메뉴 건너뛰기




Volumn 5, Issue 11, 2010, Pages

Activation of functional α7-containing nAChRs in hippocampal CA1 pyramidal neurons by physiological levels of choline in the presence of PNU-120596

Author keywords

[No Author keywords available]

Indexed keywords

BUNGAROTOXIN RECEPTOR; CHOLINE; N (5 CHLORO 2,4 DIMETHOXYPHENYL) N (5 METHYL 3 ISOXAZOLYL)UREA; NICOTINIC RECEPTOR BLOCKING AGENT; PNU 120596; UNCLASSIFIED DRUG; 1 (5 CHLORO 2,4 DIMETHOXYPHENYL) 3 (5 METHYLISOXAZOL 3 YL)UREA; 1-(5-CHLORO-2,4-DIMETHOXYPHENYL)-3-(5-METHYLISOXAZOL-3-YL)UREA; CARBANILAMIDE DERIVATIVE; ISOXAZOLE DERIVATIVE; NICOTINIC RECEPTOR; NOOTROPIC AGENT;

EID: 78649735548     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0013964     Document Type: Article
Times cited : (35)

References (71)
  • 1
    • 70350446961 scopus 로고    scopus 로고
    • The biology of memory: A forty-year perspective
    • Kandel ER (2009) The biology of memory: a forty-year perspective. J Neurosci 29: 12748-12756.
    • (2009) J Neurosci , vol.29 , pp. 12748-12756
    • Kandel, E.R.1
  • 2
    • 77249127919 scopus 로고    scopus 로고
    • eIF2alpha Phosphorylation-dependent translation in CA1 pyramidal cells impairs hippo-campal memory consolidation without affecting general translation
    • Jiang Z, Belforte JE, Lu Y, Yabe Y, Pickel J, et al. (2010) eIF2alpha Phosphorylation-dependent translation in CA1 pyramidal cells impairs hippo-campal memory consolidation without affecting general translation. J Neurosci 30: 2582-2594.
    • (2010) J Neurosci , vol.30 , pp. 2582-2594
    • Jiang, Z.1    Belforte, J.E.2    Lu, Y.3    Yabe, Y.4    Pickel, J.5
  • 3
    • 0031055834 scopus 로고    scopus 로고
    • Molecular genetic analysis of synaptic plasticity, activity-dependent neural development, learning, and memory in the mammalian brain
    • Chen C, Tonegawa S (1997) Molecular genetic analysis of synaptic plasticity, activity-dependent neural development, learning, and memory in the mammalian brain. Annu Rev Neurosci 20: 157-184.
    • (1997) Annu Rev Neurosci , vol.20 , pp. 157-184
    • Chen, C.1    Tonegawa, S.2
  • 4
    • 0030446363 scopus 로고    scopus 로고
    • The essential role of hippocampal CA1 NMDA receptor-dependent synaptic plasticity in spatial memory
    • Tsien JZ, Huerta PT, Tonegawa S (1996) The essential role of hippocampal CA1 NMDA receptor-dependent synaptic plasticity in spatial memory. Cell 87: 1327-1338.
    • (1996) Cell , vol.87 , pp. 1327-1338
    • Tsien, J.Z.1    Huerta, P.T.2    Tonegawa, S.3
  • 5
    • 0037271080 scopus 로고    scopus 로고
    • Selective neuronal degeneration induced by soluble oligomeric amyloid beta protein
    • Kim HJ, Chae SC, Lee DK, Chromy B, Lee SC, et al. (2003) Selective neuronal degeneration induced by soluble oligomeric amyloid beta protein. FASEB J 17: 118-120.
    • (2003) FASEB J , vol.17 , pp. 118-120
    • Kim, H.J.1    Chae, S.C.2    Lee, D.K.3    Chromy, B.4    Lee, S.C.5
  • 6
    • 0032517186 scopus 로고    scopus 로고
    • Neuronal and volume loss in CA1 of the hippocampal formation uniquely predicts duration and severity of Alzheimer disease
    • Bobinski M, de Leon MJ, Tarnawski M, Wegiel J, Reisberg B, et al. (1998) Neuronal and volume loss in CA1 of the hippocampal formation uniquely predicts duration and severity of Alzheimer disease. Brain Res 805: 267-269.
    • (1998) Brain Res , vol.805 , pp. 267-269
    • Bobinski, M.1    de Leon, M.J.2    Tarnawski, M.3    Wegiel, J.4    Reisberg, B.5
  • 7
    • 0020051129 scopus 로고
    • Delayed neuronal death in the gerbil hippocampus following ischemia
    • Kirino T (1982) Delayed neuronal death in the gerbil hippocampus following ischemia. Brain Res 239: 57-69.
    • (1982) Brain Res , vol.239 , pp. 57-69
    • Kirino, T.1
  • 8
    • 0020067965 scopus 로고
    • Temporal profile of neuronal damage in a model of transient forebrain ischemia
    • Pulsinelli WA, Brierley JB, Plum F (1982) Temporal profile of neuronal damage in a model of transient forebrain ischemia. Ann Neurol 11: 491-498.
