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Volumn 15, Issue 2, 1996, Pages 265-275

The Clk/Sty protein kinase phosphorylates SR splicing factors and regulates their intranuclear distribution

Author keywords

ASF; Protein phosphorylation; RS domains; SF2

Indexed keywords

ARGININE; NUCLEAR PROTEIN; PHOSPHOTRANSFERASE; PROTEIN KINASE; RNA BINDING PROTEIN; SERINE; SPLICING FACTOR; UNCLASSIFIED DRUG;

EID: 0030028882     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1002/j.1460-2075.1996.tb00357.x     Document Type: Article
Times cited : (488)

References (68)
  • 1
    • 0028324929 scopus 로고
    • The role of specific protein-RNA and protein-protein interactions in positive and negative control of pre-mRNA splicing by Transformer 2
    • Amrein, H., Hedley, M.L. and Maniatis, T. (1994) The role of specific protein-RNA and protein-protein interactions in positive and negative control of pre-mRNA splicing by Transformer 2 Cell, 76, 735-746.
    • (1994) Cell , vol.76 , pp. 735-746
    • Amrein, H.1    Hedley, M.L.2    Maniatis, T.3
  • 2
    • 0026021433 scopus 로고
    • A differentially expressed murine RNA encoding a protein with similarities to two types of nucleic acid binding motifs
    • Ayane, M., Preuss, U., Kohler, G. and Nielsen, P.J. (1991) A differentially expressed murine RNA encoding a protein with similarities to two types of nucleic acid binding motifs. Nucleic Acids Res., 19, 1273-1278
    • (1991) Nucleic Acids Res. , vol.19 , pp. 1273-1278
    • Ayane, M.1    Preuss, U.2    Kohler, G.3    Nielsen, P.J.4
  • 3
    • 0026011116 scopus 로고
    • A mammalian protein kinase with potential for serine/threonine and tyrosine phosphorylation is related to cell cycle regulators
    • Ben-David, Y., Letwin, K., Tannock, L., Bernstein, A and Pawson, T. (1991) A mammalian protein kinase with potential for serine/threonine and tyrosine phosphorylation is related to cell cycle regulators. EMBO J., 10, 317-325.
    • (1991) EMBO J. , vol.10 , pp. 317-325
    • Ben-David, Y.1    Letwin, K.2    Tannock, L.3    Bernstein, A.4    Pawson, T.5
  • 4
    • 0028091660 scopus 로고
    • AFCI, a LAMMER kinase from Arabidopsis thaliana, activates STE12-dependent processes in yeast
    • Bender, J. and Fink, G.R. (1994) AFCI, a LAMMER kinase from Arabidopsis thaliana, activates STE12-dependent processes in yeast Proc. Natl Acad Sci USA, 91, 12105-12109.
    • (1994) Proc. Natl Acad Sci USA , vol.91 , pp. 12105-12109
    • Bender, J.1    Fink, G.R.2
  • 5
    • 0025998840 scopus 로고
    • Phosphopeptide mapping and phosphoamino acid analysis by two-dimensional separation on thin-layer cellulose plates
    • Boyle, W.J., van der Geer, P. and Hunter, T. (1991) Phosphopeptide mapping and phosphoamino acid analysis by two-dimensional separation on thin-layer cellulose plates. Methods Enzymol., 201, 110-149.
    • (1991) Methods Enzymol. , vol.201 , pp. 110-149
    • Boyle, W.J.1    Van Der Geer, P.2    Hunter, T.3
  • 6
    • 0028129989 scopus 로고
    • Conserved structures and diversity of functions of RNA-binding proteins
    • Burd, C.G. and Dreyfuss, G. (1994) Conserved structures and diversity of functions of RNA-binding proteins. Science, 265, 615-621.
    • (1994) Science , vol.265 , pp. 615-621
    • Burd, C.G.1    Dreyfuss, G.2
  • 7
    • 0027501327 scopus 로고
    • Functional analysis of pre-mRNA splicing factor SF2/ASF structural domains
    • Caceres, J.F. and Krainer, A.R. (1993) Functional analysis of pre-mRNA splicing factor SF2/ASF structural domains. EMBO J., 12, 4715-4726.
