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Volumn 19, Issue 5-6, 2008, Pages 383-394

IFNγ signaling-Does it mean JAK-STAT?

Author keywords

Interferon gamma; STAT1 independent

Indexed keywords

GAMMA INTERFERON; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; JANUS KINASE; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; STAT PROTEIN; CCAAT ENHANCER BINDING PROTEIN BETA; GAMMA INTERFERON RECEPTOR; INTERFERON RECEPTOR; INTERFERON REGULATORY FACTOR; MHC CLASS II TRANSACTIVATOR PROTEIN; NUCLEAR PROTEIN; ONCOPROTEIN; PROTEIN KINASE B; PROTEIN KINASE C; PROTO ONCOGENE PROTEIN SPI 1; PROTO-ONCOGENE PROTEIN SPI-1; STAT1 PROTEIN; STAT3 PROTEIN; STAT5 PROTEIN; TRANSACTIVATOR PROTEIN; TRANSCRIPTION FACTOR AP 1; UNCLASSIFIED DRUG;

EID: 56949089974     PISSN: 13596101     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cytogfr.2008.08.004     Document Type: Review
Times cited : (254)

References (98)
  • 2
    • 0842266786 scopus 로고    scopus 로고
    • Interferon-gamma: an overview of signals, mechanisms and functions
    • [Epub 2003 Oct 2002]
    • Schroder K., Hertzog P.J., Ravasi T., and Hume D.A. Interferon-gamma: an overview of signals, mechanisms and functions. J Leukoc Biol 75 (2004) 163-189 [Epub 2003 Oct 2002]
    • (2004) J Leukoc Biol , vol.75 , pp. 163-189
    • Schroder, K.1    Hertzog, P.J.2    Ravasi, T.3    Hume, D.A.4
  • 3
    • 0036831613 scopus 로고    scopus 로고
    • New aspects of natural-killer-cell surveillance and therapy of cancer
    • Smyth M.J., Hayakawa Y., Takeda K., and Yagita H. New aspects of natural-killer-cell surveillance and therapy of cancer. Nat Rev Cancer 2 (2002) 850-861
    • (2002) Nat Rev Cancer , vol.2 , pp. 850-861
    • Smyth, M.J.1    Hayakawa, Y.2    Takeda, K.3    Yagita, H.4
  • 5
    • 0030455878 scopus 로고    scopus 로고
    • Interferon-gamma-receptor deficiency in an infant with fatal bacille Calmette-Guerin infection
    • Jouanguy E., Altare F., Lamhamedi S., Revy P., Emile J.F., Newport M., et al. Interferon-gamma-receptor deficiency in an infant with fatal bacille Calmette-Guerin infection. N Engl J Med 335 (1996) 1956-1961
    • (1996) N Engl J Med , vol.335 , pp. 1956-1961
    • Jouanguy, E.1    Altare, F.2    Lamhamedi, S.3    Revy, P.4    Emile, J.F.5    Newport, M.6
  • 6
    • 0031468410 scopus 로고    scopus 로고
    • Partial interferon-gamma receptor 1 deficiency in a child with tuberculoid bacillus Calmette-Guerin infection and a sibling with clinical tuberculosis
    • Jouanguy E., Lamhamedi-Cherradi S., Altare F., Fondaneche M.C., Tuerlinckx D., Blanche S., et al. Partial interferon-gamma receptor 1 deficiency in a child with tuberculoid bacillus Calmette-Guerin infection and a sibling with clinical tuberculosis. J Clin Invest 100 (1997) 2658-2664
    • (1997) J Clin Invest , vol.100 , pp. 2658-2664
    • Jouanguy, E.1    Lamhamedi-Cherradi, S.2    Altare, F.3    Fondaneche, M.C.4    Tuerlinckx, D.5    Blanche, S.6
  • 7
    • 1542542689 scopus 로고    scopus 로고
    • Autoantibodies to interferon-gamma in a patient with selective susceptibility to mycobacterial infection and organ-specific autoimmunity
    • [Epub 2003 December 2004]
    • Doffinger R., Helbert M.R., Barcenas-Morales G., Barcenas-Morales G., Yang K., Dupuis S., et al. Autoantibodies to interferon-gamma in a patient with selective susceptibility to mycobacterial infection and organ-specific autoimmunity. Clin Infect Dis 38 (2004) e10-e14 [Epub 2003 December 2004]
    • (2004) Clin Infect Dis , vol.38
    • Doffinger, R.1    Helbert, M.R.2    Barcenas-Morales, G.3    Barcenas-Morales, G.4    Yang, K.5    Dupuis, S.6
  • 8
    • 0019922739 scopus 로고
    • Defective immune interferon production and natural killer activity associated with poor neutrophil mobility and delayed umbilical cord separation
    • Davies E.G., Isaacs D., and Levinsky R.J. Defective immune interferon production and natural killer activity associated with poor neutrophil mobility and delayed umbilical cord separation. Clin Exp Immunol 50 (1982) 454-460
    • (1982) Clin Exp Immunol , vol.50 , pp. 454-460
    • Davies, E.G.1    Isaacs, D.2    Levinsky, R.J.3
  • 9
    • 0030062769 scopus 로고    scopus 로고
    • Kinase-negative mutants of JAK1 can sustain interferon-gamma-inducible gene expression but not an antiviral state
    • Briscoe J., Rogers N.C., Witthuhn B.A., Watling D., Harpur A.G., Wilks A.F., et al. Kinase-negative mutants of JAK1 can sustain interferon-gamma-inducible gene expression but not an antiviral state. EMBO J 15 (1996) 799-809
    • (1996) EMBO J , vol.15 , pp. 799-809
    • Briscoe, J.1    Rogers, N.C.2    Witthuhn, B.A.3    Watling, D.4    Harpur, A.G.5    Wilks, A.F.6
  • 10
    • 0029117304 scopus 로고
    • Maximal activation of transcription by STAT1 and STAT3 requires both tyrosine and serine phosphorylation
    • Wen Z., Zhong Z., and Darnell Jr. J.E. Maximal activation of transcription by STAT1 and STAT3 requires both tyrosine and serine phosphorylation. Cell 82 (1995) 241-250
    • (1995) Cell , vol.82 , pp. 241-250
    • Wen, Z.1    Zhong, Z.2    Darnell Jr., J.E.3
  • 11
    • 0030936627 scopus 로고    scopus 로고
    • GAS elements: a few nucleotides with a major impact on cytokine-induced gene expression
    • Decker T., Kovarik P., and Meinke A. GAS elements: a few nucleotides with a major impact on cytokine-induced gene expression. J Interf Cytok Res 17 (1997) 121-134
    • (1997) J Interf Cytok Res , vol.17 , pp. 121-134
