesinski GB. Immunomodulatory cytokines as therapeutic agents for melanoma. Immunotherapy 2011;3:673-90.
-
(2011)
Immunotherapy
, vol.3
, pp. 673-690
-
-
Nicholas, C.1
Lesinski, G.B.2
-
78
-
-
0036269757
-
Cancer immunotherapy: The interferon-alpha experience
-
Kirkwood J. Cancer immunotherapy: the interferon-alpha experience. Semin Oncol 2002;29:18-26.
-
(2002)
Semin Oncol
, vol.29
, pp. 18-26
-
-
Kirkwood, J.1
-
80
-
-
0029133702
-
Requirement for MAP kinase (ERK2) activity in interferon alpha- And interferon beta-stimulated gene expression through STAT proteins
-
David M, Petricoin 3rd E, Benjamin C, Pine R, Weber MJ, Larner AC. Requirement for MAP kinase (ERK2) activity in interferon alpha- and interferon beta-stimulated gene expression through STAT proteins. Science 1995;269:1721-3.
-
(1995)
Science
, vol.269
, pp. 1721-1723
-
-
David, M.1
Petricoin III, E.2
Benjamin, C.3
Pine, R.4
Weber, M.J.5
Larner, A.C.6
-
81
-
-
70350435094
-
Interferon-resistant Daudi cell line with a Stat2 defect is resistant to apoptosis induced by chemotherapeutic agents
-
Du Z, Fan M, Kim JG, Eckerle D, Lothstein L, Wei L, et al. Interferon-resistant Daudi cell line with a Stat2 defect is resistant to apoptosis induced by chemotherapeutic agents. J Biol Chem 2009;284:27808-15.
-
(2009)
J Biol Chem
, vol.284
, pp. 27808-27815
-
-
Du, Z.1
Fan, M.2
Kim, J.G.3
Eckerle, D.4
Lothstein, L.5
Wei, L.6
-
82
-
-
0029987787
-
Identification of alternative splicing form of stat2
-
DOI 10.1016/0014-5793(96)00121-4
-
Sugiyama T, Nishio Y, Kishimoto T, Akira S. Identification of alternative splicing form of Stat2. FEBS Lett 1996;381:191-4. (Pubitemid 26080337)
-
(1996)
FEBS Letters
, vol.381
, Issue.3
, pp. 191-194
-
-
Sugiyama, T.1
Nishio, Y.2
Kishimoto, T.3
Akira, S.4
-
83
-
-
0030968438
-
CDK-independent activation of estrogen receptor by cyclin D1
-
DOI 10.1016/S0092-8674(00)81879-6
-
Zwijsen RM, Wientjens E, Klompmaker R, van der Sman J, Bernards R, Michalides RJ. CDK-independent activation of estrogen receptor by cyclin D1. Cell 1997;88:405-15. (Pubitemid 27131382)
-
(1997)
Cell
, vol.88
, Issue.3
, pp. 405-415
-
-
Zwijsen, R.M.L.1
Wientjens, E.2
Klompmaker, R.3
Van Der, S.J.4
Bernards, R.5
Michalides, R.J.A.M.6
-
84
-
-
0030745396
-
Cyclin D1 stimulation of estrogen receptor transcriptional activity independent of cdk4
-
Neuman E, Ladha MH, Lin N, Upton TM, Miller SJ, DiRenzo J, et al. Cyclin D1 stimulation of estrogen receptor transcriptional activity independent of cdk4. Mol Cell Biol 1997;17:5338-47. (Pubitemid 27357632)
-
(1997)
Molecular and Cellular Biology
, vol.17
, Issue.9
, pp. 5338-5347
-
-
Neuman, E.1
Ladha, M.H.2
Lin, N.3
Upton, T.M.4
Miller, S.J.5
Direnzo, J.6
Pestell, R.G.7
Hinds, P.W.8
Dowdy, S.F.9
Brown, M.10
Ewen, M.E.11
-
85
-
-
0032533881
-
Ligand-independent recruitment of steroid receptor coactivators to estrogen receptor by cyclin D1
-
Zwijsen RM, Buckle RS, Hijmans EM, Loomans CJ, Bernards R. Ligand-independent recruitment of steroid receptor coactivators to estrogen receptor by cyclin D1. Genes Dev 1998;12:3488-98. (Pubitemid 28553241)
-
(1998)
Genes and Development
, vol.12
, Issue.22
, pp. 3488-3498
-
-
Zwijsen, R.M.L.1
Buckle, R.S.2
Hijmans, E.M.3
Loomans, C.J.M.4
Bernards, R.5
-
86
-
-
23044508946
-
Cyclin D1 in breast cancer pathogenesis
-
DOI 10.1200/JCO.2005.05.064
-
Arnold A, Papanikolaou A. Cyclin D1 in breast cancer pathogenesis. J Clin Oncol 2005;23:4215-24. (Pubitemid 46211327)
-
(2005)
Journal of Clinical Oncology
, vol.23
, Issue.18
, pp. 4215-4224
-
-
Arnold, A.1
Papanikolaou, A.2
-
87
-
-
0013439945
-
Cycling to cancer with cyclin D1
-
Diehl JA. Cycling to cancer with cyclin D1. Cancer Biol Ther 2002;1:226-31.
