메뉴 건너뛰기




Volumn 13, Issue 2, 2012, Pages 2219-2238

Alpha7 nicotinic acetylcholine receptor is a target in pharmacology and toxicology

Author keywords

Agonist; Alzheimer's disease; Antagonist; Cholinergic anti inflammatory pathway; Cognitive disorder; Inflammation; Schizophrenia

Indexed keywords

1 (5 CHLORO 2,4 DIMETHOXYPHENYL) 3 (5 METHYLISOXAZOL 3 YL)UREA; 1 [6 (4 FLUOROPHENYL)PYRIDIN 3 YL] 3 (4 PIPERIDIN 1 YLBUTYL)UREA; 2'H SPIRO(4 AZABICYCLO[2.2.2]OCTANE 2,5' [1,3]OXAZOLIDIN) 2' ONE; 3 (2,4 DIMETHOXYBENZYLIDENE)ANABASEINE; 5 (6 [1 AZABICYCLO[2.2.2]OCT 3 YLOXY]PYRIDAZIN 3 YL) 1H INDOLE; 5 MORPHOLIN 4 YL PENTANOIC ACID (4 PYRIDIN 3 YL PHENYL)AMIDE; ABT 107; ALPHA BUNGAROTOXIN; ATROPINE; AZD 0328; BUNGAROTOXIN RECEPTOR; BUNGAROTOXIN RECEPTOR AGONIST; BUNGAROTOXIN RECEPTOR ANTAGONIST; CHOLINERGIC RECEPTOR; CHOLINERGIC RECEPTOR STIMULATING AGENT; CLOZAPINE; CONOTOXIN; LEONEX; MECAMYLAMINE; MEMANTINE; METHYLLYCACONITINE; N (1 AZABICYCLO[2.2.2]OCT 3 YL) 1H INDAZOLE 3 CARBOXAMIDE; N [2 (PYRIDIN 3 YLMETHYL) 1 AZABICYCLO[2.2.2]OCT 3 YL] 1 BENZOFURAN 2 CARBOXAMIDE; NICOTINIC AGENT; NICOTINIC RECEPTOR BLOCKING AGENT; PNU 120596; RG 3487; SCOPOLAMINE; SEMAPIMOD; SEN 12333; SEN 34625; SPIRO[1 AZABICYCLO[2.2.2]OCTANE 3,2' THIAZOLIDINE] 2' ONE; TC 5214; TC 5619; UNCLASSIFIED DRUG; WYE 103914; ACETYLCHOLINE; ALPHA7 NICOTINIC ACETYLCHOLINE RECEPTOR; ANTI-INFLAMMATORY AGENTS; ASOXIME CHLORIDE; EXCITATORY AMINO ACID AGONISTS; EXCITATORY AMINO ACID ANTAGONISTS; OXIMES; PYRIDINIUM COMPOUNDS;

EID: 84857663983     PISSN: None     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms13022219     Document Type: Review
Times cited : (155)

References (117)
  • 1
    • 38449111281 scopus 로고    scopus 로고
    • Acetylcholine
    • doi:10.1895/wormbook.1.131.1. Available online, accessed on 17 February 2012
    • Rand, J.B. Acetylcholine. WormBook 2007, doi:10.1895/wormbook.1.131.1. Available online: http://www.wormbook.org (accessed on 17 February 2012).
    • WormBook 2007
    • Rand, J.B.1
  • 2
    • 10444252700 scopus 로고
    • Uberhumerole ubertragbarkeit der herznervenwirkung
    • Loewi, O. Uberhumerole ubertragbarkeit der herznervenwirkung. I. Mitt. Pflugers Arch. 1921, 189, 239-242.
    • (1921) I. Mitt. Pflugers Arch , vol.189 , pp. 239-242
    • Loewi, O.1
  • 3
    • 49449094458 scopus 로고    scopus 로고
    • Acetylcholine beyond neurons: The non-neuronal cholinergic system in humans
    • Wessler, I.; Kirkpatrick, C.J. Acetylcholine beyond neurons: The non-neuronal cholinergic system in humans. Br. J. Pharmacol. 2008, 154, 1558-1571.
    • (2008) Br. J. Pharmacol , vol.154 , pp. 1558-1571
    • Wessler, I.1    Kirkpatrick, C.J.2
  • 4
    • 0037375478 scopus 로고    scopus 로고
    • Cytosolic choline acetyltransferase binds specifically to cholinergic plasma membrane of rat brain synaptosomes to generate membrane-bound enzyme
    • Gabrielle, P.; Jeana, M.; Lorenza, E.C. Cytosolic choline acetyltransferase binds specifically to cholinergic plasma membrane of rat brain synaptosomes to generate membrane-bound enzyme. Neurochem. Res. 2003, 28, 543-549.
    • (2003) Neurochem. Res , vol.28 , pp. 543-549
    • Gabrielle, P.1    Jeana, M.2    Lorenza, E.C.3
  • 5
    • 33846660370 scopus 로고    scopus 로고
    • Acetylcholine release from the central nervous system: A 50year retrospective
    • Phillis, J.W. Acetylcholine release from the central nervous system: A 50year retrospective. Crit. Rev. Neurobiol. 2005, 17, 161-217.
    • (2005) Crit. Rev. Neurobiol , vol.17 , pp. 161-217
    • Phillis, J.W.1
  • 6
    • 0029122830 scopus 로고
    • Synaptic like microvesicles: Do they participate in regulated exocytosis?
    • Llona, I. Synaptic like microvesicles: Do they participate in regulated exocytosis? Neurochem. Int. 1995, 27, 219-226.
    • (1995) Neurochem. Int , vol.27 , pp. 219-226
    • Llona, I.1
  • 9
    • 3042673717 scopus 로고    scopus 로고
    • Expression and localization of acetylcholinesterase at the neuromuscular junction
    • Rotundo, R.L. Expression and localization of acetylcholinesterase at the neuromuscular junction. J. Neurocytol. 2003, 32, 743-766.
    • (2003) J. Neurocytol , vol.32 , pp. 743-766
    • Rotundo, R.L.1
  • 10
    • 11144243802 scopus 로고    scopus 로고
    • Choline transporters, cholinergic transmission and cognition
    • Sarter, M.; Parikh, V. Choline transporters, cholinergic transmission and cognition. Nat. Rev. Neurosci. 2005, 6, 48-56.
    • (2005) Nat. Rev. Neurosci , vol.6 , pp. 48-56
    • Sarter, M.1    Parikh, V.2
  • 11
    • 0021990059 scopus 로고
    • Isolation of an organism resembling Clostridium baratii which produces type F botulinal toxon from an infant with botulism
    • Hall, J.D.; McCroskey, L.M.; Pincomb, B.J.; Hatheway, C.L. Isolation of an organism resembling Clostridium baratii which produces type F botulinal toxon from an infant with botulism. J. Clin. Microbiol. 1985, 21, 654-655.