    • Decker, T.1    Kovarik, P.2    Meinke, A.3
  • 12
    • 41849116690 scopus 로고    scopus 로고
    • Roles of unphosphorylated STATs in signaling
    • Yang J., and Stark G.R. Roles of unphosphorylated STATs in signaling. Cell Res 18 (2008) 443-451
    • (2008) Cell Res , vol.18 , pp. 443-451
    • Yang, J.1    Stark, G.R.2
  • 13
    • 0030875862 scopus 로고    scopus 로고
    • STAT1 serine phosphorylation occurs independently of tyrosine phosphorylation and requires an activated JAK2 kinase
    • Zhu X., Wen Z., Xu L.Z., and Darnell Jr. J.E. STAT1 serine phosphorylation occurs independently of tyrosine phosphorylation and requires an activated JAK2 kinase. Mol Cell Biol 17 (1997) 6618-6623
    • (1997) Mol Cell Biol , vol.17 , pp. 6618-6623
    • Zhu, X.1    Wen, Z.2    Xu, L.Z.3    Darnell Jr., J.E.4
  • 14
    • 0034658024 scopus 로고    scopus 로고
    • Serine phosphorylation of STATs
    • Decker T., and Kovarik P. Serine phosphorylation of STATs. Oncogene 19 (2000) 2628-2637
    • (2000) Oncogene , vol.19 , pp. 2628-2637
    • Decker, T.1    Kovarik, P.2
  • 15
    • 0346792731 scopus 로고    scopus 로고
    • Phosphorylation of the STAT1 transactivation domain is required for full-fledged IFN-gamma-dependent innate immunity
    • Varinou L., Ramsauer K., Karaghiosoff M., Kolbe T., Pfeffer K., Muller M., et al. Phosphorylation of the STAT1 transactivation domain is required for full-fledged IFN-gamma-dependent innate immunity. Immunity 19 (2003) 793-802
    • (2003) Immunity , vol.19 , pp. 793-802
    • Varinou, L.1    Ramsauer, K.2    Karaghiosoff, M.3    Kolbe, T.4    Pfeffer, K.5    Muller, M.6
  • 16
    • 0030024563 scopus 로고    scopus 로고
    • Targeted disruption of the mouse STAT1 gene results in compromised innate immunity to viral disease
    • Durbin J.E., Hackenmiller R., Simon M.C., and Levy D.E. Targeted disruption of the mouse STAT1 gene results in compromised innate immunity to viral disease. Cell 84 (1996) 443-450
    • (1996) Cell , vol.84 , pp. 443-450
    • Durbin, J.E.1    Hackenmiller, R.2    Simon, M.C.3    Levy, D.E.4
  • 17
    • 13344282731 scopus 로고    scopus 로고
    • Targeted disruption of the STAT1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway
    • Meraz M.A., White J.M., Sheehan K.C., Bach E.A., Rodig S.J., Dighe A.S., et al. Targeted disruption of the STAT1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway. Cell 84 (1996) 431-442
    • (1996) Cell , vol.84 , pp. 431-442
    • Meraz, M.A.1    White, J.M.2    Sheehan, K.C.3    Bach, E.A.4    Rodig, S.J.5    Dighe, A.S.6
  • 18
    • 0035854542 scopus 로고    scopus 로고
    • Impairment of mycobacterial but not viral immunity by a germline human STAT1 mutation
    • Dupuis S., Dargemont C., Fieschi C., Thomassin N., Rosenzweig S., Harris J., et al. Impairment of mycobacterial but not viral immunity by a germline human STAT1 mutation. Science 293 (2001) 300-303
    • (2001) Science , vol.293 , pp. 300-303
    • Dupuis, S.1    Dargemont, C.2    Fieschi, C.3    Thomassin, N.4    Rosenzweig, S.5    Harris, J.6
  • 19
    • 9244256797 scopus 로고    scopus 로고
    • Inherited disorders of cytokines
    • Picard C., and Casanova J.L. Inherited disorders of cytokines. Curr Opin Pediatr 16 (2004) 648-658
    • (2004) Curr Opin Pediatr , vol.16 , pp. 648-658
    • Picard, C.1    Casanova, J.L.2
  • 21
    • 24744437333 scopus 로고    scopus 로고
    • Critical roles for both STAT1-dependent and STAT1-independent pathways in the control of primary dengue virus infection in mice
    • Shresta S., Sharar K.L., Prigozhin D.M., Snider H.M., Beatty P.R., and Harris E. Critical roles for both STAT1-dependent and STAT1-independent pathways in the control of primary dengue virus infection in mice. J Immunol 175 (2005) 3946-3954
    • (2005) J Immunol , vol.175 , pp. 3946-3954
    • Shresta, S.1    Sharar, K.L.2    Prigozhin, D.M.3    Snider, H.M.4    Beatty, P.R.5    Harris, E.6
  • 22
    • 0036230176 scopus 로고    scopus 로고
    • Promotion of alpha/beta interferon induction during in vivo viral infection through alpha/beta interferon receptor/STAT1 system-dependent and -independent pathways
    • Malmgaard L., Salazar-Mather T.P., Lewis C.A., and Biron C.A. Promotion of alpha/beta interferon induction during in vivo viral infection through alpha/beta interferon receptor/STAT1 system-dependent and -independent pathways. J Virol 76 (2002) 4520-4525
    • (2002) J Virol , vol.76 , pp. 4520-4525
    • Malmgaard, L.1    Salazar-Mather, T.P.2    Lewis, C.A.3    Biron, C.A.4
  • 23
    • 0036476551 scopus 로고    scopus 로고
    • STAT1-dependent and -independent pathways in IFN-gamma-dependent signaling
    • Ramana C.V., Gil M.P., Schreiber R.D., and Stark G.R. STAT1-dependent and -independent pathways in IFN-gamma-dependent signaling. Trends Immunol 23 (2002) 96-101
    • (2002) Trends Immunol , vol.23 , pp. 96-101
    • Ramana, C.V.1    Gil, M.P.2    Schreiber, R.D.3    Stark, G.R.4
  • 24
    • 4744364574 scopus 로고    scopus 로고
    • Alternative activation of STAT1 and STAT3 in response to interferon-gamma
    • [Epub 42004 July 41627]
    • Qing Y., and Stark G.R. Alternative activation of STAT1 and STAT3 in response to interferon-gamma. J Biol Chem 279 (2004) 41679-41685 [Epub 42004 July 41627]
    • (2004) J Biol Chem , vol.279 , pp. 41679-41685
    • Qing, Y.1    Stark, G.R.2
  • 25
    • 0029909494 scopus 로고    scopus 로고
