-
1
-
-
39049144417
-
p53-dependent and p53-independent activation of autophagy by ARF
-
DOI 10.1158/0008-5472.CAN-07-2069
-
Abida WM, Gu W. (2008). p53-Dependent and p53-independent activation of autophagy by ARF. Cancer Res 68: 352-357. (Pubitemid 351380060)
-
(2008)
Cancer Research
, vol.68
, Issue.2
, pp. 352-357
-
-
Abida, W.M.1
Gu, W.2
-
2
-
-
37549063395
-
Expression of beclin-1, an autophagy-related protein, in gastric and colorectal cancers
-
Ahn CH, Jeong EG, Lee JW, Kim MS, Kim SH, Kim SS et al. (2007). Expression of beclin-1, an autophagy-related protein, in gastric and colorectal cancers. APMIS 115: 1344-1349.
-
(2007)
APMIS
, vol.115
, pp. 1344-1349
-
-
Ahn, C.H.1
Jeong, E.G.2
Lee, J.W.3
Kim, M.S.4
Kim, S.H.5
Kim, S.S.6
-
3
-
-
48249087666
-
Silencing of Bcl-2 expression by small interfering RNA induces autophagic cell death in MCF-7 breast cancer cells
-
Akar U, Chaves-Reyez A, Barria M, Tari A, Sanguino A, Kondo Y et al. (2008). Silencing of Bcl-2 expression by small interfering RNA induces autophagic cell death in MCF-7 breast cancer cells. Autophagy 4: 669-679.
-
(2008)
Autophagy
, vol.4
, pp. 669-679
-
-
Akar, U.1
Chaves-Reyez, A.2
Barria, M.3
Tari, A.4
Sanguino, A.5
Kondo, Y.6
-
4
-
-
77749233738
-
ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS
-
Alexander A, Cai SL, Kim J, Nanez A, Sahin M, MacLean KH et al. (2010). ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS. Proc Natl Acad Sci USA 107: 4153-4158.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 4153-4158
-
-
Alexander, A.1
Cai, S.L.2
Kim, J.3
Nanez, A.4
Sahin, M.5
MacLean, K.H.6
-
5
-
-
79955469013
-
Autophagy is essential to suppress cell stress and to allow BCR-Abl-mediated leukemogenesis
-
Altman BJ, Jacobs SR, Mason EF, Michalek RD, Macintyre AN, Coloff JL et al. (2011). Autophagy is essential to suppress cell stress and to allow BCR-Abl-mediated leukemogenesis. Oncogene 30: 1855-1867.
-
(2011)
Oncogene
, vol.30
, pp. 1855-1867
-
-
Altman, B.J.1
Jacobs, S.R.2
Mason, E.F.3
Michalek, R.D.4
MacIntyre, A.N.5
Coloff, J.L.6
-
6
-
-
64149090441
-
Autophagy provides nutrients but can lead to Chop-dependent induction of Bim to sensitize growth factor-deprived cells to apoptosis
-
Altman BJ, Wofford JA, Zhao Y, Coloff JL, Ferguson EC, Wieman HL et al. (2009). Autophagy provides nutrients but can lead to Chop-dependent induction of Bim to sensitize growth factor-deprived cells to apoptosis. Mol Biol Cell 20: 1180-1191.
-
(2009)
Mol Biol Cell
, vol.20
, pp. 1180-1191
-
-
Altman, B.J.1
Wofford, J.A.2
Zhao, Y.3
Coloff, J.L.4
Ferguson, E.C.5
Wieman, H.L.6
-
7
-
-
34347238938
-
Evidence that curcumin suppresses the growth of malignant gliomas in vitro and in vivo through induction of autophagy: Role of akt and extracellular signal-regulated kinase signaling pathways
-
DOI 10.1124/mol.106.033167
-
Aoki H, Takada Y, Kondo S, Sawaya R, Aggarwal BB, Kondo Y. (2007). Evidence that curcumin suppresses the growth of malignant gliomas in vitro and in vivo through induction of autophagy: role of Akt and extracellular signal-regulated kinase signaling pathways. Mol Pharmacol 72: 29-39. (Pubitemid 46998522)
-
(2007)
Molecular Pharmacology
, vol.72
, Issue.1
, pp. 29-39
-
-
Aoki, H.1
Takada, Y.2
Kondo, S.3
Sawaya, R.4
Aggarwal, B.B.5
Kondo, Y.6
-
8
-
-
0035929650
-
The tumor suppressor PTEN positively regulates macroautophagy by inhibiting the phosphatidylinositol 3-kinase/protein kinase B pathway
-
Arico S, Petiot A, Bauvy C, Dubbelhuis PF, Meijer AJ, Codogno P et al. (2001). The tumor suppressor PTEN positively regulates macroautophagy by inhibiting the phosphatidylinositol 3-kinase/protein kinase B pathway. J Biol Chem 276: 35243-35246.
-
(2001)
J Biol Chem
, vol.276
, pp. 35243-35246
-
-
Arico, S.1
Petiot, A.2
Bauvy, C.3
Dubbelhuis, P.F.4
Meijer, A.J.5
Codogno, P.6
-
9
-
-
77952559255
-
The Skp2 promoter integrates signaling through the NF-kappaB, p53, and Akt/GSK3beta pathways to regulate autophagy and apoptosis
-
Barre B, Perkins ND. (2010). The Skp2 promoter integrates signaling through the NF-kappaB, p53, and Akt/GSK3beta pathways to regulate autophagy and apoptosis. Mol Cell 38: 524-538.
-
(2010)
Mol Cell
, vol.38
, pp. 524-538
-
-
Barre, B.1
Perkins, N.D.2
-
10
-
-
77956668302
-
Cathepsin B facilitates autophagy-mediated apoptosis in SPARC overexpressed primitive neuroectodermal tumor cells
-
Bhoopathi P, Chetty C, Gujrati M, Dinh DH, Rao JS, Lakka S. (2010). Cathepsin B facilitates autophagy-mediated apoptosis in SPARC overexpressed primitive neuroectodermal tumor cells. Cell Death Differ 17: 1529-1539.
-
(2010)
Cell Death Differ
, vol.17
, pp. 1529-1539
-
-
Bhoopathi, P.1
Chetty, C.2
Gujrati, M.3
Dinh, D.H.4
Rao, J.S.5
Lakka, S.6
-
11
-
-
27944504351
-
p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death
-
DOI 10.1083/jcb.200507002
-
Bjorkoy G, Lamark T, Brech A, Outzen H, Perander M, Overvatn A et al. (2005). p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death. J Cell Biol 171: 603-614. (Pubitemid 41668720)
-
(2005)
Journal of Cell Biology
, vol.171
, Issue.4
, pp. 603-614
-
-
Bjorkoy, G.1
Lamark, T.2
Brech, A.3
Outzen, H.4
Perander, M.5
Overvatn, A.6
Stenmark, H.7
Johansen, T.8
-
12
-
-
0035936002
-
Transcription of the RelB gene is regulated by NF-κB
-
DOI 10.1038/sj/onc/1204868
-
Bren GD, Solan NJ, Miyoshi H, Pennington KN, Pobst LJ, Paya CV. (2001). Transcription of the RelB gene is regulated by NF-kappaB. Oncogene 20: 7722-7733. (Pubitemid 33121945)
-
(2001)
Oncogene
, vol.20
, Issue.53
, pp. 7722-7733
-
-
Bren, G.D.1
Solan, N.J.2
Miyoshi, H.3
Pennington, K.N.4
Pobst, L.J.5
Paya, C.V.6
-
13
-
-
33750565745
-
Inhibition of mammalian target of rapamycin or apoptotic pathway induces autophagy and radiosensitizes PTEN null prostate cancer cells
-
DOI 10.1158/0008-5472.CAN-06-0802
-
Cao C, Subhawong T, Albert JM, Kim KW, Geng L, Sekhar KR et al. (2006). Inhibition of mammalian target of rapamycin or apoptotic pathway induces autophagy and radiosensitizes PTEN null prostate cancer cells. Cancer Res 66: 10040-10047. (Pubitemid 44672057)
-
(2006)
Cancer Research
, vol.66
, Issue.20
, pp. 10040-10047
-
-
Cao, C.1
Subhawong, T.2
Albert, J.M.3
Kim, K.W.4
Geng, L.5
Sekhar, K.R.6
Gi, Y.J.7
Lu, B.8
-
14
-
-
51449094343
-
Akt induces apoptosis in neuroblastoma cells expressing a C98X vasopressin mutant following autophagy suppression
-
Castino R, Thepparit C, Bellio N, Murphy D, Isidoro C. (2008). Akt induces apoptosis in neuroblastoma cells expressing a C98X vasopressin mutant following autophagy suppression. J Neuroendocrinol 20: 1165-1175.
-
(2008)
J Neuroendocrinol
, vol.20
, pp. 1165-1175
-
-
Castino, R.1
Thepparit, C.2
Bellio, N.3
Murphy, D.4
Isidoro, C.5
-
15
-
-
33847754341
-
Concanavalin A induces autophagy in hepatoma cells and has a therapeutic effect in a murine in situ hepatoma model
-
Chang CP, Yang MC, Liu HS, Lin YS, Lei HY. (2007). Concanavalin A induces autophagy in hepatoma cells and has a therapeutic effect in a murine in situ hepatoma model. Hepatology 45: 286-296.
-
(2007)
Hepatology
, vol.45
, pp. 286-296
-
-
Chang, C.P.1
Yang, M.C.2
Liu, H.S.3
Lin, Y.S.4
Lei, H.Y.5
-
16
-
-
78650041248
-
Relative down-regulation of apoptosis and autophagy genes in colorectal cancer
-
Chang YT, Tseng HC, Huang CC, Chen YP, Chiang HC, Chou FP. (2011). Relative down-regulation of apoptosis and autophagy genes in colorectal cancer. Eur J Clin Invest 41: 84-92.
-
(2011)
Eur J Clin Invest
, vol.41
, pp. 84-92
-
-
Chang, Y.T.1
Tseng, H.C.2
Huang, C.C.3
Chen, Y.P.4
Chiang, H.C.5
Chou, F.P.6
-
17
-
-
37049027338
-
Nuclear factor-κB, an unappreciated tumor suppressor
-
DOI 10.1158/0008-5472.CAN-07-1576
-
Chen F, Castranova V. (2007). Nuclear factor-kappaB, an unappreciated tumor suppressor. Cancer Res 67: 11093-11098. (Pubitemid 350248529)
-
(2007)
Cancer Research
, vol.67
, Issue.23
, pp. 11093-11098
-
-
Chen, F.1
Castranova, V.2
-
18
-
-
47149092405
-
Targeting the p27 E3 ligase SCF(Skp2) results in p27-and Skp2-mediated cell-cycle arrest and activation of autophagy
-
Chen Q, Xie W, Kuhn DJ, Voorhees PM, Lopez-Girona A, Mendy D et al. (2008). Targeting the p27 E3 ligase SCF(Skp2) results in p27-and Skp2-mediated cell-cycle arrest and activation of autophagy. Blood 111: 4690-4699.
-
(2008)
Blood
, vol.111
, pp. 4690-4699
-
-
Chen, Q.1
Xie, W.2
Kuhn, D.J.3
Voorhees, P.M.4
Lopez-Girona, A.5
Mendy, D.6
-
19
-
-
0027269573
-
Human epithelial ovarian cancer allelotype
-
Cliby W, Ritland S, Hartmann L, Dodson M, Halling KC, Keeney G et al. (1993). Human epithelial ovarian cancer allelotype. Cancer Res 53: 2393-2398. (Pubitemid 23156830)
-
(1993)
Cancer Research
, vol.53
, Issue.10
, pp. 2393-2398
-
-
Cliby, W.1
Ritland, S.2
Hartmann, L.3
Dodson, M.4
Halling, K.C.5
Keeney, G.6
Podratz, K.C.7
Jenkins, R.B.8
-
20
-
-
66349100518
-
P65/RelA modulates BECN1 transcription and autophagy
-
Copetti T, Bertoli C, Dalla E, Demarchi F, Schneider C. (2009). p65/RelA modulates BECN1 transcription and autophagy. Mol Cell Biol 29: 2594-2608.
-
(2009)
Mol Cell Biol
, vol.29
, pp. 2594-2608
-
-
Copetti, T.1
Bertoli, C.2
Dalla, E.3
Demarchi, F.4
Schneider, C.5
-
21
-
-
33745885329
-
DRAM, a p53-Induced Modulator of Autophagy, Is Critical for Apoptosis
-
DOI 10.1016/j.cell.2006.05.034, PII S0092867406007598
-
Crighton D, Wilkinson S, O'Prey J, Syed N, Smith P, Harrison PR et al. (2006). DRAM, a p53-induced modulator of autophagy, is critical for apoptosis. Cell 126: 121-134. (Pubitemid 44040988)
-
(2006)
Cell
, vol.126
, Issue.1
, pp. 121-134
-
-
Crighton, D.1
Wilkinson, S.2
O'Prey, J.3
Syed, N.4
Smith, P.5
Harrison, P.R.6
Gasco, M.7
Garrone, O.8
Crook, T.9
Ryan, K.M.10
-
22
-
-
76349090912
-
The IKK complex contributes to the induction of autophagy
-
Criollo A, Senovilla L, Authier H, Maiuri MC, Morselli E, Vitale I et al. (2010). The IKK complex contributes to the induction of autophagy. EMBO J 29: 619-631.
-
(2010)
EMBO J
, vol.29
, pp. 619-631
-
-
Criollo, A.1
Senovilla, L.2
Authier, H.3
Maiuri, M.C.4
Morselli, E.5
Vitale, I.6
-
23
-
-
77957685199
-
Autophagy-independent LC3 function in vesicular traffic
-
de Haan CA, Molinari M, Reggiori F. (2010). Autophagy-independent LC3 function in vesicular traffic. Autophagy 6: 994-996.