    • (1993) EMBO J. , vol.12 , pp. 4715-4726
    • Caceres, J.F.1    Krainer, A.R.2
  • 8
    • 0027998643 scopus 로고
    • Protein phosphatase 1 can modulate alternative 5′ splice site selection in a HeLa splicing extract
    • Cardinali, B., Cohen, P.T.W. and Lamond, A.I. (1994) Protein phosphatase 1 can modulate alternative 5′ splice site selection in a HeLa splicing extract FEBS Lett., 352, 276-280.
    • (1994) FEBS Lett. , vol.352 , pp. 276-280
    • Cardinali, B.1    Cohen, P.T.W.2    Lamond, A.I.3
  • 13
    • 0022340978 scopus 로고
    • Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product
    • Evan, G.I., Lewis, G.K., Ramsay, G. and Bishop, J.M. (1985) Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product. Mol. Cell. Biol., 5, 3610-3616.
    • (1985) Mol. Cell. Biol. , vol.5 , pp. 3610-3616
    • Evan, G.I.1    Lewis, G.K.2    Ramsay, G.3    Bishop, J.M.4
  • 14
    • 0021334795 scopus 로고
    • Ultrastructural distribution of nuclear ribonucleoproteins as visualized by immunocytochemistry on thin sections
    • Fakan, S , Leser, G. and Martin, T.E. (1984) Ultrastructural distribution of nuclear ribonucleoproteins as visualized by immunocytochemistry on thin sections. J. Cell Biol., 98, 358-363.
    • (1984) J. Cell Biol. , vol.98 , pp. 358-363
    • Fakan, S.1    Leser, G.2    Martin, T.E.3
  • 15
    • 0024406857 scopus 로고
    • A novel genetic system to detect protein-protein interactions
    • Fields, S. and Song, O.-K. (1989) A novel genetic system to detect protein-protein interactions. Nature, 340, 245-246.
    • (1989) Nature , vol.340 , pp. 245-246
    • Fields, S.1    Song, O.-K.2
  • 16
    • 0027424442 scopus 로고
    • Specific commitment of different pre-mRNAs to splicing by single SR proteins
    • Fu, X.-D. (1993) Specific commitment of different pre-mRNAs to splicing by single SR proteins. Nature, 365, 82-85.
    • (1993) Nature , vol.365 , pp. 82-85
    • Fu, X.-D.1
  • 17
    • 0025115231 scopus 로고
    • Factor required for mammalian spliceosome assembly is localized to discrete regions in the nucleus
    • Fu, X.-D. and Maniatis, T. (1990) Factor required for mammalian spliceosome assembly is localized to discrete regions in the nucleus. Nature, 343, 437-441.
    • (1990) Nature , vol.343 , pp. 437-441
    • Fu, X.-D.1    Maniatis, T.2
  • 18
    • 0025324948 scopus 로고
    • A protein factor, ASF, controls cell-specific alternative splicing of SV40 early pre-mRNA in vitro
    • Ge, H. and Manley, J.L. (1990) A protein factor, ASF, controls cell-specific alternative splicing of SV40 early pre-mRNA in vitro. Cell, 62, 25-34.
    • (1990) Cell , vol.62 , pp. 25-34
    • Ge, H.1    Manley, J.L.2
  • 19
    • 0025827463 scopus 로고
    • Primary structure of the human splicing factor ASF reveals similarities with Drosophila regulators
    • Ge, H , Zuo, P. and Manley, J.L. (1991) Primary structure of the human splicing factor ASF reveals similarities with Drosophila regulators. Cell, 66, 373-382.
    • (1991) Cell , vol.66 , pp. 373-382
    • Ge, H.1    Zuo, P.2    Manley, J.L.3
  • 21
    • 0028286596 scopus 로고
    • A senne kinase regulates intracellular localization of splicing factors in the cell cycle
    • Gui, J.-F., Lane, W.S. and Fu, X.-D. (1994a) A senne kinase regulates intracellular localization of splicing factors in the cell cycle. Nature, 369, 678-682.
