Comparison of preservative-free bupivacaine vs lidocaine for intracameral anesthesia: A randomized clinical trial and in vitro analysis

American Journal of Ophthalmology

Volumn 127, Issue 4, 1999, Pages 393-402

  Anderson, Nicole J ^a   Nath, Rajiv ^b   Anderson, C Joseph ^b   Edelhauser, Henry F ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BUPIVACAINE; LIDOCAINE;

ADULT; AGED; ARTICLE; CATARACT EXTRACTION; CELL STRUCTURE; CELL VIABILITY; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORNEA EDEMA; CORNEA INJURY; CYTOTOXICITY; DILUTION; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG MANUFACTURE; DRUG SOLUBILITY; FEMALE; HUMAN; LENS IMPLANTATION; LIPID SOLUBILITY; MALE; NONHUMAN; OUTCOMES RESEARCH; PERIOCULAR DRUG ADMINISTRATION; PHACOEMULSIFICATION; PRIORITY JOURNAL; RABBIT; RANDOMIZED CONTROLLED TRIAL;

EID: 0033118855     PISSN: 00029394     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9394(98)00417-6     Document Type: Article

References (20)

1. Hamilton R.C., Grizzard W.S. Complications. Gills J.P., Hustead R.F., Sanders D.R. Ophthalmic anesthesia. 1993;187-202 Slack, Thorofare, New Jersey.
2. Smith R. Cataract extraction without retrobulbar anesthetic injection. Br J Ophthalmol. 74:1990;205-207.
3. Redmond R.M., Dallas N.L. Extracapsular cataract extraction under local anesthesia without retrobulbar injection. Br J Ophthalmol. 74:1990;203-204.
4. Peterson W.C., Yanoff M. Why retrobulbar anesthesia? Trans Am Ophthalmol Soc. 88:1990;136-147.
5. Anderson C.J. Subconjunctival anesthesia in cataract surgery. J Cataract Refract Surg. 21:1995;103-105.
6. Kershner R.M. Topical anesthesia for small incision self sealing cataract surgery a prospective evaluation of the first 100 patients . J Cataract Refract Surg. 19:1993;290-292.
7. Anderson C.J. Combined topical and subconjunctival anesthesia in cataract surgery. Ophthalmic Surg. 26:1995;205-208.
8. Anderson C.J. Circumferential perilimbal anesthesia. J Cataract Refract Surg. 22:1996;1009-1012.
9. Gills J.P., Cherchio M., Raanan M.G. Unpreserved lidocaine to control discomfort during cataract surgery using topical anesthesia. J Cataract Refract Surg. 23:1997;545-550.
10. Koch P.S. Anterior chamber irrigation with unpreserved lidocaine 1% for anesthesia during cataract surgery. J Cataract Refract Surg. 23:1997;551-554.
11. Kim T., Holley G.P., Jong H.L., Broocker G., Edelhauser H.F. The effects of intraocular lidocaine on the corneal endothelium. Ophthalmology. 105:1998;125-130.
12. McCarey B.E., Edelhauser H.F., Van Horn D.L. Functional and structural changes in the corneal endothelium during in vitro perfusion. Invest Ophthalmol Vis Sci. 12:1973;410-417.
13. Dikstein S., Maurice D.M. The metabolic basis to the fluid pump in the cornea. J Physiol. 221:1972;29-41.
14. Means T.L., Geroski D.H., Hadley A., Lynn M.J., Edelhauser H.F. Viability of human corneal endothelium following Optisol-GS storage. Arch Ophthalmol. 113:1995;805-809.
15. Gonnering R., Edelhauser H.F., Van Horn D.L., Durant W. The pH tolerance of rabbit and human corneal endothelium. Invest Ophthalmol Vis Sci. 18:1979;374-388.
16. Anderson NJ, Kim T, Woods WD, Rudnick DE, Edelhauser HF. Intracameral anesthesia: in vitro iris and corneal uptake and washout of lidocaine HCl 1%. Arch Ophthalmol. Forthcoming.
17. Smith R.B., Everett W.G. Physiology and pharmacology of local anesthetic agents. J Ocular Toxicology. 58:1986;35-59.
18. Covino B.G. Pharmacology of local anaesthetic agents. Br J Anaesth. 58:1986;701-716.
19. Tucker G.T. Pharmacokinetics of local anaesthetics. Br J Anaesth. 58:1986;717-731.
20. Judge A.J., Katayoun N., Lee D., Miller K. Corneal endothelial toxicity of topical anesthetics. Ophthalmology. 104:1997;1373-1379.