    • (1982) Ann Neurol , vol.11 , pp. 491-498
    • Pulsinelli, W.A.1    Brierley, J.B.2    Plum, F.3
  • 9
    • 0035251752 scopus 로고    scopus 로고
    • Nicotinic receptor-mediated protection against beta-amyloid neurotoxicity
    • Shimohama S, Kihara T (2001) Nicotinic receptor-mediated protection against beta-amyloid neurotoxicity. Biol Psychiatry 49: 233-239.
    • (2001) Biol Psychiatry , vol.49 , pp. 233-239
    • Shimohama, S.1    Kihara, T.2
  • 10
    • 34249075140 scopus 로고    scopus 로고
    • Alterations in intrinsic neuronal excitability during normal aging
    • Disterhoft JF, Oh MM (2007) Alterations in intrinsic neuronal excitability during normal aging. Aging Cell 6: 327-336.
    • (2007) Aging Cell , vol.6 , pp. 327-336
    • Disterhoft, J.F.1    Oh, M.M.2
  • 11
    • 66349124196 scopus 로고    scopus 로고
    • Memory deficits are associated with impaired ability to modulate neuronal excitability in middle-aged mice
    • Kaczorowski CC, Disterhoft JF (2009) Memory deficits are associated with impaired ability to modulate neuronal excitability in middle-aged mice. Learn Mem 16: 362-366.
    • (2009) Learn Mem , vol.16 , pp. 362-366
    • Kaczorowski, C.C.1    Disterhoft, J.F.2
  • 12
    • 58149237501 scopus 로고    scopus 로고
    • Expression of neuronal nicotinic acetylcholine receptor subunit mRNAs in rat hippocampal GABAergic interneurons
    • Son JH, Winzer-Serhan UH (2008) Expression of neuronal nicotinic acetylcholine receptor subunit mRNAs in rat hippocampal GABAergic interneurons. J Comp Neurol 511: 286-299.
    • (2008) J Comp Neurol , vol.511 , pp. 286-299
    • Son, J.H.1    Winzer-Serhan, U.H.2
  • 13
    • 58249113980 scopus 로고    scopus 로고
    • Mammalian nicotinic acetylcholine receptors: From structure to function
    • Albuquerque EX, Pereira EF, Alkondon M, Rogers SW (2009) Mammalian nicotinic acetylcholine receptors: from structure to function. Physiol Rev 89: 73-120.
    • (2009) Physiol Rev , vol.89 , pp. 73-120
    • Albuquerque, E.X.1    Pereira, E.F.2    Alkondon, M.3    Rogers, S.W.4
  • 14
    • 33947303210 scopus 로고    scopus 로고
    • Neuroprotection afforded by nicotine against oxygen and glucose deprivation in hippocampal slices is lost in alpha7 nicotinic receptor knockout mice
    • Egea J, Rosa AO, Sobrado M, Gandia L, Lopez MG, et al. (2007) Neuroprotection afforded by nicotine against oxygen and glucose deprivation in hippocampal slices is lost in alpha7 nicotinic receptor knockout mice. Neuroscience 145: 866-872.
    • (2007) Neuroscience , vol.145 , pp. 866-872
    • Egea, J.1    Rosa, A.O.2    Sobrado, M.3    Gandia, L.4    Lopez, M.G.5
  • 15
    • 50149114171 scopus 로고    scopus 로고
    • Dietary choline supplementation improves behavioral, histological, and neurochemical outcomes in a rat model of traumatic brain injury
    • Guseva MV, Hopkins DM, Scheff SW, Pauly JR (2008) Dietary choline supplementation improves behavioral, histological, and neurochemical outcomes in a rat model of traumatic brain injury. J Neurotrauma 25: 975-983.
    • (2008) J Neurotrauma , vol.25 , pp. 975-983
    • Guseva, M.V.1    Hopkins, D.M.2    Scheff, S.W.3    Pauly, J.R.4
  • 16
    • 0031975130 scopus 로고    scopus 로고
    • Nicotinic a7 receptors protect against glutamate neurotoxicity and neuronal ischemic damage
    • Shimohama S, Greenwald DL, Shafron DH, Akaike A, Maeda T, et al. (1998) Nicotinic a7 receptors protect against glutamate neurotoxicity and neuronal ischemic damage. Brain Res 779: 359-363.
    • (1998) Brain Res , vol.779 , pp. 359-363
    • Shimohama, S.1    Greenwald, D.L.2    Shafron, D.H.3    Akaike, A.4    Maeda, T.5
  • 17
    • 0344089297 scopus 로고    scopus 로고
    • Chronic nicotine treatment attenuates alpha 7 nicotinic receptor deficits following traumatic brain injury
    • Verbois SL, Scheff SW, Pauly JR (2003) Chronic nicotine treatment attenuates alpha 7 nicotinic receptor deficits following traumatic brain injury. Neurophar-macology 44: 224-233.
