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Volumn 22, Issue 1, 2008, Pages 1-17
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Three-dimensional quantitative structure-activity relationship (3D QSAR) and pharmacophore elucidation of tetrahydropyran derivatives as serotonin and norepinephrine transporter inhibitors
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Author keywords
3DQSAR; CoMFA; NET; Pharmacophore; SERT
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Indexed keywords
ALIGNMENT;
ATOMS;
COMPUTATIONAL CHEMISTRY;
MOLECULAR GRAPHICS;
NOREPINEPHRINE;
PHARMACODYNAMICS;
3D-QSAR;
ANALYSIS MODELS;
COMPARATIVE MOLECULAR FIELD ANALYSIS;
INHIBITORY ACTIVITY;
NET;
PHARMACOPHORES;
PREDICTIVITY;
SEROTONIN;
TETRAHYDROPYRAN;
THREE DIMENSIONAL QUANTITATIVE STRUCTURE ACTIVITY RELATIONSHIP (3D QSAR);
MOLECULES;
2 BENZHYDRYL 5 [(3, 4 DICHLORO BENZYLAMINO)]TETRAHYDROPYRAN 4 OL;
2 BENZHYDRYL 5 [(4 TRIFLUOROMETHOXY BENZYLAMINO)]TETRAHYDROPYRAN 4 OL;
NORADRENALIN UPTAKE INHIBITOR;
SEROTONIN UPTAKE INHIBITOR;
TETRAHYDROPYRAN DERIVATIVE;
UNCLASSIFIED DRUG;
ANIMAL EXPERIMENT;
ARTICLE;
BINDING AFFINITY;
COMPARATIVE MOLECULAR FIELD ANALYSIS;
COMPUTER PREDICTION;
DRUG ACTIVITY;
DRUG CONFORMATION;
DRUG POTENCY;
DRUG SELECTIVITY;
DRUG SYNTHESIS;
NEUROTRANSMITTER UPTAKE;
NONHUMAN;
PHARMACOPHORE;
PRIORITY JOURNAL;
PROTEIN INTERACTION;
RAT;
STRUCTURE ACTIVITY RELATION;
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EID: 38649105515
PISSN: 0920654X
EISSN: 15734951
Source Type: Journal
DOI: 10.1007/s10822-007-9146-7 Document Type: Article |
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Times cited : (16)
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References (32)
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