    • Activation of different STAT5 isoforms contributes to cell-type-restricted signaling in response to interferons
    • Meinke A., Barahmand-Pour F., Wohrl S., Stoiber D., and Decker T. Activation of different STAT5 isoforms contributes to cell-type-restricted signaling in response to interferons. Mol Cell Biol 16 (1996) 6937-6944
    • (1996) Mol Cell Biol , vol.16 , pp. 6937-6944
    • Meinke, A.1    Barahmand-Pour, F.2    Wohrl, S.3    Stoiber, D.4    Decker, T.5
  • 26
    • 11844305684 scopus 로고    scopus 로고
    • STAT1-independent induction of SOCS-3 by interferon-gamma is mediated by sustained activation of STAT3 in mouse embryonic fibroblasts
    • Ramana C.V., Kumar A., and Enelow R. STAT1-independent induction of SOCS-3 by interferon-gamma is mediated by sustained activation of STAT3 in mouse embryonic fibroblasts. Biochem Biophys Res Commun 327 (2005) 727-733
    • (2005) Biochem Biophys Res Commun , vol.327 , pp. 727-733
    • Ramana, C.V.1    Kumar, A.2    Enelow, R.3
  • 27
    • 33847740720 scopus 로고    scopus 로고
    • A novel c-Jun-dependent signal transduction pathway necessary for the transcriptional activation of interferon gamma response genes
    • Gough D.J., Sabapathy K., Ko E.Y., Arthur H.A., Schreiber R.D., Trapani J.A., et al. A novel c-Jun-dependent signal transduction pathway necessary for the transcriptional activation of interferon gamma response genes. J Biol Chem 282 (2007) 938-946
    • (2007) J Biol Chem , vol.282 , pp. 938-946
    • Gough, D.J.1    Sabapathy, K.2    Ko, E.Y.3    Arthur, H.A.4    Schreiber, R.D.5    Trapani, J.A.6
  • 29
    • 19344375679 scopus 로고    scopus 로고
    • A cytomegaloviral protein reveals a dual role for STAT2 in IFN-{gamma} signaling and antiviral responses
    • Zimmermann A., Trilling M., Wagner M., Wilborn M., Bubic I., Jonjic S., et al. A cytomegaloviral protein reveals a dual role for STAT2 in IFN-{gamma} signaling and antiviral responses. J Exp Med 201 (2005) 1543-1553
    • (2005) J Exp Med , vol.201 , pp. 1543-1553
    • Zimmermann, A.1    Trilling, M.2    Wagner, M.3    Wilborn, M.4    Bubic, I.5    Jonjic, S.6
  • 30
    • 0035823494 scopus 로고    scopus 로고
    • Roles of phosphatidylinositol 3-kinase in interferon-gamma-dependent phosphorylation of STAT1 on serine 727 and activation of gene expression
    • Nguyen H., Ramana C.V., Bayes J., and Stark G.R. Roles of phosphatidylinositol 3-kinase in interferon-gamma-dependent phosphorylation of STAT1 on serine 727 and activation of gene expression. J Biol Chem 276 (2001) 33361-33368
    • (2001) J Biol Chem , vol.276 , pp. 33361-33368
    • Nguyen, H.1    Ramana, C.V.2    Bayes, J.3    Stark, G.R.4
  • 31
    • 3042648414 scopus 로고    scopus 로고
    • A linear signal transduction pathway involving phosphatidylinositol 3-kinase, protein kinase Cepsilon, and MAPK in mesangial cells regulates interferon-gamma-induced STAT1alpha transcriptional activation
    • [Epub 22004 April 27313]
    • Choudhury G.G. A linear signal transduction pathway involving phosphatidylinositol 3-kinase, protein kinase Cepsilon, and MAPK in mesangial cells regulates interferon-gamma-induced STAT1alpha transcriptional activation. J Biol Chem 279 (2004) 27399-27409 [Epub 22004 April 27313]
    • (2004) J Biol Chem , vol.279 , pp. 27399-27409
    • Choudhury, G.G.1
  • 32
    • 0035873486 scopus 로고    scopus 로고
    • RNA-dependent protein kinase PKR is required for activation of NF-kappa B by IFN-gamma in a STAT1-independent pathway
    • Deb A., Haque S.J., Mogensen T., Silverman R.H., and Williams B.R. RNA-dependent protein kinase PKR is required for activation of NF-kappa B by IFN-gamma in a STAT1-independent pathway. J Immunol 166 (2001) 6170-6180
    • (2001) J Immunol , vol.166 , pp. 6170-6180
    • Deb, A.1    Haque, S.J.2    Mogensen, T.3    Silverman, R.H.4    Williams, B.R.5
  • 34
    • 0029133702 scopus 로고
    • Requirement for MAP kinase (ERK2) activity in interferon alpha- and interferon beta-stimulated gene expression through STAT proteins
    • David M., Petricoin III E., Benjamin C., Pine R., Weber M.J., and Larner A.C. Requirement for MAP kinase (ERK2) activity in interferon alpha- and interferon beta-stimulated gene expression through STAT proteins. Science 269 (1995) 1721-1723
    • (1995) Science , vol.269 , pp. 1721-1723
    • David, M.1    Petricoin III, E.2    Benjamin, C.3    Pine, R.4    Weber, M.J.5    Larner, A.C.6
  • 35
    • 33947402726 scopus 로고    scopus 로고
    • Interferon gamma-dependent transactivation of epidermal growth factor receptor
    • Burova E., Vassilenko K., Dorosh V., Gonchar I., and Nikolsky N. Interferon gamma-dependent transactivation of epidermal growth factor receptor. FEBS Lett 581 (2007) 1475-1480
    • (2007) FEBS Lett , vol.581 , pp. 1475-1480
    • Burova, E.1    Vassilenko, K.2    Dorosh, V.3    Gonchar, I.4    Nikolsky, N.5
  • 36
    • 0034733672 scopus 로고    scopus 로고
    • Cross talk between interferon-gamma and -alpha/beta signaling components in caveolar membrane domains
    • Takaoka A., Mitani Y., Suemori H., Sato M., Yocochi T., Noguchi S., et al. Cross talk between interferon-gamma and -alpha/beta signaling components in caveolar membrane domains. Science 288 (2000) 2357-2360
    • (2000) Science , vol.288 , pp. 2357-2360
    • Takaoka, A.1    Mitani, Y.2    Suemori, H.3    Sato, M.4    Yocochi, T.5    Noguchi, S.6
  • 37
    • 0029046971 scopus 로고