    • (1994) Nature , vol.369 , pp. 678-682
    • Gui, J.-F.1    Lane, W.S.2    Fu, X.-D.3
  • 22
    • 0027962510 scopus 로고
    • Purification and characterization of a kinase specific for the serine- and arginine-rich pre-mRNA splicing factors
    • Gui, J.-F., Tronchere, H., Chandler, S.D. and Fu, X -D. (1994b) Purification and characterization of a kinase specific for the serine- and arginine-rich pre-mRNA splicing factors. Proc. Natl Acad. Sci. USA, 91, 10824-10828.
    • (1994) Proc. Natl Acad. Sci. USA , vol.91 , pp. 10824-10828
    • Gui, J.-F.1    Tronchere, H.2    Chandler, S.D.3    Fu, X.D.4
  • 23
    • 0027938872 scopus 로고
    • Characterization by cDNA cloning of two new human protein kinases
    • Hanes, J., von der Kammer, H , Klaudiny, J. and Scheit, K.H (1994) Characterization by cDNA cloning of two new human protein kinases. J. Mol. Biol., 244, 665-672.
    • (1994) J. Mol. Biol. , vol.244 , pp. 665-672
    • Hanes, J.1    Von Der Kammer, H.2    Klaudiny, J.3    Scheit, K.H.4
  • 24
    • 0023885305 scopus 로고
    • The protein kinase family: Conserved features and deduced phylogeny of the catalytic domains
    • Hanks, S.K., Quinn, A.M. and Hunter, T. (1988) The protein kinase family: conserved features and deduced phylogeny of the catalytic domains. Science, 241, 42-52.
    • (1988) Science , vol.241 , pp. 42-52
    • Hanks, S.K.1    Quinn, A.M.2    Hunter, T.3
  • 25
    • 0026345394 scopus 로고
    • Protein kinase catalytic domain sequence database: Identification of conserved features of primary structure and classification of family members
    • Hanks, S.K., Quinn, A.M and Hunter, T. (1991) Protein kinase catalytic domain sequence database: identification of conserved features of primary structure and classification of family members. Methods Enzymol., 200, 38-62.
    • (1991) Methods Enzymol. , vol.200 , pp. 38-62
    • Hanks, S.K.1    Quinn, A.M.2    Hunter, T.3
  • 27
    • 0027496935 scopus 로고
    • The p21 CDK-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases
    • Harper, J.W., Adami, G.R., Wei, N , Keyomarsi, K. and Elledge, S.J. (1993) The p21 CDK-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases. Cell, 75, 805-816.
    • (1993) Cell , vol.75 , pp. 805-816
    • Harper, J.W.1    Adami, G.R.2    Wei, N.3    Keyomarsi, K.4    Elledge, S.J.5
  • 30
    • 0025756794 scopus 로고
    • Molecular cloning of a novel human cdc2/CDC28-like protein kinase
    • Johnson, K.W. and Smith, K.A. (1991) Molecular cloning of a novel human cdc2/CDC28-like protein kinase. J. Biol. Chem., 266, 3402-3407.
    • (1991) J. Biol. Chem. , vol.266 , pp. 3402-3407
    • Johnson, K.W.1    Smith, K.A.2
  • 31
    • 0025761656 scopus 로고
    • RNA recognition: Towards identifying determinants of specificity
    • Kenan, D J., Query, C.C. and Keene, J.D (1991) RNA recognition: towards identifying determinants of specificity. Trends Biochem. Sci , 16, 214-220.
    • (1991) Trends Biochem. Sci , vol.16 , pp. 214-220
    • Kenan, D.J.1    Query, C.C.2    Keene, J.D.3
  • 32
    • 0026326821 scopus 로고
    • Structure of a peptide inhibitor bound to the catalytic subunit of cyclic adenosine monophosphate-dependent protein kinase
    • Knighton, D.R., Zheng, J., Ten Eyck, L.F., Xuong, N.-H., Taylor, S.S. and Sadowski, J.M. (1991) Structure of a peptide inhibitor bound to the catalytic subunit of cyclic adenosine monophosphate-dependent protein kinase. Science, 253, 414-424.
    • (1991) Science , vol.253 , pp. 414-424
    • Knighton, D.R.1    Zheng, J.2    Ten Eyck, L.F.3    Xuong, N.-H.4    Taylor, S.S.5    Sadowski, J.M.6
  • 34
    • 0025367075 scopus 로고
    • The essential pre-mRNA splicing factor SF2 influences 5′ splice site selection by activating proximal sites
    • Krainer, A.R., Conway, G.C. and Kozak, D. (1990) The essential pre-mRNA splicing factor SF2 influences 5′ splice site selection by activating proximal sites Cell, 62, 35-42.