-
(2010)
Autophagy
, vol.6
, pp. 994-996
-
-
De Haan, C.A.1
Molinari, M.2
Reggiori, F.3
-
24
-
-
33745713171
-
Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis
-
Degenhardt K, Mathew R, Beaudoin B, Bray K, Anderson D, Chen G et al. (2006). Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis. Cancer Cell 10: 51-64.
-
(2006)
Cancer Cell
, vol.10
, pp. 51-64
-
-
Degenhardt, K.1
Mathew, R.2
Beaudoin, B.3
Bray, K.4
Anderson, D.5
Chen, G.6
-
25
-
-
33947497050
-
Differential effects of endoplasmic reticulum stress-induced autophagy on cell survival
-
DOI 10.1074/jbc.M609267200
-
Ding WX, Ni HM, Gao W, Hou YF, Melan MA, Chen X et al. (2007). Differential effects of endoplasmic reticulum stress-induced autophagy on cell survival. J Biol Chem 282: 4702-4710. (Pubitemid 47101001)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.7
, pp. 4702-4710
-
-
Ding, W.-X.1
Ni, H.-M.2
Gao, W.3
Hou, Y.-F.4
Melan, M.A.5
Chen, X.6
Stolz, D.B.7
Shao, Z.-M.8
Yin, X.-M.9
-
26
-
-
78549252103
-
TGFbeta1 protects against mesangial cell apoptosis via induction of autophagy
-
Ding Y, Kim JK, Kim SI, Na HJ, Jun SY, Lee SJ et al. (2010). TGFbeta1 protects against mesangial cell apoptosis via induction of autophagy. J Biol Chem 285: 37909-37919.
-
(2010)
J Biol Chem
, vol.285
, pp. 37909-37919
-
-
Ding, Y.1
Kim, J.K.2
Kim, S.I.3
Na, H.J.4
Jun, S.Y.5
Lee, S.J.6
-
27
-
-
56449107131
-
Association of autophagy defect with a malignant phenotype and poor prognosis of hepatocellular carcinoma
-
Ding ZB, Shi YH, Zhou J, Qiu SJ, Xu Y, Dai Z et al. (2008). Association of autophagy defect with a malignant phenotype and poor prognosis of hepatocellular carcinoma. Cancer Res 68: 9167-9175.
-
(2008)
Cancer Res
, vol.68
, pp. 9167-9175
-
-
Ding, Z.B.1
Shi, Y.H.2
Zhou, J.3
Qiu, S.J.4
Xu, Y.5
Dai, Z.6
-
28
-
-
33750071414
-
NF-κB activation represses tumor necrosis factor-α-induced autophagy
-
DOI 10.1074/jbc.M602097200
-
Djavaheri-Mergny M, Amelotti M, Mathieu J, Besancon F, Bauvy C, Souquere S et al. (2006). NF-kappaB activation represses tumor necrosis factor-alpha-induced autophagy. J Biol Chem 281: 30373-30382. (Pubitemid 44582093)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.41
, pp. 30373-30382
-
-
Djavaheri-Mergny, M.1
Amelotti, M.2
Mathieu, J.3
Besancon, F.4
Bauvy, C.5
Souquere, S.6
Pierron, G.7
Codogno, P.8
-
29
-
-
79953203958
-
Inhibition of autophagosome formation by the benzoporphyrin derivative verteporfin
-
Donohue E, Tovey A, Vogl AW, Arns S, Sternberg E, Young RN et al. (2011). Inhibition of autophagosome formation by the benzoporphyrin derivative verteporfin. J Biol Chem 286: 7290-7300.
-
(2011)
J Biol Chem
, vol.286
, pp. 7290-7300
-
-
Donohue, E.1
Tovey, A.2
Vogl, A.W.3
Arns, S.4
Sternberg, E.5
Young, R.N.6
-
30
-
-
77951536199
-
ISG20L1 is a p53 family target gene that modulates genotoxic stress-induced autophagy
-
Eby KG, Rosenbluth JM, Mays DJ, Marshall CB, Barton CE, Sinha S et al. (2010). ISG20L1 is a p53 family target gene that modulates genotoxic stress-induced autophagy. Mol Cancer 9: 95.
-
(2010)
Mol Cancer
, vol.9
, pp. 95
-
-
Eby, K.G.1
Rosenbluth, J.M.2
Mays, D.J.3
Marshall, C.B.4
Barton, C.E.5
Sinha, S.6
-
31
-
-
0026667781
-
Early loss of heterozygosity on 17q in ovarian cancer
-
The Abe Ovarian Cancer Genetics Group
-
Eccles DM, Russell SE, Haites NE, Atkinson R, Bell DW, Gruber L et al. (1992). Early loss of heterozygosity on 17q in ovarian cancer. The Abe Ovarian Cancer Genetics Group. Oncogene 7: 2069-2072.
-
(1992)
Oncogene
, vol.7
, pp. 2069-2072
-
-
Eccles, D.M.1
Russell, S.E.2
Haites, N.E.3
Atkinson, R.4
Bell, D.W.5
Gruber, L.6
-
32
-
-
0141920730
-
Rab7 prevents growth factor-independent survival by inhibiting cell-autonomous nutrient transporter expression
-
Edinger AL, Cinalli RM, Thompson CB. (2003). Rab7 prevents growth factor-independent survival by inhibiting cell-autonomous nutrient transporter expression. Dev Cell 5: 571-582.
-
(2003)
Dev Cell
, vol.5
, pp. 571-582
-
-
Edinger, A.L.1
Cinalli, R.M.2
Thompson, C.B.3
-
33
-
-
79251587803
-
Phosphorylation of ULK1 (hATG1) by AMPactivated protein kinase connects energy sensing to mitophagy
-
Egan DF, Shackelford DB, Mihaylova MM, Gelino S, Kohnz RA, Mair W et al. (2011). Phosphorylation of ULK1 (hATG1) by AMPactivated protein kinase connects energy sensing to mitophagy. Science 331: 456-461.
-
(2011)
Science
, vol.331
, pp. 456-461
-
-
Egan, D.F.1
Shackelford, D.B.2
Mihaylova, M.M.3
Gelino, S.4
Kohnz, R.A.5
Mair, W.6
-
34
-
-
79953306808
-
Oncogenic ras-induced expression of noxa and beclin-1 promotes autophagic cell death and limits clonogenic survival
-
Elgendy M, Sheridan C, Brumatti G, Martin SJ. (2011). Oncogenic ras-induced expression of noxa and beclin-1 promotes autophagic cell death and limits clonogenic survival. Mol Cell 42: 23-35.
-
(2011)
Mol Cell
, vol.42
, pp. 23-35
-
-
Elgendy, M.1
Sheridan, C.2
Brumatti, G.3
Martin, S.J.4
-
35
-
-
78149475478
-
Akt and autophagy cooperate to promote survival of drug-resistant glioma
-
Fan QW, Cheng C, Hackett C, Feldman M, Houseman BT, Nicolaides T et al. (2010). Akt and autophagy cooperate to promote survival of drug-resistant glioma. Sci Signal 3: ra81.
-
(2010)
Sci Signal
, vol.3
-
-
Fan, Q.W.1
Cheng, C.2
Hackett, C.3
Feldman, M.4
Houseman, B.T.5
Nicolaides, T.6
-
36
-
-
77954310492
-
The regulation of energy metabolism and the IGF-1/mTOR pathways by the p53 protein
-
Feng Z, Levine AJ. (2010). The regulation of energy metabolism and the IGF-1/mTOR pathways by the p53 protein. Trends Cell Biol 20: 427-434.
-
(2010)
Trends Cell Biol
, vol.20
, pp. 427-434
-
-
Feng, Z.1
Levine, A.J.2
-
37
-
-
71549161146
-
Perifosine inhibits mammalian target of rapamycin signaling through facilitating degradation of major components in the mTOR axis and induces autophagy
-
Fu L, Kim YA, Wang X, Wu X, Yue P, Lonial S et al. (2009). Perifosine inhibits mammalian target of rapamycin signaling through facilitating degradation of major components in the mTOR axis and induces autophagy. Cancer Res 69: 8967-8976.
-
(2009)
Cancer Res
, vol.69
, pp. 8967-8976
-
-
Fu, L.1
Kim, Y.A.2
Wang, X.3
Wu, X.4
Yue, P.5
Lonial, S.6
-
38
-
-
50149095124
-
Autophagy is activated in pancreatic cancer cells and correlates with poor patient outcome
-
Fujii S, Mitsunaga S, YamazakiM, Hasebe T, Ishii G, KojimaMet al. (2008). Autophagy is activated in pancreatic cancer cells and correlates with poor patient outcome. Cancer Sci 99: 1813-1819.
-
(2008)
Cancer Sci
, vol.99
, pp. 1813-1819
-
-
Fujii, S.1
Mitsunaga, S.2
Yamazaki, M.3
Hasebe, T.4
Ishii, G.5
Kojima, M.6
-
39
-
-
38049148611
-
Pivotal role of the cyclin-dependent kinase inhibitor p21WAF1/CIP1 in apoptosis and autophagy
-
Fujiwara K, Daido S, Yamamoto A, Kobayashi R, Yokoyama T, Aoki H et al. (2008). Pivotal role of the cyclin-dependent kinase inhibitor p21WAF1/CIP1 in apoptosis and autophagy. J Biol Chem 283: 388-397.
-
(2008)
J Biol Chem
, vol.283
, pp. 388-397
-
-
Fujiwara, K.1
Daido, S.2
Yamamoto, A.3
Kobayashi, R.4
Yokoyama, T.5
Aoki, H.6
-
40
-
-
41449109334
-
Induction of autophagy during extracellular matrix detachment promotes cell survival
-
DOI 10.1091/mbc.E07-10-1092
-
Fung C, Lock R, Gao S, Salas E, Debnath J. (2008). Induction of autophagy during extracellular matrix detachment promotes cell survival. Mol Biol Cell 19: 797-806. (Pubitemid 351481798)
-
(2008)
Molecular Biology of the Cell
, vol.19
, Issue.3
, pp. 797-806
-
-
Fung, C.1
Lock, R.2
Gao, S.3
Salas, E.4
Debnath, J.5
-
41
-
-
0026709013
-
Detection of frequent allelic loss on proximal chromosome 17q in sporadic breast carcinoma using microsatellite length polymorphisms
-
Futreal PA, Soderkvist P, Marks JR, Iglehart JD, Cochran C, Barrett JC et al. (1992). Detection of frequent allelic loss on proximal chromosome 17q in sporadic breast carcinoma using microsatellite length polymorphisms. Cancer Res 52: 2624-2627.
-
(1992)
Cancer Res
, vol.52
, pp. 2624-2627
-
-
Futreal, P.A.1
Soderkvist, P.2
Marks, J.R.3
Iglehart, J.D.4
Cochran, C.5
Barrett, J.C.6
-
42
-
-
31144471231
-
Apoptosis and autophagy induced by TGF-B1 in bovine mammary epithelial BME-UV1 cells
-
Gajewska M, Gajkowska B, Motyl T. (2005). Apoptosis and autophagy induced by TGF-B1 in bovine mammary epithelial BME-UV1 cells. J Physiol Pharmacol 56(Suppl 3): 143-157. (Pubitemid 43129239)
-
(2005)
Journal of Physiology and Pharmacology
, vol.56
, Issue.SUPPL. 3
, pp. 143-157
-
-
Gajewska, M.1
Gajkowska, B.2
Motyl, T.3
-
43
-
-
66449083078
-
ULK1.ATG13.FIP200 complex mediates mTOR signaling and is essential for autophagy
-
Ganley IG, Lam du H, Wang J, Ding X, Chen S, Jiang X. (2009). ULK1.ATG13.FIP200 complex mediates mTOR signaling and is essential for autophagy. J Biol Chem 284: 12297-12305.
-
(2009)
J Biol Chem
, vol.284
, pp. 12297-12305
-
-
Ganley, I.G.1
Lam Du, H.2
Wang, J.3
Ding, X.4
Chen, S.5
Jiang, X.6
-
44
-
-
77955485416
-
The Bcl-2 homology domain 3 mimetic gossypol induces both Beclin 1-dependent and Beclin 1-independent cytoprotective autophagy in cancer cells
-
Gao P, Bauvy C, Souquere S, Tonelli G, Liu L, Zhu Y et al. (2010). The Bcl-2 homology domain 3 mimetic gossypol induces both Beclin 1-dependent and Beclin 1-independent cytoprotective autophagy in cancer cells. J Biol Chem 285: 25570-25781.
-
(2010)
J Biol Chem
, vol.285
, pp. 25570-25781
-
-
Gao, P.1
Bauvy, C.2
Souquere, S.3
Tonelli, G.4
Liu, L.5
Zhu, Y.6
-
45
-
-
80052719816
-
Upregulation of human autophagy-initiation kinase ULK1 by tumor suppressor p53 contributes to DNA-damage-induced cell death
-
doi:10.1038/cdd.2011.33)
-
Gao W, Shen Z, Shang L, Wang X. (2011). Upregulation of human autophagy-initiation kinase ULK1 by tumor suppressor p53 contributes to DNA-damage-induced cell death. Cell Death Differ (doi:10.1038/cdd.2011.33).
-
(2011)
Cell Death Differ
-
-
Gao, W.1
Shen, Z.2
Shang, L.3
Wang, X.4
-
46
-
-
0028911287
-
Loss of heterozygosity of the BRCA1 and other loci on chromosome 17q in human prostate cancer
-
Gao X, Zacharek A, Salkowski A, Grignon DJ, Sakr W, Porter AT et al. (1995). Loss of heterozygosity of the BRCA1 and other loci on chromosome 17q in human prostate cancer. Cancer Res 55: 1002-1005.