    • (1985) J. Clin. Microbiol , vol.21 , pp. 654-655
    • Hall, J.D.1    McCroskey, L.M.2    Pincomb, B.J.3    Hatheway, C.L.4
  • 13
    • 0031712779 scopus 로고    scopus 로고
    • Crystal structure of botulinum neurotoxin type A and implications for toxicity
    • Lacy, D.B.; Tepp, W.; Cohen, A.C.; DasGupta, B.R.; Stevens, R.C. Crystal structure of botulinum neurotoxin type A and implications for toxicity. Nat. Struct. Biol. 1998, 5, 898-902.
    • (1998) Nat. Struct. Biol , vol.5 , pp. 898-902
    • Lacy, D.B.1    Tepp, W.2    Cohen, A.C.3    Dasgupta, B.R.4    Stevens, R.C.5
  • 14
    • 33747188659 scopus 로고    scopus 로고
    • Botulinum neurotoxin structure, engineering, and novel cellular trafficking and targeting
    • Singh, B.R. Botulinum neurotoxin structure, engineering, and novel cellular trafficking and targeting. Neurotox. Res. 2006, 9, 73-92.
    • (2006) Neurotox. Res , vol.9 , pp. 73-92
    • Singh, B.R.1
  • 15
    • 84857669704 scopus 로고    scopus 로고
    • A quick guide to muscarinic acetylcholine receptors
    • Hirota, S.A. A quick guide to muscarinic acetylcholine receptors. BioPharm. J. 2001, 5, 6-8.
    • (2001) BioPharm. J , vol.5 , pp. 6-8
    • Hirota, S.A.1
  • 16
    • 0029013930 scopus 로고
    • Muscarinic acetylcholine receptors: Signal transduction through multiple effectors
    • Felder, C.C. Muscarinic acetylcholine receptors: Signal transduction through multiple effectors. FASEB J. 1995, 9, 619-625.
    • (1995) FASEB J , vol.9 , pp. 619-625
    • Felder, C.C.1
  • 17
    • 65949103174 scopus 로고    scopus 로고
    • Muscarinic receptor subtypes in the alimentary track
    • Tobin, G.; Giglio, D.; Lundgren, O. Muscarinic receptor subtypes in the alimentary track. J. Physiol. Pharmacol. 2009, 60, 3-21.
    • (2009) J. Physiol. Pharmacol , vol.60 , pp. 3-21
    • Tobin, G.1    Giglio, D.2    Lundgren, O.3
  • 18
    • 0026722913 scopus 로고
    • Reconstitution of agonist-stimulated phoshpatidylinostiol 4,5-bisphosphate hydrolysis using purified m1 muscarinic receptor, Gq/11 and phospholipase C-β1
    • Berstein, G.; Blank, J.L.; Smrcka, A.; Higashijima, T.; Sternweis, P.C.; Exton, J.H.; Ross, E.M. Reconstitution of agonist-stimulated phoshpatidylinostiol 4,5-bisphosphate hydrolysis using purified m1 muscarinic receptor, Gq/11 and phospholipase C-β1. J. Biol. Chem. 1992, 267, 8081-8088.
    • (1992) J. Biol. Chem , vol.267 , pp. 8081-8088
    • Berstein, G.1    Blank, J.L.2    Smrcka, A.3    Higashijima, T.4    Sternweis, P.C.5    Exton, J.H.6    Ross, E.M.7
  • 19
    • 75749117137 scopus 로고    scopus 로고
    • Kinetics of M1 muscarinic receptor and G protein signaling to phospholipase C in living cells
    • Falkenburger, B.H.; Jensen, J.B.; Hille, B. Kinetics of M1 muscarinic receptor and G protein signaling to phospholipase C in living cells. J. Gen. Physiol. 2010, 135, 81-97.
    • (2010) J. Gen. Physiol , vol.135 , pp. 81-97
    • Falkenburger, B.H.1    Jensen, J.B.2    Hille, B.3
  • 20
    • 0026086012 scopus 로고
    • Reconstitutively active G protein-coupled receptors purified from baculovirus-infected insect cells
    • Parker, E.M.; Kameyama, K.; Higashijima, T.; Ross, E.M. Reconstitutively active G protein-coupled receptors purified from baculovirus-infected insect cells. J. Biol. Chem. 1991, 266, 519-527.
    • (1991) J. Biol. Chem , vol.266 , pp. 519-527
    • Parker, E.M.1    Kameyama, K.2    Higashijima, T.3    Ross, E.M.4
  • 22
    • 33745601086 scopus 로고    scopus 로고
    • Bradycardia and hypotension refractory to ephedrine and atropine treatment: Severe autonomic dysfunction with abnormal heart rate variability
    • Horng, H.C.; Chen, F.C.; Ho, C.C.; Kuo, C.P.; Wu, C.T.; Wong, C.S. Bradycardia and hypotension refractory to ephedrine and atropine treatment: Severe autonomic dysfunction with abnormal heart rate variability. Acta Anaesthesiol. Taiwan 2006, 44, 109-112.
    • (2006) Acta Anaesthesiol. Taiwan , vol.44 , pp. 109-112
    • Horng, H.C.1    Chen, F.C.2    Ho, C.C.3    Kuo, C.P.4    Wu, C.T.5    Wong, C.S.6
  • 23
    • 33947502555 scopus 로고    scopus 로고
    • Pretreating rats with parenteral ophthalmic antimuscarinic agents decreases mortality from lethal organophosphate poisoning
    • Bryant, S.M.; Rhee, J.W.; Thompson, T.M.; Aks, S.E. Pretreating rats with parenteral ophthalmic antimuscarinic agents decreases mortality from lethal organophosphate poisoning. Acad. Emerg. Med. 2007, 14, 370-372.
    • (2007) Acad. Emerg. Med , vol.14 , pp. 370-372
    • Bryant, S.M.1    Rhee, J.W.2    Thompson, T.M.3    Aks, S.E.4
  • 24
    • 33745879783 scopus 로고    scopus 로고
    • Transdermal scopolamine for prevention of motion sickness: Clinical pharmacokinetics and therapeutic applications
    • Nachum, Z.; Shupak, A.; Gordon, C.R. Transdermal scopolamine for prevention of motion sickness: Clinical pharmacokinetics and therapeutic applications. Clin. Pharmacokinet. 2006, 45, 543-566.
    • (2006) Clin. Pharmacokinet , vol.45 , pp. 543-566
    • Nachum, Z.1    Shupak, A.2    Gordon, C.R.3
  • 26
    • 58249122324 scopus 로고    scopus 로고
    • Attenuation of amphetamine-induced activity by the non-selective muscarinic receptor agonist, xanomeline, is absent in muscarinic M4 receptor knockout mice and attenuated in muscarinic M1 redceptor knockout mice
    • Woolley, M.L.; Carter, H.J.; Gartlon, J.E.; Watson, J.M.; Dawson, L.A. Attenuation of amphetamine-induced activity by the non-selective muscarinic receptor agonist, xanomeline, is absent in muscarinic M4 receptor knockout mice and attenuated in muscarinic M1 redceptor knockout mice. Eur. J. Pharmacol. 2009, 603, 147-149.
    • (2009) Eur. J. Pharmacol , vol.603 , pp. 147-149
    • Woolley, M.L.1    Carter, H.J.2    Gartlon, J.E.3    Watson, J.M.4    Dawson, L.A.5
  • 27
    • 60249093377 scopus 로고    scopus 로고
    • Muscarinic agonists for the treatment of cognition in schizophrenia
    • Sellin, A.K.; Shad, M.; Tamminga, C. Muscarinic agonists for the treatment of cognition in schizophrenia. CNS Spectr. 2008, 13, 985-996.