    • (1990) Cell , vol.62 , pp. 35-42
    • Krainer, A.R.1    Conway, G.C.2    Kozak, D.3
  • 35
    • 0025743575 scopus 로고
    • Functional expression of cloned human splicing factor SF2: Homology to RNA-binding proteins, U1 70K, and Drosophila regulators
    • Krainer, A.R., Mayeda, A., Kozak, D. and Binns, G. (1991) Functional expression of cloned human splicing factor SF2: homology to RNA-binding proteins, U1 70K, and Drosophila regulators Cell, 66, 383-394
    • (1991) Cell , vol.66 , pp. 383-394
    • Krainer, A.R.1    Mayeda, A.2    Kozak, D.3    Binns, G.4
  • 36
    • 0026058877 scopus 로고
    • a) and tra RNA processing regulators target proteins to a subnuclear compartment implicated in splicing
    • a) and tra RNA processing regulators target proteins to a subnuclear compartment implicated in splicing. Cell, 67, 335-342.
    • (1991) Cell , vol.67 , pp. 335-342
    • Li, H.1    Bingham, P.M.2
  • 37
    • 0026555495 scopus 로고
    • Dual-specificity protein kinases: Will any hydroxyl do?
    • Lindberg, R.A , Quinn, A.M. and Hunter, T. (1992) Dual-specificity protein kinases: will any hydroxyl do? Trends Biochem. Sci., 17, 114-119.
    • (1992) Trends Biochem. Sci. , vol.17 , pp. 114-119
    • Lindberg, R.A.1    Quinn, A.M.2    Hunter, T.3
  • 38
    • 0026731973 scopus 로고
    • Ser/Thr-specific protein phosphatases are required for both catalytic steps of pre-mRNA splicing
    • Mermoud, J E., Cohen, P. and Lamond, A.I. (1992) Ser/Thr-specific protein phosphatases are required for both catalytic steps of pre-mRNA splicing. Nucleic Acids Res., 20, 5263-5269.
    • (1992) Nucleic Acids Res. , vol.20 , pp. 5263-5269
    • Mermoud, J.E.1    Cohen, P.2    Lamond, A.I.3
  • 39
    • 0028043718 scopus 로고
    • Regulation of mammalian spliceosome assembly by a protein phosphorylation mechanism
    • Mermoud, J.E , Cohen, P.T W and Lamond, A.I. (1994) Regulation of mammalian spliceosome assembly by a protein phosphorylation mechanism. EMBO J , 13, 5679-5688.
    • (1994) EMBO J , vol.13 , pp. 5679-5688
    • Mermoud, J.E.1    Cohen, P.T.W.2    Lamond, A.I.3
  • 40
    • 0027939858 scopus 로고
    • The dual-specificity CLK kinase induces neuronal differentiation of PC12 cells
    • Myers, M.P., Murphy, M.B. and Landreth, G. (1994) The dual-specificity CLK kinase induces neuronal differentiation of PC12 cells. Mol. Cell. Biol., 14, 6954-6961
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 6954-6961
    • Myers, M.P.1    Murphy, M.B.2    Landreth, G.3
  • 41
    • 0025815514 scopus 로고
    • The KNS1 gene of Saccharomyces cerevisiae encodes a nonessential protein kinase homologue that is distantly related to members of the CDC28/cdc2 gene family
    • Padmanabha, R., Gehrung, S. and Snyder, M (1991) The KNS1 gene of Saccharomyces cerevisiae encodes a nonessential protein kinase homologue that is distantly related to members of the CDC28/cdc2 gene family. Mol Gen. Genet , 229, 1-9.
    • (1991) Mol Gen. Genet , vol.229 , pp. 1-9
    • Padmanabha, R.1    Gehrung, S.2    Snyder, M.3
  • 42
    • 0026355413 scopus 로고
    • Protein kinase phosphorylation site sequences and consensus specificity motifs, tabulations
    • Pearson, R.B. and Kemp, B.E. (1991) Protein kinase phosphorylation site sequences and consensus specificity motifs, tabulations. Methods Enzymol., 200, 62-81.