-
(2002)
Cancer Biol Ther
, vol.1
, pp. 226-231
-
-
Diehl, J.A.1
-
88
-
-
0028308702
-
Cyclin D1 protein expression and function in human breast cancer
-
DOI 10.1002/ijc.2910570311
-
Bartkova J, Lukas J, Muller H, Lutzhoft D, Strauss M, Bartek J. Cyclin D1 protein expression and function in human breast cancer. Int J Cancer 1994;57:353-61. (Pubitemid 24168609)
-
(1994)
International Journal of Cancer
, vol.57
, Issue.3
, pp. 353-361
-
-
Bartkova, J.1
Lukas, J.2
Muller, H.3
Lutzhoft, D.4
Strauss, M.5
Bartek, J.6
-
89
-
-
0028129951
-
The PRAD-1/cyclin D1 oncogene product accumulates aberrantly in a subset of colorectal carcinomas
-
Bartkova J, Lukas J, Strauss M, Bartek J. The PRAD-1/cyclin D1 oncogene product accumulates aberrantly in a subset of colorectal carcinomas. Int J Cancer 1994;58:568-73. (Pubitemid 24268101)
-
(1994)
International Journal of Cancer
, vol.58
, Issue.4
, pp. 568-573
-
-
Bartkova, J.1
Lukas, J.2
Strauss, M.3
Bartek, J.4
-
90
-
-
0034671768
-
Phosphorylation-dependent regulation of cyclin D1 nuclear export and cyclin D1-dependent cellular transformation
-
DOI 10.1101/gad.854900
-
Alt JR, Cleveland JL, Hannink M, Diehl JA. Phosphorylation-dependent regulation of cyclin D1 nuclear export and cyclin D1-dependent cellular transformation. Genes Dev 2000;14:3102-14. (Pubitemid 32015129)
-
(2000)
Genes and Development
, vol.14
, Issue.24
, pp. 3102-3114
-
-
Alt, J.R.1
Cleveland, J.L.2
Hannink, M.3
Diehl, J.A.4
-
91
-
-
0032533225
-
Glycogen synthase kinase-3beta; regulates cyclin D1 proteolysis and subcellular localization
-
Diehl JA, Cheng M, Roussel MF, Sherr CJ. Glycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localization. Genes Dev 1998;12:3499-511. (Pubitemid 28553242)
-
(1998)
Genes and Development
, vol.12
, Issue.22
, pp. 3499-3511
-
-
Diehl, J.A.1
Cheng, M.2
Roussel, M.F.3
Sherr, C.J.4
-
92
-
-
0034697022
-
Ubiquitination of free cyclin D1 is independent of phosphorylation on threonine 286
-
DOI 10.1074/jbc.275.16.12074
-
Germain D, Russell A, Thompson A, Hendley J. Ubiquitination of free cyclin D1 is independent of phosphorylation on threonine 286. J Biol Chem 2000;275:12074-9. (Pubitemid 30237782)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.16
, pp. 12074-12079
-
-
Germain, D.1
Russell, A.2
Thompson, A.3
Hendley, J.4
-
93
-
-
0029083790
-
Alternate splicing produces a novel cyclin D1 transcript
-
Betticher DC, Thatcher N, Altermatt HJ, Hoban P, Ryder WD, Heighway J. Alternate splicing produces a novel cyclin D1 transcript. Oncogene 1995;11:1005-11.
-
(1995)
Oncogene
, vol.11
, pp. 1005-1011
-
-
Betticher, D.C.1
Thatcher, N.2
Altermatt, H.J.3
Hoban, P.4
Ryder, W.D.5
Heighway, J.6
-
94
-
-
0031586763
-
Cyclin D1 (PRAD1) alternative transcript b: Full-length cDNA cloning and expression in breast cancers
-
DOI 10.1016/S0304-3835(97)04605-3, PII S0304383597046053
-
Hosokawa Y, Gadd M, Smith AP, Koerner FC, Schmidt EV, Arnold A. Cyclin D1 (PRAD1) alternative transcript b: full-length cDNA cloning and expression in breast cancers. Cancer Lett 1997;113:123-30. (Pubitemid 27113238)
-
(1997)
Cancer Letters
, vol.113
, Issue.1-2
, pp. 123-130
-
-
Hosokawa, Y.1
Gadd, M.2
Smith, A.P.3
Koerner, F.C.4
Schmidt, E.V.5
Arnold, A.6
-
95
-
-
48649103464
-
Cyclin D1b is aberrantly regulated in response to therapeutic challenge and promotes resistance to estrogen antagonists
-
Wang Y, Dean JL, Millar EK, Tran TH, McNeil CM, Burd CJ, et al. Cyclin D1b is aberrantly regulated in response to therapeutic challenge and promotes resistance to estrogen antagonists. Cancer Res 2008;68:5628-38.