-
(1995)
Cancer Res
, vol.55
, pp. 1002-1005
-
-
Gao, X.1
Zacharek, A.2
Salkowski, A.3
Grignon, D.J.4
Sakr, W.5
Porter, A.T.6
-
47
-
-
44149121946
-
1 semi-selectively kills cancer cells by a distinct mechanism, which involves the lysosomal-mitochondrial death pathway
-
DOI 10.1111/j.1582-4934.2008.00129.x
-
Ghavami S, Asoodeh A, Klonisch T, Halayko AJ, Kadkhoda K, Kroczak TJ et al. (2008). Brevinin-2R(1) semi-selectively kills cancer cells by a distinct mechanism, which involves the lysosomalmitochondrial death pathway. J Cell Mol Med 12: 1005-1022. (Pubitemid 351718078)
-
(2008)
Journal of Cellular and Molecular Medicine
, vol.12
, Issue.3
, pp. 1005-1022
-
-
Ghavami, S.1
Asoodeh, A.2
Klonisch, T.3
Halayko, A.J.4
Kadkhoda, K.5
Kroczak, T.J.6
Gibson, S.B.7
Booy, E.P.8
Naderi-Manesh, H.9
Los, M.10
-
48
-
-
8844239959
-
Effect of IGF-1 on the balance between autophagy of dysfunctional mitochondria and apoptosis
-
DOI 10.1016/j.febslet.2004.10.040, PII S0014579304012645
-
Gu Y, Wang C, Cohen A. (2004). Effect of IGF-1 on the balance between autophagy of dysfunctional mitochondria and apoptosis. FEBS Lett 577: 357-360. (Pubitemid 39535313)
-
(2004)
FEBS Letters
, vol.577
, Issue.3
, pp. 357-360
-
-
Gu, Y.1
Wang, C.2
Cohen, A.3
-
49
-
-
79952228407
-
Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis
-
Guo JY, Chen HY, Mathew R, Fan J, Strohecker AM, Karsli-Uzunbas G et al. (2011). Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis. Genes Dev 25: 460-470.
-
(2011)
Genes Dev
, vol.25
, pp. 460-470
-
-
Guo, J.Y.1
Chen, H.Y.2
Mathew, R.3
Fan, J.4
Strohecker, A.M.5
Karsli-Uzunbas, G.6
-
50
-
-
77956282607
-
Autophagy inhibition and antimalarials promote cell death in gastrointestinal stromal tumor (GIST
-
Gupta A, Roy S, Lazar AJ, Wang WL, McAuliffe JC, Reynoso D et al. (2010). Autophagy inhibition and antimalarials promote cell death in gastrointestinal stromal tumor (GIST). Proc Natl Acad Sci USA 107: 14333-14338.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 14333-14338
-
-
Gupta, A.1
Roy, S.2
Lazar, A.J.3
Wang, W.L.4
McAuliffe, J.C.5
Reynoso, D.6
-
51
-
-
3242877218
-
Rab7 is required for the normal progression of the autophagic pathway in mammalian cells
-
DOI 10.1242/jcs.01114
-
Gutierrez MG, Munafo DB, Beron W, Colombo MI. (2004). Rab7 is required for the normal progression of the autophagic pathway in mammalian cells. J Cell Sci 117: 2687-2697. (Pubitemid 38997252)
-
(2004)
Journal of Cell Science
, vol.117
, Issue.13
, pp. 2687-2697
-
-
Gutierrez, M.G.1
Munafo, D.B.2
Beron, W.3
Colombo, M.I.4
-
52
-
-
50349098812
-
Involvement of protective autophagy in TRAIL resistance of apoptosis-defective tumor cells
-
Han J, Hou W, Goldstein LA, Lu C, Stolz DB, Yin XM et al. (2008). Involvement of protective autophagy in TRAIL resistance of apoptosis-defective tumor cells. J Biol Chem 283: 19665-19677.
-
(2008)
J Biol Chem
, vol.283
, pp. 19665-19677
-
-
Han, J.1
Hou, W.2
Goldstein, L.A.3
Lu, C.4
Stolz, D.B.5
Yin, X.M.6
-
53
-
-
34250748014
-
Shikonin circumvents cancer drug resistance by induction of a necroptotic death
-
DOI 10.1158/1535-7163.MCT-06-0511
-
Han W, Li L, Qiu S, Lu Q, Pan Q, Gu Y et al. (2007). Shikonin circumvents cancer drug resistance by induction of a necroptotic death. Mol Cancer Ther 6: 1641-1649. (Pubitemid 46954031)
-
(2007)
Molecular Cancer Therapeutics
, vol.6
, Issue.5
, pp. 1641-1649
-
-
Han, W.1
Li, L.2
Qiu, S.3
Lu, Q.4
Pan, Q.5
Gu, Y.6
Luo, J.7
Hu, X.8
-
54
-
-
62649146372
-
TAK1 activates AMPKdependent cytoprotective autophagy in TRAIL-treated epithelial cells
-
Herrero-Martin G, Hoyer-Hansen M, Garcia-Garcia C, Fumarola C, Farkas T, Lopez-Rivas A et al. (2009). TAK1 activates AMPKdependent cytoprotective autophagy in TRAIL-treated epithelial cells. EMBO J 28: 677-685.
-
(2009)
EMBO J
, vol.28
, pp. 677-685
-
-
Herrero-Martin, G.1
Hoyer-Hansen, M.2
Garcia-Garcia, C.3
Fumarola, C.4
Farkas, T.5
Lopez-Rivas, A.6
-
55
-
-
34250891313
-
AMP-activated protein kinase: A universal regulator of autophagy?
-
Hoyer-Hansen M, Jaattela M. (2007). AMP-activated protein kinase: a universal regulator of autophagy? Autophagy 3: 381-383. (Pubitemid 46986350)
-
(2007)
Autophagy
, vol.3
, Issue.4
, pp. 381-383
-
-
Hoyer-Hansen, M.1
Jaattela, M.2
-
56
-
-
66349103732
-
Cathepsin L mediates resveratrol-induced autophagy and apoptotic cell death in cervical cancer cells
-
Hsu KF, Wu CL, Huang SC, Wu CM, Hsiao JR, Yo YT et al. (2009). Cathepsin L mediates resveratrol-induced autophagy and apoptotic cell death in cervical cancer cells. Autophagy 5: 451-460.
-
(2009)
Autophagy
, vol.5
, pp. 451-460
-
-
Hsu, K.F.1
Wu, C.L.2
Huang, S.C.3
Wu, C.M.4
Hsiao, J.R.5
Yo, Y.T.6
-
57
-
-
77953530983
-
Celecoxib-induced apoptosis is enhanced by ABT-737 and by inhibition of autophagy in human colorectal cancer cells
-
Huang S, Sinicrope FA. (2010). Celecoxib-induced apoptosis is enhanced by ABT-737 and by inhibition of autophagy in human colorectal cancer cells. Autophagy 6: 256-269.
-
(2010)
Autophagy
, vol.6
, pp. 256-269
-
-
Huang, S.1
Sinicrope, F.A.2
-
58
-
-
78049460392
-
Reduced expression of LC3B-II and Beclin 1 in glioblastoma multiforme indicates a down-regulated autophagic capacity that relates to the progression of astrocytic tumors
-
Huang X, Bai HM, Chen L, Li B, Lu YC. (2010). Reduced expression of LC3B-II and Beclin 1 in glioblastoma multiforme indicates a down-regulated autophagic capacity that relates to the progression of astrocytic tumors. J Clin Neurosci 17: 1515-1519.
-
(2010)
J Clin Neurosci
, vol.17
, pp. 1515-1519
-
-
Huang, X.1
Bai, H.M.2
Chen, L.3
Li, B.4
Lu, Y.C.5
-
59
-
-
77956392170
-
NF-kappaB as a common signaling pathway in ganglioside-induced autophagic cell death and activation of astrocytes
-
Hwang J, Lee HJ, Lee WH, Suk K. (2010). NF-kappaB as a common signaling pathway in ganglioside-induced autophagic cell death and activation of astrocytes. J Neuroimmunol 226: 66-72.
-
(2010)
J Neuroimmunol
, vol.226
, pp. 66-72
-
-
Hwang, J.1
Lee, H.J.2
Lee, W.H.3
Suk, K.4
-
60
-
-
77950800322
-
Role of hypoxia and autophagy in MDA-MB-231 invasiveness
-
Indelicato M, Pucci B, Schito L, Reali V, Aventaggiato M, Mazzarino MC et al. (2010). Role of hypoxia and autophagy in MDA-MB-231 invasiveness. J Cell Physiol 223: 359-368.
-
(2010)
J Cell Physiol
, vol.223
, pp. 359-368
-
-
Indelicato, M.1
Pucci, B.2
Schito, L.3
Reali, V.4
Aventaggiato, M.5
Mazzarino, M.C.6
-
61
-
-
33947495259
-
Silencing mammalian target of rapamycin signaling by small interfering RNA enhances rapamycin-induced autophagy in malignant glioma cells
-
DOI 10.1038/sj.onc.1209992, PII 1209992
-
Iwamaru A, Kondo Y, Iwado E, Aoki H, Fujiwara K, Yokoyama T et al. (2007). Silencing mammalian target of rapamycin signaling by small interfering RNA enhances rapamycin-induced autophagy in malignant glioma cells. Oncogene 26: 1840-1851. (Pubitemid 46474638)
-
(2007)
Oncogene
, vol.26
, Issue.13
, pp. 1840-1851
-
-
Iwamaru, A.1
Kondo, Y.2
Iwado, E.3
Aoki, H.4
Fujiwara, K.5
Yokoyama, T.6
Mills, G.B.7
Kondo, S.8
-
62
-
-
7244255989
-
Role for Rab7 in maturation of late autophagic vacuoles
-
DOI 10.1242/jcs.01370
-
Jager S, Bucci C, Tanida I, Ueno T, Kominami E, Saftig P et al. (2004). Role for Rab7 in maturation of late autophagic vacuoles. J Cell Sci 117: 4837-4848. (Pubitemid 39433449)
-
(2004)
Journal of Cell Science
, vol.117
, Issue.20
, pp. 4837-4848
-
-
Jager, S.1
Bucci, C.2
Tanida, I.3
Ueno, T.4
Kominami, E.5
Saftig, P.6
Eskelinen, E.-L.7
-
63
-
-
78649284539
-
RB-E2F1: Molecular rheostat for autophagy and apoptosis
-
Jiang H, Martin V, Alonso M, Gomez-Manzano C, Fueyo J. (2010b). RB-E2F1: molecular rheostat for autophagy and apoptosis. Autophagy 6: 1216-1217.
-
(2010)
Autophagy
, vol.6
, pp. 1216-1217
-
-
Jiang, H.1
Martin, V.2
Alonso, M.3
Gomez-Manzano, C.4
Fueyo, J.5
-
64
-
-
78049262912
-
The RB-E2F1 pathway regulates autophagy
-
Jiang H, Martin V, Gomez-Manzano C, Johnson DG, Alonso M, White E et al. (2010a). The RB-E2F1 pathway regulates autophagy. Cancer Res 70: 7882-7893.
-
(2010)
Cancer Res
, vol.70
, pp. 7882-7893
-
-
Jiang, H.1
Martin, V.2
Gomez-Manzano, C.3
Johnson, D.G.4
Alonso, M.5
White, E.6
-
65
-
-
65249176304
-
ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery
-
Jung CH, Jun CB, Ro SH, Kim YM, Otto NM, Cao J et al. (2009). ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery. Mol Biol Cell 20: 1992-2003.
-
(2009)
Mol Biol Cell
, vol.20
, pp. 1992-2003
-
-
Jung, C.H.1
Jun, C.B.2
Ro, S.H.3
Kim, Y.M.4
Otto, N.M.5
Cao, J.6
-
66
-
-
54049135563
-
The Bcr-Abl kinase inhibitor INNO-406 induces autophagy and different modes of cell death execution in Bcr-Abl-positive leukemias
-
Kamitsuji Y, Kuroda J, Kimura S, Toyokuni S, Watanabe K, Ashihara E et al. (2008). The Bcr-Abl kinase inhibitor INNO-406 induces autophagy and different modes of cell death execution in Bcr-Abl-positive leukemias. Cell Death Differ 15: 1712-1722.
-
(2008)
Cell Death Differ
, vol.15
, pp. 1712-1722
-
-
Kamitsuji, Y.1
Kuroda, J.2
Kimura, S.3
Toyokuni, S.4
Watanabe, K.5
Ashihara, E.6
-
67
-
-
74949132928
-
The EphB2 tumor suppressor induces autophagic cell death via concomitant activation of the ERK1/2 and PI3K pathways
-
Kandouz M, Haidara K, Zhao J, Brisson ML, Batist G. (2010). The EphB2 tumor suppressor induces autophagic cell death via concomitant activation of the ERK1/2 and PI3K pathways. Cell Cycle 9: 398-407.
-
(2010)
Cell Cycle
, vol.9
, pp. 398-407
-
-
Kandouz, M.1
Haidara, K.2
Zhao, J.3
Brisson, M.L.4
Batist, G.5
-
68
-
-
34548421950
-
Dual roles of autophagy in the survival of Caenorhabditis elegans during starvation
-
DOI 10.1101/gad.1573107
-
Kang C, You YJ, Avery L. (2007). Dual roles of autophagy in the survival of Caenorhabditis elegans during starvation. Genes Dev 21: 2161-2171. (Pubitemid 47360838)
-
(2007)
Genes and Development
, vol.21
, Issue.17
, pp. 2161-2171
-
-
Kang, C.1
You, N.-J.2
Avery, L.3
-
69
-
-
64549101639
-
Frameshift mutations of autophagy-related genes ATG2B, ATG5, ATG9B and ATG12 in gastric and colorectal cancers with microsatellite instability
-
Kang MR, Kim MS, Oh JE, Kim YR, Song SY, Kim SS et al. (2009). Frameshift mutations of autophagy-related genes ATG2B, ATG5, ATG9B and ATG12 in gastric and colorectal cancers with microsatellite instability. J Pathol 217: 702-706.