    • (2003) Neurophar-macology , vol.44 , pp. 224-233
    • Verbois, S.L.1    Scheff, S.W.2    Pauly, J.R.3
  • 18
    • 7244242447 scopus 로고    scopus 로고
    • Neuronal Nicotinic Receptor Subtypes: DEFINING THERAPEUTIC TARGETS
    • Buccafusco JJ, (2004) Neuronal Nicotinic Receptor Subtypes: DEFINING THERAPEUTIC TARGETS. MolInterv 4: 285-295.
    • (2004) MolInterv , vol.4 , pp. 285-295
    • Buccafusco, J.J.1
  • 19
    • 20544460348 scopus 로고    scopus 로고
    • Long-lasting cognitive improvement with nicotinic receptor agonists: Mechanisms of pharmacokinetic-pharmacodynamic discordance
    • Buccafusco JJ, Letchworth SR, Bencherif M, Lippiello PM (2005) Long-lasting cognitive improvement with nicotinic receptor agonists: mechanisms of pharmacokinetic-pharmacodynamic discordance. Trends Pharmacol Sci 26: 352-360.
    • (2005) Trends Pharmacol Sci , vol.26 , pp. 352-360
    • Buccafusco, J.J.1    Letchworth, S.R.2    Bencherif, M.3    Lippiello, P.M.4
  • 20
    • 75049085215 scopus 로고    scopus 로고
    • Mechanisms of neuroprotective effects of nicotine and acetylcholinesterase inhibitors: Role of alpha4 and alpha7 receptors in neuroprotection
    • Akaike A, Takada-Takatori Y, Kume T, Izumi Y (2010) Mechanisms of neuroprotective effects of nicotine and acetylcholinesterase inhibitors: role of alpha4 and alpha7 receptors in neuroprotection. J Mol Neurosci 40: 211-216.
    • (2010) J Mol Neurosci , vol.40 , pp. 211-216
    • Akaike, A.1    Takada-Takatori, Y.2    Kume, T.3    Izumi, Y.4
  • 21
    • 63149095488 scopus 로고    scopus 로고
    • Nicotinic receptor-mediated neuroprotection in neurode-generative disease models
    • Shimohama S, (2009) Nicotinic receptor-mediated neuroprotection in neurode-generative disease models. Biol Pharm Bull 32: 332-336.
    • (2009) Biol Pharm Bull , vol.32 , pp. 332-336
    • Shimohama, S.1
  • 22
    • 0033526629 scopus 로고    scopus 로고
    • Characterization of the neuroprotective and toxic effects of a7 nicotinic receptor activation in PC12 cells
    • Li Y, Papke RL, He YJ, Millard B, Meyer EM (1999) Characterization of the neuroprotective and toxic effects of a7 nicotinic receptor activation in PC12 cells. Brain Res 81: 218-225.
    • (1999) Brain Res , vol.81 , pp. 218-225
    • Li, Y.1    Papke, R.L.2    He, Y.J.3    Millard, B.4    Meyer, E.M.5
  • 23
    • 0033626286 scopus 로고    scopus 로고
    • The brain alpha7 nicotinic receptor may be an important therapeutic target for the treatment of Alzheimer's disease: Studies with DMXBA (GTS-21)
    • Kem WR, (2000) The brain alpha7 nicotinic receptor may be an important therapeutic target for the treatment of Alzheimer's disease: studies with DMXBA (GTS-21). Behav Brain Res 113: 169-181.
    • (2000) Behav Brain Res , vol.113 , pp. 169-181
    • Kem, W.R.1
  • 24
    • 0002100551 scopus 로고    scopus 로고
    • Effects of 3-[2,4-dimethoxybenzylidene]anabaseine (DMXB) on rat nicotinic receptors and memory-related behaviors
    • Meyer EM, Tay ET, Papke RL, Meyers C, Huang G, et al. (1997) Effects of 3-[2,4-dimethoxybenzylidene]anabaseine (DMXB) on rat nicotinic receptors and memory-related behaviors. Brain Res 768: 49-56.
    • (1997) Brain Res , vol.768 , pp. 49-56
    • Meyer, E.M.1    Tay, E.T.2    Papke, R.L.3    Meyers, C.4    Huang, G.5
  • 25
    • 34548683244 scopus 로고    scopus 로고
    • Profile of nicotinic acetylcholine receptor agonists ABT-594 and A-582941, with differential subtype selectivity, on delayed matching accuracy by young monkeys
    • Buccafusco JJ, Terry AV, Jr., Decker MW, Gopalakrishnan M, (2007) Profile of nicotinic acetylcholine receptor agonists ABT-594 and A-582941, with differential subtype selectivity, on delayed matching accuracy by young monkeys. Biochem Pharmacol 74: 1202-1211.