    • (1991) Methods Enzymol. , vol.200 , pp. 62-81
    • Pearson, R.B.1    Kemp, B.E.2
  • 43
    • 0024633240 scopus 로고
    • A dosage-sensitive modifier of retrotransposon induced alleles of the Drosophila white locus
    • Rabinow, L. and Birchler, J.A. (1989) A dosage-sensitive modifier of retrotransposon induced alleles of the Drosophila white locus. EMBO J , 8, 879-889.
    • (1989) EMBO J , vol.8 , pp. 879-889
    • Rabinow, L.1    Birchler, J.A.2
  • 44
    • 0025812785 scopus 로고
    • Signal transduction by normal isoforms and W mutant variants of the Kit receptor tyrosine kinase
    • Reith, A.D., Ellis, C., Lyman, S.D , Anderson, D.M , Williams, D.E , Bernstein, A. and Pawson, T. (1991) Signal transduction by normal isoforms and W mutant variants of the Kit receptor tyrosine kinase. EMBO J , 10, 2451-2459.
    • (1991) EMBO J , vol.10 , pp. 2451-2459
    • Reith, A.D.1    Ellis, C.2    Lyman, S.D.3    Anderson, D.M.4    Williams, D.E.5    Bernstein, A.6    Pawson, T.7
  • 45
    • 0029027778 scopus 로고
    • Overexpression of the arginine-rich carboxy-terminal region of U1 snRNP 70K inhibits both splicing and nucleocytoplasmic transport of mRNA
    • Romac, J.M J. and Keene, J D. (1995) Overexpression of the arginine-rich carboxy-terminal region of U1 snRNP 70K inhibits both splicing and nucleocytoplasmic transport of mRNA. Genes Dev., 9, 1400-1410.
    • (1995) Genes Dev. , vol.9 , pp. 1400-1410
    • Romac, J.M.J.1    Keene, J.D.2
  • 46
    • 0025689134 scopus 로고
    • A monoclonal antibody that recognizes a phosphorylated epitope stains lampbrush chromosome loops and small granules in the amphibian germinal vesicle
    • Roth, M B., Murphy, C. and Gall, J.G. (1990) A monoclonal antibody that recognizes a phosphorylated epitope stains lampbrush chromosome loops and small granules in the amphibian germinal vesicle. J. Cell Biol., 111, 2217-2223.
    • (1990) J. Cell Biol. , vol.111 , pp. 2217-2223
    • Roth, M.B.1    Murphy, C.2    Gall, J.G.3
  • 47
    • 0023627442 scopus 로고
    • gag-fps protein-tyrosine kinase distinguished by the expression of v-fps polypeptides in Escherichia coli
    • gag-fps protein-tyrosine kinase distinguished by the expression of v-fps polypeptides in Escherichia coli. Oncogene, 1, 181-191
    • (1987) Oncogene , vol.1 , pp. 181-191
    • Sadowski, I.1    Pawson, T.2
  • 48
    • 0027488050 scopus 로고
    • Sequence of a complete murine cDNA reflecting an S phase-prevalent transcript encoding a protein with two types of nucleic acid binding motifs
    • Schmidt, G. and Werner, D. (1993) Sequence of a complete murine cDNA reflecting an S phase-prevalent transcript encoding a protein with two types of nucleic acid binding motifs. Biochim. Biophys. Acta, 1216, 317-320
    • (1993) Biochim. Biophys. Acta , vol.1216 , pp. 317-320
    • Schmidt, G.1    Werner, D.2
  • 50
    • 0027317070 scopus 로고
    • hnRNP G: Sequence and characterization of a glycosylated RNA-binding protein
    • Soulard, M. et al. (1993) hnRNP G: sequence and characterization of a glycosylated RNA-binding protein. Nucleic Acids Res., 21, 4210-4217.
    • (1993) Nucleic Acids Res. , vol.21 , pp. 4210-4217
    • Soulard, M.1
  • 51
    • 0027135889 scopus 로고
    • Macromolecular domains within the cell nucleus
    • Spector, D.L. (1993) Macromolecular domains within the cell nucleus. Annu. Rev. Cell Biol , 9, 265-315.