-
(2009)
J Pathol
, vol.217
, pp. 702-706
-
-
Kang, M.R.1
Kim, M.S.2
Oh, J.E.3
Kim, Y.R.4
Song, S.Y.5
Kim, S.S.6
-
70
-
-
79955596127
-
LC3A autophagic activity and prognostic significance in non-small cell lung carcinomas
-
doi:10.1378/chest.10-1831)
-
Karpathiou G, Sivridis E, Koukourakis M, Mikroulis D, Bouros D, Froudarakis M et al. (2010). LC3A autophagic activity and prognostic significance in non-small cell lung carcinomas. Chest (doi:10.1378/chest.10- 1831).
-
(2010)
Chest
-
-
Karpathiou, G.1
Sivridis, E.2
Koukourakis, M.3
Mikroulis, D.4
Bouros, D.5
Froudarakis, M.6
-
71
-
-
0031448836
-
NotI linking/jumping clones of human chromosome 3: Mapping of the TFRC, RAB7 and HAUSP genes to regions rearranged in leukemia and deleted in solid tumors
-
DOI 10.1016/S0014-5793(97)01449-X, PII S001457939701449X
-
Kashuba VI, Gizatullin RZ, Protopopov AI, Allikmets R, Korolev S, Li J et al. (1997). NotI linking/jumping clones of human chromosome 3: mapping of the TFRC, RAB7 and HAUSP genes to regions rearranged in leukemia and deleted in solid tumors. FEBS Lett 419: 181-185. (Pubitemid 28010806)
-
(1997)
FEBS Letters
, vol.419
, Issue.2-3
, pp. 181-185
-
-
Kashuba, V.I.1
Gizatullin, R.Z.2
Protopopov, A.I.3
Allikmets, R.4
Korolev, S.5
Li, J.6
Boldog, F.7
Tory, K.8
Zabarovska, V.9
Marcsek, Z.10
Sumegi, J.11
Klein, G.12
Zabarovsky, E.R.13
Kisselev, L.14
-
72
-
-
34447132925
-
Sodium selenite induces superoxide-mediated mitochondrial damage and subsequent autophagic cell death in malignant glioma cells
-
DOI 10.1158/0008-5472.CAN-06-4217
-
Kim EH, Sohn S, Kwon HJ, Kim SU, Kim MJ, Lee SJ et al. (2007). Sodium selenite induces superoxide-mediated mitochondrial damage and subsequent autophagic cell death in malignant glioma cells. Cancer Res 67: 6314-6324. (Pubitemid 47037514)
-
(2007)
Cancer Research
, vol.67
, Issue.13
, pp. 6314-6324
-
-
Eun, H.K.1
Sohn, S.2
Hyuk, J.K.3
Kim, S.U.4
Kim, M.-J.5
Lee, S.-J.6
Kyeong, S.C.7
-
73
-
-
79551598347
-
AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1
-
Kim J, Kundu M, Viollet B, Guan KL. (2011). AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1. Nat Cell Biol 13: 132-141.
-
(2011)
Nat Cell Biol
, vol.13
, pp. 132-141
-
-
Kim, J.1
Kundu, M.2
Viollet, B.3
Guan, K.L.4
-
74
-
-
48249090416
-
Autophagy upregulation by inhibitors of caspase-3 and mTOR enhances radiotherapy in a mouse model of lung cancer
-
Kim KW, Hwang M, Moretti L, Jaboin JJ, Cha YI, Lu B. (2008b). Autophagy upregulation by inhibitors of caspase-3 and mTOR enhances radiotherapy in a mouse model of lung cancer. Autophagy 4: 659-668.
-
(2008)
Autophagy
, vol.4
, pp. 659-668
-
-
Kim, K.W.1
Hwang, M.2
Moretti, L.3
Jaboin, J.J.4
Cha, Y.I.5
Lu, B.6
-
75
-
-
70349694378
-
Combined Bcl-2/mammalian target of rapamycin inhibition leads to enhanced radiosensitization via induction of apoptosis and autophagy in non-small cell lung tumor xenograft model
-
Kim KW, Moretti L, Mitchell LR, Jung DK, Lu B. (2009b). Combined Bcl-2/mammalian target of rapamycin inhibition leads to enhanced radiosensitization via induction of apoptosis and autophagy in non-small cell lung tumor xenograft model. Clin Cancer Res 15: 6096-6105.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 6096-6105
-
-
Kim, K.W.1
Moretti, L.2
Mitchell, L.R.3
Jung, D.K.4
Lu, B.5
-
76
-
-
45049083880
-
Frameshift mutation of UVRAG, an autophagy-related gene, in gastric carcinomas with microsatellite instability
-
Kim MS, Jeong EG, Ahn CH, Kim SS, Lee SH, Yoo NJ. (2008a). Frameshift mutation of UVRAG, an autophagy-related gene, in gastric carcinomas with microsatellite instability. Hum Pathol 39: 1059-1063.
-
(2008)
Hum Pathol
, vol.39
, pp. 1059-1063
-
-
Kim, M.S.1
Jeong, E.G.2
Ahn, C.H.3
Kim, S.S.4
Lee, S.H.5
Yoo, N.J.6
-
77
-
-
58349098150
-
Arginine deiminase as a novel therapy for prostate cancer induces autophagy and caspase-independent apoptosis
-
Kim RH, Coates JM, Bowles TL, McNerney GP, Sutcliffe J, Jung JU et al. (2009a). Arginine deiminase as a novel therapy for prostate cancer induces autophagy and caspase-independent apoptosis. Cancer Res 69: 700-708.
-
(2009)
Cancer Res
, vol.69
, pp. 700-708
-
-
Kim, R.H.1
Coates, J.M.2
Bowles, T.L.3
McNerney, G.P.4
Sutcliffe, J.5
Jung, J.U.6
-
78
-
-
71549124671
-
Autophagy is activated by TGF-beta and potentiates TGF-beta-mediated growth inhibition in human hepatocellular carcinoma cells
-
Kiyono K, Suzuki HI, Matsuyama H, Morishita Y, Komuro A, Kano MR et al. (2009). Autophagy is activated by TGF-beta and potentiates TGF-beta-mediated growth inhibition in human hepatocellular carcinoma cells. Cancer Res 69: 8844-8852.
-
(2009)
Cancer Res
, vol.69
, pp. 8844-8852
-
-
Kiyono, K.1
Suzuki, H.I.2
Matsuyama, H.3
Morishita, Y.4
Komuro, A.5
Kano, M.R.6
-
79
-
-
77957252460
-
Tubular overexpression of transforming growth factor-beta1 induces autophagy and fibrosis but not mesenchymal transition of renal epithelial cells
-
Koesters R, Kaissling B, Lehir M, Picard N, Theilig F, Gebhardt R et al. (2010). Tubular overexpression of transforming growth factor-beta1 induces autophagy and fibrosis but not mesenchymal transition of renal epithelial cells. Am J Pathol 177: 632-643.
-
(2010)
Am J Pathol
, vol.177
, pp. 632-643
-
-
Koesters, R.1
Kaissling, B.2
Lehir, M.3
Picard, N.4
Theilig, F.5
Gebhardt, R.6
-
80
-
-
0037809355
-
KIP1) on malignant glioma cells
-
DOI 10.1038/sj.bjc.6600862
-
Komata T, Kanzawa T, Takeuchi H, Germano IM, Schreiber M, Kondo Y et al. (2003). Antitumour effect of cyclin-dependent kinase inhibitors (p16(INK4A), p18(INK4C), p19(INK4D), p21(WAF1/CIP1) and p27(KIP1)) on malignant glioma cells. Br J Cancer 88: 1277-1280. (Pubitemid 36606346)
-
(2003)
British Journal of Cancer
, vol.88
, Issue.8
, pp. 1277-1280
-
-
Komata, T.1
Kanzawa, T.2
Takeuchi, H.3
Germano, I.M.4
Schreiber, M.5
Kondo, Y.6
Kondo, S.7
-
81
-
-
77957993522
-
Beclin 1 over-and underexpression in colorectal cancer: Distinct patterns relate to prognosis and tumour hypoxia
-
Koukourakis MI, Giatromanolaki A, Sivridis E, Pitiakoudis M, Gatter KC, Harris AL. (2010). Beclin 1 over-and underexpression in colorectal cancer: distinct patterns relate to prognosis and tumour hypoxia. Br J Cancer 103: 1209-1214.
-
(2010)
Br J Cancer
, vol.103
, pp. 1209-1214
-
-
Koukourakis, M.I.1
Giatromanolaki, A.2
Sivridis, E.3
Pitiakoudis, M.4
Gatter, K.C.5
Harris, A.L.6
-
82
-
-
77951643083
-
ARD1 stabilization of TSC2 suppresses tumorigenesis through the mTOR signaling pathway
-
Kuo HP, Lee DF, Chen CT, Liu M, Chou CK, Lee HJ et al. (2010). ARD1 stabilization of TSC2 suppresses tumorigenesis through the mTOR signaling pathway. Sci Signal 3: ra9.
-
(2010)
Sci Signal
, vol.3
-
-
Kuo, H.P.1
Lee, D.F.2
Chen, C.T.3
Liu, M.4
Chou, C.K.5
Lee, H.J.6
-
83
-
-
67549135481
-
Cell death induced by dexamethasone in lymphoid leukemia is mediated through initiation of autophagy
-
Laane E, Tamm KP, Buentke E, Ito K, Kharaziha P, Oscarsson J et al. (2009). Cell death induced by dexamethasone in lymphoid leukemia is mediated through initiation of autophagy. Cell Death Differ 16: 1018-1029.
-
(2009)
Cell Death Differ
, vol.16
, pp. 1018-1029
-
-
Laane, E.1
Tamm, K.P.2
Buentke, E.3
Ito, K.4
Kharaziha, P.5
Oscarsson, J.6
-
84
-
-
74049101149
-
Autophagy in cutaneous malignant melanoma
-
Lazova R, Klump V, Pawelek J. (2010). Autophagy in cutaneous malignant melanoma. J Cutan Pathol 37: 256-268.
-
(2010)
J Cutan Pathol
, vol.37
, pp. 256-268
-
-
Lazova, R.1
Klump, V.2
Pawelek, J.3
-
85
-
-
70350776467
-
Why do melanomas get so dark?
-
Lazova R, Pawelek JM. (2009). Why do melanomas get so dark? Exp Dermatol 18: 934-938.
-
(2009)
Exp Dermatol
, vol.18
, pp. 934-938
-
-
Lazova, R.1
Pawelek, J.M.2
-
86
-
-
37649005234
-
Autophagy in the pathogenesis of disease
-
Levine B, Kroemer G. (2008). Autophagy in the pathogenesis of disease. Cell 132: 27-42.
-
(2008)
Cell
, vol.132
, pp. 27-42
-
-
Levine, B.1
Kroemer, G.2
-
87
-
-
78751672975
-
Autophagy in immunity and inflammation
-
Levine B, Mizushima N, Virgin HW. (2011). Autophagy in immunity and inflammation. Nature 469: 323-335.
-
(2011)
Nature
, vol.469
, pp. 323-335
-
-
Levine, B.1
Mizushima, N.2
Virgin, H.W.3
-
88
-
-
65249180744
-
The expression of beclin 1 is associated with favorable prognosis in stage IIIB colon cancers
-
Li BX, Li CY, Peng RQ, Wu XJ, Wang HY, Wan DS et al. (2009). The expression of beclin 1 is associated with favorable prognosis in stage IIIB colon cancers. Autophagy 5: 303-306.
-
(2009)
Autophagy
, vol.5
, pp. 303-306
-
-
Li, B.X.1
Li, C.Y.2
Peng, R.Q.3
Wu, X.J.4
Wang, H.Y.5
Wan, D.S.6
-
89
-
-
77955038334
-
The epidermal growth factor receptor antibody cetuximab induces autophagy in cancer cells by downregulating HIF-1alpha and Bcl-2 and activating the beclin 1/hVps34 complex
-
Li X, Fan Z. (2010). The epidermal growth factor receptor antibody cetuximab induces autophagy in cancer cells by downregulating HIF-1alpha and Bcl-2 and activating the beclin 1/hVps34 complex. Cancer Res 70: 5942-5952.
-
(2010)
Cancer Res
, vol.70
, pp. 5942-5952
-
-
Li, X.1
Fan, Z.2
-
90
-
-
77952272127
-
Genetic and epigenetic silencing of the beclin 1 gene in sporadic breast tumors
-
Li Z, Chen B, Wu Y, Jin F, Xia Y, Liu X. (2010). Genetic and epigenetic silencing of the beclin 1 gene in sporadic breast tumors. BMC Cancer 10: 98.
-
(2010)
BMC Cancer
, vol.10
, pp. 98
-
-
Li, Z.1
Chen, B.2
Wu, Y.3
Jin, F.4
Xia, Y.5
Liu, X.6
-
91
-
-
78650170269
-
A natural BH3 mimetic induces autophagy in apoptosis-resistant prostate cancer via modulating Bcl-2-Beclin1 interaction at endoplasmic reticulum
-
Lian J, Wu X, He F, Karnak D, Tang W, Meng Y et al. (2011). A natural BH3 mimetic induces autophagy in apoptosis-resistant prostate cancer via modulating Bcl-2-Beclin1 interaction at endoplasmic reticulum. Cell Death Differ 18: 60-71.
