Cyclin D1 splice variants: Differential effects on localization, RB phosphorylation, and cellular transformation

Journal of Biological Chemistry

Volumn 278, Issue 32, 2003, Pages 30339-30347

  Solomon, David A ^a   Wang, Ying ^a   Fox, Sejal R ^a   Lambeck, Tah C ^a   Giesting, Sarah ^a   Lan, Zhengdao ^a   Senderowicz, Adrian M ^b   Knudsen, Erik S ^a  

^a UNIVERSITY OF CINCINNATI   (United States)

^b NATIONAL INSTITUTE OF DENTAL AND CRANIOFACIAL RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GENES; ONCOLOGY; TUMORS;

PHOSPHORYLATION;

PROTEINS;

CYCLIN D1; CYCLIN D1A; CYCLIN D1B; NUCLEAR PROTEIN; RETINOBLASTOMA PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CANCER RISK; CARCINOGENESIS; CELL NUCLEUS; CONTROLLED STUDY; DNA POLYMORPHISM; EMBRYO; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; HYPOTHESIS; MOUSE; MULTIPLE CANCER; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTO ONCOGENE; TUMOR SUPPRESSOR GENE;

3T3 CELLS; ALLELES; ALTERNATIVE SPLICING; ANIMALS; BINDING SITES; CELL CYCLE; CELL NUCLEUS; CELL TRANSFORMATION, NEOPLASTIC; CYCLIN D1; CYCLIN-DEPENDENT KINASE 4; CYCLIN-DEPENDENT KINASES; CYTOPLASM; DNA; FLOW CYTOMETRY; GREEN FLUORESCENT PROTEINS; HUMANS; IMMUNOBLOTTING; LUMINESCENT PROTEINS; MICE; MICROSCOPY, FLUORESCENCE; MODELS, GENETIC; NEOPLASMS; PHOSPHORYLATION; PLASMIDS; POLYMORPHISM, GENETIC; PRECIPITIN TESTS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTO-ONCOGENE PROTEINS; RETINOBLASTOMA PROTEIN; THREONINE; TIME FACTORS; TRANSCRIPTION, GENETIC; TRANSFECTION; TUMOR CELLS, CULTURED;

ANIMALIA;

EID: 0041528506     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M303969200     Document Type: Article

References (64)