    • (2007) Biochem Pharmacol , vol.74 , pp. 1202-1211
    • Buccafusco, J.J.1    Terry Jr., A.V.2    Decker, M.W.3    Gopalakrishnan, M.4
  • 26
    • 0038690569 scopus 로고    scopus 로고
    • Safety, pharmacokinetics, and effects on cognitive function of multiple doses of GTS-21 in healthy, male volunteers
    • Kitagawa H, Takenouchi T, Azuma R, Wesnes KA, Kramer WG, et al. (2003) Safety, pharmacokinetics, and effects on cognitive function of multiple doses of GTS-21 in healthy, male volunteers. Neuropsychopharmacology 28: 542-551.
    • (2003) Neuropsychopharmacology , vol.28 , pp. 542-551
    • Kitagawa, H.1    Takenouchi, T.2    Azuma, R.3    Wesnes, K.A.4    Kramer, W.G.5
  • 27
    • 33846879380 scopus 로고    scopus 로고
    • alpha7 Nicotinic receptor gene delivery into mouse hippocampal neurons leads to functional receptor expression, improved spatial memory-related performance, and tau hyperphosphorylation
    • Ren K, Thinschmidt J, Liu J, Ai L, Papke RL, et al. (2007) alpha7 Nicotinic receptor gene delivery into mouse hippocampal neurons leads to functional receptor expression, improved spatial memory-related performance, and tau hyperphosphorylation. Neuroscience 145: 314-322.
    • (2007) Neuroscience , vol.145 , pp. 314-322
    • Ren, K.1    Thinschmidt, J.2    Liu, J.3    Ai, L.4    Papke, R.L.5
  • 28
    • 77949462775 scopus 로고    scopus 로고
    • Cognitive improvement by activation of alpha7 nicotinic acetylcholine receptors: From animal models to human pathophysiology
    • Thomsen MS, Hansen HH, Timmerman DB, Mikkelsen JD, (2010) Cognitive improvement by activation of alpha7 nicotinic acetylcholine receptors: from animal models to human pathophysiology. Curr Pharm Des 16: 323-343.
    • (2010) Curr Pharm Des , vol.16 , pp. 323-343
    • Thomsen, M.S.1    Hansen, H.H.2    Timmerman, D.B.3    Mikkelsen, J.D.4
  • 29
    • 67349209574 scopus 로고    scopus 로고
    • A cog in cognition: How the alpha 7 nicotinic acetylcholine receptor is geared towards improving cognitive deficits
    • Leiser SC, Bowlby MR, Comery TA, Dunlop J, (2009) A cog in cognition: how the alpha 7 nicotinic acetylcholine receptor is geared towards improving cognitive deficits. Pharmacol Ther 122: 302-311.
    • (2009) Pharmacol Ther , vol.122 , pp. 302-311
    • Leiser, S.C.1    Bowlby, M.R.2    Comery, T.A.3    Dunlop, J.4
  • 30
    • 34548684581 scopus 로고    scopus 로고
    • Treating schizophrenia symptoms with an alpha7 nicotinic agonist, from mice to men
    • Olincy A, Stevens KE, (2007) Treating schizophrenia symptoms with an alpha7 nicotinic agonist, from mice to men. Biochem Pharmacol 74: 1192-1201.
    • (2007) Biochem Pharmacol , vol.74 , pp. 1192-1201
    • Olincy, A.1    Stevens, K.E.2
  • 31
    • 77950444140 scopus 로고    scopus 로고
    • Research review: Cholinergic mechanisms, early brain development, and risk for schizophrenia
    • Ross RG, Stevens KE, Proctor WR, Leonard S, Kisley MA, et al. (2010) Research review: Cholinergic mechanisms, early brain development, and risk for schizophrenia. J Child Psychol Psychiatry 51: 535-549.
    • (2010) J Child Psychol Psychiatry , vol.51 , pp. 535-549
    • Ross, R.G.1    Stevens, K.E.2    Proctor, W.R.3    Leonard, S.4    Kisley, M.A.5
  • 32
    • 70349445275 scopus 로고    scopus 로고
    • Cellular distribution of the nicotinic acetylcholine receptor alpha7 subunit in rat hippocampus
    • Mielke JG, Mealing GA (2009) Cellular distribution of the nicotinic acetylcholine receptor alpha7 subunit in rat hippocampus. Neurosci Res 65: 296-306.
    • (2009) Neurosci Res , vol.65 , pp. 296-306
    • Mielke, J.G.1    Mealing, G.A.2
  • 33
    • 0030781278 scopus 로고    scopus 로고
    • Functional nicotinic ACh receptors on interneurones in the rat hippocampus
    • Jones S, Yakel JL, (1997) Functional nicotinic ACh receptors on interneurones in the rat hippocampus. J Physiol 504(Pt 3): 603-610.
    • (1997) J Physiol , vol.504 , Issue.PART 3 , pp. 603-610
    • Jones, S.1    Yakel, J.L.2
  • 34
    • 0033560926 scopus 로고    scopus 로고
    • Nicotinic receptor activation excites distinct subtypes of interneurons in the rat hippocampus
    • McQuiston AR, Madison DV, (1999) Nicotinic receptor activation excites distinct subtypes of interneurons in the rat hippocampus. J Neurosci 19: 2887-2896.