    • (2008) CNS Spectr , vol.13 , pp. 985-996
    • Sellin, A.K.1    Shad, M.2    Tamminga, C.3
  • 28
    • 33745643582 scopus 로고    scopus 로고
    • Differential effects of the muscarinic M1 receptor agonist RS-86 and the acetylcholine-esterase inhibitor donepezil on REM sleep regulation in healthy volunteers
    • Nissen, C.; Nofzinger, E.A.; Feige, B.; Waldheim, B.; Radosa, M.P.; Riemann, D.; Berger, M. Differential effects of the muscarinic M1 receptor agonist RS-86 and the acetylcholine-esterase inhibitor donepezil on REM sleep regulation in healthy volunteers. Neuropsychopharmacology 2006, 31, 1294-1300.
    • (2006) Neuropsychopharmacology , vol.31 , pp. 1294-1300
    • Nissen, C.1    Nofzinger, E.A.2    Feige, B.3    Waldheim, B.4    Radosa, M.P.5    Riemann, D.6    Berger, M.7
  • 29
    • 76649095277 scopus 로고    scopus 로고
    • Why do patients with schizophrenia smoke
    • Winterer, G. Why do patients with schizophrenia smoke. Curr. Opin. Psychiatry 2010, 23, 112-119.
    • (2010) Curr. Opin. Psychiatry , vol.23 , pp. 112-119
    • Winterer, G.1
  • 30
    • 58249093913 scopus 로고    scopus 로고
    • Use of caffeine and nicotine in people with schizophrenia
    • Williams, J.M.; Gandhi, K.K. Use of caffeine and nicotine in people with schizophrenia. Curr. Drug Abuse Rev. 2008, 1, 155-161.
    • (2008) Curr. Drug Abuse Rev , vol.1 , pp. 155-161
    • Williams, J.M.1    Gandhi, K.K.2
  • 31
    • 0037134292 scopus 로고    scopus 로고
    • The levels of norharman are high enough after smoking to affect monoamineoxidase B in platelets
    • Rommelspacher, H.; Meier-Henco, M.; Smolka, M.; Kloft, C. The levels of norharman are high enough after smoking to affect monoamineoxidase B in platelets. Eur. J. Pharmacol. 2002, 441, 115-125.
    • (2002) Eur. J. Pharmacol , vol.441 , pp. 115-125
    • Rommelspacher, H.1    Meier-Henco, M.2    Smolka, M.3    Kloft, C.4
  • 32
    • 79953236096 scopus 로고    scopus 로고
    • From toxins targeting ligand gated ion channels to therapeutic molecules
    • Nasiripourdori, A.; Taly, V.; Grutter, T.; Taly, A. From toxins targeting ligand gated ion channels to therapeutic molecules. Toxins 2011, 3, 260-293.
    • (2011) Toxins , vol.3 , pp. 260-293
    • Nasiripourdori, A.1    Taly, V.2    Grutter, T.3    Taly, A.4
  • 33
    • 33846817498 scopus 로고    scopus 로고
    • Physiology and immunolgy of the cholinergic antiinflammatory pathway
    • Tracey, K.J. Physiology and immunolgy of the cholinergic antiinflammatory pathway. J. Clin. Invest. 2007, 117, 289-296.
    • (2007) J. Clin. Invest , vol.117 , pp. 289-296
    • Tracey, K.J.1
  • 34
    • 68349146499 scopus 로고    scopus 로고
    • A review of experimental techniques used for the heterologous expression of nicotinic acetylcholine receptors
    • Millar, N.S. A review of experimental techniques used for the heterologous expression of nicotinic acetylcholine receptors. Biochem. Pharmacol. 2009, 78, 766-776.
    • (2009) Biochem. Pharmacol , vol.78 , pp. 766-776
    • Millar, N.S.1
  • 35
    • 0033987721 scopus 로고    scopus 로고
    • A comparative non-radioactive in situ hybridization and immunohistochemical study of the distribution of alpha7 and alpha8 subunits of the nicotinic acetylcholine receptors in visual areas of the chick brain
    • Lohmann, T.H.; Torrao, A.S.; Britto, L.R.; Lindstrom, J.; Hamassaki-Britto, D.E. A comparative non-radioactive in situ hybridization and immunohistochemical study of the distribution of alpha7 and alpha8 subunits of the nicotinic acetylcholine receptors in visual areas of the chick brain. Brain Res. 2000, 852, 463-469.
    • (2000) Brain Res , vol.852 , pp. 463-469
    • Lohmann, T.H.1    Torrao, A.S.2    Britto, L.R.3    Lindstrom, J.4    Hamassaki-Britto, D.E.5
  • 36
    • 13444271681 scopus 로고    scopus 로고
    • Refined Structure of the nicotinic acetylcholine receptor at 4 A resolution
    • Unwin, N. Refined Structure of the nicotinic acetylcholine receptor at 4 A resolution. J. Mol. Biol. 2005, 346, 967-989.
    • (2005) J. Mol. Biol , vol.346 , pp. 967-989
    • Unwin, N.1
  • 37
    • 58249113980 scopus 로고    scopus 로고
    • Mammalian nicotinic acetylcholine receptors: From structure to function
    • Albuquerque, E.X.; Pereira, E.F.; Alkondon, M.; Rogers, S.W. Mammalian nicotinic acetylcholine receptors: From structure to function. Physiol. Rev. 2009, 89, 73-120.
    • (2009) Physiol. Rev , vol.89 , pp. 73-120
    • Albuquerque, E.X.1    Pereira, E.F.2    Alkondon, M.3    Rogers, S.W.4
  • 38
    • 0031410384 scopus 로고    scopus 로고
    • Choline is a selective agonist of alpha7 nicotnic acetylcholine receptors in the rat brain neurons
    • Alkondon, M.; Pereira, E.F.R.; Cortes, W.S.; Maelicke, A.; Albuquerque, E.X. Choline is a selective agonist of alpha7 nicotnic acetylcholine receptors in the rat brain neurons. Eur. J. Neurosci. 1997, 9, 2734-2742.
    • (1997) Eur. J. Neurosci , vol.9 , pp. 2734-2742
    • Alkondon, M.1    Pereira, E.F.R.2    Cortes, W.S.3    Maelicke, A.4    Albuquerque, E.X.5
  • 40
    • 77949744982 scopus 로고    scopus 로고
    • Cholinergic modulation of neuronal excitability in the rat suprachiasmatic nucleus
    • Yang, J.J.; Wang, Y.T.; Cheng, P.C.; Kuo, Y.J.; Huang, R.C. Cholinergic modulation of neuronal excitability in the rat suprachiasmatic nucleus. J. Neurophysiol. 2010, 103, 1397-1409.