-
(2011)
Cell Death Differ
, vol.18
, pp. 60-71
-
-
Lian, J.1
Wu, X.2
He, F.3
Karnak, D.4
Tang, W.5
Meng, Y.6
-
92
-
-
33947250696
-
kip1 phosphorylation mediating the decision to enter autophagy or apoptosis
-
DOI 10.1038/ncb1537, PII NCB1537
-
Liang J, Shao SH, Xu ZX, Hennessy B, Ding Z, LarreaMet al. (2007). The energy sensing LKB1-AMPK pathway regulates p27(kip1) phosphorylation mediating the decision to enter autophagy or apoptosis. Nat Cell Biol 9: 218-224. (Pubitemid 46420865)
-
(2007)
Nature Cell Biology
, vol.9
, Issue.2
, pp. 218-224
-
-
Liang, J.1
Shao, S.H.2
Xu, Z.-X.3
Hennessy, B.4
Ding, Z.5
Larrea, M.6
Kondo, S.7
Dumont, D.J.8
Gutterman, J.U.9
Walker, C.L.10
Slingerland, J.M.11
Mills, G.B.12
-
93
-
-
80051479542
-
Activation of mammalian target of rapamycin pathway confers adverse outcome in nonsmall cell lung carcinoma
-
doi:10.1002/cncr.25959)
-
Liu D, Huang Y, Chen B, Zeng J, Guo N, Zhang S et al. (2011). Activation of mammalian target of rapamycin pathway confers adverse outcome in nonsmall cell lung carcinoma. Cancer (doi:10.1002/cncr.25959).
-
(2011)
Cancer
-
-
Liu, D.1
Huang, Y.2
Chen, B.3
Zeng, J.4
Guo, N.5
Zhang, S.6
-
94
-
-
78751511180
-
Autophagy facilitates glycolysis during Ras-mediated oncogenic transformation
-
Lock R, Roy S, Kenific CM, Su JS, Salas E, Ronen SM et al. (2011). Autophagy facilitates glycolysis during Ras-mediated oncogenic transformation. Mol Biol Cell 22: 165-178.
-
(2011)
Mol Biol Cell
, vol.22
, pp. 165-178
-
-
Lock, R.1
Roy, S.2
Kenific, C.M.3
Su, J.S.4
Salas, E.5
Ronen, S.M.6
-
95
-
-
70149114818
-
C-Jun NH2-terminal kinase activation is essential for DRAM-dependent induction of autophagy and apoptosis in 2-methoxyestradiol-treated Ewing sarcoma cells
-
Lorin S, Borges A, Ribeiro Dos Santos L, Souquere S, Pierron G, Ryan KM et al. (2009). c-Jun NH2-terminal kinase activation is essential for DRAM-dependent induction of autophagy and apoptosis in 2-methoxyestradiol- treated Ewing sarcoma cells. Cancer Res 69: 6924-6931.
-
(2009)
Cancer Res
, vol.69
, pp. 6924-6931
-
-
Lorin, S.1
Borges, A.2
Ribeiro Dos Santos, L.3
Souquere, S.4
Pierron, G.5
Ryan, K.M.6
-
96
-
-
75149146637
-
Evidence for the interplay between JNK and p53-DRAM signalling pathways in the regulation of autophagy
-
Lorin S, Pierron G, Ryan KM, Codogno P, Djavaheri-Mergny M. (2010). Evidence for the interplay between JNK and p53-DRAM signalling pathways in the regulation of autophagy. Autophagy 6: 153-154.
-
(2010)
Autophagy
, vol.6
, pp. 153-154
-
-
Lorin, S.1
Pierron, G.2
Ryan, K.M.3
Codogno, P.4
Djavaheri-Mergny, M.5
-
97
-
-
60549098630
-
Differential RelA-and RelB-dependent gene transcription in LTbetaR-stimulated mouse embryonic fibroblasts
-
Lovas A, Radke D, Albrecht D, Yilmaz ZB, Moller U, Habenicht AJ et al. (2008). Differential RelA-and RelB-dependent gene transcription in LTbetaR-stimulated mouse embryonic fibroblasts. BMC Genomics 9: 606.
-
(2008)
BMC Genomics
, vol.9
, pp. 606
-
-
Lovas, A.1
Radke, D.2
Albrecht, D.3
Yilmaz, Z.B.4
Moller, U.5
Habenicht, A.J.6
-
98
-
-
57449121645
-
The tumor suppressor gene ARHI regulates autophagy and tumor dormancy in human ovarian cancer cells
-
Lu Z, Luo RZ, Lu Y, Zhang X, Yu Q, Khare S et al. (2008). The tumor suppressor gene ARHI regulates autophagy and tumor dormancy in human ovarian cancer cells. J Clin Invest 118: 3917-3929.
-
(2008)
J Clin Invest
, vol.118
, pp. 3917-3929
-
-
Lu, Z.1
Luo, R.Z.2
Lu, Y.3
Zhang, X.4
Yu, Q.5
Khare, S.6
-
99
-
-
12944303650
-
Growth factor regulation of autophagy and cell survival in the absence of apoptosis
-
DOI 10.1016/j.cell.2004.11.046, PII S009286740401150X
-
Lum JJ, Bauer DE, Kong M, Harris MH, Li C, Lindsten T et al. (2005). Growth factor regulation of autophagy and cell survival in the absence of apoptosis. Cell 120: 237-248. (Pubitemid 40174766)
-
(2005)
Cell
, vol.120
, Issue.2
, pp. 237-248
-
-
Lum, J.J.1
Bauer, D.E.2
Kong, M.3
Harris, M.H.4
Li, C.5
Lindsten, T.6
Thompson, C.B.7
-
100
-
-
79956003662
-
Measurements of tumor cell autophagy predict invasiveness, resistance to chemotherapy, and survival in melanoma
-
Ma X, Piao S, Wang DW, McAfee QW, Nathanson KL, Lum JJ et al. (2011). Measurements of tumor cell autophagy predict invasiveness, resistance to chemotherapy, and survival in melanoma. Clin Cancer Res 17: 1-12.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 1-12
-
-
Ma, X.1
Piao, S.2
Wang, D.W.3
McAfee, Q.W.4
Nathanson, K.L.5
Lum, J.J.6
-
101
-
-
77952428054
-
Induction of autophagy and inhibition of melanoma growth in vitro and in vivo by hyperactivation of oncogenic BRAF
-
Maddodi N, Huang W, Havighurst T, Kim K, Longley BJ, Setaluri V. (2010). Induction of autophagy and inhibition of melanoma growth in vitro and in vivo by hyperactivation of oncogenic BRAF. J Invest Dermatol 130: 1657-1667.
-
(2010)
J Invest Dermatol
, vol.130
, pp. 1657-1667
-
-
Maddodi, N.1
Huang, W.2
Havighurst, T.3
Kim, K.4
Longley, B.J.5
Setaluri, V.6
-
102
-
-
34250894388
-
BH3-only proteins and BH3 mimetics induce autophagy by competitively disrupting the interaction between Beclin 1 and Bcl-2/Bcl-X(L
-
Maiuri MC, Criollo A, Tasdemir E, Vicencio JM, Tajeddine N, Hickman JA et al. (2007a). BH3-only proteins and BH3 mimetics induce autophagy by competitively disrupting the interaction between Beclin 1 and Bcl-2/Bcl-X(L). Autophagy 3: 374-346.
-
(2007)
Autophagy
, vol.3
, pp. 374-346
-
-
Maiuri, M.C.1
Criollo, A.2
Tasdemir, E.3
Vicencio, J.M.4
Tajeddine, N.5
Hickman, J.A.6
-
103
-
-
77951243028
-
Autophagy regulation by p53
-
Maiuri MC, Galluzzi L, Morselli E, Kepp O, Malik SA, Kroemer G. (2010). Autophagy regulation by p53. Curr Opin Cell Biol 22: 181-185.
-
(2010)
Curr Opin Cell Biol
, vol.22
, pp. 181-185
-
-
Maiuri, M.C.1
Galluzzi, L.2
Morselli, E.3
Kepp, O.4
Malik, S.A.5
Kroemer, G.6
-
104
-
-
34248998801
-
L and a BH3-like domain in Beclin-1
-
DOI 10.1038/sj.emboj.7601689, PII 7601689
-
Maiuri MC, Le Toumelin G, Criollo A, Rain JC, Gautier F, Juin P et al. (2007b). Functional and physical interaction between Bcl-X(L) and a BH3-like domain in Beclin-1. EMBO J 26: 2527-2539. (Pubitemid 46788315)
-
(2007)
EMBO Journal
, vol.26
, Issue.10
, pp. 2527-2539
-
-
Maiuri, M.C.1
Le Toumelin, G.2
Criollo, A.3
Rain, J.-C.4
Gautier, F.5
Juin, P.6
Tasdemir, E.7
Pierron, G.8
Troulinaki, K.9
Tavernarakis, N.10
Hickman, J.A.11
Geneste, O.12
Kroemer, G.13
-
105
-
-
66849111716
-
Stimulation of autophagy by the p53 target gene Sestrin2
-
Maiuri MC, Malik SA, Morselli E, Kepp O, Criollo A, Mouchel PL et al. (2009). Stimulation of autophagy by the p53 target gene Sestrin2. Cell Cycle 8: 1571-1576.
-
(2009)
Cell Cycle
, vol.8
, pp. 1571-1576
-
-
Maiuri, M.C.1
Malik, S.A.2
Morselli, E.3
Kepp, O.4
Criollo, A.5
Mouchel, P.L.6
-
106
-
-
34547132328
-
Tissue-specific autophagy alterations and increased tumorigenesis in mice deficient in Atg4C/autophagin-3
-
DOI 10.1074/jbc.M701194200
-
Marino G, Salvador-Montoliu N, Fueyo A, Knecht E, Mizushima N, Lopez-Otin C. (2007). Tissue-specific autophagy alterations and increased tumorigenesis in mice deficient in Atg4C/autophagin-3. J Biol Chem 282: 18573-18583. (Pubitemid 47100226)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.25
, pp. 18573-18583
-
-
Marino, G.1
Salvador-Montoliu, N.2
Fueyo, A.3
Knecht, E.4
Mizushima, N.5
Lopez-Otin, C.6
-
107
-
-
34249863298
-
Autophagy suppresses tumor progression by limiting chromosomal instability
-
DOI 10.1101/gad.1545107
-
Mathew R, Kongara S, Beaudoin B, Karp CM, Bray K, Degenhardt K et al. (2007). Autophagy suppresses tumor progression by limiting chromosomal instability. Genes Dev 21: 1367-1381. (Pubitemid 46871040)
-
(2007)
Genes and Development
, vol.21
, Issue.11
, pp. 1367-1381
-
-
Mathew, R.1
Kongara, S.2
Beaudoin, B.3
Karp, C.M.4
Bray, K.5
Degenhardt, K.6
Chen, G.7
Jin, S.8
White, E.9
-
108
-
-
34848896271
-
Galectin-1 knockdown increases sensitivity to temozolomide in a B16F10 mouse metastatic melanoma model
-
DOI 10.1038/sj.jid.5700869, PII 5700869
-
Mathieu V, Le Mercier M, De Neve N, Sauvage S, Gras T, Roland I et al. (2007). Galectin-1 knockdown increases sensitivity to temozolomide in a B16F10 mouse metastatic melanoma model. J Invest Dermatol 127: 2399-2410. (Pubitemid 47619747)
-
(2007)
Journal of Investigative Dermatology
, vol.127
, Issue.10
, pp. 2399-2410
-
-
Mathieu, V.1
Le Mercier, M.2
De Neve, N.3
Sauvage, S.4
Gras, T.5
Roland, I.6
Lefranc, F.7
Kiss, R.8
-
109
-
-
77953948764
-
Activation of autophagy during cell death requires the engulfment receptor Draper
-
McPhee CK, Logan MA, Freeman MR, Baehrecke EH. (2010). Activation of autophagy during cell death requires the engulfment receptor Draper. Nature 465: 1093-1096.
-
(2010)
Nature
, vol.465
, pp. 1093-1096
-
-
McPhee, C.K.1
Logan, M.A.2
Freeman, M.R.3
Baehrecke, E.H.4
-
110
-
-
58149104056
-
The plant alkaloid voacamine induces apoptosis-independent autophagic cell death on both sensitive and multidrug resistant human osteosarcoma cells
-
Meschini S, Condello M, Calcabrini A, Marra M, Formisano G, Lista P et al. (2008). The plant alkaloid voacamine induces apoptosis-independent autophagic cell death on both sensitive and multidrug resistant human osteosarcoma cells. Autophagy 4: 1020-1033.
-
(2008)
Autophagy
, vol.4
, pp. 1020-1033
-
-
Meschini, S.1
Condello, M.2
Calcabrini, A.3
Marra, M.4
Formisano, G.5
Lista, P.6
-
111
-
-
77954134159
-
GABARAP is overexpressed in colorectal carcinoma and correlates with shortened patient survival
-
Miao Y, Zhang Y, Chen Y, Chen L, Wang F. (2010). GABARAP is overexpressed in colorectal carcinoma and correlates with shortened patient survival. Hepatogastroenterology 57: 257-261.
-
(2010)
Hepatogastroenterology
, vol.57
, pp. 257-261
-
-
Miao, Y.1
Zhang, Y.2
Chen, Y.3
Chen, L.4
Wang, F.5
-
112
-
-
77649335850
-
Beclin 1 and LC3 autophagic gene expression in cutaneous melanocytic lesions
-
Miracco C, Cevenini G, Franchi A, Luzi P, Cosci E, Mourmouras V et al. (2010). Beclin 1 and LC3 autophagic gene expression in cutaneous melanocytic lesions. Hum Pathol 41: 503-512.
