-
1
-
-
0030941803
-
The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor
-
Brown M.S., and Goldstein J.L. The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor. Cell 89 (1997) 331-340
-
(1997)
Cell
, vol.89
, pp. 331-340
-
-
Brown, M.S.1
Goldstein, J.L.2
-
2
-
-
0033613147
-
A proteolytic pathway that controls the cholesterol content of membranes, cells, and blood
-
Brown M.S., and Goldstein J.L. A proteolytic pathway that controls the cholesterol content of membranes, cells, and blood. Proc. Natl. Acad. Sci. U. S. A. 96 (1999) 11041-11048
-
(1999)
Proc. Natl. Acad. Sci. U. S. A.
, vol.96
, pp. 11041-11048
-
-
Brown, M.S.1
Goldstein, J.L.2
-
3
-
-
4444349833
-
Selective coactivator interactions in gene activation by SREBP-1a and -1c
-
Toth J.I., Datta S., Athanikar J.N., Freedman L.P., and Osborne T.F. Selective coactivator interactions in gene activation by SREBP-1a and -1c. Mol. Cell. Biol. 24 (2004) 8288-8300
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 8288-8300
-
-
Toth, J.I.1
Datta, S.2
Athanikar, J.N.3
Freedman, L.P.4
Osborne, T.F.5
-
4
-
-
0035830840
-
Unsaturated fatty acids down-regulate srebp isoforms 1a and 1c by two mechanisms in HEK-293 cells
-
Hannah V.C., Ou J., Luong A., Goldstein J.L., and Brown M.S. Unsaturated fatty acids down-regulate srebp isoforms 1a and 1c by two mechanisms in HEK-293 cells. J. Biol. Chem. 276 (2001) 4365-4372
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 4365-4372
-
-
Hannah, V.C.1
Ou, J.2
Luong, A.3
Goldstein, J.L.4
Brown, M.S.5
-
5
-
-
0036680098
-
Hormones and prostate cancer: current perspectives and future directions
-
Hsing A.W., Reichardt J.K., and Stanczyk F.Z. Hormones and prostate cancer: current perspectives and future directions. Prostate 52 (2002) 213-235
-
(2002)
Prostate
, vol.52
, pp. 213-235
-
-
Hsing, A.W.1
Reichardt, J.K.2
Stanczyk, F.Z.3
-
6
-
-
0026055914
-
Deletion of steroid 5 alpha-reductase 2 gene in male pseudohermaphroditism
-
Andersson S., Berman D.M., Jenkins E.P., and Russell D.W. Deletion of steroid 5 alpha-reductase 2 gene in male pseudohermaphroditism. Nature 354 (1991) 159-161
-
(1991)
Nature
, vol.354
, pp. 159-161
-
-
Andersson, S.1
Berman, D.M.2
Jenkins, E.P.3
Russell, D.W.4
-
7
-
-
0028173882
-
Steroid 5 alpha-reductase: two genes/two enzymes
-
Russell D.W., and Wilson J.D. Steroid 5 alpha-reductase: two genes/two enzymes. Annu. Rev. Biochem. 63 (1994) 25-61
-
(1994)
Annu. Rev. Biochem.
, vol.63
, pp. 25-61
-
-
Russell, D.W.1
Wilson, J.D.2
-
8
-
-
0026723090
-
Tissue distribution and kinetic characteristics of rat steroid 5 alpha-reductase isozymes. Evidence for distinct physiological functions
-
Normington K., and Russell D.W. Tissue distribution and kinetic characteristics of rat steroid 5 alpha-reductase isozymes. Evidence for distinct physiological functions. J. Biol. Chem. 267 (1992) 19548-19554
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 19548-19554
-
-
Normington, K.1
Russell, D.W.2
-
9
-
-
0029990372
-
5 alpha-reduced androgens play a key role in murine parturition
-
Mahendroo M.S., Cala K.M., and Russell D.W. 5 alpha-reduced androgens play a key role in murine parturition. Mol. Endocrinol. 10 (1996) 380-392
-
(1996)
Mol. Endocrinol.
, vol.10
, pp. 380-392
-
-
Mahendroo, M.S.1
Cala, K.M.2
Russell, D.W.3
-
11
-
-
0028946134
-
Cloning, expression and functional characterization of type 1 and type 2 steroid 5 alpha-reductases from Cynomolgus monkey: comparisons with human and rat isoenzymes
-
Levy M.A., Brandt M., Sheedy K.M., Holt D.A., Heaslip J.I., Trill J.J., Ryan P.J., Morris R.A., Garrison L.M., and Bergsma D.J. Cloning, expression and functional characterization of type 1 and type 2 steroid 5 alpha-reductases from Cynomolgus monkey: comparisons with human and rat isoenzymes. J. Steroid Biochem. Mol. Biol. 52 (1995) 307-319
-
(1995)