    • (2010) J. Neurophysiol , vol.103 , pp. 1397-1409
    • Yang, J.J.1    Wang, Y.T.2    Cheng, P.C.3    Kuo, Y.J.4    Huang, R.C.5
  • 41
    • 0033119869 scopus 로고    scopus 로고
    • Mutational analysis of the charge selectivity filter of the α7 nicotinic acetylcholine receptor
    • Corringer, P.J.; Bertrand, S.; Galzi, J.L.; Devillers-Thiery, A.; Changeux, J.P.; Bertrand, D. Mutational analysis of the charge selectivity filter of the α7 nicotinic acetylcholine receptor. Neuron 1999, 22, 831-843.
    • (1999) Neuron , vol.22 , pp. 831-843
    • Corringer, P.J.1    Bertrand, S.2    Galzi, J.L.3    Devillers-Thiery, A.4    Changeux, J.P.5    Bertrand, D.6
  • 42
    • 68949212896 scopus 로고    scopus 로고
    • Protein complexes in snake venom
    • Doley, R.; Kini, R.M. Protein complexes in snake venom. Cell. Mol. Life Sci. 2009, 66, 2851-2871.
    • (2009) Cell. Mol. Life Sci , vol.66 , pp. 2851-2871
    • Doley, R.1    Kini, R.M.2
  • 43
    • 70349568132 scopus 로고    scopus 로고
    • Malignant hyperthermia and muscular dystrophies
    • Gurnaney, H.; Brown, A.; Litman, R.S. Malignant hyperthermia and muscular dystrophies. Anesth. Anal. 2009, 109, 1043-1048.
    • (2009) Anesth. Anal , vol.109 , pp. 1043-1048
    • Gurnaney, H.1    Brown, A.2    Litman, R.S.3
  • 45
    • 37349055746 scopus 로고    scopus 로고
    • Two novel mutations in the BChE gene in patients with prolonged duration of action of mivacurium or succinylcholine during anaesthesia
    • Gatke, M.R.; Bundgaard, J.R.; Viby-Mogensen, J. Two novel mutations in the BChE gene in patients with prolonged duration of action of mivacurium or succinylcholine during anaesthesia. Pharmacogenet. Genomics 2007, 17, 995-999.
    • (2007) Pharmacogenet. Genomics , vol.17 , pp. 995-999
    • Gatke, M.R.1    Bundgaard, J.R.2    Viby-Mogensen, J.3
  • 46
    • 67349209574 scopus 로고    scopus 로고
    • A cog in cognition: How the alpha 7 nicotinic acetylcholine receptor is geared towards improving cognitive deficits
    • Leiser, S.C.; Bowlby, M.R.; Comery, T.A.; Dunlop, J. A cog in cognition: How the alpha 7 nicotinic acetylcholine receptor is geared towards improving cognitive deficits. Pharmacol. Ther. 2009, 122, 302-311.
    • (2009) Pharmacol. Ther , vol.122 , pp. 302-311
    • Leiser, S.C.1    Bowlby, M.R.2    Comery, T.A.3    Dunlop, J.4
  • 47
    • 78650521407 scopus 로고    scopus 로고
    • Activation of nicotinic α(7) acetylcholine receptor enhances long term potentation in wild type mice but not in APP (swe)/PS1ΔE9 mice
    • Soderman, A.; Mikkelsen, J.D.; West, M.J.; Christensen, D.Z.; Jensen, M.S. Activation of nicotinic α(7) acetylcholine receptor enhances long term potentation in wild type mice but not in APP (swe)/PS1ΔE9 mice. Neurosci. Lett. 2011, 487, 325-329.
    • (2011) Neurosci. Lett , vol.487 , pp. 325-329
    • Soderman, A.1    Mikkelsen, J.D.2    West, M.J.3    Christensen, D.Z.4    Jensen, M.S.5
  • 48
    • 77949462775 scopus 로고    scopus 로고
    • Cognitive improvement by activation of alpha7 nicotinic acetylcholine receptors: From animal models to human pathophysiology
    • Thomsen, M.S.; Hansen, H.H.; Timmerman, D.B.; Kikkelsen, J.D. Cognitive improvement by activation of alpha7 nicotinic acetylcholine receptors: From animal models to human pathophysiology. Curr. Pharm. Des. 2010, 16, 323-343.
    • (2010) Curr. Pharm. Des , vol.16 , pp. 323-343
    • Thomsen, M.S.1    Hansen, H.H.2    Timmerman, D.B.3    Kikkelsen, J.D.4
  • 49
    • 67651208215 scopus 로고    scopus 로고
    • Association between a genetic variant of the alpha-7 nicotinic acetylcholine receptor subunit and four types of dementia
    • Feher, A.; Juhasz, A.; Rimanoczy, A.; Csibri, E.; Kalman, J.; Janka, Z. Association between a genetic variant of the alpha-7 nicotinic acetylcholine receptor subunit and four types of dementia. Dement. Geriatr. Cogn. Disord. 2009, 28, 56-62.
    • (2009) Dement. Geriatr. Cogn. Disord , vol.28 , pp. 56-62
    • Feher, A.1    Juhasz, A.2    Rimanoczy, A.3    Csibri, E.4    Kalman, J.5    Janka, Z.6
  • 50
    • 20644443926 scopus 로고    scopus 로고
    • Increased alpha 7 nicotinic acetylcholine receptor protein levels in Alzheimer's disease patients
    • Chu, L.W.; Ma, E.S.; Lam, K.K.; Chan, M.F.; Lee, D.H. Increased alpha 7 nicotinic acetylcholine receptor protein levels in Alzheimer's disease patients. Dement. Geriatr. Cogn. Disord. 2005, 19, 106-112.
    • (2005) Dement. Geriatr. Cogn. Disord , vol.19 , pp. 106-112
    • Chu, L.W.1    Ma, E.S.2    Lam, K.K.3    Chan, M.F.4    Lee, D.H.5
  • 52
    • 59149084166 scopus 로고    scopus 로고
    • Alpha7 and non-alpha7 nicotinic acetylcholine receptors modulate dopamine release in vitro and in vivo in the rat prefrontal cortex
    • Livingston, P.D.; Srinivasan, J.; Kew, J.N.; Dawson, L.A.; Gotti, C.; Moretti, M.; Shoaib, M.; Wonnacott, S. Alpha7 and non-alpha7 nicotinic acetylcholine receptors modulate dopamine release in vitro and in vivo in the rat prefrontal cortex. Eur. J. Neurosci. 2009, 29, 539-550.
    • (2009) Eur. J. Neurosci , vol.29 , pp. 539-550
    • Livingston, P.D.1    Srinivasan, J.2    Kew, J.N.3    Dawson, L.A.4    Gotti, C.5    Moretti, M.6    Shoaib, M.7    Wonnacott, S.8
  • 53
    • 3142761435 scopus 로고    scopus 로고
    • Alpha-7 nicotinic receptor agonists: Potential new candidates for the treatment of schizophrenia
    • Martin, L.F.; Kem, W.R.; Freedman, R. Alpha-7 nicotinic receptor agonists: Potential new candidates for the treatment of schizophrenia. Psychopharmacology 2004, 174, 54-64.
    • (2004) Psychopharmacology , vol.174 , pp. 54-64
    • Martin, L.F.1    Kem, W.R.2    Freedman, R.3
  • 54
    • 0035726679 scopus 로고    scopus 로고
    • Neuronal nicotinic acetylcholine receptor subunit knockout mice: Physiological and behavioral phenotypes and possible clinical inplications
    • Picciotto, M.R.; Caldarone, B.J.; Brunzell, D.H.; Zachariou, V.; Stevens, T.R.; King, S.L. Neuronal nicotinic acetylcholine receptor subunit knockout mice: Physiological and behavioral phenotypes and possible clinical inplications. Pharmacol. Ther. 2001, 92, 89-108.