    • Combinatorial association and abundance of components of interferon-stimulated gene factor 3 dictate the selectivity of interferon responses
    • Bluyssen H.A., Muzaffar R., Vlieststra R.J., van der Made A.C., Leung S., Stark G.R., et al. Combinatorial association and abundance of components of interferon-stimulated gene factor 3 dictate the selectivity of interferon responses. Proc Natl Acad Sci USA 92 (1995) 5645-5649
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 5645-5649
    • Bluyssen, H.A.1    Muzaffar, R.2    Vlieststra, R.J.3    van der Made, A.C.4    Leung, S.5    Stark, G.R.6
  • 38
    • 0032102991 scopus 로고    scopus 로고
    • IFN-gamma priming up-regulates IFN-stimulated gene factor 3 (ISGF3) components, augmenting responsiveness of IFN-resistant melanoma cells to type I IFNs
    • Wong L.H., Hatzinisiriou I., Devenish R.J., and Ralph S.J. IFN-gamma priming up-regulates IFN-stimulated gene factor 3 (ISGF3) components, augmenting responsiveness of IFN-resistant melanoma cells to type I IFNs. J Immunol 160 (1998) 5475-5484
    • (1998) J Immunol , vol.160 , pp. 5475-5484
    • Wong, L.H.1    Hatzinisiriou, I.2    Devenish, R.J.3    Ralph, S.J.4
  • 39
    • 0036510590 scopus 로고    scopus 로고
    • Interferon-gamma-induced epithelial ICAM-1 expression and monocyte adhesion Involvement of protein kinase C-dependent c-Src tyrosine kinase activation pathway
    • [Epub 2001 December 7120]
    • Chang Y.J., Holtzman M.J., and Chen C.C. Interferon-gamma-induced epithelial ICAM-1 expression and monocyte adhesion Involvement of protein kinase C-dependent c-Src tyrosine kinase activation pathway. J Biol Chem 277 (2002) 7118-7126 [Epub 2001 December 7120]
    • (2002) J Biol Chem , vol.277 , pp. 7118-7126
    • Chang, Y.J.1    Holtzman, M.J.2    Chen, C.C.3
  • 41
    • 0037064119 scopus 로고    scopus 로고
    • Requirement of phosphoinositide 3-kinase and Akt for interferon-beta-mediated induction of the beta-R1 (SCYB11) gene
    • [Epub 32002 August 38456]
    • Rani M.R., Hibbert L., Sizemore N., Stark G.R., and Ransohoff R.M. Requirement of phosphoinositide 3-kinase and Akt for interferon-beta-mediated induction of the beta-R1 (SCYB11) gene. J Biol Chem 277 (2002) 38456-38461 [Epub 32002 August 38456]
    • (2002) J Biol Chem , vol.277 , pp. 38456-38461
    • Rani, M.R.1    Hibbert, L.2    Sizemore, N.3    Stark, G.R.4    Ransohoff, R.M.5
  • 42
    • 0034595093 scopus 로고    scopus 로고
    • Interferon-dependent activation of the serine kinase PI 3′-kinase requires engagement of the IRS pathway but not the Stat pathway
    • Uddin S., Majchrzak B., Wang P.C., Modi S., Khan M.K., Fish E.N., et al. Interferon-dependent activation of the serine kinase PI 3′-kinase requires engagement of the IRS pathway but not the Stat pathway. Biochem Biophys Res Commun 270 (2000) 158-162
    • (2000) Biochem Biophys Res Commun , vol.270 , pp. 158-162
    • Uddin, S.1    Majchrzak, B.2    Wang, P.C.3    Modi, S.4    Khan, M.K.5    Fish, E.N.6
  • 43
    • 33645101274 scopus 로고    scopus 로고
    • MyD88-mediated stabilization of interferon-gamma-induced cytokine and chemokine mRNA
    • Sun D., and Ding A. MyD88-mediated stabilization of interferon-gamma-induced cytokine and chemokine mRNA. Nat Immunol 7 (2006) 375-381
    • (2006) Nat Immunol , vol.7 , pp. 375-381
    • Sun, D.1    Ding, A.2
  • 46
    • 0035808316 scopus 로고    scopus 로고
    • ERK1 and ERK2 activate CCAAAT/enhancer-binding protein-beta-dependent gene transcription in response to interferon-gamma
    • Hu J., Roy S.K., Shapiro P.S., Rodig S.R., Reddy S.P., Platanias L.C., et al. ERK1 and ERK2 activate CCAAAT/enhancer-binding protein-beta-dependent gene transcription in response to interferon-gamma. J Biol Chem 276 (2001) 287-297
    • (2001) J Biol Chem , vol.276 , pp. 287-297
    • Hu, J.1    Roy, S.K.2    Shapiro, P.S.3    Rodig, S.R.4    Reddy, S.P.5    Platanias, L.C.6
  • 48
    • 0037062498 scopus 로고    scopus 로고
    • MEKK1 plays a critical role in activating the transcription factor C/EBP-beta-dependent gene expression in response to IFN-gamma
    • Roy S.K., Hu J., Meng Q., Xia Y., Shapiro P.S., Reddy S.P., et al. MEKK1 plays a critical role in activating the transcription factor C/EBP-beta-dependent gene expression in response to IFN-gamma. Proc Natl Acad Sci USA 99 (2002) 7945-7950
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 7945-7950
    • Roy, S.K.1    Hu, J.2    Meng, Q.3    Xia, Y.4    Shapiro, P.S.5    Reddy, S.P.6
  • 49
    • 19544390842 scopus 로고    scopus 로고
    • Interferon-gamma-dependent tyrosine phosphorylation of MEKK4 via Pyk2 is regulated by annexin II and SHP2 in keratinocytes
    • Halfter U.M., Derbyshire Z.E., and Vaillancourt R.R. Interferon-gamma-dependent tyrosine phosphorylation of MEKK4 via Pyk2 is regulated by annexin II and SHP2 in keratinocytes. Biochem J 388 (2005) 17-28
    • (2005) Biochem J , vol.388 , pp. 17-28
    • Halfter, U.M.1    Derbyshire, Z.E.2    Vaillancourt, R.R.3
  • 50
    • 0036789933 scopus 로고    scopus 로고
    • Ramsauer K, Sadzak I, Porras A, Pilz A, Nebreda AR, Decker T, et al. p38 MAPK enhances STAT1-dependent transcription independently of Ser-727 phosphorylation. Proc Natl Acad Sci USA 2002;99:12859-64 [Epub 12002 September 12813].
    • Ramsauer K, Sadzak I, Porras A, Pilz A, Nebreda AR, Decker T, et al. p38 MAPK enhances STAT1-dependent transcription independently of Ser-727 phosphorylation. Proc Natl Acad Sci USA 2002;99:12859-64 [Epub 12002 September 12813].