-
(2008)
Cancer Res
, vol.68
, pp. 5628-5638
-
-
Wang, Y.1
Dean, J.L.2
Millar, E.K.3
Tran, T.H.4
McNeil, C.M.5
Burd, C.J.6
-
96
-
-
33645118564
-
Cyclin D1: Polymorphism, aberrant splicing and cancer risk
-
Knudsen KE, Diehl JA, Haiman CA, Knudsen ES. Cyclin D1: polymorphism, aberrant splicing and cancer risk. Oncogene 2006;25:1620-8.
-
(2006)
Oncogene
, vol.25
, pp. 1620-1628
-
-
Knudsen, K.E.1
Diehl, J.A.2
Haiman, C.A.3
Knudsen, E.S.4
-
97
-
-
77953732182
-
Cyclin D1b in human breast carcinoma and coexpression with cyclin D1a is associated with poor outcome
-
Abramson VG, Troxel AB, Feldman M, Mies C, Wang Y, Sherman L, et al. Cyclin D1b in human breast carcinoma and coexpression with cyclin D1a is associated with poor outcome. Anticancer Res 2010;30:1279-85.
-
(2010)
Anticancer Res
, vol.30
, pp. 1279-1285
-
-
Abramson, V.G.1
Troxel, A.B.2
Feldman, M.3
Mies, C.4
Wang, Y.5
Sherman, L.6
-
98
-
-
65049084565
-
Cyclin D1b protein expression in breast cancer is independent of cyclin D1a and associated with poor disease outcome
-
Millar EK, Dean JL, McNeil CM, O'Toole SA, Henshall SM, Tran T, et al. Cyclin D1b protein expression in breast cancer is independent of cyclin D1a and associated with poor disease outcome. Oncogene 2009;28:1812-20.
-
(2009)
Oncogene
, vol.28
, pp. 1812-1820
-
-
Millar, E.K.1
Dean, J.L.2
McNeil, C.M.3
O'Toole, S.A.4
Henshall, S.M.5
Tran, T.6
-
99
-
-
33144474074
-
Cyclin D1b variant influences prostate cancer growth through aberrant androgen receptor regulation
-
DOI 10.1073/pnas.0506281103
-
Burd CJ, Petre CE, Morey LM, Wang Y, Revelo MP, Haiman CA, et al. Cyclin D1b variant influences prostate cancer growth through aberrant androgen receptor regulation. Proc Natl Acad Sci USA 2006;103:2190-5. (Pubitemid 43271645)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.7
, pp. 2190-2195
-
-
Burd, C.J.1
Petre, C.E.2
Morey, L.M.3
Wang, Y.4
Revelo, M.P.5
Haiman, C.A.6
Lu, S.7
Fenoglio-Preiser, C.M.8
Li, J.9
Knudsen, E.S.10
Wong, J.11
Knudsen, K.E.12
-
100
-
-
30544449113
-
Impact of cyclin D1 A870G polymorphism in esophageal adenocarcinoma tumorigenesis
-
DOI 10.1053/j.seminoncol.2005.04.023, PII S0093775405001788
-
Izzo JG, Malhotra U, Wu TT, Ensor J, Babenko IM, Swisher SG, et al. Impact of cyclin D1 A870G polymorphism in esophageal adenocarcinoma tumorigenesis. Semin Oncol 2005;32:S11-5. (Pubitemid 43080907)
-
(2005)
Seminars in Oncology
, vol.32
, Issue.SUPPL. 9
-
-
Izzo, J.G.1
Malhotra, U.2
Wu, T.T.3
Ensor, J.4
Babenko, I.M.5
Swisher, S.G.6
Correa, A.7
Bresalier, R.S.8
Hittelman, W.N.9
Ajani, J.A.10
-
101
-
-
29344464892
-
Cyclin D1 gene (CCND1) polymorphism and the risk of squamous cell carcinoma of the larynx
-
DOI 10.1007/s00405-005-0957-7
-
Rydzanicz M, Golusinski P, Mielcarek-Kuchta D, Golusinski W, Szyfter K. Cyclin D1 gene (CCND1) polymorphism and the risk of squamous cell carcinoma of the larynx. Eur Arch Otorhinolaryngol 2006;263:43-8. (Pubitemid 43004710)
-
(2006)
European Archives of Oto-Rhino-Laryngology
, vol.263
, Issue.1
, pp. 43-48
-
-
Rydzanicz, M.1
Golusinski, P.2
Mielcarek-Kuchta, D.3
Golusinski, W.4
Szyfter, K.5
-
102
-
-
3042818713
-
Polymorphism within the cyclin D1 gene is associated with an increased risk of carcinoma in situ in patients with superficial bladder cancer
-
DOI 10.1016/j.urology.2004.03.001, PII S0090429504003164
-
Ito M, Habuchi T, Watanabe J, Higashi S, Nishiyama H, Wang L, et al. Polymorphism within the cyclin D1 gene is associated with an increased risk of carcinoma in situ in patients with superficial bladder cancer. Urology 2004;64:74-8. (Pubitemid 38887582)
-
(2004)
Urology
, vol.64
, Issue.1
, pp. 74-78
-
-
Ito, M.1
Habuchi, T.2
Watanabe, J.3
Higashi, S.4
