SCOPUS 정보 검색 플랫폼

Journal of the American Chemical Society

Volumn 132, Issue 33, 2010, Pages 11443-11445

Conserved binding mode of human β2 adrenergic receptor inverse agonists and antagonist revealed by X-ray crystallography

(7) Wacker, Daniel a Fenalti, Gustavo a Brown, Monica A a Katritch, Vsevolod b Abagyan, Ruben b Cherezov, Vadim a Stevens, Raymond C a

a SCRIPPS RESEARCH INSTITUTE (United States)

b UNIVERSITY OF CALIFORNIA SAN DIEGO (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADRENERGIC RECEPTORS; ALPRENOLOL; AROMATIC MOIETIES; BINDING MODES; CONFORMATIONAL DIFFERENCES; CROSSDOCKING; DRUG DESIGN; G PROTEIN COUPLED RECEPTORS; GLOBAL IMPACTS; HYDROGEN BOND NETWORKS; IN-SILICO; LIGAND-BINDING SITES; LIGAND-RECEPTOR; LOCAL IMPACTS; PHARMACOLOGICAL PROPERTIES; RECEPTOR LIGANDS; STRUCTURAL REARRANGEMENT; X RAY CRYSTAL STRUCTURES;

ARGON; BINDING ENERGY; BINDING SITES; CHEMICAL COMPOUNDS; DOCKING; DRUG PRODUCTS; HYDROGEN; HYDROGEN BONDS; LIGANDS; X RAY CRYSTALLOGRAPHY;

CRYSTAL STRUCTURE;

3 ISOPROPYLAMINO 1 (7 METHYL 4 INDANYLOXY) 2 BUTANOL; ALPRENOLOL; BETA 2 ADRENERGIC RECEPTOR;

ARTICLE; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; DRUG BINDING SITE; DRUG DESIGN; DRUG RECEPTOR BINDING; HUMAN; HYDROGEN BOND; LIGAND BINDING; X RAY CRYSTALLOGRAPHY;

ADRENERGIC BETA-2 RECEPTOR AGONISTS; ADRENERGIC BETA-2 RECEPTOR ANTAGONISTS; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; HUMANS; LIGANDS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; RECEPTORS, ADRENERGIC, BETA-2;

EID: 77955779227 PISSN: 00027863 EISSN: 15205126 Source Type: Journal
DOI: 10.1021/ja105108q Document Type: Article

Times cited : (329)

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