Lipophilicity and its relationship with passive drug permeation

Pharmaceutical Research

Volumn 28, Issue 5, 2011, Pages 962-977

  Liu, Xiangli ^a   Testa, Bernard ^b   Fahr, Alfred ^a  

^a FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

^b LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

Author keywords

lipophilicity; permeation; quantitative structure permeation relationships

Indexed keywords

ACETYLSALICYLIC ACID; ALCOHOL DERIVATIVE; ALLOPURINOL; BARBITURIC ACID DERIVATIVE; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCIUM CHANNEL BLOCKING AGENT; CARBAMIC ACID DERIVATIVE; CHOLESTEROL; DICETYL PHOSPHATE; DIMYRISTOYLPHOSPHATIDYLCHOLINE; ENDOTHELIN RECEPTOR ANTAGONIST; FLUOROURACIL; FUSIDIC ACID; HISTAMINE H2 RECEPTOR ANTAGONIST; IMIDAZOLIDINE DERIVATIVE; LIPOSOME; NITROIMIDAZOLE; NONSTEROID ANTIINFLAMMATORY AGENT; PHOSPHOLIPID; STEROID;

ACTIVE TRANSPORT; ARTIFICIAL MEMBRANE; BLOOD BRAIN BARRIER; CELL MEMBRANE PERMEABILITY; CHROMATOGRAPHY; DRUG ABSORPTION; DRUG DIFFUSION; DRUG PENETRATION; DRUG TRANSPORT; HUMAN; INTESTINE EPITHELIUM; LIPOPHILICITY; MEMBRANE BIOLOGY; MEMBRANE STRUCTURE; MEMBRANE TRANSPORT; NONHUMAN; PASSIVE TRANSPORT; PERMEABILITY BARRIER; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; REVIEW; SKIN PERMEABILITY;

ANIMALS; BLOOD-BRAIN BARRIER; CELL MEMBRANE; HUMANS; INTESTINAL MUCOSA; MEMBRANE LIPIDS; PERMEABILITY; PHARMACOKINETICS; SKIN;

EID: 79955599163     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-010-0303-7     Document Type: Review

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