    • (1999) J Neurosci , vol.19 , pp. 2887-2896
    • McQuiston, A.R.1    Madison, D.V.2
  • 35
    • 0032520135 scopus 로고    scopus 로고
    • Acetylcholine activates an alpha-bungarotoxin-sensitive nicotinic current in rat hippocampal interneurons, but not pyramidal cells
    • Frazier CJ, Rollins YD, Breese CR, Leonard S, Freedman R, et al. (1998) Acetylcholine activates an alpha-bungarotoxin-sensitive nicotinic current in rat hippocampal interneurons, but not pyramidal cells. J Neurosci 18: 1187-1195.
    • (1998) J Neurosci , vol.18 , pp. 1187-1195
    • Frazier, C.J.1    Rollins, Y.D.2    Breese, C.R.3    Leonard, S.4    Freedman, R.5
  • 36
    • 0032531893 scopus 로고    scopus 로고
    • Synaptic potentials mediated via alpha-bungarotoxin-sensitive nicotinic acetylcholine receptors in rat hippocampal interneurons
    • Frazier CJ, Buhler AV, Weiner JL, Dunwiddie TV, (1998) Synaptic potentials mediated via alpha-bungarotoxin-sensitive nicotinic acetylcholine receptors in rat hippocampal interneurons. J Neurosci 18: 8228-8235.
    • (1998) J Neurosci , vol.18 , pp. 8228-8235
    • Frazier, C.J.1    Buhler, A.V.2    Weiner, J.L.3    Dunwiddie, T.V.4
  • 37
    • 75049083747 scopus 로고    scopus 로고
    • Functional distribution of nicotinic receptors in CA3 region of the hippocampus
    • Grybko M, Sharma G, Vijayaraghavan S, (2010) Functional distribution of nicotinic receptors in CA3 region of the hippocampus. J Mol Neurosci 40: 114-120.
    • (2010) J Mol Neurosci , vol.40 , pp. 114-120
    • Grybko, M.1    Sharma, G.2    Vijayaraghavan, S.3
  • 38
    • 0034879826 scopus 로고    scopus 로고
    • Timing and location of nicotinic activity enhances or depresses hippocampal synaptic plasticity
    • Ji D, Lape R, Dani JA (2001) Timing and location of nicotinic activity enhances or depresses hippocampal synaptic plasticity. Neuron 31: 131-141.
    • (2001) Neuron , vol.31 , pp. 131-141
    • Ji, D.1    Lape, R.2    Dani, J.A.3
  • 39
    • 34250739480 scopus 로고    scopus 로고
    • Advances in the discovery of novel positive allosteric modulators of the alpha7 nicotinic acetylcholine receptor
    • Faghih R, Gfesser GA, Gopalakrishnan M, (2007) Advances in the discovery of novel positive allosteric modulators of the alpha7 nicotinic acetylcholine receptor. Recent Patents CNS Drug Discov 2: 99-106.
    • (2007) Recent Patents CNS Drug Discov , vol.2 , pp. 99-106
    • Faghih, R.1    Gfesser, G.A.2    Gopalakrishnan, M.3
  • 40
    • 20944441082 scopus 로고    scopus 로고
    • A novel positive allosteric modulator of the alpha7 neuronal nicotinic acetylcholine receptor: In vitro and in vivo characterization
    • Hurst RS, Hajos M, Raggenbass M, Wall TM, Higdon NR, et al. (2005) A novel positive allosteric modulator of the alpha7 neuronal nicotinic acetylcholine receptor: in vitro and in vivo characterization. J Neurosci 25: 4396-4405.
    • (2005) J Neurosci , vol.25 , pp. 4396-4405
    • Hurst, R.S.1    Hajos, M.2    Raggenbass, M.3    Wall, T.M.4    Higdon, N.R.5
  • 41
    • 60149087435 scopus 로고    scopus 로고
    • Positive modulation of alpha7 nAChR responses in rat hippocampal interneurons to full agonists and the alpha7-selective partial agonists, 4OH-GTS-21 and S 24795
    • Lopez-Hernandez GY, Thinschmidt JS, Morain P, Trocme-Thibierge C, Kem WR, et al. (2009) Positive modulation of alpha7 nAChR responses in rat hippocampal interneurons to full agonists and the alpha7-selective partial agonists, 4OH-GTS-21 and S 24795. Neuropharmacology.
    • (2009) Neuropharmacology
    • Lopez-Hernandez, G.Y.1    Thinschmidt, J.S.2    Morain, P.3    Trocme-Thibierge, C.4    Kem, W.R.5
  • 42
    • 43449107357 scopus 로고    scopus 로고
    • Functional properties of alpha7 nicotinic acetylcholine receptors co-expressed with RIC-3 in a stable recombinant CHO-K1 cell line
    • Roncarati R, Seredenina T, Jow B, Jow F, Papini S, et al. (2008) Functional properties of alpha7 nicotinic acetylcholine receptors co-expressed with RIC-3 in a stable recombinant CHO-K1 cell line. Assay Drug Dev Technol 6: 181-193.
