Selective knockdown of the long variant of cellular FLICE inhibitory protein augments death receptor-mediated caspase-8 activation and apoptosis

Journal of Biological Chemistry

Volumn 280, Issue 19, 2005, Pages 19401-19409

  Sharp, Darcie A ^a   Lawrence, David A ^a   Ashkenazi, Avi ^a  

^a GENENTECH INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ANALYSIS; CELLS; PROTEINS; RNA; SIGNALING; TUMORS;

APOPTOSIS; LIGANDS; NECROSIS;

ENZYMES;

APOPTOSIS INHIBITOR; CASPASE 10; CASPASE 8; CYSTEINE PROTEINASE; DEATH RECEPTOR; FLICE INHIBITORY PROTEIN; SMALL INTERFERING RNA; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; APOPTOSIS REGULATORY PROTEIN; CASP10 PROTEIN, HUMAN; CASP8 PROTEIN, HUMAN; CASPASE; CFLAR PROTEIN, HUMAN; LIGAND; MEMBRANE PROTEIN; MESSENGER RNA; SIGNAL PEPTIDE; TNFSF10 PROTEIN, HUMAN; TUMOR NECROSIS FACTOR ALPHA;

ALTERNATIVE RNA SPLICING; APOPTOSIS; ARTICLE; CELL DEATH; CONTROLLED STUDY; ENZYME ACTIVATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; INHIBITION KINETICS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN PROCESSING; CELL LINE; DIMERIZATION; DOSE RESPONSE; GENETIC TRANSFECTION; GENETICS; HELA CELL; IMMUNOBLOTTING; IMMUNOPRECIPITATION; METABOLISM; PHYSIOLOGY; TIME; TUMOR CELL LINE;

ALTERNATIVE SPLICING; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CASP8 AND FADD-LIKE APOPTOSIS REGULATING PROTEIN; CASPASE 10; CASPASE 8; CASPASES; CELL LINE; CELL LINE, TUMOR; DIMERIZATION; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; HELA CELLS; HUMANS; IMMUNOBLOTTING; IMMUNOPRECIPITATION; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LIGANDS; MEMBRANE GLYCOPROTEINS; RNA, MESSENGER; RNA, SMALL INTERFERING; TIME FACTORS; TNF-RELATED APOPTOSIS-INDUCING LIGAND; TRANSFECTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 21444446872     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M413962200     Document Type: Article

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