  • 51
    • 18844457095 scopus 로고    scopus 로고
    • Mechanisms of Type-I- and Type-II-interferon-mediated signalling
    • Platanias L.C. Mechanisms of Type-I- and Type-II-interferon-mediated signalling. Nat Rev Immunol 5 (2005) 375
    • (2005) Nat Rev Immunol , vol.5 , pp. 375
    • Platanias, L.C.1
  • 53
    • 0141958148 scopus 로고    scopus 로고
    • IFN-gamma-induced MHC class II expression: transactivation of class II transactivator promoter IV by IFN regulatory factor-1 is regulated by protein kinase C-alpha
    • Giroux M., Schmidt M., and Descoteaux A. IFN-gamma-induced MHC class II expression: transactivation of class II transactivator promoter IV by IFN regulatory factor-1 is regulated by protein kinase C-alpha. J Immunol 171 (2003) 4187-4194
    • (2003) J Immunol , vol.171 , pp. 4187-4194
    • Giroux, M.1    Schmidt, M.2    Descoteaux, A.3
  • 55
    • 1342329649 scopus 로고    scopus 로고
    • Differential role of Janus family kinases (JAKs) in interferon-gamma-induced lung epithelial ICAM-1 expression: involving protein interactions between JAKs, phospholipase Cgamma, c-Src, and STAT1
    • Chang Y.J., Holtzman M.J., and Chen C.C. Differential role of Janus family kinases (JAKs) in interferon-gamma-induced lung epithelial ICAM-1 expression: involving protein interactions between JAKs, phospholipase Cgamma, c-Src, and STAT1. Mol Pharmacol 65 (2004) 589-598
    • (2004) Mol Pharmacol , vol.65 , pp. 589-598
    • Chang, Y.J.1    Holtzman, M.J.2    Chen, C.C.3
  • 56
    • 0032845125 scopus 로고    scopus 로고
    • Interacting regions in STAT3 and c-Jun that participate in cooperative transcriptional activation
    • Zhang X., Wrzeszczynska M.H., Horvath C.M., and Darnell Jr. J.E. Interacting regions in STAT3 and c-Jun that participate in cooperative transcriptional activation. Mol Cell Biol 19 (1999) 7138-7146
    • (1999) Mol Cell Biol , vol.19 , pp. 7138-7146
    • Zhang, X.1    Wrzeszczynska, M.H.2    Horvath, C.M.3    Darnell Jr., J.E.4
  • 57
    • 0036467492 scopus 로고    scopus 로고
    • The interferon-alpha/beta system in antiviral responses: a multimodal machinery of gene regulation by the IRF family of transcription factors
    • Taniguchi T., and Takaoka A. The interferon-alpha/beta system in antiviral responses: a multimodal machinery of gene regulation by the IRF family of transcription factors. Curr Opin Immunol 14 (2002) 111-116
    • (2002) Curr Opin Immunol , vol.14 , pp. 111-116
    • Taniguchi, T.1    Takaoka, A.2
  • 58
    • 0028007114 scopus 로고
    • Accelerated exon skipping of IRF-1 mRNA in human myelodysplasia/leukemia; a possible mechanism of tumor suppressor inactivation
    • Harada H., Kondo T., Ogawa S., Tamura T., Kitagawa M., Tanaka N., et al. Accelerated exon skipping of IRF-1 mRNA in human myelodysplasia/leukemia; a possible mechanism of tumor suppressor inactivation. Oncogene 9 (1994) 3313-3320
    • (1994) Oncogene , vol.9 , pp. 3313-3320
    • Harada, H.1    Kondo, T.2    Ogawa, S.3    Tamura, T.4    Kitagawa, M.5    Tanaka, N.6
  • 59
    • 0028097932 scopus 로고
    • Tyrosine phosphorylated p91 binds to a single element in the ISGF2/IRF-1 promoter to mediate induction by IFN alpha and IFN gamma, and is likely to autoregulate the p91 gene
    • Pine R., Canova A., and Schindler C. Tyrosine phosphorylated p91 binds to a single element in the ISGF2/IRF-1 promoter to mediate induction by IFN alpha and IFN gamma, and is likely to autoregulate the p91 gene. EMBO J 13 (1994) 158-167
    • (1994) EMBO J , vol.13 , pp. 158-167
    • Pine, R.1    Canova, A.2    Schindler, C.3
  • 60
    • 33847271713 scopus 로고    scopus 로고
    • Distinct modes of action applied by transcription factors STAT1 and IRF1 to initiate transcription of the IFN-gamma-inducible gbp2 gene
    • Ramsauer K., Farlik M., Zupkovitz G., Seiser C., Kroger A., Hauser H., et al. Distinct modes of action applied by transcription factors STAT1 and IRF1 to initiate transcription of the IFN-gamma-inducible gbp2 gene. Proc Natl Acad Sci USA 104 (2007) 2849-2854
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 2849-2854
    • Ramsauer, K.1    Farlik, M.2    Zupkovitz, G.3    Seiser, C.4    Kroger, A.5    Hauser, H.6
  • 61
    • 0037088572 scopus 로고    scopus 로고
    • Cooperation of STAT-1 and IRF-1 in interferon-gamma-induced transcription of the gp91(phox) gene
    • Kumatori A., Yang D., Suzuki S., and Nakamura M. Cooperation of STAT-1 and IRF-1 in interferon-gamma-induced transcription of the gp91(phox) gene. J Biol Chem 277 (2002) 9103-9111
    • (2002) J Biol Chem , vol.277 , pp. 9103-9111
    • Kumatori, A.1    Yang, D.2    Suzuki, S.3    Nakamura, M.4
  • 62
    • 0034254726 scopus 로고    scopus 로고
    • How STAT1 mediates constitutive gene expression: a complex of unphosphorylated STAT1 and IRF1 supports transcription of the LMP2 gene
    • Chatterjee-Kishore M., Wright K.L., Ting J.P., and Stark G.R. How STAT1 mediates constitutive gene expression: a complex of unphosphorylated STAT1 and IRF1 supports transcription of the LMP2 gene. EMBO J 19 (2000) 4111-4122
    • (2000) EMBO J , vol.19 , pp. 4111-4122
    • Chatterjee-Kishore, M.1    Wright, K.L.2    Ting, J.P.3    Stark, G.R.4
  • 63
    • 0025292308 scopus 로고
    • An interferon gamma-regulated protein that binds the interferon-inducible enhancer element of major histocompatibility complex class I genes
    • Driggers P.H., Ennist D.L., Gleason S.L., Mak W.H., Marks M.S., Levi B.Z., et al. An interferon gamma-regulated protein that binds the interferon-inducible enhancer element of major histocompatibility complex class I genes. Proc Natl Acad Sci USA 87 (1990) 3743-3747
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 3743-3747