    • (2008) Assay Drug Dev Technol , vol.6 , pp. 181-193
    • Roncarati, R.1    Seredenina, T.2    Jow, B.3    Jow, F.4    Papini, S.5
  • 43
    • 78649749822 scopus 로고    scopus 로고
    • Physiological concentrations of choline activate native {alpha}7-containing nicotinic acetylcholine receptors in the presence of PNU-120596
    • Gusev AG, Uteshev VV, (2009) Physiological concentrations of choline activate native {alpha}7-containing nicotinic acetylcholine receptors in the presence of PNU-120596. J Pharmacol Exp Ther.
    • (2009) J Pharmacol Exp Ther
    • Gusev, A.G.1    Uteshev, V.V.2
  • 44
    • 55749111553 scopus 로고    scopus 로고
    • Potentiation of alpha7 nicotinic acetylcholine receptors via an allosteric transmembrane site
    • Young GT, Zwart R, Walker AS, Sher E, Millar NS, (2008) Potentiation of alpha7 nicotinic acetylcholine receptors via an allosteric transmembrane site. Proc Natl Acad Sci USA 105: 14686-14691.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 14686-14691
    • Young, G.T.1    Zwart, R.2    Walker, A.S.3    Sher, E.4    Millar, N.S.5
  • 45
    • 34548301101 scopus 로고    scopus 로고
    • Distinct profiles of alpha7 nAChR positive allosteric modulation revealed by structurally diverse chemotypes
    • Gronlien JH, Hakerud M, Ween H, Thorin-Hagene K, Briggs CA, et al. (2007) Distinct profiles of alpha7 nAChR positive allosteric modulation revealed by structurally diverse chemotypes. Mol Pharmacol 72: 715-724.
    • (2007) Mol Pharmacol , vol.72 , pp. 715-724
    • Gronlien, J.H.1    Hakerud, M.2    Ween, H.3    Thorin-Hagene, K.4    Briggs, C.A.5
  • 46
    • 0025949374 scopus 로고
    • Seizures increase acetylcholine and choline concentrations in rat brain regions
    • Jope RS, Gu X, (1991) Seizures increase acetylcholine and choline concentrations in rat brain regions. Neurochem Res 16: 1219-1226.
    • (1991) Neurochem Res , vol.16 , pp. 1219-1226
    • Jope, R.S.1    Gu, X.2
  • 47
    • 0025887884 scopus 로고
    • Time-dependent changes in cerebral choline and acetylcholine induced by transient global ischemia in rats
    • Scremin OU, Jenden DJ, (1991) Time-dependent changes in cerebral choline and acetylcholine induced by transient global ischemia in rats. Stroke 22: 643-647.
    • (1991) Stroke , vol.22 , pp. 643-647
    • Scremin, O.U.1    Jenden, D.J.2
  • 48
    • 0030051094 scopus 로고    scopus 로고
    • Cerebral ischemia in young and adult gerbils: Effects on cholinergic metabolism
    • Bertrand N, Ishii H, Spatz M, (1996) Cerebral ischemia in young and adult gerbils: effects on cholinergic metabolism. Neurochem Int 28: 293-297.
    • (1996) Neurochem Int , vol.28 , pp. 293-297
    • Bertrand, N.1    Ishii, H.2    Spatz, M.3
  • 49
    • 0032506752 scopus 로고    scopus 로고
    • Novel tools for production and purification of recombinant adenoassociated virus vectors
    • Grimm D, Kern A, Rittner K, Kleinschmidt JA, (1998) Novel tools for production and purification of recombinant adenoassociated virus vectors. Hum Gene Ther 9: 2745-2760.
    • (1998) Hum Gene Ther , vol.9 , pp. 2745-2760
    • Grimm, D.1    Kern, A.2    Rittner, K.3    Kleinschmidt, J.A.4
  • 50
    • 0032525089 scopus 로고    scopus 로고
    • Region-specific and calcium-dependent increase in dialysate choline levels by NMDA
    • Zapata A, Capdevila JL, Trullas R, (1998) Region-specific and calcium-dependent increase in dialysate choline levels by NMDA. J Neurosci 18: 3597-3605.
    • (1998) J Neurosci , vol.18 , pp. 3597-3605
    • Zapata, A.1    Capdevila, J.L.2    Trullas, R.3
  • 51
    • 0033777506 scopus 로고    scopus 로고
    • Lipid alterations in transient forebrain ischemia: Possible new mechanisms of CDP-choline neuroprotection
    • Rao AM, Hatcher JF, Dempsey RJ, (2000) Lipid alterations in transient forebrain ischemia: possible new mechanisms of CDP-choline neuroprotection. J Neurochem 75: 2528-2535.
