A successful virtual screening application: Prediction of anticonvulsant activity in MES test of widely used pharmaceutical and food preservatives methylparaben and propylparaben

Journal of Computer-Aided Molecular Design

Volumn 21, Issue 9, 2007, Pages 527-538

  Talevi, Alan ^a,b   Bellera, Carolina L ^b   Castro, Eduardo A ^a   Bruno Blanch, Luis E ^b  

^a UNIVERSIDAD NACIONAL DE LA PLATA   (Argentina)

^b FACULTAD DE CIENCIAS EXACTAS   (Argentina)

Author keywords

Anticonvulsants; MES; Methylparaben; Propylparaben; Virtual Screening

Indexed keywords

SOFTWARE TESTING;

ANTICONVULSANT; ANTICONVULSANT ACTIVITY; CLINICAL USE; DISCRIMINANT FUNCTIONS; MAXIMAL ELECTROSHOCK; PROPYLPARABENS; SCREENING APPLICATION; TOPOLOGICAL DESCRIPTORS; TRAINING SETS; VIRTUAL SCREENING;

MAMMALS;

FOOD PRESERVATIVE; METHYL PARABEN; PHENYTOIN; PROPYL PARABEN; VALPROIC ACID;

ANIMAL EXPERIMENT; ANTICONVULSANT ACTIVITY; ARTICLE; DISCRIMINANT ANALYSIS; DRUG SCREENING; DRUG STRUCTURE; EXTERNAL VALIDITY; INTERNAL VALIDITY; MOUSE; NONHUMAN; PREDICTION; PRIORITY JOURNAL; SEIZURE; STRUCTURE ANALYSIS; VALIDATION STUDY; VIRTUAL REALITY;

EID: 35748950717     PISSN: 0920654X     EISSN: 15734951     Source Type: Journal    
DOI: 10.1007/s10822-007-9136-9     Document Type: Article

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