    • (2001) Pharmacol. Ther , vol.92 , pp. 89-108
    • Picciotto, M.R.1    Caldarone, B.J.2    Brunzell, D.H.3    Zachariou, V.4    Stevens, T.R.5    King, S.L.6
  • 55
    • 67650484613 scopus 로고    scopus 로고
    • Deletion of the alpha 7 nicotinic acetylcholine receptor gene improves cognitive deficits and synaptic pathology in a mouse model of Alzheimer's disease
    • Dziewczapolski, G.; Glogowski, C.M.; Masliah, E.; Heinemann, S.F. Deletion of the alpha 7 nicotinic acetylcholine receptor gene improves cognitive deficits and synaptic pathology in a mouse model of Alzheimer's disease. J. Neurosci. 2009, 29, 8805-8815.
    • (2009) J. Neurosci , vol.29 , pp. 8805-8815
    • Dziewczapolski, G.1    Glogowski, C.M.2    Masliah, E.3    Heinemann, S.F.4
  • 57
    • 0037180778 scopus 로고    scopus 로고
    • The inflammatory reflex
    • Tracey, K.J. The inflammatory reflex. Nature 2002, 420, 853-859.
    • (2002) Nature , vol.420 , pp. 853-859
    • Tracey, K.J.1
  • 59
    • 66449111088 scopus 로고    scopus 로고
    • Reflex control of immunity
    • Tracey, K.J. Reflex control of immunity. Nat. Rev. Immunol. 2009, 9, 418-428.
    • (2009) Nat. Rev. Immunol , vol.9 , pp. 418-428
    • Tracey, K.J.1
  • 60
    • 26844443550 scopus 로고    scopus 로고
    • Fat meets the cholinergic antiinflammatory pathway
    • 1071-1021
    • Tracey, K.J. Fat meets the cholinergic antiinflammatory pathway. J. Exp. Med. 2005, 202, 1071-1021.
    • (2005) J. Exp. Med , vol.202
    • Tracey, K.J.1
  • 61
    • 79952279972 scopus 로고    scopus 로고
    • Implementing a collaborative protocol in a sepsis intervention program: Lessons learned
    • Casserly, B.; Baram, M.; Walsh, P.; Sucov, A.; Ward, N.S. Levy, M.M. Implementing a collaborative protocol in a sepsis intervention program: Lessons learned. Lung 2011, 189, 11-19.
    • (2011) Lung , vol.189 , pp. 11-19
    • Casserly, B.1    Baram, M.2    Walsh, P.3    Sucov, A.4    Ward, N.S.5    Levy, M.M.6
  • 62
    • 0034714215 scopus 로고    scopus 로고
    • Macrophage lipoprotein lipase promotes foam cell formation and atherosclerosis in low density lipoprotein receptor-deficient mice
    • Babaev, V.R.; Patel, M.B.; Semenkovich, C.F.; Fazio, S.; Linton, M.F. Macrophage lipoprotein lipase promotes foam cell formation and atherosclerosis in low density lipoprotein receptor-deficient mice. J. Biol. Chem. 2000, 275, 26293-26299.
    • (2000) J. Biol. Chem , vol.275 , pp. 26293-26299
    • Babaev, V.R.1    Patel, M.B.2    Semenkovich, C.F.3    Fazio, S.4    Linton, M.F.5
  • 64
    • 79851491493 scopus 로고    scopus 로고
    • Macrophage-assisted inflammation and pharmacological regulation of the cholinergic anti-inflammatory pathway
    • Pohanka, M.; Snopkova, S.; Havlickova, K.; Bostik, P.; Sinkorova, Z.; Fusek, J.; Kuca, K.; Pikula, J. Macrophage-assisted inflammation and pharmacological regulation of the cholinergic anti-inflammatory pathway. Curr. Med. Chem. 2011, 18, 539-551.
    • (2011) Curr. Med. Chem , vol.18 , pp. 539-551
    • Pohanka, M.1    Snopkova, S.2    Havlickova, K.3    Bostik, P.4    Sinkorova, Z.5    Fusek, J.6    Kuca, K.7    Pikula, J.8
  • 65
    • 56649095996 scopus 로고    scopus 로고
    • Experimental therapeutic strategies for severe sepsis: Mediators and mechanisms
    • Parrish, W.R.; Gallowitsch-Puerta, M.; Czura, C.J.; Tracey, K.J. Experimental therapeutic strategies for severe sepsis: Mediators and mechanisms. Ann. N. Y. Acad. Sci. 2008, 1144, 210-236.
    • (2008) Ann. N. Y. Acad. Sci , vol.1144 , pp. 210-236
    • Parrish, W.R.1    Gallowitsch-Puerta, M.2    Czura, C.J.3    Tracey, K.J.4
  • 66
    • 78149272143 scopus 로고    scopus 로고
    • Cholinergic anti-inflammatory pathway: A possible approach to protect against myocardial ischemia reperfusion injury
    • Xiong, J.; Xue, F.S.; Yuan, Y.J.; Wang, Q.; Liao, X.; Wang, W.L. Cholinergic anti-inflammatory pathway: A possible approach to protect against myocardial ischemia reperfusion injury. Chin. Med. J. (Engl.) 2010, 123, 2720-2726.
    • (2010) Chin. Med. J. (Engl.) , vol.123 , pp. 2720-2726
    • Xiong, J.1    Xue, F.S.2    Yuan, Y.J.3    Wang, Q.4    Liao, X.5    Wang, W.L.6
  • 67
    • 84857122448 scopus 로고    scopus 로고
    • Nicotine inhibits tumor necrosis factor-alpha induced IL-6 and IL-8 secretion in fibroblast-like synoviocytes from patients with rheumatoid arthritis
    • Zhou, Y.; Zuo, X.; Li, Y.; Wang, Y.; Zhao, H.; Xiao, X. Nicotine inhibits tumor necrosis factor-alpha induced IL-6 and IL-8 secretion in fibroblast-like synoviocytes from patients with rheumatoid arthritis. Rheumatol. Int. 2012, 32, 97-104.
    • (2012) Rheumatol. Int , vol.32 , pp. 97-104
    • Zhou, Y.1    Zuo, X.2    Li, Y.3    Wang, Y.4    Zhao, H.5    Xiao, X.6
  • 68
    • 67649133580 scopus 로고    scopus 로고
    • Alpha-conotoxins as pharmacological probes of nicotinic acetylholine receptors
    • Azam, L.; Mcintosh, J.M. Alpha-conotoxins as pharmacological probes of nicotinic acetylholine receptors. Acta Pharmacol. Sin. 2009, 30, 771-783.
    • (2009) Acta Pharmacol. Sin , vol.30 , pp. 771-783
    • Azam, L.1    McIntosh, J.M.2
  • 69
    • 3042566993 scopus 로고    scopus 로고
    • Structure-activity relationships of alpha-conotoxins targeting neuronal nicotinic acetylcholine receptors
    • Millard, E.L.; Daly, N.L.; Craik, D.J. Structure-activity relationships of alpha-conotoxins targeting neuronal nicotinic acetylcholine receptors. Eur. J. Biochem. 2004, 271, 2320-2326.