    • Driggers, P.H.1    Ennist, D.L.2    Gleason, S.L.3    Mak, W.H.4    Marks, M.S.5    Levi, B.Z.6
  • 64
    • 9244249776 scopus 로고    scopus 로고
    • Expression of IFN regulatory factor family proteins in lymphocytes. Induction of STAT-1 and IFN consensus sequence binding protein expression by T cell activation
    • Nelson N., Kanno Y., Hong C., Contursi C., Fujita T., Fowlkes B.J., et al. Expression of IFN regulatory factor family proteins in lymphocytes. Induction of STAT-1 and IFN consensus sequence binding protein expression by T cell activation. J Immunol 156 (1996) 3711-3720
    • (1996) J Immunol , vol.156 , pp. 3711-3720
    • Nelson, N.1    Kanno, Y.2    Hong, C.3    Contursi, C.4    Fujita, T.5    Fowlkes, B.J.6
  • 65
    • 0030899516 scopus 로고    scopus 로고
    • Phosphorylation events modulate the ability of interferon consensus sequence binding protein to interact with interferon regulatory factors and to bind DNA
    • Sharf R., Meraro D., Azriel A., Thornton A.M., Ozato K., Petricoin E.F., et al. Phosphorylation events modulate the ability of interferon consensus sequence binding protein to interact with interferon regulatory factors and to bind DNA. J Biol Chem 272 (1997) 9785-9792
    • (1997) J Biol Chem , vol.272 , pp. 9785-9792
    • Sharf, R.1    Meraro, D.2    Azriel, A.3    Thornton, A.M.4    Ozato, K.5    Petricoin, E.F.6
  • 66
    • 33747063564 scopus 로고    scopus 로고
    • Inhibition of monocytic differentiation by phosphorylation-deficient STAT1 is associated with impaired expression of STAT2 ICSBP/IRF8 and C/EBPepsilon
    • Dimberg A., Karehed K., Nilsson K., and Oberg F. Inhibition of monocytic differentiation by phosphorylation-deficient STAT1 is associated with impaired expression of STAT2 ICSBP/IRF8 and C/EBPepsilon. Scand J Immunol 64 (2006) 271-279
    • (2006) Scand J Immunol , vol.64 , pp. 271-279
    • Dimberg, A.1    Karehed, K.2    Nilsson, K.3    Oberg, F.4
  • 67
    • 0029968925 scopus 로고    scopus 로고
    • Mice lacking the MHC class II transactivator (CIITA) show tissue-specific impairment of MHC class II expression
    • Chang C.H., Guerder S., Hong S.C., van Ewijk W., and Flavell R.A. Mice lacking the MHC class II transactivator (CIITA) show tissue-specific impairment of MHC class II expression. Immunity 4 (1996) 167-178
    • (1996) Immunity , vol.4 , pp. 167-178
    • Chang, C.H.1    Guerder, S.2    Hong, S.C.3    van Ewijk, W.4    Flavell, R.A.5
  • 68
    • 0036839436 scopus 로고    scopus 로고
    • Modulation of gene expression by the MHC class II transactivator
    • Nagarajan U.M., Bushey A., and Boss J.M. Modulation of gene expression by the MHC class II transactivator. J Immunol 169 (2002) 5078-5088
    • (2002) J Immunol , vol.169 , pp. 5078-5088
    • Nagarajan, U.M.1    Bushey, A.2    Boss, J.M.3
  • 69
    • 0032006255 scopus 로고    scopus 로고
    • Activation of the MHC class II transactivator CIITA by interferon-gamma requires cooperative interaction between STAT1 and USF-1
    • Muhlethaler-Mottet A., Di Berardino W., Otten L.A., and Mach B. Activation of the MHC class II transactivator CIITA by interferon-gamma requires cooperative interaction between STAT1 and USF-1. Immunity 8 (1998) 157-166
    • (1998) Immunity , vol.8 , pp. 157-166
    • Muhlethaler-Mottet, A.1    Di Berardino, W.2    Otten, L.A.3    Mach, B.4
  • 70
    • 0033789216 scopus 로고    scopus 로고
    • Lack of CIITA expression is central to the absence of antigen presentation functions of trophoblast cells and is caused by methylation of the IFN-gamma inducible promoter (PIV) of CIITA
    • van den Elsen P.J., van der Stoep N., Vietor H.E., Wilson L., van Zutphen M., and Gobin S.J. Lack of CIITA expression is central to the absence of antigen presentation functions of trophoblast cells and is caused by methylation of the IFN-gamma inducible promoter (PIV) of CIITA. Hum Immunol 61 (2000) 850-862
    • (2000) Hum Immunol , vol.61 , pp. 850-862
    • van den Elsen, P.J.1    van der Stoep, N.2    Vietor, H.E.3    Wilson, L.4    van Zutphen, M.5    Gobin, S.J.6
  • 71
    • 0034725041 scopus 로고    scopus 로고
    • CCAAT/enhancer-binding protein-beta regulates interferon-induced transcription through a novel element
    • Roy S.K., Wachira S.J., Weihua X., Hu J., and Kalvakolanu D.V. CCAAT/enhancer-binding protein-beta regulates interferon-induced transcription through a novel element. J Biol Chem 275 (2000) 12626-12632
    • (2000) J Biol Chem , vol.275 , pp. 12626-12632
    • Roy, S.K.1    Wachira, S.J.2    Weihua, X.3    Hu, J.4    Kalvakolanu, D.V.5
  • 72
    • 42149123787 scopus 로고    scopus 로고
    • Critical role for transcription factor C/EBP-beta in regulating the expression of death-associated protein kinase 1
    • Gade P., Roy S.K., Li H., Nallar S.C., and Kalvakolanu D.V. Critical role for transcription factor C/EBP-beta in regulating the expression of death-associated protein kinase 1. Mol Cell Biol 28 (2008) 2528-2548
    • (2008) Mol Cell Biol , vol.28 , pp. 2528-2548
    • Gade, P.1    Roy, S.K.2    Li, H.3    Nallar, S.C.4    Kalvakolanu, D.V.5
  • 73
    • 0028361784 scopus 로고
    • Restriction of interferon gamma responsiveness and basal expression of the myeloid human Fc gamma R1b gene is mediated by a functional PU 1 site and a transcription initiator consensus
    • Eichbaum Q.G., Iyer R., Raveh D.P., Mathieu C., and Ezekowitz R.A. Restriction of interferon gamma responsiveness and basal expression of the myeloid human Fc gamma R1b gene is mediated by a functional PU 1 site and a transcription initiator consensus. J Exp Med 179 (1994) 1985-1996
    • (1994) J Exp Med , vol.179 , pp. 1985-1996
    • Eichbaum, Q.G.1    Iyer, R.2    Raveh, D.P.3    Mathieu, C.4    Ezekowitz, R.A.5
  • 74