    • (1993) Annu. Rev. Cell Biol , vol.9 , pp. 265-315
    • Spector, D.L.1
  • 52
    • 0021082681 scopus 로고
    • Immunoelectron microscopic localization of snRNPs
    • Spector, D.L., Schrier, W.H. and Busch, H. (1983) Immunoelectron microscopic localization of snRNPs. Biol. Cell., 49, 1-10.
    • (1983) Biol. Cell. , vol.49 , pp. 1-10
    • Spector, D.L.1    Schrier, W.H.2    Busch, H.3
  • 53
    • 0026665436 scopus 로고
    • ASF alternative transcripts are highly conserved between mouse and man
    • Tacke, R , Boned, A. and Goridis, C. (1992) ASF alternative transcripts are highly conserved between mouse and man. Nucleic Acids Res., 20, 5482.
    • (1992) Nucleic Acids Res. , vol.20 , pp. 5482
    • Tacke, R.1    Boned, A.2    Goridis, C.3
  • 54
    • 0027529270 scopus 로고
    • A mitotic role for a novel fission yeast protein kinase dsk1 with cell cycle stage dependent phosphorylation and localization
    • Takeuchi, M. and Yanagida, M. (1993) A mitotic role for a novel fission yeast protein kinase dsk1 with cell cycle stage dependent phosphorylation and localization. Mol. Biol. Cell, 4, 247-260.
    • (1993) Mol. Biol. Cell , vol.4 , pp. 247-260
    • Takeuchi, M.1    Yanagida, M.2
  • 55
    • 0027236688 scopus 로고
    • Two distinct mechanisms for negative regulation of the Wee1 protein kinase
    • Tang, Z., Coleman, T R. and Dunphy, W.G (1993) Two distinct mechanisms for negative regulation of the Wee1 protein kinase. EMBO J., 12, 3427-3436.
    • (1993) EMBO J. , vol.12 , pp. 3427-3436
    • Tang, Z.1    Coleman, T.R.2    Dunphy, W.G.3
  • 56
    • 0026702493 scopus 로고
    • Adenosine phosphorothioates (ATP alpha S and ATP tau S) differentially affect the two steps of mammalian pre-mRNA splicing
    • Tazi, J., Daugeron, M.C., Cathala, G., Brunel, C. and Jeanteur, P. (1992) Adenosine phosphorothioates (ATP alpha S and ATP tau S) differentially affect the two steps of mammalian pre-mRNA splicing. J. Biol. Chem., 267, 4322-4326.
    • (1992) J. Biol. Chem. , vol.267 , pp. 4322-4326
    • Tazi, J.1    Daugeron, M.C.2    Cathala, G.3    Brunel, C.4    Jeanteur, P.5
  • 57
    • 0027420488 scopus 로고
    • Mechanism of interferon action: Evidence for intermolecular autophosphorylation and autoactivation of the interferon-induced, RNA-dependent protein kinase PKR
    • Thomis, D.C. and Samuel, C.E. (1993) Mechanism of interferon action: evidence for intermolecular autophosphorylation and autoactivation of the interferon-induced, RNA-dependent protein kinase PKR. J. Virol., 67, 7695-7700.
    • (1993) J. Virol. , vol.67 , pp. 7695-7700
    • Thomis, D.C.1    Samuel, C.E.2
  • 58
    • 0022924515 scopus 로고
    • Distribution of the 70K U1 RNA-associated protein during interphase and mitosis. Correlation with other U RNP particles and proteins of the nuclear matrix
    • Verheijen, R., Kuijpers, H., Vooijs, R. van Venrooij, W and Ramaekers, F. (1986) Distribution of the 70K U1 RNA-associated protein during interphase and mitosis. Correlation with other U RNP particles and proteins of the nuclear matrix. J. Cell Sci., 86, 173-190
    • (1986) J. Cell Sci. , vol.86 , pp. 173-190
    • Verheijen, R.1    Kuijpers, H.2    Vooijs, R.3    Van Venrooij, W.4    Ramaekers, F.5
  • 59
    • 0028295681 scopus 로고
    • 2.2 Mb of contiguous nucleotide sequence from chromosome II of C.elegans
    • Wilson, R. et al (1994) 2.2 Mb of contiguous nucleotide sequence from chromosome II of C.elegans. Nature, 368, 32-38.