1. Arnold, A. (1995) J. Investig. Med. 43, 543-549
2. Sherr, C. J., and McCormick, F. (2002) Cancer Cell 2, 103-112
3. Sherr, C. J. (2000) Harvey Lect. 96, 73-92
4. Sherr, C. J. (1996) Science 274, 1672-1677
5. Peters, G. (1994) J. Cell Sci. (Suppl.) 18, 89-96
6. Palmero, I., and Peters, G. (1996) Cancer Surv. 27, 351-367
7. Diehl, J. A. (2002) Cancer Biol. Ther. 1, 226-231
8. Motokura, T., Bloom, T., Kim, H. G., Juppner, H., Ruderman, J. V., Kronenberg, H. M., and Arnold, A. (1991) Nature 350, 512-515
9. Gillett, C., Fantl, V., Smith, R., Fisher, C., Bartek, J., Dickson, C., Barnes, D., and Peters, G. (1994) Cancer Res. 54, 1812-1817
10. Wang, T. C., Cardiff, R. D., Zukerberg, L., Lees, E., Arnold, A., and Schmidt, E. V. (1994) Nature 369, 669-671
11. Robles, A. I., Rodriguez-Puebla, M. L., Glick, A. B., Trempus, C., Hansen, L., Sicinski, P., Tennant, R. W., Weinberg, R. A., Yuspa, S. H., and Conti, C. J. (1998) Genes Dev. 12, 2469-2474
12. Yu, Q., Geng, Y., and Sicinski, P. (2001) Nature 411, 1017-1021
13. Lukas, J., Bartkova, J., and Bartek, J. (1996) Mol. Cell. Biol. 16, 6917-6925
14. Brown, J. R., Nigh, E., Lee, R. J., Ye, H., Thompson, M. A., Saudou, F., Pestell, R. G., and Greenberg, M. E. (1998) Mol. Cell. Biol. 18, 5609-5619
15. Roussel, M. F., Theodoras, A. M., Pagano, M., and Sherr, C. J. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 6837-6841
16. Sherr, C. J.(1995) Proc. Assoc. Am. Physicians 107, 181-186
17. Diehl, J. A., Zindy, F., and Sherr, C. J. (1997) Genes Dev. 11, 957-972
18. Diehl, J. A., Cheng, M., Roussel, M. F., and Sherr, C. J. (1998) Genes Dev. 12, 3499-3511
19. Meyerson, M., and Harlow, E. (1994) Mol. Cell. Biol. 14, 2077-2086
20. Matsushime, H., Ewen, M. E., Strom, D. K., Kato, J. Y., Hanks, S. K., Roussel, M. F., and Sherr, C. J. (1992) Cell 71, 323-334
21. Cheng, M., Sexl, V., Sherr, C. J., and Roussel, M. F. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 1091-1096
22. LaBaer, J., Garrett, M. D., Stevenson, L. F., Slingerland, J. M., Sandhu, C., Chou, H. S., Fattaey, A., and Harlow, E. (1997) Genes Dev. 11, 847-862
23. Resnitzky, D., Gossen, M., Bujard, H., and Reed, S. I. (1994) Mol. Cell. Biol. 14, 1669-1679
24. Resnitzky, D., and Reed, S. I. (1995) Mol. Cell. Biol. 15, 3463-3469
25. Lukas, J., Pagano, M., Staskova, Z., Draetta, G., and Bartek, J. (1994) Oncogene 9, 707-718
26. Lukas, J., Bartkova, J., Rohde, M., Strauss, M., and Bartek, J. (1995) Mol. Cell. Biol. 15, 2600-2611
27. Kato, J., Matsushime, H., Hiebert, S. W., Ewen, M. E., and Sherr, C. J. (1993) Genes Dev. 7, 331-342
28. Matsushime, H., Quelle, D. E., Shurtleff, S. A., Shibuya, M., Sherr, C. J., and Kato, J. Y. (1994) Mol. Cell. Biol. 14, 2066-2076
29. Ewen, M. E., Sluss, H. K., Sherr, C. J., Matsushime, H., Kato, J., and Livingston, D. M. (1993) Cell 73, 487-497
30. Dowdy, S. F., Hinds, P. W., Louie, K., Reed, S. I., Arnold, A., and Weinberg, R. A. (1993) Cell 73, 499-511
31. Wang, J. Y., Knudsen, E. S., and Welch, P. J. (1994) Adv. Cancer Res. 64, 25-85
32. Harbour, J. W., and Dean, D. C. (2000) Curr. Opin. Cell Biol. 12, 685-689
33. Harbour, J. W., and Dean, D. C. (2000) Genes Dev. 14, 2393-2409
34. Stevaux, O., and Dyson, N. J. (2002) Curr. Opin. Cell Biol. 14, 684-691
35. Mittnacht, S. (1998) Curr. Opin. Genet. Dev. 8, 21-27
