Drug design for ever, from hype to hope

Journal of Computer-Aided Molecular Design

Volumn 26, Issue 1, 2012, Pages 137-150

  Seddon, G ^a   Lounnas, V ^b   McGuire, R ^c   Van Den Bergh, T ^d   Bywater, R P ^e   Oliveira, L ^f   Vriend, G ^b  

^a Adelard Institute   (United Kingdom)

^b RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^c BioAxis Research   (Netherlands)

^d Bio Prodict   (Netherlands)

^e MAGDALEN COLLEGE   (United Kingdom)

^f FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Drug design; G protein coupled receptors; Protein modeling; QSAR; Review; Translational research

Indexed keywords

COMPUTATIONAL CHEMISTRY; GENETIC ALGORITHMS; INDUSTRIAL RESEARCH; PROTEINS;

DESIGN RESEARCH; DRUG DESIGN; G PROTEIN COUPLED RECEPTORS; HIGH THROUGHPUT SCREENING; HOMOLOGY MODELING; MOLECULAR ENTITIES; PROTEIN MODELS; QSAR; STRUCTURE-BASED; TRANSLATIONAL RESEARCH;

QUANTUM CHEMISTRY;

G PROTEIN COUPLED RECEPTOR;

BINDING AFFINITY; BINDING SITE; DRUG DESIGN; DRUG INDUSTRY; DRUG RESEARCH; LIGAND BINDING; MOLECULAR DOCKING; MOLECULAR DYNAMICS; MOLECULAR IMAGING; MOLECULAR MODEL; MOLECULAR RECOGNITION; PRIORITY JOURNAL; PROCESS DEVELOPMENT; PROCESS OPTIMIZATION; PROTEIN FUNCTION; QUANTITATIVE STRUCTURE ACTIVITY RELATION; REVIEW; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; THREE DIMENSIONAL IMAGING;

EID: 84857456514     PISSN: 0920654X     EISSN: 15734951     Source Type: Journal    
DOI: 10.1007/s10822-011-9519-9     Document Type: Review

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