    • (2000) J Neurochem , vol.75 , pp. 2528-2535
    • Rao, A.M.1    Hatcher, J.F.2    Dempsey, R.J.3
  • 52
    • 11144243802 scopus 로고    scopus 로고
    • Choline transporters, cholinergic transmission and cognition
    • Sarter M, Parikh V, (2005) Choline transporters, cholinergic transmission and cognition. Nat Rev Neurosci 6: 48-56.
    • (2005) Nat Rev Neurosci , vol.6 , pp. 48-56
    • Sarter, M.1    Parikh, V.2
  • 53
    • 33645278090 scopus 로고    scopus 로고
    • Cortical choline transporter function measured in vivo using choline-sensitive microelectrodes: Clearance of endogenous and exogenous choline and effects of removal of cholinergic terminals
    • Parikh V, Sarter M, (2006) Cortical choline transporter function measured in vivo using choline-sensitive microelectrodes: clearance of endogenous and exogenous choline and effects of removal of cholinergic terminals. J Neurochem 97: 488-503.
    • (2006) J Neurochem , vol.97 , pp. 488-503
    • Parikh, V.1    Sarter, M.2
  • 54
    • 0034602138 scopus 로고    scopus 로고
    • Choline and acetylcholine have similar kinetic properties of activation and desensitization on the alpha7 nicotinic receptors in rat hippocampal neurons
    • Mike A, Castro NG, Albuquerque EX, (2000) Choline and acetylcholine have similar kinetic properties of activation and desensitization on the alpha7 nicotinic receptors in rat hippocampal neurons. Brain Res 882: 155-168.
    • (2000) Brain Res , vol.882 , pp. 155-168
    • Mike, A.1    Castro, N.G.2    Albuquerque, E.X.3
  • 55
    • 78649733981 scopus 로고    scopus 로고
    • The allosteric modulator of {alpha}7 nicotinic receptors, PNU-120596, causes conformational changes in the extracellular ligand binding domain similar to acetylcholine
    • Barron SC, McLaughlin JT, See JA, Richards VL, Rosenberg RL, (2009) The allosteric modulator of {alpha}7 nicotinic receptors, PNU-120596, causes conformational changes in the extracellular ligand binding domain similar to acetylcholine. Mol Pharmacol.
    • (2009) Mol Pharmacol
    • Barron, S.C.1    McLaughlin, J.T.2    See, J.A.3    Richards, V.L.4    Rosenberg, R.L.5
  • 56
    • 0037387521 scopus 로고    scopus 로고
    • Regulation of neuronal function by choline and 4OH-GTS-21 through alpha 7 nicotinic receptors
    • Uteshev VV, Meyer EM, Papke RL, (2003) Regulation of neuronal function by choline and 4OH-GTS-21 through alpha 7 nicotinic receptors. Journal of Neurophysiology 89: 1797-1806.
    • (2003) Journal of Neurophysiology , vol.89 , pp. 1797-1806
    • Uteshev, V.V.1    Meyer, E.M.2    Papke, R.L.3
  • 57
    • 0032254325 scopus 로고    scopus 로고
    • Analysis of 40H-GTS-21 Selectivity and Activity at Human and Rat a7 Nicotinic Receptors
    • Meyer E, Kuryatov A, Gerzanich V, Lindstrom J, Papke RL, (1998) Analysis of 40H-GTS-21 Selectivity and Activity at Human and Rat a7 Nicotinic Receptors. J Pharmacol Exp Ther 287: 918-925.
    • (1998) J Pharmacol Exp Ther , vol.287 , pp. 918-925
    • Meyer, E.1    Kuryatov, A.2    Gerzanich, V.3    Lindstrom, J.4    Papke, R.L.5
  • 59
    • 0027984340 scopus 로고
    • Diversity of nicotinic acetylcholine receptors in rat hippocampal neurons. II. The rundown and inward rectification of agonist-elicited whole cell currents and identification of receptor subunits by in situ hybridization
    • Alkondon M, Reinhardt S, Lobron C, Hermsen B, Maelicke A, et al. (1994) Diversity of nicotinic acetylcholine receptors in rat hippocampal neurons. II. The rundown and inward rectification of agonist-elicited whole cell currents and identification of receptor subunits by in situ hybridization. J Phamacol Exp Ther 271: 494-506.
    • (1994) J Phamacol Exp Ther , vol.271 , pp. 494-506
    • Alkondon, M.1    Reinhardt, S.2    Lobron, C.3    Hermsen, B.4    Maelicke, A.5
  • 60
    • 0031410384 scopus 로고    scopus 로고
    • Choline is a selective agonist of alpha7 nicotinic acetylcholine receptors in the rat brain neurons
    • Alkondon M, Pereira EF, Cortes WS, Maelicke A, Albuquerque EX, (1997) Choline is a selective agonist of alpha7 nicotinic acetylcholine receptors in the rat brain neurons. Eur J Neurosci 9: 2734-2742.