J. Steroid Biochem. Mol. Biol.
, vol.52
, pp. 307-319
-
-
Levy, M.A.1
Brandt, M.2
Sheedy, K.M.3
Holt, D.A.4
Heaslip, J.I.5
Trill, J.J.6
Ryan, P.J.7
Morris, R.A.8
Garrison, L.M.9
Bergsma, D.J.10
-
12
-
-
0032076187
-
5 alpha-reductase isozymes in the central nervous system
-
Poletti A., Coscarella A., Negri-Cesi P., Colciago A., Celotti F., and Martini L. 5 alpha-reductase isozymes in the central nervous system. Steroids 63 (1998) 246-251
-
(1998)
Steroids
, vol.63
, pp. 246-251
-
-
Poletti, A.1
Coscarella, A.2
Negri-Cesi, P.3
Colciago, A.4
Celotti, F.5
Martini, L.6
-
13
-
-
47049092561
-
Selective binding of sterol regulatory element-binding protein isoforms and co-regulatory proteins to promoters for lipid metabolic genes in liver
-
Bennett M.K., Seo Y.K., Datta S., Shin D.J., and Osborne T.F. Selective binding of sterol regulatory element-binding protein isoforms and co-regulatory proteins to promoters for lipid metabolic genes in liver. J. Biol. Chem. 283 (2008) 15628-15637
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 15628-15637
-
-
Bennett, M.K.1
Seo, Y.K.2
Datta, S.3
Shin, D.J.4
Osborne, T.F.5
-
15
-
-
0033812189
-
Effects of high-dose simvastatin on adrenal and gonadal steroidogenesis in men with hypercholesterolemia
-
Dobs A.S., Schrott H., Davidson M.H., Bays H., Stein E.A., Kush D., Wu M., Mitchel Y., and Illingworth R.D. Effects of high-dose simvastatin on adrenal and gonadal steroidogenesis in men with hypercholesterolemia. Metabolism 49 (2000) 1234-1238
-
(2000)
Metabolism
, vol.49
, pp. 1234-1238
-
-
Dobs, A.S.1
Schrott, H.2
Davidson, M.H.3
Bays, H.4
Stein, E.A.5
Kush, D.6
Wu, M.7
Mitchel, Y.8
Illingworth, R.D.9
-
16
-
-
0028088362
-
Short and long-term effects of growth hormone treatment on lipid, lipoprotein, and apolipoprotein levels in short normal children
-
Azzarito C., Boiardi L., Zini M., Agosti A., Biacchessi M., Biagi R., and Portioli I. Short and long-term effects of growth hormone treatment on lipid, lipoprotein, and apolipoprotein levels in short normal children. Horm. Metab. Res. 26 (1994) 432-435
-
(1994)
Horm. Metab. Res.
, vol.26
, pp. 432-435
-
-
Azzarito, C.1
Boiardi, L.2
Zini, M.3
Agosti, A.4
Biacchessi, M.5
Biagi, R.6
Portioli, I.7
-
17
-
-
1042276981
-
Analysis of genome-wide histone acetylation state and enzyme binding using DNA microarrays
-
Robyr D., Kurdistani S.K., and Grunstein M. Analysis of genome-wide histone acetylation state and enzyme binding using DNA microarrays. Methods Enzymol. 376 (2004) 289-304
-
(2004)
Methods Enzymol.
, vol.376
, pp. 289-304
-
-
Robyr, D.1
Kurdistani, S.K.2
Grunstein, M.3
-
18
-
-
33748519257
-
Two uniquely arranged thyroid hormone response elements in the far upstream 5′ flanking region confer direct thyroid hormone regulation to the murine cholesterol 7alpha hydroxylase gene
-
Shin D.J., Plateroti M., Samarut J., and Osborne T.F. Two uniquely arranged thyroid hormone response elements in the far upstream 5′ flanking region confer direct thyroid hormone regulation to the murine cholesterol 7alpha hydroxylase gene. Nucleic Acids Res. 34 (2006) 3853-3861
-
(2006)
Nucleic Acids Res.
, vol.34
, pp. 3853-3861
-
-
Shin, D.J.1
Plateroti, M.2
Samarut, J.3
Osborne, T.F.4
-
19
-
-
0346118926
-
PGC-1alpha activates CYP7A1 and bile acid biosynthesis
-
Shin D.J., Campos J.A., Gil G., and Osborne T.F. PGC-1alpha activates CYP7A1 and bile acid biosynthesis. J. Biol. Chem. 278 (2003) 50047-50052
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 50047-50052
-
-
Shin, D.J.1
Campos, J.A.2
Gil, G.3
Osborne, T.F.4
-
20
-
-
0032568824
-
HLH106, a Drosophila sterol regulatory element-binding protein in a natural cholesterol auxotroph
-
Rosenfeld J.M., and Osborne T.F. HLH106, a Drosophila sterol regulatory element-binding protein in a natural cholesterol auxotroph. J. Biol. Chem. 273 (1998) 16112-16121
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 16112-16121
-
-
Rosenfeld, J.M.1
Osborne, T.F.2
-
21
-
-
55849136194
-
SREBP-2 regulates gut peptide secretion through intestinal bitter taste receptor signaling in mice
-
Jeon T.I., Zhu B., Larson J.L., and Osborne T.F. SREBP-2 regulates gut peptide secretion through intestinal bitter taste receptor signaling in mice. J. Clin. Invest. 118 (2008) 3693-3700
-
(2008)
