Tamoxifen inhibits acidification in cells independent of the estrogen receptor

Proceedings of the National Academy of Sciences of the United States of America

Volumn 96, Issue 8, 1999, Pages 4432-4437

  Altan, Nihal ^a,c   Chen, Yu ^a   Schindler, Melvin ^b   Simon, Sanford M ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

^b Michigan State University   (United States)

^c EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

Author keywords

Bone resorption; Breast cancer; Muitidrug resistance; PH

Indexed keywords

BAFILOMYCIN A1; DAUNORUBICIN; DOXORUBICIN; ESTROGEN RECEPTOR; MITOXANTRONE; MONENSIN; TAMOXIFEN;

ACIDIFICATION; ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER; CELL FUNCTION; CELL PH; DRUG EFFECT; DRUG MECHANISM; DRUG SENSITIZATION; ENDOSOME; HUMAN; HUMAN CELL; LYSOSOME; PRIORITY JOURNAL; TUMOR CELL;

ANTI-BACTERIAL AGENTS; BIOLOGICAL TRANSPORT; BORON COMPOUNDS; BREAST NEOPLASMS; CYTOPLASM; DOXORUBICIN; DRUG RESISTANCE, NEOPLASM; ENDOSOMES; FEMALE; FLUORESCENT DYES; HUMANS; HYDROGEN-ION CONCENTRATION; LYSOSOMES; MACROLIDES; MONENSIN; NEUROBLASTOMA; RECEPTORS, ESTROGEN; TAMOXIFEN; TRANSFERRIN; TUMOR CELLS, CULTURED;

EID: 0033551150     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.96.8.4432     Document Type: Article

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