    • 1842477089 scopus 로고    scopus 로고
    • IFN-gamma induces gp91phox expression in human monocytes via protein kinase C-dependent phosphorylation of PU 1
    • Mazzi P., Donini M., Margotto D., Wientjes F., and Dusi S. IFN-gamma induces gp91phox expression in human monocytes via protein kinase C-dependent phosphorylation of PU 1. J Immunol 172 (2004) 4941-4947
    • (2004) J Immunol , vol.172 , pp. 4941-4947
    • Mazzi, P.1    Donini, M.2    Margotto, D.3    Wientjes, F.4    Dusi, S.5
  • 75
    • 34249665503 scopus 로고    scopus 로고
    • PU 1 and ICSBP control constitutive and IFN-gamma-regulated Tlr9 gene expression in mouse macrophages
    • Schroder K., Lichtinger M., Irvine K.M., Brion K., Trieu A., Ross I.L., et al. PU 1 and ICSBP control constitutive and IFN-gamma-regulated Tlr9 gene expression in mouse macrophages. J Leukoc Biol 81 (2007) 1577-1590
    • (2007) J Leukoc Biol , vol.81 , pp. 1577-1590
    • Schroder, K.1    Lichtinger, M.2    Irvine, K.M.3    Brion, K.4    Trieu, A.5    Ross, I.L.6
  • 76
    • 0035851121 scopus 로고    scopus 로고
    • SHP1 protein-tyrosine phosphatase inhibits gp91PHOX and p67PHOX expression by inhibiting interaction of PU.1, IRF1, interferon consensus sequence-binding protein, and CREB-binding protein with homologous Cis elements in the CYBB and NCF2 genes
    • Kautz B., Kakar R., David E., and Eklund E.A. SHP1 protein-tyrosine phosphatase inhibits gp91PHOX and p67PHOX expression by inhibiting interaction of PU.1, IRF1, interferon consensus sequence-binding protein, and CREB-binding protein with homologous Cis elements in the CYBB and NCF2 genes. J Biol Chem 276 (2001) 37868-37878
    • (2001) J Biol Chem , vol.276 , pp. 37868-37878
    • Kautz, B.1    Kakar, R.2    David, E.3    Eklund, E.A.4
  • 77
    • 0034677195 scopus 로고    scopus 로고
    • Regulation of c-myc expression by IFN-gamma through STAT1-dependent and -independent pathways
    • Ramana C.V., Grammatikakis N., Chernov M., Nguyen H., Goh K.C., Williams B.R., et al. Regulation of c-myc expression by IFN-gamma through STAT1-dependent and -independent pathways. EMBO J 19 (2000) 263-272
    • (2000) EMBO J , vol.19 , pp. 263-272
    • Ramana, C.V.1    Grammatikakis, N.2    Chernov, M.3    Nguyen, H.4    Goh, K.C.5    Williams, B.R.6
  • 78
    • 0029655458 scopus 로고    scopus 로고
    • The antiviral state induced by alpha interferon and gamma interferon requires transcriptionally active STAT1 protein
    • Horvath C.M., and Darnell Jr. J.E. The antiviral state induced by alpha interferon and gamma interferon requires transcriptionally active STAT1 protein. J Virol 70 (1996) 647-650
    • (1996) J Virol , vol.70 , pp. 647-650
    • Horvath, C.M.1    Darnell Jr., J.E.2
  • 79
    • 35648948989 scopus 로고    scopus 로고
    • Activation of a subset of genes by IFN-gamma requires IKKbeta but not interferon-dependent activation of NF-kappaB
    • Shultz D.B., Fuller J.D., Yang Y., Sizemore N., Rani M.R., and Stark G.R. Activation of a subset of genes by IFN-gamma requires IKKbeta but not interferon-dependent activation of NF-kappaB. J Interf Cytok Res 27 (2007) 875-884
    • (2007) J Interf Cytok Res , vol.27 , pp. 875-884
    • Shultz, D.B.1    Fuller, J.D.2    Yang, Y.3    Sizemore, N.4    Rani, M.R.5    Stark, G.R.6
  • 80
    • 2542523110 scopus 로고    scopus 로고
    • Inhibitor of kappaB kinase is required to activate a subset of interferon gamma-stimulated genes
    • [Epub 2004 May 7917]
    • Sizemore N., Agarwal A., Das K., Lerner N., Sulak M., Rani S., et al. Inhibitor of kappaB kinase is required to activate a subset of interferon gamma-stimulated genes. Proc Natl Acad Sci USA 101 (2004) 7994-7998 [Epub 2004 May 7917]
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 7994-7998
    • Sizemore, N.1    Agarwal, A.2    Das, K.3    Lerner, N.4    Sulak, M.5    Rani, S.6
  • 81
    • 0037405861 scopus 로고    scopus 로고
    • Critical role of the transcription factor AP-1 for the constitutive and interferon-induced expression of IFI 16
    • Clarke C.J., Apostolidis V., Hii L.L., Gough D.J., Trapani J.A., and Johnstone R.W. Critical role of the transcription factor AP-1 for the constitutive and interferon-induced expression of IFI 16. J Cell Biochem 89 (2003) 80-93
    • (2003) J Cell Biochem , vol.89 , pp. 80-93
    • Clarke, C.J.1    Apostolidis, V.2    Hii, L.L.3    Gough, D.J.4    Trapani, J.A.5    Johnstone, R.W.6
  • 82
    • 0033103955 scopus 로고    scopus 로고
    • Transcriptional inhibition of stromelysin by interferon-gamma in normal human fibroblasts is mediated by the AP-1 domain
    • Lewis M., Amento E.P., and Unemori E.N. Transcriptional inhibition of stromelysin by interferon-gamma in normal human fibroblasts is mediated by the AP-1 domain. J Cell Biochem 72 (1999) 373-386
    • (1999) J Cell Biochem , vol.72 , pp. 373-386
    • Lewis, M.1    Amento, E.P.2    Unemori, E.N.3
  • 83
  • 84
    • 0025685264 scopus 로고
    • Interferon gamma plays a critical role in induced cell death of effector T cell: a possible third mechanism of self-tolerance
    • Liu Y., and Janeway Jr. C.A. Interferon gamma plays a critical role in induced cell death of effector T cell: a possible third mechanism of self-tolerance. J Exp Med 172 (1990) 1735-1739
    • (1990) J Exp Med , vol.172 , pp. 1735-1739
    • Liu, Y.1    Janeway Jr., C.A.2
  • 85
    • 0029015464 scopus 로고
    • Lack of interferon gamma receptor beta chain and the prevention of interferon gamma signaling in TH1 cells
    • Pernis A., Gupta S., Gollob K.J., Garfein E., Coffman R.L., Schindler C., et al. Lack of interferon gamma receptor beta chain and the prevention of interferon gamma signaling in TH1 cells. Science 269 (1995) 245-247
    • (1995) Science , vol.269 , pp. 245-247
