Splicing regulation at the second catalytic step by Sex-lethal involves 3′ splice site recognition by SPF45

Cell

Volumn 109, Issue 3, 2002, Pages 285-296

  Lallena, María José ^a   Chalmers, Kevin J ^b   Llamazares, Salud ^a   Lamond, Angus I ^b   Valcárcel, Juan ^a  

^a EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

^b UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

M PROTEIN; PROTEIN SPF45; PROTEIN SXL; PYRIMIDINE; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; BETA THALASSEMIA; CATALYSIS; CONTROLLED STUDY; DROSOPHILA; EXON; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; SPLICEOSOME;

DROSOPHILA;

EID: 0037013146     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(02)00730-4     Document Type: Article

References (57)

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3. Positive autoregulation of sex-lethal by alternative splicing maintains the female determined state in Drosophila
4. Analysis of the RNA-recognition motif and RS and RGG domains: Conservation in metazoan pre-mRNA splicing factors
5. Requirement for SLU7 in yeast pre-mRNA splicing is dictated by the distance between the branchpoint and the 3′ splice site
6. Evidence for a linear search in bimolecular 3′ splice site AG selection
7. Evidence that U5 snRNP recognizes the 3′ splice site for catalytic step II in mammals
8. The RNA splicing factor hSlu7 is required for correct 3′ splice site choice
9. Human step II splicing factor hSlu7 functions in restructuring the spliceosome between the catalytic steps of splicing
10. An upstream AG determines whether a downstream AG is selected during catalytic step II of splicing
11. Vive la difference: Males vs females in flies vs worms
12. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei
13. An essential splicing factor, SLU7, mediates 3′ splice site choice in yeast
14. Modulation of msl-2 5′ splice site recognition by Sex-lethal
15. Targeting of U2AF65 to sites of active splicing in the nucleus
16. Polyoma virus small tumor antigen pre-mRNA splicing requires cooperation between two 3′ splice sites
17. The Drosophila splicing regulator sex-lethal directly inhibits translation of male-specific-lethal 2 mRNA
18. A novel set of spliceosome-associated proteins and the essential splicing factor PSF bind stably to pre-mRNA prior to catalytic step II of the splicing reaction
19. Distinct mechanisms of splicing regulation in vivo by the Drosophila protein Sex-lethal
20. Alternative splicing: Increasing diversity in the proteomic world
21. Structural basis for recognition of the tra mRNA precursor by the Sex-lethal protein
22. Pre-mRNA splicing in the new millennium
23. Sex-lethal autoregulation requires multiple cis-acting elements upstream and downstream of the male exon and appears to depend largely on controlling the use of the male exon 5′ splice site
24. Binding of the Drosophila sex-lethal gene product to the alternative splice site of transformer primary transcript
25. Characterization and functional ordering of Slu7p and Prp17p during the second step of pre-mRNA splicing in yeast
26. Expression of msl-2 causes assembly of dosage compensation regulators on the X chromosomes and female lethality in Drosophila
27. Mechanisms of human-globin pre-mRNA splicing
28. The role of branchpoint-3′ splice site spacing and interaction between intron terminal nucleotides in 3′ splice site selection in Saccharomyces cerevisiae
29. 35 and the 3′ splice site AG
30. Intron recognition comes of AGe
31. Site-specific modification of pre-mRNA: The 2'-hydroxyl groups at the splice sites
32. Mass spectrometry and EST-database searching allows characterization of the multi-protein spliceosome complex
33. Switch in 3′ splice site recognition between exon definition and splicing catalysis is important for sex-lethal autoregulation
34. The organization of 3′ splice sequences in mammalian introns
35. Alternative branch points are selected during splicing of a yeast pre-mRNA in mammalian and yeast extracts
36. Control of Drosophila Sex-lethal pre-mRNA splicing by its own female-specific product
37. Alterations of RNase H sensitivity of the 3′ splice site region during the in vitro splicing reaction
38. PRP16 is an RNA-dependent ATPase that interacts transiently with the spliceosome
39. A conformational rearrangement in the spliceosome is dependent on PRP16 and ATP hydrolysis
40. Structure, function and evolution of sex-determining systems in Dipteran insects
41. Alternative pre-mRNA splicing: The logic of combinatorial control
42. Scanning from an independently specified branch point defines the 3′ splice site of mammalian introns
43. Scanning and competition between AGs are involved in 3′ splice site selection in mammalian introns
44. Sex-specific alternative splicing of RNA from the transformer gene results from sequence-dependent splice site blockage
45. 65 and SR proteins in splicing of pre-mRNA
46. The second catalytic step of pre-mRNA splicing
47. Prp16p, Slu7p, and Prp8p interact with the 3′ splice site in two distinct stages during the second catalytic step of pre-mRNA splicing
48. The protein Sex-lethal antagonizes the splicing factor U2AF to regulate alternative splicing of transformer pre-mRNA
49. The Sex-lethal amino terminus mediates cooperative interactions in RNA binding and is essential for splicing regulation
50. Spliceosomal UsnRNP biogenesis, structure and function
51. Identification of a human protein that recognizes the 3′ splice site during the second step of pre-mRNA splicing
52. 35
53. Cloning and domain structure of the mammalian splicing factor U2AF
54. The conserved dinucleotide AG of the 3′ splice site may be recognized twice during in vitro splicing of mammalian mRNA precursors
55. Gel electrophoretic isolation of splicing complexes containing U1 small nuclear ribonucleoprotein particles
56. Both subunits of U2AF recognize the 3′ splice site in Caenorhabditis elegans
57. 35 mediates critical protein-protein interactions in constitutive and enhancer-dependent splicing