-
(2010)
Hum Pathol
, vol.41
, pp. 503-512
-
-
Miracco, C.1
Cevenini, G.2
Franchi, A.3
Luzi, P.4
Cosci, E.5
Mourmouras, V.6
-
113
-
-
34047271129
-
Protein and mRNA expression of autophagy gene Beclin 1 in human brain tumours
-
Miracco C, Cosci E, Oliveri G, Luzi P, Pacenti L, Monciatti I et al. (2007). Protein and mRNA expression of autophagy gene Beclin 1 in human brain tumours. Int J Oncol 30: 429-436.
-
(2007)
Int J Oncol
, vol.30
, pp. 429-436
-
-
Miracco, C.1
Cosci, E.2
Oliveri, G.3
Luzi, P.4
Pacenti, L.5
Monciatti, I.6
-
114
-
-
39849109338
-
Autophagy fights disease through cellular self-digestion
-
DOI 10.1038/nature06639, PII NATURE06639
-
Mizushima N, Levine B, Cuervo AM, Klionsky DJ. (2008). Autophagy fights disease through cellular self-digestion. Nature 451: 1069-1075. (Pubitemid 351317450)
-
(2008)
Nature
, vol.451
, Issue.7182
, pp. 1069-1075
-
-
Mizushima, N.1
Levine, B.2
Cuervo, A.M.3
Klionsky, D.J.4
-
115
-
-
53649086181
-
Mutant p53 protein localized in the cytoplasm inhibits autophagy
-
Morselli E, Tasdemir E, Maiuri MC, Galluzzi L, Kepp O, Criollo A et al. (2008). Mutant p53 protein localized in the cytoplasm inhibits autophagy. Cell Cycle 7: 3056-3061.
-
(2008)
Cell Cycle
, vol.7
, pp. 3056-3061
-
-
Morselli, E.1
Tasdemir, E.2
Maiuri, M.C.3
Galluzzi, L.4
Kepp, O.5
Criollo, A.6
-
116
-
-
70349644004
-
Autophagy facilitates oncogene-induced senescence
-
Narita M, Young AR. (2009). Autophagy facilitates oncogene-induced senescence. Autophagy 5: 1046-1047.
-
(2009)
Autophagy
, vol.5
, pp. 1046-1047
-
-
Narita, M.1
Young, A.R.2
-
117
-
-
77957861637
-
Chromosome band 17q21 in breast cancer: Significant association between beclin 1 loss and HER2/NEU amplification
-
Negri T, Tarantino E, Orsenigo M, Reid JF, GariboldiM, ZambettiM et al. (2010). Chromosome band 17q21 in breast cancer: significant association between beclin 1 loss and HER2/NEU amplification. Genes Chromosomes Cancer 49: 901-909.
-
(2010)
Genes Chromosomes Cancer
, vol.49
, pp. 901-909
-
-
Negri, T.1
Tarantino, E.2
Orsenigo, M.3
Reid, J.F.4
Gariboldi, M.5
Zambetti, M.6
-
118
-
-
70349687405
-
Discovery of Atg5/Atg7-independent alternative macroautophagy
-
Nishida Y, Arakawa S, Fujitani K, Yamaguchi H, Mizuta T, Kanaseki T et al. (2009). Discovery of Atg5/Atg7-independent alternative macroautophagy. Nature 461: 654-658.
-
(2009)
Nature
, vol.461
, pp. 654-658
-
-
Nishida, Y.1
Arakawa, S.2
Fujitani, K.3
Yamaguchi, H.4
Mizuta, T.5
Kanaseki, T.6
-
119
-
-
69449084241
-
Autophagy activation by NFkappaB is essential for cell survival after heat shock
-
Nivon M, Richet E, Codogno P, Arrigo AP, Kretz-Remy C. (2009). Autophagy activation by NFkappaB is essential for cell survival after heat shock. Autophagy 5: 766-783.
-
(2009)
Autophagy
, vol.5
, pp. 766-783
-
-
Nivon, M.1
Richet, E.2
Codogno, P.3
Arrigo, A.P.4
Kretz-Remy, C.5
-
120
-
-
54449099779
-
Bcl-xL and UVRAG cause a monomer-dimer switch in Beclin1
-
Noble CG, Dong JM, Manser E, Song H. (2008). Bcl-xL and UVRAG cause a monomer-dimer switch in Beclin1. J Biol Chem 283: 26274-26282.
-
(2008)
J Biol Chem
, vol.283
, pp. 26274-26282
-
-
Noble, C.G.1
Dong, J.M.2
Manser, E.3
Song, H.4
-
121
-
-
56249119507
-
Overexpression and altered subcellular localization of autophagy-related 16-like 1 in human oral squamous-cell carcinoma: Correlation with lymphovascular invasion and lymph-node metastasis
-
Nomura H, Uzawa K, Yamano Y, Fushimi K, Ishigami T, Kouzu Y et al. (2009). Overexpression and altered subcellular localization of autophagy-related 16-like 1 in human oral squamous-cell carcinoma: correlation with lymphovascular invasion and lymph-node metastasis. Hum Pathol 40: 83-91.
-
(2009)
Hum Pathol
, vol.40
, pp. 83-91
-
-
Nomura, H.1
Uzawa, K.2
Yamano, Y.3
Fushimi, K.4
Ishigami, T.5
Kouzu, Y.6
-
122
-
-
79955676537
-
Induction of autophagy by drug-resistant esophageal cancer cells promotes their survival and recovery following treatment with chemotherapeutics
-
O'Donovan TR, O'Sullivan GC, McKenna S. (2011). Induction of autophagy by drug-resistant esophageal cancer cells promotes their survival and recovery following treatment with chemotherapeutics. Autophagy 7: 509-524.
-
(2011)
Autophagy
, vol.7
, pp. 509-524
-
-
O'Donovan, T.R.1
O'Sullivan, G.C.2
McKenna, S.3
-
123
-
-
43949093441
-
Anti-cancer agent siramesine is a lysosomotropic detergent that induces cytoprotective autophagosome accumulation
-
Ostenfeld MS, Hoyer-Hansen M, Bastholm L, Fehrenbacher N, Olsen OD, Groth-Pedersen L et al. (2008). Anti-cancer agent siramesine is a lysosomotropic detergent that induces cytoprotective autophagosome accumulation. Autophagy 4: 487-499. (Pubitemid 351705145)
-
(2008)
Autophagy
, vol.4
, Issue.4
, pp. 487-499
-
-
Ostenfeld, M.S.1
Hoyer-Hansen, M.2
Bastholm, L.3
Fehrenbacher, N.4
Olsen, O.D.5
Groth-Pedersen, L.6
Puustinen, P.7
Kirkegaard-Sorensen, T.8
Nylandsted, J.9
Farkas, T.10
Jaattela, M.11
-
124
-
-
68049094818
-
Immunohistochemical expression of MAP1LC3A and MAP1LC3B protein in breast carcinoma tissues
-
Othman EQ, Kaur G, Mutee AF, Muhammad TS, Tan ML. (2009). Immunohistochemical expression of MAP1LC3A and MAP1LC3B protein in breast carcinoma tissues. J Clin Lab Anal 23: 249-258.
-
(2009)
J Clin Lab Anal
, vol.23
, pp. 249-258
-
-
Othman, E.Q.1
Kaur, G.2
Mutee, A.F.3
Muhammad, T.S.4
Tan, M.L.5
-
125
-
-
28244475972
-
Rapamycin-sensitive pathway regulates mitochondrial membrane potential, autophagy, and survival in irradiated MCF-7 cells
-
DOI 10.1158/0008-5472.CAN-05-1083
-
Paglin S, Lee NY, Nakar C, Fitzgerald M, Plotkin J, Deuel B et al. (2005). Rapamycin-sensitive pathway regulates mitochondrial membrane potential, autophagy, and survival in irradiated MCF-7 cells. Cancer Res 65: 11061-11070. (Pubitemid 41713377)
-
(2005)
Cancer Research
, vol.65
, Issue.23
, pp. 11061-11070
-
-
Paglin, S.1
Lee, N.-Y.2
Nakar, C.3
Fitzgerald, M.4
Plotkin, J.5
Deuel, B.6
Hackett, N.7
McMahill, M.8
Sphicas, E.9
Lampen, N.10
Yahalom, J.11
-
126
-
-
76149086512
-
FYCO1 is a Rab7 effector that binds to LC3 and PI3P to mediate microtubule plus end-directed vesicle transport
-
Pankiv S, Alemu EA, Brech A, Bruun JA, Lamark T, Overvatn A et al. (2010). FYCO1 is a Rab7 effector that binds to LC3 and PI3P to mediate microtubule plus end-directed vesicle transport. J Cell Biol 188: 253-269.
-
(2010)
J Cell Biol
, vol.188
, pp. 253-269
-
-
Pankiv, S.1
Alemu, E.A.2
Brech, A.3
Bruun, J.A.4
Lamark, T.5
Overvatn, A.6
-
127
-
-
77953708505
-
FYCO1: Linking autophagosomes to microtubule plus end-directing molecular motors
-
Pankiv S, Johansen T. (2010). FYCO1: linking autophagosomes to microtubule plus end-directing molecular motors. Autophagy 6: 550-552.
-
(2010)
Autophagy
, vol.6
, pp. 550-552
-
-
Pankiv, S.1
Johansen, T.2
-
128
-
-
41149155977
-
OSU-03012 stimulates PKR-like endoplasmic reticulum-dependent increases in 70-kDa heat shock protein expression, attenuating its lethal actions in transformed cells
-
DOI 10.1124/mol.107.042697
-
Park MA, Yacoub A, Rahmani M, Zhang G, Hart L, Hagan MP et al. (2008). OSU-03012 stimulates PKR-like endoplasmic reticulumdependent increases in 70-kDa heat shock protein expression, attenuating its lethal actions in transformed cells. Mol Pharmacol 73: 1168-1184. (Pubitemid 351439199)
-
(2008)
Molecular Pharmacology
, vol.73
, Issue.4
, pp. 1168-1184
-
-
Park, M.A.1
Yacoub, A.2
Rahmani, M.3
Zhang, G.4
Hart, L.5
Hagan, M.P.6
Calderwood, S.K.7
Sherman, M.Y.8
Koumenis, C.9
Spiegel, S.10
Chen, C.-S.11
Graf, M.12
Curiel, D.T.13
Fisher, P.B.14
Grant, S.15
Dent, P.16
-
129
-
-
25144457455
-
Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy
-
DOI 10.1016/j.cell.2005.07.002, PII S0092867405006926
-
Pattingre S, Tassa A, Qu X, Garuti R, Liang XH, Mizushima N et al. (2005). Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy. Cell 122: 927-939. (Pubitemid 41345209)
-
(2005)
Cell
, vol.122
, Issue.6
, pp. 927-939
-
-
Pattingre, S.1
Tassa, A.2
Qu, X.3
Garuti, R.4
Xiao, H.L.5
Mizushima, N.6
Packer, M.7
Schneider, M.D.8
Levine, B.9
-
130
-
-
70349649219
-
The prognostic role of Beclin 1 protein expression in highgrade gliomas
-
Pirtoli L, Cevenini G, Tini P, Vannini M, Oliveri G, Marsili S et al. (2009). The prognostic role of Beclin 1 protein expression in highgrade gliomas. Autophagy 5: 930-936.
-
(2009)
Autophagy
, vol.5
, pp. 930-936
-
-
Pirtoli, L.1
Cevenini, G.2
Tini, P.3
Vannini, M.4
Oliveri, G.5
Marsili, S.6
-
131
-
-
70349667473
-
Spectrum of phosphatidylinositol 3-kinase pathway gene alterations in bladder cancer
-
Platt FM, Hurst CD, Taylor CF, Gregory WM, Harnden P, Knowles MA. (2009). Spectrum of phosphatidylinositol 3-kinase pathway gene alterations in bladder cancer. Clin Cancer Res 15: 6008-6017.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 6008-6017
-
-
Platt, F.M.1
Hurst, C.D.2
Taylor, C.F.3
Gregory, W.M.4
Harnden, P.5
Knowles, M.A.6
-
132
-
-
49649121765
-
E2F1 regulates autophagy and the transcription of autophagy genes
-
Polager S, Ofir M, Ginsberg D. (2008). E2F1 regulates autophagy and the transcription of autophagy genes. Oncogene 27: 4860-4864.
-
(2008)
Oncogene
, vol.27
, pp. 4860-4864
-
-
Polager, S.1
Ofir, M.2
Ginsberg, D.3
-
133
-
-
79251517741
-
The CD40-autophagy pathway is needed for host protection despite IFN-Gamma-dependent immunity and CD40 induces autophagy via control of P21 levels
-
Portillo JA, Okenka G, Reed E, Subauste A, Van Grol J, Gentil K et al. (2010). The CD40-autophagy pathway is needed for host protection despite IFN-Gamma-dependent immunity and CD40 induces autophagy via control of P21 levels. PLoS One 5: e14472.
-
(2010)
PLoS One
, vol.5
-
-
Portillo, J.A.1
Okenka, G.2
Reed, E.3
Subauste, A.4
Van Grol, J.5
Gentil, K.6
-
134
-
-
56549116658
-
Macroautophagy inhibition sensitizes tamoxifen-resistant breast cancer cells and enhances mitochondrial depolarization
-
Qadir MA, Kwok B, Dragowska WH, To KH, Le D, Bally MB et al. (2008). Macroautophagy inhibition sensitizes tamoxifen-resistant breast cancer cells and enhances mitochondrial depolarization. Breast Cancer Res Treat 112: 389-403.
