Glucocorticoid-dependent transcriptional repression of the osteocalcin gene by competitive binding at the TATA box

DNA and Cell Biology

Volumn 16, Issue 8, 1997, Pages 919-927

  Carlstedt Duke, Jan ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOCORTICOID; OSTEOCALCIN;

ARTICLE; BINDING SITE; CELL DIFFERENTIATION; COMPETITIVE INHIBITION; DIMERIZATION; DNA BINDING; EXTRACELLULAR MATRIX; HUMAN; HUMAN CELL; MINERALIZATION; PHOSPHATE METABOLISM; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN PROTEIN INTERACTION; RECEPTOR GENE; SIGNAL TRANSDUCTION; TATA BOX; TRANSCRIPTION REGULATION;

EID: 0030967927     PISSN: 10445498     EISSN: None     Source Type: Journal    
DOI: 10.1089/dna.1997.16.919     Document Type: Article

References (3)

1. AKERBLOM, I.E., SLATER, E.P., BEATO, M., BAXTER, J.D., and MELLON, P.L. (1988). Negative regulation by glucocorticoids through interference with a cAMP responsive enhancer. Science 241, 350-353.
2. ALAM, T., AN, M.R., MIFFLIN, R.C., HSIEH, C.C., GE, X., and PAPACONSTANTINOU, J. (1993). Trans-activation of the alpha 1-acid glycoprotein gene acute phase responsive element by multiple isoforms of C/EBP and glucocorticoid receptor. J. Biol. Chem. 268, 15681-15688.
3. ASLAM, F., SHALHOUB, V., VAN WIJNEN, A.J., BANERJEE, C., BORTELL, R., SHAKOORI, A.R., LITWACK, G., STEIN, J.L., STEIN, G.S., and LIAN, J.B. (1995). Contributions of distal and proximal promoter elements to glucocorticoid regulation of osteocalcin gene transcription. Mol. Endocrinol. 9, 679-690.