    • Pernis, A.1    Gupta, S.2    Gollob, K.J.3    Garfein, E.4    Coffman, R.L.5    Schindler, C.6
  • 86
    • 0027240840 scopus 로고
    • The response of gamma interferon activation factor is under developmental control in cells of the macrophage lineage
    • Eilers A., Seegert D., Schindler C., Baccarini M., and Decker T. The response of gamma interferon activation factor is under developmental control in cells of the macrophage lineage. Mol Cell Biol 13 (1993) 3245-3254
    • (1993) Mol Cell Biol , vol.13 , pp. 3245-3254
    • Eilers, A.1    Seegert, D.2    Schindler, C.3    Baccarini, M.4    Decker, T.5
  • 87
    • 0030851840 scopus 로고    scopus 로고
    • Regulation of interferon-alpha responsiveness by the duration of Janus kinase activity
    • Lee C.K., Bluyssen H.A., and Levy D.E. Regulation of interferon-alpha responsiveness by the duration of Janus kinase activity. J Biol Chem 272 (1997) 21872-21877
    • (1997) J Biol Chem , vol.272 , pp. 21872-21877
    • Lee, C.K.1    Bluyssen, H.A.2    Levy, D.E.3
  • 88
    • 0025270456 scopus 로고
    • Synergistic interaction between interferon-alpha and interferon-gamma through induced synthesis of one subunit of the transcription factor ISGF3
    • Levy D.E., Lew D.J., Decker T., Kessler D.S., and Darnell Jr. J.E. Synergistic interaction between interferon-alpha and interferon-gamma through induced synthesis of one subunit of the transcription factor ISGF3. EMBO J 9 (1990) 1105-1111
    • (1990) EMBO J , vol.9 , pp. 1105-1111
    • Levy, D.E.1    Lew, D.J.2    Decker, T.3    Kessler, D.S.4    Darnell Jr., J.E.5
  • 89
    • 0030712998 scopus 로고    scopus 로고
    • Interferon-resistant human melanoma cells are deficient in ISGF3 components, STAT1, STAT2, and p48-ISGF3gamma
    • Wong L.H., Krauer K.G., Hatzinisiriou I., Estcourt M.J., Hersey P., Tam N.D., et al. Interferon-resistant human melanoma cells are deficient in ISGF3 components, STAT1, STAT2, and p48-ISGF3gamma. J Biol Chem 272 (1997) 28779-28785
    • (1997) J Biol Chem , vol.272 , pp. 28779-28785
    • Wong, L.H.1    Krauer, K.G.2    Hatzinisiriou, I.3    Estcourt, M.J.4    Hersey, P.5    Tam, N.D.6
  • 90
    • 0018098799 scopus 로고
    • Interferon affects both G1 and S + G2 in cells stimulated from quiescence to growth
    • Balkwill F., and Taylor-Papadimitriou J. Interferon affects both G1 and S + G2 in cells stimulated from quiescence to growth. Nature 274 (1978) 798-800
    • (1978) Nature , vol.274 , pp. 798-800
    • Balkwill, F.1    Taylor-Papadimitriou, J.2
  • 91
    • 0033166302 scopus 로고    scopus 로고
    • Interferon gamma induces the expression of p21waf-1 and arrests macrophage cell cycle, preventing induction of apoptosis
    • Xaus J., Cardo M., Valledor A.F., Soler C., Lloberas J., and Celada A. Interferon gamma induces the expression of p21waf-1 and arrests macrophage cell cycle, preventing induction of apoptosis. Immunity 11 (1999) 103-113
    • (1999) Immunity , vol.11 , pp. 103-113
    • Xaus, J.1    Cardo, M.2    Valledor, A.F.3    Soler, C.4    Lloberas, J.5    Celada, A.6
  • 93
    • 0032806841 scopus 로고    scopus 로고
    • CrkL and CrkII participate in the generation of the growth inhibitory effects of interferons on primary hematopoietic progenitors
    • Platanias L.C., Uddin S., Bruno E., Korkmaz M., Ahmad S., Alsayed Y., et al. CrkL and CrkII participate in the generation of the growth inhibitory effects of interferons on primary hematopoietic progenitors. Exp Hematol 27 (1999) 1315-1321
    • (1999) Exp Hematol , vol.27 , pp. 1315-1321
    • Platanias, L.C.1    Uddin, S.2    Bruno, E.3    Korkmaz, M.4    Ahmad, S.5    Alsayed, Y.6
  • 94
    • 0037645144 scopus 로고    scopus 로고
    • A PI-3 kinase-dependent STAT1-independent signaling pathway regulates interferon-stimulated monocyte adhesion
    • Navarro A., Anand-Apte B., Tanabe Y., Feldman G., and Larner A.C. A PI-3 kinase-dependent STAT1-independent signaling pathway regulates interferon-stimulated monocyte adhesion. J Leukoc Biol 73 (2003) 540-545
    • (2003) J Leukoc Biol , vol.73 , pp. 540-545
    • Navarro, A.1    Anand-Apte, B.2    Tanabe, Y.3    Feldman, G.4    Larner, A.C.5
  • 95
    • 0033537739 scopus 로고    scopus 로고
    • Severe liver degeneration in mice lacking the IkappaB kinase 2 gene
    • Li Q., Van Antwerp D., Mercurio F., Lee K.F., and Verma I.M. Severe liver degeneration in mice lacking the IkappaB kinase 2 gene. Science 284 (1999) 321-325
    • (1999) Science , vol.284 , pp. 321-325
    • Li, Q.1    Van Antwerp, D.2    Mercurio, F.3    Lee, K.F.4    Verma, I.M.5
  • 96
    • 0029059060 scopus 로고
    • Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-kappa B
    • Beg A.A., Sha W.C., Bronson R.T., Ghosh S., and Baltimore D. Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-kappa B. Nature 376 (1995) 167-170
    • (1995) Nature , vol.376 , pp. 167-170
    • Beg, A.A.1    Sha, W.C.2    Bronson, R.T.3    Ghosh, S.4    Baltimore, D.5
  • 97
    • 0027242180 scopus 로고
    • c-jun is essential for normal mouse development and hepatogenesis
    • Hilberg F., Aguzzi A., Howells N., and Wagner E.F. c-jun is essential for normal mouse development and hepatogenesis. Nature 365 (1993) 179-181
    • (1993) Nature , vol.365 , pp. 179-181
    • Hilberg, F.1    Aguzzi, A.2    Howells, N.3    Wagner, E.F.4
  • 98
    • 11244303498 scopus 로고    scopus 로고
    • Weapons of STAT destruction interferon evasion by paramyxovirus V protein
    • Horvath C.M. Weapons of STAT destruction interferon evasion by paramyxovirus V protein. Eur J Biochem 271 (2004) 4621-4628
    • (2004) Eur J Biochem , vol.271 , pp. 4621-4628
    • Horvath, C.M.1


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