36. Koh, J., Enders, G. H., Dynlacht, B. D., and Harlow, E. (1995) Nature 375, 506-510
37. Lukas, J., Muller, H., Bartkova, J., Spitkovsky, D., Kjerulff, A. A., Jansen-Durr, P., Strauss, M., and Bartek, J. (1994) J. Cell Biol. 125, 625-638
38. Lukas, J., Parry, D., Aagaard, L., Mann, D. J., Bartkova, J., Strauss, M., Peters, G., and Bartek, J. (1995) Nature 375, 503-506
39. Bates, S., Parry, D., Bonetta, L., Vousden, K., Dickson, C., and Peters, G. (1994) Oncogene 9, 1633-1640
40. Betticher, D. C., Thatcher, N., Altermatt, H. J., Hoban, P., Ryder, W. D., and Heighway, J. (1995) Oncogene 11, 1005-1011
41. Kong, S., Amos, C. I., Luthra, R., Lynch, P. M., Levin, B., and Frazier, M. L. (2000) Cancer Res. 60, 249-252
42. Howe, D., and Lynas, C. (2001) Haematologica 86, 563-569
43. Wang, L., Habuchi, T., Takahashi, T., Mitsumori, K., Kamoto, T., Kakehi, Y., Kakinuma, H., Sato, K., Nakamura, A., Ogawa, O., and Kato, T. (2002) Carcinogenesis 23, 257-264
44. Hosokawa, Y., and Arnold, A. (1998) Genes Chromosomes Cancer 22, 66-71
45. Holley, S. L., Parkes, G., Matthias, C., Bockmuhl, U., Jahnke, V., Leder, K., Strange, R. C., Fryer, A. A., and Hoban, P. R. (2001) Am. J. Pathol. 159, 1917-1924
46. Xiong, Y., Connolly, T., Futcher, B., and Beach, D. (1991) Cell 65, 691-699
47. Alt, J. R., Cleveland, J. L., Hannink, M., and Diehl, J. A. (2000) Genes Dev. 14, 3102-3114
48. Langenfeld, J., Kiyokawa, H., Sekula, D., Boyle, J., and Dmitrovsky, E. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 12070-12074
49. Hinds, P. W., Mittnacht, S., Dulic, V., Arnold, A., Reed, S. I., and Weinberg, R. A. (1992) Cell 70, 993-1006
50. Kitagawa, M., Higashi, H., Jung, H. K., Suzuki-Takahashi, I., Ikeda, M., Tamai, K., Kato, J., Segawa, K., Yoshida, E., Nishimura, S., and Taya, Y. (1996) EMBO J. 15, 7060-7069
51. Knudsen, K. E., Fribourg, A. F., Strobeck, M. W., Blanchard, J. M., and Knudsen, E. S. (1999) J. Biol. Chem. 274, 27632-27641
52. Gordon, C. (2002) Curr. Top. Microbiol. Immunol. 268, 175-184
53. Palmer, A., Mason, G. G., Paramio, J. M., Knecht, E., and Rivett, A. J. (1994) Eur J. Cell Biol. 64, 163-175
54. Agami, R., and Bernards, R. (2000) Cell 102, 55-66
55. Gladden, A. B., and Diehl, J. A. (2003) J. Biol. Chem. 278, 9754-9760
56. Scovassi, A. I., Stivala, L. A., Rossi, L., Bianchi, L., and Prosperi, E. (1997) Exp. Cell Res. 237, 127-134
57. Adams, P. D. (2001) Biochim Biophys Acta. 1471, M123-M133
58. Leng, X., Noble, M., Adams, P. D., Qin, J., and Harper, J. W. (2002) Mol. Cell. Biol. 22, 2242-2254
59. Adams, P. D., Li, X., Sellers, W. R., Baker, K. B., Leng, X., Harper, J. W., Taya, Y., and Kaelin, W. G., Jr. (1999) Mol. Cell. Biol. 19, 1068-1080
60. Schulman, B. A., Lindstrom, D. L., and Harlow, E. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 10453-10458
61. Angus, S. P., Fribourg, A. F., Markey, M. P., Williams, S. L., Horn, H. F., DeGregori, J., Kowalik, T. F., Fukasawa, K., and Knudsen, E. S. (2002) Exp. Cell Res. 276, 201-213
62. Fribourg, A. F., Knudsen, K. E., Strobeck, M. W., Lindhorst, C. M., and Knudsen, E. S. (2000) Cell Growth Differ. 11, 361-372
63. Knudsen, E. S., and Wang, J. Y. (1996) J. Biol. Chem. 271, 8313-8320
64. Knudsen, E. S., and Angus, S. P. (2003) Methods Mol. Biol. 218, 3-15