    • (1994) Nature , vol.368 , pp. 32-38
    • Wilson, R.1
  • 60
    • 0027305702 scopus 로고
    • Identification of an snRNP-associated kinase activity that phosphorylates arginine/serine rich domains typical of splicing factors
    • Woppmann, A., Will, C.L., Kornstadt, U., Zuo, P., Manley, J.L. and Lührmann, R. (1993) Identification of an snRNP-associated kinase activity that phosphorylates arginine/serine rich domains typical of splicing factors. Nucleic Acids Res., 21, 2815-2822.
    • (1993) Nucleic Acids Res. , vol.21 , pp. 2815-2822
    • Woppmann, A.1    Will, C.L.2    Kornstadt, U.3    Zuo, P.4    Manley, J.L.5    Lührmann, R.6
  • 61
    • 0027137934 scopus 로고
    • Specific interactions between proteins implicated in splice site selection and regulated alternative splicing
    • Wu, J.Y. and Maniatis, T (1993) Specific interactions between proteins implicated in splice site selection and regulated alternative splicing. Cell, 75, 1061-1070.
    • (1993) Cell , vol.75 , pp. 1061-1070
    • Wu, J.Y.1    Maniatis, T.2
  • 62
    • 0028303751 scopus 로고
    • The Doa locus encodes a member of a new protein kinase family and is essential for eye and embryonic development in Drosophila melanogaster
    • Yun, B., Farkas, R., Lee, K. and Rabinow, L. (1994) The Doa locus encodes a member of a new protein kinase family and is essential for eye and embryonic development in Drosophila melanogaster. Genes Dev , 8, 1160-1173.
    • (1994) Genes Dev , vol.8 , pp. 1160-1173
    • Yun, B.1    Farkas, R.2    Lee, K.3    Rabinow, L.4
  • 63
    • 0026716104 scopus 로고
    • SR proteins, a conserved family of pre-mRNA splicing factors
    • Zahler, A.M., Lane, W.S., Stolk, J A. and Roth, M.B. (1992) SR proteins, a conserved family of pre-mRNA splicing factors. Genes Dev., 6, 837-847.
    • (1992) Genes Dev. , vol.6 , pp. 837-847
    • Zahler, A.M.1    Lane, W.S.2    Stolk, J.A.3    Roth, M.B.4
  • 64
    • 0027160003 scopus 로고
    • Distinct functions of SR proteins in alternative pre-mRNA splicing
    • Zahler, A.M., Neugebauer, K.M., Lane, W.S. and Roth, M.B. (1993a) Distinct functions of SR proteins in alternative pre-mRNA splicing. Science, 260, 219-222.
    • (1993) Science , vol.260 , pp. 219-222
    • Zahler, A.M.1    Neugebauer, K.M.2    Lane, W.S.3    Roth, M.B.4
  • 65
  • 66
    • 0028157664 scopus 로고
    • Atomic structure of the MAP kinase ERK2 at 2.3 Å resolution
    • Zhang, F , Strand, A., Robbins, D., Cobbs, M.H: and Goldsmith, E.J. (1994a) Atomic structure of the MAP kinase ERK2 at 2.3 Å resolution. Nature, 367, 704-710.
    • (1994) Nature , vol.367 , pp. 704-710
    • Zhang, F.1    Strand, A.2    Robbins, D.3    Cobbs, M.H.4    Goldsmith, E.J.5
  • 67
    • 0028600629 scopus 로고
    • Localization of pre-mRNA splicing in mammalian nuclei
    • Zhang, G., Taneja, K.L., Singer, R.H. and Green, M.R. (1994b) Localization of pre-mRNA splicing in mammalian nuclei. Nature, 372, 809-812.
    • (1994) Nature , vol.372 , pp. 809-812
    • Zhang, G.1    Taneja, K.L.2    Singer, R.H.3    Green, M.R.4
  • 68
    • 0027494389 scopus 로고
    • Functional domains of the human splicing factor ASF/SF2
    • Zuo, P. and Manley, J.L. (1993) Functional domains of the human splicing factor ASF/SF2. EMBO J., 12, 4727-4737.
    • (1993) EMBO J. , vol.12 , pp. 4727-4737
    • Zuo, P.1    Manley, J.L.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.