Relative down-regulation of apoptosis and autophagy genes in colorectal cancer

European Journal of Clinical Investigation

Volumn 41, Issue 1, 2011, Pages 84-92

  Chang, Ying Tse ^a   Tseng, Hsien Chun ^b,c   Huang, Chi Chou ^c   Chen, Ya Pei ^b   Chiang, Huei Ching ^c   Chou, Fen Pi ^b,c  

^a TUNGS' TAICHUNG METROHARBOR HOSPITAL   (Taiwan)

^b CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^c CHUNG SHAN MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

Gene expression; Programmed cell death; RT qPCR

Indexed keywords

APOPTOTIC PROTEASE ACTIVATING FACTOR 1; AUTOPHAGY PROTEIN 5; CASPASE 3; CASPASE 8; CASPASE 9; FAS ANTIGEN; FAS ASSOCIATED DEATH DOMAIN PROTEIN; FAS LIGAND; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; MESSENGER RNA; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN KINASE B; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR RECEPTOR; X LINKED INHIBITOR OF APOPTOSIS;

AKT1 GENE; APOPTOSIS; ARTICLE; ATG7 GENE; AUTOPHAGY; BCL2L1 GENE; CANCER TISSUE; COLORECTAL CANCER; CONTROLLED STUDY; DOWN REGULATION; DRAM GENE; GENE; GENE EXPRESSION; HUMAN; HUMAN TISSUE; MAP1LC3 GENE; PATHOPHYSIOLOGY; PRIORITY JOURNAL;

ADENOCARCINOMA; APOPTOSIS; AUTOPHAGY; COLORECTAL NEOPLASMS; DOWN-REGULATION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; RNA, MESSENGER;

EID: 78650041248     PISSN: 00142972     EISSN: 13652362     Source Type: Journal    
DOI: 10.1111/j.1365-2362.2010.02383.x     Document Type: Article

References (31)