    • (2004) Eur. J. Biochem , vol.271 , pp. 2320-2326
    • Millard, E.L.1    Daly, N.L.2    Craik, D.J.3
  • 70
    • 0033545910 scopus 로고    scopus 로고
    • Biochemical characterization and nuclear magnetic resonance structure of novel alpha-conotoxins isolated from the venom of conus consors
    • Favreau, P.; Krimm, I.; Le Gall, F.; Bobenrieth, M.J.; Lamthanh, H.; Bouet, F.; Servent, D.; Molgo, J.; Menez, A.; Letouneux, Y. et al. Biochemical characterization and nuclear magnetic resonance structure of novel alpha-conotoxins isolated from the venom of conus consors. Biochemistry 1999, 38, 6317-6326.
    • (1999) Biochemistry , vol.38 , pp. 6317-6326
    • Favreau, P.1    Krimm, I.2    le Gall, F.3    Bobenrieth, M.J.4    Lamthanh, H.5    Bouet, F.6    Servent, D.7    Molgo, J.8    Menez, A.9    Letouneux, Y.10
  • 71
    • 0033579496 scopus 로고    scopus 로고
    • Single amino acid substitutions in alpha-conotoxin PnIA shift selectivity for subtypes of the mammalian neuronal nicotinic acetylcholine receptor
    • Hogg, R.C.; Miranda, L.P.; Craik, D.J.; Lewis, R.J.; Alewood, P.F.; Adams, D.J. Single amino acid substitutions in alpha-conotoxin PnIA shift selectivity for subtypes of the mammalian neuronal nicotinic acetylcholine receptor. J. Biol. Chem. 1999, 274, 36559-36564.
    • (1999) J. Biol. Chem , vol.274 , pp. 36559-36564
    • Hogg, R.C.1    Miranda, L.P.2    Craik, D.J.3    Lewis, R.J.4    Alewood, P.F.5    Adams, D.J.6
  • 72
    • 24044466131 scopus 로고    scopus 로고
    • Beta2 subunit contribution to 4/7 alpha-conotoxin binding to the nicotinic acetylchline receptor
    • Dutertre, S.; Nicke, A.; Lewis, R.J. Beta2 subunit contribution to 4/7 alpha-conotoxin binding to the nicotinic acetylchline receptor. J. Biol. Chem. 2005, 280, 30460-30468.
    • (2005) J. Biol. Chem , vol.280 , pp. 30460-30468
    • Dutertre, S.1    Nicke, A.2    Lewis, R.J.3
  • 74
    • 0033624918 scopus 로고    scopus 로고
    • 125I-alpha-conotoxin MII identifies a novel nicotinic acetylcholine receptor population in mouse brain
    • Whiteaker, P.; Mcintosh, J.M.; Luo, S.; Collins, A.C.; Marks, M.J. 125I-alpha-conotoxin MII identifies a novel nicotinic acetylcholine receptor population in mouse brain. Mol. Pharmacol. 2000, 57, 913-925.
    • (2000) Mol. Pharmacol , vol.57 , pp. 913-925
    • Whiteaker, P.1    McIntosh, J.M.2    Luo, S.3    Collins, A.C.4    Marks, M.J.5
  • 75
    • 0034212292 scopus 로고    scopus 로고
    • Localization of agonist and competitive antagonist binding sites on nicotinic acetylcholine receptors
    • Arias, H.R. Localization of agonist and competitive antagonist binding sites on nicotinic acetylcholine receptors. Neurochem. Int. 2000, 36, 595-645.
    • (2000) Neurochem. Int , vol.36 , pp. 595-645
    • Arias, H.R.1
  • 76
    • 33645511034 scopus 로고    scopus 로고
    • The cholinergic antagonist alpha-bungarotoxin also binds and blocks a subset of GABA receptors
    • McCann, C.M.; Bracamontes, J.; Steinbach, J.H.; Sanes, J.R. The cholinergic antagonist alpha-bungarotoxin also binds and blocks a subset of GABA receptors. Proc. Natl. Acad. Sci. USA 2006, 103, 5149-5154.
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 5149-5154
    • McCann, C.M.1    Bracamontes, J.2    Steinbach, J.H.3    Sanes, J.R.4
  • 77
    • 0032752898 scopus 로고    scopus 로고
    • Looking back on the discovery of alpha-bungarotoxin
    • Chang, C.C. Looking back on the discovery of alpha-bungarotoxin. J. Biomed. Sci. 1999, 6, 368-375.
    • (1999) J. Biomed. Sci , vol.6 , pp. 368-375
    • Chang, C.C.1
  • 78
    • 0035998347 scopus 로고    scopus 로고
    • Professor Chen-Yuan Lee, MD (1915-2001), pharmacologist: Snake venom research at the Institute of Pharmacology, National Taiwan University
    • Hawgood, B.J. Professor Chen-Yuan Lee, MD (1915-2001), pharmacologist: Snake venom research at the Institute of Pharmacology, National Taiwan University. Toxicon 2002, 40, 1065-1072.
    • (2002) Toxicon , vol.40 , pp. 1065-1072
    • Hawgood, B.J.1
  • 79
    • 21244504211 scopus 로고    scopus 로고
    • Contribution of a snake venom toxin to myasthenia gravis: The discovery of alpha-bungarotoxin in Taiwan
    • Chu, N.S. Contribution of a snake venom toxin to myasthenia gravis: The discovery of alpha-bungarotoxin in Taiwan. J. Hist. Neurosci. 2005, 14, 138-148.
    • (2005) J. Hist. Neurosci , vol.14 , pp. 138-148
    • Chu, N.S.1
  • 80
    • 14344253935 scopus 로고    scopus 로고
    • Memantine blocks alpha7* nicotnic acetylcholine receptors more potently than N-methyl-D-aspartate receptors in rat hippocampal neurons
    • Aracava, Y.; Pereira, E.F.; Maelicke, A.; Albuquerque, E.X. Memantine blocks alpha7* nicotnic acetylcholine receptors more potently than N-methyl-D-aspartate receptors in rat hippocampal neurons. J. Pharmacol. Exp. Ther. 2005, 312, 1195-1205.
    • (2005) J. Pharmacol. Exp. Ther , vol.312 , pp. 1195-1205
    • Aracava, Y.1    Pereira, E.F.2    Maelicke, A.3    Albuquerque, E.X.4
  • 81
    • 18044363484 scopus 로고    scopus 로고
    • Comments on "Memantine blocks alpha7* nicotnic acetylcholine receptors more potently than N-methyl-D-aspartate receptors in rat hippocampal neurons
    • Banerjee, P.; Samoriski, G.; Gupta, S. Comments on "Memantine blocks alpha7* nicotnic acetylcholine receptors more potently than N-methyl-D-aspartate receptors in rat hippocampal neurons". J. Pharmacol. Exp. Ther. 2005, 313, 928-929.