Nishiyama, H.5
Wang, L.6
Tsuchiya, N.7
Kamoto, T.8
Ogawa, O.9
-
103
-
-
0345098458
-
Association of the Cyclin D1 A870G Polymorphism with Advanced Colorectal Cancer
-
DOI 10.1001/jama.290.21.2843
-
Le Marchand L, Seifried A, Lum-Jones A, Donlon T, Wilkens LR. Association of the cyclin D1 A870G polymorphism with advanced colorectal cancer. Jama 2003;290:2843-8. (Pubitemid 37509493)
-
(2003)
Journal of the American Medical Association
, vol.290
, Issue.21
, pp. 2843-2848
-
-
Le, M.L.1
Seifried, A.2
Lum-Jones, A.3
Donlon, T.4
Wilkens, L.R.5
-
104
-
-
0036154410
-
Polymorphisms in cyclin D1 gene and hepatocellular carcinoma
-
DOI 10.1002/mc.10028
-
Zhang YJ, Chen SY, Chen CJ, Santella RM. Polymorphisms in cyclin D1 gene and hepatocellular carcinoma. Mol Carcinog 2002;33:125-9. (Pubitemid 34113201)
-
(2002)
Molecular Carcinogenesis
, vol.33
, Issue.2
, pp. 125-129
-
-
Zhang, Y.-J.1
Chen, S.-Y.2
Chen, C.-J.3
Santella, R.M.4
-
105
-
-
0031754975
-
Polymorphism within the cyclin D1 gene is associated with prognosis in patients with squamous cell carcinoma of the head and neck
-
Matthias C, Branigan K, Jahnke V, Leder K, Haas J, Heighway J, et al. Polymorphism within the cyclin D1 gene is associated with prognosis in patients with squamous cell carcinoma of the head and neck. Clin Cancer Res 1998;4:2411-8. (Pubitemid 28477906)
-
(1998)
Clinical Cancer Research
, vol.4
, Issue.10
, pp. 2411-2418
-
-
Matthias, C.1
Branigan, K.2
Jahnke, V.3
Leder, K.4
Haas, J.5
Heighway, J.6
Jones, P.W.7
Strange, R.C.8
Fryer, A.A.9
Hoban, P.R.10
-
106
-
-
77952796886
-
Identification of ASF/SF2 as a critical, allele-specific effector of the cyclin D1b oncogene
-
Olshavsky NA, Comstock CE, Schiewer MJ, Augello MA, Hyslop T, Sette C, et al. Identification of ASF/SF2 as a critical, allele-specific effector of the cyclin D1b oncogene. Cancer Res 2010;70:3975-84.
-
(2010)
Cancer Res
, vol.70
, pp. 3975-3984
-
-
Olshavsky, N.A.1
Comstock, C.E.2
Schiewer, M.J.3
Augello, M.A.4
Hyslop, T.5
Sette, C.6
-
107
-
-
75149187424
-
Alternative splicing of the cyclin D1 proto-oncogene is regulated by the RNA-binding protein Sam68
-
Paronetto MP, Cappellari M, Busa R, Pedrotti S, Vitali R, Comstock C, et al. Alternative splicing of the cyclin D1 proto-oncogene is regulated by the RNA-binding protein Sam68. Cancer Res 2010;70:229-39.
-
(2010)
Cancer Res
, vol.70
, pp. 229-239
-
-
Paronetto, M.P.1
Cappellari, M.2
Busa, R.3
Pedrotti, S.4
Vitali, R.5
Comstock, C.6
-
108
-
-
0242526150
-
An Alternatively Spliced Cyclin D1 Isoform, Cyclin D1b, Is a Nuclear Oncogene
-
Lu F, Gladden AB, Diehl JA. An alternatively spliced cyclin D1 isoform, cyclin D1b, is a nuclear oncogene. Cancer Res 2003;63:7056-61. (Pubitemid 37413439)
-
(2003)
Cancer Research
, vol.63
, Issue.21
, pp. 7056-7061
-
-
Lu, F.1
Gladden, A.B.2
Diehl, J.A.3
-
109
-
-
0041528506
-
Cyclin D1 splice variants: Differential effects on localization, RB phosphorylation, and cellular transformation
-
DOI 10.1074/jbc.M303969200
-
Solomon DA, Wang Y, Fox SR, Lambeck TC, Giesting S, Lan Z, et al. Cyclin D1 splice variants. Differential effects on localization, RB phosphorylation, and cellular transformation. J Biol Chem 2003;278:30339-47. (Pubitemid 36962428)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.32
, pp. 30339-30347
-
-
Solomon, D.A.1
Wang, Y.2
Fox, S.R.3
Lambeck, T.C.4
Giesting, S.5
Lan, Z.6
Senderowicz, A.M.7
Knudsen, E.S.8
-
110
-
-
0034616913
-
Distinct initiation and maintenance mechanisms cooperate to induce G1 cell cycle arrest in response to DNA damage
-
Agami R, Bernards R. Distinct initiation and maintenance mechanisms cooperate to induce G1 cell cycle arrest in response to DNA damage. Cell 2000;102:55-66.