J. Clin. Invest.
, vol.118
, pp. 3693-3700
-
-
Jeon, T.I.1
Zhu, B.2
Larson, J.L.3
Osborne, T.F.4
-
22
-
-
0030868519
-
Sterol regulation of acetyl coenzyme A carboxylase promoter requires two interdependent binding sites for sterol regulatory element binding proteins
-
Magana M.M., Lin S.S., Dooley K.A., and Osborne T.F. Sterol regulation of acetyl coenzyme A carboxylase promoter requires two interdependent binding sites for sterol regulatory element binding proteins. J. Lipid Res. 38 (1997) 1630-1638
-
(1997)
J. Lipid Res.
, vol.38
, pp. 1630-1638
-
-
Magana, M.M.1
Lin, S.S.2
Dooley, K.A.3
Osborne, T.F.4
-
23
-
-
0027648820
-
ADD1: a novel helix-loop-helix transcription factor associated with adipocyte determination and differentiation
-
Tontonoz P., Kim J.B., Graves R.A., and Spiegelman B.M. ADD1: a novel helix-loop-helix transcription factor associated with adipocyte determination and differentiation. Mol. Cell. Biol. 13 (1993) 4753-4759
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 4753-4759
-
-
Tontonoz, P.1
Kim, J.B.2
Graves, R.A.3
Spiegelman, B.M.4
-
24
-
-
0027490174
-
SREBP-1, a basic-helix-loop-helix-leucine zipper protein that controls transcription of the low density lipoprotein receptor gene
-
Yokoyama C., Wang X., Briggs M.R., Admon A., Wu J., Hua X., Goldstein J.L., and Brown M.S. SREBP-1, a basic-helix-loop-helix-leucine zipper protein that controls transcription of the low density lipoprotein receptor gene. Cell 75 (1993) 187-197
-
(1993)
Cell
, vol.75
, pp. 187-197
-
-
Yokoyama, C.1
Wang, X.2
Briggs, M.R.3
Admon, A.4
Wu, J.5
Hua, X.6
Goldstein, J.L.7
Brown, M.S.8
-
25
-
-
0036251153
-
SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver
-
Horton J.D., Goldstein J.L., and Brown M.S. SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver. J. Clin. Invest. 109 (2002) 1125-1131
-
(2002)
J. Clin. Invest.
, vol.109
, pp. 1125-1131
-
-
Horton, J.D.1
Goldstein, J.L.2
Brown, M.S.3
-
26
-
-
0033612369
-
Nuclear orphan receptors control cholesterol catabolism
-
Russell D.W. Nuclear orphan receptors control cholesterol catabolism. Cell 97 (1999) 539-542
-
(1999)
Cell
, vol.97
, pp. 539-542
-
-
Russell, D.W.1
-
27
-
-
0013199471
-
Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXR alpha
-
Peet D.J., Turley S.D., Ma W., Janowski B.A., Lobaccaro J.M., Hammer R.E., and Mangelsdorf D.J. Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXR alpha. Cell 93 (1998) 693-704
-
(1998)
Cell
, vol.93
, pp. 693-704
-
-
Peet, D.J.1
Turley, S.D.2
Ma, W.3
Janowski, B.A.4
Lobaccaro, J.M.5
Hammer, R.E.6
Mangelsdorf, D.J.7
-
28
-
-
0029805887
-
An oxysterol signalling pathway mediated by the nuclear receptor LXR alpha
-
Janowski B.A., Willy P.J., Devi T.R., Falck J.R., and Mangelsdorf D.J. An oxysterol signalling pathway mediated by the nuclear receptor LXR alpha. Nature 383 (1996) 728-731
-
(1996)
Nature
, vol.383
, pp. 728-731
-
-
Janowski, B.A.1
Willy, P.J.2
Devi, T.R.3
Falck, J.R.4
Mangelsdorf, D.J.5
-
29
-
-
0037155163
-
Differential effects of sterol regulatory binding proteins 1 and 2 on sterol 12 alpha-hydroxylase. SREBP-2 suppresses the sterol 12 alpha-hydroxylase promoter
-
del Castillo-Olivares A., and Gil G. Differential effects of sterol regulatory binding proteins 1 and 2 on sterol 12 alpha-hydroxylase. SREBP-2 suppresses the sterol 12 alpha-hydroxylase promoter. J. Biol. Chem. 277 (2002) 6750-6757
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 6750-6757
-
-
del Castillo-Olivares, A.1
Gil, G.2
-
30
-
-
0033983170
-
Effects of simvastatin and pravastatin on gonadal function in male hypercholesterolemic patients
-
Dobs A.S., Miller S., Neri G., Weiss S., Tate A.C., Shapiro D.R., and Musliner T.A. Effects of simvastatin and pravastatin on gonadal function in male hypercholesterolemic patients. Metabolism 49 (2000) 115-121
-
(2000)
Metabolism
, vol.49
, pp. 115-121
-
-
Dobs, A.S.1
Miller, S.2
Neri, G.3
Weiss, S.4
Tate, A.C.5
Shapiro, D.R.6
Musliner, T.A.7
|