-
(2008)
Breast Cancer Res Treat
, vol.112
, pp. 389-403
-
-
Qadir, M.A.1
Kwok, B.2
Dragowska, W.H.3
To, K.H.4
Le Bally D, M.B.5
-
135
-
-
53549087505
-
Nucleolar p19ARF, unlike mitochondrial smARF, is incapable of inducing p53-independent autophagy
-
Reef S, Kimchi A. (2008). Nucleolar p19ARF, unlike mitochondrial smARF, is incapable of inducing p53-independent autophagy. Autophagy 4: 866-869.
-
(2008)
Autophagy
, vol.4
, pp. 866-869
-
-
Reef, S.1
Kimchi, A.2
-
136
-
-
35348853088
-
The autophagic inducer smARF interacts with and is stabilized by the mitochondrial p32 protein
-
DOI 10.1038/sj.onc.1210485, PII 1210485
-
Reef S, Shifman O, Oren M, Kimchi A. (2007). The autophagic inducer smARF interacts with and is stabilized by the mitochondrial p32 protein. Oncogene 26: 6677-6683. (Pubitemid 47573682)
-
(2007)
Oncogene
, vol.26
, Issue.46
, pp. 6677-6683
-
-
Reef, S.1
Shifman, O.2
Oren, M.3
Kimchi, A.4
-
137
-
-
33646523798
-
A short mitochondrial form of p19ARF induces autophagy and caspase-independent cell death
-
Reef S, Zalckvar E, Shifman O, Bialik S, Sabanay H, Oren M et al. (2006). A short mitochondrial form of p19ARF induces autophagy and caspase-independent cell death. Mol Cell 22: 463-475.
-
(2006)
Mol Cell
, vol.22
, pp. 463-475
-
-
Reef, S.1
Zalckvar, E.2
Shifman, O.3
Bialik, S.4
Sabanay, H.5
Oren, M.6
-
138
-
-
53549127988
-
CCL2 protects prostate cancer PC3 cells from autophagic death via phosphatidylinositol 3-kinase/AKT-dependent survivin up-regulation
-
Roca H, Varsos Z, Pienta KJ. (2008). CCL2 protects prostate cancer PC3 cells from autophagic death via phosphatidylinositol 3-kinase/AKT-dependent survivin up-regulation. J Biol Chem 283: 25057-25073.
-
(2008)
J Biol Chem
, vol.283
, pp. 25057-25073
-
-
Roca, H.1
Varsos, Z.2
Pienta, K.J.3
-
139
-
-
0025087287
-
Allele loss from chromosome 17 in ovarian cancer
-
Russell SE, Hickey GI, Lowry WS, White P, Atkinson RJ. (1990). Allele loss from chromosome 17 in ovarian cancer. Oncogene 5: 1581-1583.
-
(1990)
Oncogene
, vol.5
, pp. 1581-1583
-
-
Russell, S.E.1
Hickey, G.I.2
Lowry, W.S.3
White, P.4
Atkinson, R.J.5
-
140
-
-
0027217756
-
Detailed deletion mapping of chromosome 17q in ovarian and breast cancers: 2-cM Region on 17q21.3 often and commonly deleted in tumors
-
Saito H, Inazawa J, Saito S, Kasumi F, Koi S, Sagae S et al. (1993). Detailed deletion mapping of chromosome 17q in ovarian and breast cancers: 2-cM region on 17q21.3 often and commonly deleted in tumors. Cancer Res 53: 3382-3385. (Pubitemid 23223313)
-
(1993)
Cancer Research
, vol.53
, Issue.14
, pp. 3382-3385
-
-
Saito, H.1
Inazawa, J.2
Saito, S.3
Kasumi, F.4
Koi, S.5
Sagae, S.6
Kudo, R.7
Saito, J.8
Noda, K.9
Nakamura, Y.10
-
141
-
-
37149042642
-
A role for LKB1 gene in human cancer beyond the Peutz-Jeghers syndrome
-
DOI 10.1038/sj.onc.1210594, PII 1210594
-
Sanchez-Cespedes M. (2007). A role for LKB1 gene in human cancer beyond the Peutz-Jeghers syndrome. Oncogene 26: 7825-7832. (Pubitemid 350261789)
-
(2007)
Oncogene
, vol.26
, Issue.57
, pp. 7825-7832
-
-
Sanchez-Cespedes, M.1
-
142
-
-
47249094223
-
Role of non-canonical Beclin 1-independent autophagy in cell death induced by resveratrol in human breast cancer cells
-
DOI 10.1038/cdd.2008.51, PII CDD200851
-
Scarlatti F, Maffei R, Beau I, Codogno P, Ghidoni R. (2008). Role of non-canonical Beclin 1-independent autophagy in cell death induced by resveratrol in human breast cancer cells. Cell Death Differ 15: 1318-1329. (Pubitemid 351984760)
-
(2008)
Cell Death and Differentiation
, vol.15
, Issue.8
, pp. 1318-1329
-
-
Scarlatti, F.1
Maffei, R.2
Beau, I.3
Codogno, P.4
Ghidoni, R.5
-
143
-
-
78649833334
-
P53-dependent regulation of autophagy protein LC3 supports cancer cell survival under prolonged starvation
-
Scherz-Shouval R, Weidberg H, Gonen C, Wilder S, Elazar Z, Oren M. (2010). p53-dependent regulation of autophagy protein LC3 supports cancer cell survival under prolonged starvation. Proc Natl Acad Sci USA 107: 18511-18516.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 18511-18516
-
-
Scherz-Shouval, R.1
Weidberg, H.2
Gonen, C.3
Wilder, S.4
Elazar, Z.5
Oren, M.6
-
144
-
-
0030944985
-
Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16(INK4a)
-
DOI 10.1016/S0092-8674(00)81902-9
-
Serrano M, Lin AW, McCurrach ME, Beach D, Lowe SW. (1997). Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a. Cell 88: 593-602. (Pubitemid 27152402)
-
(1997)
Cell
, vol.88
, Issue.5
, pp. 593-602
-
-
Serrano, M.1
Lin, A.W.2
McCurrach, M.E.3
Beach, D.4
Lowe, S.W.5
-
145
-
-
58749088233
-
Inhibition of autophagy at a late stage enhances imatinib-induced cytotoxicity in human malignant glioma cells
-
Shingu T, Fujiwara K, Bogler O, Akiyama Y, Moritake K, Shinojima N et al. (2009). Inhibition of autophagy at a late stage enhances imatinib-induced cytotoxicity in human malignant glioma cells. Int J Cancer 124: 1060-1071.
-
(2009)
Int J Cancer
, vol.124
, pp. 1060-1071
-
-
Shingu, T.1
Fujiwara, K.2
Bogler, O.3
Akiyama, Y.4
Moritake, K.5
Shinojima, N.6
-
146
-
-
77952040472
-
LC3A-positive light microscopy detected patterns of autophagy and prognosis in operable breast carcinomas
-
Sivridis E, Koukourakis MI, Zois CE, Ledaki I, Ferguson DJ, Harris AL et al. (2010). LC3A-positive light microscopy detected patterns of autophagy and prognosis in operable breast carcinomas. Am J Pathol 176: 2477-2489.
-
(2010)
Am J Pathol
, vol.176
, pp. 2477-2489
-
-
Sivridis, E.1
Koukourakis, M.I.2
Zois, C.E.3
Ledaki, I.4
Ferguson, D.J.5
Harris, A.L.6
-
147
-
-
73549084068
-
Thiazolidinediones induce Rab7-RILPMAPK-dependent juxtanuclear lysosome aggregation and reduce tumor cell invasion
-
Steffan JJ, Cardelli JA. (2010). Thiazolidinediones induce Rab7-RILPMAPK-dependent juxtanuclear lysosome aggregation and reduce tumor cell invasion. Traffic 11: 274-286.
-
(2010)
Traffic
, vol.11
, pp. 274-286
-
-
Steffan, J.J.1
Cardelli, J.A.2
-
148
-
-
77951165622
-
HGFinduced invasion by prostate tumor cells requires anterograde lysosome trafficking and activity of Na+-H+ exchangers
-
Steffan JJ, Williams BC, Welbourne T, Cardelli JA. (2010). HGFinduced invasion by prostate tumor cells requires anterograde lysosome trafficking and activity of Na+-H+ exchangers. J Cell Sci 123: 1151-1159.
-
(2010)
J Cell Sci
, vol.123
, pp. 1151-1159
-
-
Steffan, J.J.1
Williams, B.C.2
Welbourne, T.3
Cardelli, J.A.4
-
149
-
-
78449300668
-
How a lipid mediates tumour suppression
-
The Sir Hans Krebs Lecture Delivered on 29 June 2010 at the 35th FEBS Congress in Gothenburg, Sweden
-
Stenmark H. (2010). The Sir Hans Krebs Lecture. How a lipid mediates tumour suppression. Delivered on 29 June 2010 at the 35th FEBS Congress in Gothenburg, Sweden. FEBS J 277: 4837-4848.
-
(2010)
FEBS J
, vol.277
, pp. 4837-4848
-
-
Stenmark, H.1
-
150
-
-
77955393793
-
Regulation of autophagy by transforming growth factor-beta (TGFbeta) signaling
-
Suzuki HI, Kiyono K, Miyazono K. (2010). Regulation of autophagy by transforming growth factor-beta (TGFbeta) signaling. Autophagy 6: 645-647.
-
(2010)
Autophagy
, vol.6
, pp. 645-647
-
-
Suzuki, H.I.1
Kiyono, K.2
Miyazono, K.3
-
151
-
-
0030058723
-
A 400 kb novel deletion unit centromeric to the BRCA1 gene in sporadic epithelial ovarian cancer
-
Tangir J, Muto MG, Berkowitz RS, Welch WR, Bell DA, Mok SC. (1996). A 400 kb novel deletion unit centromeric to the BRCA1 gene in sporadic epithelial ovarian cancer. Oncogene 12: 735-740. (Pubitemid 26072260)
-
(1996)
Oncogene
, vol.12
, Issue.4
, pp. 735-740
-
-
Tangir, J.1
Muto, M.G.2
Berkowitz, R.S.3
Welch, W.R.4
Bell, D.A.5
Mok, S.C.6
-
152
-
-
44649141966
-
Regulation of autophagy by cytoplasmic p53
-
DOI 10.1038/ncb1730, PII NCB1730
-
Tasdemir E, Maiuri MC, Galluzzi L, Vitale I, Djavaheri-Mergny M, D'Amelio M et al. (2008). Regulation of autophagy by cytoplasmic p53. Nat Cell Biol 10: 676-687. (Pubitemid 351772933)
-
(2008)
Nature Cell Biology
, vol.10
, Issue.6
, pp. 676-687
-
-
Tasdemir, E.1
Maiuri, M.C.2
Galluzzi, L.3
Vitale, I.4
Djavaheri-Mergny, M.5
D'Amelio, M.6
Criollo, A.7
Morselli, E.8
Zhu, C.9
Harper, F.10
Nannmark, U.11
Samara, C.12
Pinton, P.13
Vicencio, J.M.14
Carnuccio, R.15
Moll, U.M.16
Madeo, F.17
Paterlini-Brechot, P.18
Rizzuto, R.19
Szabadkai, G.20
Pierron, G.21
Blomgren, K.22
Tavernarakis, N.23
Codogno, P.24
Cecconi, F.25
Kroemer, G.26
more..
-
153
-
-
67651152483
-
Targeted activation of innate immunity for therapeutic induction of autophagy and apoptosis in melanoma cells
-
Tormo D, Checinska A, Alonso-Curbelo D, Perez-Guijarro E, Canon E, Riveiro-Falkenbach E et al. (2009). Targeted activation of innate immunity for therapeutic induction of autophagy and apoptosis in melanoma cells. Cancer Cell 16: 103-114.
-
(2009)
Cancer Cell
, vol.16
, pp. 103-114
-
-
Tormo, D.1
Checinska, A.2
Alonso-Curbelo, D.3
Perez-Guijarro, E.4
Canon, E.5
Riveiro-Falkenbach, E.6
-
154
-
-
85027927831
-
High-resolution characterization of a hepatocellular carcinoma genome
-
Totoki Y, Tatsuno K, Yamamoto S, Arai Y, Hosoda F, Ishikawa S et al. (2011). High-resolution characterization of a hepatocellular carcinoma genome. Nat Genet 43: 464-469.
-
(2011)
Nat Genet
, vol.43
, pp. 464-469
-
-
Totoki, Y.1
Tatsuno, K.2
Yamamoto, S.3
Arai, Y.4
Hosoda, F.5
Ishikawa, S.6
-
155
-
-
45849147350
-
A Molecule Targeting VHL-Deficient Renal Cell Carcinoma that Induces Autophagy
-
DOI 10.1016/j.ccr.2008.06.004, PII S1535610808001943
-
Turcotte S, Chan DA, Sutphin PD, Hay MP, Denny WA, Giaccia AJ. (2008). A molecule targeting VHL-deficient renal cell carcinoma that induces autophagy.
-
(2008)
Cancer Cell
, vol.14
, Issue.1
, pp. 90-102
-
-
Turcotte, S.1
Chan, D.A.2
Sutphin, P.D.3
Hay, M.P.4
Denny, W.A.5
Giaccia, A.J.6
-
156
-
-
48249125798
-
Loss of Pten, a tumor suppressor, causes the strong inhibition of autophagy without affecting LC3 lipidation
-
Ueno T, Sato W, Horie Y, Komatsu M, Tanida I, Yoshida M et al. (2008). Loss of Pten, a tumor suppressor, causes the strong inhibition of autophagy without affecting LC3 lipidation. Autophagy 4: 692-700.