-
(2000)
Cell
, vol.102
, pp. 55-66
-
-
Agami, R.1
Bernards, R.2
-
111
-
-
0034238115
-
Down-regulation of p21(WAF1/CIP1) or p27(Kip1) abrogates antiestrogen-mediated cell cycle arrest in human breast cancer cells
-
DOI 10.1073/pnas.160016897
-
Cariou S, Donovan JC, Flanagan WM, Milic A, Bhattacharya N, Slingerland JM. Down-regulation of p21WAF1/CIP1 or p27Kip1 abrogates antiestrogen-mediated cell cycle arrest in human breast cancer cells. Proc Natl Acad Sci U S A 2000;97:9042-6. (Pubitemid 30626670)
-
(2000)
Proceedings of the National Academy of Sciences of the United States of America
, vol.97
, Issue.16
, pp. 9042-9046
-
-
Cariou, S.1
Donovan, J.C.H.2
Flanagan, W.M.3
Milic, A.4
Bhattacharya, N.5
Slingerland, J.M.6
-
112
-
-
0035496099
-
Regulation of lymphocyte proliferation and death by flip
-
Thome M, Tschopp J. Regulation of lymphocyte proliferation and death by FLIP. Nat Rev Immunol 2001;1:50-8. (Pubitemid 33741975)
-
(2001)
Nature Reviews Immunology
, vol.1
, Issue.1
, pp. 50-58
-
-
Thome, M.1
Tschopp, J.2
-
113
-
-
33344476184
-
cFLIP regulation of lymphocyte activation and development
-
DOI 10.1038/nri1787
-
Budd RC, Yeh WC, Tschopp J. cFLIP regulation of lymphocyte activation and development. Nat Rev Immunol 2006;6:196-204. (Pubitemid 43290989)
-
(2006)
Nature Reviews Immunology
, vol.6
, Issue.3
, pp. 196-204
-
-
Budd, R.C.1
Yeh, W.-C.2
Tschopp, J.3
-
114
-
-
0035192884
-
FLICE-inhibitory proteins: Regulators of death receptor-mediated apoptosis
-
DOI 10.1128/MCB.21.24.8247-8254.2001
-
Krueger A, Baumann S, Krammer PH, Kirchhoff S. FLICE-inhibitory proteins: regulators of death receptor-mediated apoptosis. Mol Cell Biol 2001;21:8247-54. (Pubitemid 33108586)
-
(2001)
Molecular and Cellular Biology
, vol.21
, Issue.24
, pp. 8247-8254
-
-
Krueger, A.1
Baumann, S.2
Krammer, P.H.3
Kirchhoff, S.4
-
115
-
-
0035827569
-
Cellular FLICE-inhibitory protein splice variants inhibit different steps of caspase-8 activation at the CD95 death-inducing signaling complex
-
Krueger A, Schmitz I, Baumann S, Krammer PH, Kirchhoff S. Cellular FLICE-inhibitory protein splice variants inhibit different steps of caspase-8 activation at the CD95 death-inducing signaling complex. J Biol Chem 2001;276:20633-40.
-
(2001)
J Biol Chem
, vol.276
, pp. 20633-20640
-
-
Krueger, A.1
Schmitz, I.2
Baumann, S.3
Krammer, P.H.4
Kirchhoff, S.5
-
116
-
-
21444446872
-
Selective knockdown of the long variant of cellular FLICE inhibitory protein augments death receptor-mediated caspase-8 activation and apoptosis
-
DOI 10.1074/jbc.M413962200
-
Sharp DA, Lawrence DA, Ashkenazi A. Selective knockdown of the long variant of cellular FLICE inhibitory protein augments death receptor-mediated caspase-8 activation and apoptosis. J Biol Chem 2005;280:19401-9. (Pubitemid 41379648)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.19
, pp. 19401-19409
-
-
Sharp, D.A.1
Lawrence, D.A.2
Ashkenazi, A.3
-
117
-
-
0037099678
-
L is a dual function regulator for caspase-8 activation and CD95-mediated apoptosis
-
DOI 10.1093/emboj/cdf356
-
Chang DW, Xing Z, Pan Y, Algeciras-Schimnich A, Barnhart BC, Yaish-Ohad S, et al. c-FLIP(L) is a dual function regulator for caspase-8 activation and CD95-mediated apoptosis. Embo J 2002;21:3704-14. (Pubitemid 34787044)
-
(2002)
EMBO Journal
, vol.21
, Issue.14
, pp. 3704-3714
-
-
Chang, D.W.1
Xing, Z.2
Pan, Y.3
Algeciras-Schimnich, A.4
Barnhart, B.C.5
Yaish-Ohad, S.6
Peter, M.E.7
Yang, X.8
-
118
-
-
40949149811
-
R, the only murine short FLIP isoform, reveal requirements for DISC recruitment
-
DOI 10.1038/sj.cdd.4402314, PII 4402314, The biology of Hypoxia-inducible factors
-
Ueffing N, Keil E, Freund C, Kuhne R, Schulze-Osthoff K, Schmitz I. Mutational analyses of c-FLIPR, the only murine short FLIP isoform, reveal requirements for DISC recruitment. Cell Death Differ 2008;15:773-82. (Pubitemid 351405082)
-
(2008)
Cell Death and Differentiation
, vol.15
, Issue.4
, pp. 773-782
-
-
Ueffing, N.1
Keil, E.2
Freund, C.3
Kuhne, R.4
Schulze-Osthoff, K.5