1. Eisenberg-Lerner A, Bialik S, Simon HU, Kimchi A. Life and death partners: apoptosis, autophagy and thecross-talk between them. Cell Death Differ 2009;16:1-10.
2. Twomey C, McCarthy JV. Pathways of apoptosis and importance in development. J Cell Mol Med 2005;9:345-59.
3. Scorrano L, Korsmeyer SJ. Mechanisms of cytochrome c release by proapoptotic BCL-2 family members. Biochem Biophys Res Commun 2003;304:437-44.
4. Degterev A, Boyce M, Yuan J. A decade of caspases. Oncogene 2003;22:8543-67.
5. Igney FH, Krammer PH. Death and anti-death: tumour resistance to apoptosis. Nat Rev Cancer 2002;2:277-88.
6. Bursch W, Hochegger K, Torok L, Marian B, Ellinger A, Hermann RS. Autophagic and apoptotic types of programmed cell death exhibit different fates of cytoskeletal filaments. J Cell Sci 2000;113:1189-98.
7. Kelekar A. Autophagy Ann N Y Acad Sci 2005;1066:259-71.
8. Klionsky DJ, Cregg JM, Dunn WA Jr, Emr SD, Sakai Y, Sandoval IV et al. A unified nomenclature for yeast autophagy-related genes. Dev Cell 2003;5:539-45.
9. Tsukada M, Ohsumi Y. Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae. FEBS Lett 1993;333:169-74.
10. Tanida I, Ueno T, Kominami E. LC3 conjugation system in mammalian autophagy. Int J Biochem Cell Biol 2004;36:2503-18.
11. Klionsky DJ, Cuervo AM, Seglen PO. Methods for monitoring autophagy from yeast to human. Autophagy 2007;3:181-206.
12. Kabeya Y, Mizushima N, Ueno T, Yamamoto A, Kirisako T, Noda T et al. LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing. EMBO J 2000;19:5720-8.
13. Mizushima N, Yamamoto A, Matsui M, Yoshimori T, Ohsumi Y. In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker. Mol Biol Cell 2004;15:1101-11.
14. Meijer AJ, Codogno P. Regulation and role of autophagy in mammalian cells. Int J Biochem Cell Biol 2004;36:2445-62.
15. Petiot A, Ogier-Denis E, Blommaart EF, Meijer AJ, Codogno P. Distinct classes of phosphatidylinositol 3'-kinases are involved in signaling pathways that control macroautophagy in HT-29 cells. J Biol Chem 2000;275:992-8.
16. Elmore SP, Qian T, Grissom SF, Lemasters JJ. The mitochondrial permeability transition initiates autophagy in rat hepatocytes. FASEB J 2001;15:2286-7.
17. Li J, Hou N, Faried A, Tsutsumi S, Kuwano H. Inhibition of autophagy augments 5-fluorouracil chemotherapy in human colon cancer in vitro and in vivo model. Eur J Cancer 2010;46:1900-9.
18. Giannopoulou E, Antonacopoulou A, Matsouka P, Kalofonos HP. Autophagy: novel action of panitumumab in colon cancer. Anticancer Res 2009;29:5077-82.
19. King A, Gottlieb E. Glucose metabolism and programmed cell death: an evolutionary and mechanistic perspective. Curr Opin Cell Biol 2009;21:885-93.
20. Scarlatti F, Bauvy C, Ventruti A, Sala G, Cluzeaud F, Vandewalle A et al. Ceramide-mediated macroautophagy involves inhibition of protein kinase B and up-regulation of beclin 1. J Biol Chem 2004;279:18384-91.
21. Kanzawa T, Germano IM, Komata T, Ito H, Kondo Y, Kondo S. Role of autophagy in temozolomide-induced cytotoxicity for malignant glioma cells. Cell Death Differ 2004;11:448-57.
22. Hector S, Prehn JHM. Apoptosis signaling proteins as prognostic biomarkers in colorectal cancer: a review. Biochimica Biophysica Acta 2009;1795:117-29.
23. Li BX, Li CY, Peng RQ, Wu XJ, Wang HY, Wan DS et al. The expression of beclin 1 is associated with favorable prognosis in stage IIIB colon cancers. Autophagy 2009;5:303-6.
24. Coppola D, Khalil F, Eschrich SA, Boulware D, Yeatman T, Wang HG. Down-regulation of Bax-interacting factor-1 in colorectal adenocarcinoma. Cancer 2008;113:2665-70.
25. Ahn CH, Jeong EG, Lee JW, Kim MS, Kim SH, Kim SS et al. Expression of beclin-1, an autophagy-related protein, in gastric and colorectal cancers. APMIS 2007;115:1344-9.
26. Tennant DA, Duran RV, Boulahbel H, Gottlieb E. Metabolic transformation in cancer. Carcinogenesis 2009;30:1269-80.
27. Lee IT, Lin CC, Wu YC, Yang CM. TNF-alpha induces matrix metalloproteinase-9 expression in A549 cells: role of TNFR1/TRAF2/PKCalpha-dependent signaling pathways. J Cell Physiol 2010;224:454-64.
28. Takei Y, Laskey R. Tumor necrosis factor alpha regulates responses to nerve growth factor, promoting neural cell survival but suppressing differentiation of neuroblastoma cells. Mol Biol Cell 2008;19:855-64.
29. Rivas MA, Carnevale RP, Proietti CJ, Rosemblit C, Beguelin W, Salatino M et al. TNF alpha acting on TNFR1 promotes breast cancer growth via p42/P44 MAPK, JNK, Akt and NF-kappa B-dependent pathways. Exp Cell Res 2008;314:509-29.
30. Huber HJ, Rehm M, Plchut M, Dussmann H, Prehn JH. APOPTO-CELL-a simulation tool and interactive database for analyzing cellular susceptibility to apoptosis. Bioinformatics 2007;23:648-50.
31. Rehm M, Huber HJ, Dussmann H, Prehn JH. Systems analysis of effector caspase activation and its control by X-linked inhibitor of apoptosis protein. EMBO J 2006;25:4338-49.