    • (2005) J. Pharmacol. Exp. Ther , vol.313 , pp. 928-929
    • Banerjee, P.1    Samoriski, G.2    Gupta, S.3
  • 82
    • 69949159308 scopus 로고    scopus 로고
    • Nicotinic receptors: Allosteric transitions and therapeutic targets in the nervous system
    • Taly, A.; Corringer, P.J.; Guedin, D.; Lestage, P.; Changeux, J.P. Nicotinic receptors: Allosteric transitions and therapeutic targets in the nervous system. Nat. Rev. Drug Discov. 2009, 8, 733-750.
    • (2009) Nat. Rev. Drug Discov , vol.8 , pp. 733-750
    • Taly, A.1    Corringer, P.J.2    Guedin, D.3    Lestage, P.4    Changeux, J.P.5
  • 83
    • 0036232874 scopus 로고    scopus 로고
    • The nicotinic allosteric potentiating ligand galantamine facilitates synaptic transmission in the mammalian central nervous system
    • Santos, M.D.; Alkondon, M.; Pereira, E.F.; Aracava, Y.; Eisenberg, H.M.; Maelicke, A.; Albuquerque, E.X. The nicotinic allosteric potentiating ligand galantamine facilitates synaptic transmission in the mammalian central nervous system. Mol. Pharmacol. 2002, 61, 1222-1234.
    • (2002) Mol. Pharmacol , vol.61 , pp. 1222-1234
    • Santos, M.D.1    Alkondon, M.2    Pereira, E.F.3    Aracava, Y.4    Eisenberg, H.M.5    Maelicke, A.6    Albuquerque, E.X.7
  • 85
    • 0036447187 scopus 로고    scopus 로고
    • Review of oximes in the antidotal treatment of poisoning by organophoshorus nerve agents
    • Kassa, J. Review of oximes in the antidotal treatment of poisoning by organophoshorus nerve agents. J. Toxicol. Clin. Toxicol. 2002, 40, 803-816.
    • (2002) J. Toxicol. Clin. Toxicol , vol.40 , pp. 803-816
    • Kassa, J.1
  • 86
    • 35648945420 scopus 로고    scopus 로고
    • Amperometric biosensor for evaluation of competitive cholinesterase inhibition by the reactivation HI-6
    • Pohanka, M.; Jun, D.; Kuca, K. Amperometric biosensor for evaluation of competitive cholinesterase inhibition by the reactivation HI-6. Anal. Lett. 2007, 40, 2351-2359.
    • (2007) Anal. Lett , vol.40 , pp. 2351-2359
    • Pohanka, M.1    Jun, D.2    Kuca, K.3
  • 88
    • 78650566267 scopus 로고    scopus 로고
    • Modulation of tularemia disease progress by the bisquaternary pyridinium oxime HI-6
    • Pohanka, M.; Pavlis, O.; Pikula, J.; Treml, F.; Kuca, K. Modulation of tularemia disease progress by the bisquaternary pyridinium oxime HI-6. Acta Vet. (Brno) 2010, 79, 443-448.
    • (2010) Acta Vet. (Brno) , vol.79 , pp. 443-448
    • Pohanka, M.1    Pavlis, O.2    Pikula, J.3    Treml, F.4    Kuca, K.5
  • 90
    • 12344273724 scopus 로고    scopus 로고
    • Small molecular drug transfer across the blood-brain barrier via carrier-mediated transport system
    • Tsuji, A. Small molecular drug transfer across the blood-brain barrier via carrier-mediated transport system. NeuroRx 2005, 2, 54-62.
    • (2005) NeuroRx , vol.2 , pp. 54-62
    • Tsuji, A.1
  • 91
    • 79955599163 scopus 로고    scopus 로고
    • Lipophilicity and its relationship with passive drug permeation
    • Liu, X.; Testa, B.; Fahr, A. Lipophilicity and its relationship with passive drug permeation. Pharm. Res. 2011, 28, 962-977.
    • (2011) Pharm. Res , vol.28 , pp. 962-977
    • Liu, X.1    Testa, B.2    Fahr, A.3
  • 92
    • 34547632714 scopus 로고    scopus 로고
    • Contribution of carrier-mediated transport system to the blood-brain barrier as a supporting and protecting interface for the brain, importance for CNS drug discovery and development
    • Ohtsuki, S.; Terasaki, T. Contribution of carrier-mediated transport system to the blood-brain barrier as a supporting and protecting interface for the brain, importance for CNS drug discovery and development. Pharm. Res. 2007, 24, 1745-1758.
    • (2007) Pharm. Res , vol.24 , pp. 1745-1758
    • Ohtsuki, S.1    Terasaki, T.2
  • 94
    • 77953219713 scopus 로고    scopus 로고
    • Novel alpha-7 nicotinic acetylcholine receptor agonists containing a urea moiety: Identification and characterization of the potent, selective, and orally efficacious agonist 1-[6-(4-fluorophenyl)pyridin-3-yl]-3-(4-piperidin-1-ylbutyl) urea (SEN34625/WYE-103914)
    • Chiron, C.; Haydar, S.N.; Aschmies, S.; Bothmann, H.; Castaldo, C.; Cocconcelli, G.; Comery, T.A.; Di, L.; Dunlop, J.; Lock, T. et al. Novel alpha-7 nicotinic acetylcholine receptor agonists containing a urea moiety: Identification and characterization of the potent, selective, and orally efficacious agonist 1-[6-(4-fluorophenyl)pyridin-3-yl]-3-(4-piperidin-1-ylbutyl) urea (SEN34625/WYE-103914). J. Med. Chem. 2010, 53, 4379-7389.
    • (2010) J. Med. Chem , vol.53 , pp. 4379-7389
    • Chiron, C.1    Haydar, S.N.2    Aschmies, S.3    Bothmann, H.4    Castaldo, C.5    Cocconcelli, G.6    Comery, T.A.7    Di, L.8    Dunlop, J.9    Lock, T.10
  • 95
    • 65649092520 scopus 로고    scopus 로고
    • Procognitive and neuroprotective activity of novel alpha 7 nicotinic acetylcholine receptor agonist for treatment of neurodegenerative and cognitive disorders
    • Roncarati, R.; Scali, C.; Comery, T.A.; Grauer, S.M.; Aschmi, S.; Bothmann, H.; Jow, B.; Kowal, D.; Gianfriddo, M.; Kelley, C. et al. Procognitive and neuroprotective activity of novel alpha 7 nicotinic acetylcholine receptor agonist for treatment of neurodegenerative and cognitive disorders. J. Pharmacol. Exp. Ther. 2009, 329, 459-468.
    • (2009) J. Pharmacol. Exp. Ther , vol.329 , pp. 459-468
    • Roncarati, R.1    Scali, C.2    Comery, T.A.3    Grauer, S.M.4    Aschmi, S.5    Bothmann, H.6    Jow, B.7    Kowal, D.8    Gianfriddo, M.9    Kelley, C.10
  • 98
    • 34548677767 scopus 로고    scopus 로고
    • Allosteric modulation of nicotinic acetlycholine receptors
    • Bertrand, D.; Gopalakrishnan, M. Allosteric modulation of nicotinic acetlycholine receptors. Biochem. Pharmacol. 2007, 74, 1155-1163.