Schmitz, I.6
-
119
-
-
17644378775
-
R, a new regulator of death receptor-induced apoptosis
-
DOI 10.1074/jbc.M414425200
-
Golks A, Brenner D, Fritsch C, Krammer PH. Lavrik IN. c-FLIPR, a new regulator of death receptor-induced apoptosis. J Biol Chem 2005;280:14507-13. (Pubitemid 40562792)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.15
, pp. 14507-14513
-
-
Golks, A.1
Brenner, D.2
Fritsch, C.3
Krammer, P.H.4
Lavrik, I.N.5
-
120
-
-
23744487497
-
Cellular FLICE-inhibitory protein is required for T cell survival and cycling
-
DOI 10.1084/jem.20050118
-
Chau H, Wong V, Chen NJ, Huang HL, Lin WJ, Mirtsos C, et al. Cellular FLICE-inhibitory protein is required for T cell survival and cycling. J Exp Med 2005;202:405-13. (Pubitemid 41126958)
-
(2005)
Journal of Experimental Medicine
, vol.202
, Issue.3
, pp. 405-413
-
-
Chau, H.1
Wong, V.2
Chen, N.-J.3
Huang, H.-L.4
Lin, W.-J.5
Mirtsos, C.6
Elford, A.R.7
Bonnard, M.8
Wakeham, A.9
You-Ten, A.I.10
Lemmers, B.11
Salmena, L.12
Pellegrini, M.13
Hakem, R.14
Mak, T.W.15
Ohashi, P.16
Yeh, W.-C.17
-
121
-
-
23744456144
-
An essential role for c-FLIP in the efficient development of mature T lymphocytes
-
DOI 10.1084/jem.20050117
-
Zhang N, He YW. An essential role for c-FLIP in the efficient development of mature T lymphocytes. J Exp Med 2005;202:395-404. (Pubitemid 41126957)
-
(2005)
Journal of Experimental Medicine
, vol.202
, Issue.3
, pp. 395-404
-
-
Zhang, N.1
He, Y.-W.2
-
122
-
-
0038373452
-
cFLIP-L inhibits p38 MAPK activation. An additional anti-apoptotic mechanism in bile acid-mediated apoptosis
-
DOI 10.1074/jbc.M303229200
-
Grambihler A, Higuchi H, Bronk SF, Gores GJ. cFLIP-L inhibits p38 MAPK activation: an additional anti-apoptotic mechanism in bile acid-mediated apoptosis. J Biol Chem 2003;278:26831-7. (Pubitemid 36876833)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.29
, pp. 26831-26837
-
-
Grambihler, A.1
Higuchi, H.2
Bronk, S.F.3
Gores, G.J.4
-
123
-
-
3543096349
-
NFkappaB activation by Fas is mediated through FADD, caspase-8, and RIP and is inhibited by FLIP
-
DOI 10.1083/jcb.200401036
-
Kreuz S, Siegmund D, Rumpf JJ, Samel D, Leverkus M, Janssen O, et al. NFkappaB activation by Fas is mediated through FADD, caspase-8, and RIP and is inhibited by FLIP. J Cell Biol 2004;166:369-80. (Pubitemid 39031240)
-
(2004)
Journal of Cell Biology
, vol.166
, Issue.3
, pp. 369-380
-
-
Kreuz, S.1
Siegmund, D.2
Rumpf, J.-J.3
Samel, D.4
Leverkus, M.5
Janssen, O.6
Hacker, G.7
Dittrich-Breiholz, O.8
Kracht, M.9
Scheurich, P.10
Wajant, H.11
-
124
-
-
0036310708
-
L modulates T-cell receptor-induced proliferation but not activation-induced cell death of lymphocytes
-
DOI 10.1128/MCB.22.15.5419-5433.2002
-
Lens SM, Kataoka T, Fortner KA, Tinel A, Ferrero I, MacDonald RH, et al. The caspase 8 inhibitor c-FLIP(L) modulates T-cell receptor-induced proliferation but not activation-induced cell death of lymphocytes. Mol Cell Biol 2002;22:5419-33. (Pubitemid 34755753)
-
(2002)
Molecular and Cellular Biology
, vol.22
, Issue.15
, pp. 5419-5433
-
-
Lens, S.M.A.1
Kataoka, T.2
Fortner, K.A.3
Tinel, A.4
Ferrero, I.5
MacDonald, R.H.6
Hahne, M.7
Beermann, F.8
Attinger, A.9
Orbea, H.-A.10
Budd, R.C.11
Tschopp, J.12
-
125
-
-
17844361968
-
+ T cell activation through caspase-8-dependent NF-kappaB activation
-
Dohrman A, Kataoka T, Cuenin S, Russell JQ, Tschopp J, Budd RC. Cellular FLIP (long form) regulates CD8+ T cell activation through caspase-8-dependent NF-kappa B activation. J Immunol 2005;174:5270-8. (Pubitemid 40593165)
-
(2005)
Journal of Immunology
, vol.174
, Issue.9
, pp. 5270-5278
-
-
Dohrman, A.1
Kataoka, T.2
Cuenin, S.3
Russell, J.Q.4
Tschopp, J.5
Budd, R.C.6
-
126
-
-
77955465116
-
Model-based dissection of CD95 signaling dynamics reveals both a pro- And antiapoptotic role of c-FLIPL
-
Fricker N, Beaudouin J, Richter P, Eils R, Krammer PH, Lavrik IN. Model-based dissection of CD95 signaling dynamics reveals both a pro- and antiapoptotic role of c-FLIPL. J Cell Biol 2010;190:377-89.
