Receptor-independent, vacuolar ATPase-mediated cellular uptake of histamine receptor-1 ligands: Possible origin of pharmacological distortions and side effects

Toxicology and Applied Pharmacology

Volumn 229, Issue 3, 2008, Pages 320-331

  Morissette, Guillaume ^a,b   Lodge, Robert ^c   Bouthillier, Johanne ^a,b   Marceau, François ^a,b  

^a LAVAL UNIVERSITY   (Canada)

^b UNIVERSITÉ LAVAL   (Canada)

^c LAVAL UNIVERSITY   (Canada)

Author keywords

Astemizole; Autophagy; Bafilomycin A1; Betahistine; Histamine; Smooth muscle cells; Terfenadine; V ATPase

Indexed keywords

ADENOSINE TRIPHOSPHATASE; ASTEMIZOLE; BAFILOMYCIN A1; BETAHISTINE; CD63 ANTIGEN; DIPHENHYDRAMINE; HISTAMINE H1 RECEPTOR AGONIST; HISTAMINE H1 RECEPTOR ANTAGONIST; MEPYRAMINE; RAB7 PROTEIN; TELE METHYLHISTAMINE; TERFENADINE;

ACIDITY; ANIMAL CELL; AORTA; AORTA CONSTRICTION; ARTICLE; AUTOPHAGY; CELL ORGANELLE; CELL STRUCTURE; CELL VACUOLE; CONTROLLED STUDY; CYTOPATHOLOGY; FLUORESCENCE; LIPOPHILICITY; NONHUMAN; TONOPLAST; VASCULAR SMOOTH MUSCLE;

ANIMALS; AORTA; AUTOPHAGY; BIOLOGICAL TRANSPORT; DOSE-RESPONSE RELATIONSHIP, DRUG; HISTAMINE AGONISTS; HISTAMINE H1 ANTAGONISTS; HYDROPHOBICITY; LIGANDS; MACROLIDES; MUSCLE CONTRACTION; RABBITS; RECEPTORS, HISTAMINE H1; VACUOLAR PROTON-TRANSLOCATING ATPASES; VACUOLES;

ORYCTOLAGUS CUNICULUS;

EID: 44349133221     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2008.01.028     Document Type: Article

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