Cation trapping by cellular acidic compartments: Beyond the concept of lysosomotropic drugs

Toxicology and Applied Pharmacology

Volumn 259, Issue 1, 2012, Pages 1-12

  Marceau, François ^a   Bawolak, Marie Thérèse ^a   Lodge, Robert ^b   Bouthillier, Johanne ^a   Gagné Henley, Angélique ^a   C Gaudreault, René ^a   Morissette, Guillaume ^a  

^a LAVAL UNIVERSITY   (Canada)

^b LAVAL UNIVERSITY   (Canada)

Author keywords

Autophagy; Cell vacuolization; Ion trapping; Lysosomotropic drugs; Phospholipidosis; Vacuolar ATPase

Indexed keywords

ADENOSINE TRIPHOSPHATASE; AMINE; BAFILOMYCIN A1; CATION;

CELL COMPARTMENTALIZATION; CELL LABELING; CELL ORGANELLE; CELL VACUOLE; DRUG DISTRIBUTION; ENDOCYTOSIS; ENDOSOME; GOLGI COMPLEX; HUMAN; LIPOPHILICITY; LYSOSOME; MACROAUTOPHAGY; NONHUMAN; PHYSICAL CHEMISTRY; PROTEIN SECRETION; REVIEW; SIGNAL TRANSDUCTION;

ANIMALS; AUTOPHAGY; BIOLOGICAL TRANSPORT; CATIONS; ENDOCYTOSIS; HUMANS; LYSOSOMES; MITOSIS; MYOCYTES, SMOOTH MUSCLE; PHARMACEUTICAL PREPARATIONS; VACUOLAR PROTON-TRANSLOCATING ATPASES; VACUOLES;

EID: 84857111835     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2011.12.004     Document Type: Review

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