-
(2010)
J Cell Biol
, vol.190
, pp. 377-389
-
-
Fricker, N.1
Beaudouin, J.2
Richter, P.3
Eils, R.4
Krammer, P.H.5
Lavrik, I.N.6
-
127
-
-
18744425429
-
The caspase-8 inhibitor FLIP promotes activation of NF-kappaB and Erk signaling pathways
-
DOI 10.1016/S0960-9822(00)00512-1
-
Kataoka T, Budd RC, Holler N, Thome M, Martinon F, Irmler M, et al. The caspase-8 inhibitor FLIP promotes activation of NF-kappaB and Erk signaling pathways. Curr Biol 2000;10:640-8. (Pubitemid 30354699)
-
(2000)
Current Biology
, vol.10
, Issue.11
, pp. 640-648
-
-
Kataoka, T.1
Budd, R.C.2
Holler, N.3
Thome, M.4
Martinon, F.5
Irmler, M.6
Burns, K.7
Hahne, M.8
Kennedy, N.9
Kovacsovics, M.10
Tschopp, J.11
-
128
-
-
33144488766
-
Increased expression of cFLIP(L) in colonic adenocarcinoma
-
Ryu BK, Lee MG, Chi SG, Kim YW, Park JH. Increased expression of cFLIP(L) in colonic adenocarcinoma. J Pathol 2001;194:15-9.
-
(2001)
J Pathol
, vol.194
, pp. 15-19
-
-
Ryu, B.K.1
Lee, M.G.2
Chi, S.G.3
Kim, Y.W.4
Park, J.H.5
-
129
-
-
0038387494
-
5-Fluorouracil: Mechanisms of action and clinical strategies
-
DOI 10.1038/nrc1074
-
Longley DB, Harkin DP, Johnston PG. 5-fluorouracil: mechanisms of action and clinical strategies. Nat Rev Cancer 2003;3:330-8. (Pubitemid 37328853)
-
(2003)
Nature Reviews Cancer
, vol.3
, Issue.5
, pp. 330-338
-
-
Longley, D.B.1
Harkin, D.P.2
Johnston, P.G.3
-
130
-
-
0034712536
-
Irinotecan combined with fluorouracil compared with fluorouracil alone. As first-line treatment for metastatic colorectal cancer: A multicentre randomised trial
-
Douillard JY, Cunningham D, Roth AD, Navarro M, James RD, Karasek P, et al. Irinotecan combined with fluorouracil compared with fluorouracil alone as first-line treatment for metastatic colorectal cancer: a multicentre randomised trial. Lancet 2000;355:1041-7. (Pubitemid 30162806)
-
(2000)
Lancet
, vol.355
, Issue.9209
, pp. 1041-1047
-
-
Douillard, J.Y.1
Cunningham, D.2
Roth, A.D.3
Navarro, M.4
James, R.D.5
Karasek, P.6
Jandik, P.7
Iveson, T.8
Carmichael, J.9
Alakl, M.10
Gruia, G.11
Awad, L.12
Rougier, P.13
-
131
-
-
0033989203
-
Phase III multicenter randomized trial of oxaliplatin added to chronomodulated fluorouracil-leucovorin as first-line treatment of metastatic colorectal cancer
-
Giacchetti S, Perpoint B, Zidani R, Le Bail N, Faggiuolo R, Focan C, et al. Phase III multicenter randomized trial of oxaliplatin added to chronomodulated fluorouracil-leucovorin as first-line treatment of metastatic colorectal cancer. J Clin Oncol 2000;18:136-47. (Pubitemid 30036347)
-
(2000)
Journal of Clinical Oncology
, vol.18
, Issue.1
, pp. 136-147
-
-
Giacchetti, S.1
Perpoint, B.2
Zidani, R.3
Le, B.N.4
Faggiuolo, R.5
Focan, C.6
Chollet, P.7
Llory, J.F.8
Letourneau, Y.9
Coudert, B.10
Bertheaut-Cvitkovic, F.11
Larregain-Fournier, D.12
Le, R.A.13
Walter, S.14
Adam, R.15
Misset, J.L.16
Levi, F.17
-
132
-
-
65649089859
-
5-Fluorouracil and its active metabolite FdUMP cause DNA damage in human SW620 colon adenocarcinoma cell line
-
Matuo R, Sousa FG, Escargueil AE, Grivicich I, Garcia-Santos D, Chies JA, et al. 5-Fluorouracil and its active metabolite FdUMP cause DNA damage in human SW620 colon adenocarcinoma cell line. J Appl Toxicol 2009;29:308-16.
