5α-Reduced glucocorticoids: A story of natural selection

Journal of Endocrinology

Volumn 212, Issue 2, 2012, Pages 111-127

  Nixon, Mark ^a   Upreti, Rita ^a   Andrew, Ruth ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFLAMMATORY AGENT; BIOLOGICAL MARKER; GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; STEROID; STEROID 5ALPHA REDUCTASE 1; STEROID 5ALPHA REDUCTASE 2; STEROID 5ALPHA REDUCTASE INHIBITOR; STEROID 5BETA REDUCTASE; TRANSCRIPTION FACTOR AP 1; TUMOR NECROSIS FACTOR ALPHA;

BIOSYNTHESIS; DNA BINDING; GENE EXPRESSION; GENETIC TRANSCRIPTION; GENETIC VARIABILITY; HUMAN; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; METABOLIC DISORDER; METABOLITE; NATURAL SELECTION; NONHUMAN; PRIORITY JOURNAL; RECEPTOR BINDING; RECEPTOR UPREGULATION; REVIEW; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION;

3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE; 5-ALPHA REDUCTASE INHIBITORS; ANIMALS; ANTI-INFLAMMATORY AGENTS; BIOLOGICAL MARKERS; CORTICOSTERONE; GLUCOCORTICOIDS; HUMANS; HYDROCORTISONE; INFLAMMATION; ISOENZYMES; LIVER; RECEPTORS, GLUCOCORTICOID; SELECTION, GENETIC; SIGNAL TRANSDUCTION;

EID: 84856973203     PISSN: 00220795     EISSN: 14796805     Source Type: Journal    
DOI: 10.1530/JOE-11-0318     Document Type: Review

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