    • (2007) Biochem. Pharmacol , vol.74 , pp. 1155-1163
    • Bertrand, D.1    Gopalakrishnan, M.2
  • 99
    • 78649735548 scopus 로고    scopus 로고
    • Activation of functional α7-containing nAChRs in hippocampal CA1 pyrmidal neurons by physiologica levels of choline in the presence of PNU-120596
    • doi:10.1371/journal.pone.0013964
    • Kalappa, B.I.; Gusev, A.G.; Uteshev, V.V. Activation of functional α7-containing nAChRs in hippocampal CA1 pyrmidal neurons by physiologica levels of choline in the presence of PNU-120596. PLoS One 2010, 5, doi:10.1371/journal.pone.0013964.
    • (2010) PLoS One , vol.5
    • Kalappa, B.I.1    Gusev, A.G.2    Uteshev, V.V.3
  • 101
    • 68349141525 scopus 로고    scopus 로고
    • Selective alpha7 nicotinic receptor activation by AZD0328 enhances cortical dopamine release and improves learning and attentional processes
    • Sydserff, S.; Sutton, E.J.; Song, D.; Quirk, M.C.; Maciag, C.; Li, C.; Jonak, G.; Gurley, D.; Gordon, J.C.; Christian, E.P. et al. Selective alpha7 nicotinic receptor activation by AZD0328 enhances cortical dopamine release and improves learning and attentional processes. Biochem. Pharmacol. 2009, 78, 880-888.
    • (2009) Biochem. Pharmacol , vol.78 , pp. 880-888
    • Sydserff, S.1    Sutton, E.J.2    Song, D.3    Quirk, M.C.4    Maciag, C.5    Li, C.6    Jonak, G.7    Gurley, D.8    Gordon, J.C.9    Christian, E.P.10
  • 102
    • 68349148342 scopus 로고    scopus 로고
    • TC-5619: An alpha7 neuronal nicotinic receptor-selective agonist that demonstrates efficacy in animal models of the positive and negative symptoms and cognitive dysfunction of schizophrenia
    • Hauser, T.A.; Kucinski, A.; Jordan, K.G.; Gatto, G.J.; Wersinger, S.R.; Hesse, R.A.; Stachowiak, E.K.; Stachowiak, M.K.; Papke, R.L.; Lippiello, P.M. et al. TC-5619: An alpha7 neuronal nicotinic receptor-selective agonist that demonstrates efficacy in animal models of the positive and negative symptoms and cognitive dysfunction of schizophrenia. Biochem. Pharmacol. 2009, 78, 803-812.
    • (2009) Biochem. Pharmacol , vol.78 , pp. 803-812
    • Hauser, T.A.1    Kucinski, A.2    Jordan, K.G.3    Gatto, G.J.4    Wersinger, S.R.5    Hesse, R.A.6    Stachowiak, E.K.7    Stachowiak, M.K.8    Papke, R.L.9    Lippiello, P.M.10
  • 103
    • 0037444897 scopus 로고    scopus 로고
    • Relative level of cytoprotection produced by analogs of choline and the role of alpha 7-nicotinic acetylcholine receptors
    • Jonnala, R.R.; Grahama, J.H.; Terry, A.V.; Beach, J.W.; Young, J.A.; Buccafusco, J.J. Relative level of cytoprotection produced by analogs of choline and the role of alpha 7-nicotinic acetylcholine receptors. Synapse 2003, 47, 262-269.
    • (2003) Synapse , vol.47 , pp. 262-269
    • Jonnala, R.R.1    Grahama, J.H.2    Terry, A.V.3    Beach, J.W.4    Young, J.A.5    Buccafusco, J.J.6
  • 104
    • 80054096801 scopus 로고    scopus 로고
    • Cholinesterases, a target of pharmacology and toxicology
    • Pohanka, M. Cholinesterases, a target of pharmacology and toxicology. Biomed. Pap. Olomouc 2011, 155, 219-223.
    • (2011) Biomed. Pap. Olomouc , vol.155 , pp. 219-223
    • Pohanka, M.1
  • 106
    • 66149103723 scopus 로고    scopus 로고
    • Cholinergic control of inflammation
    • Rosas-Ballina, M.; Tracey, K.J. Cholinergic control of inflammation. J. Intern. Med. 2009, 265, 663-679.
    • (2009) J. Intern. Med , vol.265 , pp. 663-679
    • Rosas-Ballina, M.1    Tracey, K.J.2
  • 107
    • 67650391166 scopus 로고    scopus 로고
    • The selective alpha7 agonist GTS-21 attenuates cytokine production in human whole blood and human monocytes activated by ligands for TLR2, TLR3, TLR4, TLR9, and RAGE
    • Rosas-Ballina, M.; Goldstein, R.S.; Gallowitsch-Puerta, M.; Yang, L.; Valdes-Ferrer, S.I.; Patel, N.B.; Chavan, S.; Al-Abed, Y.; Yang, H.; Tracey, K.J. The selective alpha7 agonist GTS-21 attenuates cytokine production in human whole blood and human monocytes activated by ligands for TLR2, TLR3, TLR4, TLR9, and RAGE. Mol. Med. 2009, 15, 195-202.
    • (2009) Mol. Med , vol.15 , pp. 195-202
    • Rosas-Ballina, M.1    Goldstein, R.S.2    Gallowitsch-Puerta, M.3    Yang, L.4    Valdes-Ferrer, S.I.5    Patel, N.B.6    Chavan, S.7    Al-Abed, Y.8    Yang, H.9    Tracey, K.J.10
  • 111
    • 33846961135 scopus 로고    scopus 로고
    • A novel inhibitor of inflammatory cytokine production (CNI-1493) reduces rodent post-hemorrhagic vasospasm
    • Bowman, G.; Bonneau, R.H.; Chinchilli, V.M.; Tracey, K.J.; Cockroft, K.M. A novel inhibitor of inflammatory cytokine production (CNI-1493) reduces rodent post-hemorrhagic vasospasm. Neurocit. Care 2006, 5, 222-229.
    • (2006) Neurocit. Care , vol.5 , pp. 222-229
    • Bowman, G.1    Bonneau, R.H.2    Chinchilli, V.M.3    Tracey, K.J.4    Cockroft, K.M.5
  • 112
    • 43349083457 scopus 로고    scopus 로고
    • From CNI-1493 to the immunological homunculus: Physiology of the inflammatory reflex
    • Oke, S.L.; Tracey, K.J. From CNI-1493 to the immunological homunculus: Physiology of the inflammatory reflex. J. Leukoc. Biol. 2008, 83, 512-517.
    • (2008) J. Leukoc. Biol , vol.83 , pp. 512-517
    • Oke, S.L.1    Tracey, K.J.2
  • 114
    • 77953170758 scopus 로고    scopus 로고
    • Synergism in survival to endotoxic shock in rats given microencapsulated CNI-1493 and antisense oligomers to NF-kappaB
    • Oettinger, C.W.; D'Souza, M.J. Synergism in survival to endotoxic shock in rats given microencapsulated CNI-1493 and antisense oligomers to NF-kappaB. J. Microencapsul. 2010, 27, 372-376.
    • (2010) J. Microencapsul , vol.27 , pp. 372-376
    • Oettinger, C.W.1    D'souza, M.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.