-
(2009)
J Appl Toxicol
, vol.29
, pp. 308-316
-
-
Matuo, R.1
Sousa, F.G.2
Escargueil, A.E.3
Grivicich, I.4
Garcia-Santos, D.5
Chies, J.A.6
-
133
-
-
32544438637
-
c-FLIP inhibits chemotherapy-induced colorectal cancer cell death
-
DOI 10.1038/sj.onc.1209122, PII 1209122
-
Longley DB, Wilson TR, McEwan M, Allen WL, McDermott U, Galligan L, et al. c-FLIP inhibits chemotherapy-induced colorectal cancer cell death. Oncogene 2006;25:838-48. (Pubitemid 43237702)
-
(2006)
Oncogene
, vol.25
, Issue.6
, pp. 838-848
-
-
Longley, D.B.1
Wilson, T.R.2
McEwan, M.3
Allen, W.L.4
McDermott, U.5
Galligan, L.6
Johnston, P.G.7
-
134
-
-
34250844497
-
c-FLIP: A key regulator of colorectal cancer cell death
-
DOI 10.1158/0008-5472.CAN-06-3585
-
Wilson TR, McLaughlin KM, McEwan M, Sakai H, Rogers KM, Redmond KM, et al. c-FLIP: a key regulator of colorectal cancer cell death. Cancer Res 2007;67:5754-62. (Pubitemid 46985008)
-
(2007)
Cancer Research
, vol.67
, Issue.12
, pp. 5754-5762
-
-
Wilson, T.R.1
McLaughlin, K.M.2
McEwan, M.3
Sakai, H.4
Rogers, K.M.A.5
Redmond, K.M.6
Johnston, P.G.7
Longley, D.B.8
-
135
-
-
33847390640
-
One, two, three-p53, p63, p73 and chemosensitivity
-
Muller M, Schleithoff ES, Stremmel W, Melino G, Krammer PH, Schilling T. One, two, three-p53, p63, p73 and chemosensitivity. Drug Resist Updat 2006;9:288-306.
-
(2006)
Drug Resist Updat
, vol.9
, pp. 288-306
-
-
Muller, M.1
Schleithoff, E.S.2
Stremmel, W.3
Melino, G.4
Krammer, P.H.5
Schilling, T.6
-
136
-
-
4644299291
-
Alternative splicing of Bcl-2-related genes: Functional consequences and potential therapeutic applications
-
DOI 10.1007/s00018-004-4001-7
-
Akgul C, Moulding DA, Edwards SW. Alternative splicing of Bcl-2-related genes: functional consequences and potential therapeutic applications. Cell Mol Life Sci 2004;61:2189-99. (Pubitemid 39280118)
-
(2004)
Cellular and Molecular Life Sciences
, vol.61
, Issue.17
, pp. 2189-2199
-
-
Akgul, C.1
Moulding, D.A.2
Edwards, S.W.3
-
137
-
-
0034327411
-
An informatics approach identifying markers of chemosensitivity in human cancer cell lines
-
Amundson SA, Myers TG, Scudiero D, Kitada S, Reed JC, Fornace Jr AJ. An informatics approach identifying markers of chemosensitivity in human cancer cell lines. Cancer Res 2000;60:6101-10.
-
(2000)
Cancer Res
, vol.60
, pp. 6101-6110
-
-
Amundson, S.A.1
Myers, T.G.2
Scudiero, D.3
Kitada, S.4
Reed, J.C.5
Fornace Jr., A.J.6
-
138
-
-
0034682837
-
MCL-1S, a splicing variant of the antiapoptotic BCL-2 family member MCL-1, encodes a proapoptotic protein possessing only the BH3 domain
-
Bae J, Leo CP, Hsu SY, Hsueh AJ. MCL-1S, a splicing variant of the antiapoptotic BCL-2 family member MCL-1, encodes a proapoptotic protein possessing only the BH3 domain. J Biol Chem 2000;275:25255-61.
-
(2000)
J Biol Chem
, vol.275
, pp. 25255-25261
-
-
Bae, J.1
Leo, C.P.2
Hsu, S.Y.3
Hsueh, A.J.4
-
139
-
-
79960282729
-
Modulation of RNA splicing as a potential treatment for cancer
-
Bauman JA, Kole R. Modulation of RNA splicing as a potential treatment for cancer. Bioeng Bugs 2011;2:125-8.
-
(2011)
Bioeng Bugs
, vol.2
, pp. 125-128
-
-
Bauman, J.A.1
Kole, R.2
-
140
-
-
78049416081
-
Alternative pre-mRNA splicing regulation in cancer: Pathways and programs unhinged
-
David CJ, Manley JL. Alternative pre-mRNA splicing regulation in cancer: pathways and programs unhinged. Genes Dev 2010;24:2343-64.
-
(2010)
Genes Dev
, vol.24
, pp. 2343-2364
-
-
David, C.J.1
Manley, J.L.2
|