-
(2008)
Autophagy
, vol.4
, pp. 692-700
-
-
Ueno, T.1
Sato, W.2
Horie, Y.3
Komatsu, M.4
Tanida, I.5
Yoshida, M.6
-
157
-
-
77955432889
-
The pan-Bcl-2 inhibitor-gossypol triggers autophagic cell death in malignant glioma
-
Voss V, Senft C, Lang V, Ronellenfitsch MW, Steinbach JP, Seifert V et al. (2010). The pan-Bcl-2 inhibitor-gossypol triggers autophagic cell death in malignant glioma. Mol Cancer Res 8: 1002-1016.
-
(2010)
Mol Cancer Res
, vol.8
, pp. 1002-1016
-
-
Voss, V.1
Senft, C.2
Lang, V.3
Ronellenfitsch, M.W.4
Steinbach, J.P.5
Seifert, V.6
-
158
-
-
77953708091
-
Elevated Beclin 1 expression is correlated with HIF-1alpha in predicting poor prognosis of nasopharyngeal carcinoma
-
Wan XB, Fan XJ, Chen MY, Xiang J, Huang PY, Guo L et al. (2010). Elevated Beclin 1 expression is correlated with HIF-1alpha in predicting poor prognosis of nasopharyngeal carcinoma. Autophagy 6: 395-404.
-
(2010)
Autophagy
, vol.6
, pp. 395-404
-
-
Wan, X.B.1
Fan, X.J.2
Chen, M.Y.3
Xiang, J.4
Huang, P.Y.5
Guo, L.6
-
159
-
-
69249153394
-
A non-canonical MEK/ERK signaling pathway regulates autophagy via regulating Beclin 1
-
Wang J, Whiteman MW, Lian H, Wang G, Singh A, Huang D et al. (2009). A non-canonical MEK/ERK signaling pathway regulates autophagy via regulating Beclin 1. J Biol Chem 284: 21412-21424.
-
(2009)
J Biol Chem
, vol.284
, pp. 21412-21424
-
-
Wang, J.1
Whiteman, M.W.2
Lian, H.3
Wang, G.4
Singh, A.5
Huang, D.6
-
160
-
-
75949104449
-
Mitochondria get a Parkin' ticket
-
Wild P, Dikic I. (2010). Mitochondria get a Parkin' ticket. Nat Cell Biol 12: 104-106.
-
(2010)
Nat Cell Biol
, vol.12
, pp. 104-106
-
-
Wild, P.1
Dikic, I.2
-
161
-
-
77952420148
-
Proteasome inhibition: A new therapeutic strategy to cancer treatment
-
Wu WK, Cho CH, Lee CW, Wu K, Fan D, Yu J et al. (2010a). Proteasome inhibition: a new therapeutic strategy to cancer treatment. Cancer Lett 293: 15-22.
-
(2010)
Cancer Lett
, vol.293
, pp. 15-22
-
-
Wu, W.K.1
Cho, C.H.2
Lee, C.W.3
Wu, K.4
Fan, D.5
Yu, J.6
-
162
-
-
77953230805
-
Macroautophagy and ERK phosphorylation counteract the antiproliferative effect of proteasome inhibitor in gastric cancer cells
-
Wu WK, Cho CH, Lee CW, Wu YC, Yu L, Li ZJ et al. (2010c). Macroautophagy and ERK phosphorylation counteract the antiproliferative effect of proteasome inhibitor in gastric cancer cells. Autophagy 6: 228-238.
-
(2010)
Autophagy
, vol.6
, pp. 228-238
-
-
Wu, W.K.1
Cho, C.H.2
Lee, C.W.3
Wu, Y.C.4
Yu, L.5
Li, Z.J.6
-
163
-
-
77953229918
-
Macroautophagy modulates cellular response to proteasome inhibitors in cancer therapy
-
Wu WK, Sakamoto KM, Milani M, Aldana-Masankgay G, Fan D, Wu K et al. (2010b). Macroautophagy modulates cellular response to proteasome inhibitors in cancer therapy. Drug Resist Updat 13: 87-92.
-
(2010)
Drug Resist Updat
, vol.13
, pp. 87-92
-
-
Wu, W.K.1
Sakamoto, K.M.2
Milani, M.3
Aldana-Masankgay, G.4
Fan, D.5
Wu, K.6
-
164
-
-
77957357004
-
Activated mammalian target of rapamycin is a potential therapeutic target in gastric cancer
-
Xu DZ, Geng QR, Tian Y, Cai MY, Fang XJ, Zhan YQ et al. (2010). Activated mammalian target of rapamycin is a potential therapeutic target in gastric cancer. BMC Cancer 10: 536.
-
(2010)
BMC Cancer
, vol.10
, pp. 536
-
-
Xu, D.Z.1
Geng, Q.R.2
Tian, Y.3
Cai, M.Y.4
Fang, X.J.5
Zhan, Y.Q.6
-
165
-
-
76249095217
-
PERK-dependent regulation of ceramide synthase 6 and thioredoxin play a key role in mda-7/IL-24-induced killing of primary human glioblastoma multiforme cells
-
Yacoub A, Hamed HA, Allegood J, Mitchell C, Spiegel S, Lesniak MS et al. (2010). PERK-dependent regulation of ceramide synthase 6 and thioredoxin play a key role in mda-7/IL-24-induced killing of primary human glioblastoma multiforme cells. Cancer Res 70: 1120-1129.
-
(2010)
Cancer Res
, vol.70
, pp. 1120-1129
-
-
Yacoub, A.1
Hamed, H.A.2
Allegood, J.3
Mitchell, C.4
Spiegel, S.5
Lesniak, M.S.6
-
166
-
-
77957367974
-
Inhibition of autophagy enhances anticancer effects of atorvastatin in digestive malignancies
-
Yang PM, Liu YL, Lin YC, Shun CT, Wu MS, Chen CC. (2010). Inhibition of autophagy enhances anticancer effects of atorvastatin in digestive malignancies. Cancer Res 70: 7699-7709.
-
(2010)
Cancer Res
, vol.70
, pp. 7699-7709
-
-
Yang, P.M.1
Liu, Y.L.2
Lin, Y.C.3
Shun, C.T.4
Wu, M.S.5
Chen, C.C.6
-
167
-
-
79952229430
-
Pancreatic cancers require autophagy for tumor growth
-
Yang S, Wang X, Contino G, Liesa M, Sahin E, Ying H et al. (2011). Pancreatic cancers require autophagy for tumor growth. Genes Dev 25: 717-729.
-
(2011)
Genes Dev
, vol.25
, pp. 717-729
-
-
Yang, S.1
Wang, X.2
Contino, G.3
Liesa, M.4
Sahin, E.5
Ying, H.6
-
168
-
-
77951214016
-
Mammalian autophagy: Core molecular machinery and signaling regulation
-
Yang Z, Klionsky DJ. (2010). Mammalian autophagy: core molecular machinery and signaling regulation. Curr Opin Cell Biol 22: 124-131.
-
(2010)
Curr Opin Cell Biol
, vol.22
, pp. 124-131
-
-
Yang, Z.1
Klionsky, D.J.2
-
169
-
-
33846334501
-
Oncogene-Induced Senescence Pathways Weave an Intricate Tapestry
-
DOI 10.1016/j.cell.2007.01.005, PII S0092867407000578
-
Yaswen P, Campisi J. (2007). Oncogene-induced senescence pathways weave an intricate tapestry. Cell 128: 233-234. (Pubitemid 46123519)
-
(2007)
Cell
, vol.128
, Issue.2
, pp. 233-234
-
-
Yaswen, P.1
Campisi, J.2
-
170
-
-
67650745428
-
PUMA-and Bax-induced autophagy contributes to apoptosis
-
Yee KS, Wilkinson S, James J, Ryan KM, Vousden KH. (2009). PUMA-and Bax-induced autophagy contributes to apoptosis. Cell Death Differ 16: 1135-1145.
-
(2009)
Cell Death Differ
, vol.16
, pp. 1135-1145
-
-
Yee, K.S.1
Wilkinson, S.2
James, J.3
Ryan, K.M.4
Vousden, K.H.5
-
171
-
-
54849188100
-
LC3, an autophagosome marker, is highly expressed in gastrointestinal cancers
-
Yoshioka A, Miyata H, Doki Y, Yamasaki M, Sohma I, Gotoh K et al. (2008). LC3, an autophagosome marker, is highly expressed in gastrointestinal cancers. Int J Oncol 33: 461-468.
-
(2008)
Int J Oncol
, vol.33
, pp. 461-468
-
-
Yoshioka, A.1
Miyata, H.2
Doki, Y.3
Yamasaki, M.4
Sohma, I.5
Gotoh, K.6
-
172
-
-
64349123107
-
Autophagy mediates the mitotic senescence transition
-
Young AR, Narita M, Ferreira M, Kirschner K, Sadaie M, Darot JF et al. (2009). Autophagy mediates the mitotic senescence transition. Genes Dev 23: 798-803.
-
(2009)
Genes Dev
, vol.23
, pp. 798-803
-
-
Young, A.R.1
Narita, M.2
Ferreira, M.3
Kirschner, K.4
Sadaie, M.5
Darot, J.F.6
-
173
-
-
33749162486
-
Calpain-mediated cleavage of Atg5 switches autophagy to apoptosis
-
DOI 10.1038/ncb1482, PII NCB1482
-
Yousefi S, Perozzo R, Schmid I, Ziemiecki A, Schaffner T, Scapozza L et al. (2006). Calpain-mediated cleavage of Atg5 switches autophagy to apoptosis. Nat Cell Biol 8: 1124-1132. (Pubitemid 44473608)
-
(2006)
Nature Cell Biology
, vol.8
, Issue.10
, pp. 1124-1132
-
-
Yousefi, S.1
Perozzo, R.2
Schmid, I.3
Ziemiecki, A.4
Schaffner, T.5
Scapozza, L.6
Brunner, T.7
Simon, H.-U.8
-
174
-
-
0345166111
-
Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor
-
DOI 10.1073/pnas.2436255100
-
Yue Z, Jin S, Yang C, Levine AJ, Heintz N. (2003). Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor. Proc Natl Acad Sci USA 100: 15077-15082. (Pubitemid 37518019)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.25
, pp. 15077-15082
-
-
Yue, Z.1
Jin, S.2
Yang, C.3
Levine, A.J.4
Heintz, N.5
-
175
-
-
42049095495
-
Mammalian target of rapamycin and S6 kinase 1 positively regulate 6-thioguanine-induced autophagy
-
DOI 10.1158/0008-5472.CAN-07-6163
-
Zeng X, Kinsella TJ. (2008). Mammalian target of rapamycin and S6 kinase 1 positively regulate 6-thioguanine-induced autophagy. Cancer Res 68: 2384-2390. (Pubitemid 351521813)
-
(2008)
Cancer Research
, vol.68
, Issue.7
, pp. 2384-2390
-
-
Zeng, X.1
Kinsella, T.J.2
-
176
-
-
37649024076
-
Small molecule regulators of autophagy identified by an image-based highthroughput screen
-
Zhang L, Yu J, Pan H, Hu P, Hao Y, Cai W et al. (2007). Small molecule regulators of autophagy identified by an image-based highthroughput screen. Proc Natl Acad Sci USA 104: 19023-19028.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 19023-19028
-
-
Zhang, L.1
Yu, J.2
Pan, H.3
Hu, P.4
Hao, Y.5
Cai, W.6
-
177
-
-
68949198785
-
MTOR signaling pathway is a target for the treatment of colorectal cancer
-
Zhang YJ, Dai Q, Sun DF, Xiong H, Tian XQ, Gao FH et al. (2009b). mTOR signaling pathway is a target for the treatment of colorectal cancer. Ann Surg Oncol 16: 2617-2628.
-
(2009)
Ann Surg Oncol
, vol.16
, pp. 2617-2628
-
-
Zhang, Y.J.1
Dai, Q.2
Sun, D.F.3
Xiong, H.4
Tian, X.Q.5
Gao, F.H.6
-
178
-
-
77149172547
-
Expression of Beclin1 in osteosarcoma and the effects of down-regulation of autophagy on the chemotherapeutic sensitivity
-
Zhang Z, Shao Z, Xiong L, Che B, Deng C, Xu W. (2009a). Expression of Beclin1 in osteosarcoma and the effects of down-regulation of autophagy on the chemotherapeutic sensitivity. J Huazhong Univ Sci Technolog Med Sci 29: 737-740.
-
(2009)
J Huazhong Univ Sci Technolog Med Sci
, vol.29
, pp. 737-740
-
-
Zhang, Z.1
Shao, Z.2
Xiong, L.3
Che, B.4
Deng, C.5
Xu, W.6
-
179
-
-
77954225200
-
Cytosolic FoxO1 is essential for the induction of autophagy and tumour suppressor activity
-
Zhao Y, Yang J, Liao W, Liu X, Zhang H, Wang S et al. (2010). Cytosolic FoxO1 is essential for the induction of autophagy and tumour suppressor activity. Nat Cell Biol 12: 665-675.
-
(2010)
Nat Cell Biol
, vol.12
, pp. 665-675
-
-
Zhao, Y.1
Yang, J.2
Liao, W.3
Liu, X.4
Zhang, H.5
Wang, S.6
-
180
-
-
78751655392
-
Bcl-2 and Bcl-xL play important roles in the crosstalk between autophagy and apoptosis
-
Zhou F, Yang Y, Xing D. (2011). Bcl-2 and Bcl-xL play important roles in the crosstalk between autophagy and apoptosis. FEBS J 278: 403-413.
-
(2011)
FEBS J
, vol.278
, pp. 403-413
-
-
Zhou, F.1
Yang, Y.2
Xing, D.3
|