    • (1997) Eur J Neurosci , vol.9 , pp. 2734-2742
    • Alkondon, M.1    Pereira, E.F.2    Cortes, W.S.3    Maelicke, A.4    Albuquerque, E.X.5
  • 61
    • 0036729768 scopus 로고    scopus 로고
    • Comparative pharmacology of rat and human alpha7 nAChR conducted with net charge analysis
    • Papke RL, Porter Papke JK, (2002) Comparative pharmacology of rat and human alpha7 nAChR conducted with net charge analysis. Br J Pharmacol 137: 49-61.
    • (2002) Br J Pharmacol , vol.137 , pp. 49-61
    • Papke, R.L.1    Papke, J.K.P.2
  • 62
    • 0030756236 scopus 로고    scopus 로고
    • Nicotinic receptor stimulation protects neurons against beta-amyloid toxicity
    • Kihara T, Shimohama S, Sawada H, Kimura J, Kume T, et al. (1997) Nicotinic receptor stimulation protects neurons against beta-amyloid toxicity. Ann Neurol 42: 159-163.
    • (1997) Ann Neurol , vol.42 , pp. 159-163
    • Kihara, T.1    Shimohama, S.2    Sawada, H.3    Kimura, J.4    Kume, T.5
  • 63
    • 0028278717 scopus 로고
    • Nicotine-induced protection of cultured cortical neurons against N-methyl-D-aspartate receptor-mediated glutamate cytotoxicity
    • Akaike A, Tamura Y, Yokota T, Shimohama S, Kimura J, (1994) Nicotine-induced protection of cultured cortical neurons against N-methyl-D-aspartate receptor-mediated glutamate cytotoxicity. Brain Res 644: 181-187.
    • (1994) Brain Res , vol.644 , pp. 181-187
    • Akaike, A.1    Tamura, Y.2    Yokota, T.3    Shimohama, S.4    Kimura, J.5
  • 64
    • 33748783328 scopus 로고    scopus 로고
    • Learning, aging and intrinsic neuronal plasticity
    • Disterhoft JF, Oh MM, (2006) Learning, aging and intrinsic neuronal plasticity. Trends Neurosci 29: 587-599.
    • (2006) Trends Neurosci , vol.29 , pp. 587-599
    • Disterhoft, J.F.1    Oh, M.M.2
  • 66
    • 0037032103 scopus 로고    scopus 로고
    • Activation and inhibition of native neuronal alpha-bungarotoxin-sensitive nicotinic ACh receptors
    • Uteshev VV, Meyer EM, Papke RL, (2002) Activation and inhibition of native neuronal alpha-bungarotoxin-sensitive nicotinic ACh receptors. Brain Research 948: 33-46.
    • (2002) Brain Research , vol.948 , pp. 33-46
    • Uteshev, V.V.1    Meyer, E.M.2    Papke, R.L.3
  • 67
    • 0028982464 scopus 로고
    • a-Bungarotoxin-sensitive hippocampal nicotinic receptor channel has a high calcium permeability
    • Castro NG, Albuquerque EX (1995) a-Bungarotoxin-sensitive hippocampal nicotinic receptor channel has a high calcium permeability. Biophys J 68: 516-524.
    • (1995) Biophys J , vol.68 , pp. 516-524
    • Castro, N.G.1    Albuquerque, E.X.2
  • 68
    • 73549108536 scopus 로고    scopus 로고
    • Evaluation of Ca2+ permeability of nicotinic acetylcholine receptors in hypothalamic histaminergic neurons
    • Uteshev VV, (2010) Evaluation of Ca2+ permeability of nicotinic acetylcholine receptors in hypothalamic histaminergic neurons. Acta Biochim Biophys Sin (Shanghai) 42: 8-20.
    • (2010) Acta Biochim Biophys Sin (Shanghai) , vol.42 , pp. 8-20
    • Uteshev, V.V.1
  • 69
    • 0034115333 scopus 로고    scopus 로고
    • Inhibition and disinhibition of pyramidal neurons by activation of nicotinic receptors on hippocampal interneurons
    • Ji D, Dani JA, (2000) Inhibition and disinhibition of pyramidal neurons by activation of nicotinic receptors on hippocampal interneurons. J Neurphysiol 83: 2682-2690.
    • (2000) J Neurphysiol , vol.83 , pp. 2682-2690
    • Ji, D.1    Dani, J.A.2
  • 70
    • 0005994352 scopus 로고    scopus 로고
    • Properties of neuronal nicotinic acetylcholine receptors: Pharmacological characterization and modulation of synaptic function
    • Albuquerque EX, Alkondon M, Pereira EF, Castro NG, Schrattenholz A, et al. (1997) Properties of neuronal nicotinic acetylcholine receptors: pharmacological characterization and modulation of synaptic function. J Pharmacol Exp Ther 280: 1117-1136.
    • (1997) J Pharmacol Exp Ther , vol.280 , pp. 1117-1136
    • Albuquerque, E.X.1    Alkondon, M.2    Pereira, E.F.3    Castro, N.G.4    Schrattenholz, A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.